Italian Association for the Study of the Liver
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VOLUME 51 SUPPLEMENT 3 October 2019 ISSN 1590-8658 Abstracts of the A.I.S.F. - Italian Association for the Study of the Liver - Monothematic Conference Communication and Cooperation: Clinical Networks in Hepatology Rimini, October 3rd- 4th, 2019 Digestive and Liver Disease An International Journal of Gastroenterology and Hepatology Vol. 51 Supplement 3 (2019) Official Journal of: Italian Association for Hospital Gastroenterologists and Digestive Endoscopists Italian Society of Gastroenterology (SIGE) (AIGO) Italian Society of Pediatric Gastroenterology and Hepatology (SIGENP) Italian Association for the Study of the Liver (AISF) Italian Group for the Study of Infl ammatory Bowel Disease (IG-IBD) Italian Association for the Study of the Pancreas (AISP) Fédération Francophone de Cancérologie Digestive (FFCD) Italian Association for Digestive Endoscopy (SIED) Editors Emeriti Editor-in-Chief Managing Editor Mario Angelico, Rome, Italy Roberto de Franchis, Milan, Italy Silvia Malosio, Milan, Italy Gabriele Bianchi-Porro, Milan, Italy Co-Editors Editorial Assistant Savino Bruno, Milan, Italy Brenda Dionisi, Milan, Italy Silvia Fargion, Milan, Italy Maurizio Vecchi, Milan, Italy ASSOCIATE EDITORS DESIGNATED BY THE AFFILIATED SOCIETIES Carlo Agostoni (SIGENP), Milan, Italy Edoardo Giannini (AISF), Genoa, Italy Franco Radaelli (SIED), Como, Italy Carolina Ciacci (SIGE), Naples, Italy Gioacchino Leandro (AIGO), Castellana Grotte, Italy Fernando Rizzello (IG-IBD), Bologna, Italy Raffaele Pezzilli (AISP), Bologna, Italy SECTION EDITORS Basic Science General Gastroenterology Liver Disease Gianfranco Alpini, Temple, Texas, USA Colm O’Morain, Dublin, Ireland Jaime Bosch, Barcelona, Spain Marcello Chieppa, Castellana Grotte, Italy Ambrogio Orlando, Palermo, Italy Maurizia Brunetto, Pisa, Italy Paola Dongiovanni, Milan, Italy Edoardo Savarino, Padua, Italy Patrizia Burra, Padua, Italy Romina Mancinelli, Rome, Italy Marco Soncini, Milano, Italy Alessandra Dell’Era, Milan, Italy Theresa Pizarro, Cleveland, Ohio, USA Radu Tutuian, Bern, Switzerland Maria Francesca Donato, Milano, Italy Laura Stronati, Rome, Italy Umberto Volta, Bologna, Italy Rafael Esteban Mur, Barcelona, Spain Angelo Zullo, Roma, Italy Anna Fracanzani, Milan, Italy Vincenzo La Mura, San Donato Milanese, Italy Digestive Endoscopy Imaging Ana Lleo, Milan, Italy Andres Cardenas, Barcelona, Spain Valerio Nobili, Rome, Italy Annalisa Berzigotti, Bern, Switzerland Arnulf Ferlitsch, Graz, Austria Salvatore Petta, Palermo, Italy Cristina Bezzio, Garbagnate Milanese, Italy Cesare Hassan, Rome, Italy Fabio Piscaglia, Bologna, Italy Federica Furfaro, Rozzano, Italy Helmut Neumann, Mainz, Germany Ashwani K Singal, Birmingham, AL, USA Emanuele Rondonotti, Como, Italy Giovanni Maconi, Milan, Italy Ilaria Tarantino, Palermo, Italy Pancreatic Disease Rocco Maurizio Zagari, Bologna, Italy Infectious Disease Gabriele Capurso, Rome, Italy Antonella d’Arminio Monforte, Milan, Italy Alberto Malesci, Milan, Italy Digestive Oncology Thomas Aparicio, Bobigny, France Infl ammatory Bowel Disease Pediatric Gastroenterology Salvatore Cucchiara, Rome, Italy Renato Cannizzaro, Aviano, Italy Alessandro Armuzzi, Rome, Italy Côme Lepage, Dijon, France Emma Calabrese, Rome, Italy Surgery Steve Collins, Hamilton, ON, Canada Massimo Falconi, Milan, Italy Peter Lakatos, Budapest, Hungary General Gastroenterology Gianluca Matteo Sampietro, Milan, Italy Massimo Bellini, Pisa, Italy Roberto Santambrogio, Milan, Italy Maura Corsetti, Nottingham, England, UK Liver Disease Nicola de Bortoli, Pisa, Italy Pietro Andreone, Bologna, Italy Statistical Consultant Luca Elli, Milano, Italy Alessia Ciancio, Turin, Italy Federico Ambrogi, Milan, Italy EDITORIAL BOARD Domenico Alvaro, Rome, Italy Stefano Fagiuoli, Bergamo, Italy Massimiliano Mutignani, Milano, Italy Waddah Alrefai, Chicago, Illinois, USA Pietro Familiari, Roma, Italy David Mutimer, Birmingham, UK Angelo Andriulli, Foggia, Italy Massimo Fantini, Rome, Italy Matteo Neri, Milan, Italy Paolo Angeli, Padua, Italy Piero Marco Fisichella, Boston, Massachusetts, USA Mattijs Numans, Leiden, Netherlands Adolfo Francesco Attili, Rome, Italy Heather Francis, Temple, Texas, USA Maria Caterina Parodi, Genoa, Italy Gabrio Bassotti, Perugia, Italy Mirella Fraquelli, Milan, Italy Jean-Marc Phelip, Saint-Etienne, France Laurent Beaugerie, Paris, France Dennis Freshwater, Birmingham, UK Paola Piccolo, Rome, Italy Robert Benamouzig, Bobigny, France Lorenzo Fuccio, Bologna, Italy Antonio Pinna, Bologna, Italy Antonio Benedetti, Ancona, Italy Pietro Fusaroli, Bologna, Italy Massimo Puoti, Milano, Italy Marc Benninga, Amsterdam, Netherlands Armando Gabbrielli, Verona, Italy Alessandro Repici, Milan, Italy Marina Berenguer, Valencia, Spain Giovanni Battista Gaeta, Naples, Italy Oliviero Riggio, Rome, Italy Roman Bogorad, Cambridge, Massachusetts, USA Giuseppe Galloro, Naples, Italy Mario Rizzetto, Turin, Italy Jean-Pierre Bronowicki, Vandoeuvre-les-Nancy, France Antonio Gasbarrini, Rome, Italy Renato Romagnoli, Turin, Italy William Brugge, Boston, Massachusetts, USA Eugenio Gaudio, Rome, Italy Massimo Rugge, Padua, Italy Elisabetta Buscarini, Crema, Italy Shannon Glaser, Temple, Texas, USA Tilman Sauerbruch, Bonn, Germany Carlo Catassi, Ancona, Italy Michael Gschwantler, Vienna, Austria Jean-Cristophe Saurin, Pierre-Bénite, France Umberto Cillo, Padua, Italy Pietro Invernizzi, Milan, Italy Vincenzo Savarino, Genoa, Italy Agostino Colli, Lecco, Italy Robert Jensen, Baltimore, USA Laurent Siproudhis, Rennes, France Rita Conigliaro, Modena, Italy Michel Kahaleh, Charlottesville, New York, USA Etienne Sokal, Brussels, Belgium Dario Conte, Milan, Italy David Laharie, Pessac, France Mario Strazzabosco, New Haven, Connecticut, USA Gino Roberto Corazza, Pavia, Italy René Laugier, Marseille, France Giacomo Carlo Sturniolo, Padua, Italy Enrico Corazziari, Rome, Italy Astrid Lievre, Saint-Cloud, France Pier Alberto Testoni, Milan, Italy Antonio Craxì, Palermo, Italy Patrick Maisonneuve, Milan, Italy Giuseppe Tisone, Rome, Italy Gianfranco Delle Fave, Rome, Italy Gianpiero Manes, Rho, Italy Gian Eugenio Tontini, Milan, Italy Anthony Demetris, Pittsburgh, Pennsylvania, USA Riccardo Marmo, Salerno, Italy Michael Trauner, Vienna, Austria Sharon DeMorrow, Temple, Texas, USA Marco Marzioni, Ancona, Italy Vincenzo Villanacci, Brescia, Italy Philippe Ducrotte, Rouen, France Carlo Merkel, Padova, Italy Frank Zerbib, Bordeaux, France Amal Dutta, Dallas, Texas, USA Filomena Morisco, Naples, Italy Huiping Zhou, Richmond, Virginia, USA Digestive and Liver Disease 51 (2019) e259–e264 Contents lists available at ScienceDirect Digestive and Liver Disease journal homepage: www.elsevier.com/locate/dld Abstracts of the A.I.S.F. – Italian Association for the Study of the Liver – Monothematic Conference “Communication and Cooperation: Clinical Networks in Hepatology” Rimini, October 3rd–4th, 2019 P-01 P-02 New reports of curcumine-induced hepatitis Social and labor market reintegration of the transplanted patient G. Gasbarrini 1, C. Mosoni 1, F. Bonvicini 2 L. Bellis 1, C. Carella 1, M. Trerotola 1, 1 Internal Medicine and Gastroenterology, A. Gemelli L. Lombardini 1, E. Sorrentino 2, R. Melloni 3, Polyclinic IRSCC, Catholic University of Rome, Rome, G. Mosconi 4, G. Sella 5, S. Mosconi 3, Italy G. Sangiorgi 6, C. De Cillia 6, V. Totti 6, 2 School of Medicine, Alma Mater University of M.C. Morelli 7, V. Vero 7, A. Ermolao 8, C. Canali 3, Bologna, Bologna, Italy B. Papaleo 9, A. Nanni Costa 1, M. Cardillo 1 Curcuma is an herbaceous plant of the Zingiberaceae family; it’s 1 Italian National Transplant Centre, Italian National widely used in the south eastern cuisine. And as a spice in the Indian Institute of Health, Rome, Italy cuisine as well. Curcuma is also known as the Saffron of Indies. 2 Safety and Prevention Service, Italian National It is currently believed that this spice stimulates the immune Institute of Health, Rome, Italy system and carries out anti- tumor, anti- oxidant and anti- inflam- 3 Interdepartmental Research Center on Security and matory activity. Security (CRIS), University of Modena and Reggio There is increasing evidence in literature of hepatitis associated Emilia, Modena, Italy with curcuma intake: to date up to ten cases of cholestatic hepatitis 4 Nephrology and Dialysis Units, have been reported. Morgagni-Pierantoni Hospital, AUSL Romagna, Forlì, Recently 4 patients, aged 25–45 years, 3 females and 1 male, Italy referred to our medical observation. Hypertransaminasemia up to 5 Sport Medicine Unit, AUSL Romagna, Ravenna, Italy 3–6 times with respect to normal value, and increasing of gamma- 6 Liver Transplant Centre and Regional Reference GT up to 4–8 times the norm were found. Only one of 4 cases had Centre for Organ Transplantation of Emilia Romagna a failure of hepatic coagulation factors. Hepatocytonecrosis and Region (CRT-ER), S. Orsola - Malpighi Hospital, cholestasis regressed after the spice withdrawal. Only in one case Bologna, Italy hepatitis lasted for 20 days. 7 Department of General Surgery and The etiopathogenesis of acute hepatitis associated with curcuma Transplantation, S. Orsola - Malpighi Hospital, intake has not yet been clarified; autoimmunity has also been sup- University of Bologna, Bologna, Italy posed. 8 Department of Medicine, Sports Medicine Unit We suggest to deep knowledge on the role of contaminants or DIMED, University of Padua, Padua, Italy any kind of agents used for cultivation, storage and transport, and 9 Department of Occupational Medicine, National to