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Weill Medical College of Cornell University Required Format For CHARLES L. SAWYERS, MD Address: Phone: Fax: Email: EDUCATIONAL BACKGROUND Degree Institution name and location Dates attended Year awarded B.A. Princeton University, Princeton, NJ 1977–1981 1981 M.D. Johns Hopkins, Baltimore, MD 1981–1985 1985 PROFESSIONAL POSITIONS AND EMPLOYMENT Post-doctoral training (residency/fellowships) Title Institution name and location Dates held Internship & University of California, San Francisco 1985 – 1988 Residency Dept. of Medicine, San Francisco, CA Fellow University of California, Los Angeles 1988 – 1991 Division of Hematology-Oncology, Department of Medicine, Los Angeles, CA Post-doctoral UCLA/Howard Hughes Medical Institute 1989 – 1993 training Dr. Owen N. Witte, Professor of Microbiology & Molecular Genetics Los Angeles, CA Academic positions (teaching and research) Title Institution name and location Dates held Clinical University of California, Los Angeles 1991 – 1993 Instructor Division of Hematology-Oncology, Department of Medicine Assistant University of California, Los Angeles 1993 – 1997 Professor Division of Hematology-Oncology, Department of Medicine 1 Member University of California, Los Angeles 1993 – 2006 Jonsson Comprehensive Cancer Center Full Member University of California, Los Angeles 1993 – 2006 Molecular Biology Institute Associate University of California, Los Angeles 1996 – 2006 Chief Basic Research, Division of Hematology- Oncology, Department of Medicine Associate University of California, Los Angeles 1997 – 2000 Professor Division of Hematology-Oncology Department of Medicine Professor University of California, Los Angeles 2000 – 2006 Division of Hematology-Oncology Department of Medicine Joint Appt. University of California, Los Angeles 2000 – 2006 Department of Urology Joint Appt. University of California, Los Angeles 2000 – 2006 Department of Molecular & Medical Pharmacology Member Memorial Sloan-Kettering Cancer Center 2006 – Present New York, NY Professor Joan & Sanford Weill Graduate School 2011 - Present of Medical Sciences of Cornell University Cell and Developmental Biology Program Hospital positions Title Institution name and location Dates held Attending UCLA Medical Center 1991 – 2006 Los Angeles, CA Director University of California, Los Angeles 1996 – 1998 Hematopoietic Malignancies and BMT Program Area, Jonsson Comprehensive Cancer Center 2 Director University of California, Los Angeles 1998 – 2006 Genitourinary Cancer Program Area Jonsson Comprehensive Cancer Center Investigator Howard Hughes Medical Institute 2002 – 2006 Los Angeles, CA 2008-present Vice Chair University of California, Los Angeles 2005 – 2006 Department of Molecular & Medical Pharmacology Attending Memorial Hospital for Cancer and Allied 2006 – Present Diseases, New York, NY Leukemia Service, Department of Medicine Chair Human Oncology and Pathogenesis 2006 – Present Program (HOPP) PROFESSIONAL MEMBERSHIP (in chronological order) Member American Society of Hematology (ASH) 1993 – Present Member American Association for 1998 – Present Cancer Research (AACR) Member American Society of Clinical 1999 – Present Investigation (ASCI) Subcommittee American Association for 1999 – 2000 Chair Cancer Research (AACR) Scientific American Society for Clinical 2001 – 2003 Program Cmte Oncology (ASCO) Organizer National Cancer Institute (NCI) 2002 Joint meeting of the Mouse Models of Human Cancers Consortium (MMHCC) and the Prostate SPOREs Program AACR/NCI/EORTC 2002 – 2003 Cmte Chair Meeting on Molecular Targets Scientific American Society of Hematology 2002 – 2005 Program Cmte 3 Program AACR Aspen Cancer Course 2004 – Present Director Organizer Mouse Models of Human Cancer 2004 Consortium Meeting Co-organizer Keystone Symposium Meeting 2004 “Protein Kinases and Cancer: The Promise of Molecularly Targeted Therapy” Course Director American Association for Cancer 2004 – 2008 Research (AACR) “Molecular Biology in Clinical Oncology,” Aspen, CO Co-organizer Cold Spring Harbor Cancer 2004, 2006 Genetics Meeting Co-chair William Guy Forbeck Research 2004 Foundation 2004 Forum, “Molecular Targets in Pediatric Malignancies,” Hilton Head, SC Chair American Society of Hematology (ASH) 2004 – 2006 Scientific Committee on Neoplasia Vice President, American Society of Clinical Investigation 2005 – 2008 President-Elect, (ASCI) and President Co-organizer Keystone Symposium Meeting on 2006 Cancer and Kinases: Lessons from the Clinic, Santa Fe, NM Scientific AACR Annual Meeting 2007 Program Cmte Co-Chair Pezcoller Foundation Symposium 2007 Member Institute of Medicine 2008 National Academy of Science 2010 Co-Chair Cold Spring Harbor 2008 Nuclear Receptors Meeting 4 President American Association of Cancer Research 2013-2014 Member American Academy of Arts and Sciences 2014 HONORS AND AWARDS (in chronological order) Name of award Date awarded Summa Cum Laude - History of Science Department 1981 Princeton University National Cancer Institute Physician Scientist Award 1990 – 1995 Howard Hughes Medical Institute 1991 – 1993 Physician Research Fellow Stop Cancer Career Research Award 1993 – 1996 Cheryl Whitlock Memorial Prize for Leukemia Research 1994 James S. McDonnell Foundation Scholar 1994 – 1997 Leukemia Society of America Scholar 1995 – 2000 Franklin D. Murphy Prize 1998 American Society for Clinical Investigation 1999 Stohlman Scholar Award 2000 The Leukemia and Lymphoma Society Recipient of Endowed Chair 2000 Peter Bing Chair of Urologic Research Doris Duke Distinguished Clinical Scientist Award 2001 Investigator, Howard Hughes Medical Institute 2002 Bristol-Myers-Squibb Freedom-to-Explore 2003 Unrestricted Research Award in Cancer UCSD-Nature Medicine Translational Medicine Award 2003 5 Plenary Session Talk at American Society of Hematology 2004 (ASH) (Abstract #1) “Hematologic and Cytogenic Responses in Imatinib Resistant CML Patients Treated with BMS 354825,” San Diego, CA American Association of Clinical Research (AACR) 2005 Richard and Hinda Rosenthal Foundation Award American Society of Clinical Oncology (ASCO) 2005 David A. Karnofsky Memorial Award Elected President, American Society of Clinical 2005 Investigation (ASCI) Emil Freireich Award 2007 Elected to membership, Institute of Medicine, NAS 2008 Dorothy Landon-AACR Prize for Translational Cancer Research 2009 Lasker~DeBakey Clinical Medical Research Award 2009 Elected to membership, National Academy of Sciences 2010 Stanley J. Korsmeyer Award 2011 American Society of Clinical Investigation (ASCI) Science of Oncology Award 2013 American Society of Clinical Oncology (ASCO) Taubman Prize for Excellence in Translational Medical Science 2013 Giants of Cancer Care Award 2013 Breakthrough Prize in Life Sciences 2013 Hope Funds for Cancer Research Honoree 2014 CURRENT AND PAST INSTITUTIONAL RESPONSIBILITIES Teaching/Mentoring Admissions Committee, Medical Scientist Training 1994 – 1999 Program, UCLA 6 Molecular Biology 298 Instructor, UCLA 1994 – 2006 Medical Internship Selection Committee, UCLA 1995 – 2000 Hematology-Oncology Fellowship Selection 1995 – 2002 Committee, UCLA Faculty Member of Ph.D. Program in Molecular 2001 – 2006 Biology Interdepartmental Degree Programs, UCLA Pharmacology 288 Instruction, UCLA 2002 – 2006 Doctoral Committee in Molecular Biology 2002 – 2006 UCLA Graduate Division Section Leader, Cancer Biology in the Core Curriculum 2006 – Present Course for Gerstner Sloan-Kettering Graduate School, MSKCC Lecturer, Molecular Biology of Cancer Course 2006 – Present Tri-Institutional MD, PhD Program Clinical care (duties, dates) Clinical In-patient Rounds, UCLA 1993 – 2006 Continuity Clinic in Hematology/Oncology, UCLA 1991 – 2006 Administrative duties, including committees, dates UCLA Jonsson Cancer Center Signal Transduction 1993 – 1997 Program Search Committee Jonsson Comprehensive Cancer Center, Clinical 1994 – 2002 Research Seed Grants Review Committee, UCLA Organizer of UCLA Cancer Center Research Conference 1995 – 1999 Co-Organizer of UCLA Parvin Cancer Symposium, 1995 “Abnormal Signal Transduction in Human Cancer,” (with Dr. Chris Denny, Pediatrics) Gene Therapy Program Seed Grant Review Panel, UCLA 1995 – 1998 7 Dept. of Medicine Specialty Training and Advanced 1995 – 2000 Research (STAR) Executive Committee, UCLA Organizer of monthly Prostate Cancer Research 1998 – 2006 Conferences, UCLA UCLA Institutional Representative to American Society 2001 – 2006 Of Clinical Investigation (ASCI) Associate Member, Crump Institute for Molecular 2002 – 2006 Imaging, UCLA Memorial Hospital Committee on Credentialing and 2006 – Present Privileging (MHCCP), MSKCC Correlative Science Assessment Team (CSAT) for 2006 – Present Phase I/II Clinical Contracts (D. Kelsen, PI), MSKCC MSKCC Prostate SPORE, Advisory Board 2006 – Present (P. Scardino, PI) MSKCC Cancer Genome Characterization Center 2006 – Present Advisory Board (M. Ladanyi, PI) RESEARCH SUPPORT ACTIVE RESEARCH SUPPORT Howard Hughes Medical Institute (Sawyers) 3/1/08- Major Goals of this project: Patient oriented research into molecularly targeted therapy of cancer R01-CA155169 (Sawyers) 5/1/12-3/31/17 NCI/NIH Understanding Resistance to Next Generation Antiandrogens Specific Aims: To explore the molecular basis by whichGR selectively activates certain AR target genes (Aim 1), the functional role of GR, AR and theGR/AR target gene SGK1 in maintaining drug resistance (Aim 2), and the clinical relevance ofthese findings in circulating tumor cells obtained from patients at treatment start and at relapse (Aim 3). P50-CA092629 (Scher) 9/1/08 – 8/31/16 National Institutes of Health MSKCC Spore
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