Young Scientists Represent the Future Of

Total Page:16

File Type:pdf, Size:1020Kb

Young Scientists Represent the Future Of Board of Governors Chair Vice Chair Treasurer NANCY ZIMPHER PAUL WALKER ROBERT CATELL President [ex officio] Secretary [ex officio] Fall 2014 ELLIS RUBINSTEIN LARRY SMITH Governors LEN BLAVATNIK ELAINE FUCHS MEHMOOD KHAN FRANK WILCZEK MARY BRABECK ALICE P. GAST JEFFREY D. SACHS DEREK YACH NANCY CANTOR BRIAN GREENE KATHE A. SACKLER MICHAEL ZIGMAN MARTIN CHALFIE THOMAS L. HARRISON MORTIMER D.A. SACKLER MILTON COFIELD THOMAS C. JACKSON GEORGE E. THIBAULT KENNETH L. DAVIS BETH JACOBS PAUL WALKER MIKAEL DOLSTEN JOHN E. KELLY III IRIS WEINSHALL International Governors Chairman Emeriti Honorary Life Governors SETH F. BERKLEY TONI HOOVER JOHN E. SEXTON KAREN E. BURKE MANUEL CAMACHO SOLIS RAJENDRA K. PACHAURI TORSTEN N. WIESEL JOHN F. NIBLACK GERALD CHAN RUSSELL READ S. KRIS GOPALAKRISHNAN PAUL STOFFELS President’s Council PETER AGRE AARON CIECHANOVER GREGORY LUCIER ELLIOTT SIGAL Nobel Laureate & Univ. Nobel Laureate & Former Chairman and CEO, CSO, Bristol-Myers Squibb Prof. and Director, Johns Distinguished Research Prof., Life Technologies Corp MICHAEL SOHLMAN Hopkins Malaria Research Tumor and Vascular Biology RODERICK MACKINNON Former Exec. Director, The Inst., Dept. Molecular Research Center, Faculty of Nobel Laureate & John Nobel Foundation Microbiology and Medicine, Technion-Israel D. Rockefeller, Jr. Prof., PAUL STOFFELS Immunology, Bloomberg Inst. of Tech., Haifa, Israel The Rockefeller Univ.; CSO, Johnson & Johnson; School of Public Health PETER DOHERTY Investigator, HHMI Worldwide Co-Chairman, contentsColumns RICHARD AXEL Nobel Laureate & GERALD J. MCDOUGALL Pharmaceuticals Group Academy Interview Nobel Laureate & Researcher, St. Jude National Partner, Global MARC TESSIER-LAVIGNE Letter from the President 10 Professor, Columbia Univ.; Children’s Research Pharmaceutical & Health President, The Rockefeller Univ. 2 Big Data Download Investigator, HHMI Hospital, Memphis, TN; Sciences Practice, MARY ANN TIGHE The Dream Scenario: Science as a DAVID BALTIMORE Univ. of Melbourne PricewaterhouseCoopers CEO, New York Tri-State The Academy catches up with 2013 Blavatnik Awards winner David Blei. Nobel Laureate & President MIKAEL DOLSTEN LLP Region, CB Richard Ellis Executive Editor Community Emeritus, Caltech President, Worldwide RICHARD MENSCHEL SHIRLEY TILGHMAN ETIENNE-EMILE BAULIEU Research and Development; Sr. Director, Goldman Sachs President Emerita and Diana Friedman Former President, French Sr. VP, Pfizer Inc RONAY MENSCHEL Prof. of Molecular Biology, 4 Inside the Academy Cover Story Academy of Sciences MARCELO EBRARD Chairman of the Board, Princeton Univ. Guest Editor News about Academy programs 12 PAUL BERG CASAUBÓN Phipps Houses; Board of XAVIER TRIAS An Ode to the Power and Beauty of Nobel Laureate & Prof. Mayor, Mexico City Overseers, Weill Cornell Mayor of Barcelona Hallie Kapner and activities Emeritus, Dept. of EDMOND H. FISCHER Medical College FRANK WALSH Biochemistry, Stanford Univ. Nobel Laureate & Prof. HEATHER CEO, Ossianix, Inc. Science LEN BLAVATNIK Emeritus, Dept. of MUNROE-BLOOM GERALD WEISSMANN Design 6 Academy eBriefings Failure is no match for the first recipients of the Blavatnik National Awards Chairman, Access Industries Biochemistry, Univ. of Principal (Pres.) Emerita / Prof. of Medicine, NYU GÜNTER BLOBEL Washington Prof. of Medicine, McGill School of Medicine Strong Studio NYC LLC Summaries of recent eBriefings for Young Scientists, whose boundary-breaking work is shaping the future. Nobel Laureate & Director, JEROME I. FRIEDMAN Univ. JOHN WHITEHEAD Matthew Strong, Adam O’Reilly Laboratory for Cell Biology, Nobel Laureate & Institute FERID MURAD Former Chairman, Lower The Rockefeller Univ. Prof. & Prof. of Physics, Nobel Laureate & Director, Manhattan Development 22 Annals Highlights Op-Ed IRINA BOKOVA Emeritus, MIT IMM Center for Cell Corp.; former Co-Chairman Contributors Recent and upcoming Annals 15 Director General, United JOSEPH GOLDSTEIN Signaling, The University of of Goldman Sachs What Does it Take to Win the Blavatnik Nations Educational, Nobel Laureate & Chairman, Texas at Houston GEORGE WHITESIDES W.M. Akers, David Alvaro, volumes Scientific and Cultural Molecular Genetics, Univ. JOHN F. NIBLACK Woodford L. & Ann A. Award? Organization (UNESCO) of Texas Southwestern Former President, Pfizer Flowers Univ. Prof., Harvard Marina Blinova, Mercedes Gorre, SYDNEY BRENNER Medical Center Global Research & Univ. Daniel Krieger 26 Calendar Common threads of excellence unite this group of young scientists. Nobel Laureate & S. GOPALAKRISHNAN Development TORSTEN N. WIESEL Distinguished Prof., Salk Inst. Exec. Co-Chairman of the PAUL NURSE Nobel Laureate & former Upcoming Academy conferences MICHAEL S. BROWN Board, Infosys Technologies Nobel Laureate & President, Secy. General, Human Editorial Office and meetings Donor Profile Nobel Laureate & Prof. of Limited The Royal Society; former Frontier Science Program 18 Molecular Genetics, Univ. PAUL GREENGARD President, The Rockefeller Organization; President 7 World Trade Center A Caring Hand for Tomorrow’s Leaders of Texas Southwestern Nobel Laureate & Prof. Univ. Emeritus, The Rockefeller 28 Member News 250 Greenwich St, 40th Fl How Len Blavatnik is leveraging his success to help young scientists change Medical Center of Molecular & Cellular RICHARD ROBERTS Univ. Awards, appointments, and LINDA BUCK Neuroscience, The Nobel Laureate & CSO, FRANK WILCZEK New York, NY 10007-2157 the world. Nobel Laureate & Rockefeller Univ. New England Biolabs Nobel Laureate & Herman Phone: 212.298.8645 announcements about Academy Investigator for HHMI; GLENDA GREENWALD EDWARD F. ROVER Feshbach Professor of member of the Fred President, Aspen Brain President, The Dana Physics, MIT Fax: 212.298.3655 members Hutchinson Cancer Forum Foundation Foundation ERNST-LUDWIG Email: [email protected] Member Memoir Research Center PETER GRUSS F. SHERWOOD ROWLAND WINNACKER 23 KAREN E. BURKE President, Max Planck Nobel Laureate & Prof. of Secy. General, Human Portrait of a Scientist Dermatologist & Research Gesellschaft, Germany Chemistry & Earth Science, Frontier Science Program; Membership & Annals Orders Scientist WILLIAM A. HASELTINE Univ. of California, Irvine former Secy. General, Geneticist and developmental biologist Antonio Giraldez investigates where MARCELO EBRARD President, The Haseltine BENGT SAMUELSSON European Research Council; Phone: 212.298.8640 human life begins. CASAUBON Foundation for Medical Nobel Laureate & Prof., former President, Deutsche Fax: 212.298.3650 Former Mayor, Mexico City Sciences and the Arts; Medical & Physiological Forschungsgemeinschaft, THOMAS R. CECH Chairman, Haseltine Global Chem., Karolinska Inst.; Germany Email: [email protected] Nobel Laureate & Health, LLC former Chairman, The ANDREW WITTY Distinguished Prof., Univ. of ERIC KANDEL Nobel Foundation CEO, GlaxoSmithKline Colorado, Boulder Nobel Laureate & Prof., IVAN SEIDENBERG TAN SRI ZAKRI ABDUL Advertising Inquiries MARTIN CHALFIE Physiology & Cell Biology, Advisory Partner, Perella HAMID Nobel Laureate & Univ. Columbia Univ. Weinberg Partners LP; former Science Advisor to the Phone: 212.298.8636 Prof., Dept. of Biological KIYOSHI KUROKAWA Chairman of the Board, Verizon Prime Minister of Malaysia Email: [email protected] Sciences, Columbia Univ. Former Science Advisor to ISMAIL SERAGELDIN ELIAS ZERHOUNI CECILIA CHAN the Prime Minister of Japan; Director, Bibliotheca President, Global Managing Director, Gold Prof., National Graduate Alexandrina, The Library of Research & Development, Visit the Academy online Avenue Ltd. Institute for Policy Studies Alexandria, Egypt Sanofi-Aventis (GRIPS) PHILLIP A. SHARP AHMED ZEWAIL www.nyas.org LEON LEDERMAN Nobel Laureate & Director, Nobel Laureate & Linus Nobel Laureate & Pritzker McGovern Inst., MIT Center Pauling Chair of Chemistry Prof. of Science, Illinois for Cancer Research and Physics, Caltech Inst. of Tech.; Resident GUANGZHAO ZHOU Scholar, Illinois Math & Former Chairman, Chinese Science Academy Association of Science & Technology Letter from the President The Dream Scenario: Science as a Community The New York Academy of Sciences Neuroscience Conferences n a world that can seem dispiriting Regional Awards for Young Scientists, ored individuals, but businessmen, young September 30, 2014 October 10, 2014 every time one opens the newspa- Len looked at our extraordinary cadre people, anyone and everyone. SEPT OCT per, nothing is more welcome than of winners and finalists—now Academy The Academy’s third century begins in Elucidating GPCR New Frontiers in the Ia small proof that people are generous of members, MacArthur Fellows, and much just two short years, and we have expand- 2014 Functional Selectivity: 2014 Neurobiology of Mental heart. So when we see a splendid instance more—and decided to go national with ed our founding goal to a global scale in Novel Opportunities for Illness of this in the world of science, we appreci- an unprecedented, unrestricted award of an extraordinary way. The scientific com- ate it all the more. $250,000 for each of three winners. munity has always prided itself on two Drug Development This issue is devoted to the inaugu- This was not merely generous—it was characteristics—that politics couldn’t Free Event – Advance Registration Required ral recipients of the National Blavatnik visionary. In addition to furthering the hinder person-to-person interactions, Platinum Sponsors: This symposium is supported by Awards for Young Scientists. In itself, this work of some of the brightest young sci- and that the greatest
Recommended publications
  • RANDY SCHEKMAN Department of Molecular and Cell Biology, Howard Hughes Medical Institute, University of California, Berkeley, USA
    GENES AND PROTEINS THAT CONTROL THE SECRETORY PATHWAY Nobel Lecture, 7 December 2013 by RANDY SCHEKMAN Department of Molecular and Cell Biology, Howard Hughes Medical Institute, University of California, Berkeley, USA. Introduction George Palade shared the 1974 Nobel Prize with Albert Claude and Christian de Duve for their pioneering work in the characterization of organelles interrelated by the process of secretion in mammalian cells and tissues. These three scholars established the modern field of cell biology and the tools of cell fractionation and thin section transmission electron microscopy. It was Palade’s genius in particular that revealed the organization of the secretory pathway. He discovered the ribosome and showed that it was poised on the surface of the endoplasmic reticulum (ER) where it engaged in the vectorial translocation of newly synthesized secretory polypeptides (1). And in a most elegant and technically challenging investigation, his group employed radioactive amino acids in a pulse-chase regimen to show by autoradiograpic exposure of thin sections on a photographic emulsion that secretory proteins progress in sequence from the ER through the Golgi apparatus into secretory granules, which then discharge their cargo by membrane fusion at the cell surface (1). He documented the role of vesicles as carriers of cargo between compartments and he formulated the hypothesis that membranes template their own production rather than form by a process of de novo biogenesis (1). As a university student I was ignorant of the important developments in cell biology; however, I learned of Palade’s work during my first year of graduate school in the Stanford biochemistry department.
    [Show full text]
  • Unrestricted Immigration and the Foreign Dominance Of
    Unrestricted Immigration and the Foreign Dominance of United States Nobel Prize Winners in Science: Irrefutable Data and Exemplary Family Narratives—Backup Data and Information Andrew A. Beveridge, Queens and Graduate Center CUNY and Social Explorer, Inc. Lynn Caporale, Strategic Scientific Advisor and Author The following slides were presented at the recent meeting of the American Association for the Advancement of Science. This project and paper is an outgrowth of that session, and will combine qualitative data on Nobel Prize Winners family histories along with analyses of the pattern of Nobel Winners. The first set of slides show some of the patterns so far found, and will be augmented for the formal paper. The second set of slides shows some examples of the Nobel families. The authors a developing a systematic data base of Nobel Winners (mainly US), their careers and their family histories. This turned out to be much more challenging than expected, since many winners do not emphasize their family origins in their own biographies or autobiographies or other commentary. Dr. Caporale has reached out to some laureates or their families to elicit that information. We plan to systematically compare the laureates to the population in the US at large, including immigrants and non‐immigrants at various periods. Outline of Presentation • A preliminary examination of the 609 Nobel Prize Winners, 291 of whom were at an American Institution when they received the Nobel in physics, chemistry or physiology and medicine • Will look at patterns of
    [Show full text]
  • CRISPR-Cas9 a New Tool for Genome Editing.Pdf
    CRICRICRISSPSPEPERERRCCCaasas9s99 AA ANe Ne Neww wT To Toool olf olf orf orGe rGe Gennonomomem eE eEd Editdiitinitngingg ByB JyBen Jyen Jneninferinfer iDofer Do uDodunduand,a nK, aeK,v eKivnei nvDi noD xoDzxoezxnez,n ea,n a,d na dMn dMa rMatirnati rnJti nJie nJkienkek A AK eAKy eK yEe xEyp xEepxrepimreimenriment enpt rpto rpdorudocudecudec dbe ydb Tyb hTye hT eEh xeEp xElpoxlrpoelrore’srre ’Gsr ’uGs iuGdieud ietdo et oB t ioBo ilBooilgooylgoygy 2 The Explorer’s Guide to Biology https://explorebiology.org/ CRISPR-Cas9 A New Tool for Genome Editing Jennifer Doudna, Kevin Doxzen, and Martin Jinek Jennifer Doudna Jennifer Doudna is a professor in the Departments of Molecular and Cell Biology and the Chemistry and Chemical Engineering at the University of California, Berkeley. For her studies on CRISPR-Cas9, Dr. Doudna has received several awards including the Breakthrough Prize in the Life Sciences, the Japan Prize, and the Canada Gairdner Award. She has been leading efforts to discuss ethical uses of genome editing technologies. Doudna teaches in Bio 1A, an introductory biology class at UC Berkeley. Kevin Doxzen Kevin Doxzen, a former graduate student with Jennifer Doudna, is a sci- ence communications specialist at the Innovative Genomics Institute, which is advancing genome engineering using CRISPR technologies. 3 Martin Jinek Martin Jinek, born in Czechoslovakia and a former postdoctoral fellow with Jennifer Doudna, is now an associate professor in the Department of Biochemistry at the University of Zurich. Jinek received the EMBL John Kendrew Young Scientist Award and the Friedrich Miescher Award of the Swiss Society for Molecular and Cellular Biosciences.
    [Show full text]
  • Download This Issue As A
    MICHAEL GERRARD ‘72 COLLEGE HONORS FIVE IS THE GURU OF DISTINGUISHED ALUMNI CLIMATE CHANGE LAW WITH JOHN JAY AWARDS Page 26 Page 18 Columbia College May/June 2011 TODAY Nobel Prize-winner Martin Chalfie works with College students in his laboratory. APassion for Science Members of the College’s science community discuss their groundbreaking research ’ll meet you for a I drink at the club...” Meet. Dine. Play. Take a seat at the newly renovated bar grill or fine dining room. See how membership in the Columbia Club could fit into your life. For more information or to apply, visit www.columbiaclub.org or call (212) 719-0380. The Columbia University Club of New York 15 West 43 St. New York, N Y 10036 Columbia’s SocialIntellectualCulturalRecreationalProfessional Resource in Midtown. Columbia College Today Contents 26 20 30 18 73 16 COVER STORY ALUMNI NEWS DEPARTMENTS 2 20 A PA SSION FOR SCIENCE 38 B OOKSHELF LETTERS TO THE Members of the College’s scientific community share Featured: N.C. Christopher EDITOR Couch ’76 takes a serious look their groundbreaking work; also, a look at “Frontiers at The Joker and his creator in 3 WITHIN THE FA MILY of Science,” the Core’s newest component. Jerry Robinson: Ambassador of By Ethan Rouen ’04J, ’11 Business Comics. 4 AROUND THE QU A DS 4 Reunion, Dean’s FEATURES 40 O BITU A RIES Day 2011 6 Class Day, 43 C L A SS NOTES JOHN JA Y AW A RDS DINNER FETES FIVE Commencement 2011 18 The College honored five alumni for their distinguished A LUMNI PROFILES 8 Senate Votes on ROTC professional achievements at a gala dinner in March.
    [Show full text]
  • Nobel Laureates Endorse Joe Biden
    Nobel Laureates endorse Joe Biden 81 American Nobel Laureates in Physics, Chemistry, and Medicine have signed this letter to express their support for former Vice President Joe Biden in the 2020 election for President of the United States. At no time in our nation’s history has there been a greater need for our leaders to appreciate the value of science in formulating public policy. During his long record of public service, Joe Biden has consistently demonstrated his willingness to listen to experts, his understanding of the value of international collaboration in research, and his respect for the contribution that immigrants make to the intellectual life of our country. As American citizens and as scientists, we wholeheartedly endorse Joe Biden for President. Name Category Prize Year Peter Agre Chemistry 2003 Sidney Altman Chemistry 1989 Frances H. Arnold Chemistry 2018 Paul Berg Chemistry 1980 Thomas R. Cech Chemistry 1989 Martin Chalfie Chemistry 2008 Elias James Corey Chemistry 1990 Joachim Frank Chemistry 2017 Walter Gilbert Chemistry 1980 John B. Goodenough Chemistry 2019 Alan Heeger Chemistry 2000 Dudley R. Herschbach Chemistry 1986 Roald Hoffmann Chemistry 1981 Brian K. Kobilka Chemistry 2012 Roger D. Kornberg Chemistry 2006 Robert J. Lefkowitz Chemistry 2012 Roderick MacKinnon Chemistry 2003 Paul L. Modrich Chemistry 2015 William E. Moerner Chemistry 2014 Mario J. Molina Chemistry 1995 Richard R. Schrock Chemistry 2005 K. Barry Sharpless Chemistry 2001 Sir James Fraser Stoddart Chemistry 2016 M. Stanley Whittingham Chemistry 2019 James P. Allison Medicine 2018 Richard Axel Medicine 2004 David Baltimore Medicine 1975 J. Michael Bishop Medicine 1989 Elizabeth H. Blackburn Medicine 2009 Michael S.
    [Show full text]
  • The Nobel Foundation Annual Review 2018
    THE NOBEL FOUNDATION ANNUAL REVIEW • 2018 THE NOBEL FOUNDATION · ANNUAL REVIEW 2018 1 1901 WILHELM CONRAD RÖNTGEN The first Nobel Prize in Physics was awarded to Wilhelm Conrad Röntgen for his discovery of X-radiation. The X-ray tube pictured on the cover is on display at the Nobel Prize Museum. Photo: Alexander Mahmoud 2018 BERNICE A. KING “I wish to commend the Nobel Museum for (…) this new exhibition. I believe that my parents’ message of social justice and equality is as important today as ever before.” The exhibition A Right to Freedom - Martin Luther King, Jr. was inaugurated by King’s daughter Bernice A. King at the Nobel Prize Museum on 28 September 2018. Photo: Alexander Mahmoud 2 THE NOBEL FOUNDATION · ANNUAL REVIEW 2018 THE NOBEL FOUNDATION · ANNUAL REVIEW 2018 3 For the greatest beneft to humankind ALFRED NOBEL 4 THE NOBEL FOUNDATION · ANNUAL REVIEW 2018 “I can tell you how. It is very easy. The first thing you must do is to have great teachers.” Paul A. Samuelson, 1970 Laureate in Economic Sciences, on how to earn a Nobel Prize. obel Laureates often Luther King, Jr., and with a Nobel Prize attest to how crucial Teacher Summit on the theme Teach their teachers have been. Love and Understanding, with 350 Teachers, researchers and teachers from 15 countries attending. others who contribute Al Gore, the 2007 Peace Prize Lars Heikensten, Executive Director Nto increased knowledge are the heroes Laureate, addressed How to Solve the of the Nobel Foundation since 2011. and heroines of our age. When the very Climate Crisis when he spoke at the 2018 Photo: Kari Kohvakka idea of science is being questioned, our Nobel Peace Prize Forum in Oslo.
    [Show full text]
  • Randy W. Schekman, Phd
    Randy W. Schekman, PhD Current Position Professor of molecular and cell biology at the University of California, Berkeley Investigator at the Howard Hughes Medical Institute Editor-in-Chief, eLIFE Journal Education BA, molecular biology, University of California, Los Angeles PhD, biochemistry, Stanford University Awards Nobel Prize in Physiology or Medicine 2013 (shared with James E. Rothman and Thomas C. Südhof ) Albert Lasker Award for Basic Medical Research Eli Lilly Research Award in Microbiology and Immunology Lewis S. Rosenstiel Award in Basic Biomedical Science, Brandeis University Gairdner Foundation International Award Louisa Gross Horwitz Prize, Columbia University 2008 Dickson Prize in Medicine, University of Pittsburgh E.B. Wilson Medal, American Society for Cell Biology Memberships US National Academy of Sciences American Academy of Arts and Sciences American Society of Cell Biology American Association for the Advancement of Science American Philosophical Society Biography Traffic inside a cell is as complicated as rush hour near any metropolitan area. But drivers know how to follow the signs and roadways to reach their destinations. How do different cellular proteins "read" molecular signposts to find their way inside or outside of a cell? For the past three decades, Randy Schekman has been characterizing the traffic drivers that shuttle cellular proteins as they move in membrane-bound sacs, or vesicles, within a cell. His detailed elucidation of cellular travel patterns has provided fundamental knowledge about cells and has enhanced understanding of diseases that arise when bottlenecks impede some of the protein flow. His work earned him one of the most prestigious prizes in science, the 2002 Albert Lasker Award for Basic Medical Research, which he shared with James Rothman.
    [Show full text]
  • The 2009 Lindau Nobel Laureate Meeting: Roger Y. Tsien, Chemistry 2008
    Journal of Visualized Experiments www.jove.com Video Article The 2009 Lindau Nobel Laureate Meeting: Roger Y. Tsien, Chemistry 2008 Roger Y. Tsien1 1 URL: https://www.jove.com/video/1575 DOI: doi:10.3791/1575 Keywords: Cellular Biology, Issue 35, GFP, Green Fluorescent Protein, IFPs, jellyfish, PKA, Calmodulin Date Published: 1/13/2010 Citation: Tsien, R.Y. The 2009 Lindau Nobel Laureate Meeting: Roger Y. Tsien, Chemistry 2008. J. Vis. Exp. (35), e1575, doi:10.3791/1575 (2010). Abstract American biochemist Roger Tsien shared the 2008 Nobel Prize in Chemistry with Martin Chalfie and Osamu Shimomura for their discovery and development of the Green Fluorescent Protein (GFP). Tsien, who was born in New York in 1952 and grew up in Livingston New Jersey, began to experiment in the basement of the family home at a young age. From growing silica gardens of colorful crystallized metal salts to attempting to synthesize aspirin, these early experiments fueled what would become Tsien's lifelong interest in chemistry and colors. Tsien's first official laboratory experience was an NSF-supported summer research program in which he used infrared spectroscopy to examine how metals bind to thiocyanate, for which he was awarded a $10,000 scholarship in the Westinghouse Science Talent Search. Following graduation from Harvard in 1972, Tsien attended Cambridge University in England under a Marshall Scholarship. There he learned organic chemistry --a subject he'd hated as an undergraduate-- and looked for a way to synthesize dyes for imaging neuronal activity, generating BAPTA based optical calcium indicator dyes. Following the completion of his postdoctoral training at Cambridge in 1982, Tsien accepted a faculty position at the University of California, Berkeley.
    [Show full text]
  • Download Ps Nobel Prizes for Site BEE 11.18.16 Revised 11.30.17.Pdf
    Nobel Laureates at the College of Physicians and Surgeons For years, College of Physicians and Surgeons alumni, faculty, and researchers have led groundbreaking clinical and basic scientific studies that have transformed our understanding of human biology and advanced the practice of medicine. On many occasions, this work has been honored with the Nobel Prize. The scope of research led by P&S Nobel laureates is tremendous. Although most of our prizewinners were honored for work in physiology or medicine, a few also received the prize for chemistry. Their research has fundamentally shaped the course of numerous fields, including cardiology, neuroscience, genetics, pharmaceutical development, and more. Our Nobel laureates include: André Cournand and Dickinson Richards (P&S’23), whose work at P&S on cardiac catheterization—a method of inserting a tiny tube into the heart—provided the basis for open-heart surgery and interventional cardiology Baruch Blumberg (P&S’51), who discovered the hepatitis B virus and helped develop a test and a vaccine for the virus Joshua Lederberg, a Columbia College and P&S graduate student who showed that bacteria can exchange genes when they reproduce, creating a way to model and study genetics in higher organisms Harold Varmus (P&S’66), who demonstrated how genes in normal human and animal cells can mutate to cause cancer, leading to a new generation of research on the genetic origins of cancer Eric Kandel, current University Professor, who showed how memories are stored in nerve cells, greatly enhancing
    [Show full text]
  • Service History July 2012 AGM - September 2018 AGM
    Service History July 2012 AGM - September 2018 AGM The information in this Service History is true and complete to the best of The Society’s knowledge. If you are aware of any errors please let the Governance and Risk Manager know by email: [email protected] Service History Index DATES PAGE # 5 July 2012 – 24 July 2013 Page 1 24 July 2013 – 1 July 2014 Page 14 1 July 2014 – 7 July 2015 Page 28 7 July 2015 – 31 July 2016 Page 42 31 July 2016 – 12 July 2017 Page 60 12 July 2017 – 16 September 2018 Page 82 Service History: July 2012 AGM – Sept 2018 AGM Introduction Up until 2006 the service history of The Society’s members was captured in Grey Books. It was also documented between 1990-2013 in The Society’s old database iMIS, which will be migrated to the CRM member directory adopted in 2016. This document collates missing service history data from July 2012 to September 2018. Grey Books were relaunched as ‘Grey Records’ in 2019 beginning with the period from the September AGM 2018 up until July AGM 2019. There will now be a Grey Record published every year reflecting the previous year’s service history. The Grey Record will now showcase service history from Member Forum to Member Forum (typically held in the Winter). 5 July 2012 – 24 July 2013 Honorary Officers (and Trustees) POSITION NAME President Jonathan Ashmore Deputy President Richard Vaughan-Jones Honorary Treasurer Rod Dimaline Education & Outreach Committee Chair Blair Grubb Meetings Committee Chair David Wyllie Policy Committee Chair Mary Morrell Membership & Grants Committee
    [Show full text]
  • Medicine@Yale U
    @ MedicineAdvancing Biomedical Science, Education and Health Care YaleVolume 4, Issue 3 July/August 2008 Leading scientist is appointed new chair of Cell Biology Membrane traffi c expert and chair of the School of Medicine’s to Yale’s recently protein-coding genes in the human Department of Cell Biology. Roth- opened West Cam- genome, providing fresh insights into will head a department man will come to Yale from Columbia pus in West Haven, disease and new molecular targets for that has shaped the fi eld University’s College of Physicians and Conn., where he will therapy. Under Rothman’s leadership Surgeons, where he is now a professor launch a Center for the Department of Cell Biology will James E. Rothman, F>:, one of the in the Department of Physiology and High-Throughput be signifi cantly expanded, and will be world’s foremost experts on mem- Biophysics, the Clyde and Helen Wu Cell Biology. At the co-located at the West Campus along brane traffi cking, the means by which Professor of Chemical Biology and new center, multi- with its present location at the main proteins and other materials are director of the Columbia Genome +BNFT3PUINBO disciplinary teams campus of the School of Medicine. transported within and between cells, Center. of scientists will develop tools and For his decades of seminal re- has been named the Fergus F. Wal- In addition to directing Cell techniques to rapidly decipher the cel- search on the transport of molecules lace Professor of Biomedical Sciences Biology, Rothman is the fi rst recruit lular functions of the
    [Show full text]
  • Richard Scheller and Thomas Südhof Receive the 2013 Albert Lasker Basic Medical Research Award
    Richard Scheller and Thomas Südhof receive the 2013 Albert Lasker Basic Medical Research Award Jillian H. Hurst J Clin Invest. 2013;123(10):4095-4101. https://doi.org/10.1172/JCI72681. News Neural communication underlies all brain activity. It governs our thoughts, feelings, sensations, and actions. But knowing the importance of neural communication does not answer a central question of neuroscience: how do individual neurons communicate? We know that communication between two neurons occurs at specialized cell junctions called synapses, at which two communicating neurons are separated by the synaptic cleft. The presynaptic neuron releases chemicals, known as neurotransmitters, into the synaptic cleft in which neurotransmitters bind to receptors on the surface of the postsynaptic neuron. Neurotransmitter release occurs in response to an action potential within the sending neuron that induces depolarization of the nerve terminal and causes an influx of calcium. Calcium influx triggers the release of neurotransmitters through a specialized form of exocytosis in which neurotransmitter-filled vesicles fuse with the plasma membrane of the presynaptic nerve terminal in a region known as the active zone, spilling neurotransmitter into the synaptic cleft. By the 1950s, it was clear that brain function depended on chemical neurotransmission; however, the molecular activities that governed neurotransmitter release were virtually unknown until the early 1990s. This year, the Lasker Foundation honors Richard Scheller (Genentech) and Thomas Südhof (Stanford University School of Medicine) for their “discoveries concerning the molecular machinery and regulatory mechanisms that underlie the rapid release of neurotransmitters.” Over the course of two decades, Scheller […] Find the latest version: https://jci.me/72681/pdf News Richard Scheller and Thomas Südhof receive the 2013 Albert Lasker Basic Medical Research Award Neural communication underlies all Setting the stage um-driven action potentials elicited neu- brain activity.
    [Show full text]