DOCSLIB.ORG

Prostate Massage Apparatus

Total Page：16

File Type：pdf, Size：1020Kb

Download full-text PDF Read full-text
Prostate Massage Apparatus (19) & (11) EP 2 098 209 A1 (12) EUROPEAN PATENT APPLICATION (43) Date of publication: (51) Int Cl.: 09.09.2009 Bulletin 2009/37 A61H 21/00 (2006.01) A61H 39/04 (2006.01) (21) Application number: 09153839.7 (22) Date of filing: 27.02.2009 (84) Designated Contracting States: (71) Applicant: Takashima, Jiro AT BE BG CH CY CZ DE DK EE ES FI FR GB GR Houston, TX 77055 (US) HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO SE SI SK TR (72) Inventor: Takashima, Jiro Designated Extension States: Houston, TX 77055 (US) AL BA RS (74) Representative: Giovannini, Francesca et al (30) Priority: 03.03.2008 US 41501 Osha Liang 32, avenue de l’Opéra 75002 Paris (FR) (54) Prostate massage apparatus (57) An apparatus for massaging a prostate includes ually reducing diameters distal to the head portion; and a body having a substantially ellipsoid shape and sized a retainer bar joined the body at one end of the neck to fit in a rectum through a sphincter, wherein the body portion to form a substantially T-shaped structure, where- comprises a head portion and a neck portion, wherein in the retainer bar comprises two contact points for con- the head portion is configured to contact the prostate tacting a first acupressure point, which is located in the through the rectum wall when inserted in the rectum, and perineum region between the anus and the scrotum, and wherein the neck portion has a tapered section with grad- a second acupressure point, which is located about mid- way between the anus and the lower end of the coccyx. EP 2 098 209 A1 Printed by Jouve, 75001 PARIS (FR) 1 EP 2 098 209 A1 2 Description [0007] U.S. Patent No. 2,478,786, issued to H. M. Smallen, describes a prostate gland massaging imple- BACKGROUND OF INVENTION ment that is operated by hand. This implement includes a lever having an interior handle which constitutes a pow- Field of the Invention 5 er arm to extend down in front of the abdomen and a substantially horizontal portion extending under the groin [0001] The present invention relates to apparatus for and offset laterally to avoid the genital organs. The im- preventing and treating prostate abnormalities, including plement has an upwardly and forwardly bent posterior benign prostate hyperplasia (BPH) and prostatitis. More portion which forms the work arm. This work arm extends particularly, the present invention relates to devices for 10 into the rectal passage to bear against the frontal wall massaging the prostate gland. thereof adjacent the prostate gland. The bent portion be- tween the horizontal and the posterior portions serves Background Art as a fulcrum point against the front wall of the rectal open- ing when the implement is subject to pivotal movement [0002] Prostate is a compound tubuloalveolar exocrine 15 around this point. glad that is part of the male reproduction system in mam- [0008] The inventor of the present application has in- mals. Common prostate abnormalities include benign vented several prostate massaging devices, as disclosed prostate hyperplasia (BPH), prostatitis, and prostate can- in U.S. Patent Nos. 5,797,950; 5,861,000; 6,589,193; cer. BPH is a condition with enlarged prostate gland, of- 6,802,850; and 7,211,059; and published U.S. Patent Ap- ten occurs in older men. Severe BPH can cause urination 20 plication Nos. 2002/0040200; 2004/0158182; and difficulties due to the enlarged prostate pressing against 2005/0266048. These devices are operated by the con- the urethra. BPH can be treated with medication or with traction of the sphincter muscles, without the need of surgery that removes part of the prostate. hand operations. FIGs. 1 and 2 illustrate two of such de- [0003] Prostatitis is inflammation of the prostate gland. vices. There are different forms of prostatitis. Acute prostatitis 25 [0009] As shown in FIG. 1, a device for prostate mas- and chronic bacterial prostatitis may be treated with an- sage has a generally rod-shape body comprising a head tibiotics, while chronic non-bacterial prostatitis, which ac- portion 112 designed to contact the prostate through the counts for about 95% of prostatitis diagnoses, may be rectum, a neck portion 123, and a retainer portion 114. treated with a variety of modalities, including α-adrener- The neck portion 123, having gradually reducing diame- gic blockers, physical therapy, psychotherapy, and anti- 30 ters from the head portion 112, is designed to allow con- histamines. traction of the sphincter muscle to push the device up- [0004] Chronic non-bacterial prostatitis may lead to flu- ward to massage the prostate. The retainer portion 114, id build up in the prostate, resulting in a congested pros- which joins the neck portion 123 at the bend 121 to form tate. One treatment for chronic non-bacterial prostatitis a generally C-shape, is designed to prevent the device is the prostate massage. Some urologists believe that 35 from completely slipping into the rectum and also to con- the most effective treatment for such prostatitis is for the tact the perineum-groin area, thereby forcing the head doctor to massage the prostate at regular intervals. How- portion 112 to contact the prostate. ever, such massages can be difficult to obtain because [0010] FIGs. 2A and 2B show another prostate mas- it often requires frequent visits by the patients to doctor’s saging device invented by the present inventor, illustrat- offices, which is associated with considerable expense 40 ing the location of the device in the rectum 24 before and inconvenience. Therefore, there is a need for devices (FIG. 2A) and after (FIG. 2B) sphincter muscle 26 con- that would allow an individual to carry out his own pros- traction. As the device is pushed up by the sphincter 26 tatic massage. contraction, the head portion 42 presses against the [0005] Since prostate is located proximate the anus, prostate 28, as shown in FIG. 2B. When the sphincter various devices that can contact prostate gland through 45 muscles 26 relax, the device will slide downward, result- rectal wall have been devised in the art. For example, ing in less compression of the prostate, as shown in FIG. U.S. Patent No. 4,542,753, issued to Brenman et al., dis- 2A. Therefore, repeated contraction and relaxation of the closes an apparatus having electrodes and circuitry for sphincter muscles can produce the desired massage of generating electrical signals to stimulate prostate gland the prostate without using a hand. and erectile tissue, after the device is disposed in the 50 [0011] These prior art devices provide convenient rectum. ways to massage a congested prostate. [0006] U.S. Patent No. 5,404,881, issued to Cathaud However, there remains a need for improved prostate et al., describes a trans-rectal probe made of a flexible massage devices. self-supporting polymer material. The flexibility of the pol- ymer material enables it to comply with the shape therein, 55 SUMMARY OF INVENTION making it possible to achieve safe and reliable positioning of an instrument for detection or therapeutic treatment of [0012] One aspect of the invention relates to apparatus an organ (such as prostate) through the rectum. for massaging a prostate. An apparatus in accordance 2 3 EP 2 098 209 A1 4 with one embodiment of the invention includes a body to the retainer bar and the body portion flexibly jointed having a substantially ellipsoid shape and sized to fit in with the retainer bar. a rectum through a sphincter, wherein the body compris- [0023] FIG. 7 shows several variations and modifica- es a head portion and a neck portion, wherein the head tions of the prostate massaging apparatus in accordance portion is configured to contact the prostate through the 5 with embodiments of the invention, illustrating various rectum wall when inserted in the rectum, and wherein shapes of the bodies and retainer bars that may be used the neck portion has a tapered section with gradually with embodiments of the invention. reducing diameters distal to the head portion; and a re- [0024] FIG. 8 shows an illustration of a sectional view tainer bar joined the body at one end of the neck portion of a lower portion of a human body, illustrating the loca- to form a substantially T-shaped structure, wherein the 10 tions of the two acupressure points. retainer bar comprises two contact points for contacting [0025] FIG. 9 shows a diagram illustrating a prostate a first acupressure point, which is located in the perineum massaging apparatus in use. region between the anus and the scrotum, and a second acupressure point, which is located about midway be- DETAILED DESCRIPTION tween the anus and the lower end of the coccyx, wherein 15 the head portion and the two contact points are config- [0026] Embodiments of the invention relates to pros- ured such that they can contact the prostate, the first tate massage apparatus that rely on sphincter muscles acupressure point, and the second acupressure point si- to provide the massage action, i.e., converting the multaneously. sphincter’s contraction and relaxation actions to an up- [0013] Another aspect of the invention relates to meth- 20 and-down motion of the device in the rectum to massage ods for massaging a prostate. A method in accordance the prostate. In addition, the apparatus in accordance with one embodiment of the invention includes providing with embodiments of the invention can provide pressure a device configured to contact the prostate, a first acu- in the perineum region and a region midway between the pressure point located in the perineum region between anus and the lower end of the coccyx (tail bone) to pro- the anus and the scrotum, and a second acupressure 25 duce acupressure therapeutic effects to stimulate these point located about midway between the anus and the areas for therapeutic purposes.
Load more

Recommended publications
  • Prostatitis Explained Prostatitis
    Prostate information Prostatitis Explained Prostatitis Prostatitis (prost-a-ty-tus) is the most common prostate problem for men under 50, but it can affect men of all ages. In fact, almost 1 out of 2 men between 18 and 50 may have at least one bout of prostatitis in their lifetime. Prostatitis is often described as an infection of the prostate but it can also mean that the prostate is inflammed or irritated. If you have prostatitis, you may have a burning feeling when passing urine, pass urine more often, be in a lot of pain, have a fever and chills and feel very tired. Once your doctor has diagnosed your symptoms as prostatitis, then the outlook tends to be good. There are many treatments available and your doctor will work with you to find the treatment(s) most suitable for you depending on the type of prostatitis you have. So, it may take slightly longer for some men to see an improvement in their symptoms. However, even when you feel your symptoms are starting to improve you should still continue with your treatment or medication. It may be reassuring to know that prostatitis is neither connected with cancer nor does it mean there is an increased risk of developing prostate cancer in the future, but it can cause worrying symptoms. Table of contents Page Types of prostatitis 3 Acute bacterial prostatitis 5 Chronic bacterial prostatitis 8 Chronic pelvic pain syndrome 9 Treatment for CBP and CPPS 13 Coping with pain 14 Tips to relieve prostatitis 16 Prostatitis There are different types of prostatitis.
    [Show full text]
  • The Fine Art of Prostate Massage
    The Fine Art of Prostate Massage Part I: What exactly are we dealing with here? Or, Anatomy, 101 • What is the prostate gland? Very simply, it is the part of the male body that store and secretes an essential part of semen. More specifically, the prostate gland produces an alkaline fluid that makes up about 30% of the semen. The alkalinity, interestingly, helps offset female vaginal acidity. • Where is the prostate gland? The prostate is located in lower abdominal area, roughly between the bladder and the rectal wall (which makes it easy to feel and to play with). Notice that one part of the prostate (shown in green) runs along the wall near the rectal area. This is the part that we are interested in. The prostate is slightly larger than a walnut, which can make both exams and play a bit challenging. Anatomy is highly variable, which means we have to be patient. • Do biological females have a prostate gland? Not in the same way that a biological male does. There is a small gland, also called the Skene’s Gland or the paraurethural gland. While it is homologous to the male prostate, it serves a slightly different purpose. An authoritative medical group officially called the female prostate such in 2002, and it is thus “officially” known as a prostate. It does play an active role during the female orgasm. The female prostate is located in approximately the same place as the male prostate. The anatomy here, though, is also highly variable. It may play a significant part in female “ejaculation”.
    [Show full text]
  • 2002 Asa Program.Pdf
    schedule at a lance Wednesday, April 24, 2002 • Genetics and Biology of Adult Male Germ Cell 8:00 am Andrology Laboratory Workshop Tumors The Andrology Laboratory of the Future: Raju S.K. Chaganti, Memoria l Sloan-Kettering Impact of the Genomic and Proteomic • Modeling Human Disease Through Transgenesis Revolutions (concludes at 5:00 pm) Sarah Comerford, UTSWMS & HHI • How to Find Cellular Proteins that Sense the 5:30 pm Welcome and Opening Remarks Environment Da vid Garbers, HHM/ 5:45 pm Distinguished Andrologist Award 6:00 pm Serano Lecture 12:00 pm Laboratory Science Lunch • Of Genes and Genomes 1:30 pm Symposium Ill: Do Gene Defects Impact Da vid Botstein, Stanford University Male Reproduction: If So, How? •The Battle of the Sexes: Sry and the Control of Testis 7:15 pm Welcome Reception Organogenesis Blanche Capel, Duke Univ. Med. Ctr. Thursday, April 25, 2002 • Natural Potent Androgens: Lessons from Human Genetic Models 8:00 am Solvay/Unimed Lecture J. /mperato-McGinley, Cornell University •Androgen Therapy in the Older Man-Where • Genetic Defects in Male Reproduction Are We Now and Where Are We Going? Stephanie Seminara, Harvard University Lisa Te nover, Emory University 3:00 pm Refreshment Break and Exhibits 8:55 am Distinguished Service Award 3:15 pm Plenary Lecture 9:05 am Biopore Lecture • The Ins & Outs of PSMA, the Evolving and • Global Analysis of Germline Gene Expression Intriguing Tale of its Prostate Biology & Tumor Sam Wa rd, University of Arizona Targeting WO. Heston, Cleveland Clinic 10:00 am Coffee Break and Exhibits 4:05 pm Schering Lecture 10:30 am Concurrent Oral Sessions I, II, Ill • Bioethics and Stem Cell Research • Basic and Clinical Aspects of Male Sexual Laurie Zoloff, San Fra ncisco State Univ.
    [Show full text]
  • Andrological Sciences Official Journal of the Italian Society of Andrology
    Vol. 17 • No. 2 • June 2010 Journal of ANDROLOGICAL SCIENCES Official Journal of the Italian Society of Andrology Cited in Past Editors Editorial Board Fabrizio Menchini Fabris (Pisa) Antonio Aversa (Roma) SCOPUS Elsevier Database 1994-2004 Ciro Basile Fasolo (Pisa) Carlo Bettocchi (Bari) Edoardo Pescatori (Modena) Guglielmo Bonanni (Padova) Paolo Turchi (Pisa) Massimo Capone (Gorizia) 2005-2008 Tommasi Cai (Firenze) Luca Carmignani (Milano) Antonio Casarico (Genova) Editors-in-Chief Carlo Ceruti (Torino) Vincenzo Ficarra (Padova) Fulvio Colombo (Milano) Andrea Salonia (Milano) Luigi Cormio (Foggia) Federico Dehò (Milano) Giorgio Franco (Roma) Editor Assistant Andrea Galosi (Ancona) Ferdinando Fusco (Napoli) Giulio Garaffa (London) Andrea Garolla (Padova) Paolo Gontero (Torino) Managing Editor Vincenzo Gulino (Roma) Vincenzo Gentile (Roma) Massimo Iafrate (Padova) Copyright Sandro La Vignera (Catamia) SIAS S.r.l. • via Luigi Bellotti Bon, 10 Francesco Lanzafame (Catania) 00197 Roma Delegate of Executive Committee Giovanni Liguori (Trieste) of SIA Mario Mancini (Milano) Editorial Office Giuseppe La Pera (Roma) Alessandro Mofferdin (Modena) Lucia Castelli (Editorial Assistant) Nicola Mondaini (Firenze) Tel. 050 3130224 • Fax 050 3130300 Giacomo Novara (Padova) [email protected] Section Editor – Psychology Enzo Palminteri (Arezzo) Pacini Editore S.p.A. • Via A. Gherardesca 1 Annamaria Abbona (Torino) Furio Pirozzi Farina (Sassari) 56121 Ospedaletto (Pisa), Italy Giorgio Pomara (Pisa) Marco Rossato (Padova) Publisher Statistical Consultant Paolo Rossi (Pisa) Pacini Editore S.p.A. Elena Ricci (Milano) Antonino Saccà (Milano) Via A. Gherardesca 1, Gianfranco Savoca (Palermo) 56121 Ospedaletto (Pisa), Italy Omidreza Sedigh (Torino) Tel. 050 313011 • Fax 050 3130300 Marcello Soli (Bologna) [email protected] Paolo Verze (Napoli) www.pacinimedicina.it Alessandro Zucchi (Perugia) www.andrologiaitaliana.it INDEX Journal of Andrological Sciences EDITORIAL PCA3 a promising urine biomarker for prostate cancer diagnosis V.
    [Show full text]
  • Specific Antigen Level and Serum Fasting Glucose, Total Cholesterol
    Original Article DO I: 10.4274/uob.999 Bulletin of Urooncology 2018;17:59-62 Assessment of the Relationship Between Serum Prostate- Specific Antigen Level and Serum Fasting Glucose, Total Cholesterol and Neutrophil-Lymphocyte Ratio in Men Aged 50-70 Years with Prostate-Specific Antigen Level 0-10 ng/mL without Prostate Cancer Diagnosis Bora İrer MD İzmir Metropolitan Municipality Eşrefpaşa Hospital, Clinic of Urology, İzmir, Turkey Abstract Objective: To evaluate the relationship between serum prostate-specific antigen (PSA) level and total cholesterol, fasting blood glucose, and neutrophil- lymphocyte ratio (NLR) in men without prostate cancer. Materials and Methods: Between 2010 and 2017, 2631 male participants aged 50-70 years with a serum PSA level of 0-10 ng/mL were included from a population of 4643 healthy males who participated in a health screening program conducted by the İzmir Metropolitan Municipality Eşrefpaşa Hospital in the district villages of İzmir. Participants’ serum PSA, fasting blood glucose, total cholesterol levels, and NLR were retrospectively assessed. Participants were grouped as those with high and low serum PSA levels, high and low glucose levels, and high and low cholesterol levels. Differences between the groups in terms of serum PSA levels, serum total cholesterol, glucose, and NLR were analyzed. Results: The mean age of the participants was 60.2±5.4 years and the mean serum PSA level was 1.28±1.20 ng/mL. The mean PSA value was higher in the high cholesterol group (1.36±1.33 vs 1.19±1.02, p<0.001) compared to the low cholesterol group, and the mean PSA value in the high glucose group was lower than in the low glucose group (1.08±0.86 vs 1.32±1.25, p<0.001).
    [Show full text]
  • Narrative Review of Urinary Glycan Biomarkers in Prostate Cancer
    1864 Review Article on Urinary Biomarkers of Urological Malignancies Narrative review of urinary glycan biomarkers in prostate cancer Shingo Hatakeyama1^, Tohru Yoneyama2^, Yuki Tobisawa3^, Hayato Yamamoto3, Chikara Ohyama1,2,3^ 1Department of Advanced Blood Purification Therapy, Hirosaki University Graduate School of Medicine, Hirosaki, Japan; 2Department of Glycotechnology, Center for Advanced Medical Research, Hirosaki University Graduate School of Medicine, Hirosaki, Japan; 3Department of Urology, Hirosaki University Graduate School of Medicine, Hirosaki, Japan Contributions: (I) Conception and design: S Hatakeyama; (II) Administrative support: None; (III) Provision of study materials or patients: None; (IV) Collection and assembly of data: All authors; (V) Data analysis and interpretation: All authors; (VI) Manuscript writing: All authors; (VII) Final approval of manuscript: All authors. Correspondence to: Shingo Hatakeyama, MD. Department of Urology, Hirosaki University Graduate School of Medicine, 5 Zaifu-cho, Hirosaki 036- 8562, Japan. Email: [email protected]. Abstract: Prostate cancer (PC) is the second most common cancer in men worldwide. The application of the prostate-specific antigen (PSA) test has improved the diagnosis and treatment of PC. However, the PSA test has become associated with overdiagnosis and overtreatment. Therefore, there is an unmet need for novel diagnostic, prognostic, and predictive biomarkers of PC. Urinary glycoproteins and exosomes are a potential source of PC glycan biomarkers. Urinary glycan profiling can provide noninvasive monitoring of tumor heterogeneity and aggressiveness throughout a treatment course. However, urinary glycan profiling is not popular due to technical disadvantages, such as complicated structural analysis that requires specialized expertise. The technological development of glycan analysis is a rapidly advancing field. A lectin-based microarray can detect aberrant glycoproteins in urine, including PSA glycoforms and exosomes.
    [Show full text]
  • Controversies in Using Urine Samples for Prostate Cancer Detection: PSA and PCA3 Expression Analysis
    Clinical Urology Prostate Cancer detection International Braz J Urol Vol. 37 (6): 719-726, November - December, 2011 Controversies in using urine samples for Prostate Cancer detection: PSA and PCA3 expression analysis S. Fontenete, J. Silva, A.L. Teixeira, R. Ribeiro, E. Bastos, F. Pina, R. Medeiros Molecular Oncology Group and Virology LB (SF, JS, ALT, RR, RM), Portuguese Institute of Oncol- ogy of Porto; ICBAS, Abel Salazar Institute for the Biomedical Sciences (SF, JS, ALT, RR, RM), University of Porto; Research Department - Portuguese League Against Cancer (NRN) (JS, ALT, RR, RM), Porto; Centre of Genetics and Biotechnology (EB), University of Trás-os-Montes and Alto Douro; Department of Urology (FP), S. João Hospital, University of Porto Medical School; CE- BIMED, Faculty of Health Sciences of Fernando Pessoa University (RM), Porto, Portugal ABSTRACT Purpose: Prostate cancer (PCa) is one of the most commonly diagnosed malignancies in the world. Although PSA utili- zation as a serum marker has improved prostate cancer detection it still presents some limitations, mainly regarding its specificity. The expression of this marker, along with the detection of PCA3 mRNA in urine samples, has been suggested as a new approach for PCa detection. The goal of this work was to evaluate the efficacy of the urinary detection of PCA3 mRNA and PSA mRNA without performing the somewhat embarrassing prostate massage. It was also intended to opti- mize and implement a methodological protocol for this kind of sampling. Materials and Methods: Urine samples from 57 patients with suspected prostate disease were collected, without under- going prostate massage. Increased serum PSA levels were confirmed by medical records review.
    [Show full text]
  • Heteronormativity and Homophobia In
    View metadata, citation and similar papers at core.ac.uk brought to you by CORE provided by University of Oregon Scholars' Bank POWER AND PLEASURE: HETERONORMATIVITY AND HOMOPHOBIA IN HETEROSEXUAL SEX by LAUREN STEWART A DISSERTATION Presented to the Department of Sociology and the Graduate School of the University of Oregon in partial fulfillment of the requirements for the degree of Doctor of Philosophy June 2018 DISSERTATION APPROVAL PAGE Student: Lauren Stewart Title: Power and Pleasure: Heteronormativity and Homophobia in Heterosexual Sex This dissertation has been accepted and approved in partial fulfillment of the requirements for Doctor of Philosophy degree in the Department of Sociology by: Jocelyn Hollander Co-Chair CJ Pascoe Co-Chair Eileen Otis Core Member Yvonne Braun Institutional Representative and Sara D. Hodges Interim Vice Provost and Dean of the Graduate School Original approval signatures are on file with the University of Oregon Graduate School. Degree awarded June 2018. ii © 2018 Lauren Stewart DISSERTATION ABSTRACT Lauren Stewart iii Doctor of Philosophy Department of Sociology June 2018 Title: Power and Pleasure: Heteronormativity and Homophobia in Heterosexual Sex How do sex practices get constructed as normal? This research evaluates discussions of pegging, a gender non-conforming sex practice within heterosexual sex whereby women anally penetrate men. Data were collected from the website Reddit and its subreddit r/sex. 3,485 comments posted to 30 discussion threads were analyzed for common themes. Findings suggest that pegging confuses gendered expectations for “having sex”. Additionally, heteronormativity and homophobia were found to structure heterosexual interactions, including the ways in which gender and sexual identities, desire, and bodies are understood.
    [Show full text]
  • Prostate 1 Prostate
    Prostate 1 Prostate Prostate Male Anatomy Prostate with seminal vesicles and seminal ducts, viewed from in front and above. Latin prostata [1] Gray's subject #263 1251 Artery internal pudendal artery, inferior vesical artery, and middle rectal artery Vein prostatic venous plexus, pudendal plexus, vesicle plexus, internal iliac vein Nerve inferior hypogastric plexus Lymph external iliac lymph nodes, internal iliac lymph nodes, sacral lymph nodes Precursor Endodermic evaginations of the urethra [2] MeSH Prostate [3] Dorlands/Elsevier Prostate The prostate (from Greek προστάτης - prostates, literally "one who stands before", "protector", "guardian"[4] ) is a compound tubuloalveolar exocrine gland of the male reproductive system in most mammals unless they have it removed at birth.[5] [6] In 2002, female paraurethral glands, or Skene's glands, were officially renamed the female prostate by the Federative International Committee on Anatomical Terminology.[7] The prostate differs considerably among species anatomically, chemically, and physiologically. Prostate 2 Function The function of the prostate is to store and secrete a slightly alkaline fluid, milky or white in appearance,[8] that usually constitutes 20-30% of the volume of the semen along with spermatozoa and seminal vesicle fluid. The alkalinity of semen helps neutralize the acidity of the vaginal tract, prolonging the lifespan of sperm. The alkalinization of semen is primarily accomplished through secretion from the seminal vesicles.[9] The prostatic fluid is expelled in the first ejaculate fractions, together with most of the spermatozoa. In comparison with the few spermatozoa expelled together with mainly seminal vesicular fluid, those expelled in prostatic fluid have better motility, longer survival and better protection of the genetic material (DNA).
    [Show full text]
  • Prostate Massage Apparatus Prostatamassagevorrichtung Appareil De Massage De La Prostate
    (19) & (11) EP 2 098 209 B1 (12) EUROPEAN PATENT SPECIFICATION (45) Date of publication and mention (51) Int Cl.: of the grant of the patent: A61H 21/00 (2006.01) A61H 39/04 (2006.01) 26.10.2011 Bulletin 2011/43 (21) Application number: 09153839.7 (22) Date of filing: 27.02.2009 (54) Prostate massage apparatus Prostatamassagevorrichtung Appareil de massage de la prostate (84) Designated Contracting States: (72) Inventor: Takashima, Jiro AT BE BG CH CY CZ DE DK EE ES FI FR GB GR Houston, TX 77055 (US) HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO SE SI SK TR (74) Representative: Giovannini, Francesca et al Osha Liang (30) Priority: 03.03.2008 US 41501 32, avenue de l’Opéra 75002 Paris (FR) (43) Date of publication of application: 09.09.2009 Bulletin 2009/37 (56) References cited: WO-A-2007/012792 US-A- 5 797 950 (73) Proprietor: Takashima, Jiro Houston, TX 77055 (US) Note: Within nine months of the publication of the mention of the grant of the European patent in the European Patent Bulletin, any person may give notice to the European Patent Office of opposition to that patent, in accordance with the Implementing Regulations. Notice of opposition shall not be deemed to have been filed until the opposition fee has been paid. (Art. 99(1) European Patent Convention). EP 2 098 209 B1 Printed by Jouve, 75001 PARIS (FR) 1 EP 2 098 209 B1 2 Description [0007] U.S. Patent No. 2,478,786, issued to H.
    [Show full text]
  • Prostatitis T I N Daniel A
    C Diagnosis and Management of O N Acute and Chronic Prostatitis T I N Daniel A. Shoskes Floyd Katske U Sun Kim I N G rostatitis syndromes pre- Prostatitis syndromes are some of the most poorly understood yet sent an interesting con- prevalent problems in urology. There is little controversy over acute trast in incidence and prostatitis, a urinary tract infection with systemic symptoms and E understanding. Acute and signs that typically responds to antimicrobial therapy. By contrast, D Pchronic bacterial prostatitis are the chronic prostatitis syndromes have so far eluded attempts to relatively uncommon, but well- U understand their pathophysiology and design effective therapies, C understood urinary tract infec- resulting in great frustration among patients and health care tions caused by established providers. An accurate diagnosis and a multidisciplinary approach A uropathogens. They are typically T responsive to appropriate antimi- are essential to assist men with this often debilitating condition. crobial therapy. By contrast, the I much more common nonbacteri- O Objectives al prostatitis and prostatodynia N syndromes remain an enigma, This educational activity is designed for nurses and other health both in etiology, appropriate care professionals who care for and educate patients regarding acute workup, and therapy. The rough- and chronic prostatitis. The multiple choice examination that follows ly 2 million annual outpatient is designed to test your achievement of the following educational objec- visits for chronic prostatitis in tives. After studying this offering, you will be able to: the United States (Collins, 1. Define acute and chronic prostatitis. Stafford, O’Leary, & Barry, 1998) 2. Discuss the diagnosis of acute and chronic prostatitis.
    [Show full text]
  • Advances and Perspectives in Prostate Cancer Biomarker Discovery in the Last 5 Years Through Tissue and Urine Metabolomics
    H OH metabolites OH Review Advances and Perspectives in Prostate Cancer Biomarker Discovery in the Last 5 Years through Tissue and Urine Metabolomics Ana Rita Lima 1,* , Joana Pinto 1 , Filipa Amaro 1, Maria de Lourdes Bastos 1,Márcia Carvalho 1,2,3,* and Paula Guedes de Pinho 1,* 1 UCIBIO/REQUIMTE, Laboratory of Toxicology, Department of Biological Sciences, Faculty of Pharmacy, University of Porto, Rua Jorge Viterbo Ferreira, 228, 4050-313 Porto, Portugal; [email protected] (J.P.); [email protected] (F.A.); [email protected] (M.d.L.B.) 2 UFP Energy, Environment and Health Research Unit (FP-ENAS), University Fernando Pessoa, Praça Nove de Abril, 349, 4249-004 Porto, Portugal 3 Faculty of Health Sciences, University Fernando Pessoa, Rua Carlos da Maia, 296, 4200-150 Porto, Portugal * Correspondence: [email protected] (A.R.L.); [email protected] (M.C.); [email protected] (P.G.d.P.); Tel.: +351-220-428-500 (A.R.L. & P.G.d.P.); +351-225-071-300 (M.C.) Abstract: Prostate cancer (PCa) is the second most diagnosed cancer in men worldwide. For its screening, serum prostate specific antigen (PSA) test has been largely performed over the past decade, despite its lack of accuracy and inability to distinguish indolent from aggressive disease. Metabolomics has been widely applied in cancer biomarker discovery due to the well-known metabolic reprogramming characteristic of cancer cells. Most of the metabolomic studies have Citation: Lima, A.R.; Pinto, J.; reported alterations in urine of PCa patients due its noninvasive collection, but the analysis of prostate Amaro, F.; Bastos, M.d.L.; Carvalho, tissue metabolome is an ideal approach to disclose specific modifications in PCa development.
    [Show full text]