Tobacco Smoke, Indoor Air Pollution and Tuberculosis: a Systematic Review and Meta-Analysis
PLoS MEDICINE Tobacco Smoke, Indoor Air Pollution and Tuberculosis: A Systematic Review and Meta-Analysis Hsien-Ho Lin1, Majid Ezzati2, Megan Murray1,3,4* 1 Department of Epidemiology, Harvard School of Public Health, Boston, Massachusetts, United States of America, 2 Department of Population and International Health and Department of Environmental Health, Harvard School of Public Health, Boston, Massachusetts, United States of America, 3 Division of Social Medicine and Health Inequalities, Brigham and Women’s Hospital, Boston, Massachusetts, United States of America, 4 Infectious Disease Unit, Massachusetts General Hospital, Boston, Massachusetts, United States of America Funding: This review was supported by The International Union Against ABSTRACT Tuberculosis and Lung Disease through a grant from the World Bank. The funders had no role in Background study design, data collection and analysis, decision to publish, or Tobacco smoking, passive smoking, and indoor air pollution from biomass fuels have been preparation of the manuscript. implicated as risk factors for tuberculosis (TB) infection, disease, and death. Tobacco smoking Competing Interests: The authors and indoor air pollution are persistent or growing exposures in regions where TB poses a major have declared that no competing health risk. We undertook a systematic review and meta-analysis to quantitatively assess the interests exist. association between these exposures and the risk of infection, disease, and death from TB. Academic Editor: Thomas E. Novotny, Center for Tobacco Control Research and Education, United Methods and Findings States of America We conducted a systematic review and meta-analysis of observational studies reporting Citation: Lin HH, Ezzati M, Murray M effect estimates and 95% confidence intervals on how tobacco smoking, passive smoke (2007) Tobacco smoke, indoor air exposure, and indoor air pollution are associated with TB.
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