PDF DRAFT Jan 2020

Drug Manufacturer Price Increases January 1, 2020-January 7, 2020 Brand Name Manufacturer Multi-Source/Single Source Brand/Generic Percent Change 1 ABRAXANE CELGENE Single Source Brand named 5 2 ACETYLCYSTEINE HOSPIRA/PFIZER Multiple Source Generically named 9.43 3 ACTEMRA GENENTECH INC. Single Source Brand named 3 4 ACTEMRA ACTPEN GENENTECH INC. Single Source Brand named 3 5 ACTHIB SANOFI-PASTEUR Multiple Source Brand named 4 6 ACTICLATE ALMIRALL LLC Multiple Source Brand named 5.37 7 ACTIQ TEVA USA Multiple Source Brand named 6.4 8 ACZONE ALLERG/ALMIRALL Multiple Source Brand named 8.22 9 ADACEL TDAP SANOFI-PASTEUR Single Source Brand named 3.01 10 ADDERALL TEVA USA Multiple Source Brand named 6.4 11 ADDYI SPROUT PHARMACE Single Source Brand named 9.38 12 ADVATE BAXALTA US INC. Multiple Source Brand named 3.05 13 ADYNOVATE BAXALTA US INC. Single Source Brand named 2.86 14 AEMCOLO ARIES/REDHILL B Single Source Brand named 9.07 15 ALECENSA GENENTECH INC. Single Source Brand named 3 16 ALINIA ROMARK LABORATO Single Source Brand named 9.01 17 ALPHAGAN P ALLERGAN INC. Multiple Source Brand named 5 18 ALPROLIX BIOVERATIV THER Single Source Brand named 3.85 19 ALTABAX ALMIRALL LLC Single Source Brand named 5 20 AMINOCAPROIC ACID HOSPIRA/PFIZER Multiple Source Generically named 9.3 21 AMINOPHYLLINE HOSPIRA/PFIZER Single Source Generically named 9.43 22 AMPICILLIN-SULBACTAM MYLAN INSTITUTI Multiple Source Generically named 10 23 AMRIX TEVA USA Multiple Source Brand named 6.4 24 ANALPRAM HC SEBELA PHARMACE Multiple Source Brand named 5.04 25 ANORO ELLIPTA GLAXOSMITHKLINE Single Source Brand named 3 26 ANTABUSE TEVA WOMEN'S HE Multiple Source Brand named 6.41 27 APTIOM SUNOVION PHARMA Single Source Brand named 4.9 28 APTIVUS BOEHRINGER ING. Single Source Brand named 6 29 ARIKAYCE INSMED INCORPOR Single Source Brand named 5.91 30 ARMOUR THYROID FOREST/ALLERGAN Multiple Source Brand named 5 31 ARNUITY ELLIPTA GLAXOSMITHKLINE Single Source Brand named 3 32 ATGAM PHARMACI/PFIZER Single Source Brand named 9.4 33 ATRIPLA GILEAD SCIENCES Single Source Brand named 4.8 34 ATROPINE SULFATE HOSPIRA/PFIZER Multiple Source Generically named 9.41 35 ATROVENT HFA BOEHRINGER ING. Single Source Brand named 6 36 AUSTEDO TEVA USA Single Source Brand named 5.9 37 AVONEX BIOGEN-IDEC Single Source Brand named 2 38 AVONEX PEN BIOGEN-IDEC Single Source Brand named 2 39 AYGESTIN TEVA WOMEN'S HE Multiple Source Brand named 6.38 40 AZELEX ALLERG/ALMIRALL Single Source Brand named 5 41 AZILECT TEVA NEUROSCIEN Multiple Source Brand named 6.4 42 BELBUCA BIODELIVERY SCI Single Source Brand named 5 43 BELEODAQ SPECTRUM/ACROTE Single Source Brand named 1.5 44 BENLYSTA GLAXOSMITHKLINE Single Source Brand named 1.5 45 BESPONSA WYETH/PFIZER Single Source Brand named 3 46 BETASERON BAYERPHARM DIV Multiple Source Brand named 4.6 47 BETHANECHOL CHLORIDE MAJOR PHARMACEU Multiple Source Generically named 24.22 48 BEXSERO GLAXOSMITHKLINE Single Source Brand named 5 49 BEYAZ BAYERPHARM DIV Multiple Source Brand named 5 50 BICILLIN C-R PFIZER US PHARM Single Source Brand named 9.4 51 BICILLIN L-A PFIZER US PHARM Single Source Brand named 9.4 52 BIDIL ARBOR PHARMACEU Single Source Brand named 5 53 BIKTARVY GILEAD SCIENCES Single Source Brand named 4.8 54 BLEPHAMIDE ALLERGAN INC. Single Source Brand named 5 55 BOOSTRIX TDAP GLAXOSMITHKLINE Single Source Brand named 3 56 BOSULIF PFIZER US PHARM Single Source Brand named 5 57 BRAFTOVI ARRAY BIOPHARMA Single Source Brand named 6 58 BREO ELLIPTA GLAXOSMITHKLINE Single Source Brand named 3 59 BRINEURA BIOMARIN PHARMA Single Source Brand named 2 60 BRISDELLE SEBELA PHARMACE Multiple Source Brand named 2.4 61 BRIVIACT UCB PHARMA Single Source Brand named 3 62 BROVANA SUNOVION PHARMA Single Source Brand named 4.2 63 BUNAVAIL BIODELIVERY SCI Single Source Brand named 5 64 BUPIVACAINE HCL-EPINEPHRINE HOSPIRA/PFIZER Multiple Source Generically named 9.51 65 BUTORPHANOL TARTRATE HOSPIRA/PFIZER Multiple Source Generically named 9.52 66 BUTRANS PURDUE PHARMA L Multiple Source Brand named 5 67 BYSTOLIC FOREST/ALLERGAN Single Source Brand named 5 68 CABOMETYX EXELIXIS INC. Single Source Brand named 5 69 CADUET PFIZER US PHARM Multiple Source Brand named 4.9 70 CALCIUM CHLORIDE HOSPIRA/PFIZER Multiple Source Generically named 9.38 71 CALDOLOR CUMBERLAND PHAR Single Source Brand named 7.97 72 CAMBIA ASSERTIO THERAP Single Source Brand named 9.9 73 CARAFATE APTALIS/ALLERGA Multiple Source Brand named 5 74 CARBAGLU ORPHAN EUROPE/R Single Source Brand named 3 75 CARDURA PFIZER US PHARM Multiple Source Brand named 4.9 76 CARDURA XL PFIZER US PHARM Single Source Brand named 4.9 77 CARNITOR LEADIANT BIOSCI Multiple Source Brand named 2.57 78 CARNITOR SF LEADIANT BIOSCI Multiple Source Brand named 2.56 79 CATAPRES-TTS 1 BOEHRINGER ING. Multiple Source Brand named 6 80 CATAPRES-TTS 2 BOEHRINGER ING. Multiple Source Brand named 6 81 CATAPRES-TTS 3 BOEHRINGER ING. Multiple Source Brand named 6 82 CAYSTON GILEAD SCIENCES Single Source Brand named 4.81 83 CEFAZOLIN SODIUM HOSPIRA/PFIZER Single Source Generically named 9.35 84 CEFTRIAXONE HOSPIRA/PFIZER Single Source Generically named 9.49 85 CELEBREX PFIZER US PHARM Multiple Source Brand named 4.9 86 CHANTIX PFIZER US PHARM Single Source Brand named 5 87 CHEMET RECORDATI RARE Single Source Brand named 8 88 CIMZIA UCB PHARMA Single Source Brand named 7 89 CINVANTI HERON THERAPEUT Single Source Brand named 2.25 90 CLIMARA BAYERPHARM DIV Multiple Source Brand named 5.01 91 CLIMARA PRO BAYERPHARM DIV Single Source Brand named 5 92 COAGADEX BIO PRODUCTS LA Single Source Brand named 5.03 93 COMBIGAN ALLERGAN INC. Single Source Brand named 5 94 COMBIPATCH NOVEN THERAPEUT Single Source Brand named 8.25 95 COMBIVENT RESPIMAT BOEHRINGER ING. Single Source Brand named 6 96 COMETRIQ EXELIXIS INC. Single Source Brand named 5 97 COMPLERA GILEAD SCIENCES Single Source Brand named 4.8 98 CORDRAN ALMIRALL LLC Multiple Source Brand named 5.37 99 CORLOPAM HOSPIRA/PFIZER Single Source Brand named 9.4 100 COSMEGEN RECORDATI RARE Multiple Source Brand named 10 101 COTEMPLA XR-ODT NEOS THERAPEUTI Single Source Brand named 13.24 102 CREON ABBVIE US LLC Single Source Brand named 7.4 103 CRYSVITA ULTRAGENYX PHAR Single Source Brand named 2.5 104 CUVITRU SHIRE/TAKEDA PH Single Source Brand named 2 105 CYSTADANE ORPHAN EUROPE/R Single Source Brand named 3 106 CYSTARAN LEADIANT BIOSCI Single Source Brand named 2.57 107 DALVANCE DURATA/ALLERGAN Single Source Brand named 3 108 DAPTACEL DTAP SANOFI-PASTEUR Single Source Brand named 3.01 109 DAURISMO PFIZER US PHARM Single Source Brand named 5 110 DAYTRANA NOVEN THERAPEUT Single Source Brand named 8.25 111 DEFINITY LANTHEUS MEDICA Single Source Brand named 5 112 DEMEROL HOSPIRA/PFIZER Single Source Brand named 9.41 113 DEPEN MEDA/MYLAN SPEC Single Source Brand named 6.5 114 DEPO-ESTRADIOL PHARMACI/PFIZER Single Source Brand named 9.4 115 DESCOVY GILEAD SCIENCES Single Source Brand named 4.8 116 DESONATE LEO PHARMA INC. Single Source Brand named 6 117 DESOXYN RECORDATI RARE Multiple Source Brand named 10 118 DEXTROSE IN WATER HOSPIRA/PFIZER Single Source Generically named 9.63 119 DIAZEPAM HOSPIRA/PFIZER Single Source Generically named 9.4 120 DILANTIN PFIZER US PHARM Multiple Source Brand named 4.9 121 DILANTIN-125 PFIZER US PHARM Multiple Source Brand named 4.9 122 DILTIAZEM HCL HOSPIRA/PFIZER Single Source Generically named 9.43 123 DIPHENHYDRAMINE HCL HOSPIRA/PFIZER Single Source Generically named 9.43 124 DIPHTHERIA-TETANUS TOXOIDS-PED SANOFI-PASTEUR Single Source Generically named 5.01 125 DONNATAL CONCORDIA PHARM Multiple Source Brand named 9.67 126 DOPAMINE HCL HOSPIRA/PFIZER Multiple Source Generically named 9.57 127 DOVATO VIIV HEALTHCARE Single Source Brand named 4.94 128 DOVONEX LEO PHARMA INC. Multiple Source Brand named 5 129 DOXYCYCLINE HYCLATE MYLAN INSTITUTI Multiple Source Generically named 9.89 130 DUAVEE WYETH/PFIZER Single Source Brand named 5 131 DYANAVEL XR TRIS PHARMA INC Single Source Brand named 9 132 DYMISTA MEDA/MYLAN SPEC Single Source Brand named 6.5 133 EDARBI ARBOR PHARMACEU Single Source Brand named 5 134 EDARBYCLOR ARBOR PHARMACEU Single Source Brand named 5 135 EFFEXOR XR WYETH/PFIZER Multiple Source Brand named 4.9 136 ELELYSO PFIZER US PHARM Single Source Brand named 3 137 ELESTRIN MEDA/MYLAN SPEC Single Source Brand named 6.5 138 ELIQUIS BMS PRIMARYCARE Single Source Brand named 6 139 ELOCTATE BIOVERATIV THER Single Source Brand named 2.76 140 EMFLAZA PTC THERAPEUTIC Single Source Brand named 9.1 141 EMPLICITI BMS PRIMARYCARE Single Source Brand named 1.5 142 EMSAM MYLAN SPECIALTY Single Source Brand named 6.5 143 ENDARI EMMAUS MEDICAL Single Source Brand named 3.96 144 ENGERIX-B ADULT GLAXOSMITHKLINE Single Source Brand named 5 145 ENGERIX-B PEDIATRIC-ADOLESCENT GLAXOSMITHKLINE Single Source Brand named 5.01 146 ENSTILAR LEO PHARMA INC. Single Source Brand named 6 147 EPANED SILVERGATE PHAR Single Source Brand named 9.15 148 EPINEPHRINE HOSPIRA/PFIZER Multiple Source Generically named 9.43 149 ERGOMAR TERSERA THERAPE Single Source Brand named 9 150 ERIVEDGE GENENTECH INC. Single Source Brand named 3 151 ERYTHROCIN LACTOBIONATE HOSPIRA/PFIZER Single Source Brand named 9.41 152 ESBRIET GENENTECH INC. Single Source Brand named 3 153 ESTRING PHARMACI/PFIZER Single Source Brand named 5 154 EUCRISA PFIZER US PHARM Single Source Brand named 3 155 EVEKEO ARBOR PHARMACEU Multiple Source Brand named 5 156 EVEKEO ODT ARBOR PHARMACEU Single Source Brand named 5 157 EXPAREL PACIRA PHARMACE Single Source Brand named 3 158 FANAPT VANDA PHARMACEU Single Source Brand named 8.01 159 FEIBA NF BAXALTA US INC. Single Source Brand named 3.11 160 FELBATOL MEDA/MYLAN SPEC Multiple Source Brand named 6.5 161 FEMRING MILLICENT PHARM Single Source Brand named 9.5 162 FENTANYL CITRATE HOSPIRA/PFIZER Multiple Source Generically named 9.68 163 FENTORA CEPHALONINC.-T Multiple Source Brand named 6.4 164 FERAHEME AMAG PHARMACEUT Single Source Brand named 4 165 FETZIMA FOREST/ALLERGAN Single Source Brand named 5 166 FINACEA LEO PHARMA INC. Multiple Source Brand named 5 167 FIORICET ACTAVIS/TEVA Multiple Source Brand named 6.41 168 FLOVENT DISKUS GLAXOSMITHKLINE Single Source Brand named 3 169 FLOVENT HFA GLAXOSMITHKLINE Single Source Brand named 3 170 FLUOROPLEX ALMIRALL LLC Single Source Brand named 5.37 171 FML ALLERGAN INC. Multiple Source Brand named 5 172 FML FORTE ALLERGAN INC. Single Source Brand named 5 173 FOLOTYN SPECTRUM/ACROTE Single Source Brand named 1 174 FUROSEMIDE HOSPIRA/PFIZER Single Source Generically named 9.39 175 GABITRIL CEPHALONINC.-T Multiple Source Brand named 6.42 176 GALZIN TEVA SELECT BRA Single Source Brand named 6.41 177 GAMASTAN GRIFOLS THERAPE Single Source Brand named 5 178 GAMASTAN S-D GRIFOLS THERAPE Single Source Brand named 5 179 GAMMAGARD S-D BAXALTA US INC. Single Source Brand named 1.5 180 GAMUNEX-C GRIFOLS THERAPE Multiple Source Brand named 2.5 181 GATTEX NPS PHARMACEUTI Single Source Brand named 3 182 GAZYVA GENENTECH INC. Single Source Brand named 1.5 183 GENOTROPIN PHARMACI/PFIZER Single Source Brand named 3 184 GENVOYA GILEAD SCIENCES Single Source Brand named 4.8 185 GEODON PFIZER US PHARM Multiple Source Brand named 4.9 186 GILOTRIF BOEHRINGER ING. Single Source Brand named 8 187 GLIADEL ARBOR PHARMACEU Single Source Brand named 2.5 188 GOCOVRI ADAMAS PHARMA Single Source Brand named 3.01 189 HAVRIX GLAXOSMITHKLINE Single Source Brand named 2.99 190 HEMLIBRA GENENTECH INC. Single Source Brand named 1 191 HEMOFIL M BAXALTA US INC. Single Source Brand named 2.9 192 HEPARIN SODIUM HOSPIRA/PFIZER Multiple Source Generically named 15.09 193 HEPARIN SODIUM IN 0.45% NACL HOSPIRA/PFIZER Single Source Generically named 15.06 194 HEPARIN SODIUM-0.9% NACL HOSPIRA/PFIZER Multiple Source Generically named 15.08 195 HEPARIN SODIUM-D5W HOSPIRA/PFIZER Multiple Source Generically named 15.03 196 HEPSERA GILEAD SCIENCES Multiple Source Brand named 4.8 197 HETLIOZ VANDA PHARMACEU Single Source Brand named 6 198 HIBERIX GLAXOSMITHKLINE Multiple Source Brand named 2.97 199 HIZENTRA CSL BEHRING LLC Single Source Brand named 2 200 HORIZANT XENOPORT/ARBOR Single Source Brand named 3.5 201 HUMIRA ABBVIE US LLC Single Source Brand named 7.4 202 HUMIRA PEDIATRIC CROHN'S ABBVIE US LLC Single Source Brand named 7.4 203 HUMIRA PEN ABBVIE US LLC Single Source Brand named 7.4 204 HUMIRA PEN CROHN'S-UC-HS ABBVIE US LLC Single Source Brand named 7.4 205 HUMIRA PEN PSOR-UVEITS-ADOL HS ABBVIE US LLC Single Source Brand named 7.4 206 HUMIRA(CF) ABBVIE US LLC Single Source Brand named 7.4 207 HUMIRA(CF) PEDIATRIC CROHN'S ABBVIE US LLC Single Source Brand named 7.4 208 HUMIRA(CF) PEN ABBVIE US LLC Single Source Brand named 7.4 209 HUMIRA(CF) PEN CROHN'S-UC-HS ABBVIE US LLC Single Source Brand named 7.4 210 HUMIRA(CF) PEN PSOR-UV-ADOL HS ABBVIE US LLC Single Source Brand named 7.4 211 HYDROMORPHONE HCL HOSPIRA/PFIZER Single Source Generically named 9.32 212 HYPERRAB GRIFOLS THERAPE Single Source Brand named 3.42 213 HYPERTET S-D GRIFOLS THERAPE Single Source Brand named 5 214 HYQVIA BAXALTA US INC. Single Source Brand named 2 215 HYSINGLA ER PURDUE PHARMA L Single Source Brand named 5 216 IBRANCE PFIZER US PHARM Single Source Brand named 5 217 IDHIFA CELGENE Single Source Brand named 5 218 IMBRUVICA PHARMACYCLICS Single Source Brand named 7.4 219 IMITREX GLAXOSMITHKLINE Multiple Source Brand named 3 220 IMOGAM RABIES-HT SANOFI-PASTEUR Multiple Source Brand named 5 221 IMOVAX RABIES VACCINE SANOFI-PASTEUR Single Source Brand named 5 222 IMURAN SEBELA PHARMACE Multiple Source Brand named 5 223 INCRELEX IPSEN BIOPHARMA Single Source Brand named 9.9 224 INCRUSE ELLIPTA GLAXOSMITHKLINE Single Source Brand named 3 225 INDOCIN EGALET/ZYLA LIF Single Source Brand named 9.9 226 INFANRIX DTAP GLAXOSMITHKLINE Single Source Brand named 2.98 227 INFED ALLERGAN INC. Single Source Brand named 5 228 INJECTAFER AMER. REGENT Single Source Brand named 3 229 INLYTA PFIZER US PHARM Single Source Brand named 5 230 INSPRA PFIZER US PHARM Multiple Source Brand named 4.9 231 INTRAROSA AMAG PHARMACEUT Single Source Brand named 5.1 232 INVELTYS KALA PHARMACEUT Single Source Brand named 9.9 233 IPOL SANOFI-PASTEUR Single Source Brand named 5 234 IXIARO VALNEVA Single Source Brand named 2.5 235 IXINITY APTEVO BIOTHERA Single Source Brand named 2.92 236 JARDIANCE BOEHRINGER ING. Single Source Brand named 6 237 JENTADUETO BOEHRINGER ING. Single Source Brand named 6 238 JENTADUETO XR BOEHRINGER ING. Single Source Brand named 6 239 JULUCA VIIV HEALTHCARE Single Source Brand named 4.94 240 JUXTAPID AEGERION PHARMA Single Source Brand named 9.94 241 KADCYLA GENENTECH INC. Single Source Brand named 3 242 KCENTRA CSL BEHRING LL Single Source Brand named 3.31 243 KEPIVANCE SOBI-SWEDISH OR Single Source Brand named 5.4 244 KEPPRA UCB PHARMA Multiple Source Brand named 3 245 KEPPRA XR UCB PHARMA Multiple Source Brand named 3 246 KEVEYIS STRONGBRIDGE US Single Source Brand named 9 247 KHAPZORY SPECTRUM/ACROTE Single Source Brand named 1 248 KINERET SOBI-SWEDISH OR Single Source Brand named 5.4 249 KINRIX GLAXOSMITHKLINE Single Source Brand named 2.99 250 KORLYM CORCEPT THERAPE Single Source Brand named 5.01 251 KRISTALOSE CUMBERLAND PHAR Multiple Source Brand named 5 252 KUVAN BIOMARIN PHARMA Single Source Brand named 4.81 253 LABETALOL HCL HOSPIRA/PFIZER Multiple Source Generically named 9.41 254 LAMICTAL GLAXOSMITHKLINE Multiple Source Brand named 3 255 LAMICTAL (BLUE) GLAXOSMITHKLINE Multiple Source Brand named 3 256 LAMICTAL (GREEN) GLAXOSMITHKLINE Multiple Source Brand named 3 257 LAMICTAL (ORANGE) GLAXOSMITHKLINE Multiple Source Brand named 3 258 LAMICTAL ODT GLAXOSMITHKLINE Multiple Source Brand named 3 259 LAMICTAL ODT (BLUE) GLAXOSMITHKLINE Multiple Source Brand named 3 260 LAMICTAL ODT (GREEN) GLAXOSMITHKLINE Multiple Source Brand named 3 261 LAMICTAL ODT (ORANGE) GLAXOSMITHKLINE Multiple Source Brand named 3 262 LAMICTAL XR GLAXOSMITHKLINE Multiple Source Brand named 3 263 LAMICTAL XR (BLUE) GLAXOSMITHKLINE Single Source Brand named 3 264 LAMICTAL XR (GREEN) GLAXOSMITHKLINE Single Source Brand named 3 265 LAMICTAL XR (ORANGE) GLAXOSMITHKLINE Single Source Brand named 3 266 LANOXIN CONCORDIA PHARM Multiple Source Brand named 9.47 267 LATUDA SUNOVION PHARMA Single Source Brand named 4.9 268 LEMTRADA GENZYME Single Source Brand named 2.9 269 LETAIRIS GILEAD SCIENCES Multiple Source Brand named 4.8 270 LEXAPRO FOREST/ALLERGAN Multiple Source Brand named 5 271 LIDOCAINE HCL HOSPIRA/PFIZER Single Source Generically named 9.47 272 LIDOCAINE HCL-EPINEPHRINE HOSPIRA/PFIZER Multiple Source Generically named 9.32 273 LILETTA ALLERGAN INC. Single Source Brand named 5 274 LINZESS ALLERGAN INC. Single Source Brand named 5 275 LIPITOR PFIZER US PHARM Multiple Source Brand named 4.9 276 LIVALO KOWA PHARMACEUT Single Source Brand named 5 277 LO LOESTRIN FE ACTAVIS/ALLERGA Single Source Brand named 5 278 LOESTRIN TEVA WOMEN'S HE Multiple Source Brand named 6.4 279 LOESTRIN FE TEVA WOMEN'S HE Multiple Source Brand named 6.4 280 LORAZEPAM HOSPIRA/PFIZER Single Source Generically named 9.48 281 LORBRENA PFIZER US PHARM Single Source Brand named 5 282 LOSEASONIQUE TEVA WOMEN'S HE Multiple Source Brand named 6.4 283 LOTRONEX SEBELA PHARMACE Multiple Source Brand named 5 284 LUMIGAN ALLERGAN INC. Single Source Brand named 5 285 LUMOXITI ASTRAZENECA Single Source Brand named 1.5 286 LUPANETA PACK ABBVIE US LLC Single Source Brand named 7.4 287 LUPRON DEPOT ABBVIE US LLC Single Source Brand named 7.4 288 LUPRON DEPOT-PED ABBVIE US LLC Single Source Brand named 7.4 289 LYRICA PFIZER US PHARM Multiple Source Brand named 4.9 290 LYRICA CR PFIZER US PHARM Single Source Brand named 4.9 291 MACI VERICEL CORPORA Single Source Brand named 4 292 MAGNESIUM SULFATE HOSPIRA/PFIZER Single Source Generically named 9.43 293 MARCAINE SPINAL HOSPIRA/PFIZER Multiple Source Brand named 9.09 294 MATULANE LEADIANT BIOSCI Single Source Brand named 2.57 295 MEKTOVI ARRAY BIOPHARMA Single Source Brand named 4 296 MENACTRA SANOFI-PASTEUR Single Source Brand named 4.99 297 MENVEO A-C-Y-W-135-DIP GLAXOSMITHKLINE Single Source Brand named 3 298 MEPSEVII ULTRAGENYX PHAR Single Source Brand named 2.51 299 MIACALCIN MYLAN INSTITUTI Single Source Brand named 6.5 300 MIDAZOLAM HCL HOSPIRA/PFIZER Multiple Source Generically named 9.57 301 MINIVELLE NOVEN THERAPEUT Multiple Source Brand named 8.25 302 MIRAPEX ER BOEHRINGER ING. Multiple Source Brand named 6 303 MIRCETTE TEVA WOMEN'S HE Multiple Source Brand named 6.4 304 MOBIC BOEHRINGER ING. Multiple Source Brand named 6 305 MONUROL ALLERGAN INC. Single Source Brand named 5 306 MORPHINE SULFATE HOSPIRA/PFIZER Single Source Generically named 9.57 307 MOTEGRITY SHIRE US INC. Single Source Brand named 3 308 MYALEPT AEGERION PHARMA Single Source Brand named 9.94 309 MYLOTARG WYETH/PFIZER Single Source Brand named 3 310 NAFTIN SEBELA PHARMACE Multiple Source Brand named 5 311 NAGLAZYME BIOMARIN PHARMA Single Source Brand named 1.98 312 NAMZARIC ALLERGAN INC. Single Source Brand named 5 313 NATAZIA BAYERPHARM DIV Single Source Brand named 5 314 NEOPROFEN RECORDATI RARE Multiple Source Brand named 10 315 NEUPRO UCB PHARMA Single Source Brand named 4.9 316 NEURONTIN PFIZER US PHARM Multiple Source Brand named 4.9 317 NICOTROL PHARMACI/PFIZER Single Source Brand named 5 318 NICOTROL NS PHARMACI/PFIZER Single Source Brand named 5 319 NITROSTAT PFIZER US PHARM Multiple Source Brand named 4.91 320 NORTHERA LUNDBECK INC. Single Source Brand named 7.9 321 NORVASC PFIZER US PHARM Multiple Source Brand named 4.9 322 NUCALA GLAXOSMITHKLINE Single Source Brand named 2.25 323 NUCYNTA COLLEGIUM PHARM Single Source Brand named 9.9 324 NUCYNTA ER COLLEGIUM PHARM Single Source Brand named 9.9 325 NUEDEXTA AVANIR PHARMACE Single Source Brand named 6.51 326 NUVIGIL CEPHALONINC.-T Multiple Source Brand named 6.4 327 ODEFSEY GILEAD SCIENCES Single Source Brand named 4.8 328 OFEV BOEHRINGER ING. Single Source Brand named 6 329 OFIRMEV MALLINCKRODT HO Single Source Brand named 9 330 OMECLAMOX-PAK CUMBERLAND PHAR Single Source Brand named 8 331 OMNARIS COVIS PHARMA Single Source Brand named 5 332 ONFI LUNDBECK INC. Multiple Source Brand named 9.5 333 ONIVYDE IPSEN BIOPHARMA Single Source Brand named 9.94 334 OPDIVO BMS PRIMARYCARE Single Source Brand named 1.5 335 ORENCIA BMS PRIMARYCARE Single Source Brand named 6 336 ORENCIA CLICKJECT BMS PRIMARYCARE Single Source Brand named 6 337 ORENITRAM ER UNITED THERAP Single Source Brand named 4.9 338 ORILISSA ABBVIE US LLC Single Source Brand named 7.4 339 OSPHENA SHIONOGI PHARMA Single Source Brand named 5 340 OTOVEL ARBOR PHARMACEU Multiple Source Brand named 5 341 OXAYDO EGALET/ZYLA LIF Single Source Brand named 9.9 342 OXERVATE DOMPE US INC Single Source Brand named 2.75 343 OXTELLAR XR SUPERNUS PHARMA Single Source Brand named 8 344 OXYCONTIN PURDUE PHARMA L Multiple Source Brand named 5 345 OXYMORPHONE HCL ER AMNEAL PHARMACE Single Source Generically named 15.9 346 PALYNZIQ BIOMARIN PHARMA Single Source Brand named 4.51 347 PANCURONIUM BROMIDE HOSPIRA/PFIZER Single Source Generically named 9.49 348 PANHEMATIN RECORDATI RARE Single Source Brand named 3 349 PEDIARIX GLAXOSMITHKLINE Single Source Brand named 5 350 PEGANONE RECORDATI RARE Single Source Brand named 8 351 PENTACEL SANOFI-PASTEUR Single Source Brand named 3.99 352 PERFOROMIST MYLAN SPECIALTY Single Source Brand named 2 353 PERJETA GENENTECH INC. Single Source Brand named 3 354 PERSERIS INDIVIOR INC. Single Source Brand named 5 355 PEXEVA SEBELA PHARMACE Single Source Brand named 5 356 PHOSLYRA FRESENIUS MEDIC Single Source Brand named 5 357 PLAQUENIL CONCORDIA PHARM Multiple Source Brand named 5.57 358 PLEGRIDY BIOGEN-IDEC Single Source Brand named 2 359 PLEGRIDY PEN BIOGEN-IDEC Single Source Brand named 2 360 POMALYST CELGENE Single Source Brand named 6 361 POTASSIUM CHLORIDE HOSPIRA/PFIZER Multiple Source Generically named 9.44 362 PRADAXA BOEHRINGER ING. Single Source Brand named 6 363 PRAMOSONE SEBELA PHARMACE Multiple Source Brand named 5 364 PRAXBIND BOEHRINGER ING. Single Source Brand named 8 365 PRED FORTE ALLERGAN INC. Multiple Source Brand named 5 366 PRED MILD ALLERGAN INC. Single Source Brand named 5 367 PRED-G ALLERGAN INC. Single Source Brand named 5 368 PREFEST TEVA WOMEN'S HE Single Source Brand named 6.4 369 PREMARIN WYETH/PFIZER Single Source Brand named 5 370 PREMPHASE WYETH/PFIZER Single Source Brand named 5 371 PREMPRO WYETH/PFIZER Single Source Brand named 5 372 PREVNAR 13 WYETH/PFIZER Single Source Brand named 6.9 373 PRIALT TERSERA THERAPE Single Source Brand named 3.52 374 PRILOSEC COVIS PHARMA Single Source Brand named 9 375 PRISTIQ WYETH/PFIZER Multiple Source Brand named 3 376 PROAIR HFA TEVA SPECIALTY Multiple Source Brand named 3 377 PROAIR RESPICLICK TEVA SPECIALTY Single Source Brand named 3 378 PROGLYCEM TEVA SPECIALTY Single Source Brand named 6.39 379 PROSTIN VR PEDIATRIC PHARMACI/PFIZER Single Source Brand named 9.04 380 PROTONIX WYETH/PFIZER Multiple Source Brand named 5 381 PROTOPIC LEO PHARMA INC. Multiple Source Brand named 5 382 PROVIGIL CEPHALONINC.-T Multiple Source Brand named 6.4 383 QBRELIS SILVERGATE PHAR Single Source Brand named 9.31 384 QBREXZA DERMIRA INC. Single Source Brand named 5 385 QNASL TEVA SPECIALTY Single Source Brand named 6.4 386 QNASL CHILDREN TEVA SPECIALTY Single Source Brand named 6.4 387 QUADRACEL DTAP-IPV SANOFI-PASTEUR Single Source Brand named 2.99 388 QUARTETTE TEVA WOMEN'S HE Multiple Source Brand named 6.4 389 QUILLICHEW ER TRIS PHARMA INC Single Source Brand named 6 390 QUILLIVANT XR TRIS PHARMA INC Single Source Brand named 9.9 391 QVAR REDIHALER TEVA SPECIALTY Single Source Brand named 6 392 R-GENE 10 PHARMACI/PFIZER Single Source Brand named 3.01 393 RABAVERT GLAXOSMITHKLINE Single Source Brand named 3 394 RANEXA GILEAD SCIENCES Multiple Source Brand named 4.8 395 RAPAMUNE WYETH/PFIZER Multiple Source Brand named 3 396 RECOMBINATE BAXALTA US INC. Single Source Brand named 3.05 397 RELPAX PFIZER US PHARM Multiple Source Brand named 4.9 398 RESTASIS ALLERGAN INC. Single Source Brand named 5 399 RESTASIS MULTIDOSE ALLERGAN INC. Single Source Brand named 5 400 REVATIO PFIZER US PHARM Multiple Source Brand named 4.9 401 REVCOVI LEADIANT BIOSCI Single Source Brand named 2.57 402 REVLIMID CELGENE Single Source Brand named 6 403 RIXUBIS BAXALTA US INC. Multiple Source Brand named 3.23 404 ROMIDEPSIN PFIZER US PHARM Multiple Source Generically named 9.4 405 ROTARIX GLAXOSMITHKLINE Single Source Brand named 3 406 RUCONEST PHARMING HEALTH Single Source Brand named 4.51 407 SABRIL LUNDBECK INC. Multiple Source Brand named 9.5 408 SAVELLA ALLERGAN INC. Single Source Brand named 5 409 SEASONIQUE TEVA WOMEN'S HE Multiple Source Brand named 6.4 410 SEREVENT DISKUS GLAXOSMITHKLINE Single Source Brand named 3 411 SERNIVO ENCORE DERMATOL Single Source Brand named 5 412 SHINGRIX GLAXOSMITHKLINE Single Source Brand named 5 413 SIKLOS MEDUNIK USA Single Source Brand named 5 414 SKYRIZI (2 SYRINGES) KIT ABBVIE US LLC Single Source Brand named 7.4 415 SODIUM CHLORIDE HOSPIRA/PFIZER Multiple Source Generically named 9.72 416 SOLU-CORTEF PFIZER US PHARM Single Source Brand named 9.4 417 SOMATULINE DEPOT IPSEN BIOPHARMA Single Source Brand named 9.92 418 SOMAVERT PHARMACI/PFIZER Single Source Brand named 3 419 SOTYLIZE ARBOR PHARMACEU Single Source Brand named 5 420 SPIRIVA BOEHRINGER ING. Single Source Brand named 6 421 SPIRIVA RESPIMAT BOEHRINGER ING. Single Source Brand named 6 422 SPRIX EGALET/ZYLA LIF Single Source Brand named 9.9 423 SPRYCEL BMS PRIMARYCARE Single Source Brand named 6 424 STIOLTO RESPIMAT BOEHRINGER ING. Single Source Brand named 6 425 STRIBILD GILEAD SCIENCES Single Source Brand named 4.8 426 STRIVERDI RESPIMAT BOEHRINGER ING. Single Source Brand named 6 427 SUBLOCADE INDIVIOR INC. Single Source Brand named 5 428 SUBOXONE INDIVIOR INC. Multiple Source Brand named 4.97 429 SUPREP BRAINTREE/SEBEL Single Source Brand named 5 430 SUTENT PFIZER US PHARM Single Source Brand named 5 431 SYMPAZAN AQUESTIVE THERA Single Source Brand named 5 432 SYMPROIC BIODELIVERY SCI Multiple Source Brand named 5 433 SYNAGIS MEDIMMUNE/ASTRA Single Source Brand named 5 434 SYNERCID PFIZER US PHARM Single Source Brand named 9.4 435 SYNJARDY BOEHRINGER ING. Single Source Brand named 6 436 SYNJARDY XR BOEHRINGER ING. Single Source Brand named 6 437 SYNRIBO CEPHALONINC.-T Single Source Brand named 6.4 438 SYNTHROID ABBVIE US LLC Multiple Source Brand named 4.91 439 TACLONEX LEO PHARMA INC. Multiple Source Brand named 5 440 TAKHZYRO DYAX CORP./SHIR Single Source Brand named 3 441 TALZENNA PFIZER US PHARM Single Source Brand named 5 442 TAYTULLA ALLERGAN INC. Single Source Brand named 5 443 TAZICEF HOSPIRA/PFIZER Single Source Brand named 9.37 444 TAZORAC ALLERG/ALMIRALL Multiple Source Brand named 5 445 TDVAX GRIFOLS THERAPE Single Source Generically named 3.03 446 TECENTRIQ GENENTECH INC. Single Source Brand named 2 447 TECFIDERA BIOGEN-IDEC Single Source Brand named 6 448 TEFLARO ALLERGAN INC. Single Source Brand named 5 449 TENIVAC SANOFI-PASTEUR Single Source Brand named 3 450 TIMOLOL MALEATE PACIFIC/GREENST Multiple Source Generically named 9.35 451 TIVICAY VIIV HEALTHCARE Single Source Brand named 4.94 452 TNKASE GENENTECH INC. Single Source Brand named 3 453 TOVIAZ PFIZER US PHARM Single Source Brand named 5 454 TRADJENTA BOEHRINGER ING. Single Source Brand named 6 455 TRANXENE T-TAB RECORDATI RARE Multiple Source Brand named 10 456 TRELEGY ELLIPTA GLAXOSMITHKLINE Single Source Brand named 5 457 TREXALL TEVA WOMEN'S HE Single Source Brand named 6.41 458 TRIUMEQ VIIV HEALTHCARE Single Source Brand named 4.94 459 TROKENDI XR SUPERNUS PHARMA Single Source Brand named 8 460 TRUMENBA WYETH/PFIZER Single Source Brand named 6.9 461 TRUVADA GILEAD SCIENCES Single Source Brand named 4.8 462 TUBERSOL SANOFI-PASTEUR Multiple Source Brand named 5 463 TUDORZA PRESSAIR CIRCASSIA PHARM Single Source Brand named 9.9 464 TWINRIX GLAXOSMITHKLINE Single Source Brand named 5 465 TYBOST GILEAD SCIENCES Single Source Brand named 4.8 466 TYMLOS RADIUS HEALTH Single Source Brand named 7.9 467 TYPHIM VI SANOFI-PASTEUR Single Source Brand named 5 468 TYSABRI BIOGEN-IDEC Single Source Brand named 3.5 469 TYVASO UNITED THERAP Single Source Brand named 4.9 470 TYVASO REFILL KIT UNITED THERAP Single Source Brand named 4.9 471 UNITUXIN UNITED THERAP Single Source Brand named 5.9 472 VALTREX GLAXOSMITHKLINE Multiple Source Brand named 3 473 VAPRISOL-5% DEXTROSE CUMBERLAND PHAR Single Source Brand named 8 474 VARUBI TERSERA THERAPE Single Source Brand named 5 475 VELPHORO FRESENIUS MEDIC Single Source Brand named 5 476 VELTIN ALMIRALL LLC Multiple Source Brand named 5 477 VEMLIDY GILEAD SCIENCES Single Source Brand named 4.8 478 VENCLEXTA ABBVIE US LLC Single Source Brand named 5.02 479 VENCLEXTA STARTING PACK ABBVIE US LLC Single Source Brand named 5 480 VERAPAMIL HCL HOSPIRA/PFIZER Multiple Source Generically named 9.41 481 VERDESO ALMIRALL LLC Single Source Brand named 5.37 482 VIAGRA PFIZER US PHARM Multiple Source Brand named 4.9 483 VIBATIV THERA/CUMBERLAN Single Source Brand named 2.5 484 VIBERZI ALLERGAN INC. Single Source Brand named 5 485 VIIBRYD ALLERGAN INC. Single Source Brand named 5 486 VIMIZIM BIOMARIN PHARMA Single Source Brand named 1.98 487 VIMPAT UCB PHARMA Single Source Brand named 3 488 VIREAD GILEAD SCIENCES Multiple Source Brand named 4.8 489 VIVLODEX EGALET/ZYLA LIF Single Source Brand named 9.9 490 VIZIMPRO PFIZER US PHARM Single Source Brand named 5 491 VRAYLAR ALLERGAN INC. Single Source Brand named 2 492 VYVANSE SHIRE US INC. Single Source Brand named 5 493 WATER HOSPIRA/PFIZER Single Source Generically named 9.32 494 XALATAN PHARMACI/PFIZER Multiple Source Brand named 4.9 495 XALKORI PFIZER US PHARM Single Source Brand named 5 496 XANAX PHARMACI/PFIZER Multiple Source Brand named 4.9 497 XANAX XR PHARMACI/PFIZER Multiple Source Brand named 4.9 498 XATMEP SILVERGATE PHAR Single Source Brand named 3 499 XELJANZ PFIZER US PHARM Single Source Brand named 4.9 500 XELJANZ XR PFIZER US PHARM Single Source Brand named 4.9 501 XENAZINE LUNDBECK INC. Multiple Source Brand named 9.5 502 XERMELO LEXICON PHARMAC Single Source Brand named 4.89 503 XHANCE OPTINOSE US IN Single Source Brand named 4.9 504 XOFIGO BAYERPHARM DIV Single Source Brand named 1 505 XOLAIR GENENTECH INC. Single Source Brand named 2 506 XOLEGEL ALMIRALL LLC Single Source Brand named 5.37 507 XTAMPZA ER COLLEGIUM PHARM Single Source Brand named 9.9 508 YASMIN 28 BAYERPHARM DIV Multiple Source Brand named 5 509 YAZ BAYERPHARM DIV Multiple Source Brand named 5 510 YERVOY BMS PRIMARYCARE Single Source Brand named 1.5 511 YF-VAX SANOFI-PASTEUR Single Source Brand named 5 512 YUPELRI MYLAN SPECIALTY Single Source Brand named 3.52 513 ZEJULA TESARO INC. Single Source Brand named 5 514 ZELNORM US WORLDMEDS/AL Single Source Brand named 5 515 ZENPEP ALLERGAN INC. Single Source Brand named 5 516 ZENZEDI ARBOR PHARMACEU Multiple Source Brand named 5 517 ZIAC TEVA WOMEN'S HE Multiple Source Brand named 6.4 518 ZIPSOR ASSERTIO THERAP Single Source Brand named 9.9 519 ZOLOFT PFIZER US PHARM Multiple Source Brand named 4.9 520 ZONEGRAN CONCORDIA PHARM Multiple Source Brand named 6.48 521 ZORVOLEX EGALET/ZYLA LIF Single Source Brand named 9.9 522 ZTLIDO SCILEX PHARMACE Single Source Brand named 5.79 523 ZUBSOLV OREXO US INC. Single Source Brand named 3 524 ZYDELIG GILEAD SCIENCES Single Source Brand named 4.8 Methodology:

P4AD analyzed the wholesale acquisition cost (WAC) data for the 1,521 unique National Drug Codes (NDC) that increased in price between January 1, 2020 and January 7, 2020. Among the 1,521 NDCs that increased in price, 524 were defined as distinct product hikes. Our methodology for defining a distinct product was consistent with the CMS Dashboard’s definition. We define a product as a grouping of NDCs having the same branded drug name and being sold by the same manufacturer. For example, if a drug had the same brand name but multiple NDCs for variations in strength or dosage, it was considered one price hike. But if multiple brand names exist for a drug with the same active ingredient and the products vary in concentration or route of administration, then it would be counted as multiple price hikes.

Any drug duplicate that exists in the list above is identical to how drugs are defined in the CMS dashboard and consistent with the independent drug compendia company, AnalySource.

Pricing and NDC data was drawn from AnalySource as published by First Databank. We use AnalySource’s variable definitions which can be found below.

WAC: Wholesale Acquisition Cost (WAC) as published by First Databank represents the manufacturer's published catalog or list price for a drug product to wholesalers as reported to First Databank by the manufacturer. WAC does not represent actual transaction prices and does not include prompt pay or other discounts, rebates or reductions in price.

Brand Name: Generally provides the name that appears on the package label provided by the manufacturer.

Brand/Generic (Generic Name Indicator): Specifies whether a product is a brand-named product or a generically named product, using the product name as the criteria. When discussing drug products with respect to their manufacturers, generically named drug products are products without a proprietary name. Typically in the United States, these products are named consistent with the United States Adopted Names (USAN)

Manufacturer (Labeler Name): Uniquely identify the product labeler (a manufacturer, distributor, or repackager).

Multi-Source/Single Source Indicator: Specifies whether a product’s clinical formulation (i.e., its particular active ingredient, dosage form, route of administration and strength) is only available from a single labeler or from multiple labelers.

NDC: An 11-character alphanumeric column that contains NDCs, HRIs, UPCs, and PINs which are the external identifiers representing drugs and health-related products.