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SPRINGER NATURE EXPERIMENTS The advanced solution that helps you discover the most relevant protocols and methods for your research • Enable the right experiments • Get results • Accelerate research projects 2 Springer Nature Experiments springernature.com

The importance of finding the right protocols and methods

Save valuable The challenge time Experiments are at the core of laboratory research, with researchers investing a significant amount of their time designing reproducible experiments in an attempt to reach a defined result. Multiple information sources are used to design an experiment suitable for their laboratory set-up and the research question they are attempting to answer. Two of the most critical sources are: • Protocols – step-by-step instructions that include information on materials required, equipment set-up and more • Methods – new or significantly improved procedures to solve specific problems To speed up the process of finding relevant information sources, researchers skim through article after article, looking for keywords such as techniques, organisms, reagents, and figures or schemes that tell them the article is worth further evaluation. They also draw upon other types of information such as analyses, perspectives, and reviews to get a greater context and decide which actions to take.

The solution We take the largest and best quality collection of available protocols and methods for the life sciences and apply cutting-edge AI and text-mining technologies to identify techniques and organisms mentioned in the content.

Springer Nature Experiments brings together the largest and best quality collection of protocols and methods for the life sciences Springer Nature Experiments springernature.com 3

Find

One search spans Springer Nature vast protocols and methods content – the largest available resource for the life sciences, with more than 60,000 articles from the trusted Nature Methods, Nature Protocols, and SpringerProtocols. Numerous users interviews have highlighted that researchers look for laboratory procedures using specific research techniques, model organisms or cell lines. That's the reason why our algorithm automatically recognizes these concepts in a search query and only returns the protocols and methods that use them. Users can then use any of the available filters to further refine results: • Publication year – users can filter through more than 30 years of articles or pinpoint a specific year or time period • Video – researchers can refine their search results to articles including a video to help with their most complex experiments • Techniques – from simple techniques to the most complicated procedures, researchers can select a suitable methodology for their project • Article category – users can choose from different types of content including protocols, overviews, reviews and research • Source – researchers can select their publications of interest or search across the whole Springer Nature protocols and methods portfolio. Springer Nature Experiments springernature.com 4

Evaluate

At a glance evaluation of your search results Highlighting techniques used as well as citations or downloads help researchers make a quick assessment and decide whether to expand or refine their investigation. Users also have the option to sort results in the way that makes the most sense to their search: • Relevance – based on the presence of the search terms in the content of the article • Most recent – based on the article’s publication date • Most cited – based on the number of times the article was cited in scientific works • Trending – based on the number of times the article was downloaded in the last thirty days In-depth article evaluation page

Full abstract and reference list – as originally published Clicking on one of the search results will open a dedicated page Keywords – they list the main research techniques used in the article with key information needed for in-depth evaluation and comparison Citation history – gives the user confidence that the protocol or method of the protocols and methods is being successfully and consistently used in other research projects Article history – lists any previous versions of the article or any corrections Figures and videos – allow the user to browse over the figures and videos contained in the article Recent citations – show the user where the protocol or method was last used Author's contact and affiliation– learn more about the author and access their email when provided Related articles – Explore relevant protocols and methods using similar research techniques 5 Springer Nature Experiments springernature.com

Springer Nature protocols and methods portfolio

Springer Nature Experiments brings together the Springer Nature Protocols and Methods portfolio, allowing users to efficiently search across the largest available resource for the life sciences, including:

Nature Methods • Detailed description of cutting-edge methodological approaches aimed at solving important biological questions • Primary research papers with an array of cutting-edge articles, opinions and news • Publishes monthly with approximately 360 articles per year 5,000+ articles* Nature Protocols • Comprehensive protocols covering the techniques that have been used to achieve results recently published in top-tier journals, as well as classic and well-established protocols • Faster for publishing protocols for new techniques • Publishes monthly with approximately 200 protocols per year 2,500+ protocols* SpringerProtocols • Building on the heritage of the Methods in Molecular Biology book series, SpringerProtocols covers 30 years of tried and tested laboratory procedures • The largest collection of laboratory protocols, covering a wide scope of research topics 50,000+ protocols* • 180 book volumes and approximately 3,000 protocols published every year Once users have identified the most relevant protocols and methods, they can link directly to the content on its native platform – nature.com for Nature Methods and Nature Protocols or SpringerLink for SpringerProtocols. Subscriptions are required to access the full-text content, with the exception of some open-access SpringerProtocols * September 2018 figures books. The combined portfolio of Springer Nature’s protocols and methods provides unequalled scale and quality to help accelerate research projects and advance discovery.

Subject areas covered include:

• Biochemistry • Imaging • Pharmacology and • Bioinformatics • Immunology Toxicology • Biotechnology • Infectious Diseases • Plant Science • Cancer Research • Microbiology • Protein Science • Cell Biology • Molecular Medicine • Genetics/Genomics • Neuroscience springernature.com

Research benefits of Springer Nature Experiments

• Search across the largest and most comprehensive collection of protocols and Try Springer Nature methods for the life sciences Experiments now at • Springer Nature portfolio gathers the oldest and most prestigious books and experiments.springernature.com journals in the methods and protocols field • Quickly identify the most relevant protocols and methods for your research with the help of sophisticated search filters driven by cutting-edge AI and text-mining technologies • Evaluate and compare protocols by highlighting techniques used or citations to confidently choose the best protocol for your own experiment.

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