Deterministic Quantum Mechanics: the Mathematical Equations∗
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An Introduction to Mathematical Modelling
An Introduction to Mathematical Modelling Glenn Marion, Bioinformatics and Statistics Scotland Given 2008 by Daniel Lawson and Glenn Marion 2008 Contents 1 Introduction 1 1.1 Whatismathematicalmodelling?. .......... 1 1.2 Whatobjectivescanmodellingachieve? . ............ 1 1.3 Classificationsofmodels . ......... 1 1.4 Stagesofmodelling............................... ....... 2 2 Building models 4 2.1 Gettingstarted .................................. ...... 4 2.2 Systemsanalysis ................................. ...... 4 2.2.1 Makingassumptions ............................. .... 4 2.2.2 Flowdiagrams .................................. 6 2.3 Choosingmathematicalequations. ........... 7 2.3.1 Equationsfromtheliterature . ........ 7 2.3.2 Analogiesfromphysics. ...... 8 2.3.3 Dataexploration ............................... .... 8 2.4 Solvingequations................................ ....... 9 2.4.1 Analytically.................................. .... 9 2.4.2 Numerically................................... 10 3 Studying models 12 3.1 Dimensionlessform............................... ....... 12 3.2 Asymptoticbehaviour ............................. ....... 12 3.3 Sensitivityanalysis . ......... 14 3.4 Modellingmodeloutput . ....... 16 4 Testing models 18 4.1 Testingtheassumptions . ........ 18 4.2 Modelstructure.................................. ...... 18 i 4.3 Predictionofpreviouslyunuseddata . ............ 18 4.3.1 Reasonsforpredictionerrors . ........ 20 4.4 Estimatingmodelparameters . ......... 20 4.5 Comparingtwomodelsforthesamesystem . ......... -
INTUITION .THE PHILOSOPHY of HENRI BERGSON By
THE RHYTHM OF PHILOSOPHY: INTUITION ·ANI? PHILOSO~IDC METHOD IN .THE PHILOSOPHY OF HENRI BERGSON By CAROLE TABOR FlSHER Bachelor Of Arts Taylor University Upland, Indiana .. 1983 Submitted ~o the Faculty of the Graduate College of the · Oklahoma State University in partial fulfi11ment of the requirements for . the Degree of . Master of Arts May, 1990 Oklahoma State. Univ. Library THE RHY1HM OF PlllLOSOPHY: INTUITION ' AND PfnLoSOPlllC METHOD IN .THE PHILOSOPHY OF HENRI BERGSON Thesis Approved: vt4;;. e ·~lu .. ·~ests AdVIsor /l4.t--OZ. ·~ ,£__ '', 13~6350' ii · ,. PREFACE The writing of this thesis has bee~ a tiring, enjoyable, :Qustrating and challenging experience. M.,Bergson has introduced me to ·a whole new way of doing . philosophy which has put vitality into the process. I have caught a Bergson bug. His vision of a collaboration of philosophers using his intuitional m~thod to correct, each others' work and patiently compile a body of philosophic know: ledge is inspiring. I hope I have done him justice in my description of that vision. If I have succeeded and that vision catches your imagination I hope you Will make the effort to apply it. Please let me know of your effort, your successes and your failures. With the current challenges to rationalist epistemology, I believe the time has come to give Bergson's method a try. My discovery of Bergson is. the culmination of a development of my thought, one that started long before I began my work at Oklahoma State. However, there are some people there who deserv~. special thanks for awakening me from my ' "''' analytic slumber. -
Duration, Temporality and Self
Duration, Temporality and Self: Prospects for the Future of Bergsonism by Elena Fell A thesis submitted in partial fulfilment for the requirements for the degree of Doctor of Philosophy in Philosophy at the University of Central Lancashire 2007 2 Student Declaration Concurrent registration for two or more academic awards I declare that white registered as a candidate for the research degree, I have not been a registered candidate or enrolled student for another award of the University or other academic or professional institution. Material submitted for another award I declare that no material contained in the thesis has been used in any other submission for an academic award and is solely my own work Signature of Candidate Type of Award Doctor of Philosophy Department Centre for Professional Ethics Abstract In philosophy time is one of the most difficult subjects because, notoriously, it eludes rationalization. However, Bergson succeeds in presenting time effectively as reality that exists in its own right. Time in Bergson is almost accessible, almost palpable in a discourse which overcomes certain difficulties of language and traditional thought. Bergson equates time with duration, a genuine temporal succession of phenomena defined by their position in that succession, and asserts that time is a quality belonging to the nature of all things rather than a relation between supposedly static elements. But Rergson's theory of duration is not organised, nor is it complete - fragments of it are embedded in discussions of various aspects of psychology, evolution, matter, and movement. My first task is therefore to extract the theory of duration from Bergson's major texts in Chapters 2-4. -
Clustering and Classification of Multivariate Stochastic Time Series
Clemson University TigerPrints All Dissertations Dissertations 5-2012 Clustering and Classification of Multivariate Stochastic Time Series in the Time and Frequency Domains Ryan Schkoda Clemson University, [email protected] Follow this and additional works at: https://tigerprints.clemson.edu/all_dissertations Part of the Mechanical Engineering Commons Recommended Citation Schkoda, Ryan, "Clustering and Classification of Multivariate Stochastic Time Series in the Time and Frequency Domains" (2012). All Dissertations. 907. https://tigerprints.clemson.edu/all_dissertations/907 This Dissertation is brought to you for free and open access by the Dissertations at TigerPrints. It has been accepted for inclusion in All Dissertations by an authorized administrator of TigerPrints. For more information, please contact [email protected]. Clustering and Classification of Multivariate Stochastic Time Series in the Time and Frequency Domains A Dissertation Presented to the Graduate School of Clemson University In Partial Fulfillment of the Requirements for the Degree Doctor of Philosophy Mechanical Engineering by Ryan F. Schkoda May 2012 Accepted by: Dr. John Wagner, Committee Chair Dr. Robert Lund Dr. Ardalan Vahidi Dr. Darren Dawson Abstract The dissertation primarily investigates the characterization and discrimina- tion of stochastic time series with an application to pattern recognition and fault detection. These techniques supplement traditional methodologies that make overly restrictive assumptions about the nature of a signal by accommodating stochastic behavior. The assumption that the signal under investigation is either deterministic or a deterministic signal polluted with white noise excludes an entire class of signals { stochastic time series. The research is concerned with this class of signals almost exclusively. The investigation considers signals in both the time and the frequency domains and makes use of both model-based and model-free techniques. -
Random Matrix Eigenvalue Problems in Structural Dynamics: an Iterative Approach S
Mechanical Systems and Signal Processing 164 (2022) 108260 Contents lists available at ScienceDirect Mechanical Systems and Signal Processing journal homepage: www.elsevier.com/locate/ymssp Random matrix eigenvalue problems in structural dynamics: An iterative approach S. Adhikari a,<, S. Chakraborty b a The Future Manufacturing Research Institute, Swansea University, Swansea SA1 8EN, UK b Department of Applied Mechanics, Indian Institute of Technology Delhi, India ARTICLEINFO ABSTRACT Communicated by J.E. Mottershead Uncertainties need to be taken into account in the dynamic analysis of complex structures. This is because in some cases uncertainties can have a significant impact on the dynamic response Keywords: and ignoring it can lead to unsafe design. For complex systems with uncertainties, the dynamic Random eigenvalue problem response is characterised by the eigenvalues and eigenvectors of the underlying generalised Iterative methods Galerkin projection matrix eigenvalue problem. This paper aims at developing computationally efficient methods for Statistical distributions random eigenvalue problems arising in the dynamics of multi-degree-of-freedom systems. There Stochastic systems are efficient methods available in the literature for obtaining eigenvalues of random dynamical systems. However, the computation of eigenvectors remains challenging due to the presence of a large number of random variables within a single eigenvector. To address this problem, we project the random eigenvectors on the basis spanned by the underlying deterministic eigenvectors and apply a Galerkin formulation to obtain the unknown coefficients. The overall approach is simplified using an iterative technique. Two numerical examples are provided to illustrate the proposed method. Full-scale Monte Carlo simulations are used to validate the new results. -
Arxiv:2103.07954V1 [Math.PR] 14 Mar 2021 Suppose We Ask a Randomly Chosen Person Two Questions
Contents, Contexts, and Basics of Contextuality Ehtibar N. Dzhafarov Purdue University Abstract This is a non-technical introduction into theory of contextuality. More precisely, it presents the basics of a theory of contextuality called Contextuality-by-Default (CbD). One of the main tenets of CbD is that the identity of a random variable is determined not only by its content (that which is measured or responded to) but also by contexts, systematically recorded condi- tions under which the variable is observed; and the variables in different contexts possess no joint distributions. I explain why this principle has no paradoxical consequences, and why it does not support the holistic “everything depends on everything else” view. Contextuality is defined as the difference between two differences: (1) the difference between content-sharing random variables when taken in isolation, and (2) the difference between the same random variables when taken within their contexts. Contextuality thus defined is a special form of context-dependence rather than a synonym for the latter. The theory applies to any empir- ical situation describable in terms of random variables. Deterministic situations are trivially noncontextual in CbD, but some of them can be described by systems of epistemic random variables, in which random variability is replaced with epistemic uncertainty. Mathematically, such systems are treated as if they were ordinary systems of random variables. 1 Contents, contexts, and random variables The word contextuality is used widely, usually as a synonym of context-dependence. Here, however, contextuality is taken to mean a special form of context-dependence, as explained below. Histori- cally, this notion is derived from two independent lines of research: in quantum physics, from studies of existence or nonexistence of the so-called hidden variable models with context-independent map- ping [1–10],1 and in psychology, from studies of the so-called selective influences [11–18]. -
Definitions and Standards for Expedited Reporting
European Medicines Agency June 1995 CPMP/ICH/377/95 ICH Topic E 2 A Clinical Safety Data Management: Definitions and Standards for Expedited Reporting Step 5 NOTE FOR GUIDANCE ON CLINICAL SAFETY DATA MANAGEMENT: DEFINITIONS AND STANDARDS FOR EXPEDITED REPORTING (CPMP/ICH/377/95) APPROVAL BY CPMP November 1994 DATE FOR COMING INTO OPERATION June 1995 7 Westferry Circus, Canary Wharf, London, E14 4HB, UK Tel. (44-20) 74 18 85 75 Fax (44-20) 75 23 70 40 E-mail: [email protected] http://www.emea.eu.int EMEA 2006 Reproduction and/or distribution of this document is authorised for non commercial purposes only provided the EMEA is acknowledged CLINICAL SAFETY DATA MANAGEMENT: DEFINITIONS AND STANDARDS FOR EXPEDITED REPORTING ICH Harmonised Tripartite Guideline 1. INTRODUCTION It is important to harmonise the way to gather and, if necessary, to take action on important clinical safety information arising during clinical development. Thus, agreed definitions and terminology, as well as procedures, will ensure uniform Good Clinical Practice standards in this area. The initiatives already undertaken for marketed medicines through the CIOMS-1 and CIOMS-2 Working Groups on expedited (alert) reports and periodic safety update reporting, respectively, are important precedents and models. However, there are special circumstances involving medicinal products under development, especially in the early stages and before any marketing experience is available. Conversely, it must be recognised that a medicinal product will be under various stages of development and/or marketing in different countries, and safety data from marketing experience will ordinarily be of interest to regulators in countries where the medicinal product is still under investigational-only (Phase 1, 2, or 3) status. -
Staphylococcus Aureus Bloodstream Infection Treatment Guideline
Staphylococcus aureus Bloodstream Infection Treatment Guideline Purpose: To provide a framework for the evaluation and management patients with Methicillin- Susceptible (MSSA) and Methicillin-Resistant Staphylococcus aureus (MRSA) bloodstream infections (BSI). The recommendations below are guidelines for care and are not meant to replace clinical judgment. The initial page includes a brief version of the guidance followed by a more detailed discussion of the recommendations with supporting evidence. Also included is an algorithm describing management of patients with blood cultures positive for gram-positive cocci. Brief Key Points: 1. Don’t ignore it – Staphylococcus aureus isolated from a blood culture is never a contaminant. All patients with S. aureus in their blood should be treated with appropriate antibiotics and evaluated for a source of infection. 2. Control the source a. Removing infected catheters and prosthetic devices – Retention of infected central venous catheters and prosthetic devices in the setting of S. aureus bacteremia (SAB) has been associated with prolonged bacteremia, treatment failure and death. These should be removed if medically possible. i. Retention of prosthetic material is associated with an increased likelihood of SAB relapse and removal should be considered even if not clearly infected b. Evaluate for metastatic infections (endocarditis, osteomyelitis, abscesses, etc.) – Metastatic infections and endocarditis are quite common in SAB (11-31% patients with SAB have endocarditis). i. All patients should have a thorough history taken and exam performed with any new complaint evaluated for possible metastatic infection. ii. Echocardiograms should be strongly considered for all patients with SAB iii. All patients with a prosthetic valve, pacemaker/ICD present, or persistent bacteremia (follow up blood cultures positive) should undergo a transesophageal echocardiogram 3. -
The Relationship of Drought Frequency and Duration to Time Scales
Eighth Conference on Applied Climatology, 17-22 January 1993, Anaheim, California if ~ THE RELATIONSHIP OF DROUGHT FREQUENCY AND DURATION TO TIME SCALES Thomas B. McKee, Nolan J. Doesken and John Kleist Department of Atmospheric Science Colorado State University Fort Collins, CO 80523 1.0 INTRODUCTION Five practical issues become important in any analysis of drought. These include: 1) time scale, 2) The definition of drought has continually been probability, 3) precipitation deficit, 4) application of the a stumbling block for drought monitoring and analysis. definition to precipitation and to the five water supply Wilhite and Glantz (1985) completed a thorough review variables, and 5) the relationship of the definition to the of dozens of drought definitions and identified six impacts of drought. Frequency, duration and intensity overall categories: meteorological, climatological, of drought all become functions that depend on the atmospheric, agricultural, hydrologic and water implicitly or explicitly established time scales. Our management. Dracup et al. (1980) also reviewed experience in providing drought information to a definitions. All points of view seem to agree that collection of decision makers in Colorado is that they drought is a condition of insufficient moisture caused have a need for current conditions expressed in terms by a deficit in precipitation over some time period. of probability, water deficit, and water supply as a Difficulties are primarily related to the time period over percent of average using recent climatic history (the which deficits accumulate and to the connection of the last 30 to 100 years) as the basis for comparison. No deficit in precipitation to deficits in usable water single drought definition or analysis method has sources and the impacts that ensue. -
MCA 504 Modelling and Simulation
MCA 504 Modelling and Simulation Index Sr.No. Unit Name of Unit 1 UNIT – I SYSTEM MODELS & SYSTEM SIMULATION 2 UNIT – II VRIFICATION AND VALIDATION OF MODEL 3 UNIT – III DIFFERENTIAL EQUATIONS IN SIMULATION 4 UNIT – IV DISCRETE SYSTEM SIMULATION 5 UNIT – V CONTINUOUS SIMULATION 6 UNIT – VI SIMULATION LANGUAGE 7 UNIT – USE OF DATABASE, A.I. IN MODELLING AND VII SIMULATION Total No of Pages Page 1 of 138 Subject : System Simulation and Modeling Author : Jagat Kumar Paper Code: MCA 504 Vetter : Dr. Pradeep Bhatia Lesson : System Models and System Simulation Lesson No. : 01 Structure 1.0 Objective 1.1 Introduction 1.1.1 Formal Definitions 1.1.2 Brief History of Simulation 1.1.3 Application Area of Simulation 1.1.4 Advantages and Disadvantages of Simulation 1.1.5 Difficulties of Simulation 1.1.6 When to use Simulation? 1.2 Modeling Concepts 1.2.1 System, Model and Events 1.2.2 System State Variables 1.2.2.1 Entities and Attributes 1.2.2.2 Resources 1.2.2.3 List Processing 1.2.2.4 Activities and Delays 1.2.2.5 1.2.3 Model Classifications 1.2.3.1 Discrete-Event Simulation Model 1.2.3.2 Stochastic and Deterministic Systems 1.2.3.3 Static and Dynamic Simulation 1.2.3.4 Discrete vs Continuous Systems 1.2.3.5 An Example 1.3 Computer Workload and Preparation of its Models 1.3.1Steps of the Modeling Process 1.4 Summary 1.5 Key words 1.6 Self Assessment Questions 1.7 References/ Suggested Reading Page 2 of 138 1.0 Objective The main objective of this module to gain the knowledge about system and its behavior so that a person can transform the physical behavior of a system into a mathematical model that can in turn transform into a efficient algorithm for simulation purpose. -
Miracles: Metaphysics, Physics, and Physicalism
Religious Studies 44, 125–147 f 2008 Cambridge University Press doi:10.1017/S0034412507009262 Printed in the United Kingdom Miracles: metaphysics, physics, and physicalism KIRK MCDERMID Department of Philosophy and Religion, Montclair State University, Montclair, NJ 07403 Abstract: Debates about the metaphysical compatibility between miracles and natural laws often appear to prejudge the issue by either adopting or rejecting a strong physicalist thesis (the idea that the physical is all that exists). The operative component of physicalism is a causal closure principle: that every caused event is a physically caused event. If physicalism and this strong causal closure principle are accepted, then supernatural interventions are ruled out tout court, while rejecting physicalism gives miracles metaphysical carte blanche. This paper argues for a more moderate version of physicalism that respects important physicalist intuitions about causal closure while allowing for miracles’ logical possibility. A recent proposal for a specific mechanism for the production of miracles (Larmer (1996d)) is criticized and rejected. In its place, two separate mechanisms (suitable for deterministic and indeterministic worlds, respectively) are proposed that do conform to a more moderate physicalism, and their potential and limitations are explored. Introduction Many writers assert that miracles are law-violating instances (Swinburne (1970), Odegard (1982), Collier (1996), MacGill (1996)), but respondents claim that this idea is variously incoherent (McKinnon (1967), Flew (1967)), or false (Basinger (1984), Larmer (1996a)). The incoherence charge only applies to a strictly Humean view of laws as merely accounts of what actually happened (McKinnon (1967)), not to more robust views of laws as representing some variety of physical necessity or causal power. -
Safety Reporting Requirements for Inds and BA/BE Studies
Guidance for Industry and Investigators Safety Reporting Requirements for INDs and BA/BE Studies U.S. Department of Health and Human Services Food and Drug Administration Center for Drug Evaluation and Research (CDER) Center for Biologics Evaluation and Research (CBER) December 2012 Drug Safety Guidance for Industry and Investigators Safety Reporting Requirements for INDs and BA/BE Studies Additional copies are available from: Office of Communications Division of Drug Information, WO51, Room 2201 Center for Drug Evaluation and Research Food and Drug Administration 10903 New Hampshire Ave. Silver Spring, MD 20993-0002 Phone: 301-796-3400; Fax: 301-847-8714 [email protected] http://www.fda.gov/Drugs/GuidanceComplianceRegulatoryInformation/Guidances/default.htm or Office of Communication, Outreach and Development, HFM-40 Center for Biologics Evaluation and Research Food and Drug Administration 1401 Rockville Pike, Suite 200N, Rockville, MD 20852-1448 [email protected]; Phone: 800-835-4709 or 301-827-1800 http://www.fda.gov/BiologicsBloodVaccines/GuidanceComplianceRegulatoryInformation/default.htm U.S. Department of Health and Human Services Food and Drug Administration Center for Drug Evaluation and Research (CDER) Center for Biologics Evaluation and Research (CBER) December 2012 Drug Safety TABLE OF CONTENTS I. INTRODUCTION..............................................................................................................................................1 II. BACKGROUND AND BRIEF OVERVIEW OF THE REQUIREMENTS.................................................1