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Clinical Evaluation of Eladi Churna & Yavadi Kwath in Amlapitta

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Clinical Evaluation of Eladi Churna & Yavadi Kwath in Amlapitta INTERNATIONAL AYURVEDIC MEDICAL JOURNAL International Ayurvedic Medical Journal, (ISSN: 2320 5091) (June, 2017) 5(6) CLINICAL EVALUATION OF ELADI CHURNA & YAVADI KWATH IN AMLAPITTA Garima Raj1, O.P.Dadhich2, C.R.Yadav3 1MD Scholar, 2Associate Professor, HOD & Dean Academic, 3Assistant Professor PG. Dept of Sharir Kriya, Natinal Institute of Ayurveda, Jaipur, Rajasthan, India Email: [email protected] ABSTRACT Acharya Charak has not mentioned Amlapitta as separate disease entity like Kashyap & Madhav. The Samprapti of Grahani Rog mentioned by Acharya Charak is able to explain the pathogenesis; he mentiones that Ajirn, Atimatra, Vishama, Astamya, Veg Dharan etc leads to vitiation of Agni, due to which one cannot digest even Laghu Anna. This undigested food becomes sour in taste & which works like poison. This form of Annavisha when associated with Pitta causes Daha, Trishna, & Mukha Rog. It also causes Amlapitta & such other Paittik Vyadhi1. Many conditions in Modern Sci- ence included under the broad umbrella of Amlapitta. Though the conventional methods being used have only symptomatic relief, no curative effect is provided, along with many adverse effects. Antac- ids are the one of the most widely used medicine all over the world. Food and drug Administration (FDA) warned that there is increase risk of fractures with the use of Proton Pump Inhibitor. By tak- ing antacids the person neutralizes acid which is the first line of immunity and becomes more prone to various infections. The drug selected under the study Eladi Churna & Yavadi Kwath described in Yogratnakara Amlapitta Chikitsa, possesses properties which helps to pacify Tridosha, does Ama Pachan which provides a better approach of treatment2. Keywords: Amlapitta, Acid peptic disease, Eladi Churna, Yavadi Kwath. INTRODUCTION “AMLAYA PITTAM AMLAPITTAM” ferent functions like; Rag (Ranjan of Rakta (Vachaspati) Dhatu), Pakti (Pachan), Tej (Drishti), Medha It means Pitta leading to sour taste is called as (intelligence), Ushma (maintenance of tem- Amlapitta. It is composed of word Amla & perature)3. Though, Amla Rasa has been men- Pitta. Pitta is a Dosha which is present in the tioned as a natural property of Pitta along with body at five different places & does five dif- Katu Rasa according to Acharya Charak. Garima Raj Et Al: Clinical Evaluation Of Eladi Churna & Yavadi Kwath In Amlapitta Acharya Sushrut has enlisted Katu as its origi- Vyakta Sthana - Uraha, Kantha, nal Rasa and mentioned that when Pitta be- Amashaya etc. comes Vidagdh then it changes into Amla Adhishthana – Amashaya. Rasa. Its Nidan can be divided into Aharaj, Rogamarga – Abhyantara. Viharaj, Manasik & Agantuj Hetu. Symptoms Rupa – Chirakari. of Ajirna and specially Vidagdhajirna appear- ing before the manifestation of disease may be No specific disease is seen similar to considered as its Purvarupa. In Charaka Amlapitta in Modern medicine. The signs and Samhita while describing the Samprapati of symptoms of Amlapitta disease are given in Grahani, Acharya indicates Amlapitta also. modern medicine under title of Acid peptic Various symptoms are mentioned by different disease. There are number of disease in acid Acharya which can be mentioned as Avipak, peptic diseases like – Acute gastritis, chronic Klama, Utklesha, Amla Udgara, Hrit-Kantha gastritis, peptic ulcers, gastro oesophageal re- 4 Daha, Gaurav & Aruchi . Various types of flux diseases, non ulcer dyspepsia, hyper- Amlapitta can be explained on different classi- chlorhydria syndrome, menetrier's disease etc. fication basis i.e. on the basis of vitiated Peptic ulcers (gastric and duodenal ulcers) 5 Dosha, on the basis of Sthan Dushti of Srotas . have similar symptoms related to Amlapitta. According to Acharya Kashayp, Nidana Sevan But the pathophysiology and histopathology causes Dosha Prakopa especially of Pitta said that ulcer's can't be included in Amlapitta. Dosha. This Dosha Prakopa leads to It may be included in complications of Mandagni due to which ingested food Amlapitta. becomes Vidagdh and attains Shuktibhava In treatment of Amlapitta, Vaman & Virechan which further manifest Amlata in Amashaya. Karma are mentioned but both these Karma 6 This condition is called Amlapitta . are contra indicated in ulcers. Therefore we can't include peptic ulcers in Amlapitta. So, Amlapitta Samprapti Ghatak: the Acid peptic disease without peptic ulcer Dosha – Pitta Pradhan, Samana Vayu & can be included in Amlapitta. For the purpose Kledaka Kapha. of getting clinical co-relation and similarily Dushya – Rasa. between Amlapitta and non-ulcerative acid Agni – Jathragni Mandhya. peptic disease. Ama - Jathragni Mandhyajanya Ama. Srotas – Annavaha, Rasavaha, Raktavaha GASTRO-OESOPHAGEAL REFLUX & Purishavaha Srotas. DISEASE:- It refers to the various clinical manifestations Srotodushti – Atipravritti & Vimarg of reflux of stomach & duodenal contents in to Gaman. the oesophagus. Although, it may associate Udhbhava – Amashaya & Pittadhara with the sliding hiatus hernia. Kala. Sanchara Sthana – Sarva Shareera. IAMJ: JUNE, 2017 1857 Garima Raj Et Al: Clinical Evaluation Of Eladi Churna & Yavadi Kwath In Amlapitta ACUTE GASTRITIS:- quality of life and sometime though it is not The term acute gastritis is usually acute ero- life hindering but still it affects ones day to sive conditions that typically result in necrosis day life. Many studies have been done in this and haemorrhage of the mucosa with relative context but still it is a common prevalent prob- inflammation. It may however, be completely lem. asymptomatic. Its course is self-limiting and healing usually occurs without any residual MATERIAL AND METHODS damage. Criteria for Assessment of Amlapitta (a)Subjective parameters—grading was done DYSPEPSIA (NON-ULCERATIVE) on the basis of signs and symptoms mentioned Dyspepsia (Indigestion) is a term for non- in Ayurvedic texts & trial drug was assessed specific symptoms thought to originate from on that basis. the upper gastrointestinal tract. Typical symp- (b)Objective parameters— Routine blood toms include upper abdominal discomfort examination— Hb%, TRBC, TLC, DLC. For with/without related to food, anorexia, nausea, assessment of result statistically suitable test vomiting, bloating & heartburn. were applied. Criteria for Selection of Patients— MANAGEMENT:- The diagnosis was done on the basis of clinical (1) Managed by relieving the causative fac- signs and symptoms mentioned in Ayurvedic tors. classics and also based on special proforma. (2) Drugs:- Antacids METHODS OF COLLECTION OF DATA H-2 antagonists / proton pump Inhibitors. 1. Study Design—A simple random two Prokinetic & anticholinergics. group observational study for 30 days. Antibiotics which relieve the infections 2. Sample Size— The study was done in 30 like H-pylori. patients with 15 patients in two groups for the (3) Supportive therapy:- clinical trial. Loading dose of Vit - B12 Protein supplements. CLINICAL STUDY Patients suffering from Amlapitta and consent- Intravenous fluid therapy. (4) Surgical treatment in some cases is no sub- ing to participate in drug trial was selected from OPD of NIA hospital, Jaipur. stance in the world that does not have thera- peutic utility. ALLOCATION OF GROUP Patients were randomly selected in two groups NEED OF STUDY A & B with 15 patients in each group. Due to urbanization, changed lifestyle and die- tary incompatibility Amlapitta has became a common problem in the society. It affects the IAMJ: JUNE, 2017 1858 Garima Raj Et Al: Clinical Evaluation Of Eladi Churna & Yavadi Kwath In Amlapitta Group A was given Eladi Churna, 3 gms 2. Non-compliance of treatment regimen. twice a day, before meal for 30 days with two 3. Adverse drug reactions of the trial drugs. follow up. Group B was given Yavadi Kwath, 40ml twice ROUTINE EXAMINATION AND a day, after meal for 30 days with two follow ASSESSMENT up. Complete detailed history and physical exami- nation of patients was recorded as per the Pro- INCLUSION CRITERIA forma. Clinical and physiological assessment 1. Classical symptoms of Amlapitta. was done before and after treatment. 2. Patients of either sex and between 16-60 years of age. Pathya-Apathya 3. Patients willing and able to carry out All the patients were strictly kept on specifi- treatment for 30 days. cally prescribed diet and were instructed to 4. Patients were registered with duly signed avoid the causes of Amlapitta, as per the clas- informed consent prior to the trial. sics. 5. Chronicity less than 1 year. Diet EXCLUSION CRITERIA Usually the patient himself follows the dietary 1. Patients with diagnosed cases of gastric, instructions, however, they were advised to peptic and duodenal ulcers. follow the Ashtavidha Aaharvidhi Vishesha- 2. Patients with any GIT, abdominal compli- yatan and restrict the use of Amla, Katu and cations and chronic illness. Lavan Rasa, Ushn and Tikshn Guna diet due 3. Patients with diagnosed cases of any sys- to their provocative nature. temic and structural disorder. 4. Pregnant and lactating women. Follow-up Follow-up was done on 15 days, 2 follow up WITHDRAWAL CRITERIA was done. 1. Any major disease necessary for starting new treatment modality. SCORING PATTERN Table1: AVIPAK Consumption of meal in good quantity 2-3 times. 0 Consumption of meal in moderate quantity 2 times a day. 1 Consumption of meal in less quantity 2 times a day. 2 Consumption of meal in less quantity once a day. 3 Not taking food. 4 IAMJ: JUNE, 2017 1859 Garima Raj Et Al: Clinical Evaluation Of Eladi Churna & Yavadi Kwath In Amlapitta Tablel 2: KLAMA No Klama 0 Occasional feeling of Klama (lassitude) without Shrama and remains for some time. 1 Klama without Shrama daily for some time. 2 Klama without Shrama daily for long duration. 3 Table 3: UTKLESH No Utklesh. 0 Utklesh occurs occasionally 2-3 times in a week. 1 Utklesh occurs daily but not severe. 2 Utklesh subsides after Langhana. 3 Severe degree of Utklesh not relieved by any Upakrama. 4 Table 4: AMLA UDGARA No Amla Udgara. 0 Occasionally during day or night for less than ½ hr. after meals. 1 Amla Udgara occurs daily for 2 to 3 times for ½-1 hr. 2 Amla Udgara after every intake of meal or any food substance for ½-1 hr.
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