ENSA monoclonal antibody (M02), clone 1H7

Catalog # : H00002029-M02 規格 : [ 100 ug ] List All

Specification Application Image

Product Mouse monoclonal antibody raised against a full length recombinant Western Blot (Cell lysate) Description: ENSA.

Immunogen: ENSA (AAH00436, 1 a.a. ~ 121 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Sequence: MSQKQEEENPAEETGEEKQDTQEKEGILPERAEEAKLKAKYPSLGQKP GGSDFLMKRLQKGQKYFDSGDYNMAKAKMKNKQLPSAGPDKNLVTGD enlarge HIPTPQDLPQRKSSLVTSKLAGGQVE Western Blot (Recombinant protein) Host: Mouse Sandwich ELISA (Recombinant Reactivity: Human protein)

Isotype: IgG2b Kappa

Quality Control Antibody Reactive Against Recombinant Protein. Testing: enlarge

ELISA

Western Blot detection against Immunogen (39.05 KDa) .

Storage Buffer: In 1x PBS, pH 7.4

Storage Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing. Instruction:

MSDS: Download

Datasheet: Download

Applications

Western Blot (Cell lysate)

Page 1 of 3 2016/5/20 ENSA monoclonal antibody (M02), clone 1H7 Western Blot analysis of ENSA expression in K-562 ( Cat # L009V1 ). Protocol Download

Western Blot (Recombinant protein) Protocol Download

Sandwich ELISA (Recombinant protein)

Detection limit for recombinant GST tagged ENSA is approximately 0.1ng/ml as a capture antibody. Protocol Download

ELISA

Gene Information

Entrez GeneID: 2029

GeneBank BC000436 Accession#:

Protein AAH00436 Accession#:

Gene Name: ENSA

Gene Alias: MGC4319,MGC78563,MGC8394

Gene endosulfine alpha Description:

Omim ID: 603061

Gene Ontology: Hyperlink

Gene Summary: The protein encoded by this gene belongs to a highly conserved cAMP- regulated phosphoprotein (ARPP) family. This protein was identified as an endogenous ligand for the sulfonylurea receptor, ABCC8/SUR1. ABCC8 is the regulatory subunit of the ATP-sensitive potassium (KATP) channel, which is located on the plasma membrane of pancreatic beta cells and plays a key role in the control of insulin release from pancreatic beta cells. This protein is thought to be an endogenous regulator of KATP channels. In vitro studies have demonstrated that this protein modulates insulin secretion through the interaction with KATP Page 2 of 3 2016/5/20 channel, and this gene has been proposed as a candidate gene for type 2 diabetes. At least eight alternatively spliced transcript variants encoding distinct isoforms have been observed. [provided by RefSeq

Other OTTHUMP00000032931,OTTHUMP00000032932,OTTHUMP00000034 Designations: 001,OTTHUMP00000034003,OTTHUMP00000034004,OTTHUMP00000 034005,OTTHUMP00000034006

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