DOCSLIB.ORG

Infectious Diseases of Panama

Total Page：16

File Type：pdf, Size：1020Kb

Download full-text PDF Read full-text

Load more

INFECTIOUS DISEASES OF PANAMA Stephen Berger, MD Infectious Diseases of Panama - 2013 edition Infectious Diseases of Panama - 2013 edition Stephen Berger, MD Copyright © 2013 by GIDEON Informatics, Inc. All rights reserved. Published by GIDEON Informatics, Inc, Los Angeles, California, USA. www.gideononline.com Cover design by GIDEON Informatics, Inc No part of this book may be reproduced or transmitted in any form or by any means without written permission from the publisher. Contact GIDEON Informatics at [email protected]. ISBN-13: 978-1-61755-577-0 ISBN-10: 1-61755-577-0 Visit http://www.gideononline.com/ebooks/ for the up to date list of GIDEON ebooks. DISCLAIMER: Publisher assumes no liability to patients with respect to the actions of physicians, health care facilities and other users, and is not responsible for any injury, death or damage resulting from the use, misuse or interpretation of information obtained through this book. Therapeutic options listed are limited to published studies and reviews. Therapy should not be undertaken without a thorough assessment of the indications, contraindications and side effects of any prospective drug or intervention. Furthermore, the data for the book are largely derived from incidence and prevalence statistics whose accuracy will vary widely for individual diseases and countries. Changes in endemicity, incidence, and drugs of choice may occur. The list of drugs, infectious diseases and even country names will vary with time. Scope of Content: Disease designations may reflect a specific pathogen (ie, Adenovirus infection), generic pathology (Pneumonia - bacterial) or etiologic grouping (Coltiviruses - Old world). Such classification reflects the clinical approach to disease allocation in the Infectious Diseases Module of the GIDEON web application. Similarly, a number of diseases which are generally diagnosed and treated outside of the field of Infectious Diseases are not included, despite the fact that a clear infectious etiology exists. Examples include Peptic ulcer, Tropical spastic paraparesis, Hairy-cell leukemia, Creutzfeldt-Jakob disease, Human papilloma virus infections, etc. In contrast, a number of other entities of unknown etiology which do present to Infectious Diseases specialists have been included: Kawasaki's disease, Chronic fatigue syndrome, Kikuchi and Kimura diseases. Several minor infections having minimal relevance to the field of Geographic Medicine are not covered: Paronychia, Otitis externa, Molluscum contagiosum, etc. © 2013 GIDEON Informatics, Inc. www.gideononline.com All Rights Reserved. Page 1 of 388 Infectious Diseases of Panama - 2013 edition Introduction: The GIDEON e-book series Infectious Diseases of Panama is one in a series of GIDEON ebooks which summarize the status of individual infectious diseases, in every country of the world. Data are based on the GIDEON web application (www.gideononline.com) which relies on standard text books, peer-review journals, Health Ministry reports and ProMED, supplemented by an ongoing search of the medical literature. Chapters are arranged alphabetically, by disease name. Each section is divided into four sub-sections: 1. Descriptive epidemiology 2. Summary of clinical features 3. Status of the disease in Panama 4. References The initial items in the first section, Descriptive epidemiology, are defined as follows: Agent Classification (e.g., virus, parasite) and taxonomic designation. Reservoir Any animal, arthropod, plant, soil or substance in which an infectious agent normally lives and multiplies, on which it depends primarily for survival, and where it reproduces itself in such a manner that it can be transmitted to a susceptible host. Vector An arthropod or other living carrier which transports an infectious agent from an infected organism or reservoir to a susceptible individual or immediate surroundings. Vehicle The mode of transmission for an infectious agent. This generally implies a passive and inanimate (i.e., non-vector) mode. There are 348 generic infectious diseases in the world today. 221 of these are endemic, or potentially endemic, to Panama. A number of other diseases are not relevant to Panama and have not been included in this book. In addition to endemic diseases, we have included all published data regarding imported diseases and infection among expatriates from Panama. The availability and quality of literature regarding specific infectious diseases vary from country to country. As such, you may find that many of the sections in this book are limited to a general discussion of the disease itself - with no data regarding Panama. This is a book about the geography and epidemiology of Infection. Comprehensive and up-to-date information regarding the causes, diagnosis and treatment of each disease is available in the GIDEON web application. Many of the diseases are generic. For example, such designations as Pneumonia bacterial and Urinary tract infection include a number of individual diseases. These appear under the subheading, Synonyms, listed under each disease. We welcome feedback, and will be pleased to add any relevant, sourced material. Email us at [email protected] For more information about GIDEON see the section About GIDEON and visit www.gideononline.com Last updated: February 19, 2013 © 2013 GIDEON Informatics, Inc. www.gideononline.com All Rights Reserved. Page 2 of 388 Infectious Diseases of Panama - 2013 edition Table of Contents Introduction: The GIDEON e-book series ......................... 2 Diphtheria+ ................................................................88 Actinomycosis .............................................................. 6 Diphyllobothriasis ........................................................91 Adenovirus infection ..................................................... 8 Dipylidiasis .................................................................92 Aeromonas & marine Vibrio infx. .................................. 10 Dirofilariasis ...............................................................93 AIDS+....................................................................... 12 Eastern equine encephalitis+.........................................94 Amoeba - free living ................................................... 18 Echinococcosis - American polycystic+............................96 Amoebic abscess+ ...................................................... 20 Echinococcosis - unilocular ...........................................97 Amoebic colitis+ ......................................................... 21 Endocarditis - infectious ...............................................99 Angiostrongyliasis - abdominal+ ................................... 23 Enterobiasis.............................................................. 100 Animal bite-associated infection ................................... 24 Enterovirus infection+ ................................................ 101 Anisakiasis ................................................................ 25 Epidural abscess ....................................................... 103 Anthrax* ................................................................... 26 Erysipelas or cellulitis................................................. 104 Ascariasis+ ................................................................ 29 Erysipeloid ............................................................... 105 Aspergillosis .............................................................. 31 Erythrasma .............................................................. 106 Bacillary angiomatosis................................................. 32 Escherichia coli diarrhea ............................................. 107 Bacillus cereus food poisoning ...................................... 33 Filariasis - Bancroftian+ .............................................. 109 Bacterial vaginosis...................................................... 34 Fungal infection - invasive .......................................... 111 Balantidiasis .............................................................. 35 Gastroenteritis - viral................................................. 113 Bartonellosis - cat borne.............................................. 36 Gianotti-Crosti syndrome............................................ 114 Bartonellosis - other systemic ...................................... 38 Giardiasis+ ............................................................... 115 Blastocystis hominis infection....................................... 39 Gonococcal infection+ ................................................ 117 Botulism.................................................................... 40 Granuloma inguinale.................................................. 119 Brain abscess............................................................. 42 Group C viral fevers+ ................................................. 120 + Brucellosis ............................................................... 43 Hantavirus pulmonary syndrome+ ...............................121 + Bunyaviridae infections - misc. ................................... 47 Hepatitis A+.............................................................. 124 + California encephalitis group ...................................... 49 Hepatitis B+.............................................................. 126 Campylobacteriosis..................................................... 50 Hepatitis C+.............................................................
Recommended publications
  • Cutaneous Leishmaniasis Due to Leishmania (Viannia) Panamensis in Two Travelers Successfully Treated with Miltefosine

    Cutaneous Leishmaniasis Due to Leishmania (Viannia) Panamensis in Two Travelers Successfully Treated with Miltefosine

    Am. J. Trop. Med. Hyg., 103(3), 2020, pp. 1081–1084 doi:10.4269/ajtmh.20-0086 Copyright © 2020 by The American Society of Tropical Medicine and Hygiene Case Report: Cutaneous Leishmaniasis due to Leishmania (Viannia) panamensis in Two Travelers Successfully Treated with Miltefosine S. Mann,1* T. Phupitakphol,1 B. Davis,2 S. Newman,3 J. A. Suarez,4 A. Henao-Mart´ınez,1 and C. Franco-Paredes1,5 1Division of Infectious Diseases, University of Colorado School of Medicine, Aurora, Colorado; 2Division of Pathology, University of Colorado School of Medicine, Aurora, Colorado; 3Division of Dermatology, University of Colorado School of Medicine, Aurora, Colorado; 4Gorgas Memorial Institute of Tropical Medicine, Panama ´ City, Panama; ´ 5Hospital Infantil de Mexico, ´ Federico Gomez, ´ Mexico ´ City, Mexico ´ Abstract. We present two cases of Leishmania (V) panamensis in returning travelers from Central America suc- cessfully treated with miltefosine. The couple presented with ulcerative skin lesions nonresponsive to antibiotics. Skin biopsy with polymerase chain reaction (PCR) revealed L. (V) panamensis. To prevent the development of mucosal disease and avoid the inconvenience of parental therapy, we treated both patients with oral miltefosine. We suggest that milte- fosine represents an important therapeutic alternative in the treatment of cutaneous lesions caused by L. panamensis and in preventing mucosal involvement. A 31-old-man and a 30-year-old woman traveled to Costa Because of the presence of a thick fibrous scar at the ul- Rica for their honeymoon. They visited many regions of this cerative lesion border, we recommended a short course of country and participated in hiking, rafting, and camping.
  • Granuloma De Las Piscinas Carcinoma Basocelular Localmente Avanzado

    Granuloma De Las Piscinas Carcinoma Basocelular Localmente Avanzado

    Penfigoide gestacional pustuloso Granuloma facial de localización atípica Programa de Educación Médica Continua Variantes de Archivos Argentinos de Dermatología clínicas inusuales de Año 2019, volumen 5, número 4 sarcoidosis Octubre, Noviembre y Diciembre 2019. cutánea Precio: $200 Carcinoma basocelular localmente avanzado tratado con Vismodegib Granuloma de las piscinas www.archivosdermato.org.ar [email protected] Educando Nos Programa de Educación Médica Continua de Archivos Argentinos de Dermatología Año 2019, volumen 5, número 4 Sumario Octubre, Noviembre y Diciembre 2019 Editorial Acrodermatitis enteropática 3 Glorio Roberto 36 Ruiz Díaz María, Kuen Bernardita, Caggia Antonella, Díaz Ysabel, Lozinsky Liliana 4 Reglamento de publicaciones Jornadas de Educación 40 Médica Continua Granuloma facial de 6 localización atípica Carcinoma basocelular Digilio Marianela, Manzano Roxana, Bendjuia Gabriela, 42 localmente avanzado tratado Schroh Roberto, Feinsilber Daniel con Vismodegib Van Caester Leandro Rodolfo, Alfaro María Florencia, Consigli Javier, De La Colina Marcelo, Manrique Valeria, Variantes clínicas inusuales de Pereyra Susana Beatriz 10 sarcoidosis cutánea Espósito Daniela, Márquez, Juan Manuel, López Di Noto Ada Laura, Marcucci Carolina, Sánchez Graciela, Merola Gladys Seguimiento en pacientes 46 sensibilizados a Queratosis folicular invertida de metilisotiazolinona 18 localización infrecuente Russo Juan Pedro, Palazzolo Juan Francisco, Adorni Romina, Consigli Carlos Landau Débora, Caruso Territoriale Antonella, Valente
  • ﺑﺴﻢ اﷲ اﻟﺮﺣﻤﻦ اﻟﺮﺣﻴﻢ Molecular Characterization Of

    ﺑﺴﻢ اﷲ اﻟﺮﺣﻤﻦ اﻟﺮﺣﻴﻢ Molecular Characterization Of

    View metadata, citation and similar papers at core.ac.uk brought to you by CORE provided by KhartoumSpace ﺑﺴﻢ اﷲ اﻟﺮﺣﻤﻦ اﻟﺮﺣﻴﻢ Molecular Characterization of Pasteurella multocida Vaccine Strains By: Hajir Badawi Mohammed Ahmed B.V.M Khartoum University (2006) Supervisor: Dr. Awad A. Ibrahim A dissertation submitted to the University of Khartoum in partial fulfillment of the requirements for the degree of M. Sc. in Microbiology Department of Microbiology, Faculty of Veterinary Medicine, University of Khartoum June, 2010 Dedication To my mother Father Brother, sister and friends With great love Acknowledgments First and foremost, I would like to thank my Merciful Allah, the most beneficent for giving me strength and health to accomplish this work. Then I would like to deeply thank my supervisor Dr. Awad A. Ibrahim for his advice, continuous encouragement and patience throughout the period of this work. My gratitude is also extended to prof. Mawia M. Mukhtar and for Dr. Manal Gamal El-dein, Institute of Endemic Disease. My thanks extend to members of Department of Microbiology Faculty of Veterinary Medicine for unlimited assistant and for staff of Central Laboratory Soba. I am grateful to my family for their continuous support and standing beside me all times. My thanks also extended to all whom I didn’t mention by name and to the forbearance of my friends, and colleagues who helped me. Finally I am indebted to all those who helped me so much to make this work a success. Abstract The present study was carried out to study the national haemorrhagic septicaemia vaccine strains at their molecular level.
  • Psoriasis, a Systemic Disease Beyond the Skin, As Evidenced by Psoriatic Arthritis and Many Comorbities

    Psoriasis, a Systemic Disease Beyond the Skin, As Evidenced by Psoriatic Arthritis and Many Comorbities

    1 Psoriasis, a Systemic Disease Beyond the Skin, as Evidenced by Psoriatic Arthritis and Many Comorbities – Clinical Remission with a Leishmania Amastigotes Vaccine, a Serendipity Finding J.A. O’Daly Astralis Ltd, Irvington, NJ USA 1. Introduction Psoriasis is a systemic chronic, relapsing inflammatory skin disorder, with worldwide distribution, affects 1–3% of the world population, prevalence varies according to race, geographic location, and environmental factors (Chandran & Raychaudhuri, 2010; Christophers & Mrowietz, 2003; Farber & Nall, 1974). In Germany, 33,981 from 1,344,071 continuously insured persons in 2005 were diagnosed with psoriasis; thus the one year prevalence was 2.53% in the study group. Up to the age of 80 years the prevalence rate (range: 3.99-4.18%) was increasing with increasing age and highest for the age groups from 50 to 79 years The total rate of psoriasis in children younger than 18 years was 0.71%. The prevalence rates increased in an approximately linear manner from 0.12% at the age of 1 year to 1.2% at the age of 18 years (Schäfer et al., 2011). In France, a case-control study in 6,887 persons, 356 cases were identified (5.16%), who declared having had psoriasis during the previous 12 months (Wolkenstein et al., 2009). The prevalence of psoriasis analyzed across Italy showed that 2.9% of Italians declared suffering from psoriasis (regional range: 0.8-4.5%) in a total of 4109 individuals (Saraceno et al., 2008). The overall rate of comorbidity in subjects with psoriasis aged less than 20 years was twice as high as in subjects without psoriasis.
  • Relevance of Epidemiological Surveillance in Travelers: an Imported Case of Leishmania Tropica in Mexico

    Relevance of Epidemiological Surveillance in Travelers: an Imported Case of Leishmania Tropica in Mexico

    CASE REPORT http://doi.org/10.1590/S1678-9946202062041 Relevance of epidemiological surveillance in travelers: an imported case of Leishmania tropica in Mexico Edith Araceli Fernández-Figueroa 1,2, Sokani Sánchez-Montes 2, Haydee Miranda-Ortíz 3, Alfredo Mendoza-Vargas 3, Rocely Cervantes-Sarabia4, Roberto Alejandro Cárdenas-Ovando 5, Adriana Ruiz-Remigio4, Ingeborg Becker 2,4 ABSTRACT We report the case of a patient with cutaneous leishmaniasis who showed a rapidly progressing ulcerative lesion after traveling to multiple countries where different Leishmania species are endemic. Diagnosis of Leishmania tropica, an exotic species in Mexico was established by using serological and molecular tools. KEYWORDS: Leishmania tropica. Molecular epidemiology. Local cutaneous leishmaniasis. Travel medicine. 1Instituto Nacional de Medicina Genómica, Departamento de Genómica Poblacional, Genómica Computacional e Integrativa, Ciudad de México, Mexico INTRODUCTION 2Universidad Nacional Autónoma de México, Facultad de Medicina, Unidad de Human cutaneous leishmaniasis is a zoonotic emerging tropical disease caused Investigación en Medicina Experimental, by 20 species of flagellated protozoa of the genus Leishmania, generating 150,000 Centro de Medicina Tropical, Ciudad de new human cases per year, that are distributed across 98 countries throughout the Old México, Mexico World and the New World1-3. Most of the Old World cases are caused by Leishmania 3Instituto Nacional de Medicina Genómica, aethiopica, Leishmania infantum, Leishmania major and Leishmania
  • Bacterial Soft Tissue Infections Following Water Exposure

    Bacterial Soft Tissue Infections Following Water Exposure

    CHAPTER 23 Bacterial Soft Tissue Infections Following Water Exposure Sara E. Lewis, DPM Devin W. Collins, BA Adam M. Bressler, MD INTRODUCTION to early generation penicillins and cephalosporins. Thus, standard treatments include fluoroquinolones (ciprofloxacin, Soft tissue infections following water exposure are relatively levofloxacin), third and fourth generation cephalosporins uncommon but can result in high morbidity and mortality. (ceftazidime, cefepime), or potentially trimethoprim-sulfa These infections can follow fresh, salt, and brackish water (4). However, due to the potential of emerging resistance exposure and most commonly occur secondary to trauma. seen in Aeromonas species, susceptibilities should always be Although there are numerous microorganisms that can performed and antibiotics adjusted accordingly (3). It is cause skin and soft tissue infections following water important to maintain a high index of suspicion for Aeromonas exposure, this article will focus on the 5 most common infections after water exposure in fresh and brackish water bacteria. The acronym used for these bacteria--AEEVM, and to start the patient on an appropriate empiric antibiotic refers to Aeromonas species, Edwardsiella tarda, Erysipelothrix regimen immediately. rhusiopathiae, Vibrio vulnificus, and Mycobacterium marinum. EDWARDSIELLA TARDA AEROMONAS Edwardsiella tarda is part of the Enterobacteriaceae family. Aeromonas species are gram-negative rods found worldwide in It is a motile, facultative anaerobic gram-negative rod fresh and brackish water (1-3). They have also been found in that can be found worldwide in pond water, mud, and contaminated drinking, surface, and polluted water sources the intestines of marine life and land animals (5). Risk (3). Aeromonas are usually non-lactose fermenting, oxidase factors for infection include water exposure, exposure positive facultative anaerobes.
  • WO 2014/134709 Al 12 September 2014 (12.09.2014) P O P C T

    WO 2014/134709 Al 12 September 2014 (12.09.2014) P O P C T

    (12) INTERNATIONAL APPLICATION PUBLISHED UNDER THE PATENT COOPERATION TREATY (PCT) (19) World Intellectual Property Organization International Bureau (10) International Publication Number (43) International Publication Date WO 2014/134709 Al 12 September 2014 (12.09.2014) P O P C T (51) International Patent Classification: (81) Designated States (unless otherwise indicated, for every A61K 31/05 (2006.01) A61P 31/02 (2006.01) kind of national protection available): AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, (21) International Application Number: BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, PCT/CA20 14/000 174 DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, (22) International Filing Date: HN, HR, HU, ID, IL, IN, IR, IS, JP, KE, KG, KN, KP, KR, 4 March 2014 (04.03.2014) KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, (25) Filing Language: English OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, (26) Publication Language: English SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, (30) Priority Data: ZW. 13/790,91 1 8 March 2013 (08.03.2013) US (84) Designated States (unless otherwise indicated, for every (71) Applicant: LABORATOIRE M2 [CA/CA]; 4005-A, rue kind of regional protection available): ARIPO (BW, GH, de la Garlock, Sherbrooke, Quebec J1L 1W9 (CA). GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, SZ, TZ, UG, ZM, ZW), Eurasian (AM, AZ, BY, KG, KZ, RU, TJ, (72) Inventors: LEMIRE, Gaetan; 6505, rue de la fougere, TM), European (AL, AT, BE, BG, CH, CY, CZ, DE, DK, Sherbrooke, Quebec JIN 3W3 (CA).
  • Kikuchi Disease with Generalized Lymph Node, Spleen And

    Kikuchi Disease with Generalized Lymph Node, Spleen And

    Case Report Mol Imaging Radionucl Ther 2016;25:102-106 DOI:10.4274/mirt.25338 Kikuchi Disease with Generalized Lymph Node, Spleen and Subcutaneous Involvement Detected by Fluorine-18-Fluorodeoxyglucose Positron Emission Tomography/Computed Tomography Flor-18-Florodeoksiglukoz Pozitron Emisyon Tomografisi/Bilgisayarlı Tomografi ile Saptanan Yaygın Lenf Nodu, Dalak ve Deri Altı Tutulumu Olan Kikuchi Hastalığı Alshaima Alshammari1, Evangelia Skoura2, Nafisa Kazem1, Rasha Ashkanani1 1Mubarak Al Kabeer Hospital, Clinic of Nuclear Medicine, Jabriya, Kuwait 2University College London Hospital, Clinic of Nuclear Medicine, London, United Kingdom Abstract Kikuchi-Fujimoto disease, known as Kikuchi disease, is a rare benign and self-limiting disorder that typically affects the regional cervical lymph nodes. Generalized lymphadenopathy and extranodal involvement are rare. We report a rare case of a 19-year- old female with a history of persistent fever, nausea, and debilitating malaise. Fluorine-18-fluorodeoxyglucose positron emission tomography/computed tomography (18F-FDG PET/CT) revealed multiple hypermetabolic generalized lymph nodes in the cervical, mediastinum, axillary, abdomen and pelvic regions with diffuse spleen, diffuse thyroid gland, and focal parotid involvement, bilaterally. In addition, subcutaneous lesions were noted in the left upper paraspinal and occipital regions. An excisional lymph node biopsy guided by 18F-FDG PET/CT revealed the patient’s diagnosis as Kikuchi syndrome. Keywords: Kikuchi-Fujimoto disease, histiocytic necrotizing lymphadenitis, fluorine-18-fluorodeoxyglucose Öz Kikuchi hastalığı olarak bilinen Kikuchi-Fujimoto hastalığı, genellikle bölgesel servikal lenf düğümlerini etkileyen, nadir görülen benign ve kendini sınırlayıcı bir hastalıktır. Yaygın lenfadenopati ve ekstranodal tutulum nadirdir. Bu yazıda sürekli ateş, bulantı ve halsizlik şikayetleri olan 19 yaşında bir kadın hasta sunulmaktadır.
  • Identification of Pasteurella Species and Morphologically Similar Organisms

    Identification of Pasteurella Species and Morphologically Similar Organisms

    UK Standards for Microbiology Investigations Identification of Pasteurella species and Morphologically Similar Organisms Issued by the Standards Unit, Microbiology Services, PHE Bacteriology – Identification | ID 13 | Issue no: 3 | Issue date: 04.02.15 | Page: 1 of 28 © Crown copyright 2015 Identification of Pasteurella species and Morphologically Similar Organisms Acknowledgments UK Standards for Microbiology Investigations (SMIs) are developed under the auspices of Public Health England (PHE) working in partnership with the National Health Service (NHS), Public Health Wales and with the professional organisations whose logos are displayed below and listed on the website https://www.gov.uk/uk- standards-for-microbiology-investigations-smi-quality-and-consistency-in-clinical- laboratories. SMIs are developed, reviewed and revised by various working groups which are overseen by a steering committee (see https://www.gov.uk/government/groups/standards-for-microbiology-investigations- steering-committee). The contributions of many individuals in clinical, specialist and reference laboratories who have provided information and comments during the development of this document are acknowledged. We are grateful to the Medical Editors for editing the medical content. For further information please contact us at: Standards Unit Microbiology Services Public Health England 61 Colindale Avenue London NW9 5EQ E-mail: [email protected] Website: https://www.gov.uk/uk-standards-for-microbiology-investigations-smi-quality- and-consistency-in-clinical-laboratories UK Standards for Microbiology Investigations are produced in association with: Logos correct at time of publishing. Bacteriology – Identification | ID 13 | Issue no: 3 | Issue date: 04.02.15 | Page: 2 of 28 UK Standards for Microbiology Investigations | Issued by the Standards Unit, Public Health England Identification of Pasteurella species and Morphologically Similar Organisms Contents ACKNOWLEDGMENTS .........................................................................................................
  • A Resident's Guide to Pediatric Rheumatology

    A Resident's Guide to Pediatric Rheumatology

    A RESIDENT’S GUIDE TO PEDIATRIC RHEUMATOLOGY 4th Revised Edition - 2019 A RESIDENT’S GUIDE TO PEDIATRIC RHEUMATOLOGY This guide is intended to provide a brief introduction to basic topics in pediatric rheumatology. Each topic is accompanied by at least one up-to-date reference that will allow you to explore the topic in greater depth. In addition, a list of several excellent textbooks and other resources for you to use to expand your knowledge is found in the Appendix. We are interested in your feedback on the guide! If you have comments or questions, please feel free to contact us via email at [email protected]. Supervising Editors: Dr. Ronald M. Laxer, SickKids Hospital, University of Toronto Dr. Tania Cellucci, McMaster Children’s Hospital, McMaster University Dr. Evelyn Rozenblyum, St. Michael’s Hospital, University of Toronto Section Editors: Dr. Michelle Batthish, McMaster Children’s Hospital, McMaster University Dr. Roberta Berard, Children’s Hospital – London Health Sciences Centre, Western University Dr. Liane Heale, McMaster Children’s Hospital, McMaster University Dr. Clare Hutchinson, North York General Hospital, University of Toronto Dr. Mehul Jariwala, Royal University Hospital, University of Saskatchewan Dr. Lillian Lim, Stollery Children’s Hospital, University of Alberta Dr. Nadia Luca, Alberta Children’s Hospital, University of Calgary Dr. Dax Rumsey, Stollery Children’s Hospital, University of Alberta Dr. Gordon Soon, North York General Hospital and SickKids Hospital Northern Clinic in Sudbury, University
  • Retrospective Study of Aeromonas Infection in a Malaysian Urban Area: a 10-Year Experience W S Lee, S D Puthucheary

    Retrospective Study of Aeromonas Infection in a Malaysian Urban Area: a 10-Year Experience W S Lee, S D Puthucheary

    Singapore Med J 2001 Vol 42(2) : 057-060 Original Article Retrospective Study of Aeromonas Infection in a Malaysian Urban Area: A 10-year Experience W S Lee, S D Puthucheary ABSTRACT Keywords: Aeromonas, gastroenteritis, childhood Aims: To describe the patterns of isolation of Singapore Med J 2001 Vol 42(2):057-060 Aeromonas spp. and the resulting spectrum of infection, intestinal and extra-intestinal, from infants INTRODUCTION and children in an urban area in a hot and humid A variety of human infections, including gastroenteritis, country from Southeast Asia. cellulitis, wound infections, hepatobiliary infections and Materials and methods: Retrospective review of all septicaemia have been reported to be associated with bacterial culture records from children below 16 Aeromonas spp.(1,2). At least three distinctive gastro- years of age, from the Department of Medical intestinal syndromes following gastroenteritis caused by Microbiology, University of Malaya Medical Centre, of Aeromonas sp. have been described: (a) acute, watery Kuala Lumpur, from January 1988 to December 1997. diarrhoea; (b) dysentery; and (c) subacute or chronic Review of all stool samples and rectal swabs obtained diarrhoea(3). Acute watery diarrhoea was self-limiting(4,5). from children during the same period were carried Dysentery-like illness with bloody and mucousy out to ascertain the isolation rate of Aeromonas sp. diarrhoea, mimicking childhood inflammatory bowel from stools and rectal swabs. The case records of disease was seen occasionally(3). The highest attack rate those with a positive Aeromonas culture were for Aeromonas-associated gastroenteritis appears to be retrieved and reviewed. in young children(4). A wide difference in the frequency of isolation of Aeromonas spp.
  • Focus: Blood Cancer

    Focus: Blood Cancer

    JAN-MAR 17 www.singhealth.com.sg A SingHealth Newsletter for Medical Practitioners MCI (P) 027/11/2016 FOCUS: BLOOD CANCER Haematologic Emergencies An Overview of in the General Practice Myeloproliferative Neoplasms When to Suspect Approach to an Adult with Myeloma in Primary Care Lymphadenopathy in Primary Care SingHealth Duke-NUS Academic Medical Centre • Singapore General Hospital • KK Women’s and Children’s Hospital • Sengkang Health • National Cancer Centre Singapore • National Dental Centre of Singapore • National Heart Centre Singapore • National Neuroscience Institute • Singapore National Eye Centre • SingHealth Polyclinics • Bright Vision Hospital Medical Appointments: 6321 4402 (SGH) Focus: Update Blood Cancer 6436 8288 (NCCS) Haematologic Emergencies in the General Practice Adj Assoc Prof Wong Gee Chuan, Senior Consultant, Department of Haematology, Singapore General Hospital; SingHealth Duke-NUS Blood Cancer Centre Patients with malignant haematological diseases may present with dramatic and life-threaten- ing complications. General physicians must be able to recognise these conditions as prompt treatment can be life-saving. Hyperleukocytosis and leukostasis and febrile neutropaenia in patients with haematologic malignancies are two such conditions highlighted in this article. mental state and unsteadiness in gait. patient presents with a high white cell HYPERLEUKOCYTOSIS AND There is also increased risk of intracra- count and symptoms suggestive of tis- LEUKOSTASIS IN HAEMATOLOGIC nial haemorrhage. sue hypoxia. MALIGNANCIES Besides affecting the central nervous Hyperleukocytosis has been variably system, eyes and lungs, other manifes- Leukostasis constitutes a medi- defined as a total white cell count tations include myocardial ischaemia, cal emergency. Prompt treatment (WBC) of 50 x 109/L or 100 x 109/L. Leu- limb ischaemia or bowel infarction.