ESOT2021
POS-008
socioeconomically . . retrospectively and
[email protected] mail: - E
etiologically, etiologically, evaluated were 2020 December
intake.
, Istanbul, Turkey Istanbul, , Fatih
9. 9. - ;224(4):485 2019
Transplantation Unit between January 2013 and and 2013 January between Unit Transplantation
patients’ age, oral dose per medicine, frequency, and dosage of IV calcium calcium IV of dosage and frequency, medicine, per dose oral age, patients’
, 34093, 34093, , Caddesi Vatan , Bulvari Menderes Adnan : ress d Ad
. . Immunobiology . allotransplantation parathyroid successful
Department of General Surgery, Parathyroid Parathyroid Surgery, General of Department
list, estimated from variables including the etiology of hypoparathyroidism, hypoparathyroidism, of etiology the including variables from estimated list, for tests DSA and PRA , typing HLA of Importance al. at Yucesan 4
Kaya MD. Kaya Salepçioğlu Harika : Correspondence
Medicine of Faculty University, Vakif Bezmialem , ,
Harika Salepcioglu Kaya Salepcioglu Harika tissue Composite waiting the on patients prioritizing for used be may system scoring a that suggest 53. 53. - ;101(8):3045 2016
CONTACT INFORMATION CONTACT
. . Metab Endocrinol Clin J . Norway in Hypoparathyroidism
patients who have enrolled on the waiting list of the the of list waiting the on enrolled have who patients The transplantation is the most effective curative treatment option. We We option. treatment curative effective most the is transplantation Parathyroid
of Life in in Life of Quality Related - Health and Epidemiology al. at Astor 3
list for transplantation. for list
. terms socioeconomical in , ages productive most their at population young this in
;31(11). ;31(11). 2017
have been registered on the waiting waiting the on registered been have causes autoimmune
the etiology. These data show that hypoparathyroidism is a public health problem problem health public a is hypoparathyroidism that show data These etiology. the . . Transplant Clin . up - follow year - 1 : immunosuppression term
. 0 202 December
hypoparathyroidism for iatrogenic or idiopathic or or idiopathic or iatrogenic for hypoparathyroidism - short with allotransplantation parathyroid tissue Fresh al. et Yucesan 2
most most Unit, our In patients were between 30 and 49 years old, regardless of of regardless old, years 49 and 30 between were patients the of between December 2013 and and 2013 December between Hospital University f i Vak
To date, 304 of the patients who were diagnosed with with diagnosed were who patients the of 304 date, To 85. 85. - ;28(11):2277 2013 Res. Miner Bone J study. up - follow historic Nephrology and Organ Transplantation Transplantation Organ and Nephrology nits of Bezmialem Bezmialem of nits U
vitamin D, with the necessity of hospitalizations in 12.8% of the patients. patients. the of 12.8% in hospitalizations of necessity the with D, vitamin
postsurgical hypoparathyroidism: a Danish nationwide controlled controlled nationwide Danish a hypoparathyroidism: postsurgical /worked in the General Surgery, Endocrinology, Endocrinology, Surgery, General the in /worked s work who
particularly young people needing daily supplementations of calcium and and calcium of supplementations daily needing people young particularly METHOD Underbjerg 1 and renal complications to to complications renal and Cardiovascular al. at
and the relevant healthcare professionals professionals healthcare relevant the and ypoparathyroidism h
Permanent hypoparathyroidism has an elevated socioeconomic cost, affecting affecting cost, socioeconomic elevated an has hypoparathyroidism Permanent We would like to thank all our patients diagnosed with with diagnosed patients our all thank to like would We
CONCLUS ONS I ACKNOWLEDGEMENTS REFERENCES
. . retrospectively , medication
and dosage of the the of dosage and features epidemiological their by list
day µg/ . .
parathyroid assess to is aim Our waiting transplantation
. list waiting the
intake calcitrol and, day IU/ in intake cholecalciferol , day mg/ in listed intake calcium and presented were in in
distribution of patients on on patients of distribution Etiological : 3 Figure
gender.
Figure 2 Figure values Mean . list waiting the on patients of intake cholecalciferol and calcitriol, , alcium c Daily :
. . 1) (Figure ) old years 49 and 20 between ( period
I A M
Age distribution of patients on the waiting list by by list waiting the on patients of distribution Age : 1 Figure
congenital idiopatic
Calcitriol Cholecalciferol Calcium reproductive their in are patients female (65%)
>49 <50 <40 <30 <20 autoimmune iatrogenic
>49 <50 <40 <30 <20
, 116 of 178 178 of 116 , Particularly . (15.6%) male are 33 0 0
1
3
4 1
7
9
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female and and female are (84.4%) patients these of 178 old. 500
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1917
). 4 , 3 (1, treatment palliative of part as factors important 2009 1000
between 30 and 49 years years 49 and 30 between are (61%) patients 128
2160
2310 2324
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0,72
39
1500 3056 vitamin D which is considered to be one of the most most the of one be to considered is which D vitamin
0,8 ). ). 21790 II class - for and 18594 I class HLA for 0,83
1
2000
defined criteria for the need for daily calcium and active active and calcium daily for need the for criteria defined
1,07
. MFI MFI . max and 2000 MFI min. ( PRA high a ve ha 1,12
61
1,2
2500
68 National and international guidelines and, literature has no no has literature and, guidelines international and National
1,4 six patients patients six , addition In . transplant second their
3000
3 1,58
1,6
. . hypoparathyroidism
for for waiting are (7%) people 14 transplantation,
3500 1,8
of of symptoms the ease to sufficient not is treatment for their first first their for waiting are (93%) people DRUG DOSES REPARTITION BY AGE BY REPARTITION DOSES DRUG
palliative that indicates outcome The (3). antidepressants
197 197 197 them among ; transplantation parathyroid
to use use to enough serious problems social have
Currently, 211 patients are still waiting for for waiting still are patients 211 Currently, 10 8.54 8.44 (mg/dL) Calcium 7.83 8.25
patients patients the of majority that noted also was It job. simpler
1.87 5.89 (pg/mL) PTH 1.63 3.6
18
work in any job and 54% of the patients had to switch to a a to switch to had patients the of 54% and job any in work
ETIOLOGY
118 months. months. 118 found was list transplantation Iatrogenic Value Mean ongenital C Autoimmune
Field studies showed 25% of the patients were unable to to unable were patients the of 25% showed studies Field
of hypoparathyroidism before enrolling on the the on enrolling before hypoparathyroidism of of of etiology by levels calcium and PTH : 1 Table . hypoparathyroidism
shows a significant decrease (2). (2). decrease significant a shows
waiting time of 48 months. The average duration duration average The months. 48 of time waiting
calcitriol , and cholecalciferol , calcium (Figure 2). 2). (Figure determined were distribution age the on depending intake
and active vitamin D preparations, but their quality of life life of quality their but preparations, D vitamin active and
since, with an average average an with since, transplanted were
Presented them
8.44mg/dL, 8.54mg/dL, 8.25mg/dL and 7.83mg/dL, respectively in each etiological group etiological each in respectively 7.83mg/dL, and 8.25mg/dL 8.54mg/dL, 8.44mg/dL, . The mean daily daily mean The . 1) Table (
male female
hypoparathyroidism (1). These patients use daily calcium calcium daily use patients These (1). hypoparathyroidism
transplantation were found eligible and 93 of of 93 and eligible found were transplantation GENDER
3.6pg/mL and 1.63pg/mL, in each etiological group, group, etiological each in 1.63pg/mL, and 3.6pg/mL mean calcium levels were were levels calcium mean The . 3) Figure ( respectively
cramping are seen in patients with permanent permanent with patients in seen are cramping
AGE REPARTITION BY BY REPARTITION AGE
304 patients who enrolled for parathyroid parathyroid for enrolled who patients 304 The The . patients of 2% in congenital and , 1.87pg/mL, 1.87pg/mL, , 5.89pg/mL were
at: levels (PTH) hormone parathyroid intact mean
Symptoms such as fatigue and and fatigue as such Symptoms life. of quality in decrease
was iatrogenic in 94% of the patients, autoimmune in 3%, idiopathic in 1%, 1%, in idiopathic 3%, in autoimmune patients, the of 94% in iatrogenic was hypoparathyroidism of etiology The
significant a causes hypoparathyroidism Permanent
RESULTS
INTRODUCTION
Nephrology of Division , Medicine Internal of Department
, , Medicine of Faculty , University Vakıf Bezmialem , Unit Transplantation , , Medicine of Faculty , University Vakıf Bezmialem , Biology Medical of Department
3 4
of General General of Department , Medicine of Faculty , University Vakıf Bezmialem Parathyroid Center, Research Experimental , University Vakıf Bezmialem , Surgery
1 2
, O. F. Duzenli F. O. , Karatoprak U. , Goncu B. , Kaya Salepcioglu H. , A. Akcakaya A. , Kazancioglu R. , Ersoy E. Y. , Yucesan E. ,
2 2 1 1 4 1 3 2
as a a as while patients hypoparathyroidism transplantation parathyroid of candidate
features epidemiological of Evaluation permanent for medication the of dosage and