Pediatric PROGRESS
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BECOMING A BETTER BOSS AT THE BENCH JULY 2019 THE LEADING MAGAZINE FOR ENDOCRINOLOGISTS INTERNATIONAL Pediatric PROGRESS The Vital Role of Endocrine Science in Advancing Children’s Health SNACK ATTACKS: Screen time’s relationship with unhealthy snacking in adolescents. GROWING PAINS & GAINS: An ENDO 2019 study shows a link between obesity and precocious puberty in boys. NEWBORN CONUNDRUM: Addressing the challenges treating infants with differences in sex development. A DELICATE BALANCE: New Society guideline on treating older patients with diabetes PAYING TRIBUTE: Remembering Lewis Braverman & Elizabeth Barrett-Connor THE LEADING MAGAZINE FOR ENDOCRINOLOGISTS 2017 – 2019 EDITORIAL ADVISORY BOARD Henry Anhalt, DO Bergen County Pediatric Endocrinology Chair, Hormone Health Network VP, Medical Affairs, Science 37 Sally Camper, PhD Department of Human Genetics University of Michigan Medical School Rodolfo J. Galindo, MD Assistant Professor of Medicine Mount Sinai School of Medicine Christian M. Girgis, MBBS, PhD, FRACP Royal North Shore and Westmead Hospitals University of Sydney, Australia Andrea Gore, PhD Division of Pharmacology and Toxicology University of Texas Daniel A. Gorelick, PhD Baylor University, Houston, Texas M. Carol Greenlee, MD, FACP Western Slope Endocrinology Grand Junction, Colo. (Faculty for Transforming Clinical Practice initiative [TCPi]) GET THE CASE Gary D. Hammer, MD, PhD STUDIES YOU NEED Millie Schembechler Professor of Adrenal Cancer, Endocrine Oncology Program OF ALL ASPECTS OF University of Michigan Robert W. Lash, MD ENDOCRINOLOGY! Chief Professional & Clinical Officer, Endocrine Society Improve patient care with cases from the Karl Nadolsky, DO popular live Meet-the-Professor sessions Diabetes Obesity & Metabolic Institute Walter Reed National Military Medical Center presented during ENDO 2019. Uniformed Services University Earn 30 AMA PRA Category 1 Credits™. Joshua D. Safer, MD, FACP Available in print or eBook. Center for Transgender Medicine and Surgery, Endocrinology Fellowship Training Boston Medical Center; Boston University School of Medicine ENDOCRINE.ORG/STORE Shehzad Topiwala, MD, FACE Endocrinology Department SevenHills Hospital, Mumbai, India Kristen R. Vella, PhD Beth Israel Deaconess Medical Center Harvard Medical School Christina Wang, MD UCLA Clinical and Translational Science Institute Harbor – UCLA Medical Center © 2019 ENDOCRINE SOCIETY JULY 2019 IN THIS ISSUE 16 | Pediatric Obesity and Male Precocious Puberty: A Link Established While the connection has been well-established between obesity and precocious puberty in girls, a Chilean study presented at ENDO 2019 establishes a link between obesity and precocious puberty in boys. T BY KELLY HORVATH 26 | Heavy Player One: How Screen Time and Snacking Impacts Adolescent Metabolic Health A study presented at ENDO 2019 seems to indicate a link between teens who spend a lot of time in front of a screen and poor metabolic health. U Due to the propensity of so many adolescents to snack while they gaze at 20 everything from a television to a cell phone, strategies are needed to address these unhealthy habits. FEATURE BY DEREK BAGLEY 28 | A Newborn Conundrum: Difference in Sex Development in Infants 32 | A Delicate Balance: Treating Older Patients with Diabetes Not as rare as previously thought, babies born with differences in sex development can present a vast array of challenges to Older patients with diabetes can benefit from even more carefully personalized clinicians, as well as to parents and the patients themselves. treatment than their younger counterparts. A new Endocrine Society clinical These cases require an experienced team of specialists from a practice guideline provides a new look at how to care for this growing variety of disciplines to ensure healthy and normal development. population. BY DEREK BAGLEY BY ERIC SEABORG 2 | PRESIDENT’S VIEWPOINT 9 | TRENDS & INSIGHTS 37 | ADVOCACY 44 | CLASSIFIEDS Celebrating 25 years of diversity in Long-term cancer treatment’s Endocrine Society opposes Career opportunities endocrinology effects on the endocrine gene patent legislation; system; BPA exposure has Action on NIH appropriations 45 | HORMONE HEALTH 4 | FROM THE EDITOR transgenerational effects in Congress; Raising public NETWORK A Focus on the Youngest on gene linked to autism; awareness for International NASH Hypoglycemia Fact Sheet Patients and dapagliflozin reduces Day; Endocrine-related policy progression of kidney disease, resolutions at AMA HOD; Advocacy 6 | INTOUCH renal death in patients with type made easy. Queen Elizabeth honors V. Craig 2 diabetes. Jordan; Remembering Elizabeth BY DEREK BAGLEY 42 | LAB NOTES Barrett-Connor and Lewis HOW TO BE A BETTER BOSS Braverman. 12 | ENDOCRINE ITINERARY Aside from having to deal with Scientific meetings of interest your research, grants, safety, and other concerns in your lab, another to endocrinologists from around www.endocrine.org the world important task is managing your staff. Endocrine News has compiled some 15 | DASHBOARD basic hacks on how to be a better Follow us on Twitter: Highlights from the world of manager. @Endocrine_News endocrinology BY GLENDA FAUNTLEROY SHAW ENDOCRINE NEWS | JULY 2019 | 1 PRESIDENT’S VIEWPOINT rom my perspective, valuing a diverse and inclusive global community is essential to furthering the field of endocrinology, enriching the biomedical workforce, improving the care and outcomes of endocrine patients, and Fensuring the ongoing growth and development of our organization. Over the past 25 years, we have committed to creating unique opportunities to support the recruitment, retention, and engagement of diverse talent in endocrinology and increase the Committee visibility and participation of underrepresented groups within the organization. on Diversity Through the dedicated efforts of the Minority Affairs Committee (MAC), now known as the Committee on Diversity and Inclusion (CoDI), we have a robust and Inclusion: portfolio of activities specifically designed to meet our goal to develop and support a diverse and inclusive network of clinician, researcher, and educator members and leaders who promote health, advance research, and work to eliminate 25 Years endocrine health disparities in our local, national, and global communities. For the Society, diversity and inclusion is defined broadly to encompass all aspects of Celebrating diversity – culture, age, ethnicity, race, gender, nationality, professional level, and Diversity in sexual orientation. Currently one of our premier programs, the Future Leaders Advancing Research Endocrinology in Endocrinology Program (FLARE) is a thriving and highly successful leadership training program that has equipped students, fellows, and junior faculty of underrepresented groups with leadership skills that strengthen their confidence as biomedical researchers. Since 2013, FLARE has trained 125 fellows through a Valuing a diverse“ and inclusive global community is essential to furthering the field of endocrinology, enriching the biomedical workforce, improving the care and outcomes of endocrine patients, and ensuring the ongoing growth and development of our organization. ” multi-faceted program approach to leadership development that includes a skills workshop, structured mentoring network and collaborative opportunities, and an internship program. On a personal note, it has been a privilege to have directed the FLARE program since its inception. I want to acknowledge the devoted faculty and Society members who have taught and mentored our FLARE trainees and all the Endocrine Society staff such as Kirsta Suggs, who has supported the program since its inception, and Tracy Williams, who coordinates many of its activities. 2 | JULY 2019 | ENDOCRINENEWS.ORG Our annual meeting (ENDO) programming offers myriad to acknowledge and congratulate all the past and current opportunities to network with diverse groups of endocrinologists members and chairs of MAC and CoDI for their tireless efforts and engage in scientific discussion around minority healthcare and contributions to creating programming that has supported and health disparities. In addition to scientific symposia that and nurtured all of our members. Activities have ranged from cover the latest advances in issues related to these topics, the the Shortcourses in Endocrinology program that has reached CoDI offers workshops such as “Impacting Perceptions and Bias thousands of students at minority-serving institutions, to the Minority Access Program that trained undergraduate students from underrepresented minority groups. We have and will continue to embrace internal and external outreach activities, “ student and professional development activities, and efforts There are many exciting opportunities that reduce endocrine-related health disparities through within the Endocrine Society that integrated activities. promote cultural diversity while I am excited about the progress we’ve made and look forward building an inclusive community for to an even greater impact in the future. all endocrinologists to thrive. If you have any comments or questions, please let me know at [email protected]. ” — E. Dale Abel, MD, PhD, President, Endocrine Society in Healthcare and Research” to address unconscious bias and collaboratively identify strategies to reduce bias in these settings. Our Health Disparities Poster Previews featured six top-scored posters on endocrine-related health disparities to help build 2019 Endocrinology Update & Review Course awareness around