(12) United States Patent (10) Patent No.: US 8,577,458 B1 Libbus Et Al
US008577458B1 (12) United States Patent (10) Patent No.: US 8,577,458 B1 Libbus et al. (45) Date of Patent: Nov. 5, 2013 (54) IMPLANTABLE DEVICE FOR PROVIDING FOREIGN PATENT DOCUMENTS ELECTRICAL STIMULATION OF CERVICAL VAGUS NERVES FORTREATMENT OF WO O3O18113 3, 2003 CHRONIC CARDAC DYSFUNCTION WITH WO O3O99373 12/2003 LEADLESS HEART RATE MONITORING (Continued) OTHER PUBLICATIONS (75) Inventors: Imad Libbus, St. Paul, MN (US); Badri Amurthur, Los Gatos, CA (US); Bruce Armour, J.A., “Potential clinical relevance of the little brain on the H. KenKnight, Maple Grove, MN (US) mammalian heart.” Experimental Physiology, vol. 93, No. 2, pp. 165-176 (Feb. 2008). Online Publication Date: Nov. 2, 2007. Avail (73) Assignee: Cyberonics, Inc., Houston, TX (US) able at: http://ep.physoc.org/content/93/2/165.long. Castoro et al., “Excitation properties of the right cervical vagus nerve (*) Notice: Subject to any disclaimer, the term of this in adult dogs.” Experimental Neurology, vol. 227, iss. 1. pp. 62-68 patent is extended or adjusted under 35 (Jan. 2011). Online Publication Date: Sep. 17, 2010. Available at: U.S.C. 154(b) by 0 days. http://www.sciencedirect.com/science/article?pii/ SOO1448861OOO347X. (21) Appl. No.: 13/314,126 De Ferrariet al., “Chronic vagus nervestimulation: a new and prom ising therapeutic approach for chronic heart failure.” European Heart (22) Filed: Dec. 7, 2011 Journal, vol. 32, iss. 7, pp. 847-855 (Apr. 2011). Online publication date: Oct. 28, 2010. Available at: http://eurheart.oxfordjournals.org/ (51) Int. Cl. content/32/7/847.long. A61N L/05 (2006.01) (52) U.S.
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