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Lebanon Substitution Drug List

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Lebanon Substitution Drug List LEBANON SUBSTITUTION DRUG LIST First Edition 2015 Ministry of Public Health of Lebanon This list was prepared under the guidance of His Excellency Minister Wael Abou Faour and the supervision of the Director General Dr. Walid Ammar. Editors Rita KARAM, Pharm D. PhD. Diana CHARBEL, Pharm D. Ghassan HAMADEH, MD.CPE Acknowledgments This Substitution Drug list was made possible with the help and support of many stakeholders. We wish to acknowledge the following specifically: • Ministry of Public Health staff in the Pharmacy Service headed by Dr. Colette Raidy • Dr. Myriam Watfa who helped in collection and revision of data. iv Foreword According to the Law No. 91 issued on 2010 related to the Pharmacist substitution right, the Ministry of Public Health conceived the Substitution Drug list. It is presented as a scientific, objective, reliable, accurate and accessible listing. This list is a helpful tool for Pharmacists and Health professionals and an information tool for patients as well. The Substitution Drug List was compiled by a team of Pharmacists and Physicians from the Ministry of Public Health. It was inspired by the French Repertory of Generic Groups and the Lebanese National Drug Index (LNDI) which is the reference Guide for medicines in Lebanon. The substitution could be done between an innovator product and a generic, based on the Ministry of Public Health Substitution list, providing that the product delivered is cheaper and has obtained the patient’s consent. This Substitution Drug List, lists drugs, dosage forms, package sizes, drug strengths and other information registered at the Ministry of Public Health. It is divided into sections based on the Anatomical Therapeutic Chemical (ATC) classification system. The Innovator product is listed before the Generic products. Information is shown in a convenient format with trade information in italics: ATCcode B=Brand Trade Name & Strength G=Generic Registration Number at Route Form Container Presentation Code MOPH MOPH Active Ingredients with their respective dosage Agent importing product Manufacturer Country of Origin Responsible Party Country of Responsible Party Each medication listing contains the following information: • ATC classification and code. • Trade name and strength of the formulation as registered at the Ministry of Public Health (MOH) • Generic (G) or Brand product (B) • Composition of the marketed form with the corresponding dosage of each active ingredient. • Form &presentation. • The local importer (agent), manufacturer and identified country of origin. • The Responsible Party and identified country. • The Ministry of Public Health database serial number (Code MOH) and legal registration document number (MOH reg) The Substitution Drug List can be accessed from the official website of the Ministry of Public Health: www.moph.gov.lb The Substitution Drug List welcomes comments from healthcare professionals. Please send comments to: [email protected] Walid Ammar MD, Ph.D Director General Ministry of Public Health v vi Table of Contents Acknowledgments ............................................................................... Error! Bookmark not defined. Table of Contents ................................................................................................................................. vii A ALIMENTARY TRACT AND METABOLISM .......................................................................... 1 A01 STOMATOLOGICAL PREPARATIONS ............................................................................ 1 A02 DRUGS FOR ACID RELATED DISORDERS .................................................................... 2 A03 DRUGS FOR FUNCTIONAL GASTROINTESTINAL DISORDERS ............................... 9 A04 ANTIEMETICS AND ANTINAUSEANTS ....................................................................... 12 A05 BILE AND LIVER THERAPY ........................................................................................... 12 A06 LAXATIVES ....................................................................................................................... 12 A07 ANTIDIARRHEALS, INTESTINAL ANTIINFLAMMATORY/ANTIINFECTIVE AGENTS .......................................................................................................................................... 14 A08 ANTIOBESITY PREPARATIONS, EXCL. DIET PRODUCTS ....................................... 14 A10 DRUGS USED IN DIABETES ........................................................................................... 15 A11 VITAMINS .......................................................................................................................... 25 A12 MINERAL SUPPLEMENTS .............................................................................................. 26 C CARDIOVASCULAR SYSTEM ................................................................................................ 27 C01 CARDIAC THERAPY ........................................................................................................ 27 C02 ANTIHYPERTENSIVES .................................................................................................... 28 C03 DIURETICS ......................................................................................................................... 29 C04 PERIPHERAL VASODILATORS ...................................................................................... 29 C07 BETA BLOCKING AGENTS ............................................................................................. 30 C08 CALCIUM CHANNEL BLOCKERS ................................................................................. 35 C09 AGENTS ACTING ON THE RENIN-ANGIOTENSIN SYSTEM .................................... 40 C10 SERUM LIPID REDUCING AGENTS .............................................................................. 55 D DERMATOLOGICALS .............................................................................................................. 70 D01 ANTIFUNGALS FOR DERMATOLOGICAL USE .......................................................... 70 D02 EMOLLIENTS AND PROTECTIVES ............................................................................... 73 D03 PREPARATIONS FOR TREATMENT OF WOUNDS AND ULCERS ........................... 73 D06 ANTIBIOTICS AND CHEMOTHERAPEUTICS FOR DERMATOLOGICAL USE ...... 73 D07 CORTICOSTEROIDS, DERMATOLOGICAL PREPARATIONS ................................... 75 D08 ANTISEPTICS AND DISINFECTANTS ........................................................................... 79 D10 ANTI-ACNE PREPARATIONS ......................................................................................... 79 D11 OTHER DERMATOLOGICAL PREPARATIONS ........................................................... 82 G GENITO URINARY SYSTEM AND SEX HORMONES ......................................................... 84 G01 GYNECOLOGICAL ANTIINFECTIVES AND ANTISEPTICS ...................................... 84 G02 OTHER GYNECOLOGICALS ........................................................................................... 85 G03 SEX HORMONES AND MODULATORS OF THE GENITAL SYSTEM ...................... 85 G04 UROLOGICALS ................................................................................................................. 87 H SYSTEMIC HORMONAL PREPARATIONS, EXCL. SEX HORMONES AND INSULINS 91 H01 PITUITARY AND HYPOTHALAMIC HORMONES AND ANALOGUES ................... 91 H02 CORTICOSTEROIDS FOR SYSTEMIC USE ................................................................... 91 H05 CALCIUM HOMEOSTASIS .............................................................................................. 92 J ANTIINFECTIVES FOR SYSTEMIC USE ................................................................................ 93 J01 ANTIBACTERIALS FOR SYSTEMIC USE ...................................................................... 93 J02 ANTIMYCOTICS FOR SYSTEMIC USE ........................................................................ 116 J05 ANTIVIRALS FOR SYSTEMIC USE ............................................................................... 119 vii L ANTINEOPLASTIC AND IMMUNOMODULATING AGENTS .......................................... 122 L01 ANTINEOPLASTIC AGENTS ......................................................................................... 122 L02 ENDOCRINE THERAPY ................................................................................................. 124 M MUSCULO-SKELETAL SYSTEM ......................................................................................... 128 M01 ANTIINFLAMMATORY AND ANTIRHEUMATIC PRODUCTS ............................... 128 M02 TOPICAL PRODUCTS FOR JOINT AND MUSCULAR PAIN .................................... 136 M03 MUSCLE RELAXANTS .................................................................................................. 138 M04 ANTIGOUT PREPARATIONS ....................................................................................... 138 M05 DRUGS FOR TREATMENT OF BONE DISEASES ..................................................... 139 N NERVOUS SYSTEM ................................................................................................................ 141 N01 ANESTHETICS................................................................................................................. 141 N02 ANALGESICS................................................................................................................... 141 N07 OTHER NERVOUS SYSTEM DRUGS ..........................................................................
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