(12) Patent Application Publication (10) Pub. No.: US 2011/0104238A1 Haas Et Al
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US 2011 0104238A1 (19) United States (12) Patent Application Publication (10) Pub. No.: US 2011/0104238A1 Haas et al. (43) Pub. Date: May 5, 2011 (54) WETTABLE FILLERS FOR IMPROVED Publication Classification RELEASE OF HYDROPHILIC MATERALS (51) Int. Cl FROM CHEWING GUM COMPOSITIONS A69/68 (2006.01) A633/42 2006.O1 (76) Inventors: Michael S. Haas, Naperville, IL A6IP 9/00 388 (US); Darei C. Biesczat, Crown A23G 4/00 (2006.01) Point, IN (US); Pamela M. A23G 4/06 (2006.01) Mazurek, Orland Park, IL (US) A23G 4/20 (2006.01) (52) U.S. Cl. ............... 424/440; 424/48; 424/602; 426/3; (21) Appl. No.: 12/867,178 42675 (57) ABSTRACT (22) PCT Filed: Feb. 10, 2009 A chewing gum is provided in the present disclosure. In an embodiment, the chewing gum comprises at least one wet (86). PCT No.: PCT/US2O09/033643 table filler wherein the wettable filler aids in producing an S371 (c)(1) increasing release of one or more hydrophilic additives. In (2), (4) Date: Dec. 7, 2010 another embodiment, the chewing gum comprises a wettable s 9 filler having a Y in a range of at least 15.0 mJ/m to about 65.0 O O mJ/m, wherein the wettable filler aids in increasing the Related U.S. Application Data release of at least one hydrophilic additive. A method for (60) Provisional application No. 61/029,227, filed on Feb. increasing the release of one or more hydrophilic additives in 15, 2008. a chewing gum composition is also provided. Patent Application Publication May 5, 2011 Sheet 1 of 3 US 2011/O104238A1 Figure 1 Material y DCPD 31.7 HAP 16.0 OCP 19.7 FAP 9.0 TaC 2.7 Smectite 33.3 Muscovite (mica) 57.7 Teflon O Glass 34.0 1.O 64.2 Figure 2 15 -8-EX 2a 15 ... & EX 2a -A-EX 1a (Mean) -A-EX 1a (Mean) 12 12 - & Baseline ---. Baseline 6 8 10 12 14 16 O 2 4 6 8 10 12 14 16 Time (min) Time (min) Patent Application Publication May 5, 2011 Sheet 2 of 3 US 2011/O104238A1 Figure 3 -A-Ex 1a (Mean) 15 - -A-EX 1a (Mean) --&- Baseline -- Baseline was EX 2b ...sa...EX 2b 12 ... &. EX 2a assrsarrasara-Saar 6 8 10 12 14 16 6 8 10 12 14 16 Time (min) Time (min) Figure 4 15 -A-Ex 1a (Mean) 15 - -A-EX 1a (Mean) --&- Baseline ...&. Baseline -&----. Ex 1C 12 awa EX 1C ... 8.....EX 1e 2 6 8 10 12 14 16 6 8 10 12 14 16 Time (min) Time (min) Patent Application Publication May 5, 2011 Sheet 3 of 3 US 2011/0104238A1 Figure 5 15 - -A-Ex 1a (Mean) 15 - -A-Ex 1a (Mean) --&c. Baseline - car&rarr Baseline aSa Ex 1C - sa. Ex 1C - ... &.... Ex1d S O 3.x-r&ro-room-m$ 0 2 4 6 8 10 12 14 16 O 2 4 6 8 10 12 14 16 Time (min) Time (min) US 2011/0104238 A1 May 5, 2011 WETTABLE FILLERS FOR IMPROVED Sweeteners, flavors, medicaments or combinations thereof. RELEASE OF HYDROPHILIC MATERALS The hydrophilic additive may include, for example, choline, FROM CHEWING GUM COMPOSITIONS lipoic acid, inositol, B (Thiamine, Sulbutiamine, Benfo tiamine), B (Riboflavin), B (Niacin, Nicotinamide), Bs BACKGROUND (Pantothenic acid, Dexpanthenol, Pantethine), B (Pyridox ine, Pyridoxal phosphate), B, (Biotin), B (Folic acid), B. 0001. The present disclosure generally relates to chewing (Cyanocobalamin, Hydroxocobalamin, Mecobalamin) and gum compositions. More specifically, the present disclosure combinations thereof. relates to chewing gum compositions that use fillers to pro 0010. In an embodiment, the hydrophilic additive may mote optimal release of Substances having hydrophilic prop also include, for example, Sucralose, aspartame, NAPM erties. derivatives such as neotame, salts of acesulfame, TwinSweet 0002 Most chewing gums including an additive and/or (aspartame-acesulfame salt), altitame, saccharin and its salts, medicament having hydrophilic properties often experience cyclamic acid and its salts, glycyrrhizin, dihydrochalcones, incomplete release and/or retardation of late term release. This is due to the additive(s) binding to the chewing gum base thaumatin, monellin or combinations thereof. portion due to the base's hydrophobic nature. Further, the 0011. In an embodiment, the hydrophilic additive is ineffective release of these additives may stem from the addi coated, encapsulated, agglomerated or absorbed. tive continuously reabsorbing into the chewing gum matrix 0012. In another embodiment, the present disclosure pro during mastication. As a result, the hydrophilic additive never vides a chewing gum comprising a wettable filler having a YT completely releases from the chewing gum composition, thus in a range of at least 25.0 m.J/m to about 65.0 mJ/m. offering less then optimal sensorial characteristics and/or 0013. In yet another embodiment, the present disclosure health benefits. provides a chewing gum comprising a wettable filler having a 0003 For example, the problem of incomplete release Y in a range of at least 15.0 mJ/m to about 65.0 mJ/m. The and/or retardation of late term release occurs when applying wettable filler aids in increasing the release at least one hydro salts to chewing gum for the benefit of tooth remineralization. philic additive. The hydrophilic additive may include, for Chewing gums containing salts, such as calcium and phos example, vitamins, salts, Sweeteners, flavors, medicaments phate salts, for tooth remineralization experience both an and combinations thereof. incomplete release and retardation of late term release, thus 0014. In an embodiment, the wettable filler may include, never completely releasing from the chewing gum composi for example, tricalcium phosphate, octacalcium phosphate, tion offering less than optimal remineralization benefits to the tetracalcium phosphate or combinations thereof. COSU. (0015. Alternatively, the wettable filler may include, for 0004 Generally, to compensate for this reduced release of example, anhydrous dicalcium phosphate, Smectite, musco partially to fully hydrophilic materials from chewing gums, vite or combinations thereof. developers formulate alternative means to promote efficient 0016. In an embodiment, the hydrophilic additive may release. These alternatives often compromise taste, flavor, include, for example, vitamin C, ascorbic acid and salts sensorial characteristics of the chewing gum composition, thereof, or combinations thereof. The hydrophilic acid may can lead to increase production costs, and ultimately diminish also include, for example, calcium, potassium, Sodium the opportunity for delivering the benefits that a consumer can ammonium, pyrophosphate, Zinc and copper salts or combi receive from the chewing gum composition. As a result, for nations thereof. mulating for the effective release of active compounds from 0017. In a further embodiment, the present disclosure pro chewing gum compositions is gathering attention. vides a chewing gum comprising at least one wettable filler 0005. Therefore, a need exists for a chewing gum that having a Y greater than 15.0 mJ/m. The wettable filler aids improves the release characteristics of hydrophilic additives in improving the release of one or more hydrophilic additives Such as salts, vitamins, Sweeteners, flavors and other medica Such as, for example, calcium citrate, potassium phosphate, ments for consumer and/or health benefits. Sodium phosphate or combinations thereof. 0018. In another embodiment, the present disclosure pro SUMMARY vides a method for increasing the release of hydrophilic addi 0006. The present disclosure generally relates to chewing tives in a gum composition. The method comprises adding at gum compositions. More specifically, the present disclosure least one wettable filler to a chewing gum composition com relates to chewing gum compositions that improve the release prising one or more hydrophilic additives. The wettable filler of hydrophilic additives. aids in increasing the release of the one or more hydrophilic 0007. In an embodiment, the present disclosure provides a additives. The hydrophilic additive may be, for example, cal chewing gum comprising at least one wettable filler. The cium, potassium, sodium, ammonium, pyrophosphate salts or wettable filler aids in producing an increased release of one or combinations thereof. Alternatively, the hydrophilic additive more hydrophilic additives. is calcium citrate. Further, the hydrophilic additive may be, 0008. In an embodiment, the wettable filler can have a Y for example, braZZein, luo hanguo, Steviol glycosides, rebau greater than 15.0 m.J/m. The wettable filler may be a phyl dioside A, Rebiana, monatin or combinations thereof. losilicate. Alternatively, the wettable filler may include, for 0019. In an embodiment, the rate of release of one or more example, monocalcium phosphate, dicalcium phosphate hydrophilic additives is greater than about six minutes during dihydrate, anyhydrous dicalcium phosphate, tricalcium phos mastication of the gum composition. phate, octacalcium phosphate, tetracalcium phosphate, Smec 0020. In an embodiment, the hydrophilic additive is a fruit tite, muscovite or combinations thereof. flavor. 0009. In an embodiment, the hydrophilic additive having 0021. An advantage of the present disclosure is to provide improved release includes, for example, Vitamins, salts, an improved chewing gum composition. US 2011/0104238 A1 May 5, 2011 0022. Another advantage of the present disclosure is to 0040. It has been found that the cause for the incomplete provide a more optimal release of a variety of hydrophilic and retarded release of salts and other compounds such as materials in chewing gums. Vitamins, Sweeteners, flavors and medicaments, relates to the 0023. A further advantage of the present disclosure is to wettability and non-wettability of the fillers employed in provide a chewing gum composition that promotes a more chewing gum compositions. complete and late release of hydrophilic materials contained 0041. For example, molecules inside a composition (liq in the composition. uid or solid) are in every direction affected by equal attraction 0024. Still another advantage of the present disclosure is to forces, whereas molecules at the Surface lack a neighbor at the provide a chewing gum composition with improved sensorial air phase and therefore have larger attraction forces towards benefits.