th th SUMMER MEETING ONLINE – 17 & 18 June 2021

Speakers’ Details and Presentation Summaries The following details are in programme order. Use the PDF search button to quickly find a session or speaker.

OPEN SESSION – NATIONAL ASTHMA AND COPD AUDIT PROGRAMME Thursday 17th June: 08:00-09:00

Dr James Calvert qualified in Medicine from Oxford Session aims and overview University in 1992. He studied Public Health as a 1) To summarise the main findings of the 2020/21 Fulbright Scholar at Harvard University before NACAP reports. completing his PhD in Asthma Epidemiology in South 2) To outline the QI support opportunities offered by Africa and London. NACAP to clinical and audit teams. He was a Consultant Respiratory Specialist in Bristol from 2006-2021. He is now a Respiratory Consultant Professor Roberts will present a summary of key and Medical Director of Aneurin Bevan University reported findings from across the audits from the last Health Board in Wales. 12 months, highlighting areas for further James has worked with colleagues in the South West improvement. He will speak about the impact of and at NHS England to improve access to integrated COVID-19 on standards of care and on audit services for respiratory patients. He has Chaired the participation, along with plans to improve automated British Thoracic Society (BTS) Professional and extraction of NACAP data. Organisational Standards Committee and has been Dr Calvert will talk about the QI programme to be the BTS National Audit Lead. He has a longstanding launched this year. interest in quality improvement in health care and has A discussion will follow around ideas for improving worked with the BTS, NHS Improving Value, the Royal NACAP support to clinical and audit teams. College of Physicians (RCP) and the University of Bristol in this field. He was National Specialty Advisor for Severe Asthma from 2017-2020 and continues to lead the National Asthma Audit at the Royal College of Physicians.

Professor Mike Roberts is the Clinical Director of the National Asthma and COPD Audit Programme, for the Royal College of Physicians, and has led national audit in this field since 2001. He has held consultant posts with Barts Health, Princess Alexandra Hospital and Essex Partnership University Trust. He is Managing Director of UCL Partners Academic Health Science System and Deputy Director of the NIHR North Thames Applied Health Research Collaboration.

Speakers’ Details & Presentation Summaries th th SUMMER MEETING ONLINE – 17 & 18 June 2021

Speakers’ Details and Presentation Summaries The following details are in programme order. Use the PDF search button to quickly find a session or speaker.

SYMPOSIUM – YEAR IN REVIEW Thursday 17th June: 09:30-11:00

Dr Alanna Hare is a Consultant in Sleep and Pulmonary infection and COVID-19 Respiratory Failure at the Royal Brompton Hospital in This session will provide an overview of developments London. She graduated from Selwyn College, in respiratory infections over the previous 12 to 18 University of Cambridge in 1999, and completed her months, including those in COVID-19 and non- postgraduate training at Imperial College London in pandemic infections. 2002. She is Chair of the British Thoracic Society Education Dr Martin Allen is a Respiratory Physician at and Training Committee and Treasurer of the British University Hospital of North Staffordshire. Sleep Society. She sits on the Board of the Sleep He has interests in a variety of respiratory diseases Council. She was made Honorary Clinical Senior including COPD, ventilatory support / weaning and Lecturer at NHLI 2018. sleep medicine, originating from his research into sleep and physiological changes. Dr John Park is a Consultant at Oxford Universities He has fulfilled a variety of management and NHS Foundation Trust and is lead for Lung Cancer. He transformational roles within the hospital, including trained in the London and Oxford Deaneries. He CD and Medicine Divisional Head. completed a PhD in pulmonary vascular and structural He holds a variety of national roles including: sitting remodelling at Imperial College London, National on the British Thoracic Society Board, Chair of the Heart and Lung Institute. John is Honorary Treasurer Respiratory EWG on Coding, sits on the Respiratory of the BTS having previously been Chair of the BTS CRG, contributes to the Respiratory Long-Term Plan, Education and Training Committee. leading on pneumonia, works with the AHSN, is the GIRFT National Clinical Lead for Respiratory Medicine Dr David Connell a Consultant Physician in Respiratory and the NSA for physiological measurement. Medicine at NHS Tayside with clinical interests incorporating complex lung infections, particularly GIRFT – themes and outcomes: a review so far tuberculosis, chronic pulmonary aspergillosis, and The objectives of this presentation are to: non-tuberculous mycobacteria. He also works in - review the GIRFT methodology; medical high dependency and acute medicine, and - discuss methods of data extraction and data flow; has interests in the delivery of care in both chronic - highlight variations in care across English hospitals and acute respiratory infections, including influenza, and some of the reasons; and more recently COVID-19. He was the Clinical Lead - highlight recommendations to improve care, for Winter Planning during the pandemic winter of including COVID; 2020-21 at NHS Tayside, and is Chair of the Pulmonary - discuss opportunities for system working. Infection Specialist Advisory Group of the British Thoracic Society. During the first year of the pandemic, he was a co-opted member of the UK New and Emerging Respiratory Virus Threats Advisory Group (NERVTAG).

Speakers’ Details & Presentation Summaries th th SUMMER MEETING ONLINE – 17 & 18 June 2021

Speakers’ Details and Presentation Summaries The following details are in programme order. Use the PDF search button to quickly find a session or speaker.

SYMPOSIUM – MDT EXPERTISE: BEYOND THE DRUGS Thursday 17th June: 09:30-11:00 had on levels of physical activity in COPD patients will be Alison Armstrong, Nurse Consultant (Long Term Ventilation) made. Newcastle upon Tyne. Alison is the Nurse Consultant within the regional North-East Jennifer Murphy is a highly specialist Speech and Language Assisted Ventilation Service. Therapist for laryngeal disorders, based at Newcastle upon She represents nursing on a number of groups. She has a Tyne Hospitals. She is passionate about improving care for national role as Co-chair for the BTS Nurse Specialist Advisory patients with upper airway disorders, through supporting Group, as well as being an active member on their Education earlier identification, and developing interventions and and Training Committee. services to optimise patient care. She is an Honorary Alison is the host of the Specialists in Long-term Ventilation at Lecturer at Newcastle University and over the last three years Home (SiLVaH) National Network, which is a non-medical has been awarded three academic grants. This has enabled group for those working in the support of patients on home her to complete a Master’s in Public Health and Health Service mechanical ventilation. Research at Newcastle University, host several patient Alison has an MSc in Practice Development, and her main engagement research groups, and commence the early interest lies in assuring good quality of life for her complex development work of a complex intervention for inducible client group. laryngeal obstruction.

Dr Karen Heslop-Marshall is a Nurse Consultant working in The larynx: friend or foe? Newcastle upon Tyne. Karen’s main area of expertise is the This session will explore the role of the larynx, for voice, psychological impact of respiratory disease. Karen completed breathing and beyond. It aims to promote early identification a postgraduate diploma in cognitive behavioural therapy (CBT) of laryngeal disorders within the respiratory population; and in 2003 and developed a CBT treatment for patients with provide an insight into different treatment options. The respiratory problems who face psychological difficulties. Karen presentation will include an overview of laryngeal anatomy completed a National Institute of Health Research (NIHR) PhD and physiology, with examples of ‘normal’ and disordered Clinical Academic Training Research Fellowship from 2011 to laryngeal physiology and function. Videos of laryngeal 2016. Her PhD research was the largest RCT into CBT for COPD examinations will be shown to demonstrate how Speech and patients who experience anxiety and depression. Karen was a Language Therapists differentially diagnose laryngeal co-applicant of the NIHR TANDEM HTA Study using CBT and disorders, and showcase what impact laryngeal retraining pulmonary rehabilitation. exercises have upon the larynx.

Matthew Armstrong is a post-doctoral research fellow Rachael Moses is a Consultant Respiratory Physiotherapist working at the University of Northumbria Newcastle. He with an expert background in complex weaning, long term recently completed his PhD that investigated the feasibility, ventilation, airway clearance and advanced care planning. acceptability, and efficacy of a physical activity behavioural Rachael is fortunate to sit on a number of national modification intervention alongside pulmonary rehabilitation organisations, including the Chartered Society of and cognitive behavioural therapy in COPD patients with low Physiotherapy Council and Honorary Student President, NHSE baseline physical activity levels. Patient Safety Group, NCEPOD Study Advisor, Co-Chairs the Since completing his PhD, Matthew is the lead coordinator of National HMV-UK Committee, is a Placement Co-ordinator for several studies including the investigation of accessible Medical Aid for Palestinians and Multimedia Editor for Thorax community COVID-19 education and physical therapy for BMJ. She has most recently been appointed as President-Elect individuals with long COVID-19 as well as the delivery of virtual of the British Thoracic Society. physical activity promotion alongside core strength training in healthy middle-aged individuals. Long term non-invasive ventilation – evidence to practice: how hard can it be? Physical activity and how to improve it Long term ventilation is considered an essential life sustaining The aim of this presentation is to understand the complexity of intervention for people living with progressive long term physical activity in patients with COPD, investigating how and respiratory conditions requiring breathing support. There is why these patients become and remain physically inactive, and significant evidence for long term non-invasive ventilation in consider the methods required to improve it. Such methods some patient cohorts, such as those with neuromuscular including the addition of physical activity behavioural disease, but the evidence may be lacking in other patient modification strategies and cognitive behavioural therapy to groups. standard care pulmonary rehabilitation will be discussed. An This session will explore the current evidence among different acknowledgment to the impact that COVID-19 shielding has patient groups as well as translating this into clinical practice and will include patient experiences.

Speakers’ Details & Presentation Summaries th th SUMMER MEETING ONLINE – 17 & 18 June 2021

Speakers’ Details and Presentation Summaries The following details are in programme order. Use the PDF search button to quickly find a session or speaker.

SYMPOSIUM – PLEURAL MALIGNANCY: DIAGNOSIS AND MANAGEMENT – TIME FOR A RE-THINK Thursday 17th June: 09:30-11:00

Professor Najib M Rahman, Professor of Respiratory Kevin is an NHS Scotland Research (NRS) Senior Medicine, Lead for Pleural Diseases, Director, Oxford Research Fellow and leads a translational research Respiratory Trials Unit, University of Oxford and programme focused on pleural disease. He has a Oxford Centre for Respiratory Medicine, Churchill particular interest in mesothelioma and is Principal Hospital, Oxford, Deputy National CRN Lead for Investigator of the CRUK PREDICT-Meso International Respiratory Disease, NIHR CRN. Accelerator Network. Having qualified in Oxford, Najib underwent the medical SHO rotation at Queen’s Medical Centre, Modern cytological diagnosis of MPE – time to go Nottingham, and re-joined Oxford as a Specialist straight to thoracoscopy? Registrar in 2003. He undertook a DPhil and MSc in Pleural fluid cytology testing is embedded as a key this period and was appointed Director of the Oxford early step in the investigation of suspected pleural Respiratory Trials Unit and Consultant Lead for Pleural malignancy. This term covers a large number of Disease in Oxford in 2011. He was appointed as individual tests, which vary by intent (diagnostic, sub- Professor of Respiratory Medicine in 2018, and is typing, predictive marker), yield and clinical relevance. currently running randomised and observational This lecture will summarise recent data regarding the studies in pleural infection, pneumothorax and relative value of these tests in commonly encountered malignant pleural effusion. Najib is trained in clinical scenarios, including some in which a ‘direct to thoracoscopy, thoracic ultrasound and clinical trials biopsy’ approach is reasonable. methodology, and has published over 250 papers with citations of >6000. He is Co-chair of the BTS Pleural Dr Rahul Bhatnagar is a Consultant Respiratory Guidelines 2021, Chair of the BTS Pleural Intervention Physician at North Bristol NHS Trust and an Honorary Committee, and Chair of multiple ERS guidelines on Senior Lecturer at the University of Bristol Academic pleural disease. Respiratory Unit. He has a research interest in clinical trials in pleural disease, with an emphasis on Dr Eleanor Mishra is Pleural Lead at Norfolk and malignant effusions and their management, pleural Norwich University Hospital and Honorary Lecturer at infection, and thoracic ultrasound. He previously led the University of East Anglia. She is part of the British the IPC-Plus and TAPPS randomised trials, and was Thoracic Society committee revising the pleural named as a Royal College of Physicians disease guidelines. She is also on the Executive Quincentennial Lecturer in 2018. Committee of the UK Pleural Society, and in this role, organises the annual Pleural Research Day. For her Definitive MPE management: is in-patient DPhil, she led two practice changing trials for patients pleurodesis dead? with malignant pleural effusions. This talk will address recent studies relating to pleurodesis strategies, particularly those looking at Professor Kevin Blyth is Professor of Respiratory ambulatory approaches to malignant effusion Medicine at the University of Glasgow. He splits his management. Educational aims include: time between the CRUK Beatson Institute/University - understanding the historical place of inpatient of Glasgow and the Queen Elizabeth University pleurodesis; early studies of indwelling pleural Hospital, where he leads the Glasgow Pleural Disease catheters; and the rationale for outpatient MPE Unit. He founded and is Director of the Macmillan management; Scottish Mesothelioma Network, which coordinates - describing the evidence from recent randomised clinical care and access to trials for mesothelioma trials relating to IPCs and talc pleurodesis. patients in Scotland.

Speakers’ Details & Presentation Summaries th th SUMMER MEETING ONLINE – 17 & 18 June 2021

Speakers’ Details and Presentation Summaries The following details are in programme order. Use the PDF search button to quickly find a session or speaker.

SYMPOSIUM – SILICOSIS IN 2021: NEW CHALLENGES FROM AN “OLD” DISEASE Thursday 17th June: 11:30-13:00

Dr Chris Barber is a Respiratory Consultant with a Learning objectives; this talk will allow you to be: clinical and research interest in occupational lung 1) updated on the current UK evidence in relation to disease. His time is split between NHS clinical work in silicosis; Sheffield and HSE sessions at the Centre for 2) understand strategies to help identify patients Workplace Health in Buxton. early, including the use of health surveillance. He is a member of the Group of Occupational Respiratory Disease Specialists (GORDS), and the Dr Johanna Feary is a Senior Clinical Fellow at the current chair of the BTS Occupational and National Heart and Lung Institute, Imperial College Environmental Lung Disease Specialist Advisory and Honorary Respiratory Consultant at Royal Group. Brompton Hospital. She carried out a large epidemiological study of laboratory animal allergy as Dr Peter Reid trained in Belfast, London and part of an NIHR post-doctoral fellowship. Her clinical Edinburgh and was appointed to the Western General interests include the assessment and management of Hospital in 2000. He has an interest in occupational occupational lung disease, and difficult asthma. She is lung disease and is a member of GORDS. a member of GORDS (Group of Occupational Respiratory Disease Specialists) and, until recently, a Professor David Fishwick is a Consultant Respiratory member of the BTS SAG for Occupational and Physician in Sheffield and an Honorary Professor of Environmental Medicine. Occupational and Environmental Respiratory Medicine at the University of Sheffield. He also works Emerging health issues due to silica exposure as the Chief Medical Adviser for the Health and Safety This talk will be case-based and provide a broad Executive. He is a past chair, and current member of outline of the range of respiratory diseases caused by the BTS Occupational Lung Disease SAG. He is also Co- exposure to silica. The primary focus will be on the director of the Centre for Workplace Health and has emerging international problem of artificial stone active research interests in all aspects of occupational silicosis, other aggressive forms of silicosis and the lung diseases. association between silica exposure and connective tissue diseases. Early detection and case management Silicosis remains a disease of global importance. Often diagnosed late, there are no specific treatment approaches that are able to significantly alter the natural history. It is consequently key to identify this condition early, and consider workplace changes both for the affected individual and also for other potentially exposed workers. This talk will explore some of these issues globally, and summarise where we are at in the UK in terms of early identification of silicosis.

Speakers’ Details & Presentation Summaries th th SUMMER MEETING ONLINE – 17 & 18 June 2021

Speakers’ Details and Presentation Summaries The following details are in programme order. Use the PDF search button to quickly find a session or speaker.

SYMPOSIUM – CLINICAL GRAND ROUND Thursday 17th June: 11:30-13:00

CHAIRS & JUDGES

Dr Alanna Hare is a Consultant in Sleep and Professor Jon Bennett. From a non-medical Respiratory Failure at the Royal Brompton Hospital in background, Jon still has to pinch himself about how London. She graduated from Selwyn College, lucky he was to have found medicine, even in our University of Cambridge in 1999, and completed her strange COVID-19 and post COVID-19 world. He is postgraduate training at Imperial College London in grateful to have found respiratory medicine and to 2002. have had great support from the BTS and his She is Chair of the British Thoracic Society Education respiratory colleagues throughout his career. Jon has and Training Committee and Treasurer of the British been a consultant since 2000, firstly in Derby, and Sleep Society. She sits on the Board of the Sleep then from 2004 in the nationally renowned Glenfield Council. She was made Honorary Clinical Senior Hospital where he continues to age disgracefully. Lecturer at NHLI 2018. Jon is a COVID-19 survivor – swab negative – terrible self-technique, antibody positive. He can be seen Rachael Moses is a Consultant Respiratory doing his bit for the environment; cycle commuting Physiotherapist with an expert background in complex most days to and from Glenfield Hospital. As a native weaning, long term ventilation, airway clearance and Wulfrunian, he has the curse of supporting the mighty advanced care planning. Wolverhampton Wanderers. Rachael is fortunate to sit on a number of national Clinical interests include: lung cancer, interventional organisations, including the Chartered Society of respiratory procedures, medical education, general Physiotherapy Council and Honorary Student respiratory medicine. President, NHSE Patient Safety Group, NCEPOD Study Advisor, Co-Chairs the National HMV-UK Committee, Dr John Park is a Consultant at Oxford Universities is a Placement Co-ordinator for Medical Aid for NHS Foundation Trust and is lead for Lung Cancer. He Palestinians and Multimedia Editor for Thorax BMJ. trained in the London and Oxford Deaneries. He She has most recently been appointed as President- completed a PhD in pulmonary vascular and structural Elect of the British Thoracic Society. remodelling at Imperial College London, National Heart and Lung Institute. John is Honorary Treasurer Alison Armstrong, Nurse Consultant (Long Term of the BTS having previously been Chair of the BTS Ventilation) Newcastle upon Tyne. Education and Training Committee. Alison is the Nurse Consultant within the regional FINALISTS North-East Assisted Ventilation Service. She represents nursing on a number of groups. She 1) Cardiac failure and asymmetrical effusions. To tap has a national role as Co-chair for the BTS Nurse or not to tap? Specialist Advisory Group, as well as being an active Dr Michael Shiel, Morriston Hospital, Swansea member on their Education and Training Committee. Alison is the host of the Specialists in Long-term 2) Pompe and circumstance: the diagnostic challenge Ventilation at Home (SiLVaH) National Network, which of respiratory failure in patients post-COVID is a non-medical group for those working in the pneumonitis support of patients on home mechanical ventilation. Dr Lydia Guhaniyogi, University Hospital of Wales, Alison has an MSc in Practice Development, and her Cardiff main interest lies in assuring good quality of life for her complex client group. 3) A rare cause of tracheal ulceration Dr Joy Creaser-Thomas, Morriston Hospital, Swansea

Speakers’ Details & Presentation Summaries th th SUMMER MEETING ONLINE – 17 & 18 June 2021

Speakers’ Details and Presentation Summaries The following details are in programme order. Use the PDF search button to quickly find a session or speaker.

SYMPOSIUM – TB AND NON-TUBERCULOUS MYCOBACTERIUM: CHALLENGES TO TREATMENT Thursday 17th June: 11:30-13:00

Dr Shahideh Safavi is a Clinical Assistant Professor in disciplinary TB network. He contributes to outbreak Respiratory Medicine at University of Nottingham. Her response as part of the UK Emergency Medical Team. research interest is in the development of magnetic resonance imaging biomarkers of respiratory diseases. The challenge of latent TB She is currently doing a post-doc at University of This talk will: Nottingham funded by the Royal Society of Medicine. 1) review the biological and public health principles underpinning the concept of latent TB infection (LTBI); Dr Anna Rich. Having studied in Cambridge, almost all 2) summarise practical aspects and emerging research of her post-graduate medical training has been in developments in the diagnosis and management of Nottingham. She completed an RCP Fellowship with LTBI; an MD in lung cancer epidemiology in 2010, and took 3) briefly discuss complex unresolved questions, such up a consultant post in February 2011. As a as appropriate approaches to LTBI in the context of Respiratory Consultant, her time is split between lung drug-resistant TB. cancer and tuberculosis. Her interest in TB stems from a childhood in Nigeria, and work experience in Dr Martin Dedicoat is a Consultant Infectious Diseases Ethiopia and Malawi. Anna enjoys working within a Physician in Birmingham, UK. He also works part time multidisciplinary TB team, and the challenges, both as Consultant in Tuberculosis (TB) Prevention for the clinical and social, that come with this diverse patient UK Health Security Agency in the National TB Unit. group. Martin trained in London, Ecuador, Birmingham and South Africa. He is TB lead for Birmingham and Solihull Non-tuberculous mycobacterium: an overview of and a member of the BTS TB SAG, Joint TB Committee guidelines and MDRTB Advice Group. His main research interests Non-tuberculous mycobacteria (NTM) are a are in TB prevention and contact tracing. fascinating clinical entity and their prevalence is increasing. Anna’s aim is to provide an overview of the Global epidemiology of drug resistant TB available guidelines, both national and international, Drug resistant tuberculosis (TB) continues to be a and use clinical cases to explore their practical significant health problem worldwide. The number of implementation, relevance and limitations. diagnosed cases has risen over the past few years due to increasing access to diagnostics. The ongoing Dr Derek Sloan is an Infectious Diseases physician COVID-19 pandemic has affected TB control who works at the University of St Andrews and in NHS worldwide and has reversed many of the gains made Fife. His research interests include clinical trials of new over the past five years. This presentation will focus treatments for tuberculosis, collaborating with on the changes in drug resistant TB epidemiology and partners from the PanAfrican Consortium for the future measures being implemented to help move the Evaluation of Anti-tuberculosis Antibiotics (PanACEA) world towards the goal of TB eradication. and the Global TB Alliance. He has worked clinically on TB control in England and Scotland, and in several African countries (Kenya, South Africa, Malawi and Uganda). He contributes to the BTS MDR-TB Clinical Advisory Service and co-chairs Scotland’s multi-

Speakers’ Details & Presentation Summaries

th th SUMMER MEETING ONLINE – 17 & 18 June 2021

Speakers’ Details and Presentation Summaries The following details are in programme order. Use the PDF search button to quickly find a session or speaker.

OPEN SESSION – PATHWAYS TO RESEARCH FOR RESPIRATORY PROFESSIONALS Thursday 17th June: 13:30-14:15

Professor Anthony de Soyza is an Academic Dr Akhilesh Jha is a Clinical Lecturer in Experimental and Clinician/Physician-Researcher and an Honorary Consultant Respiratory Medicine at the University of Cambridge. His Physician at Newcastle upon Tyne Hospitals NHS research uses human challenge models to investigate Foundation Trust. He has undertaken UK Chief Investigator innate immunity to viral infection and its dysregulation in roles and recently started international lead investigator airway disease, for which he was awarded the Royal Society roles. This maps to his role as National Specialty lead for the of Medicine’s Young Respiratory Investigator Award. He is a NIHR National Respiratory Group working for the UK member of the BTS Science and Research Committee and a National Institute for Health Research Clinical Trials Junior Editor-in-Training for the American Journal of Network. He has recently taken on Chair of the NIHR Respiratory and Critical Care Medicine. He is keen to Health Technology Assessment in Hospital medicine develop a national network of respiratory early career prioritisation panel and welcomes discussion on the HTA! professionals for collaborative research projects.

Dr Alex Dipper is a South West based Respiratory Registrar Professor Najib M Rahman, Professor of Respiratory and Clinical Research Fellow at the Academic Respiratory Medicine, Lead for Pleural Diseases, Director, Oxford Unit, North Bristol NHS Trust. She is undertaking a PhD in Respiratory Trials Unit, University of Oxford and Oxford the management of malignant pleural effusions. She is co- Centre for Respiratory Medicine, Churchill Hospital, Oxford, chair of the PRISM Respiratory Trainee Research Network, Deputy National CRN Lead for Respiratory Disease, NIHR established in 2017 and the first respiratory collaborative CRN. trainee research network in the UK. Having qualified in Oxford, Najib underwent the medical SHO rotation at Queen’s Medical Centre, Nottingham, and Dr Karen Heslop-Marshall is a Nurse Consultant working in re-joined Oxford as a Specialist Registrar in 2003. He Newcastle upon Tyne. Karen’s main area of expertise is the undertook a DPhil and MSc in this period and was psychological impact of respiratory disease. Karen appointed Director of the Oxford Respiratory Trials Unit completed a postgraduate diploma in cognitive behavioural and Consultant Lead for Pleural Disease in Oxford in therapy (CBT) in 2003 and developed a CBT treatment for 2011. He was appointed as Professor of Respiratory patients with respiratory problems who face psychological Medicine in 2018, and is currently running randomised and difficulties. Karen completed a National Institute of Health observational studies in pleural infection, pneumothorax Research (NIHR) PhD Clinical Academic Training Research and malignant pleural effusion. Najib is trained in Fellowship from 2011 to 2016. Her PhD research was the thoracoscopy, thoracic ultrasound and clinical trials largest RCT into CBT for COPD patients who experience methodology, and has published over 250 papers with anxiety and depression. Karen was a co-applicant of the citations of >6000. He is Co-chair of the BTS Pleural NIHR TANDEM HTA Study using CBT and pulmonary Guidelines 2021, Chair of the BTS Pleural Intervention rehabilitation. Committee, and Chair of multiple ERS guidelines on pleural disease. He is Deputy Chair of the National Institute for Professor John Hurst is Professor of Respiratory Medicine Health Research CRN National Respiratory Group. at University College London, and Honorary Consultant Respiratory Physician at Royal Free London NHS Foundation Session overview Trust. He is National Lead for COPD with the Royal College Do you and your colleagues discuss topics for research that of Physicians National Asthma and COPD Audit would benefit your patients, but are unsure where to start? Programme. John is Editor in Chief of the European This open session is aimed at all members of the multi- Respiratory Monograph. He is currently a member of BTS professional team. You will hear from early career Council. His clinical and research interests centre on investigators who are working on research and quality exacerbations of COPD. He is Deputy Chair of the National improvement projects. Hear how they got started, how Institute for Health Research CRN National Respiratory research questions are set, and the wider benefits of Group. collaboration.

Speakers’ Details & Presentation Summaries

th th SUMMER MEETING ONLINE – 17 & 18 June 2021

Speakers’ Details and Presentation Summaries The following details are in programme order. Use the PDF search button to quickly find a session or speaker.

MINI SHORT COURSE – OXYGEN (PART 1): IN THE HOSPITAL Thursday 17th June: 14:30-16:00

Alison Armstrong, Nurse Consultant (Long Term Emergency oxygen therapy Ventilation) Newcastle upon Tyne. The BTS Oxygen Guidelines recommend target oxygen Alison is the Nurse Consultant within the regional saturations 88-92% in most patients hospitalised with North-East Assisted Ventilation Service. She COPD exacerbation, and their introduction was represents nursing on a number of groups. She has a temporally associated with a sustained drop in national role as Co-chair for the BTS Nurse Specialist hospital mortality rates. In patients managed with Advisory Group, as well as being an active member on oxygen, admission oxygen saturations above 88-92% their Education and Training Committee. are associated with higher risk-adjusted in-hospital Alison is the host of the Specialists in Long-term mortality, including in those with normocapnia. Ventilation at Home (SiLVaH) National Network, which Patients with bronchiectasis, morbid obesity, is a non-medical group for those working in the neuromuscular disease and chest wall deformity share support of patients on home mechanical ventilation. similar risks and thus the same target oxygen Alison has an MSc in Practice Development, and her saturation range. Across a wide range of other main interest lies in assuring good quality of life for conditions, the IOTA meta-analysis showed that her complex client group. compared to liberal oxygen therapy, conservative oxygen target saturations were associated with better Dr Rachel Dancer is a Consultant in Acute Medicine at survival, but more recent RCTs in acute coronary Warwick Hospital. She previously completed her syndrome and critical illness have not confirmed harm training in Respiratory Medicine in Birmingham. She from liberal oxygen therapy. It is most important that has many interests, including acute respiratory oxygen is prescribed and administered within a target medicine and smoking cessation. range, appropriately monitored to avoid hypoxia and hyperoxia. Professor Stephen Bourke is the Clinical Lead for COPD and NIV in Northumbria Healthcare NHS Foundation Trust and Honorary Professor of Respiratory Medicine, Newcastle University. He leads a COPD research programme which includes the development of prognostic scores to risk stratify patients with severe exacerbations of COPD for mortality (DECAF) and readmission (PEARL), an RCT of hospital at home selected by low-risk DECAF score and a 10-centre NIV Outcomes study.

Speakers’ Details & Presentation Summaries

th th SUMMER MEETING ONLINE – 17 & 18 June 2021

Speakers’ Details and Presentation Summaries The following details are in programme order. Use the PDF search button to quickly find a session or speaker.

JOINT BTS/BSTI SYMPOSIUM – THORACIC ULTRASOUND: THE NOW AND THE NEW Thursday 17th June: 14:30-16:00

Ema Swingwood is currently an NIHR Clinical hospitals. From 1991 to 1992, he spent time Academic Research Fellow at the University of the at Vancouver General Hospital, Canada, as part of a West of England thoracic imaging fellowship. (UWE). Her substantive post is as the Respiratory Professor Padley is a cardiac and thoracic radiologist, Pathway Lead Physiotherapist at University Hospitals specialising in thoracic and vascular imaging and Bristol and Weston NHS Foundation Trust. Her area of intervention, and general body imaging. clinical expertise and interest is ventilation, weaning He leads the interventional radiology service and co- and complex airway clearance. leads lung cancer and cardiac CT services. In his role at Having completed the Advanced Cardiorespiratory Chelsea & Westminster Hospital, he provides general, Physiotherapy MSc programme at University College thoracic and interventional radiology. London (UCL) in 2012, Ema has continued her He provides interventional radiology services related research focusing on the use of Mechanical to lung cancer and vascular intervention. Insufflation-Exsufflation (MI-E) and other cough Professor Padley's current research interests include: augmentation strategies. Her current PhD work percutaneous ablation of lung tumours; dose focuses on the use of MI-E in the intubated optimisation in CT; novel imaging techniques in population. paediatric lung disease; and MRI of the large and Extra-curricular activities include contributions to the small airways. Undergraduate Physiotherapy programme at UW, and post-graduate teachings at University College London. Simon Hayward is a Specialist Practice Development She sits on the BTS Education and Training Physiotherapist in Lung Ultrasound at Blackpool Committee, PHE Independent High-Risk Aerosol Teaching Hospitals NHS Foundation Trust. Generating Procedures Panel, ICS WARE project as the Most of Simon’s experience has been in acute NHS AHP representative and is the ongoing Chair of the respiratory services and he has been using lung Association of Chartered Physiotherapists in ultrasound (LUS) to inform his clinical practice since Respiratory Care. 2013. In 2016 he initiated an LUS training programme aimed primarily at physiotherapists. To date >200 Professor Simon Padley has been a Consultant physiotherapists have attended his “Introduction to Radiologist at Royal Brompton, Harefield and Chelsea Lung Ultrasound” courses which are run around the and Westminster hospitals since 1994 and is also an UK and Europe. Honorary Consultant at The Royal Marsden Hospital. In 2017 Simon became a member of the Intensive In 2015, Professor Padley became Director of Care Society’s (ICS) Focused Ultrasound Intensive Care Radiology at the Royal Brompton and Harefield NHS (FUSIC) Committee as the Allied Health Professions Foundation Trust. He is also Professor of Practice in (AHP) representative. He also runs the Physiotherapy Diagnostic and Interventional Radiology at Imperial Lung Ultrasound (+PLUS) Specialist Interest Group. College London, in the Lung Division for the National Heart and Lung Institute. TUS: a physiotherapist’s perspective He studied physiology at King's College London, and Simon will discuss the evolution of TUS as a tool for medicine at Westminster Hospital Medical School respiratory physiotherapists and where the profession (now part of Imperial College London), graduating in currently stands with its adoption of TUS into practice. 1984. He completed further training in radiology at Simon will also share the experiences of 20 TUS Addenbrooke's, Papworth, and Westminster accredited respiratory physiotherapists following

Speakers’ Details & Presentation Summaries

th th SUMMER MEETING ONLINE – 17 & 18 June 2021

Speakers’ Details and Presentation Summaries The following details are in programme order. Use the PDF search button to quickly find a session or speaker.

receipt of their answers to the question: “What is the Disease in Oxford in 2011. He was appointed as single most important aspect of your practice that TUS Professor of Respiratory Medicine in 2018, and is allows you to do now, that you couldn’t do before currently running randomised and observational gaining your accreditation?” To conclude, Simon will studies in pleural infection, pneumothorax and highlight upcoming work and potential areas for malignant pleural effusion. Najib is trained in development. thoracoscopy, thoracic ultrasound and clinical trials methodology, and has published over 250 papers with Professor Najib M Rahman, Professor of Respiratory citations of >6000. He is Co-chair of the BTS Pleural Medicine, Lead for Pleural Diseases, Director, Oxford Guidelines 2021, Chair of the BTS Pleural Intervention Respiratory Trials Unit, University of Oxford and Committee, and Chair of multiple ERS guidelines on Oxford Centre for Respiratory Medicine, Churchill pleural disease. Hospital, Oxford Deputy National CRN Lead for Respiratory Disease, TUS: a physician’s perspective NIHR CRN. This talk will discuss the basics of training in thoracic Having qualified in Oxford, Najib underwent the ultrasound according to the new BTS guidelines, and medical SHO rotation at Queen’s Medical Centre, then discuss the clinical utility of thoracic ultrasound Nottingham, and re-joined Oxford as a Specialist in current practice. Potential future directions for Registrar in 2003. He undertook a DPhil and MSc in ultrasound use by the physician will be covered on the this period and was appointed Director of the Oxford basis of new and recently published data. Respiratory Trials Unit and Consultant Lead for Pleural

Speakers’ Details & Presentation Summaries

th th SUMMER MEETING ONLINE – 17 & 18 June 2021

Speakers’ Details and Presentation Summaries The following details are in programme order. Use the PDF search button to quickly find a session or speaker.

SYMPOSIUM – ASTHMA: AN MDT APPROACH Thursday 17th June: 14:30-16:00

Dr Matthew Martin is an NIHR Clinical Lecturer at the patients for biologic therapies. He also provides care to Nottingham Respiratory Biomedical Research Centre and patients with other respiratory conditions including: cystic Respiratory Registrar at Nottingham University Hospitals fibrosis, COPD and interstitial lung disease. NHS Trust. He completed a PhD on the phenotyping of asthma and cough at the University of Nottingham in 2017. Professor Adel Mansur is Consultant Physician and His research interests include phenotyping of asthma and Honorary Professor, University Hospitals Birmingham and investigating the underlying mechanisms and patient University of Birmingham, UK. experience of asthma attacks. Adel graduated from Tripoli/Libya Medical College and undertook postgraduate medical training in Glasgow and Dr Runa Ali is a Consultant Physician in Respiratory Dudley and higher medical and respiratory training in Leeds Medicine and Allergy at Barts Health. She is Co-chair of the and West Midlands. He was awarded a doctorate in asthma North Central and East London Severe Asthma Network and genetics by the University of Leeds in 1998 and has been Trust Clinical Lead for Allergy. She led the Severe Asthma Consultant Physician at Birmingham Heartlands Hospital Service from 2013-2016. since 2002 and was recently awarded an Honorary Chair in Runa trained in London and undertook a PhD at the Respiratory Medicine by the University of Birmingham. He National Heart and Lung Institute, Royal Brompton holds special interest in severe and difficult to treat asthma Hospital. She is an Honorary Clinical Senior Lecturer, Queen and has been the lead for the Birmingham Regional Severe Mary College University of London and has been principal Asthma Service which covers the West Midlands and investigator in multi-centre trials. beyond since 2002. He has developed a multidisciplinary Runa has acted for Her Majesty’s Coroner as Expert approach to management of difficult to treat asthma and Witness. She is an Allergy UK Health Advisory Board an active research programme composed of strands member, and was on the Executive Council of the British ranging from asthma genetics, biomarkers in asthma, Society for Allergy and Clinical Immunology (BSACI) and the diagnostics, adherence, phenotyping, asthma therapeutics Joint Committee for Immunology and Allergy at the Royal including biologics, psychosomatic disorders, upper airway College of Physicians. dysfunction and allied co-morbidities. He has authored approximately 100 peer review articles. Dr Helen Hope, Principal Clinical Psychologist. Helen currently leads the psychology service within the Professor Andrew Menzies-Gow is the Director of the Lung Manchester Severe Asthma and Airways Service for Division at the Royal Brompton Hospital and a Professor of individuals living with severe asthma, inducible laryngeal Practice (Respiratory Medicine) at Imperial College where obstruction, tracheomalacia and/or breathing pattern his research interests include novel therapies for severe disorders. She has worked in respiratory medicine, asthma and eosinophilic lung disease. He is the National specifically severe asthma, since October 2014. In addition, Clinical Director for Respiratory Disease for NHS England she has worked in additional respiratory services including and Improvement and Chair of the Adult Specialised lung transplant and long-term ventilation. Within the last Respiratory Clinical Reference Group for NHS England 12 months, Helen has co-developed and co-led an interim Specialised Commissioning. inpatient-based psychology service for individuals admitted with COVID-19 and also contributed to the long-COVID Claire Slinger, Consultant Speech and Language Therapist, pathway design and development. Professional Advisor to Royal College of Speech and Language Therapists (Field of Adult Respiratory care). Douglas Johnson has worked as a pharmacist in secondary Claire’s areas of interest include inducible laryngeal care for almost seven years having graduated from the obstruction (ILO) and chronic cough management. She is University of Nottingham in 2013 and qualifying as a currently working as Consultant SLT and Service Lead for pharmacist in 2014. Currently, he works as a Specialist Preston Complex Breathlessness (Airways) Multi- Clinical Pharmacist in Respiratory Medicine at Nottingham Disciplinary Team, Lancashire Chest Centre, Royal Preston University Hospitals NHS Trust. As part of his role, he is a Hospital, Lancashire Teaching Hospitals Trust. member of the Nottingham Severe Asthma Service Multidisciplinary Team which meets monthly to assess

Speakers’ Details & Presentation Summaries

th th SUMMER MEETING ONLINE – 17 & 18 June 2021

Speakers’ Details and Presentation Summaries The following details are in programme order. Use the PDF search button to quickly find a session or speaker.

MINI SHORT COURSE – OXYGEN (PART 2): OUT OF HOSPITAL Thursday 17th June: 16:30-18:00 other than COPD may respond differently to altitude- Alison Armstrong, Nurse Consultant (Long Term related hypoxaemia. Finally, there is much greater Ventilation) Newcastle upon Tyne. availability of portable oxygen concentrators (POCs). A Alison is the Nurse Consultant within the regional North- wide variety of such devices now provide differing flow East Assisted Ventilation Service. She represents nursing rates and modes of delivery, and not all are suitable for on a number of groups. She has a national role as Co- all individual patients. chair for the BTS Nurse Specialist Advisory Group, as well as being an active member on their Education and Dr Carlos Echevarria is a respiratory physician with an Training Committee. interest in COPD and CF. He completed his PhD in COPD Alison is the host of the Specialists in Long-term exacerbation, focussing on risk prediction and hospital at Ventilation at Home (SiLVaH) National Network, which is home services; he has recently studied the association of a non-medical group for those working in the support of oxygen saturations at admission and inpatient death in patients on home mechanical ventilation. this group. Alison has an MSc in Practice Development, and her main interest lies in assuring good quality of life for her Smoking and oxygen complex client group. This presentation will look at the indications and contraindications of long-term oxygen therapy in Dr Rachel Dancer is a Consultant in Acute Medicine at patients with COPD. It will consider the clinical benefits Warwick Hospital. She previously completed her training and potential hazards of using long-term oxygen therapy in Respiratory Medicine in Birmingham. She has many in patients who smoke and also consider the ethical interests, including acute respiratory medicine and implications of this approach. smoking cessation. Vicky Campbell is Respiratory Consultant Nurse clinically Dr Robina Coker is Consultant and Honorary Senior leading a community multi-disciplinary specialist Lecturer in Respiratory Medicine at Hammersmith respiratory team in Stoke on Trent and Hospital and Imperial College London, and Clinical Staffordshire. She has a career of 27 years working Director of NWL NIHR Clinical Research Network. equally in acute hospital care and community. Vicky is an Robina established the BTS Air Travel Working Party in HOS-AR lead and actively assesses patients for 2000, and chaired it until 2011. In 2018 she was oxygen, supporting patients living with respiratory appointed Chair of the new BTS Air Travel Committee. In disease plus other long-term conditions. She is a November 2019 Robina was awarded the 2019 Bronze member of the West Midlands Home Oxygen Group and Medal from the Royal Aeronautical Society, in Staffordshire's Respiratory Clinical Network. She recognition of her achievements in developing provides educational support recommendations to improve safety for passengers with across community and primary care settings and for lung disease undertaking commercial air travel. local universities. Publication of the BTS Clinical Statement, ‘Air Travel and Respiratory Disease’, is expected in 2020. Ambulatory oxygen The purpose of this session is to reflect on the guidance Oxygen and air travel for ambulatory oxygen therapy (AOT) assessment and This presentation will highlight the challenges of use as recommended in the BTS Home Oxygen commercial air travel for passengers with respiratory Guidelines and Quality Standards for Home Oxygen use disease, with particular reference to the risk of in Adults. Through this there will be the practical hypoxaemia. considerations of assessing patients during the It will emphasise developments in three areas over the pandemic coupled with the need for a compassionate last decade. The first is the attempt to define more assessment of a person's needs and the challenges this precisely the role of the hypoxic challenge test. The presents for Home Oxygen Services. This presentation second is increasing recognition that patient groups will also briefly consider the person’s ambulatory oxygen needs inside and outside the home.

Speakers’ Details & Presentation Summaries

th th SUMMER MEETING ONLINE – 17 & 18 June 2021

Speakers’ Details and Presentation Summaries The following details are in programme order. Use the PDF search button to quickly find a session or speaker.

SYMPOSIUM – PULMONARY REHABILITATION: A 2021 VISION Thursday 17th June: 16:30-18:00 investigating different rehabilitation strategies for Professor Ioannis Vogiatzis, Professor of Rehabilitation patients with chronic respiratory disease. Sciences, Department of Sport, Exercise and Rehabilitation, Faculty of Health and Life Sciences Comprehensive pulmonary rehabilitation beyond COPD Lead, Multidisciplinary Research Theme (MDRT) The content of this presentation will include an overview on Integrated Health and Social Care. of the evidence-base for pulmonary rehabilitation in Ioannis is an internationally recognised scientist in the chronic respiratory diseases including but not limited to area of pulmonary rehabilitation in respiratory disease. bronchiectasis, interstitial lung disease and asthma. He contributes his expertise to educational and research Where possible, the adaptation of exercise prescription curriculum development activities undertaken by the or content of the education programme for different European Respiratory Society (ERS). He has co-authored diseases will be addressed. Workforce skills, programme six Official Position Statements on clinical exercise and structure and national issues including capacity will also pulmonary rehabilitation in respiratory patients, which be discussed. have been published by the American Thoracic and Educational aims: European Respiratory Societies. He is Secretary of the 1) to understand the evidence-base for pulmonary Respiratory, Clinical Care and Physiology Assembly of the rehabilitation for select chronic respiratory diseases ERS, a member for the COPD Development Group of the (bronchiectasis, interstitial lung disease, asthma); World Health Organisation (WHO) Rehabilitation 2) to understand what is required at service and national Programme, and member of the Specialist Advisory level to deliver comprehensive pulmonary rehabilitation Group for Pulmonary Rehabilitation of the British for non-COPD chronic respiratory diseases. Thoracic Society. Dr Rachael Evans is an Associate Professor at the Dr Theresa Harvey-Dunstan, Assistant Professor of University of Leicester and Honorary Consultant Physiotherapy and Academic Plan Lead for UG Respiratory Physician at Glenfield Hospital, Leicester, UK. Physiotherapy, Physiotherapy and Rehabilitation Her doctorate investigated combined exercise Sciences, School of Health Sciences, Queen’s Medical rehabilitation for patients with COPD and heart failure. Centre Nottingham. She continued research into exercise and chronic disease Theresa has a teaching and research interest in during both her post-doctoral fellowship in Toronto, respiratory rehabilitation, exercise outcomes and Canada and her NIHR clinical lectureship in Leicester. She measures of frailty. She has a clinical background in the currently holds an NIHR Clinician Scientist Fellowship. acute and chronic management of people with medical She is the European Respiratory Society Pulmonary respiratory conditions and has a particular interest in Rehabilitation (PR) Group Secretary, a member of the COPD. Her PhD explored the repeatability and American Thoracic Society PR Assembly Programme responsiveness of exercise outcomes to pulmonary Committee and a member of the BTS PR Guideline rehabilitation (PR), bronchodilation or usual care. As a Committee. physiotherapist, she is keen to understand and develop physiotherapeutic strategies for respiratory illness, Cardiac and pulmonary rehab – same same but including the rehabilitation of long term and complex different conditions and co-morbidities. She is Co-chair of the BTS Cardiac rehabilitation and pulmonary rehabilitation are PR Specialist Advisory Group. two internationally established services and are typically delivered by a different workforce. The aims of the Dr Claire Nolan is a Senior Research Physiotherapist at services, the target populations, and outcomes will be Harefield Respiratory Research Unit. She is also the Co- discussed. As the prevalence of multi-morbidity chair of the BTS Pulmonary Rehabilitation Specialist increases, perhaps new models of care are required? Advisory Group. Her research interests are pulmonary This talk will cover the potential benefits and challenges rehabilitation, functional performance and physical of combining services to provide comprehensive care for activity and she is currently working on projects a wider group of patients.

Speakers’ Details & Presentation Summaries

th th SUMMER MEETING ONLINE – 17 & 18 June 2021

Speakers’ Details and Presentation Summaries The following details are in programme order. Use the PDF search button to quickly find a session or speaker.

SYMPOSIUM – CRITICAL CARE AND BEYOND Thursday 17th June: 16:30-18:00

Professor Sanjay Agrawal is a Consultant in from the Faculty of Intensive Care Medicine, the Respiratory and Intensive Care Medicine at the Intensive Care Society and the British Thoracic Society University Hospitals of Leicester NHS Trust (UHL), and produced a set of evidence-based guidelines, based has worked in critical care units for over 25 years. on the GRADE system, on the treatment of ARDS. Intensive care short- and long-term outcomes have This presentation will summarise the always been an important consideration and even recommendations in these guidelines with updates on more so now with the COVID-19 pandemic. new evidence, including recent studies in patients with COVID-19. Professor Andrew Bentley is a Consultant in Intensive Care and Respiratory Medicine at Wythenshawe Dr Caroline Sampson is Consultant in Anaesthesia, Hospital, Manchester University NHS Foundation Critical Care and Adult ECMO. Trust. He is an Honorary Professor at the University of Caroline trained in anaesthesia and critical care in Manchester and clinical lead for the Long-Term London and the Midlands, and has been a Consultant Ventilation Service with a particular interest in at Glenfield Hospital since 2014. Alongside general, weaning from prolonged mechanical ventilation. He cardiac and ECMO intensive care duties, she retrieves has spent many years in hospital management roles patients with severe acute respiratory failure both and supporting national advisory groups in critical conventionally and using mobile ECMO. Her specialist care and home ventilation. Andrew has worked with interests lie in SARF and adult ECMO alongside the Intensive Care Society for two terms and chaired medical education and critical care follow-up. Caroline the Society’s Research Foundation. More recently he is currently the Deputy Director for Adult ECMO at champions critical care research as Great Manchester Glenfield Hospital and runs the ECMO fellowship CRN Specialty Lead for Critical Care. programme and follow up clinics.

Dr Simon Baudouin is Consultant in Respiratory Respiratory critical care outcomes Medicine and Home Ventilation at the Royal Victoria This presentation will cover: Infirmary, Newcastle upon Tyne. He is a Trust Board 1) defining critical care outcomes; Member of the Intensive Care National Audit and 2) the ugly truth of (prolonged) critical care; Research Centre (ICNARC) and a member of the 3) the optimist respiratory specialist vs the pessimistic British Thoracic Society Standards of Care Committee. intensivist: He has been a Board member of the Faculty of a) COPD Intensive Care Medicine and a Council member of the b) Pulmonary fibrosis Intensive Care Society. c) Muscular dystrophy His research interests include rehabilitation following d) Outcomes in COVID-19 critical illness, sepsis and peri-operative care. Learning objectives are: 1) to improve understanding of the limits of critical ARDS: what works and what doesn’t? An update on care; current treatment recommendations 2) to understand the complexity of decision making The Acute Respiratory Distress Syndrome is a common for ICU admission and escalation in respiratory problem in the critically ill causing severe hypoxaemic patients; respiratory failure. The COVID-19 pandemic has 3) to understand the likely benefits versus risks of resulted in large numbers of patients with ARDS being critical care when planning future care for certain admitted to critical care units throughout the world. chronic respiratory conditions; Before the COVID-19 pandemic a joint working group 4) To understand the outcomes of severe COVID-19 requiring critical care.

Speakers’ Details & Presentation Summaries

th th SUMMER MEETING ONLINE – 17 & 18 June 2021

Speakers’ Details and Presentation Summaries The following details are in programme order. Use the PDF search button to quickly find a session or speaker.

SYMPOSIUM – COPD: WHEN TRIPLE THERAPY FAILS Friday 18th June: 08:30-10:00

Professor John Hurst is Professor of Respiratory Mona leads a group with research interests in the Medicine at University College London, and Honorary field of airways disease, particularly the investigation Consultant Respiratory Physician at Royal Free London of the mechanisms underlying exacerbations of COPD. NHS Foundation Trust. He is National Lead for COPD This has led to studying the role of the eosinophil in with the Royal College of Physicians National Asthma COPD, using statistical approaches to define particular and COPD Audit Programme. John is Editor in Chief of sub-groups and to the delivery of therapeutic the European Respiratory Monograph. He is currently strategies to patients, working across the translational a member of BTS Council. His clinical and research spectrum. interests centre on exacerbations of COPD. Azithromycin, Roflulimast, biologics Professor Alice Turner graduated from the University The aim of this talk is to review the evidence in COPD of Leicester and has done postgraduate training via for treatment beyond inhaled therapy. It will include a the Universities of Dundee and Birmingham, the latter review of the likely action of mechanism of these being where she completed a PhD focussed on COPD drugs (Azithromycin, Roflulimast and monoclonal and alpha 1 antitrypsin deficiency (AATD). She has antibodies), review of the data so far, and when and been a Consultant in Respiratory Medicine at which patient to consider using in. Heartlands Hospital since 2011, and is a Reader in Respiratory Medicine at the University of Birmingham. Professor Pallav Shah is currently Professor of In addition, Alice has been a member of the BTS Medicine at Imperial College, London, He is a Specialist Advisory Group on COPD and the European Consultant Physician at the Royal Brompton Hospital, Respiratory Society Task Force on AATD. She has and Chelsea and Westminster Hospital. He qualified in published widely in COPD and AATD, and has ongoing medicine at Guy’s Hospital Medical School, London research projects funded by the Alpha 1 Foundation, and trained in thoracic medicine at the Royal NIHR, ATS Foundation and others. Brompton Hospital. He is also Fellow of the European Respiratory Society. Professor Mona Bafadhel completed medical training Pallav is active in both the research and the at the University of Birmingham, followed by training development of new treatments. He has pioneered at Birmingham Heartlands Hospital and The Royal numerous bronchoscopic therapies for emphysema, Brompton Hospital. Mona is a clinical researcher, COPD, asthma and lung cancer. He has over 200 working in the Nuffield Department of Medicine as an papers and several books, including his contribution Associate Professor in Respiratory Medicine at the as sectional editor of the thoracic section of Grays University of Oxford and an Honorary Respiratory Anatomy (39th & 40th editions) and as sectional editor Consultant Physician at the Oxford University for respiratory section of the Oxford Textbook of Hospitals NHS Foundation Trust. Her interests in Medicine (6th edition). He is also the author of an Atlas respiratory medicine led to specialist training in the of Flexible Bronchoscopy and chief editor of Essentials Oxford deanery and subsequently gaining a PhD at the of Clinical Pulmonology. University of Leicester studying biomarkers in exacerbations of chronic obstructive pulmonary Lung volume reduction: surgery, valves and emerging disease (COPD). techniques In 2019, Mona was awarded the prestigious Lung volume reduction is established as an effective Gaulstonian Lectureship from the Royal College of treatment strategy in patients with COPD and Physicians, London. She is the 4th woman in the evidence of hyperinflation. The two main techniques awards 350-year-old history to have received this for are unilateral/single sequential VATS lung volume Excellence in the Clinical Sciences. reduction surgery and endobronchial valves. Emerging

Speakers’ Details & Presentation Summaries

th th SUMMER MEETING ONLINE – 17 & 18 June 2021

Speakers’ Details and Presentation Summaries The following details are in programme order. Use the PDF search button to quickly find a session or speaker.

techniques include endobronchial coils, vapor or Transplantation in COPD: who, when and how do thermal ablation and the use of sealants or biological they do? glues. Chronic obstructive pulmonary disease (COPD) is one Bronchoscopic techniques are also evolving to treat of the leading indications for lung transplantation, other COPD subtypes with vagal nerve denervation however, identifying those COPD patients who are and the use of liquid nitrogen cryospray for chronic likely to benefit from transplantation can be a bronchitis. challenge. In this session we will highlight the patients Learning outcomes: most likely to benefit from lung transplant, discuss the 1) the optimal selection of patients and anatomical ideal timing and type of transplant, and demystify the targets for BLVR; criteria for transplant referral and listing. The session 2) when to consider vapor therapy/endobronchial will also consider how best to optimise potential coils/sealants; transplant candidates and the positive impact 3) patient selection for denervation; transplant can have on survival and quality of life in 4) patient selection for cryospray. this population.

Dr Caroline Patterson completed her undergraduate training at the University of Nottingham. During a 16- year career as an RAF Medical Officer she achieved the rank of Wing Commander and completed higher medical training on the North West Thames Rotation. She was awarded an MD from Imperial College, London and on completion of clinical training she spent nine months at Duke University, USA, as the International Society for Heart and Lung Transplantation (ISHLT) Travelling Fellow in Lung Transplantation. She remains active in ISHLT as a Journal Watch editor and contributing author for various ISHLT consensus statements. Caroline was appointed as a Consultant Respiratory and Lung Transplant Physician at Royal Papworth Hospital in 2016.

Speakers’ Details & Presentation Summaries

th th SUMMER MEETING ONLINE – 17 & 18 June 2021

Speakers’ Details and Presentation Summaries The following details are in programme order. Use the PDF search button to quickly find a session or speaker.

SYMPOSIUM – FUTURE DIRECTIONS IN INTERSTITIAL LUNG DISEASE Friday 18th June: 08:30-10:00

Dr Nazia Chaudhuri is a Respiratory Physician and the Dr Katherine Myall is a Respiratory Registrar currently Clinical Lead for the Interstitial Lung Disease (ILD) working as a Research Fellow in Interstitial Lung service at the Manchester University NHS Foundation Disease at Guy’s and St Thomas’s NHS Foundation Trust (MFT), UK. She is an Honorary Senior Lecturer at Trust. She is completing an MD entitled Fibrotic the University of Manchester. She is also Deputy Interstitial Lung Disease and Nocturnal Oxygenation. Clinical Director of the Respiratory Directorate at MFT. Sleep and ILD Professor Michael Gibbons is a Consultant We will review the existing evidence regarding sleep Respiratory Physician at the Royal Devon and Exeter physiology in patients with fibrotic interstitial lung Foundation NHS Trust and Honorary Associate disease as well as its effect on quality of life and Professor at the University of Exeter. He is Clinical prognosis. We will go on to explore the potential Director of the South West Peninsula ILD Network and mechanisms which link sleep and disease for these Clinical Director of the NIHR Local Clinical Research patients. Network: South West Peninsula. He is a past Chair of the BTS Specialist Advisory Group for ILD, a previous Dr Theresia Mikolasch is a Respiratory Consultant at member of the BTS ILD Registry Steering Committee Cambridge University Hospitals. She qualified from and has been a member of the BTS Science and Edinburgh University and trained in respiratory Research Committee, BTS Council and BTS medicine in the East of England. She undertook her Professional Organisational and Standards of Care PhD at UCL with a focus on diagnosis and Committee. prognostication in idiopathic interstitial pneumonias.

Professor Gisli Jenkins is a respiratory physician and Progressive fibrosis in ILD cell and molecular biologist studying how the lung This talk will try to answer the following questions: responds to injury to understand what drives 1) What markers of progression are known for IPF and progressive pulmonary fibrosis rather than healing, other fibrosing ILDs? repair and regeneration. He is an NIHR Research 2) Can we predict who will progress at the outset? Professor, he leads the Margaret Turner Warwick 3) What is the treatment effect in IPF? Centre for Fibrosing Lung Diseases at the National 4) What evidence is there for treating non-IPF Heart and Lung Institute and is an Honorary progressive fibrosing ILDs? Consultant Physician at the Royal Brompton Hospital, 5) What do the guidelines say and how might they London. change in the near future?

ILD and COVID-19 1) Overview of COVID-19 and it potential to cause pulmonary fibrosis. 2) Evidence that COVID-19 might lead to pulmonary fibrosis. 3) Strategies to prevent the development of post COVID-19 fibrosis.

Speakers’ Details & Presentation Summaries

th th SUMMER MEETING ONLINE – 17 & 18 June 2021

Speakers’ Details and Presentation Summaries The following details are in programme order. Use the PDF search button to quickly find a session or speaker.

SYMPOSIUM – RESPIRATORY DISEASE: IT’S NOT JUST THE LUNGS Friday 18th June: 08:30-10:00

Dr Lola Loewenthal is currently undertaking a PhD development of cardiovascular disease, through chronic phenotyping severe asthma at Imperial College London tissue hypoxia, oxidative stress and chronic and the Royal Brompton Hospital. She is a respiratory inflammation: and in some circumstances the registrar in South London and is Chair of the BTS treatments themselves have detrimental cardiovascular Specialty Trainees Advisory Group (STAG). She has effects. In this talk, Paul aims to provide an overview of completed a National Medical Director Clinical common cardiovascular complications: coronary artery Fellowship at the Faculty of Medical Leadership and disease, arrhythmias and heart failure; and their Management (FMLM) and a Master’s in Clinical relationship with chronic lung disorders. He will also Education. discuss potential treatment strategies that may mitigate against these important comorbidities. Dr Sheila Ramjug is a Respiratory Consultant at Wythenshawe Hospital, Manchester Foundation Dr Clare Sander is a Consultant Respiratory Physician at Trust and has a specialist interest in pulmonary vascular Addenbrooke’s Hospital and an Associate Clinical disease (PVD) and interstitial lung disease. Her MD Lecturer at Cambridge University. She is the Respiratory research was conducted in the largest PVD centre in the Training Programme Director for the East of England. UK and was focused on pulmonary arterial hypertension. Her main clinical interests include complex lung She admits she had a rather unusual course into infections, particularly in those with primary and respiratory medicine and feels privileged to be working secondary immunodeficiency. She also manages in this field. She is also a mother to two little boys who patients with tuberculosis and non-tuberculous are by far her proudest achievements. #RespisBest mycobacteria. She has a longstanding interest in #Worklifebalance respiratory disease associated with haematological conditions including malignancy, and has established an Dr Paul Callan is a Consultant Cardiologist with a interest group in this area amongst colleagues within the specialist interest in heart failure, transplantation and BTS. She is working with European colleagues on a mechanical circulatory support at Wythenshawe proposal for ERS/EBMT/CIBMTR consensus guidelines on Hospital, Manchester. His day-to-day role focuses on treatment of pulmonary chronic graft versus host the care of patients with advanced heart failure, and the disease. longer-term care of patients following heart transplant or left ventricular assist device implantation. He qualified How do I approach a haemato-oncology patient? More from the University of than just a BAL? Manchester in 2004, and undertook the majority of his In this brief presentation, I hope to cover some basic postgraduate training in Yorkshire. He developed his principles of approaching a: passion for heart failure as a cardiology registrar in Hull, 1) haemato-oncology inpatient with lung infiltrates or and undertook an advanced heart failure fellowship in fever, discussing the role of bronchoscopy and fungal Harefield Hospital. He has an MD from Hull for research biomarkers; into mitochondrial dysfunction in cardio-renal syndrome, 2) patient with complications of bone marrow/stem cell and was awarded an MSc in clinical trials from the transplantation, outlining potential infectious and non- University of London. infectious complications such as lung GVHD; 3) haemato-oncology patient with recurrent respiratory Cardiovascular complications of respiratory disease infection in clinic, discussing the importance of imaging, Cardiovascular conditions are highly prevalent in microbiology and immunological assays and where patients with chronic lung disease, and are a common antimicrobial prophylaxis and immunoglobulin cause of morbidity and early mortality, particularly in replacement fit in. patients with less severe lung disease. The talk will highlight the importance of multi- There are often shared aetiological factors, such as disciplinary working/communication in order to provide smoking, exposure to air pollution and obesity. The optimal care to this patient group. underlying lung disease itself may contribute to the

Speakers’ Details & Presentation Summaries

th th SUMMER MEETING ONLINE – 17 & 18 June 2021

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OPEN SESSION – NCEPOD STUDY INTO LONG TERM VENTILATION IN THE UNDER 25s Friday 18th June: 10:15-10:45

Dr Mark Juniper has been a Consultant in Respiratory and Intensive Care Medicine in Swindon since 2000. He has been Clinical Co-ordinator at the National Confidential Enquiry into Patient Outcome and Death (NCEPOD) since 2012. He was an author of the NCEPOD studies on acute non-invasive ventilation and the study presented at the BTS Summer Meeting 2021 meeting on long term ventilation in children and young people.

NCEPOD study into long term ventilation in the under 25s This report looks at the care of children and young people receiving both invasive and non-invasive long- term ventilation at home. Demographic data from patients receiving LTV across the UK have been collected. Data was collected on the experience of patients, carers and healthcare professionals who deliver LTV services. A sample of patients was also taken for in-depth review of the care provided. Data from all of these sources was used to inform recommendations to improve LTV care. Data and recommendations from the report will be presented at the meeting.

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th th SUMMER MEETING ONLINE – 17 & 18 June 2021

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GUEST LECTURE – UPDATE ON THE LONG-TERM PLAN Friday 18th June: 11:00-11:50

Professor Jon Bennett. From a non-medical Professor Andrew Menzies-Gow is the Director of the background, Jon still has to pinch himself about how Lung Division at the Royal Brompton Hospital and a lucky he was to have found medicine, even in our Professor of Practice (Respiratory Medicine) at strange COVID-19 and post COVID-19 world. He is Imperial College where his research interests include grateful to have found respiratory medicine and to novel therapies for severe asthma and eosinophilic have had great support from the BTS and his lung disease. He is the National Clinical Director for respiratory colleagues throughout his career. Jon has Respiratory Disease for NHS England and been a consultant since 2000, firstly in Derby, and Improvement and Chair of the Adult Specialised then from 2004 in the nationally renowned Glenfield Respiratory Clinical Reference Group for NHS England Hospital where he continues to age disgracefully. Specialised Commissioning. Jon is a COVID-19 survivor – swab negative – terrible self-technique, antibody positive. He can be seen doing his bit for the environment; cycle commuting Update on the Long-Term Plan most days to and from Glenfield Hospital. As a native The presentation will cover the ambitions of the Long- Wulfrunian, he has the curse of supporting the mighty Term Plan to transform the outcomes of people with Wolverhampton Wanderers. respiratory disease, including enhancing early and Clinical interests include: lung cancer, interventional accurate diagnosis, medicine optimisation and respiratory procedures, medical education, general increased availability of pulmonary rehabilitation. The respiratory medicine. impact of the COVID-19 pandemic on respiratory services and the opportunities to transform outcomes as we ‘build back fairer’ will be discussed in detail.

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th th SUMMER MEETING ONLINE – 17 & 18 June 2021

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MINI SHORT COURSE – LUNG CANCER (PART 1): MDT MANAGEMENT Friday 18th June: 12:00-13:30

Case presentations Decisions about treatments for lung cancer are Miss Begum's areas of expertise include: adult and becoming more complex due to co-morbid conditions paediatric thoracic surgery; surgery for primary lung and changing treatment paradigms. This session aims cancer including lobectomy and segmentectomy to highlight some challenging clinical cases, using an performed via a uniportal video-assisted expert panel to discuss current evidence-based thoracoscopic surgery (VATS) approach; primary and guidance, consider areas of uncertainty and review metastatic chest sarcoma; surgery for advanced the most appropriate management options. emphysema; surgery for pneumothoraces and pleural effusions; surgery involving the mediastinum; and Dr Emma O’Dowd is a Consultant Respiratory airway stenting. Physician at Nottingham University Hospitals NHS Miss Begum’s research interests include lung volume Trust. reduction surgery, minimally invasive surgery for She was awarded a PhD in lung cancer epidemiology early-stage lung cancer, and chest wall sarcomas. She entitled “Factors influencing the diagnosis and is currently overseeing the development of a web- subsequent prognosis in patients with lung cancer” in based patient education platform. 2017, funded by the Roy Castle Lung Cancer Foundation. Her research interests are lung cancer Professor Richard Booton has been Consultant screening, early diagnosis and epidemiology of lung Respiratory Physician in the North West Lung Centre cancer. She is a member of the National Cancer for 12 years and Clinical Director for Lung Cancer and Research Institute Screening, Prevention and Early Thoracic Surgery at Wythenshawe Hospital, Diagnosis Group and the British Thoracic Society Lung Manchester since 2018. He was awarded an Honorary Cancer and Mesothelioma Specialist Advisory Group. Chair in Respiratory Medicine at the University of Manchester. Miss Sofina Begum received her medical degree from Professor Booton graduated from the University of the University of Leicester in 2004. During that time, Leeds and completed higher specialist training in the she finished an intercalated BSc in cardiovascular North West followed by a fellowship in thoracic science and went on to complete her basic surgical oncology at the Christie Hospital and Paterson training in London. Institute for Cancer Research with Professor Nick Miss Begum achieved her master's degree in surgical Thatcher, receiving a PhD in 2006. He is Programme science then went on to higher surgical training in Director for the award-winning RAPID programme and Yorkshire. This included training in uniportal minimally Manchester Lung Health Check/Lung Cancer invasive surgery (keyhole) for lung cancer and lung Screening programme. volume reduction. She is also trained in endobronchial Professor Booton has additional affiliations/ procedures for airways disease and severe memberships with the British Thoracic Oncology emphysema. Group, the Council of Regents, the Communications Since 2017, Miss Begum has been a consultant at Committee for the International Association for the Royal Brompton Hospital. Study of Lung Cancer, the Clinical Advisory Group of the National Lung Cancer Audit, and the NHSE National Delivery Group for Lung Health Checks.

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th th SUMMER MEETING ONLINE – 17 & 18 June 2021

Speakers’ Details and Presentation Summaries The following details are in programme order. Use the PDF search button to quickly find a session or speaker.

Dr Alice Davies is an ST6 NW Thames Respiratory Kath Hewitt is Matron, Lung Cancer, North West trainee. She graduated from the University of Nightingale Hospital, Wythenshawe, Trafford, Sheffield Medical School in 2010 and then moved to Withington and Altrincham Hospitals, Manchester London to continue her training. She has a special University Foundation Trust. interest in lung cancer and pleural disease and has been a trainee representative on the BTS SAG on Lung Dr David Woolf is a Consultant Clinical Oncologist at Cancer and Mesothelioma since 2017. She recently The Christie in Manchester, UK. completing a PhD under Professor Sam Janes at Lungs During his career, Dr Woolf has had over 20 for Living UCL Respiratory on a novel cell and gene publications in peer reviewed journals, published therapy for metastatic lung cancer and has a book chapters as well as over 40 oral and poster continued interest in early phase clinical trials. presentations to national and international conferences. These include multiple publications and Dr Joanne Heaton studied medicine at the University presentations in the field of breast and lung cancer. of Liverpool and since qualifying has worked across Dr Woolf also runs regular teaching sessions for junior Merseyside in various hospitals. She has recently doctors. He examines on The Christie FRCR been appointed to a consultant post at St Helens and examination course and has worked extensively with Knowsley Hospital Trust. Joanne has a specialist the Royal College of Radiologists to enhance training interest in lung cancer and has been a member of the for clinical oncologists. BTS SAG for Lung Cancer and Mesothelioma since Dr Woolf plans and delivers radiotherapy at The 2018. She also has an interest in medical education Christie to patients with breast and lung cancers and and doctors in training and is a training lead for her also gives Stereotactic Ablative Radiotherapy (SABR) speciality in her trust. for lung cancers and oligometastases (cancers that have spread to the lungs). In addition, he gives hormone therapy (endocrine therapy), chemotherapy and targeted drugs.

Speakers’ Details & Presentation Summaries

th th SUMMER MEETING ONLINE – 17 & 18 June 2021

Speakers’ Details and Presentation Summaries The following details are in programme order. Use the PDF search button to quickly find a session or speaker.

JOINT BTS/ARTP SYMPOSIUM – PHYSIOLOGY ASSESSMENT OF THE BREATHLESS PATIENT Friday 18th June: 12:00-13:30

SESSION SUMMARY Vicky is Chair of the ARTP Education Committee and a Physiology is a keystone of respiratory medicine but it is member of the ERS Spirometry Committee. often poorly understood. Feedback from the respiratory SCE examination suggests that this is an area where Assessing the breathless patient at rest questions are often answered poorly and candidates This presentation aims to walk you through the tests struggle. Other respiratory professionals such as nurses available in your lung function laboratory and within and physiotherapists also often struggle to find good your clinic, which you might consider using when sources of learning. assessing a breathless patient at rest. The pros and cons This session will illustrate where simple and more of each will be explained and illustrated using case complex respiratory function tests can be used to studies. This talk should set the background for the confirm or exclude expected diagnoses and sometimes session. provide additional information on the breathless individual. This session is aimed at earlier year Dr Martin Johnson is Consultant Physician and Director respiratory trainees and other respiratory professionals, of the Scottish Pulmonary Vascular Unit (SPVU) at the although it will provide a refresher for more senior Golden Jubilee National Hospital in Glasgow. He is also respiratory doctors. an Honorary Associate Clinical Professor with the University of Glasgow within the Institute of Dr Karl Sylvester is Head of Joint Respiratory Physiology Cardiovascular and Medical Sciences and is clinical lead at both Cambridge University Hospitals and Royal for the pulmonary function laboratories in North West Papworth Hospital NHS Foundation Trusts. He is Chair of Glasgow including the West of Scotland Heart and Lung Group 9.01 at the European Respiratory Society, a group Centre. which represents respiratory and sleep scientists from Dr Johnson’s research interests include pulmonary across Europe. His specialist interest is the performance hypertension and cardiopulmonary physiology, in and interpretation of cardio-pulmonary exercise testing. particular in application to exercise testing and exercise He is faculty lead for the ARTP’s annual CPET course and training. faculty member for the UCLA/Cambridge CPET course. Dr Sylvester initially joined Cambridge University Assessing the breathless patient on exercise Hospitals after completing a PhD investigating The aims of this presentation are to give the audience a respiratory complications in patients with sickle cell wider understanding of: disease. - how pathophysiology leads to excessive breathlessness during exercise; Mark Unstead is Lead Respiratory Physiologist, Royal - how exercise can be optimally used to diagnose the Berkshire NHS Foundation Trust, Reading, underlying cause of breathlessness, to predict prognosis Berkshire. Current interests are early physiological and to assess the response to treatment. detection of lung disease and novel methods of monitoring long term conditions. Dr James Hull is Respiratory Physician at the Royal Brompton Hospital. He also leads the Sport Respiratory Dr Vicky Moore is the Clinical Scientist for the Service at the Institute of Sport, Exercise and Health Occupational Lung Disease Service at University (ISEH), UCL, London and is currently lead respiratory Hospitals Birmingham and deputy manages the advisor to the English Institute of Sport. He has recently Respiratory Physiology Department at Heartlands chaired a new clinical statement on respiratory issues in Hospital. She specialises in specific inhalation challenge athletic individuals for the British Thoracic Society. testing, workplace visits and serial peak flow analysis for the diagnosis of occupational asthma. She Breathlessness in the athlete completed her PhD in 2010 and continues to be actively This talk will cover everything you need to know about involved in research. the assessment of the breathless athlete.

Speakers’ Details & Presentation Summaries

th th SUMMER MEETING ONLINE – 17 & 18 June 2021

Speakers’ Details and Presentation Summaries The following details are in programme order. Use the PDF search button to quickly find a session or speaker.

SYMPOSIUM – BRINGING QUALITY IMPROVEMENT TO LIFE Friday 18th June: 12:00-13:30

Dr Susannah Bloch is a Consultant in Respiratory Dr Daniel Smith is a Respiratory SpR at Nottingham Medicine, St Mary’s Hospital, Imperial College, University Hospitals. His current role is a National London. She is the lead for NIV and also leads the lung Medical Director’s Clinical Fellow working for NHS cancer MDT for Imperial. She has been involved in England and Improvement and for the Emergency setting up a new acute respiratory unit for NIV Care Improvement Support Team (ECIST) for NHS patients and level 2 respiratory care including on the Improvement. Daniel is a member of the BTS QI respiratory ward. She has run QI projects for NIV care committee and has a special interest in improving and is involved in the BTS NIV QI tool kit. She trained clinical pathways utilising quality improvement at Imperial College Medical School and did her PhD at methodology and has previously presented on the Royal Brompton in critical care with the muscle successful programmes improving the care of patients lab, and has ongoing interests in muscle weakness in requiring acute non-invasive ventilation. critically ill patients. Quality improvement in NIV Quality improvement – why you can’t live without it Dr Daniel Smith will share his experience in leading Reflections on NIV QI projects and QI moving forward quality improvement programmes to improve acute in a post COVID-19 era. non-invasive ventilation services and highlight the work of other teams. He will demonstrate how the BTS Quality Standards for acute NIV provide an excellent basis for inspiring QI and how utilising techniques including continuous data collection and PDSA cycles can lead to sustainable change.

Speakers’ Details & Presentation Summaries

th th SUMMER MEETING ONLINE – 17 & 18 June 2021

Speakers’ Details and Presentation Summaries

RESEARCH DROP-IN OPEN SESSION Parallel session 1: PICO development for the HTA process Friday 18th June: 13:45-14:15

Professor Anthony de Soyza is an Academic particularly the impact of intermittent hypoxia on the Clinician/Physician-Researcher and an Honorary brain. The aim of her research group is to translate Consultant Physician at Newcastle upon Tyne physiological research into improvements in patient Hospitals NHS Foundation Trust. He has undertaken care. Recently, she developed a UK respiratory-sleep UK Chief Investigator roles and recently started network facilitating multi-centre trials. The network international lead investigator roles. This maps to his has previously completed a trial to determine the role as National Specialty lead for the NIHR National impact of treating OSA in older people, and more Respiratory Group working for the UK National recently the treatment of mild OSA. Professor Morrell Institute for Health Research Clinical Trials Network. has served on the American Thoracic Society Board of He has recently taken on Chair of the NIHR Health Directors, the Physiological Society Executive Board Technology Assessment in Hospital medicine and she is a Past-President of the British Sleep Society. prioritisation panel and welcomes discussion on the HTA! Dr Sophie West is a Respiratory Consultant at Newcastle upon Tyne NHS Foundation Trust and leads Professor John Hurst is Professor of Respiratory the Newcastle Regional Sleep Service. Her research Medicine at University College London, and Honorary interests are in OSA and the impact of CPAP on co- Consultant Respiratory Physician at Royal Free London morbid conditions, such as insulin resistance, type 2 NHS Foundation Trust. He is National Lead for COPD diabetes and diabetic retinopathy. She is on the NICE with the Royal College of Physicians National Asthma Sleep Disordered Breathing Clinical Guidelines and COPD Audit Programme. John is Editor in Chief of committee. With the OSA Partnership group, she has the European Respiratory Monograph. He is currently a keen interest in ensuring accurate driving advice to a member of BTS Council. His clinical and research people with OSA. interests centre on exacerbations of COPD. He is Deputy Chair of the National Institute for Health Session overview Research CRN National Respiratory Group. This session follows on from the “Pathways to research for respiratory professionals” session held on Professor Mary Morrell is Professor of Sleep and Thursday. This is an open session and provides the Respiratory Physiology, National Heart and Lung opportunity to meet experienced researchers and Institute, Royal Brompton Hospital, Imperial College discuss some of the key questions that enhanced London. Her research focuses on the causes and collaborative research could answer, and learn more consequences of sleep disordered breathing; about PICO questions.

Speakers’ Details & Presentation Summaries

th th SUMMER MEETING ONLINE – 17 & 18 June 2021

Speakers’ Details and Presentation Summaries

RESEARCH DROP-IN OPEN SESSION Parallel session 2: Developing local trainee and research networks Friday 18th June: 13:45-14:15

Dr Alex Dipper is a South West based Respiratory Dr Akhilesh Jha is a Clinical Lecturer in Experimental Registrar and Clinical Research Fellow at the Academic and Respiratory Medicine at the University of Respiratory Unit, North Bristol NHS Trust. She is Cambridge. His research uses human challenge undertaking a PhD in the management of malignant models to investigate innate immunity to viral pleural effusions. She is co-chair of the PRISM infection and its dysregulation in airway disease, for Respiratory Trainee Research Network, established in which he was awarded the Royal Society of Medicine’s 2017 and the first respiratory collaborative trainee Young Respiratory Investigator Award. He is a research network in the UK. member of the BTS Science and Research Committee and a Junior Editor-in-Training for the American Dr Rob Hallifax is an NIHR Academic Clinical Lecturer Journal of Respiratory and Critical Care Medicine. He at the University of Oxford. He studied an MSc in is keen to develop a national network of respiratory Natural Sciences in Cambridge before training in early career professionals for collaborative research medicine at the University of Oxford. He won an MRC projects. Clinical Training Fellowship for his DPhil, "Understanding pneumothorax: epidemiology, Session overview physiology and outcomes", and led the RAMPP This session follows on from the “Pathways to (Randomised Ambulatory Management of Primary research for respiratory professionals” session held on Pneumothorax) study – a multi-centre trial of 24 sites Thursday. This is an open session and provides the around the UK. Results are published in JAMA and opportunity to meet experienced researchers and Lancet. Rob is trained in thoracoscopy, advanced discuss some of the key questions that enhanced pleural ultrasound and clinical trials methodology. collaborative research could answer, and learn more about PICO questions. Dr Karen Heslop-Marshall is a Nurse Consultant working in Newcastle upon Tyne. Karen’s main area of expertise is the psychological impact of respiratory disease. Karen completed a postgraduate diploma in cognitive behavioural therapy (CBT) in 2003 and developed a CBT treatment for patients with respiratory problems who face psychological difficulties. Karen completed a National Institute of Health Research (NIHR) PhD Clinical Academic Training Research Fellowship from 2011 to 2016. Her PhD research was the largest RCT into CBT for COPD patients who experience anxiety and depression. Karen was a co-applicant of the NIHR TANDEM HTA Study using CBT and pulmonary rehabilitation.

Speakers’ Details & Presentation Summaries

th th SUMMER MEETING ONLINE – 17 & 18 June 2021

Speakers’ Details and Presentation Summaries

RESEARCH DROP-IN OPEN SESSION Parallel session 3: Designing and developing research ideas Friday 18th June: 13:45-14:15

Dr Swapna Mandal is a Consultant Respiratory Physician at data to inform translational science. Liz’s translational the Royal Free London NHS Foundation Trust. She has a science focuses on neutrophil biology, strongly implicated sub-specialist interest in sleep and ventilation. She has in ageing and COPD related tissue damage and poor spent four years pursuing research in this field at a bacterial clearance. renowned sleep and ventilation centre, particularly in individuals with obesity and sleep disordered breathing. Professor Dinesh Saralaya is currently a Consultant She has also been leading the post-COVID follow up of Respiratory Physician and Honorary Senior Lecturer at hospitalised patients. Bradford Teaching Hospitals NHS Foundation Trust and Director for the NIHR Patient Recruitment Centre in Professor Najib M Rahman, Professor of Respiratory Bradford. He leads the severe asthma service at Bradford Medicine, Lead for Pleural Diseases, Director, Oxford Teaching Hospitals NHS Foundation Trust. Dinesh is also the Respiratory Trials Unit, University of Oxford and Oxford National Clinical Lead for Industry for the Respiratory Centre for Respiratory Medicine, Churchill Hospital, Oxford, Disorders Speciality Group, NIHR and Clinical Divisional Deputy National CRN Lead for Respiratory Disease, NIHR Lead for Industry at the Yorkshire and Humber Clinical CRN. Research Network. Having qualified in Oxford, Najib underwent the medical Dinesh leads the Respiratory Clinical Trials unit at BIHR. This SHO rotation at Queen’s Medical Centre, Nottingham, and unit has grown to become one of the largest self-funded re-joined Oxford as a Specialist Registrar in 2003. He respiratory clinical trials in the UK. The unit is one of the top undertook a DPhil and MSc in this period and was 5 most reliable and experienced severe asthma clinical appointed Director of the Oxford Respiratory Trials Unit research units in the UK. He has been the chief co- and Consultant Lead for Pleural Disease in Oxford in ordinating investigator in the UK for several multi-national 2011. He was appointed as Professor of Respiratory phase 2 and 3 severe asthma and COPD trials. The Unit has Medicine in 2018, and is currently running randomised and recruited several Global and European first patients into observational studies in pleural infection, pneumothorax these trials. The unit attracts patients for its clinical trials and malignant pleural effusion. Najib is trained in programme from across the Yorkshire region. The unit has thoracoscopy, thoracic ultrasound and clinical trials well established links with all major pharmaceutical methodology, and has published over 250 papers with companies as well as major clinical trials organisations. He citations of >6000. He is Co-chair of the BTS Pleural has particular interest in inhalation profiles in patients with Guidelines 2021, Chair of the BTS Pleural Intervention severe asthma and COPD and has published his work in this Committee, and Chair of multiple ERS guidelines on pleural field. disease. He is Deputy Chair of the National Institute for In 2015 and 2016 Dinesh was awarded the best Principal Health Research CRN National Respiratory Group. Investigator award for the UK for his delivery into the commercial respiratory research portfolio by NIHR. In 2019 Professor Elizabeth Sapey is the Chair of the British Dinesh was awarded the NIHR/RCP Award for research in Thoracic Society Science and Research Committee. She is the UK. He is Industry Lead for the National Institute for an academic respiratory physician at the University of Health Research CRN National Respiratory Group. Birmingham, Director of the HDR-UK Health Data Research Hub in Acute Care, PIONEER and the Managing Director of Session overview Birmingham’s NIHR Clinical Research Facility. Liz’s research This session follows on from the “Pathways to research for interests focus on inflammatory respiratory diseases respiratory professionals” session held on Thursday. This is associated with ageing, and the impact of inflammation in an open session and provides the opportunity to meet an ageing host. Her interests span translational experienced researchers and discuss some of the key science, moving new or repurposed therapies into early questions that enhanced collaborative research could phase clinical trials and using routinely collected health answer, and learn more about PICO questions.

Speakers’ Details & Presentation Summaries

th th SUMMER MEETING ONLINE – 17 & 18 June 2021

Speakers’ Details and Presentation Summaries

MINI SHORT COURSE – LUNG CANCER (PART 2): BEYOND THE MDT Friday 18th June: 14:30-16:00

Dr Vidan Masani is a Consultant Respiratory Physician in Side effects of systemic anti-cancer therapy the Royal United Hospital, Bath, where he was appointed in Overview of current SACT in lung cancer. Toxicities related 2004 after graduating from The Royal Free Hospital School to chemotherapy, immunotherapy and targeted therapies. of Medicine. He is the current Chair of the BTS Lung Cancer Learning aimed at the non-oncological specialist, allowing and Mesothelioma Specialist Advisory Group. identification of complications presenting to a general medical admissions unit. Dr Yvonne Summers studied undergraduate medicine at the University of St Andrews and the University of Dr Laura Cove-Smith is Consultant Medical Oncologist at Manchester, graduating in 1993, and subsequently The Christie NHS Foundation Trust and Manchester completed higher specialist training in medical oncology at University Foundation NHS Trusts, specialising in thoracic the Christie Hospital, Manchester between 1997 and 2004. malignancies, acute oncology and CUP. During this period, she was awarded a doctorate for She studied undergraduate medicine at Sheffield University research in the field of stem cell biology. then moved to Manchester in 2007 to specialise in medical In 2004 she commenced her first post as Consultant oncology at The Christie NHS Foundation Trust. During this Medical Oncologist in the Northern Ireland Cancer Centre, time, she was awarded a PhD from the University of Belfast, where she concentrated her efforts on establishing Manchester (Cancer Research UK Manchester Institute) in a medical oncology service for lung cancer patients and the field of circulating and imaging toxicity biomarkers and introducing clinical trial research. developed an interest in late effects from cancer therapy. She returned to Manchester in 2009, where she specialises She took up post as a medical oncology consultant in thoracic oncology and is Clinical Director for Medical specialising in thoracic and acute oncology at The Christie Oncology at the Christie Hospital. NHS Foundation Trust and Wythenshawe Hospital in 2018. In addition to the clinical service, she has experience as UK Her research interests include running phase III clinical chief investigator and principal investigator in commercial trials focusing on early lung cancer and mesothelioma and and academic clinical studies. She influences lung cancer improving outcomes for patients living with and beyond research and treatment through work with NHS England’s cancer. Lung Cancer Clinical Expert Group (CEG) and as a clinical expert for NICE technology appraisals and was a previous Jackie Fenemore qualified as an RGN in 1995 and has member of the NIHR Clinical Studies Group (CSG) and Chair worked at The Christie Hospital, Manchester for over 20 of the LORD Subgroup of the Lung CSG and previously years. Jackie worked as a lung cancer nurse specialist from chaired the Christie Drugs and Therapeutics Committee. 2007-2017. After completing an MSc in Advanced Practice earlier this year, Jackie continues to work in the lung cancer Professor Samreen Ahmed is Consultant Medical team as a Lung Cancer Nurse Clinician and is the pathway Oncologist, University Hospitals of Leicester NHS Trust. nurse lead on the non-operable stage 3 curative concurrent Professor Ahmed has been a Consultant in Medical chemo-radiotherapy pathway. Jackie is a non-medical Oncology since 2006 and qualified in 1994 at the Royal Free prescriber and is on the committee for the Lung Cancer Hospital School of Medicine, London (UK). She has a Nurses UK (LCNUK), currently acting member on the research degree (MD) through Nottingham University and steering committee for the Clinical Expert Group in Lung undertook oncology training in Weston Park Hospital Cancer and a member of the Global Lung Cancer Coalition (Sheffield), Nottingham City Hospital and the Leicester (GLCC). Royal Infirmary. She is a Fellow of the Royal College of Physicians. Appointed Honorary Chair of Medical Oncology Symptom control in lung cancer by University of Leicester in 2016. The presentation will cover common side effects such as Professor Ahmed is Honorary Secretary for the Association breathlessness, cough, cachexia, pain, haemoptysis, hoarse of Cancer Physicians (ACP) and Steering Committee voice, lethargy and best ways to manage these and to Member for the British Thoracic Oncology Group (BTOG). prepare people to cope with treatment. Professor Ahmed is the Training Programme Director for Medical Oncology. She is Chief Investigator and local Principal Investigator for a number of clinical trials in breast and lung cancer.

Speakers’ Details & Presentation Summaries

th th SUMMER MEETING ONLINE – 17 & 18 June 2021

Speakers’ Details and Presentation Summaries

SYMPOSIUM – GROWING OLDER WITH NEURO-MUSCULAR DISEASE Friday 18th June: 14:30-16:00 (UWE). Her substantive post is as the Respiratory Pathway Alison Armstrong, Nurse Consultant (Long Term Lead Physiotherapist at University Hospitals Bristol and Ventilation) Newcastle upon Tyne. Weston NHS Foundation Trust. Her area of clinical expertise Alison is the Nurse Consultant within the regional North- and interest is ventilation, weaning and complex airway East Assisted Ventilation Service. She represents nursing clearance. on a number of groups. She has a national role as Co-chair Having completed the Advanced Cardiorespiratory for the BTS Nurse Specialist Advisory Group, as well as Physiotherapy MSc programme at University College being an active member on their Education and Training London (UCL) in 2012, Ema has continued her research Committee. focusing on the use of Mechanical Insufflation-Exsufflation Alison is the host of the Specialists in Long-term Ventilation (MI-E) and other cough augmentation strategies. Her at Home (SiLVaH) National Network, which is a non-medical current PhD work focuses on the use of MI-E in the group for those working in the support of patients on home intubated population. mechanical ventilation. Extra-curricular activities include contributions to the Alison has an MSc in Practice Development, and her main Undergraduate Physiotherapy programme at UW, and post- interest lies in assuring good quality of life for her complex graduate teachings at University College London. She sits client group. on the BTS Education and Training Committee, PHE Independent High-Risk Aerosol Generating Procedures Dr Mark Elliott is a Consultant Physician in Respiratory Panel, ICS WARE project as the AHP representative and is Medicine at St James's University Hospital, Leeds. He has the ongoing Chair of the Association of Chartered been responsible for developing the home sleep and Physiotherapists in Respiratory Care. assisted ventilation service, for acute in-hospital NIV and weaning of patients with prolonged ventilator dependence Airway clearance: the importance of cough at St James's University Hospital. He has research interests This presentation will consider the integral role of cough in acute and chronic NIV and OSA. augmentation across the neuromuscular lifespan. We will Dr Elliott was President of the British Thoracic Society 2018- examine the expanding evidence base and discuss how 2019, and Treasurer of the European Respiratory Society emerging evidence is changing our use of devices to benefit (2013 to 2016). He was a core member of the Guidelines this complex patient group. Writing Group for both the BTS (2016) and ERS/ATS Acute NIV Guidelines (2017) and the ERS guidelines on long-term Dr Ben Messer is a Consultant in Intensive Care Medicine home NIV for management of COPD (2019) and Home Ventilation in Newcastle upon Tyne and the clinical lead of the North East Assisted Ventilation Service. Management of respiratory failure in patients with chest His critical care interests are acute non-invasive respiratory wall deformity and neuro-muscular disease support and sepsis pathways. Within home ventilation, his The educational aims of this presentation are to interests are tracheostomy ventilation, secretion understand: management and palliative care in MND, and the 1) how to identify patients at risk for nocturnal respiratory and perioperative care of neuromuscular hypoventilation; patients. He is also his Trust’s Sepsis Lead. 2) how to monitor them before and after starting domiciliary NIV; Co-morbidities and other complications, including the 3) choice of ventilator, settings and adjustment; challenges of COVID-19 4) the importance of secretion management in addition to The learning objectives for this presentation are to show NIV. the range of co-morbidities that exist within the The presentation will cover the evidence base for the use of neuromuscular disease (NMD) patients, the impact on their NIV in these conditions and will give practical guidance, clinical management and the impact of COVID-19 on these both to those for whom NIV is their sub specialty focus but patients. also to respiratory practitioners with other sub specialty The presentation will cover: interests but who will come across these patients as part of ● life expectancy in NMD; their general respiratory work ● less well-recognised respiratory issues in NMD; ● other organ systems in NMD; Ema Swingwood is currently a NIHR Clinical Academic ● ventilatory withdrawal in NMD; Research Fellow at the University of the West of England ● COVID-19 experience in NMD.

Speakers’ Details & Presentation Summaries

th th SUMMER MEETING ONLINE – 17 & 18 June 2021

Speakers’ Details and Presentation Summaries

SYMPOSIUM – DIAGNOSTIC AND MANAGEMENT DILEMMAS IN PULMONARY VASCULAR DISEASE Friday 18th June: 14:30-16:00

Dr Colin Church is a Consultant in Pulmonary Vascular Dr Laura Price is a Consultant Respiratory Physician and Respiratory Medicine. He trained in Glasgow, and a full time NHS consultant in the National Cambridge, Papworth and Sydney. He has completed Pulmonary Hypertension (PH) Service at the Royal a PhD in understanding the basic mechanisms of Brompton Hospital. Completing undergraduate inflammatory signaling in pulmonary vascular training at the University of Bristol, she trained in remodeling. He has a keen interest in both clinical and respiratory medicine in NW Thames, also in general basic science research and is a principal investigator medicine, anaesthesia and ICU. She completed a PhD on a number of important clinical trials including at Imperial College and South Paris University on looking at novel anti-inflammatory strategies to treat ‘Inflammation in PAH’. She has clinical and research pulmonary hypertension. His basic science research interests in PH in lung disease, PVOD, pulmonary focuses on the interplay of inflammation and hypoxia thromboembolic disease, and the acute care of on the pulmonary vascular cells in particular the patients with PH including severe COVID-19. She also pulmonary artery fibroblast. runs a pulmonary vascular COVID-19 follow up clinic Dr Church is one of three consultants in the Scottish at RBH. Pulmonary Vascular Unit, which is the national referral centre for the Scottish population. This Unit Pulmonary hypertension and lung disease: when to investigates and manages all patients in Scotland with look for it and what can be done? pulmonary hypertension. He is also one of the Dr Price will talk at the BTS Summer Meeting 2021 principal clinicians involved in management of venous about the detection and management considerations thromboembolic disease in the Queen Elizabeth in patients with pulmonary hypertension (PH) University Hospital and sits on the Glasgow associated with lung disease (‘group 3 PH’). She will Thrombosis Committee. He is the educational cover essentials of the pathophysiology of group 3 PH, workforce leader for the International Society of Heart approaches to diagnosis, practical steps in and Lung Transplantation (ISHLT) and associate editor management, and when to consider referral to a PH for BMC Pulmonary Medicine. More recently he has centre. become the chair of the BTS Pulmonary Vascular Specialist Advisory Group. Twitter @acchurch1

Dr Sheila Ramjug is a Respiratory Consultant at Wythenshawe Hospital, Manchester Foundation Trust and has a specialist interest in pulmonary vascular disease (PVD) and interstitial lung disease. Her MD research was conducted in the largest PVD centre in the UK and was focused on pulmonary arterial hypertension. She admits she had a rather unusual course into respiratory medicine and feels privileged to be working in this field. She is also a mother to two little boys who are by far her proudest achievements. #RespisBest #Worklifebalance

Speakers’ Details & Presentation Summaries

th th SUMMER MEETING ONLINE – 17 & 18 June 2021

Speakers’ Details and Presentation Summaries

THE PHYSIOLOGY QUIZ

On demand throughout the Summer Meeting and Live Q&A session on Friday 18th June: 16:15-17:15

Quiz organised by the Respiratory Physiology Jessica Swan is Senior Respiratory Physiologist, Royal Department, Royal Berkshire NHS Foundation Trust Berkshire NHS Foundation Trust, Reading, Berkshire. Her current interests are cardiopulmonary Live question and answer session exercise testing and respiratory responses to altitude. Host: Mark Unstead Moderator: Jessica Swan Mark Unstead is Lead Respiratory Physiologist, Royal Berkshire NHS Foundation Trust, Reading, The Physiology Quiz will be available to access on Berkshire. His current interests are early physiological demand throughout the two days of the Summer detection of lung disease and novel methods of Meeting. Test your knowledge studying the individual monitoring long term conditions. cases, before revealing the answers. Leave questions for the quiz masters who will be on hand to chat during the open hours of the conference.

Then round off your Summer Meeting by joining the live question and answer session. During this live interactive hour, Mark and Jessica will discuss the most frequently asked questions and take new questions about the quiz case studies.

Speakers’ Details & Presentation Summaries