Young Scientists Represent the Future Of
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Board of Governors Chair Vice Chair Treasurer NANCY ZIMPHER PAUL WALKER ROBERT CATELL President [ex officio] Secretary [ex officio] Fall 2014 ELLIS RUBINSTEIN LARRY SMITH Governors LEN BLAVATNIK ELAINE FUCHS MEHMOOD KHAN FRANK WILCZEK MARY BRABECK ALICE P. GAST JEFFREY D. SACHS DEREK YACH NANCY CANTOR BRIAN GREENE KATHE A. SACKLER MICHAEL ZIGMAN MARTIN CHALFIE THOMAS L. HARRISON MORTIMER D.A. SACKLER MILTON COFIELD THOMAS C. JACKSON GEORGE E. THIBAULT KENNETH L. DAVIS BETH JACOBS PAUL WALKER MIKAEL DOLSTEN JOHN E. KELLY III IRIS WEINSHALL International Governors Chairman Emeriti Honorary Life Governors SETH F. BERKLEY TONI HOOVER JOHN E. SEXTON KAREN E. BURKE MANUEL CAMACHO SOLIS RAJENDRA K. PACHAURI TORSTEN N. WIESEL JOHN F. NIBLACK GERALD CHAN RUSSELL READ S. KRIS GOPALAKRISHNAN PAUL STOFFELS President’s Council PETER AGRE AARON CIECHANOVER GREGORY LUCIER ELLIOTT SIGAL Nobel Laureate & Univ. Nobel Laureate & Former Chairman and CEO, CSO, Bristol-Myers Squibb Prof. and Director, Johns Distinguished Research Prof., Life Technologies Corp MICHAEL SOHLMAN Hopkins Malaria Research Tumor and Vascular Biology RODERICK MACKINNON Former Exec. Director, The Inst., Dept. Molecular Research Center, Faculty of Nobel Laureate & John Nobel Foundation Microbiology and Medicine, Technion-Israel D. Rockefeller, Jr. Prof., PAUL STOFFELS Immunology, Bloomberg Inst. of Tech., Haifa, Israel The Rockefeller Univ.; CSO, Johnson & Johnson; School of Public Health PETER DOHERTY Investigator, HHMI Worldwide Co-Chairman, contentsColumns RICHARD AXEL Nobel Laureate & GERALD J. MCDOUGALL Pharmaceuticals Group Academy Interview Nobel Laureate & Researcher, St. Jude National Partner, Global MARC TESSIER-LAVIGNE Letter from the President 10 Professor, Columbia Univ.; Children’s Research Pharmaceutical & Health President, The Rockefeller Univ. 2 Big Data Download Investigator, HHMI Hospital, Memphis, TN; Sciences Practice, MARY ANN TIGHE The Dream Scenario: Science as a DAVID BALTIMORE Univ. of Melbourne PricewaterhouseCoopers CEO, New York Tri-State The Academy catches up with 2013 Blavatnik Awards winner David Blei. Nobel Laureate & President MIKAEL DOLSTEN LLP Region, CB Richard Ellis Executive Editor Community Emeritus, Caltech President, Worldwide RICHARD MENSCHEL SHIRLEY TILGHMAN ETIENNE-EMILE BAULIEU Research and Development; Sr. Director, Goldman Sachs President Emerita and Diana Friedman Former President, French Sr. VP, Pfizer Inc RONAY MENSCHEL Prof. of Molecular Biology, 4 Inside the Academy Cover Story Academy of Sciences MARCELO EBRARD Chairman of the Board, Princeton Univ. Guest Editor News about Academy programs 12 PAUL BERG CASAUBÓN Phipps Houses; Board of XAVIER TRIAS An Ode to the Power and Beauty of Nobel Laureate & Prof. Mayor, Mexico City Overseers, Weill Cornell Mayor of Barcelona Hallie Kapner and activities Emeritus, Dept. of EDMOND H. FISCHER Medical College FRANK WALSH Biochemistry, Stanford Univ. Nobel Laureate & Prof. HEATHER CEO, Ossianix, Inc. Science LEN BLAVATNIK Emeritus, Dept. of MUNROE-BLOOM GERALD WEISSMANN Design 6 Academy eBriefings Failure is no match for the first recipients of the Blavatnik National Awards Chairman, Access Industries Biochemistry, Univ. of Principal (Pres.) Emerita / Prof. of Medicine, NYU GÜNTER BLOBEL Washington Prof. of Medicine, McGill School of Medicine Strong Studio NYC LLC Summaries of recent eBriefings for Young Scientists, whose boundary-breaking work is shaping the future. Nobel Laureate & Director, JEROME I. FRIEDMAN Univ. JOHN WHITEHEAD Matthew Strong, Adam O’Reilly Laboratory for Cell Biology, Nobel Laureate & Institute FERID MURAD Former Chairman, Lower The Rockefeller Univ. Prof. & Prof. of Physics, Nobel Laureate & Director, Manhattan Development 22 Annals Highlights Op-Ed IRINA BOKOVA Emeritus, MIT IMM Center for Cell Corp.; former Co-Chairman Contributors Recent and upcoming Annals 15 Director General, United JOSEPH GOLDSTEIN Signaling, The University of of Goldman Sachs What Does it Take to Win the Blavatnik Nations Educational, Nobel Laureate & Chairman, Texas at Houston GEORGE WHITESIDES W.M. Akers, David Alvaro, volumes Scientific and Cultural Molecular Genetics, Univ. JOHN F. NIBLACK Woodford L. & Ann A. Award? Organization (UNESCO) of Texas Southwestern Former President, Pfizer Flowers Univ. Prof., Harvard Marina Blinova, Mercedes Gorre, SYDNEY BRENNER Medical Center Global Research & Univ. Daniel Krieger 26 Calendar Common threads of excellence unite this group of young scientists. Nobel Laureate & S. GOPALAKRISHNAN Development TORSTEN N. WIESEL Distinguished Prof., Salk Inst. Exec. Co-Chairman of the PAUL NURSE Nobel Laureate & former Upcoming Academy conferences MICHAEL S. BROWN Board, Infosys Technologies Nobel Laureate & President, Secy. General, Human Editorial Office and meetings Donor Profile Nobel Laureate & Prof. of Limited The Royal Society; former Frontier Science Program 18 Molecular Genetics, Univ. PAUL GREENGARD President, The Rockefeller Organization; President 7 World Trade Center A Caring Hand for Tomorrow’s Leaders of Texas Southwestern Nobel Laureate & Prof. Univ. Emeritus, The Rockefeller 28 Member News 250 Greenwich St, 40th Fl How Len Blavatnik is leveraging his success to help young scientists change Medical Center of Molecular & Cellular RICHARD ROBERTS Univ. Awards, appointments, and LINDA BUCK Neuroscience, The Nobel Laureate & CSO, FRANK WILCZEK New York, NY 10007-2157 the world. Nobel Laureate & Rockefeller Univ. New England Biolabs Nobel Laureate & Herman Phone: 212.298.8645 announcements about Academy Investigator for HHMI; GLENDA GREENWALD EDWARD F. ROVER Feshbach Professor of member of the Fred President, Aspen Brain President, The Dana Physics, MIT Fax: 212.298.3655 members Hutchinson Cancer Forum Foundation Foundation ERNST-LUDWIG Email: [email protected] Member Memoir Research Center PETER GRUSS F. SHERWOOD ROWLAND WINNACKER 23 KAREN E. BURKE President, Max Planck Nobel Laureate & Prof. of Secy. General, Human Portrait of a Scientist Dermatologist & Research Gesellschaft, Germany Chemistry & Earth Science, Frontier Science Program; Membership & Annals Orders Scientist WILLIAM A. HASELTINE Univ. of California, Irvine former Secy. General, Geneticist and developmental biologist Antonio Giraldez investigates where MARCELO EBRARD President, The Haseltine BENGT SAMUELSSON European Research Council; Phone: 212.298.8640 human life begins. CASAUBON Foundation for Medical Nobel Laureate & Prof., former President, Deutsche Fax: 212.298.3650 Former Mayor, Mexico City Sciences and the Arts; Medical & Physiological Forschungsgemeinschaft, THOMAS R. CECH Chairman, Haseltine Global Chem., Karolinska Inst.; Germany Email: [email protected] Nobel Laureate & Health, LLC former Chairman, The ANDREW WITTY Distinguished Prof., Univ. of ERIC KANDEL Nobel Foundation CEO, GlaxoSmithKline Colorado, Boulder Nobel Laureate & Prof., IVAN SEIDENBERG TAN SRI ZAKRI ABDUL Advertising Inquiries MARTIN CHALFIE Physiology & Cell Biology, Advisory Partner, Perella HAMID Nobel Laureate & Univ. Columbia Univ. Weinberg Partners LP; former Science Advisor to the Phone: 212.298.8636 Prof., Dept. of Biological KIYOSHI KUROKAWA Chairman of the Board, Verizon Prime Minister of Malaysia Email: [email protected] Sciences, Columbia Univ. Former Science Advisor to ISMAIL SERAGELDIN ELIAS ZERHOUNI CECILIA CHAN the Prime Minister of Japan; Director, Bibliotheca President, Global Managing Director, Gold Prof., National Graduate Alexandrina, The Library of Research & Development, Visit the Academy online Avenue Ltd. Institute for Policy Studies Alexandria, Egypt Sanofi-Aventis (GRIPS) PHILLIP A. SHARP AHMED ZEWAIL www.nyas.org LEON LEDERMAN Nobel Laureate & Director, Nobel Laureate & Linus Nobel Laureate & Pritzker McGovern Inst., MIT Center Pauling Chair of Chemistry Prof. of Science, Illinois for Cancer Research and Physics, Caltech Inst. of Tech.; Resident GUANGZHAO ZHOU Scholar, Illinois Math & Former Chairman, Chinese Science Academy Association of Science & Technology Letter from the President The Dream Scenario: Science as a Community The New York Academy of Sciences Neuroscience Conferences n a world that can seem dispiriting Regional Awards for Young Scientists, ored individuals, but businessmen, young September 30, 2014 October 10, 2014 every time one opens the newspa- Len looked at our extraordinary cadre people, anyone and everyone. SEPT OCT per, nothing is more welcome than of winners and finalists—now Academy The Academy’s third century begins in Elucidating GPCR New Frontiers in the Ia small proof that people are generous of members, MacArthur Fellows, and much just two short years, and we have expand- 2014 Functional Selectivity: 2014 Neurobiology of Mental heart. So when we see a splendid instance more—and decided to go national with ed our founding goal to a global scale in Novel Opportunities for Illness of this in the world of science, we appreci- an unprecedented, unrestricted award of an extraordinary way. The scientific com- ate it all the more. $250,000 for each of three winners. munity has always prided itself on two Drug Development This issue is devoted to the inaugu- This was not merely generous—it was characteristics—that politics couldn’t Free Event – Advance Registration Required ral recipients of the National Blavatnik visionary. In addition to furthering the hinder person-to-person interactions, Platinum Sponsors: This symposium is supported by Awards for Young Scientists. In itself, this work of some of the brightest young sci- and that the greatest