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NCI/CTEP Simplified Disease Classification Short Abbreviations for the SDC 1.0 Terms, abstracted from the 29 December 2004 release with Mandated Codes for submission of Disease Terms to CTMS and CDUS, July 2007 for explanations and updates, consult the NCI/DCTD/CTEP website

²²² AIDS-related and Condition ²²² Endocrine ²²² Hematopoietic Neoplasm/ AIDS-related Malignancy and Condition, Misc Endocrine Neoplasm, Miscellaneous Leukemia, Miscellaneous 100 49 026 AIDS-related complications 100 14 709 Endocrine , NOS 100 24 312 Leukemia, NOS 100 25 280 Diffuse infiltrative lymphocytosis syndrome Adrenal Cancer Acute Lymphoblastic Leukemia 100 20 188 HIV test positive 100 01 327 Adrenocortical carcinoma, NOS 100 00 846 Acute lymphoblastic leukemia, NOS AIDS-related Human Papillomavirus Neuroendocrine Cancer 100 03 890 Precursor B-lymphoblastic leuk. (B-precur ALL) 100 63 001 AIDS-related HPV infections 100 07 276 tumor 100 54 569 Precursor T-lymphoblastic leuk. (T-cell ALL) 906 00 068 AIDS-related HPV-related cancer, NOS 100 33 630 Islet cell tumors of the Acute Myeloid Leukemia 100 65 860 AIDS-related 100 57 270 Neuroendocrine cancer, NOS 100 00 884 Acute myeloid leukemia, NOS 100 08 229 AIDS-related 100 34 876 Pheochromocytoma (adrenal) 100 01 019 Acute promyelocytic leukemia AIDS-related Kaposi Sarcoma 100 41 056 Small cell carcinoma (extrapulmonary) 100 66 353 Treatment-related acute myloid leukemia 100 23 290 AIDS-related Kaposi sarcoma Parathyroid Cancer Chronic Lymphoid Leukemia AIDS-related 100 33 965 Parathyroid cancer, NOS 100 01 415 Adult T-cell leukemia/lymphoma 906 00 076 AIDS-related Hodgkin lymphoma Thyroid Cancer 100 08 960 Chronic lymphocytic leukemia, NOS 906 00 308 AIDS-related Non-Hodgkin lymphoma 100 02 240 Anaplastic thyroid carcinoma 100 19 053 Hairy cell leukemia 906 00 080 AIDS-related primary CNS lymphoma 100 16 935 Follicular thyroid carcinoma 100 36 888 Prolymphocytic leukemia (B or T-cell) ²²² Bone Neoplasm 100 65 861 Hurthle cell neoplasm (thyroid) 100 65 862 T-cell large granular lymphocytic leukemia Bone Neoplasm, Miscellaneous 100 27 105 Medullary thyroid carcinoma Chronic Myeloproliferative Disease 100 53 650 Bone cancer, NOS 100 33 701 Papillary thyroid carcinoma 100 65 872 CEL / hypereosinophilic syndrome Chondrosarcoma 100 43 738 Thyroid cancer, NOS 100 09 013 CML - Philadelphia chromosome positive 100 08 737 Chondrosarcoma ²²² Gastrointestinal Neoplasm 100 28 537 Chronic idiopathic myelofibrosis Ewing Sarcoma Gastrointestinal Neoplasm, Miscellaneous 100 15 493 Essential thrombocythemia 100 15 563 Ewing sarcoma/Periph prim neuroectodermal 100 17 986 , NOS 100 36 061 Polycythemia vera Osteosarcoma Anal Cancer Myelodysplastic Syndrome 100 31 291 Osteosarcoma 100 02 126 Anal cancer, NOS 100 28 534 Myelodysplastic syndrome, NOS ²²² Eye Neoplasm 100 41 840 of the anus Myelodysplastic/Myeloproliferative Disease Malignant Eye Neoplasm, Miscellaneous 100 09 018 Chronic myelomonocytic leukemia 100 25 549 Malignant eye cancer, NOS 100 09 951 of the colon 100 23 249 Juvenile myelomonocytic leukemia ²²² 100 38 045 Adenocarcinoma of the rectum Hematopoietic Neoplasm/Lymphoma 100 38 918 Retinoblastoma 100 10 029 Colorectal cancer, NOS Lymphoma, Miscellaneous ²²² CNS Neoplasm (Primary Tumor) Gastroesophageal Cancer 100 25 316 Lymphoma, NOS CNS Neoplasm (Primary Tumor), Miscellaneous 100 30 139 Adenocarcinoma of the esophagus B-Cell Proliferations of Uncertain Malignant Potential 100 07 959 CNS primary tumor, NOS 100 66 354 Adenocarcinoma of the gastroesophageal junct 100 25 325 Lymphomatoid granulomatosis 100 35 054 Pineal parenchymal tumor 100 01 150 Adenocarcinoma of the stomach Hodgkin Lymphoma Astrocytoma, High Grade 100 30 157 , NOS 100 20 231 Hodgkin lymphoma nodular LP, NOS 100 17 760 Gastric cancer, NOS 100 02 224 Anaplastic astrocytoma 100 20 255 Hodgkin lymphoma, NOS 100 30 186 Squamous cell carcinoma of the esophagus 100 06 143 Diffuse brainstem glioma 906 00 328 Hodgkin lymphoma-like PTLD 100 18 337 Glioblastoma multiforme Liver and Hepatobiliary Cancer Non-Hodgkin Lymphoma 100 08 093 High-grade astrocytoma, NOS 100 04 669 Cholangiocarcino, intra/extrahepat ACA 100 65 863 ALCL, primary cutaneous type Astrocytoma, Low Grade 100 17 618 Gall bladder carcinoma (adenocarcinoma) 100 65 864 ALCL, primary systemic type 100 19 822 100 65 889 Fibrillary astrocytoma 100 06 597 /leukemia 100 49 010 100 03 571 Low-grade astrocytoma, NOS 100 28 500 Cutaneous T-cell lymphoma/Mycosis fungoides 100 19 810 Liver and hepatobiliary cancer, NOS 906 00 112 Pilocytic astrocytoma 100 11 677 Cutaneous T-cell lymphoma/Sezary syndrome (excluding Islets) Plexus Tumors 100 12 820 Diffuse large B-cell lymphoma 100 52 747 Adenocarcinoma of the pancreas 100 65 855 Extranodal NK/T-cell lymphoma, nasal type 906 00 120 Choroid plexus carcinoma 100 65 908 of the pancreas 100 15 822 Extranodal marg. zone B-cell MALT-lymphoma Embryonal Tumors of the CNS 100 33 612 Pancreatic cancer (excluding Islets), NOS 100 16 896 Follicular lymphoma 100 65 870 Atypical teratoid/rhabdoid tumor Cancer 100 47 803 Lymphoplasmacytic lymphoma (Waldenstrom) 100 27 107 Medulloblastoma 100 41 115 Adenocarcinoma of the small intestine 100 26 799 Mantle cell lymphoma 100 56 672 Supratentorial primitive neuroectodermal tumor 100 54 184 Small intestine cancer, NOS 100 36 712 Mediastinal (thymic) large B-cell lymphoma Ependymal Tumors ²²² 100 29 462 Nodal marginal zone B-cell lymphoma 100 14 967 Ependymoma, NOS Germ Cell Neoplasm 100 29 593 Non-Hodgkin lymphoma, NOS Germ Cell Tumors of the CNS Germ Cell Neoplasm, Miscellaneous 100 18 204 Germ cell cancer, NOS 100 63 908 Non-Hodgkin lymphoma, aggressive, NOS 100 65 852 of CNS 100 65 856 Non-Hodgkin lymphoma, indolent, NOS 100 65 853 Nongerminomatous of the CNS Extragonadal Germ Cell Cancer (*qualified) 100 15 790 Extragonadal germ cell tumors, NOS 906 00 336 PTLD (Monoclonal), NOS Meningeal Tumors 906 00 340 PTLD (Polyclonal), NOS 100 27 189 Meningioma, NOS Ovarian Germ Cell Cancer 100 52 759 Ovarian 100 34 624 Peripheral T-cell lymphoma, NOS Oligodendroglial Tumors 100 36 525 Precursor B-lymphoblastic lymphoma 100 26 659 Anaplastic oligodendroglioma 100 52 311 Ovarian nondysgerm. germ cell tumor, NOS Testicular Germ Cell Cancer 100 36 545 Precursor T-lymphoblastic lymphoma 100 30 286 Oligodendroglioma, NOS 100 07 953 Primary CNS lymphoma 100 43 321 Testicular nonseminomat germ cell tumor, NOS Tumors of the Sellar Region 100 65 857 Primary effusion lymphoma 100 43 353 Testicular seminoma 100 11 318 Craniopharyngioma 100 03 910 Small lymphocytic lymphoma, NOS 100 35 106 Pituitary gland cancer, NOS

²²² Hematopoietic Neoplasm/Myeloma ²²² , Mediastinal and Pleural Neoplasm ²²² Nervous System Neoplasm & Disorder, excl CNS Myeloma Lung, Mediastinal and Pleural Neoplasm, Misc CNS-excluded Nervous System Neoplasm, Misc 100 28 566 Myeloma, NOS 100 25 065 , NOS 100 29 208 CNS-excluded nervous system cancer, NOS 100 20 631 Monoclonal gammopathy of undet signif (MGUS) Mediastinal Cancer Neuroblastoma 100 35 484 Solitary plasmacytoma 100 43 673 Thymoma 100 29 261 Neuroblastoma ²²² Hematopoietic Neoplasm, excl Leuk,Lymph,Myelom Mesothelioma Neurofibromatosis Hematopoietic Neoplasm, Miscellaneous 100 27 410 Mesothelioma 100 29 268 Neurofibromatosis 100 18 864 Hematopoietic malignancy, NOS Non-Small Cell Lung Cancer ²²² Skin Neoplasm 100 25 581 Langerhans cell histiocytosis 100 58 354 Bronchioloalveolar carcinoma Skin Neoplasm, Miscellaneous Mastocytosis 906 00 324 Lung ACA w/ bronchioloalveolar features 100 40 811 Skin cancer, NOS 100 25 638 Systemic mastocytosis, NOS 100 25 032 Lung adenocarcinoma Basal Cell Carcinoma ²²² Head and Neck Neoplasm 100 29 514 Non-small cell lung cancer, NOS 100 04 146 Basal cell carcinoma Head and Neck Neoplasm, Miscellaneous 100 25 126 Squamous cell lung carcinoma 100 25 960 , NOS Small Cell Lung Cancer 100 53 571 Melanoma Head and Neck 100 41 071 Small cell lung cancer Merkel Cell Tumor 906 00 168 Head and neck precancerous condition ²²² Reproductive System Neoplasm, Female 100 29 266 Merkel cell tumor Head and Neck Squamous Cell Carcinoma Female Reproductive System Neoplasm, Misc Squamous Cell Carcinoma of the Skin 100 60 121 Head and neck squamous cell carcinoma, NOS 100 16 411 Female reproductive system cancer, NOS 100 41 834 Squamous cell carcinoma of the skin 100 23 843 Laryngeal squamous cell carcinoma Cervical Cancer ²²² Soft Tissue Neoplasm 100 24 534 Lip and oral cavity squamous cell carcinoma 100 08 238 Cervical cancer, NOS Soft Tissue Neoplasm, Miscellaneous 100 34 819 Pharyngeal squamous cell carcinoma 100 08 224 Adenocarcinoma of the cervix 100 61 271 Soft tissue neoplasm, NOS Nasopharyngeal Cancer 100 41 848 Squamous cervical cancer Non- Soft Tissue Sarcoma 100 28 786 Cervical Intraepithelial Neoplasia (CIN) 100 01 886 Alveolar soft part sarcoma Salivary Gland Cancer 100 59 383 Cervical intraepithelial neoplasia (CIN) 100 65 865 CCS (excl CCS kidney) 100 39 397 Salivary gland cancer Gestational Trophoblastic Disease 100 57 043 Dermatofibrosarcoma ²²² Breast Neoplasm 100 18 212 Gestational trophoblastic disease 100 64 587 Desmoplastic small round cell tumor Breast Neoplasm, Miscellaneous , excl Ovarian Germ Cell Cancer 100 16 637 Fibrosarcoma (excluding infantile) 100 06 285 , NOS 100 16 180 Fallopian tube carcinoma 100 51 066 Gastrointestinal stromal tumor Breast Cancer - In situ 100 33 272 Ovarian cancer, NOS 100 65 859 Infantile fibrosarcoma (congenital) 100 13 806 Ductal carcinoma in situ 100 33 159 Ovarian epithelial cancer 100 24 193 (excl uterine leiomyosarcoma) 100 24 744 Lobular carcinoma in situ 100 65 858 Ovarian stromal cancer 100 24 631 Liposarcoma Breast Cancer - Invasive 100 33 268 Ovarian tumors of low malignant potential 100 25 556 Malignant fibrous histiocytoma 100 53 130 Cystosarcoma phylloides of the breast 100 26 669 Primary peritoneal carcinoma 100 26 667 Malignant peripheral nerve sheath tumor 100 21 980 Inflammatory breast carcinoma 100 39 494 Non-Rhabdomyo soft tissue sarcoma, NOS 100 06 190 Invasive breast carcinoma 100 07 508 Carcinosarcoma of the uterus 100 65 866 Plexiform neurofibroma ²²² Immune Disorder (excl AIDS and malignancy) 100 48 397 Endometrial stromal sarcoma 100 42 866 Synovial sarcoma Immune Disorder (excl AIDS & malignancy), Misc 100 14 735 Endometrioid endometrial adenocarcinoma Rhabdomyosarcoma 100 46 799 Leiomyosarcoma of the uterus 100 21 425 Immune disorder, NOS 100 65 867 Alveolar rhabdomyosarcoma 100 33 700 Serous endometrial adenocarcinoma 100 02 024 Amyloidosis 100 65 868 Embryonal rhabdomyosarcoma 100 46 804 Uterine cancer, NOS 100 00 802 Graft versus host disease, acute 100 39 024 Rhabdomyosarcoma, NOS 100 08 907 Graft versus host disease, chronic Vaginal Cancer ²²² Miscellaneous Neoplasm Immunodeficiency and Immunosuppression Disorder 100 46 888 Vaginal cancer, NOS Miscellaneous Neoplasm 100 21 510 Immunosuppression disorders Vaginal Intraepithelial Neoplasia (VIN) 100 25 691 Miscellaneous neoplasm, NOS 900 02 028 Lymphoadenopathy w/ polyclonal hypergamma 100 46 890 Vaginal intraepithelial neoplasia (VIN) Carcinoma, Miscellaneous 100 35 755 Lymphocytic interstitial pneumonitis 100 01 166 Adenocarcinoma, NOS ²²² Kidney Neoplasm 100 47 743 Vulvar cancer, NOS 100 07 423 Carcinoma, NOS ²²² Kidney Neoplasm, Miscellaneous Reproductive System Neoplasm, Male Metastases, Distant (excl specified site of origin) 100 38 485 Kidney cancer, NOS Male Reproductive System Neoplasm, Misc 100 24 233 Leptomeningeal metastases, NOS Clear Cell Sarcoma of the Kidney 100 25 519 Male reproductive system cancer, NOS 100 25 538 Malignant ascites, NOS 100 09 253 Clear cell sarcoma of the kidney 100 27 452 Metastases to bone, NOS Renal Cell Carcinoma 906 00 236 Penile adenocarcinoma 100 59 282 Metastases to brain parenchyma, NOS 100 66 351 Collecting duct renal cancer 100 34 330 Penile cancer, NOS 100 27 457 Metastases to liver, NOS 100 33 702 Papillary renal cell carcinoma 100 59 631 Penile squamous carcinoma (epidermoid) 100 27 458 Metastases to lung, NOS 100 09 251 Renal cell carcinoma, clear cell adenocarcinoma Prostate Cancer 100 51 676 Metastases to , NOS 100 66 352 Renal cell carcinoma with sarcomatoid features 100 36 910 Prostate cancer, NOS 100 27 465 Metastases to skin, NOS 100 38 415 Renal cell carcinoma, NOS Prostatic Intraepithelial Neoplasia (PIN) 100 26 673 Pleural effusion, NOS Rhabdoid Tumor of the Kidney 100 36 912 Prostate intraepithelial neoplasia (PIN) Solid Tumor, Miscellaneous 100 39 019 Rhabdoid tumor of the kidney Testicular Cancer, excl Testicular Germ Cell Cancer 100 29 000 Solid tumor, NOS Wilms Tumor 100 43 342 Testicular cancer, not germ cell/trophoblast Vascular Tumor, Miscellaneous 100 29 145 Wilms tumor (Nephroblastoma) ²²² Urothelial Tract Neoplasm 100 55 031 Vascular tumor, NOS Urothelial Tract/Bladder Neoplasm, Misc ²²² Non-neoplastic Disorder 100 18 192 Urothelial tract/bladder cancer, NOS Non-neoplastic Disorder, Miscellaneous Urothelial Tract/Bladder Cancer 906 00 296 Non-neoplastic disorder, NOS 100 44 409 Transitional cell carcinoma of the urothelial tract

Note: NCI/CTEP anticipates revising the CDUS submission codes effective July 1 every year.

This July 2007 version of the “SDC1 list” was composed by Theradex, copyright  2007 all rights reserved. CN 5257, Princeton, NJ USA tel. 609-799-7580 fax. 609-799-4148 www.Theradex.com

Theradex operates CTMS , the Clinical Trials Monitoring Service, on behalf of NCI/DCTD/CTEP