D2r18Cyc: Loktanella sp. D2R18 Cellular Overview glutamate glutamate asn asn spermidine cefoperazone gln uracil spermidine spermidine spermidine spermidine 4-amino-2-methyl-5- 4-amino-2-methyl-5- 4-amino-2-methyl-5- putrescine putrescine glucosyl-oleandomycin asp asp xanthine putrescine putrescine putrescine putrescine putrescine putrescine a dipeptide pyrimidinemethanol pyrimidinemethanol pyrimidinemethanol 4-amino-2-methyl-5- gln gln pyrimidinemethanol Spermidine predicted ABC predicted ABC predicted ABC Multidrug Glutamate/ Glutamate/ Glutamine Putrescine Putrescine ABC predicted predicted predicted predicted Putrescine Putrescine ABC-type transporter of 4- transporter of 4- transporter of 4- Hydroxymethylpyrimidine resistance glutamine/ glutamine/ transport Uracil- transport transporter ABC ABC ABC ABC transport transport dipeptide amino-2-methyl-5- amino-2-methyl-5- amino-2-methyl-5- ABC transporter, protein aspartate/ aspartate/ ATP- xanthine ATP- permease transporter transporter transporter transporter system system transport pyrimidinemethanol pyrimidinemethanol pyrimidinemethanol norM asparagine asparagine binding permease binding component potC of spermidine/ of spermidine/ of spermidine/ of spermidine/ permease permease system, protein protein (TC_3.A.1.11.1) putrescine putrescine putrescine putrescine

4-amino-2-methyl-5- cefoperazone 4-amino-2-methyl-5- 4-amino-2-methyl-5- 4-amino-2-methyl-5- pyrimidinemethanol glucosyl-oleandomycin glutamate glutamate xanthine spermidine spermidine spermidine spermidine putrescine putrescine a dipeptide pyrimidinemethanol pyrimidinemethanol pyrimidinemethanol asn asn uracil putrescine spermidine gln putrescine putrescine putrescine putrescine asp asp putrescine gln gln

Cofactor, Prosthetic Group, Electron Carrier, and Vitamin Biosynthesis Fatty Acid and Lipid Biosynthesis superpathway of glycolysis and the Entner-Doudoroff pathway C1 Compound Utilization and Assimilation UDP-N-acetyl-α-D- a [3-methylcrotonoyl- GlcNAc-1,6- a peptidoglycan 1-stearoyl- 3-oxo-2-(cis-2'-pentenyl) an N-terminal- (S)-3- (S)-3-hydroxy-(7Z) (11Z)-(S)-3- purine nucleotides degradation II (aerobic) Nucleoside and Nucleotide Degradation cob(II)alamin- a long-chain 2,3,4- an apo-[LYS2 L-2- an acyl-[acyl- ditrans,octacis- methylmalonyl- γ a (3Z)-dec-3-enoyl-[acp] a malonyl-[acp] biotin sn-glycerol CO 5'-deoxy-5'-fluoroadenosine -cyclopentane-1-(3R- a peptide β L-methionyl-L- a purine 2'- 4-tyrosol hydroxytetradecanoyl- hydroxyhexadec- superpathway of geranylgeranyl cob(II)yrinate a,c- pyridoxal 5'-phosphate biosynthesis I palmitate biosynthesis II (bacteria and plants) Amine and Polyamine Biosynthesis D-glucopyranose superpathway of pyrimidine superpathway of purine deoxyribonucleosides degradation guanosine nucleotides ATP [CblC-CblD saturated fatty acid coenzyme A muramoyl-L-alanyl- - D-alanyl-D-alanine CoA-carboxylase]-L-lysine anhMurNAc- dimer with undecaprenyldiphospho- -alanine -hexadecenoyl-CoA polyisoprenoid biosynthesis (E. coli) [2Fe-2S] iron-sulfur cluster biosynthesis cob(II)yrinate a,c-diamide superpathway of tetrahydrofolate biosynthesis superpathay of heme b superpathway of adenosylcobalamin salvage from cobinamide I thiamine salvage IV (yeast) biotin biosynthesis from 5-methoxybenzimidazolyl adenosylcobamide palmitoleate phosphatidylglycerol fatty acid elongation -- saturated (Kdo) -lipid A formaldehyde oxidation aminoadipyl-carrier-protein] γ carrier protein] diphosphate biosynthesis II (via MEP) 2 deoxyribonucleosides degradation degradation II formaldehyde oxidation CoA mutase Long-chain-fatty- Holo-[acyl-carrier D-glutamyl-L-lysine Biotin--protein ligase L-Ala- -D-Glu- pentapeptide 3-phosphate N-acetyl-(N- Carbon monoxide Purine nucleoside hydroxybutanoyl)-CoA seryl-[protein] deoxyribonucleoside Alcohol CoA 11-enoyl-CoA diamide biosynthesis I biosynthesis II (late 8-amino-7-oxononanoate I biosynthesis from adenosylcobinamide-GDP biosynthesis I (plastidic) 6-phosphate VII (THF pathway) complex] UDP-N- 3-oxoacyl-[acyl- 1-acyl-sn-glycerol- Enoyl-CoA Xaa-Pro Gamma- Methionine 3-hydroxyacyl- Enoyl-CoA biosynthesis from glutamate biosynthesis I (from biosynthesis I Cob(I)alamin acid--CoA ligase (EC 6.3.4.9, EC 6.3.4.10, DAP-D-AlaN-acetylmuramoyl- stems (meso- dehydrogenase: phosphorylase Purine dehydrogenase, D-glyceraldehyde (early cobalt insertion) D-erythrose glycine betaine biosynthesis 2'-deoxycytidine II (glutathione-dependent) protein] synthase acetylmuramoylalanyl- carrier-protein] 3-phosphate acetylglucosaminyl) aminopeptidase aminobutyrate:alpha- aminopeptidase hydratase predicted pyruvate cobalt incorporation) thiamine an acetoacetyl-[acp] (5Z)-dodec-5-enoate) α α AMP adenosyltransferase (EC 6.2.1.3): Long- EC 6.3.4.11, EC L-alanine (EC 2.4.2.1): hydratase [isoleucine nucleoside CoA IPP L-cysteine desulfurase 4-phosphate cob(II)inamide -Kdo-(2->4)- - putrescine biosynthesis I 2'-deoxyguanosine (EC 2.7.8.7): Holo- diaminopimelateN-acetylmuramoyl- acyltransferase muramoyl-L-alanyl- Carbon monoxide (EC 3.4.13.9) (EC 3.4.11.18) zinc containing [isoleucine ABC 3-phosphate uroporphyrinogen-III 8-amino-7-oxononanoate 5-methoxybenzimidazole DHAP an acetoacetyl-[acp] I (Gram-negative bacteria) formaldehyde D-glutamyl-2,6- synthase, KASI degradation] ketoglutarate dehydrogenase uroporphyrinogen-III GTP glu a (5Z)-dodec- Kdo-(2->6)-lipid IV GMP formaldehyde (EC 2.5.1.17): chain-fatty-acid- [acyl-carrier protein] 6.3.4.15): G1RHH-1824 amidase (EC containing)L-alanine γ-D-isoglutaminyl- dehydrogenase Purine nucleoside phosphorylase (EC 1.1.1.1) thiamine thiamine Adenosylmethionine-8- Glycerol-3- A 5-nucleotidase SurE (EC purine ribonucleosides degradation diaminopimelate--D- (EC 2.3.1.41): (EC 2.3.1.51): 1- (EC 4.2.1.17) / 3- : Xaa-Pro aminotransferase : Methionine (EC 1.1.1.35): 3- degradation] transporter 1-deoxy-D- Uroporphyrinogen- glutamate- Cob(I)alamin 3-oxoacyl-[acyl-carrier 5-enoyl-[acp] Cytidine 2'-deoxyadenosine 5-nucleotidase SurE (EC Cob(I)alamin -CoA ligase (EC 3.5.1.28): N- amidase (EC β medium chain phosphorylase (EC (EC 2.4.2.1) : Alcohol Isopentenyl- Cysteine Uroporphyrinogen- Thiaminase II amino-7-oxononanoate Nicotinate-nucleotide-- choline 3.1.3.5): 5-nucleotidase Purine nucleoside synthase (EC alanyl-D-alanine ligase 3-oxoacyl-[acyl- Biotin--protein acyl-sn-glycerol- N-( -D-asparaginyl)Cell division hydroxyacyl-CoA aminopeptidase (EC 2.6.1.19): Gamma- aminopeptidase hydroxyacyl-CoA (EC 4.2.1.17) / 3- of thiamine xylulose 5- III methyltransferase tRNA ligase: adenosyltransferase (EC protein] reductase (EC 3-oxoacyl- phosphate α arg deaminase 3.1.3.5): 5-nucleotidase adenosyltransferase acetylmuramoyl- 3.5.1.28): N- : Purine dehydrogenase, diphosphate desulfurase III methyltransferase GTP (EC 3.5.99.2): dimethylbenzimidazole -Kdo-(2->4)- Choline dehydrogenase a 5,10- Long-chain-fatty- (EC 6.3.2.10): UDP-N- carrier-protein] ligase (EC 6.3.4.9, 3-phosphate -L-lysyl-D-alanineprotein FtsI Carbon monoxide Purine nucleoside (EC 3.4.13.9) CDS (EC 3.4.11.18) hydroxyacyl-CoA phosphate 4-phospho- aminotransferase 1.1.1.100): G1RHH-1018 [acyl-carrier- dehydrogenase Biosynthetic arginine SurE (EC 3.1.3.5) CDS (EC 3.5.4.5) thymidine phosphorylase SurE (EC 3.1.3.5) CDS 4'-phosphopantetheinyl dehydrogenase aminobutyrate:alpha- nucleoside dehydrogenase (EC 2.1.1.107): delta- (EC 2.1.1.107): cyclohydrolase G1RHH-1889 2.5.1.17): Cob(I)alamin phosphoribosyltransferase α-Kdo-(2->6)- methylenetetrahydrofolate S-(hydroxymethyl) (EC L-alanine acetylmuramoyl- dehydrogenase phosphorylase zinc containing (EC dehydrogenase (EC 2.8.1.7) Thiaminase II (EC 2.6.1.62): protein] [NAD(P)+] (EC (EC 1.1.99.1): G1RHH-1942 Glucose-6- IMP : Cytidine (EC 2.4.2.1): adenosine acid--CoA ligase transferase entD acetylmuramoylalanyl- synthase, EC 6.3.4.10, EC 1-acyl-sn-glycerol- [Peptidoglycan (EC 1.1.1.35) / 3- Xaa-Pro ketoglutarate Methionine (EC Thiamin ABC synthase Uroporphyrinogen- isomerase Uroporphyrinogen-III I (EC 3.5.4.16) [+ 2 isozymes] D-erythronate adenosyltransferase (EC (EC 2.4.2.21): G1RHH-2709 [+ 3 isozymes] (lauroyl)-lipid IV decarboxylase (EC 5'-nucleotidase (EC Adenosine deaminase 5'-nucleotidase (EC glutathione amidase (EC L-alanine small chain phosphorylase , SufS (EC 3.5.99.2) CDS A ATP:Cob(I)alamin (EC 6.2.1.3): Long- D-glutamyl-2,6- 6.3.4.11, EC 6.3.4.15) synthetase] (EC 2.4.2.1): (EC 1.1.1.35) / Glu Adenosylmethionine-8- 1.1.1.94): Glycerol- Choline dehydrogenase phosphate 1- GMP Thymidine Purine nucleoside Methylenetetrahydrofolate (EC 2.7.8.-); 3-oxoacyl-[acyl- 3-phosphate hydroxybutyryl-CoA aminopeptidase aminopeptidase Alcohol thiamine transporter, thiamine (EC 2.2.1.7) III methyltransferase (EC 5.3.3.2): methyltransferase (EC type 2: GTP an L-glutamyl-[tRNA ] synthase, a 3-oxoacyl-[acp] 4.1.1.19): G1RHH-2085 3.1.3.5): G1RHH-2543 deaminase (EC 3.5.4.4): 3.1.3.5): G1RHH-2543 S-(hydroxymethyl) amidase (EC Gamma- (EC subfamily: ATP:Cob(I)alamin amino-7-oxononanoate 5-methoxybenzimidazole (EC 1.1.99.1): Choline dehydrogenase phosphorylase phosphorylase (EC tRNA-specific adenosine- dehydrogenase adenosyltransferase chain-fatty-acid- Holo-[acyl-carrier : Biotin--protein N-acetylmuramoyl- acyltransferase (EC 2.4.1.129) Purine nucleoside epimerase (EC dehydrogenase Enoyl-CoA 3-hydroxybutyryl- transmembrane : 1-deoxy-D- (EC a (3R)-3-hydroxybutanoyl-[acp] KASI (EC 3-phosphate agmatine Inosine-5'-monophosphate (EC 3.5.4.5) Adenosine deaminase guanosine UDP-N- carrier-protein] Carbon monoxide (EC 3.4.11.9) aminobutyrate:alpha- (EC 3.4.11.18) Isopentenyl- Cysteine [+ 2 isozymes] cyclohydrolase chorismate adenosyltransferase (EC 4-amino-2-methyl-5- 5-(2-hydroxyethyl) adenosylcobinamide-GDP Glucose-6- glutathione (EC 2.5.1.17): -CoA ligase (EC ligase (EC 6.3.4.9, EC L-alanine : Cell division phosphorylase (EC Purine hydratase CoA epimerase xylulose 5- ribotide phosphate 2.3.1.41): dehydrogenase dehydrogenase (EC 1.1.1.49) adenosine 5-nucleotidase SurE (EC dehydrogenase (EC CDS (EC 2.4.2.4) 34 deaminase (NADP+) (EC 1.5.1.5) / protein] synthase, synthase, KASII N-acetylmuramoyl- (EC 2.3.1.51): dehydrogenase: 5.1.2.3): Enoyl-CoA : Xaa-Pro : Methionine (EC 1.1.1.1) [+ 2 isozymes] diphosphate precorrin-1 I (EC 3.5.4.16) 2.5.1.17): ATP:Cob(I)alamin Adenosylmethionine-8- α α phosphate (EC 3.5.4.4) CDS Purine nucleoside dehydrogenase acetylmuramoylalanyl- a [methylcrotonoyl-CoA ketoglutarate [isoleucine (EC 5.1.2.3) desulfurase (3R)-3-hydroxy-2-oxo- pyrimidinemethanol -4-methylthiazole 3-oxoacyl- sn-glycerol 3-oxoacyl-[acyl- -D-Kdo-(2->4)- - (EC 1.1.99.1) CDS Arginase/agmatinase/ : Glucose-6- 3.1.3.5): 5-nucleotidase 1.1.1.205): Inosine- : Thymidine (EC 3.5.4.-): tRNA- Methenyltetrahydrofolate ATP:Cob(I)alamin a long-chain 2,3,4- alternative (EC (EC 2.3.1.179): amidase (EC L-alanine G1RHH-1918 protein FtsI Carbon monoxide 5-fluoro-5-deoxy-D- hydratase [isoleucine aminopeptidase aminopeptidase nucleoside : Alcohol phosphate precorrin-1 delta- type 2 Anthranilate amino-7-oxononanoate 3-hydroxyacyl-[acyl-carrier- phosphorylase Inosine-uridine preferring (EC 1.1.1.284): S- D-glutamyl-2,6- carboxylase]-biotin-N 6 -L-lysine a 1-stearoyl 2- aminotransferase Substrate- (EC 2.8.1.7) 4 phosphooxybutanoate adenosyltransferase (EC 3-phosphate carrier-protein] D-Kdo-(2->6)-lipid A betaine aldehyde formimionoglutamate phosphate 1- isomerase phosphorylase specific adenosine- cyclohydrolase (EC adenosyltransferase AMP diphosphate 2.7.8.7): G1RHH-1017 3.5.1.28): N- amidase (EC di-trans,octa-cis [Peptidoglycana peptidoglycan adenine phosphorylase dehydrogenase degradation] : Enoyl-CoA synthase Uroporphyrinogen- hydroxymethylpyrimidine Hydroxyethylthiazole aminotransferase Cobalamin synthase protein] dehydratase, [acyl-carrier- tRNA-specific adenosine- SurE (EC 3.1.3.5) CDS 5'-monophosphate 2'-deoxyuridine Purine nucleoside (EC 2.4.2.1): nucleoside hydrolase (EC saturated fatty acyl CoA diaminopimelate-- 3-oxoacyl-[acyl- acyl-carrier protein acyl-sn-glycerol dehydrogenase ribose 1-phosphate (EC 3.4.11.9) CDS (EC 2.6.1.19): Gamma- (EC 3.4.11.18) isomerase , SufS 7,8- synthase, synthase, KASI hydrolase: Arginase/ (EC 5.3.1.9) (hydroxymethyl) a [cobalamin (EC adenosylcobalamin- acetylmuramoyl- 3-hydroxyacyl-CoA an N-terminal (EC 2.4.2.1) (EC 4.2.1.17) / 3- hydratase specific Uroporphyrinogen- (S)-4-amino-5- Phosphoserine kinase: kinase (EC 2.7.1.50): (EC 2.7.8.26): FabZ form (EC 4.2.1.59) protein] dehydrogenase 5'-nucleotidase (EC dehydrogenase (EC (EC 2.4.2.4) CDS 34 deaminase (EC 3.2.2.1): Inosine-uridine 3.5.4.9): G1RHH-2555 a [cyanocobalamin a holo-[LYS2 L-2- carrier-protein] 3.5.1.28): N- -undecaprenyl dimer[+ 2 isozymes] (E. faecium medium chain a proteinogenic (EC 1.1.1.1) CDS biotin biotin III methyltransferase dihydroneopterin amidotransferase [corrinoid adenosyltranferase]-cob(II)inamide (EC 2.6.1.62): 3-oxoacyl-[acyl- Betaine aldehyde : Glucose-6- 34 deaminase (EC 3.5.4.-) 2'-deoxyinosine phosphorylase Purine nucleoside glutathione 3',5'-ADP D-alanyl-D-alanine 3-phosphate dehydrogenase a peptide aminobutyrate:alpha- met hydroxyacyl-CoA [isoleucine component 1-deoxy-D-xylulose oxopentanoate aminotransferase Hydroxymethylpyrimidine Hydroxyethylthiazole G1RHH-2708 synthase, (EC 2.3.1.41): agmatinase/ (EC trafficking triphosphate [methylmalonyl- aminoadipyl-carrier-protein] synthase, L-alanine acetylmuramoyl- diphosphate , tetrapeptide) Carbon monoxide amino acid L-seryl-[protein] : Purine (4-hydroxyphenyl) III methyltransferase DMAPP Cysteine (EC 2.1.1.107): 3'-triphosphate component (EC Adenosylmethionine-8- : 3-hydroxyacyl- carrier protein] : tRNA-specific adenosine- 3.1.3.5): G1RHH-2543 Inosine-5'-monophosphate thymine (EC 2.4.2.1): phosphorylase (EC Adenosine deaminase preferring nucleoside Methylenetetrahydrofolate dehydrogenase reductase CblC] ligase (EC 6.3.2.10) γ N-acetyl-β-D- (EC 1.1.1.35): 3- ketoglutarate BioY of 5-phosphate (EC 2.6.1.52): phosphate kinase kinase (EC 2.7.1.50) 3-oxoacyl-[acyl- dehydrogenase (EC formimionoglutamate phosphate Purine nucleoside protein CblD] CoA mutase] L-alanyl- -D- amidase (EC L-alaninea peptidoglycan nucleoside acetaldehyde dehydrogenase (EC 2.1.1.107): desulfurase Uroporphyrinogen-III amino-7-oxononanoate [acyl-carrier-protein] a 1-acyl-sn reductase (EC 34 deaminase (EC dehydrogenase (EC Purine nucleoside (EC 3.5.4.4): dehydrogenase : G1RHH-2304 a (5Z)-3-oxododec- dehydrogenase 3-hydroxyacyl- 4.1.3.27) @ Para- 3-oxoacyl- carrier-protein] 1.2.1.8): Betaine aldehyde isomerase phosphorylase UDP-N-acetyl-α-D- acyl-carrier protein glutamyl-meso-2,6- glucosamine-1,6- L-alanyl-γ-D- amidasedimer (ECwith hydroxyacyl-CoA 3-oxopropanoate phosphorylase (EC 1.1.1.35) / 1-deoxy-D-xylulose Uroporphyrinogen- (EC 2.8.1.7) methyltransferase (EC Phosphoserine 4-methyl-5-(2- 7,8-diaminopelargonate Coα-[α-(5-methoxybenzimidazolyl)]- 1.1.1.100): 3- [+ 4 isozymes] guanosine 1.1.1.205): Inosine- phosphorylase (EC Adenosine deaminase guanine (NADP+) (EC 1.5.1.5) / S-formylglutathione 5-enoyl-[acp] small chain CoA Octaprenyl-diphosphate aminobenzoate HMP-P 3-hydroxyacyl-[acyl-carrier- -glycerol 3- synthase, dehydrogenase (EC (EC 5.3.1.9) Adenosine deaminase (EC 2.4.2.1): muramoyl-L-alanyl- diaminopimeloyl- anhydro-N-acetyl- glutamyl-meso-2,6- pentapeptide 3-oxo-2-(cis-2'-pentenyl)dehydrogenase (EC 3-hydroxybutyryl- Transmembrane 5-phosphate aminotransferase [acyl-carrier- α (EC III methyltransferase : Cysteine phosphooxyethyl)thiazole Coβ-adenosylcobamide 5'-phosphate phosphate oxoacyl-[acyl- 5'-monophosphate uracil (EC 3.5.4.4) CDS Methenyltetrahydrofolate β Carbon monoxide 2-deoxy- - dehydrogenase synthase (EC 2.5.1.-) / [+ 2 isozymes] 7,8- synthase, protein] dehydratase, protein] putrescine (EC 3.5.4.4): Adenosine Purine nucleoside Purine nucleoside γ-D-glutamyl-L-lysyl- D-alanine -D-muramate diaminopimeloyl- stem (meso- -cyclopentane-1-(3- CoA epimerase biotin component BioN biotin reductoisomerase (EC desulfurase 5-aminolevulinate (EC [corrinoid adenosyltranferase]-cob(I)inamide Hydroxymethylpyrimidine thiamine-phosphate 1-acyl-sn-glycerol- 3-oxoacyl-[acyl- carrier protein] glycine betaine Purine nucleoside dehydrogenase (EC phosphorylase: cyclohydrolase (EC 3.5.4.9) S-formylglutathione dehydrogenase D-ribose 1- a purine base (EC 1.1.1.35): 3- Dimethylallyltransferase dihydroneopterin amidotransferase FabA form (EC 4.2.1.59) synthase, deaminase (EC 3.5.4.4) CDS phosphorylase (EC phosphorylase Guanine deaminase D-alanyl-D-alanine D-alanyl-D-alanine diaminopimelate oxobutanoyl)-CoA (EC 5.1.2.3) of energizing (EC 1.1.1.267): 1- [+ 2 isozymes] (EC 2.8.1.7) precorrin-2 Phosphoserine phosphate kinase pyrophosphorylase, adeninyl adenosylcobamide biosynthesis 3-phosphate carrier-protein] reductase phosphorylase (EC Thymidine xanthosine adenosine inosine guanosine : Methylenetetrahydrofolate hydrolase (EC large chain phosphate hydroxyacyl-CoA (EC 2.5.1.1) / 3'-phosphate component Cob(I)alamin : 3-hydroxyacyl- KASII (EC (EC 2.4.2.1): (EC 3.5.4.3); containing) a reduced : Enoyl-CoA deoxy-D-xylulose CDS Porphobilinogen aminotransferase from adenosylcobinamide-GDP synthase, KASII 6-phospho D- 2.4.2.1): Purine nucleoside phosphorylase Purine nucleoside dehydrogenase 3.1.2.12): S- dehydrogenase Geranyltranstransferase (EC 2.6.1.85) D-glyceraldehyde ThiD (EC 2.7.4.7): putative: G1RHH-1917 [acyl-carrier-protein] acyltransferase [+ 3 isozymes] inosine XMP Purine nucleoside Purine nucleoside Purine nucleoside Purine nucleoside + 5-phosphate precorrin-2 Cobalt-precorrin-2 synthase adenosyltransferase (EC dethiobiotin folate polyglutamylation 2.3.1.179): Purine nucleoside Hydroxydechloroatrazine H ferredoxin [iron- CO hydratase (EC 2.6.1.52): pyruvate Coα-[α-(5-methoxybenzimidazolyl) (EC 2.3.1.179): glucono-1,5-lactone phosphorylase (EC (EC 2.4.2.4) CDS phosphorylase formylglutathione 2 (EC ATPase (farnesyldiphosphate : Anthranilate 3-phosphate Hydroxymethylpyrimidine Thiamin-phosphate (EC 2.3.1.51): 1- 3-hydroxyacyl- phosphorylase (EC phosphorylase phosphorylase phosphorylase phosphorylase a 5,10- [isoleucine an S-sulfanyl-[L- C20-methyltransferase (EC 4.2.1.24): 2.5.1.17): Cob(I)alamin β 3-oxoacyl- 3-oxoacyl-[acyl- (EC 2.4.2.1): ethylaminohydrolase hydrolase (EC sulfur] cluster 3-oxo-(7Z)- synthase) (EC 2.5.1.10) synthase, G1RHH-2557 phosphate kinase ]-Co -adenosylcobamide a (2E)-but-2-enoyl-[acp] acyl-sn-glycerol- [acyl-carrier- 6-phosphogluconolactonase Purine nucleoside Purine nucleoside 5-nucleotidase SurE (EC (EC 2.4.2.1): (EC 2.4.2.1): (EC 2.4.2.1): (EC 2.4.2.1): 3-oxo- (11Z)-3-oxo- component MEP Siroheme synthase / cysteine desulfurase] (EC 2.1.1.130): Cobalt- Porphobilinogen adenosyltransferase (EC pyrophosphorylase adenine [acyl-carrier- a 2,3,4-saturated carrier-protein] a (3R)-3-hydroxyacyl- (EC 3.5.99.3): Guanine methenyltetrahydrofolate 7,8- amidotransferase 4-phosphooxy- 1-deoxy-D- a tetrahydrofolate 3-phosphate (EC 3.1.1.31), 3.1.3.5): 5-nucleotidase Purine nucleoside Purine nucleoside Purine nucleoside Purine nucleoside Purine nucleoside hexadecenoyl-CoA biotin BioM of biotin / Geranylgeranyl precorrin-2 C20- synthase (EC 2.5.1.3): protein] fatty acyl-[acp] [acyl-carrier protein]protein] phosphorylase (EC phosphorylase (EC deaminase (EC 3.5.4.3); formate myristoyl-CoA hexadecenoyl-CoA Precorrin-2 oxidase xylulose 5- ATP:Cob(I)alamin HMP-PP synthase, phosphorylase (EC Methylenetetrahydrofolate energizing pyrophosphate synthetase dihydroneopterin L-threonine Thiamin-phosphate Enoyl-[acyl-carrier-protein] 1-acyl-sn-glycerol- dehydratase, eukaryotic type: 6- 2.4.2.1): Purine nucleoside 2.4.2.1): Purine nucleoside SurE (EC 3.1.3.5) CDS phosphorylase (EC phosphorylase (EC phosphorylase (EC phosphorylase (EC 2-C-methyl-D- (EC 1.3.1.76) / methyltransferase Para- (EC 4.2.1.24) phosphate adenosyltransferase (EC Nicotinate-nucleotide-- synthase, Guanine deaminase dehydrogenase module (EC 2.5.1.29): Octaprenyl- Dihydroneopterin 4-hydroxythreonine- pyrophosphorylase biotin Serine reductase [NADH] (EC a (7Z)-3-oxotetradec- 3-phosphate FabA form (EC phosphogluconolactonase phosphorylase (EC phosphorylase (EC 5'-nucleotidase (EC erythritol 4-phosphate Sirohydrochlorin aminobenzoate synthase 2.5.1.17): ATP:Cob(I)alamin dimethylbenzimidazole Dihydrofolate synthase α Purine nucleoside Purine nucleoside Purine nucleoside Purine nucleoside (EC 3.5.4.3): Guanine (NADP+) (EC 1.5.1.5) / diphosphate synthase (EC an S-sulfanyl-[cysteine precorrin-3A porphobilinogen 1.3.1.9): Enoyl-[acyl- 7-enoyl-[acp] 4.2.1.59): 3- (EC 3.1.1.31), F6P uracil 2-deoxy- -D- formate oxidation to CO aldolase (EC 4-phosphate (EC phosphoribosyltransferase (EC 6.3.2.12) @ hydroxymethyltransferase acyltransferase Purine nucleoside 3.1.3.5): G1RHH-2543 phosphorylase phosphorylase phosphorylase phosphorylase Methenyltetrahydrofolate 2 ATPase cytidylyltransferase ferrochelatase synthase, (EC 2.2.1.7) adenosyltransferase (EC carrier-protein] reductase ribose 1-phosphate deaminase (EC 3.5.4.3) CDS desulfurase]-[disordered- 4.1.2.25) / delta dehydrogenase (EC 2.1.2.1): Serine (EC 2.3.1.51): hydroxyacyl-[acyl- D-gluconate phosphorylase (EC guanine (EC 2.4.2.1): (EC 2.4.2.1): (EC 2.4.2.1): (EC 2.4.2.1): component (EC 2.7.7.60) / 2-C- (EC 4.99.1.4) / Octaprenyl diphosphate aminase : 1-deoxy-D- (EC 2.4.2.21): G1RHH-2709 Folylpolyglutamate 3-oxoacyl- Fructose-1,6- cyclohydrolase (EC form scaffold 1-pyrroline-5- Porphobilinogen thiamine phosphate a 10-formyltetrahydrofolate [+ 2 isozymes] G1RHH-1918 carrier-protein] 6-phosphate xanthosine Phosphopentomutase xanthine methyl-D-erythritol Uroporphyrinogen- component (EC (EC 1.1.1.262): 4- adenosylcobinamide synthase (EC 6.3.2.17): hydroxymethyltransferase (EC [acyl-carrier bisphosphatase, 2.4.2.1): Purine nucleoside Purine nucleoside Purine nucleoside Purine nucleoside Purine nucleoside 3.5.4.9): G1RHH-2555 formate biotin BioM of biotin synthase (EC 2.5.1.90) / protein] complex deaminase xylulose 5- a 1,2-diacyl- (EC 5.4.2.7): carboxylate hydroxythreonine- adenine ribotide Dihydrofolate synthase phosphorylase (EC α phosphorylase (EC phosphorylase (EC phosphorylase (EC phosphorylase (EC Formate dehydrogenase energizing 2,4-cyclodiphosphate III methyltransferase Dimethylallyltransferase 2.6.1.85): Para- phosphate Dihydrofolate synthase protein] 3-hydroxyacyl- Phosphogluconate GlpX type Purine nucleoside 2-deoxy- -D-ribose 1-phosphate Methylenetetrahydrofolate synthetase: (EC 2.5.1.61): 4-phosphate ATP:adenosylcobinamide adenosylcobinamide- phosphate a butanoyl-[acp] sn-glycerol Guanine deaminase Phosphopentomutase Xanthine dehydrogenase, synthase (EC (EC 2.1.1.107): aminobenzoate synthase geranyl diphosphate (EC 6.3.2.12) @ reductase [acyl-carrier- dehydratase (EC 3.1.3.11) phosphorylase (EC chain D (EC 1.2.1.2): module (EC 2.5.1.1) / (2E,6E)- precorrin-3B Dihydroneopterin Porphobilinogen phosphotransferase: GDP a 5,10-methylenetetrahydrofolate (EC 6.3.2.12) @ 3-phosphate (EC 3.5.4.3); (EC 5.4.2.7) CDS Phosphopentomutase molybdenum binding dehydrogenase 4.6.1.12): 2-C- Siroheme synthase / synthase, 3-amino-1- biosynthesis (EC 1.1.1.100) protein] (EC 4.2.1.12): : Fructose-1,6- hypoxanthine 2.4.2.1): Purine nucleoside Formate dehydrogenase farnesyl diphosphate deaminase Adenosylcobinamide- Folylpolyglutamate 3-oxoacyl-[acyl-carrier- (EC 5.4.2.7): subunit (EC 1.17.1.4): (NADP+) (EC 1.5.1.5) / Signal methyl-D-erythritol Precorrin-2 oxidase a [cysteine desulfurase]- aldolase (EC hydroxyacetone 1-deoxy-D-xylulose Dihydrofolate synthase : 3-oxoacyl- Phosphatidate dehydratase, Phosphogluconate Hydroxydechloroatrazine phosphorylase (EC 2-deoxy-D-ribose formaldehyde chain D (EC 1.2.1.2) synthase (EC 2.5.1.10) aminase (EC 2.5.1.61) phosphate a tetrahydrofolate synthase (EC 6.3.2.17): protein] synthase, bisphosphatase, Xanthine dehydrogenase, thymine degradation Xanthine dehydrogenase, Methenyltetrahydrofolate his transduction his S-sulfanyl-[disordered- 4.1.2.25) / 1-phosphate 5-phosphate thiamine Cobalamin cytidylyltransferase ethylaminohydrolase 5-phosphate Phosphopentomutase 4-phosphate / Geranylgeranyl IPP (EC 6.3.2.12) @ Dihydrofolate synthase [acyl-carrier FabZ form (EC dehydratase GlpX type (EC molybdenum binding Purine nucleoside α cyclohydrolase (EC 3.5.4.9) oxidation IV (thiol- Formate dehydrogenase: Siroheme synthase / 4-amino-4- synthase KASI (EC 2.3.1.41): 3- (EC 2.7.7.41): Fructose- (EC 3.5.99.3): Guanine (EC 5.4.2.7) CDS -D-ribose-1-phosphate molybdenum binding histidine kinase form scaffold Enoyl-[acyl- (EC 4.2.1.12) independent) 4-(cytidine 5'- pyrophosphate 6-(hydroxymethyl) preuroporphyrinogen adenosyl-cobinamide phosphate Octaprenyl-diphosphate Folylpolyglutamate (EC 6.3.2.12) @ oxoacyl-[acyl-carrier- protein] 4.2.1.59): 3- β subunit (EC 1.17.1.4): phosphorylase (EC thymine : Methylenetetrahydrofolate G1RHH-1814 G1RHH- undecaprenyl- decaprenyl- UDP-N-acetyl- 3-oxo-2-(cis-2'-pentenyl) an N-terminal- N-acetyl-α- Precorrin-2 oxidase protein] complex deoxychorismate Pyridoxine 5'- (EC 2.7.8.26): Phosphatidate -D-fructosebisphosphate 1,6- deaminase (EC 3.5.4.3); Deoxyribose- cob(II)alamin- an apo-["base- (3S,6Z,9Z,12Z,15Z,18Z)-3- an oxidized c- 3-phenyl-2- an L-aspartyl- (S)-3-hydroxy-(11Z) (S)-3-hydroxy-(9Z) diphospho)-2-C- synthetase (EC 2.5.1.29) precorrin-4 -7,8-dihydropterin synthase (EC 2.5.1.-) / synthase (EC 6.3.2.17): protein] synthase, reductase carrier-protein] hydroxyacyl-[acyl- Xanthine dehydrogenase, 2.4.2.1): Purine nucleoside 2-deoxy-D-ribose 5-phosphate Phosphopentomutase urate dehydrogenase 1815 G1RHH-1816 oleate α 2-oxoglutarate O-succinyl-L- L-methionyl-L- a RNA-DNA hybrid (EC 1.3.1.76) / bisphosphatealdolase class Dihydropyrimidine formaldehyde VibB coenzyme A an acyl-[acyl-carrier protein] a malonyl-[acp] hydroxytetracosapentaenoyl-CoA O-succinyl-L-homoserine diphospho-N- diphospho-N- UDP-N-acetyl- -D-muramoyl- di-trans,octa-cis methanethiol a malonyl-[acp] -cyclopentane-1-(3R- (S)-lactate tyr D-muramoyl- Asn -octadecenoyl-CoA -octadecenoyl-CoA methyl-D-erythritol Cysteine Aminodeoxychorismate Uroporphyrinogen- phosphate G1RHH-2708 Dihydrofolate synthase a 10-formyltetrahydrofolate cytidylyltransferase reductase carrier-protein] KDGP Guanine deaminase phosphate CO ATP [CblC-CblD off/His-on" homoserine type cytochrome oxopropanoate [tRNA ] : Octaprenyl diphosphate 2-amino-4-hydroxy-6- 5,6-dimethylbenzimidazole Adenosylcobinamide- Dimethylallyltransferase [+ 3 isozymes] molybdenum binding phosphorylase (EC (EC 5.4.2.7): 2 α γ alanyl-[protein] predicted Sirohydrochlorin Cobalt-precorrin-4 synthase 3-oxoacyl-[acyl-carrier- (EC a 2,3,4-saturated a trans-2-enoyl- I (EC 4.1.2.13) dehydrogenase a 10- Aldehyde 4'-phosphopantetheinyl 3-oxoacyl-[acyl-carrier- 3-hydroxyacyl-CoA O-acetylhomoserine Long-chain-fatty-acid-- acetylmuramoyl- UDP-N-acetyl- acetylmuramoyl- -D-glucosamine L-alanyl- -D- -undecaprenyl 2-oxoglutarate O-acetylhomoserine 3-oxoacyl-[acyl-carrier- hydroxyoctanoyl)-CoA L-lactate L-alanine(1-) Ribonuclease Enoyl-CoA 4-diphosphocytidyl- desulfurase lyase (EC III synthase (EC 2.5.1.1) / (EC 6.3.2.12) @ a (3R,7Z)-3- [NADH] (EC 4-hydroxy-2-oxoglutarate (EC 3.5.4.3): Guanine aldolase complex] B12-enzyme] Enoyl-CoA Histidinol- Methionine N-acetylmuramoyl- Aspartyl-tRNA(Asn) ABC synthase (EC hydroxymethyldihydropteridine phosphate thiamine diphosphate Coα-[α-(adenin-9-yl)]- : Fructose- DHAP [NADP+] (EC 1.3.1.2) Phosphopentomutase formyltetrahydrofolate dehydrogenase Cob(I)alamin protein] synthase, dehydrogenase (EC sulfhydrylase (EC 2.5.1.49) CoA ligase (EC 6.2.1.3) L-alanyl-γ-D- α-D-glucosamine pentapeptide UDP-N- glutamyl-L-lysyl- phosphate dehydrogenase protein] synthase, HII (EC 3.1.26.4) his ferrochelatase (EC 2.8.1.7) C11-methyltransferase 4.1.3.38) # PabAc: (EC 4.2.1.75): (EC 2.6.99.2) Nicotinate-nucleotide-- protein] synthase, fatty acyl-[acp] 1.3.1.9): Enoyl- [acyl-carrier protein] deaminase (EC 3.5.4.3) CDS (EC 4.1.2.4): Deoxyribose-phosphate transferase entD Phospho-N- sulfhydrylase hydratase [isoleucine dehydrogenase phosphate aminopeptidase L-alanine amidotransferase hydratase his transporter 2-C-methyl-D- pyrophosphokinase (EC guanylyltransferase Geranyltranstransferase Coβ-adenosylcobamide hydroxytetradec- Phosphatidate aldolase (EC 4.1.3.16) Triosephosphate : Dihydropyrimidine (EC 5.4.2.7) CDS adenosyltransferase 1.1.1.35): 3-hydroxyacyl- : Long-chain-fatty- glutamyl-L- UDP-N- acetylglucosamine- D-alanyl-D-alanine E1 component : Ribonuclease (EC 4.99.1.4) / geranyl , SufS (EC 2.1.1.133): Cobalt- Aminodeoxychorismate Uroporphyrinogen- : Pyridoxine a 5,10-methylenetetrahydrofolate KASII (EC 2.3.1.179): bisphosphate Deoxyribose- aldolase (EC 4.1.2.4) Formyltetrahydrofolate (EC 1.2.1.3) (EC 2.7.8.-); Holo- KASI (EC 2.3.1.41): 3- / O-succinylhomoserine acetylmuramoyl- (EC 2.5.1.49) / O- KASI (EC 2.3.1.41): 3- (EC 1.1.2.3) (EC 3.4.11.18) amidase (EC subunit: Aspartyl- [isoleucine erythritol kinase 2.7.6.3): 2-amino-4-hydroxy-6- dimethylbenzimidazole (farnesyldiphosphate 7-enoyl-[acp] cytidylyltransferase [acyl-carrier- @ 2-dehydro-3- degradation] aminotransferase of L-histidine Uroporphyrinogen- (EC 2.7.7.62): 5'-phosphate 3-oxoacyl-[acyl-carrier- aldolase isomerase dehydrogenase : Aldehyde (EC 2.5.1.17): [acyl-carrier protein] oxoacyl-[acyl-carrier- CoA dehydrogenase (EC sulfhydrylase (EC acid--CoA ligase (EC lysyl- D-alanine acetylglucosamine- -N-acetylmuramyl- (EC 1.2.4.2): 2- succinylhomoserine oxoacyl-[acyl-carrier- : L-lactate HII (EC (EC 2.7.1.148): 4- diphosphate subfamily: precorrin-4 C11- lyase (EC 4.1.3.38) # III synthase (EC 5'-phosphate phosphoribosyltransferase (EC 2.7.7.41): protein] reductase phosphate : Deoxyribose- D-ribose 5-phosphate Aldehyde Degradation deformylase (EC pentapeptide- (EC 4.2.1.17) / 3- (EC 2.6.1.9) : Methionine 3.5.1.28): N- tRNA(Asn) degradation] (7,8-dihydropterin- Adenosylcobinamide- synthase) (EC 2.5.1.10) 3-hydroxyacyl- deoxyphosphogluconate class I (EC (EC 5.3.1.1): pseudouridine UTP and CTP dephosphorylation I [NADP+] dehydrogenase Cob(I)alamin -N-acetylmuramyl- (pentapeptide) oxoglutarate 3.1.26.4) CDS III methyltransferase Cysteine methyltransferase synthase (EC benzimidazolyl adenosylcobamide protein] synthase, xanthine aldolase (EC phosphate aldolase (EC 3.5.1.10): G1RHH-2556 synthase, alternative (EC protein] synthase, Enoyl-CoA hydratase 2.5.1.48): G1RHH-2713 Long-chain-fatty-acid-- transferase sulfhydrylase protein] synthase, dehydrogenase @ Aromatic- aminopeptidase acetylmuramoyl- amidotransferase (EC 4.2.1.17) / 3- diphosphocytidyl- 6-yl)methyl (EC 2.4.2.21): G1RHH-2709 phosphate / Geranylgeranyl [acyl-carrier- Phosphatidate [+ 2 isozymes] aldolase (EC degradation hydroxyacyl-CoA predicted (EC 2.1.1.107): Octaprenyl-diphosphate 4-aminobenzoate uroporphyrinogen-III Triosephosphate (EC 1.2.1.3) CDS adenosyltransferase 2.7.8.7): G1RHH-1017 [isoleucine degradation] CoA ligase (EC 6.2.1.3) (pentapeptide) pyrophosphoryl- (EC 2.7.8.13) dehydrogenase (EC 2.5.1.48): (EC 1.1.2.3) CDS L-alanine Ribonuclease Aspartyl-tRNA(Asn) hydroxyacyl-CoA 2-C-methyl- desulfurase diphosphate pyrophosphate synthetase biosynthesis from adenosylcobinamide-GDP protein] cytidylyltransferase 4.1.2.14): 4-hydroxy-2- UTP Dihydropyrimidine methylglyoxal degradation I [+ 2 isozymes] 3-oxoacyl-[acyl-carrier- O-acetylhomoserine 3-oxoacyl-[acyl-carrier- dehydrogenase amino-acid (EC 3.4.11.18) ABC Siroheme synthase / synthase (EC 2.5.1.-) / precorrin-5 α a 3-oxohexanoyl-[acp] fatty acid isomerase Xanthine dehydrogenase, (EC : Long-chain-fatty- pyrophosphoryl- undecaprenol N- E1 component G1RHH-2713 D-erythritol (EC 2.8.1.7) -ribazole 5'-phosphate adenosylcobinamide-GDP Coα-[α-(adenin-7-yl)]- (EC D-glyceraldehyde dehydrogenase [+ 5 isozymes] Holo-[acyl-carrier protein] protein] synthase, (EC 4.2.1.17) / 3- sulfhydrylase (EC 2.5.1.49) : Phospho-N- protein] synthase, (EC 1.1.1.35) / 3- aminotransferase amidase (EC HI (EC 3.1.26.4) amidotransferase dehydrogenase his his Dimethylallyltransferase Uroporphyrinogen pyridoxine 5'-phosphate (EC 2.5.1.29): Octaprenyl- dehydratase, biosynthesis initiation I oxoglutarate aldolase (EC (EC 5.3.1.1) pseudouridine molybdenum binding acetaldehyde acetaldehyde D-glyceraldehyde 3-phosphate undecaprenol N- acetylglucosamine L-lactate Methionine transporter Precorrin-2 oxidase benzimidazole Enoyl-[acyl- 3-phosphate [NADP+] (EC 1.3.1.2) formate formate ATP:Cob(I)alamin hydroxyacyl-CoA acid--CoA ligase (EC acetylmuramoyl- Dihydrolipoamide : Ribonuclease (EC 1.1.1.35) / 2-phospho-4-(cytidine , SufS Dihydropteroate III decarboxylase diphosphate synthase (EC Coβ-adenosylcobamide FabA form CTP synthase synthase (EC 2.7.8.7) KASII (EC 2.3.1.179): / O-succinylhomoserine undecaprenyl- O-acetylhomoserine KASII (EC 2.3.1.179): hydroxybutyryl-CoA dehydrogenase (EC 2.6.1.57) aminopeptidase N-acetylmuramoyl- of L-histidine (EC 2.5.1.1) / 3-oxoacyl-[acyl-carrier a CDP- subunit (EC 1.17.1.4): methylglyoxal acetylglucosamine transferase (EC Aspartyl-tRNA(Asn) 3-hydroxybutyryl- 5'-diphospho)-2-C- carrier-protein] (EC 6.3.4.2): : Dihydropyrimidine adenosyltransferase : Holo-[acyl-carrier 3-oxoacyl-[acyl-carrier- dehydrogenase (EC sulfhydrylase (EC 2.5.1.48) pentapeptide- dehydrogenase 3-oxoacyl-[acyl-carrier- epimerase (EC (EC 1.1.2.3) : Histidinol- HI (EC Geranyltranstransferase Cysteine synthase (EC 4.1.1.37): Pyridoxamine protein] reductase (EC (EC 4.2.1.59): diacylglycerol acetyl-CoA Xanthine dehydrogenase, Lactoylglutathione diphosphate AMP oleoyl-CoA transferase (EC 2.4.1.227): UDP-N- diphospho-N- sulfhydrylase (EC 3.4.11.18) L-alanine amidotransferase methyl-D-erythritol sirohydrochlorin Cobalamin synthase (EC Octaprenyl diphosphate Nicotinate-nucleotide-- reductase dehydrogenase (EC 2.5.1.17): protein] synthase (EC protein] synthase, 1.1.1.35) / 3-hydroxybutyryl- : O-acetylhomoserine (EC 1.8.1.4): protein] synthase, 5.1.2.3): Enoyl-CoA phosphate 3.1.26.4) CDS CoA epimerase (farnesyldiphosphate desulfurase (EC 2.5.1.15): Uroporphyrinogen 1.1.1.100): G1RHH-1018 3-hydroxyacyl- acetyl-CoA pseudouridine molybdenum binding G1RHH-2687 UMP lyase (EC 4.4.1.5): 2.4.1.227): UDP-N- acetylglucosamine- acetylmuramoyl- (EC 2.5.1.49) / O- : L-lactate : Methionine amidase (EC subunit B (EC Histidine ABC 5'-phosphate 2.7.8.26): G1RHH-2708 synthase (EC 2.5.1.90) / dimethylbenzimidazole Putative [NADH] (EC D-glyceraldehyde [NADP+] ATP:Cob(I)alamin CoA epimerase (EC UMP Dihydrolipoamide aminotransferase a nucleoside 5'- (EC 5.1.2.3) 2-C-methyl-D- (EC 2.8.1.7) precorrin-6A Dihydropteroate III decarboxylase (EC [acyl-carrier- carboxyltransferase: 5'-phosphate 3',5'-ADP a holo-[VibB aryl-carrier protein] acyl-carrier protein a 3-oxoacyl-[acp] sulfhydrylase (EC L-alanyl-γ-D- succinylhomoserine a 3-oxodocosanoyl-[acp] hydratase [isoleucine dehydrogenase aminopeptidase 3.5.1.28): N- DNA his transporter, his Sirohydrochlorin synthase) (EC 2.5.1.10) oxidase phosphoribosyltransferase [+ 3 isozymes] phosphatidylglycerophosphate Lactoylglutathione ditrans,octacisacetylglucosamine-- decaprenyl--N-acetylmuramyl- monophosphate 6.3.5.6) @ : Enoyl-CoA Dimethylallyltransferase 1.3.1.9): Enoyl- 3-phosphate 5,6-dihydrothymine adenosyltransferase 5.1.2.3): Enoyl-CoA dehydrogenase (EC (EC erythritol 4-phosphate cobaltochelatase : Cysteine synthase protein] Acetyl-coenzyme A urate CTP 5-nucleotidase acetyl-CoA acetyl-CoA pyrimidine deoxyribonucleotides lyase (EC succinate L-homocysteine undecaprenyldiphospho--N-acetylmuramyl- pyrophosphoryl-(N glutamyl-L-lysyl- sulfhydrylase (EC 1.1.2.3) CDS (EC 3.4.11.18) acetylmuramoyl- Glutamyl-tRNA(Gln) ATP-binding / Geranylgeranyl (EC 1.4.3.5): (EC 2.5.1.1) / (2E,6E)- (EC 2.4.2.21): G1RHH-2709 synthase: Putative [acyl-carrier- a [cobalamin (EC a holo-["base- hydratase [isoleucine 3-hydroxyacyl-CoA hydratase cytidylyltransferase desulfurase Cobalt-precorrin-6x (EC 2.5.1.15) coproporphyrinogen III adenosylcobalamin 5'-phosphate carboxyl transferase NAD-dependent Ribosomal SurE (EC D-alanyl-D-alanine NADH CO succinyl-CoA (EC 2.5.1.48): O- a reduced c- [+ 2 isozymes] an N-terminal L- L-alanine (EC 4.99.1.3): pyrophosphate synthetase Pyridoxamine a (3R)-3-hydroxyhexanoyl-[acp] phosphatidylglycerophosphate Hydantoinase/ dephosphorylation 4.4.1.5) CDS a [cyanocobalamin (6Z,9Z,12Z,15Z,18Z)-3- N-acetyl-(N- UDP -acetylglucosamine) 2 dehydrogenase pyruvate 3-(4- met amidotransferase reductase (EC 1.3.1.54) farnesyl diphosphate benzimidazole 3-hydroxyacyl- protein] reductase large subunit 3.1.3.5): 5- trafficking triphosphate off/His-on" UDP type cytochrome alanyl-[protein] [isoleucine (EC 2.7.7.60) / 2-C- (EC 2.8.1.7) adenosylcobinamide- malonyl-CoA glyceraldehyde- acetylhomoserine amidase (EC Sirohydrochlorin (EC 2.5.1.29): Octaprenyl- Coproporphyrinogen 5'-phosphate oxoprolinase Nucleoside triphosphate [+ 2 isozymes] reductase CblC] oxotetracosapentaenoyl-CoA acetylglucosaminyl) -N-acetylmuramyl- (EC 1.1.1.35): 3- phe hydroxyphenyl) subunit B (EC : Cobalt-precorrin- synthase (EC 2.5.1.10) ribotide phosphate [acyl-carrier- CDP-diacylglycerol-- [+ 2 isozymes] 3-phosphate pseudouridine nucleotidase (R)-S- protein CblD] B12-enzyme] sulfhydrylase (EC N-acetyl-D- Ribose ABC methyl-D-erythritol cobaltochelatase diphosphate synthase (EC CDS 7,8- oxidase (EC GDP 3-hydroxyacyl-[acyl-carrier- family protein: pyrophosphohydrolase muramoyl-L-alanyl-γ-D- (pentapeptide) hydroxyacyl-CoA pyruvate ala 6.3.5.7): Aspartyl- 3-hydroxyacyl- an S-sulfanyl-[cysteine 6x reductase (EC III oxidase, aerobic / Geranylgeranyl protein] glycerol-3-phosphate 3- Malonyl CoA-acyl synthase E CMP SurE (EC lactoylglutathione muramate transport 2,4-cyclodiphosphate (EC dihydropteroate protein] dehydratase, dehydrogenase Hydantoinase/ glutamyl-L-lysyl-D-alanine dehydrogenase (EC tRNA(Asn) CoA D-ribose D-ribose (EC 1.3.3.3): pyrophosphate dehydratase, phosphatidyltransferase carrier protein (EC 4.2.1.70) adenosine S-methyl-5'-thioadenosine MazG (EC 3.6.1.8): succinate met 3-oxo-2-(cis-2'-pentenyl) system, synthase (EC Octaprenyl diphosphate desulfurase]-S- Pyridoxamine Cobalamin FabZ form (EC 4.2.1.59) (EC 1.2.1.12): 5-nucleotidase 3.1.3.5) CDS oxoprolinase SAM-dependent amidotransferase dehydrogenase precorrin-6B Dihydrofolate Coproporphyrinogen synthetase (EC 2.5.1.29) FabZ form (EC 2.7.8.5): CDP- transacylase (EC : Ribosomal nucleotides degradation II Nucleoside triphosphate Polymeric Compound Degradation -cyclopentane-1-(3- permease 4.6.1.12): 2-C- cobalt-sirohydrochlorin synthase (EC 2.5.1.90) / sulfanyl-[disordered- 5'-phosphate adenosylcobalamin synthase : 3-hydroxyacyl- NAD-dependent SurE (EC 5'-nucleotidase family protein dCTP dCMP methyltransferase an L-asparaginyl- (EC 1.1.1.35): 3- synthase (EC III oxidase, aerobic : Octaprenyl diphosphate (EC 4.2.1.59): diacylglycerol-- 2.3.1.39): Malonyl CoA- large subunit degradation III oxooctanoyl)-CoA methyl-D-erythritol Dimethylallyltransferase form scaffold precorrin-6B (C 15 ) oxidase (EC 2.7.8.26): 5-methoxy-6-methylbenzimidazolyl adenosylcobamide gondoate biosynthesis (anaerobic) glyceraldehyde- (EC 3.1.3.5): S-methyl-5'- [tRNA Asn ] 6.3.2.12) @ NAD [acyl-carrier-protein] 3.1.3.5): 5- Dihydropyrimidinase 2, in cluster with hydroxyacyl-CoA (EC 2.5.1.1) / (2E,6E)- protein] complex (EC 1.4.3.5): synthase (EC 3-hydroxyacyl- glycerol-3-phosphate acyl carrier protein 3-phosphate pseudouridine alginate degradation predicted 4-phosphate methyltransferase: protoporphyrinogen IX phosphorylation and geranyl G1RHH-2708 biosynthesis from adenosylcobinamide-GDP nucleotidase G1RHH-2543 thioadenosine Hydroxyacylglutathione dehydrogenase Folylpolyglutamate Pyridoxamine folate transformations I 3-hydroxyacyl-[acyl-carrier- [acyl-carrier- 1-(3-sn- AMP 5'-methylthioadenosine (EC 3.5.2.2): Deoxyuridine chitin degradation II (Vibrio) farnesyl diphosphate Cobalt-precorrin-6y [+ 6 isozymes] 2+ ABC 2+ transhydrogenation [+ 3 isozymes] SurE (EC hydrolase (EC 3.1.2.6) (EC Mn Mn 2-C-methyl-D-erythritol- synthase 5'-phosphate diphosphate Coα-[α- protein] dehydratase, protein] a malonyl-[acp] an oleoyl-[acp] a malonyl-[acp] AMP nucleosidase uridine phosphorylase Dihydropyrimidinase 5'-triphosphate transporter synthase (EC 2.5.1.10) C5-methyltransferase 5-methoxy-6-methylbenzimidazole phosphatidyl) 3.1.3.5) CDS : SAM-dependent alginate 3-oxo-(11Z)- 3-oxo-(9Z)- 2,4-cyclodiphosphate cobalt-factor III (EC 6.3.2.17): NAD + FabA form (EC 4.2.1.59) uracil (EC 2.4.2.28): 5'- (EC 3.5.2.2) CDS nucleotidohydrolase (EC / Geranylgeranyl oxidase (EC (benzimidazolyl)]-Co -sn-glycerol 3-oxoacyl-[acyl- 13-DPG (EC 3.2.2.4): AMP chitin octadecenoyl-CoA octadecenoyl-CoA of Mn2+ a [cysteine Dihydrofolate a tetrahydrofolate a (2E,7Z)-tetradeca- 5'-nucleotidase methylthioadenosine methyltransferase 2, in 1-hydroxy-2- pyrophosphate precorrin-7 NAD kinase β-adenosylcobamide Nicotinate-nucleotide-- : 3-hydroxyacyl- 3-phosphate carrier-protein] 3-oxoacyl-[acyl-carrier- nucleosidase 3-(carbamoylamino)- 3.6.1.23): Deoxyuridine desulfurase]-(S- synthase (EC (EC 2.7.1.23): [acyl-carrier-protein] 2,7-dienoyl-[acp] protein] synthase, (EC 3.1.3.5): phosphorylase (EC 5'-triphosphate Hydroxyacylglutathione methyl-2-(E) synthetase (EC 2.5.1.29) protoporphyrin IX PLP 5'-phosphate dimethylbenzimidazole Phosphatidylglycerophosphatase synthase, KASI Phosphoglycerate (EC 3.2.2.4) CDS 2-methylpropanoate Chloride sulfanyl) -[disordered- 5 6.3.2.12) @ Alginate 2 precorrin-7 (C ) NAD kinase (EC KASIII (EC 2.3.1.180): G1RHH-2543 5-MTR-1-P hydrolase (EC 3.1.2.6): -butenyl 4- : Octaprenyl diphosphate Formyltetrahydrofolate phosphoribosyltransferase Enoyl-[acyl- A (EC 3.1.3.27): (EC 2.3.1.41): 3- kinase (EC 2.7.2.3) adenine Nucleoside triphosphate lyase an N-terminal- an N-terminal- chloride channel chloride form scaffold methyltransferase: a (2E)-hex-2-enoyl-[acp] Beta- α a single (3S,6Z,9Z,12Z,15Z,18Z,21Z)-3- undecaprenyl- 1-myristoyl- 1-palmitoyl- 3-oxo-2-(cis-2'-pentenyl) (S)-3-hydroxy-(9Z) synthase (EC 7,8-dihydrofolate Ferrochelatase, 2.7.1.23) CDS deformylase (EC (EC 2.4.2.21): G1RHH-2709 carrier- Phosphatidylglycerophosphatase oxoacyl-[acyl-carrier- 3-oxoacyl-[acyl-carrier- pyrophosphohydrolase Hydroxyacylglutathione 4-deoxy- -L- isovalerate 3-methoxy-4-hydroxyphenylglycol a peptidoglycan a lipid II an alkylated DNA a (3R,7Z)-3-hydroxy- an L-glutamyl- a myo-inositol diphosphate + : Phosphoglycerate cytidine ureidopropionase precursor a (5Z)-tetradec-5-enoyl-[acp] a malonyl-[acp] an apo [peptidyl-carrier protein] coenzyme A diphospho-N- cob(II)yrinate a myristoyl-[acp] sn-glycerol a palmitoleoyl-[acp] sn-glycerol -cyclopentane-1-(3R- L-methionyl-L- L-methionyl- protein cobalt-precorrin-3 protein] complex Cobalt-precorrin-6y NADP protein] synthase, hydrolase (EC erythro-hex-4- a chitodextrin stranded DNA hydroxytetracosahexaenoyl-CoA ATP a purine ribonucleoside arsenate GTP Gln -hexadecenoyl-CoA monophosphate synthase monoglutamate protoheme 3.5.1.10): G1RHH-2556 α α protein] A (EC protein] synthase, kinase (EC MazG (EC 3.6.1.8): hexadec-7-enoyl-[acp] [tRNA ] Co -[ - 5-methoxy-6-methylbenzimidazole Enoyl-[acyl-carrier-protein] an L-1- (EC 3.5.1.6): Beta- (EC 4.2.2.3) 3-oxoacyl-[acyl-carrier- Holo-[acyl-carrier protein] Exodeoxyribonuclease 3-hydroxyacyl-CoA Acetyl-coenzyme A Alcohol dehydrogenase, acetylmuramoyl- UDP-N-acetyl- a,c-diamide 3-phosphate 3-phosphate Cell division hydroxyhexanoyl)-CoA DNA-3- 3-hydroxyacyl-[acyl- valyl-[protein] glycyl-[protein] Enoyl-CoA (2E,6E)-farnesyl C5-methyltransferase ferro-lyase Glycine adenosylcobinamide-GDP reductase Nucleoside triphosphate enopyranuronate- Purine nucleoside 1-acyl-sn-glycerol- 1-acyl-sn-glycerol- Enoyl-CoA Methionine Methionine Aspartyl-tRNA(Asn) (EC 1.17.7.1) NAD(P) [+ 2 isozymes] (benzimidazolyl)]-Co ribotide phosphate 3-oxoacyl-[acyl- 3-oxoacyl-[acyl-carrier- 2.7.2.3) CDS ureidopropionase (R)-lactate : G1RHH- VII large subunit dehydrogenase (EC synthetase (EC 6.2.1.1) zinc containing (EC L-alanyl-γ-D- α-D-glucosamine ATP:Cob(I)alamin protein FtsI methyladenine Guanylate cyclase- diphosphate adenosylcobinamide-GDP biosynthesis cleavage reductase [NADH] (EC [NADH] (EC phosphatidyl- dUTP dUMP α-L-guluronate protein] synthase, synthase (EC 2.7.8.7) 3-phosphate 3-phosphate carrier-protein] aminopeptidase aminopeptidase amidotransferase hydratase Arginine/ arg : 1-hydroxy- (EC 4.99.1.1): transhydrogenase: β-adenosylcobamide carrier-protein] protein] synthase, (EC 3.5.1.6) CDS 2569 (EC 3.1.11.6): 1.1.1.35): 3-hydroxyacyl- : Acetyl-coenzyme A 1.1.1.1): Alcohol glutamyl-L-lysyl- UDP-N- adenosyltransferase phosphorylase [Peptidoglycan hydratase [isoleucine glycosylase: related protein: arg precorrin-8x ubiquinol-8 biosynthesis 1.3.1.9): Enoyl-[acyl- sn-glycerol KASI (EC 2.3.1.41): 3- : Holo-[acyl-carrier acyltransferase acyltransferase dehydratase, FabA (EC 3.4.11.18) (EC 3.4.11.18) subunit: Aspartyl- [isoleucine ornithine 2-methyl-2- a [cysteine desulfurase]- Ferrochelatase, from cobyrinate a,c-diamide system H 1.3.1.9): Enoyl- synthase, KASII KASIII (EC 2.3.1.180): 3-phospho-D-glycerate (EC 2.4.2.1): degradation] (prokaryotic) G1RHH-1796 Cobalamin synthase (EC carrier-protein] reductase 4-deoxy-α-L- oxoacyl-[acyl-carrier- protein] synthase (EC Exodeoxyribonuclease CoA dehydrogenase (EC synthetase (EC 6.2.1.1) dehydrogenase, D-alanyl-D-alanine acetylglucosamine- (EC 2.5.1.17): (EC 2.3.1.51): 1- (EC 2.3.1.51): 1- synthetase] G1RHH-2637 form (EC 4.2.1.59) G1RHH-2623 degradation] antiporter Undecaprenyl [scaffold protein- Cobalt-precorrin- protoheme protein: Methylenetetrahydrofolate [acyl-carrier- (R)-3-amino-2- a chitodextrin Purine nucleoside (EC 4.2.1.17) / 3- : Methionine : Methionine tRNA(Asn) (E)-butenyl cobalt-precorrin-4 Octaprenyl-diphosphate a 7,8-dihydrofolate G1RHH-1797 a 10- phosphatidylglycerol (EC 2.3.1.179): 3- 3-oxoacyl-[acyl-carrier- protein] synthase, VII large subunit (EC Acetyl-coenzyme A zinc containing (EC -N-acetylmuramyl- ATP:Cob(I)alamin (EC 2.4.1.129) ornithine ornithine all-trans- cob(II)yrinate a,c-diamide Glycine 2.7.8.26): G1RHH-2708 [+ 2 isozymes] protein] 2,3-bisphosphoglycerate- 2,3-bisphosphoglycerate- methylpropanoate 5-hydroxy-CTP 5-hydroxy-CMP erythro-hex-4- 4'-phosphopantetheinyl Enoyl-CoA hydratase acyl-sn-glycerol- acyl-sn-glycerol- hydroxyacyl-CoA DNA-3- : 3-hydroxyacyl- aminopeptidase aminopeptidase Adenylate cyclase (EC amidotransferase (EC 4.2.1.17) / 3- ArcD (E)-4-hydroxy-3- diphosphate synthase (EC 2.5.1.-) / (2Fe-2S)] complex 8x methylmutase ferro-lyase (EC dehydrogenase formyltetrahydrofolate biosynthesis II (non-plastidic) oxoacyl-[acyl-carrier- protein] synthase, (pentapeptide) adenosyltransferase phosphorylase (EC : Cell division enopyranuronate- Exodeoxyribonuclease [isoleucine degradation] synthetase (EC 6.2.1.1) Alcohol dehydrogenase 3-phosphate 3-phosphate methyladenine [acyl-carrier-protein] (EC 3.4.11.18) (EC 3.4.11.18) 4.6.1.1) / Guanylate Aspartyl-tRNA(Asn) hydroxyacyl-CoA Possible methylbut-2-en- Cobalt- synthase Dimethylallyltransferase (EC 5.4.1.2): 4-hydroxybenzoate octaprenyl Cob(I)alamin NADPH cleavage (NADP+) (EC 1.5.1.5) / thiamine diphosphate reductase protein] synthase, independent independent pyruvate 3-oxoacyl-[acyl-carrier- transferase entD dehydrogenase tetrahydrofolate salvage from Coα-[α-(5-methoxy-6-methylbenzimidazolyl) a hexanoyl-[acp] β-D-mannuronate : Acetyl-coenzyme A (EC 1.1.1.1): Alcohol pyrophosphoryl- (EC Purine nucleoside protein FtsI cyclase (EC 4.6.1.2): dehydrogenase fucose fucose ABC fucose precorrin-4 C11- (EC 2.5.1.31): Cobalt-precorrin-8x 4-hydroxybenzoatediphosphate protoheme adenosyltransferase system Methenyltetrahydrofolate biosynthesis II (Bacillus) an acetoacetyl-[acp] phosphoglycerate phosphoglycerate protein] synthase, (EC 2.7.8.-); Holo- VII small subunit (EC 4.2.1.17) / 3- 1-acyl-sn-glycerol- 1-acyl-sn-glycerol- (EC 1.1.1.35) / 3- glycosylase II 3-hydroxyacyl-[acyl- amidotransferase 1-yl diphosphate (EC 2.5.1.1) / Methylenetetrahydrofolate 5,10-methenyltetrahydrofolate β [+ 2 isozymes] DHAP an (11Z)-3-oxo-icos-11-enoyl-[acp] synthetase (EC 6.2.1.1) undecaprenol N- phosphorylase [Peptidoglycan Methionine Methionine (EC 2.5.1.17): H protein ]-Co -adenosylcobamide 5'-phosphate mutase (EC mutase (EC KASII (EC 2.3.1.179): [acyl-carrier protein] (EC 3.1.11.6): hydroxyacyl-CoA dehydrogenase Cob(I)alamin 3-phosphate 3-phosphate hydroxybutyryl-CoA (EC 3.2.2.21) Adenylate cyclase (EC (EC 1.1.1.35) / transporter, methyltransferase Undecaprenyl Geranyltranstransferase a [co-chaperone]- methylmutase (EC flavin biosynthesis I (bacteria and plants) polyprenyltransferase cyclohydrolase (EC 2-(2-carboxy-4- Glycerol-3- acetylglucosamine (EC 2.4.2.1): carrier-protein] aminopeptidase aminopeptidase Aspartyl-tRNA(Asn) dehydrogenase a 5,10- 3-oxoacyl-[acyl-carrier- a (7Z)-tetradec- Exodeoxyribonuclease dehydrogenase (EC (EC 1.1.1.1) CDS adenosyltransferase [+ 2 isozymes] : DNA-3- 4.6.1.1) / Guanylate 3-hydroxybutyryl- (EC 2.1.1.133) diphosphate a tetrahydrofolate (EC 2.5.1.39): 4- Cob(I)alamin CDS 3.5.4.9): G1RHH-2555 methylthiazol-5- 5.4.2.1): 2,3- 5.4.2.1): 2,3- Beta- 3-oxoacyl-[acyl-carrier- synthase, alternative (EC acyltransferase acyltransferase di-trans,octa-cis epimerase (EC dehydratase, FabZ (EC 3.4.11.18) (EC 3.4.11.18) 4-hydroxy- 4-hydroxy- (farnesyldiphosphate [scaffold protein- (NADP+) (EC 1.5.1.5) / protein] synthase, 7-enoyl-[acp] phosphate 3-oxoacyl-[acyl- Amino Acid Degradation isovaleryl-CoA AMP diphosphate 3-methoxy-4- transferase (EC Purine nucleoside cyclic-GMP amidotransferase CoA epimerase synthase (EC hydrogenobyrinate hydroxybenzoate adenosyltransferase methenyltetrahydrofolate yl)ethyl phosphate bisphosphoglycerate- bisphosphoglycerate- protein] synthase, 2.7.8.7): G1RHH-1017 VII small subunit (EC 1.1.1.35) / 3-hydroxybutyryl- (EC 2.5.1.17): (EC 2.3.1.51): (EC 2.3.1.51): 5.1.2.3): Enoyl-CoA methyladenine form (EC 4.2.1.59) 3-methylbut- 3-methylbut- : Cobalt- synthase) (EC 2.5.1.10) (2Fe-2S)] complex Methylenetetrahydrofolate Methenyltetrahydrofolate Methylenetetrahydrofolate thiamine-phosphate dehydrogenase carrier protein] α hexosaminidase hydroxyphenylglycolaldehyde 2.4.1.227): UDP-N- phosphorylase (EC -undecaprenyl a peptidoglycan : Methionine : Methionine subunit B (EC Putative KASI (EC 2.3.1.41): 3- independent independent a 4-deoxy- -L- a single-stranded a ribonucleoside CoA epimerase (EC Cob(I)alamin G1RHH-1918 glycosylase (EC 5.1.2.3) 2-enyl 2-enyl precorrin-4 C11- / Geranylgeranyl GTP polyprenyltransferase (EC pyrophosphorylase, 3-oxoacyl- reductase (EC (EC 3.2.1.52): acyl-carrier protein a (7Z)-3-oxo-hexadec-7-enoyl-[acp] a holo [peptidyl-carrier protein] 3',5'-ADP acetylglucosamine- 1,2-dimyristoyl- G1RHH-1918 diphosphate hydratase [isoleucine : 3-hydroxyacyl- aminopeptidase aminopeptidase myo-inositol permease Cobyrinic acid A,C- 3-octaprenyl-4- dehydrogenase cyclohydrolase (EC dehydrogenase Coα-[α-(5-methoxy-6-methyl- oxoacyl-[acyl-carrier- [NAD(P)+] (EC erythro-hex-4- oligodeoxyribonucleotide 5'-monophosphate 5.1.2.3): Enoyl-CoA ditrans,octacis- adenosyltransferase ribose-1-arsenate a purine base 1-palmitoyl-2- II (EC 6.3.5.6) @ : Enoyl-CoA methyltransferase di-trans,octa-cis putative: G1RHH-1917 [acyl-carrier- L-valine degradation I G1RHH-2604 [acyl-carrier-protein] (EC 3.4.11.18) (EC 3.4.11.18) a purine often a purine diphosphate diphosphate pyrophosphate synthetase diamide synthase: hydroxybenzoate ATP:Cob(I)alamin (NADP+) (EC 1.5.1.5) / 3.5.4.9): G1RHH-2555 (NADP+) (EC 1.5.1.5) / benzimidazolyl)]-Coβ-adenosylcobamide protein] synthase, 1.1.1.94): Glycerol- 1.1.1.100): 3- phosphatidylcholine L-isoleucine degradation I L-threonine L-glutamine L-tyrosine degradation I L-histidine L-phenylalanine L-serine L-cysteine L-alanine enopyranuronoside undecaprenyldiphospho--N-acetylmuramyl- acyl-carrier protein sn-glycerol palmitoleoyl- 3-hydroxyacyl-CoA a DNA containing Glutamyl-tRNA(Gln) hydratase -undecaprenyl 2-phospho-D-glycerate L-tryptophan hydratase [isoleucine (EC acyl-carrier protein an alkylated a (2E,7Z)-hexadeca- an N-terminal an N-terminal reductase reductase (EC 2.5.1.29): Octaprenyl- siroheme biosynthesis adenosyltransferase Methenyltetrahydrofolate Methenyltetrahydrofolate Thiamin-phosphate protein] 3-phosphate oxoacyl-[acyl-carrier biosynthesis VI degradation I degradation I degradation II degradation degradation degradation II degradation IV Beta N-acetyl- N-acetyl-(N-acetyl-β-D- adenosyl-cob(III) 3-phosphate sn-glycerol dehydrogenase an apurinic/ met met amidotransferase clustered cobalt-precorrin-5A diphosphate a [chaperone-ATP]- Cobyrinic acid A,C- 3,4-dihydroxy- Methylenetetrahydrofolate a (6S)-5- 3-oxoacyl-[acyl-carrier- degradation I (6Z,9Z,12Z,15Z,18Z,21Z)-3- UDP triphosphate nucleobase 2,7-dienoyl-[acp] L-valyl-[protein] glycyl-[protein] [isoleucine (EC 1.17.1.2) (EC 1.17.1.2) diphosphate synthase (EC (EC 2.5.1.17): Serine cyclohydrolase (EC 3.5.4.9) cyclohydrolase (EC pyrophosphorylase synthase, dehydrogenase protein] reductase glucosaminidase glucosaminyl)muramoyl- yrinate a,c-diamide 3-phosphate (EC 1.1.1.35): 3- apyrimidinic site subunit B (EC with de [co-chaperone]- diamide synthase CDS 2-butanone dehydrogenase a CDP- Enolase (EC val II (anaerobic) (via anthranilate) oxotetracosahexaenoyl-CoA : 4-hydroxy- : 4-hydroxy- Undecaprenyl- formyltetrahydrofolate protein] synthase, KASI (EC sn-glycerol choline Activation/ ile tyr L-alanyl-γ-D-glutamyl-L- 6.3.5.7): Aspartyl- 3-hydroxyacyl- 4-phosphate uroporphyrinogen-III ATP:Cob(I)alamin hydroxymethyltransferase : Methylenetetrahydrofolate 5-formyltetrahydrofolate 3.5.4.9): G1RHH-2555 (EC 2.5.1.3): [+ 3 isozymes] diacylglycerol 4.2.1.11): thr gln his ala (EC 3.2.1.52): hydroxyacyl-CoA Putative diphosphatase Octaprenyl diphosphate [scaffold protein- hydrogenobyrinate a,c-diamide (NADP+) (EC 1.5.1.5) / KASII (EC 2.3.1.179): 2.3.1.41): 3-phosphate ser cys 4-deoxy-L- 3-methylbut- 3-methylbut- synthase (EC 2-octaprenylphenol adenosyltransferase (EC 2.1.2.1): Serine dehydrogenase Thiamin-phosphate Phosphatidylcholine Enolase (EC Inactivation/ Branched-chain Imidazole glycerol Biosynthetic phe trp Beta N-acetyl- lysyl-D-alanyl-D-alanine 3-oxo-2-(cis-2'-pentenyl)dehydrogenase (EC tRNA(Asn) CoA (EC 3.6.1.27): synthase (EC 2.5.1.90) / (2Fe-2S)] complex Uroporphyrinogen- Methenyltetrahydrofolate cyclo-ligase (EC 6.3.3.2): Methylenetetrahydrofolate 3-oxoacyl-[acyl-carrier- a (3R,11Z)-3-hydroxy- Branched-chain Cystathionine Alanine erythro-hex-4- threonine 2-enyl 2-enyl (EC hydroxymethyltransferase (EC pyrophosphorylase 3-oxoacyl- synthase (EC 2.7.8.24) Interconversion amino acid L-serine Aromatic L-serine glucosaminidase amidotransferase dehydrogenase thr thr 4.1.99.12) / GTP III methyltransferase cob(II)yrinate a,c-diamide- cyclohydrolase (EC 3.5.4.9) 5-formyltetrahydrofolate dehydrogenase icos-11-enoyl-[acp] 4.2.1.11) CDS amino acid phosphate Aspartate dehydrogenase -cyclopentane-1-(3- efflux diphosphate diphosphate Undecaprenyl- Dimethylallyltransferase Aerobic protein] synthase, [acyl-carrier- : Phosphatidylcholine dehydratase, amino acid dehydratase, gamma-lyase enopyranuronate an L-glutaminyl- (EC 1.1.1.35): 3- cobalt-precorrin-5B cyclohydrolase 2-octaprenylphenol (EC 2.1.1.107): cyclo-ligase (EC (NADP+) (EC 1.5.1.5) / (EC oleandomycin aminotransferase aminotransferase synthase cyclase aminotransferase (EC 1.4.1.1) N,N'- (EC N,N',N''- oxohexanoyl)-CoA diphosphatase (EC 2.5.1.1) / (2E,6E)- cobaltochelatase: [corrinoid adenosyltranferase] : Methylenetetrahydrofolate thiamine beta subunit urocanate (EC 4.4.1.1): Gln protein hydroxylase: Methylenetetrahydrofolate protein] 3-hydroxyacyl-[acyl- synthase (EC 2.7.8.24) phosphoenolpyruvate activation/ (EC 2.6.1.42): subunit (EC 4.1.3.-) aminotransferase (EC 2.6.1.1) beta subunit N-Formyl-L- [tRNA ] hydroxyacyl-CoA (EC 3.6.1.27) farnesyl diphosphate II (EC 3.5.4.25) Uroporphyrinogen- dehydrogenase Methenyltetrahydrofolate phosphate a 3-oxooctanoyl-[acp] a 1-acyl-sn (EC 2.6.1.42): : Alanine diacetylchitobiose triacetylchitotriose Aerobic 2-octaprenyl-3- dehydrogenase synthase, carrier-protein] a phosphatidylcholine Branched-chain (EC 4.3.1.17) beta (EC 2.6.1.57) (EC 4.3.1.17) Cystathionine kynurenine dehydrogenase di-trans,octa-cis a [chaperone- : 3,4-dihydroxy- III methyltransferase a 5,10- cyclohydrolase (EC 3.5.4.9) -glycerol 3- inactivation Branched-chain : Imidazole glycerol : Aspartate dehydrogenase Methionine DMAPP IPP synthase (EC 2.5.1.10) an [2Fe-2S] cobaltochelatase CobT a 5-methyltetrahydrofolate (NADP+) (EC 1.5.1.5) / dehydratase, FabA Pyruvate amino acid / L-serine : Biosynthetic / L-serine gamma-lyase (4S,5S)-4,5- Beta- (EC -undecaprenyl ADP]-[disordered- 2-butanone methyl-6-methoxy- (EC methylenetetrahydrofolate : Methylenetetrahydrofolate 3-oxoacyl-[acyl-carrier 3-oxoacyl- phosphate amino acid phosphate synthase aminotransferase (EC 1.4.1.1) CDS / Geranylgeranyl subunit (EC Aerobic a 5,10- Aminoacyl-tRNA Charging kinase (EC oleandomycin dehydratase, dehydratase, (EC 4.4.1.1) dihydroxy-2,6- hexosaminidase 3-oxo-(9Z)- ABC cluster protein 4-phosphate 1,4-benzoq cob(I)yrinate a,c-diamide- Methenyltetrahydrofolate form (EC 4.2.1.59) aminotransferase Aromatic amino acid (EC 2.6.1.1) 2-aminoprop- pyruvate met met phosphate pyrophosphate form scaffold cobaltochelatase [+ 2 isozymes] methenyltetrahydrofolate dehydrogenase protein] reductase (EC [acyl-carrier- 1-acyl-sn-glycerol- aminotransferase [+ 20 isozymes] (EC 3.2.1.52): transporter Isopentenyl- cobalt-precorrin-6A 3-(all-trans 5,10- cyclohydrolase (EC 3.5.4.9) a 10- : 3-hydroxyacyl- 2.7.1.40): alpha subunit 4-imidazolone- alpha subunit 2-enoate dioxohexanoate hexadecenoyl-CoA protein] complex precorrin-1 [corrinoid adenosyltranferase] 1.1.1.100): G1RHH-1018 protein] 3-phosphate [+ 2 isozymes] [+ 2 isozymes] glu 3-(4-hydroxyphenyl)[+ 2 isozymes] [+ 8 isozymes] ATP-binding diphosphate synthetase (EC 2.5.1.29) CobS subunit (EC 3,4-dihydroxy- -octaprenyl) methylenetetrahydrofolate : Methylenetetrahydrofolate formyltetrahydrofolate thiamine [acyl-carrier-protein] tRNA charging Pyruvate (S)-3-methyl-2- (EC 4.3.1.17): 5-propanoate 3-phenyl-2- (EC 4.3.1.17): G1RHH-2604 synthase, acyltransferase gln glucosyl- L-kynurenine delta- Cobalt-precorrin- : Octaprenyl diphosphate Cob(I)alamin diphosphate [+ 3 isozymes] glutaminyl-tRNA kinase (EC 3-methyl-2- oxopentanoate G1RHH-2694 pyruvate oxopropanoate G1RHH-2694 2-butanone benzene-1,2-diol Uroporphyrinogen- reductase (EC 1.5.1.20): 5,10- dehydrogenase Phosphoribosylglycinamide 2-aminoprop- Beta N-acetyl- 6x reductase synthase (EC cob(II)yrinate a,c-diamide adenosyltransferase KASII (EC (EC 2.3.1.51): 1- 3-hydroxyacyl-[acyl- Arginyl-tRNA biosynthesis via transamidation oleandomycin 1-stearoyl- 1-palmitoyl- 1-myristoyl- (S)-3- L-lysine isomerase 4-phosphate 3-demethylubiquinone- methylenetetrahydrofolate 2.7.1.40) CDS oxobutanoate [+ 3 isozymes] glucosaminidase a peptidoglycan ditrans,octacis- a reduced 3S-(4-hydroxyphenyl)-3- 5-cis, 7-trans-3-oxo- (S)-3-hydroxy-(7Z) lys lys III methyltransferase formyltransferase (EC 2.1.2.2) a (3R)-3-hydroxyoctanoyl-[acp] 2.3.1.179): acyl-sn-glycerol- carrier-protein] synthetase (2Z)-2-aminobut- 2-enoate Kynureninase 2-dehydro- a carboxy-adenylated- phytenate a 2,3,4-saturated a 2,3,4-saturated 2- 5'-chloro-5'-deoxyadenosine O-acetyl-L- a (3R,5Z)-3-hydroxy- α-D-mannose 1-(18-hydroxyoleoyl)- a (2E,9Z)-octadeca- glutathione permease (EC 5.3.3.2): (EC 1.3.1.54): an [Fe-S cluster a [disordered- synthase (EC 9 3-methyltransferase (EC 2.5.1.17): reductase base-degraded Multidrug (EC 3.2.1.52): a (3Z)-dodec-3-enoyl-[acp] a malonyl-[acp] AsbD acyl-carrier protein coenzyme A cys with (L-alanyl- undecaprenyldiphospho- electron-transfer ubiquinone-6 an oleoyl-[acp] sn-glycerol a palmitoyl-[acp] sn-glycerol a palmitoleoyl-[acp] sn-glycerol methanethiol hydroxy-propanoyl-CoA tetradecadienoyl-CoA hydroxyhexadecanoyl- -tetradecenoyl-CoA (EC 2.1.1.107): : Phosphoribosylglycinamide 3-oxoacyl- 3-phosphate dehydratase, FabZ 2-enoate 2-iminopropanoate (EC 3.7.1.3): 3-deoxy-D- [ThiS sulfur-carrier protein] fatty acyl-[acp] lysophosphatidate homoserine tetradec-5-enoyl-[acp] GDP sn-glycrol 3-phosphate 2,9-dienoyl-[acp] Isopentenyl- Cobalt-precorrin- all-trans- biosynthesis form [Fe-S] cluster (EC 2.1.1.64): 3- Cob(I)alamin (EC 6.1.1.19): glu pyruvate resistance γ-D-glutamyl-L- N-acetyl-(N-acetyl-β-D- Long-chain-fatty-acid-- flavoprotein 3-phosphate Purine nucleoside 3-phosphate 3-phosphate Enoyl-CoA 3-ketoacyl- 1-phosphate CoA 4.1.99.12) / GTP Uroporphyrinogen- thiamine salvage N-formimino- gluconate Beta N-acetyl- 3-oxoacyl-[acyl-carrier- Holo-[acyl-carrier protein] Cysteine desulfurase Electron transfer 1-acyl-sn-glycerol- 1-acyl-sn-glycerol- 1-acyl-sn-glycerol- 1-acyl-sn-glycerol- O-acetylhomoserine 3-hydroxyacyl-[acyl- 1-acyl-sn-glycerol- Enoyl-[acyl- Enoyl-CoA 6x reductase (EC octaprenyl adenosyltransferase 5,10- 3-hydroxyacyl-[acyl-carrier- [acyl-carrier- 1-acyl-sn-glycerol- form (EC 4.2.1.59) Arginyl-tRNA G1RHH-1801 CoA ligase (EC 6.2.1.3) phosphorylase Enoyl-CoA diphosphate chaperone]-ATP scaffold protein] cyclohydrolase demethylubiquinone- a tetrahydrofolate arg protein 2-methylbutanoyl-CoA homogentisate L-glutamate phenylacetaldehyde glucosaminidase protein] synthase, synthase (EC 2.7.8.7) (EC 2.8.1.7): lysyl-D-alanyl- glucosaminyl)muramoyl- 3-phosphate 3-phosphate 3-phosphate 3-phosphate sulfhydrylase hydratase [isoleucine CoA thiolase carrier-protein] Mannose-1- 3-phosphate carrier-protein] hydratase III methyltransferase methylenetetrahydrofolate formylaminopyrimidine protein] dehydratase, protein] : 3-hydroxyacyl- synthetase (EC 2-dehydro-3- flavoprotein- hydratase delta- diphosphate II (EC 3.5.4.25) 9 3-methyltransferase (EC 3-phosphate Glutamyl- norM: (EC KASI (EC 2.3.1.41): 3- : Holo-[acyl-carrier Cysteine desulfurase D-alanine) L-alanyl-Cell γdivision-D-glutamyl-L- : Long-chain-fatty- acyltransferase acyltransferase (EC 2.4.2.1): acyltransferase acyltransferase (EC 2.5.1.49) / O- degradation] (EC 2.3.1.16) dehydratase, FabA phosphate acyltransferase reductase [isoleucine Putative (EC NAD salvage pathway I (PNC VI cycle) acyl carrier protein activation synthase, isobutanoyl-CoA L-proline degradation anthranilate deoxygluconate ubiquinone isomerase cobalt-precorrin-6B D-ribulose 2-methoxy- reductase (EC 1.5.1.20): 5,10- coenzyme A biosynthesis I (prokaryotic) FabZ form (EC 4.2.1.59) acyltransferase [acyl-carrier-protein] 6.1.1.19) CDS tRNA(Gln) Multidrug S-2-methylbutryl- Aldehyde 2-iminopropanoate pentapeptide lysyl-D-alanyl-D-alanineprotein FtsI acid--CoA ligase (EC Purine nucleoside @ Acetyl-CoA guanylyltransferase [isoleucine preQ preQ0 preQ : 3,4-dihydroxy- ATP:Cob(I)alamin Arg N-acetyl-D- oxoacyl-[acyl-carrier- protein] synthase (EC (EC 2.8.1.7) CDS (EC 2.3.1.51): 1- (EC 2.3.1.51): 1- (EC 2.3.1.51): 1- (EC 2.3.1.51): 1- succinylhomoserine (EC 4.2.1.17) / 3- form (EC 4.2.1.59) (EC 2.3.1.51): [NADH] (EC degradation] 0 0 [+ 2 isozymes] methylenetetrahydrofolate : 3-hydroxyacyl- an L-arginyl-[tRNA ] kinase (EC oxidoreductase 5-phosphate 2-butanone 6-(all-trans- (EC 2.3.1.51): an (2E,11Z)-icosa- synthetase resistance isobutyryl- CoA:FAD 2-iminobutanoate dehydrogenase [Peptidoglycan phosphorylase (EC hydroxyacyl-CoA acetyltransferase (GDP) (EC 2.7.7.22) degradation] transporter adenosyltransferase + aminomethylpyrimidine a (9Z)-3-oxohexadec- pyruvate glucosamine protein] synthase, Long-chain-fatty-acid-- (EC 1.5.5.1): acyl-sn-glycerol- acyl-sn-glycerol- acyl-sn-glycerol- acyl-sn-glycerol- sulfhydrylase : 3-hydroxyacyl- G1RHH-1918 1.3.1.9): Enoyl- (EC 4.2.1.17) / 3- octaprenyl)phenol reductase NAD [acyl-carrier-protein] a tRNA Arg oxidoreductase: 2.7.1.45): 2- 4'-phosphopantetheinyl Cysteine desulfurase (EC 4.2.1.17) / 3- DMAPP adenosylcobalamin 4-phosphate precorrin-2 (EC 2.5.1.17): (R)-4'-phosphopantothenate an apo acyl-carrier protein 9-enoyl-[acp] G1RHH-1918 2,11-dienoyl-[acp] (EC 6.1.1.24) protein CoA:FAD (EC 1.2.1.3) synthetase] CoA ligase (EC 6.2.1.3) 3-phosphate 3-phosphate Purine nucleoside 3-phosphate 3-phosphate (EC 2.5.1.48): dehydrogenase (EC 2.3.1.9): 3- [acyl-carrier-protein] : G1RHH-2577 [acyl-carrier- hydroxyacyl-CoA superpathway of b heme 3,4-dihydroxy- pro 4-maleyl-acetoacetate N-formyl- dehydro-3- 3-oxoacyl-[acyl-carrier- transferase entD (EC 2.8.1.7), SufS Electron transfer 1-acyl-sn-glycerol- salvage from cobalamin 2,5-diamino-6- 2-octaprenyl-6- Thiaminase II 3-hydroxyacyl-[acyl-carrier- a 1,2-diacyl- : Glutamyl- norM CDS oxidoreductase: Butyryl-CoA : Aldehyde (EC 2.4.1.129) G1RHH-2713 (EC 1.1.1.35) / 3- ketoacyl-CoA hydroxyacyl-CoA thiazole biosynthesis II (aerobic bacteria) biosynthesis from glycine 2-butanone ATP:Cob(I)alamin Phosphopantothenoylcysteine 4'-phosphopantetheinyl Enoyl-[acyl-carrier- Glycolysis L-glutamate deoxygluconate protein] synthase, (EC 2.7.8.-); Holo- subfamily: Cysteine : Long-chain-fatty- flavoprotein- 1-acyl-sn-glycerol- phosphorylase 3-hydroxyacyl-[acyl- Mannose-1- 3-phosphate protein] reductase dehydrogenase (EC 3.5.99.2) protein] dehydratase, 3-oxoacyl- sn-glycerol dehydrogenase Proline 1-acyl-sn-glycerol- 1-acyl-sn-glycerol- 1-acyl-sn-glycerol- thiolase (EC dehydrogenase Taurine Octaprenyl-diphosphate 4-phosphate (5-phospho-D- methoxyphenol Siroheme synthase / adenosyltransferase decarboxylase (EC 4.1.1.36) / transferase entD tRNA(Gln) glucosyl- Butyryl-CoA dehydrogenase pyruvate : Cell division acid--CoA ligase (EC ubiquinone (EC 2.4.2.1): hydroxybutyryl-CoA phosphate (EC 1.1.1.35) / cobalt-precorrin-7 5-methylbenzimidazolyl adenosylcobamide : Thiaminase [acyl-carrier 3-phosphate protein] reductase (EC 1.3.99.2) dehydrogenase Maleylacetoacetate N-formylglutamate L-arginine degradation III (arginine kinase (EC KASII (EC 2.3.1.179): [acyl-carrier protein] desulfurase (EC an oxidized 3-phosphate 3-phosphate 3-phosphate 3-phosphate [+ 5 isozymes] carrier-protein] acyltransferase [+ 2 isozymes] (EC 1.1.1.35) / transport synthase (EC 2.5.1.-) / cob(I)alamin ribosylamino) hydroxylase Precorrin-2 oxidase (EC Phosphopantothenoylcysteine NADH pyrophosphatase (EC 2.7.8.-); Holo- FabA form (EC 4.2.1.59) synthetase dehydrogenase (EC 1.2.1.3) CDS protein FtsI Purine nucleoside epimerase (EC 2.3.1.16) @ 3-hydroxybutyryl- synthase (EC NAD synthetase (EC biosynthesis from adenosylcobinamide-GDP [NADH] (EC 1.3.1.9) oleandomycin 2-oxobutanoate isomerase (EC 3-oxoacyl-[acyl-carrier- synthase, alternative (EC 2.8.1.7), SufS + guanylyltransferase (EC 2.3.1.51): 1- gly (EC 3.6.1.22): NADH II (EC : 3-hydroxyacyl- protein] glycolysis III (from glucose) (EC 1.5.99.8) deformylase decarboxylase/agmatinase pathway) a peptidoglycan diphosphate H ubiquinol-6 electron-transfer acyltransferase acyltransferase acyltransferase acyltransferase acetate met dehydratase, FabZ an oleoyl-[acp] 3-hydroxybutyryl- a taurine system taurine Dimethylallyltransferase cys 4.1.99.12) / GTP pyrimidin- (EC 1.14.13.-) (EC 1.3.1.76) / synthetase (EC 6.3.2.5): [acyl-carrier protein] Phosphatidate Cysteinyl-tRNA (EC (EC 1.3.99.2) (E)-2- [+ 5 isozymes] KDGP [Peptidoglycan AMP phytenoyl-CoA phosphorylase (EC 5.1.2.3): Enoyl-CoA [+ 3 isozymes] (GDP) (EC CoA epimerase HX 6.3.1.5) / Glutamine 3.5.99.2) CDS reductase : Enoyl-[acyl-carrier- (Proline oxidase) / 5.2.1.2) / Glutathione (EC 3.5.1.68): N- protein] synthase, 2.7.8.7): G1RHH-1017 flavoprotein (EC 2.3.1.51): (EC 2.3.1.51): (EC 2.3.1.51): (EC 2.3.1.51): form (EC 4.2.1.59) acyl-sn-glycerol- CoA epimerase permease (EC 2.5.1.1) / 5-aminolevulinate 4(3H)-one ; 2-octaprenyl- Sirohydrochlorin adenosyl-cob(III)yrinate a,c-diamide Phosphopantothenoylcysteine pyrophosphatase synthase, alternative (EC [acyl-carrier-protein] cytidylyltransferase synthetase methylcrotonoyl-CoA AMP ala a thiocarboxy-[ThiS-Protein] with (L-alanyl- [+ 2 isozymes] hydratase [isoleucine (3Z,5E)-dodeca- (EC 5.1.2.3) S cyclohydrolase amidotransferase chain 5-methylbenzimidazole NaMN (EC 1.1.1.100) protein] reductase an L-glutamyl- Delta-1-pyrroline- S-transferase: di-trans,octa-cis G1RHH-1918 G1RHH-1918 5-chloro-5-deoxyribose G1RHH-1918 G1RHH-1918 acetyl-CoA : 3-hydroxyacyl- 2.7.7.22): Mannose- 3-phosphate protein Geranyltranstransferase synthase (EC 2.3.1.37) Diaminohydroxyphosphoribosylaminopyrimidine 3-methyl-6- (EC 3.6.1.22) CDS (EC 2.7.7.41): (EC 6.1.1.16): D-glucopyranose methylacrylyl-CoA formylglutamate phenylacetate arg acyl-carrier protein a (5Z)-3-oxo-tetradec-5-enoyl-[acp] a holo-[AsbD acyl-carrier protein] 3',5'-ADP γ-D-glutamyl-L- 1-stearoyl-2- a 2,3,4-saturated 1-myristoyl-2- 3,5-dienoyl-CoA 1-[18-hydroxyoeoyl]-2- (EC 5.1.2.3) Cysteine cob(II)alamin II (EC 3.5.4.25) ferrochelatase decarboxylase of NAD synthetase: 2.7.8.7): G1RHH-1017 4-amino-2-methyl-5- Gln Maleylacetoacetate -undecaprenyl adenine dipalmitoyl 1-phosphate : Enoyl-CoA : 5-aminolevulinate Cobyric acid (R)-4'-phosphopantothenoyl- a (2E)-oct-2-enoyl-[acp] : G1RHH-1018 [+ 2 isozymes] [tRNA ] Enoyl-CoA 5-carboxylate deformylase (EC Biosynthetic arginine lysyl-D-alanyl- acyl-carrier protein oleoyl-sn-glycerol 1-phosphate acyl-carrier protein 3-hydroxyacyl-CoA [acyl-carrier-protein] [18-hydroxy-lioleoyl]-sn : Enoyl-CoA (farnesyldiphosphate cobalt-precorrin-8 desulfurase deaminase (EC 3.5.4.26) / 5-amino-6-(5- methoxy-1,4- (EC 4.99.1.4) / Nicotinate-nucleotide-- pyrimidinemethanol Phosphatidate Cysteinyl-tRNA 1,2-diacyl-sn acyl-carrier protein palmitoleoyl- guanylyltransferase hydratase Taurine : 3,4-dihydroxy- synthase (EC L-cysteine NAD synthetase (EC Holo-[acyl-carrier protein] cys Glucokinase (EC oleandomycin hydratase dehydrogenase isomerase (EC 5.2.1.2) diphosphate acyl-carrier protein phosphatidate dehydrogenase a (2E,5Z)-tetradeca- α hydratase synthase) (EC 2.5.1.10) Cob(I)alamin synthase (EC 2.3.1.37) phosphoribosylamino)uracil reductase (EC 1.1.1.193) benzoquinol nicotinate adenine dinucleotide [+ 3 isozymes] cytidylyltransferase synthetase Aspartyl-tRNA(Asn) Enoyl-CoA decarboxylase (EC D-alanine) 3-phosphate -glycerol 3- sn-glycerol GDP- -D- -glycerol 3-phosphate [isoleucine (EC 2.8.1.7) 2-butanone Uroporphyrinogen- 6.3.5.10): Cobyric 6.3.1.5) / Glutamine NMN dimethylbenzimidazole synthase (EC 2.7.8.7) a gondoyl-[acp] 2.7.1.2): Glucokinase [isoleucine propanoyl-CoA (EC 1.1.1.35): 3- 2,5-dienoyl-[acp] transport 5-aminolevulinate hydroxylase Phosphopantothenoylcysteine Enoyl-[acyl-carrier-protein] a (3R,9Z)-3- (EC (EC 6.1.1.16) amidotransferase hydratase (EC 1.5.1.12) glu 4.1.1.19): G1RHH-2085 pentapeptide phosphate 3-phosphate mannose [isoleucine / Geranylgeranyl , SufS adenosyltransferase 4-phosphate : Diaminohydroxyphosphoribosylaminopyrimidin III methyltransferase phosphoribosyltransferase (EC 2.7.1.2) CDS 4-fumaryl-acetoacetate taurine ATP- taurine 5-amino-6-(5- acid synthase : Holo-[acyl-carrier reductase [NADH] (EC hydroxyhexadec- an L-cysteinyl-[tRNA Cys ] [isoleucine degradation] : Proline agmatine hydroxyacyl-CoA 3-hydroxyacyl- pyrophosphate synthetase subfamily: (EC 2.5.1.17): (EC 1.14.13.-): (EC 2.1.1.107): decarboxylase (EC 4.1.1.36) / (EC 2.4.2.21): G1RHH-2709 subunit: Aspartyl- [+ 4 isozymes] binding Porphobilinogen (EC 6.3.5.10) CDS Nicotinate-nucleotide protein] synthase (EC 9-enoyl-[acp] Phosphatidate (EC 4.2.1.17) / 3- dehydrogenase dehydrogenase (EC (EC 2.5.1.29): Octaprenyl- Cob(I)alamin 3,4-dihydroxy- phospho-D- 2-octaprenyl-6- Phosphopantothenoylcysteine 1.3.1.9): Enoyl-[acyl- Cys tRNA(Asn) degradation] (2E)- CoA Cysteine synthase (EC 4.2.1.24) Siroheme synthase / adenylyltransferase cytidylyltransferase a tRNA D-glucopyranose 6-phosphate hydroxyacyl-CoA L-arginine degradation Arginase/agmatinase/ 3-(4-hydroxyphenyl)- protein TauB cobyrinate ribosylamino)uracil methoxyphenol (R)-1-amino-2-propanol synthetase (EC 6.3.2.5): 5-methylbenzimidazole a holo acyl-carrier protein carrier-protein] reductase 3-hydroxyacyl- gln (EC 4.2.1.17) / 3- (EC 1.5.99.8) hexadecenoyl-CoA dehydrogenase diphosphate synthase (EC desulfurase adenosyltransferase : Porphobilinogen 2-butanone Precorrin-2 oxidase (EC 2.7.7.18): adenosylcobinamide-GDP (EC 2.7.7.41): amidotransferase (S)-1-pyrroline- 3-oxo-propanoyl-CoA Diaminohydroxyphosphoribosylaminopyrimidine adenosylcobyrate ribotide phosphate [+ 2 isozymes] [acyl-carrier- hydroxyacyl-CoA dehydrogenase VII (arginase 3 pathway) formimionoglutamate (EC 1.1.1.35): 3- Sulfate (EC 2.8.1.7) (EC 4-phosphate hydroxylase O-2-phosphate Phosphopantothenoylcysteine Aspartyl-tRNA(Asn) Glucose-6-phosphate propanoyl phosphate 5-carboxylate fumarate acetoacetate sulfate Cobyrinic acid synthase (EC 4.2.1.24) Nicotinate-nucleotide Phosphatidate (EC 1.1.1.35) / hydrolase: Arginase/ sulfate Octaprenyl diphosphate synthase (EC deaminase (EC 3.5.4.26) / 5-amino-6-(5- 2-methoxy-6-all Siroheme synthase / decarboxylase protein] amidotransferase Imidazole isomerase (EC 5.3.1.9) dehydrogenase hydroxyacyl-CoA permease , SufS ATP:Cob(I)alamin Adenosylcobinamide- adenylyltransferase cytidylyltransferase 3-hydroxybutyryl- agmatinase/ synthase (EC 2.5.1.90) / A,C-diamide phosphoribosylamino)uracil reductase (EC 1.1.1.193) Precorrin-2 oxidase Cobalamin synthase an octanoyl-[acp] dehydratase, glycerol : Glucose-6-phosphate (EC 1.1.1.35) / arg dehydrogenase porphobilinogen 4.1.99.12) / GTP trans-octaprenyl- phosphate synthase (EC Acetate formimionoglutamate Dimethylallyltransferase synthase: Cysteine adenosyltransferase : Diaminohydroxyphosphoribosylaminopyrimidin 4'-phosphopantetheine FabA form Aspartyl-tRNA(Asn) phosphate isomerase (EC 5.3.1.9) 3-hydroxybutyryl- CoA epimerase (EC cyclohydrolase 1,4-benzoquinol (EC 1.3.1.76) / (EC 6.3.1.10): (EC 2.7.8.26): gln kinase (EC (EC 2.5.1.1) / (2E,6E)- Cobyrinic acid desulfurase a ThiS sulfur- (EC 2.5.1.17): Porphobilinogen 5-amino-6-(5- NaMN nicotinamide glutathione- 3-oxoacyl-[acyl-carrier- (EC 4.2.1.59): a CDP- amidotransferase synthase CoA epimerase (EC 5.1.2.3) [+ 4 isozymes] 3-oxo-(7Z)- Sulfate II (EC 3.5.4.25) Sirohydrochlorin Adenosylcobinamide- Phosphopantetheine Nicotinamidase G1RHH-2708 2.7.2.1): L-glutamate-5- sulfate sulfate farnesyl diphosphate A,C-diamide (EC 2.8.1.7) carrier protein ATP:Cob(I)alamin deaminase (EC 2.5.1.61) phospho-D- glutathione- peroxide protein] synthase, 3-hydroxyacyl- diacylglycerol subunit B (EC cyclase F6P (EC 5.1.2.3) : Enoyl-CoA Arginase/agmatinase/ tetradecenoyl-CoA permease : 3,4-dihydroxy- ferrochelatase an L-glutaminyl-[tRNA Gln ] Acetate semialdehyde synthase CDS adenosyltransferase ribitylamino)uracil phosphate adenylyltransferase (EC 3.5.1.19): Coα-[α-(5-methylbenzimidazolyl) glutaredoxin 6.3.5.6) @ hydratase putrescine synthase (EC 2.5.1.10) : Cysteine : Porphobilinogen 2-butanone (EC 4.99.1.4) / redox reactions KASI (EC 2.3.1.41): 3- [acyl-carrier- Putative subunit : Enoyl-CoA formimionoglutamate 6-methoxy-3- synthase (EC (EC 2.7.7.3): Nicotinamidase Gln kinase (EC / Geranylgeranyl desulfurase (EC deaminase (EC 2.5.1.61) NAD de novo biosynthesis ]-Coβ-adenosylcobamide redox reactions oxoacyl-[acyl-carrier- protein] phosphatidylglycerophosphate a tRNA Glutamyl-tRNA(Gln) hydratase [isoleucine L-citrulline degradation hydrolase: Arginase/ 4-phosphate Uroporphyrinogen- GSSG (EC 4.1.3.-) 2.7.2.1) CDS Proline L-phenylalanine degradation I (aerobic) cob(II)yrinate a,c-diamide cob(II)alamin- methyl-2-all- 10 Phosphopantetheine (EC 3.5.1.19) CDS 1-cis-vaccenoyl- S-(2-hydroxyacyl) 1-cis-vaccenoyl- 1-stearoyl- a peptide with an N-terminal-L-methionyl- 3-benzyl-3,6 - a [lipoyl-carrier (1S,2R)-1- pyrophosphate (EC 2.8.1.7) I (from aspartate) III methyltransferase N -formyl-tetrahydrofolate biosynthesis 5'-phosphate glutathione protein] synthase, synthase: Putative amidotransferase : Imidazole [isoleucine dehydrogenase L-tryptophan degradation to agmatinase/ an apo-[methylmalonyl- α,ω-9Z-octadecenedioate linoleate methionol a cis- O-phospho- hydantoin uroporphyrinogen-III a (7Z)-3-oxo- 1-deoxy-L- trans-octaprenyl- adenosyl-cobinamide phosphate adenylyltransferase (EC Nicotinate [+ 4 isozymes] a (7Z)-hexadec-7-enoyl-[acp] a malonyl-[acp] a palmitoyl-[acp] a malonyl-[acp] biotin a palmitoleoyl-[acp] sn-glycerol- sn-glycerol- a palmitoyl-[acp] sn-glycerol an N-terminal cys bis(cysteinylglycine) protein] N 6 -[(R) C-(indol-3- His/Glu/Gln/ synthetase (EC 2.5.1.29) CDS a carboxy- [corrinoid preuroporphyrinogen 3-hydroxyacyl- phosphatidylglycerophosphate subunit B (EC Acetate formimionoglutamate CoA:pyruvate carboxytransferase] a purine ribonucleoside glutathione vaccenoyl-[acp] L-homoserine L-cysteinyl-[protein] GTP H O ser hexadec-7-enoyl-[ac (EC 2.1.1.107): phosphoribosyltransferase 3-oxoacyl-[acyl-carrier- glycerol β-D-fructose 1,6-bisphosphate (2S,3S)-3-hydroxy-2- (EC 1.5.99.8) 2-amino-3-carboxymuconate (6R)-4a-hydroxy- 2 adenosyltranferase] glycero-tetrulose ARP 1,4-benzoquinol [acyl-carrier- 6.3.5.7): Aspartyl- [+ 4 isozymes] kinase (EC L-citrulline Pterin-4-alpha- 3-oxoacyl-[acyl-carrier- 3-oxoacyl-[acyl-carrier- Biotin--protein ligase Long-chain-fatty- Long-chain-fatty-acid-- Alcohol dehydrogenase, 1-acyl-sn-glycerol-3-phosphate Hydroxyacylglutathione 1-acyl-sn-glycerol-3-phosphate 1-acyl-sn-glycerol-3-phosphate Xaa-L-prolineXaa-Pro O-acetylhomoserine Hydantoinase/ Methionine Siroheme synthase / - 6-(hydroxymethyl) -dihydrolipoyl]- yl)glycerol Arg/opine : Octaprenyl diphosphate an [L-cysteine adenylated- asp Siroheme synthase / a tetrahydrofolate phosphate (Proline oxidase) / semialdehyde Arginase (EC 3.5.3.1) tetrahydrobiopterin Uroporphyrinogen-III 4-phosphate Adenosylcobinamide- 3'-dephospho-CoA (EC 2.4.2.11): Nicotinate protein] synthase, protein] CDP-diacylglycerol-- methylbutanoyl-CoA carbinolamine acid--CoA ligase CoA ligase (EC 6.2.1.3) zinc containing (EC 1.1.1.1) Purine nucleoside hydrolase (EC 3.1.2.6): oxoprolinase family aminopeptidase Precorrin-2 oxidase Nucleoside 5- -diketopiperazineMicrosomal L-lysine 3-phosphate Tryptophan family ABC synthase (EC desulfurase]-S- [ThiS sulfur- 2-octaprenyl- Glutathione glutamate- tRNA(Asn) synthase (S)-3-hydroxy- 2.7.2.1): Delta-1-pyrroline- Ornithine protein] synthase, protein] synthase, (EC 6.3.4.9, EC 6.3.4.10, 3-phosphate 3-phosphate 3-phosphate aminopeptidase sulfhydrylase Dihydrolipoamide synthase (EC 4.2.1.75) L-aspartate Precorrin-2 oxidase phosphate phosphoribosyltransferase (EC Coα-[α-(5-methylbenzimidazolyl) a reduced KASII (EC 2.3.1.179): glycerol-3-phosphate 3- : G1RHH-1884 (EC 6.2.1.3): Long- : Long-chain-fatty- : Alcohol dehydrogenase, phosphorylase Hydroxyacylglutathione protein: Hydantoinase/ triphosphatase dipeptidase glu transporter, glu sulfanyl-L-cysteine carrier protein] 3-methyl-6- reductase dehydratase, amidotransferase isobutanoyl-CoA Acetate trp carbamoyltransferase dehydratase KASI (EC 2.3.1.41): 3- KASI (EC 2.3.1.41): 3- EC 6.3.4.11, EC acyltransferase acyltransferase acyltransferase (EC 3.4.13.9) (EC 2.5.1.49) / O- (EC 3.4.11.18) (EC 1.3.1.76) / dehydrogenase synthase Dephospho-CoA β glutaredoxin 3-oxoacyl-[acyl-carrier- tRNA ligase: Fructose-bisphosphate 5-carboxylate (EC 2.4.2.1): RdgB (dHAPTP, : Uroporphyrinogen- 6,7-dimethyl-8- oxidase: guanylyltransferase nicotinate ]-Co -adenosylcobamide FabZ form phosphatidyltransferase glu [+ 20 isozymes] (EC 4.2.1.96): chain-fatty-acid- acid--CoA ligase (EC zinc containing (EC hydrolase (EC oxoprolinase : Methionine Sirohydrochlorin precursor alpha chain his periplasmic his cob(I)alamin- methoxy-1,4- sirohydrochlorin kinase (EC 2.7.1.24) (EC 1.8.1.7): G1RHH-1889 a 5-phosphooxy- aldolase class I (EC 3-hydroxyisobutyryl- kinase (EC dehydrogenase (EC 2.1.3.3): Ornithine oxoacyl-[acyl-carrier- oxoacyl-[acyl-carrier- 6.3.4.15): G1RHH-1824 (EC 2.3.1.51): 1- (EC 2.3.1.51): 1- (EC 2.3.1.51): 1- : Xaa-Pro succinylhomoserine of 2-oxoglutarate geranyl diphosphate III synthase (EC ribityllumazine Succinate (EC 2.7.7.62): protein] synthase, (EC 2.7.8.5): CDP- glycine cleavage -CoA ligase (EC Purine nucleoside family protein aminopeptidase dITP, XTP- (EC 3.4.13.19) gln His/Glu/Gln/ gln Cysteine [corrinoid benzoquinol Glutaredoxin G1RHH-2698 (EC 4.2.1.59): L-glutamyl- 4.1.2.13): Fructose- CoA hydrolase 2.7.2.1) CDS carbamoyltransferase urea Pterin-4-alpha- protein] synthase, protein] synthase, Biotin--protein ligase Long-chain-fatty-acid-- Alcohol dehydrogenase acyl-sn-glycerol- SAM-dependent acyl-sn-glycerol- acyl-sn-glycerol- aminopeptidase sulfhydrylase ferrochelatase dehydrogenase (EC 4.2.1.20) synthase (EC dehydrogenase Adenosylcobinamide- : Dephospho- diacylglycerol-- [+ 2 isozymes] ammonium (EC 1.5.1.12) L-ornithine phosphorylase (EC specific) (EC : Microsomal arg Arg/opine arg 3 (Grx2): 3-hydroxyacyl- an L-glutamyl-[tRNA Glu ] Gln 2-methylacetoacetyl-CoA N-Formyl-L- (EC carbinolamine Long-chain-fatty- CoA ligase (EC 6.2.1.3) (EC 1.1.1.1): Alcohol 3-phosphate methyltransferase 3-phosphate 3-phosphate (EC 3.4.13.9) CDS (EC 2.5.1.48): Dihydropyrimidinase (EC 3.4.11.18) (EC 4.99.1.4) / (EC 1.8.1.4): : Tryptophan desulfurase adenosyltranferase] uroporphyrinogen-III hydroxylase Siroheme synthase / CoA kinase (EC a 3-oxodecanoyl-[acp] [tRNA ] bisphosphate (EC 3.1.2.4): : Proline 3-oxoacyl-[acyl-carrier- 3-oxoacyl-[acyl-carrier- (EC 6.3.4.9, EC 6.3.4.10, Octaprenyl-diphosphate 2.5.1.78): 6,7- flavoprotein phosphate Glutaredoxin [acyl-carrier- glycerol-3-phosphate propanoate kynurenine carbamoyl phosphate a [glycine-cleavage complex Glycine cleavage dehydratase Purine nucleoside Uroporphyrinogen- 3.6.1.15): dipeptidase synthase family- (EC 2.8.1.7) Cob(I)alamin (EC 1.14.13.-) Precorrin-2 oxidase 2.7.1.24) CDS a tRNA glu aldolase class I (EC G1RHH-2634 dehydrogenase Ornithine protein] synthase, protein] synthase, EC 6.3.4.11, EC acid--CoA ligase : Long-chain-fatty- dehydrogenase 2, in cluster with [+ 2 isozymes] G1RHH-2713 (EC 3.5.2.2): Methionine Dihydrolipoamide synthase (EC 2.5.1.-) / 2-iminosuccinate 6 1-acyl-sn-glycerol- 1-acyl-sn-glycerol- 1-acyl-sn-glycerol- a peptide with Nucleoside 5- 3-benzyl-3,6 - NAD salvage dimethyl-8- 3 (Grx2) CDS protein] 1-(3-sn- 3-ketoacyl- H protein] N -lipoyl-L-lysine system H (6R)-L-erythro-5,6,7,8- L-erythro-7,8- phosphorylase a proteinogenic Dihydropyrimidinase III methyltransferase precursor (EC dehydrogenase of alpha binding , SufS adenosyltransferase Uroporphyrinogen : 2-octaprenyl- (EC 1.3.1.76) / glutathione 3-oxoacyl-[acyl-carrier Aspartyl-tRNA(Asn) (S)-3-hydroxy- (EC 1.5.99.8) cyclodeaminase (EC KASII (EC 2.3.1.179): KASII (EC 2.3.1.179): 6.3.4.15): Biotin--protein (EC 6.2.1.3): Long- acid--CoA ligase (EC (EC 1.1.1.1) CDS 3-phosphate Hydroxyacylglutathione 3-phosphate 3-phosphate aminopeptidase Dimethylallyltransferase pathway III (to ribityllumazine adenosylcobinamide-GDP a protein with phosphatidyl) CoA thiolase protein: Glycine (EC 2.4.2.1): an N-terminal O-acetylhomoserine triphosphatase bis(cysteinyl)- 6- protein subfamily: (EC 2.5.1.17): III decarboxylase 3-methyl- coenzyme A amidotransferase Carbamoyl-phosphate 4.3.1.12): Ornithine tetrahydrobiopterin dihydrobiopterin ligase (EC 6.3.4.9, EC chain-fatty-acid- 3-(methylsulfanyl)propanal hydrolase (EC 3.1.2.6) amino acid (EC 3.5.2.2) CDS (EC 3.4.11.18) (EC 2.1.1.107): gly chain (EC a (3R,7Z)-3-hydrox (EC 2.5.1.1) / nicotinamide riboside) synthase Sirohydrochlorin reduced L- protein] reductase (EC a (2E,9Z)-hexadeca- -sn-glycerol isobutanoate cleavage system 3-oxoacyl-[acyl-carrier- 3-oxoacyl-[acyl-carrier- acyltransferase acyltransferase acyltransferase L-proline sulfhydrylase RdgB (dHAPTP, (hydroxymethyl) Dihydrolipoamide (EC 4.1.1.37): 6-methoxy- subunit: Aspartyl- Triosephosphate (EC 2.3.1.16) synthase large a holo-[methylmalonyl- -CoA ligase (EC AMP diphosphate linoleoyl-CoA Purine nucleoside : SAM-dependent Siroheme synthase / hexadec-7-enoyl-[ac Geranyltranstransferase Cysteine Cob(I)alamin ferrochelatase 1.1.1.100): G1RHH-1018 2,9-dienoyl-[acp] glu cyclodeaminase protein] synthase, protein] synthase, (EC 2.3.1.51): (EC 2.3.1.51): (EC 2.3.1.51): : Methionine -diketopiperazine dehydrogenase Tryptophan + cysteine residues 3-phosphate 3-hydroxyisobutyrate @ Acetyl-CoA H protein CDS phosphorylase (EC (EC 2.5.1.49) / O- N-carbamoylglycine + NADP Uroporphyrinogen 1,4-benzoq tRNA(Asn) isomerase (EC 5.3.1.1) chain (EC 6.3.5.5): (EC 4.3.1.12) CoA:pyruvate carboxytransferase] methyltransferase 2, in aminopeptidase Precorrin-2 oxidase phosphate GDP H (farnesyldiphosphate desulfurase D-glyceraldehyde adenosyltransferase (EC 4.99.1.4) / [+ 3 isozymes] Phosphatidylglycerophosphatase Isoleucyl-tRNA dehydrogenase L-glutamine L-kynurenine acyl-carrier protein a (9Z)-3-oxo-octadec-9-enoyl-[acp] acyl-carrier protein a 3-oxooctadecanoyl-[acp] ω-carboxy-(9Z)- G1RHH-1918 G1RHH-1918 G1RHH-1918 succinylhomoserine (EC 1.8.1.4): synthase Alkaline gly III decarboxylase (EC 6,7-dimethyl-8-(1- Enoyl-[acyl- amidotransferase : Triosephosphate acetyltransferase Carbamoyl-phosphate Glycine AMP diphosphate α-D-ribose-1-phosphate a purine base 1-cis-vaccenoyl- a 2-hydroxy 1,2-dicis- 1-stearoyl- synthase) (EC 2.5.1.10) (EC 2.8.1.7) 3-phosphate (EC quinolinate Uroporphyrinogen- synthetase degradation II [+ 2 isozymes] Glycine cleavage Aromatic Compound Degradation octadec-9-enoyl-CoA glutathione (EC 3.4.11.18) [+ 2 isozymes] Dihydrolipoamide beta chain D-ribityl)lumazine carrier- A (EC 3.1.3.27): isomerase (EC 5.3.1.1) (EC 1.1.1.31): (EC 2.3.1.9): 3- synthase large chain 2-palmitoleoyl- carboxylate acyl-carrier protein vaccenoyl- 2-palmitoyl- sulfhydrylase phosphatase , SufS 3-demethylubiquinol-8 III methyltransferase NAD phosphorylation and dephosphorylation a (3R)-3-hydroxydecanoyl-[acp] Aspartyl-tRNA(Asn) system H dehydrogenase acyl-carrier protein acyl-carrier protein an N-terminal L- precorrin-2 a [lipoyl-carrierdehydrogenase (EC (EC 4.2.1.20) / Geranylgeranyl 1-deoxy-D- ATP:Cob(I)alamin coproporphyrinogen III Phosphatidylglycerophosphatase (EC 6.1.1.5): DHAP D-glyceraldehyde 3-phosphate G1RHH-2635 ketoacyl-CoA sn-glycerol- phosphatidate sn-glycerol (EC 2.5.1.48): O- met (EC 3.1.3.1) Riboflavin protein] amidotransferase Carbamoyl-phosphate [decarboxylating] 6 pyrophosphate synthetase Glycine/ adenosyltransferase (EC 2.1.1.107): A (EC Isoleucyl-tRNA pro protein: Glycine chlorosalicylate degradation acetylhomoserine cysteinyl-[protein] protein]-N - : Tryptophan Cysteine xylulose 5- 3-demethylubiquinone- reductase ile [+ 4 isozymes] thiolase (EC gln salicylate 3-phosphate 3-phosphate : Alkaline D-amino synthase Siroheme synthase / + 3-hydroxyacyl-[acyl-carrier- an L-1- synthase small (glycine cleavage catechol degradation urate lipoyl-L-lysine (EC 2.5.1.29): Octaprenyl- phosphate (EC 2.5.1.17): Coproporphyrinogen NAD synthetase Aspartyl-tRNA(Asn) NAD-dependent L-aspartate cleavage system protocatechuate degradation catechol degradation to sulfhydrylase (EC synthase phosphatase desulfurase eubacterial/ 9 3-methyltransferase [NADH] (EC (S)-methylmalonate- 2.3.1.16) @ Glutamate system P protein) β degradation I diphosphate synthase (EC acid III oxidase, aerobic Precorrin-2 oxidase protein] dehydratase, phosphatidyl- (EC 6.1.1.5) glyceraldehyde-3- 3-hydroxy- chain (EC 6.3.5.5): H protein CDS to -ketoadipate II (ortho-cleavage pathway) conversion 2-hydroxypentadienoate I beta (EC 2.8.1.7) synthase ATP:Cob(I)alamin (EC 2.1.1.64): 3- amidotransferase semialdehyde synthase [NADPH]: degradation I (EC 3.1.3.1) eukaryotic NaMN 1.3.1.9): Enoyl- Ile [+ 3 isozymes] Carbamoyl-phosphate (EC 1.4.4.2): Glycine 5-chlorosalicylate 4-chlorosalicylate to allantoin I L-cystathionine oxidase: adenosyltransferase (EC 1.3.3.3): Alkaline FabZ form (EC 4.2.1.59) sn-glycerol an L-isoleucyl-[tRNA ] subunit B (EC phosphate dehydrogenase L-kynurenine [+ 2 isozymes] chain (EC : Cysteine (EC 2.2.1.7) demethylubiquinone- Siroheme synthase / phosphopantothenate biosynthesis I [acyl-carrier- Glutamate synthase a [glycine-cleavage salicylate D-glyceraldehyde Octaprenyl diphosphate CDS Glycine/ (EC 2.5.1.9) : 3-hydroxyacyl- Ile synthase small chain a [glycine-cleavage complex H dehydrogenase catechol protocatechuate : 1-deoxy-D- (EC Coproporphyrinogen Nicotinate-nucleotide 9 3-methyltransferase phosphatase a tRNA 6.3.5.6) @ (EC 1.2.1.12): NAD- propanoyl-CoA acetyl-CoA Kynureninase complex H protein] N 6 - urate catechol trp desulfurase protein] Methylmalonate- [NADPH] putative asp 6 Salicylate Salicylate Salicylate 3-phosphate synthase (EC 2.5.1.90) / [+ 6 isozymes] D-amino adenosylcob(III) : Riboflavin Precorrin-2 oxidase (EC 3.1.3.1) NAD kinase [acyl-carrier-protein] biotin-carboxyl carrier protein assembly protein] N -dihydrolipoyl-L-lysine [decarboxylating] Catechol 1,2- (EC 2.8.1.7) xylulose 5- III oxidase, aerobic adenylyltransferase Serine NAD(P) Glutamyl-tRNA(Gln) dependent glyceraldehyde- GlxC Glutamate (EC 3.7.1.3): aminomethyldihydrolipoyl-L-lysine hydroxylase hydroxylase Uricase Dimethylallyltransferase NAD + acid synthase (EC 1.3.1.76) / Glycine cleavage system H 3-methyl-2-oxobutanoate (EC 2.7.1.23) reductase semialdehyde Aspartate carbamate dioxygenase hydroxylase phosphate alamin-[corrinoid (EC 2.7.7.18): ubiquinol-8 hydroxymethyltransferase : Alkaline transhydrogenase: 3-hydroxyacyl-[acyl-carrier- amidotransferase 3-phosphate synthase [NADPH] G1RHH-1801 (EC 1.14.13.1) (EC 1.14.13.1) (EC (EC 2.5.1.1) / (2E,6E)- CDS oxidase protoporphyrinogen IX eubacterial/ Sirohydrochlorin a 7,8-dihydrofolate protein: Glycine cleavagea 5-methyltetrahydrofolate : NAD [+ 2 isozymes] dehydrogenase aminotransferase (EC 1.13.11.1) (EC 1.14.13.1) adenosyltranferase] Nicotinate-nucleotide (EC 2.1.2.1): Serine phosphatase G1RHH-1796 protein] dehydratase, a [biotin carboxyl-carrier protein]-L-lysine subunit B (EC (S)-3-amino-2- 3-carboxy-cis,cis-muconate HMS NADH synthase ferrochelatase system H protein CDS 3-methyl-2-oxobutanoate kinase (EC [+ 3 isozymes] (EC 1.2.1.27): large chain (EC : Salicylate : Salicylate 1.7.3.3): : Salicylate farnesyl diphosphate CDS eukaryotic (EC 3.1.3.1) methylpropanoate (EC 2.6.1.1) 3-hydroxyanthranilate : Catechol 1,2- 1-deoxy-D- Cob(I)alamin adenylyltransferase hydroxymethyltransferase (EC G1RHH-1797 FabA form (EC 4.2.1.59) Leucyl-tRNA 6.3.5.7): Aspartyl- Methylmalonate- hydroxylase hydroxylase Uricase synthase (EC 2.5.1.10) pyrophosphatase a thiocarboxy- (EC 4.99.1.4) / hydroxymethyltransferase 2.7.1.23) CDS a palmitoleoyl-[acp] [+ 9 isozymes] : Aspartate dioxygenase hydroxylase 1-palmitoyl- 1-stearoyl- 3-oxo-2-(cis-2'-pentenyl) a peptidoglycan (5E)-3-oxo- 966 adenosyltransferase CDS : 3-hydroxyacyl- Biotin--protein ligase tRNA(Asn) 13-DPG 2-hydroxymuconic a 1-acyl,2-lyso- ditrans,octacis- (5Z,8Z,11Z,14Z,17Z) a 2,3,4-saturated an N-terminal-L-methionyl- a guanine 3-hydroxyisovaleryl- xylulose 5- synthetase (EC (EC 1.14.13.1) (EC 1.14.13.1) (EC butan-1-ol an L-arginyl- a (3R,5Z)-3-hydrox / Geranylgeranyl (EC 3.6.1.22) [ThiS-Protein] 2-iminoacetate riboflavin nicotinate adenine Uroporphyrinogen- (EC 2.1.2.11): 3- semialdehyde glu aminotransferase (EC 1.13.11.1) (EC 1.14.13.1) a glutaryl-[acp] methyl ester a malonyl-[acp] an apo-[aryl-carrier protein] coenzyme A 2-methylbutanoate an acetyl-[acp] a malonyl-[acp] decanoate coenzyme A sn-glycerol a myristoyl-[acp] a stearoyl-[acp] sn-glycerol acetate -cyclopentane-1-(3R- dimer (meso- dodec-5- a protein (EC 2.5.1.17): [+ 6 isozymes] [acyl-carrier-protein] (EC 6.3.4.9, EC 6.3.4.10, amidotransferase CO 1.7.3.3) semialdehyde a tRNA precursor CTP ATP phosphatidylethanolamine undecaprenyldiphospho- -icosapentaenoate fatty acyl CoA L-threonyl-[protein] [tRNA Arg ] in 16S rRNA CoA phosphate dinucleotide 6.1.1.4): Leucyl- dehydrogenase 2 CDS CDS CDS tetradec-5-enoyl-[a pyrophosphate : NADH heme b biosynthesis III methyltransferase methyl-2-oxobutanoate EC 6.3.4.11, EC leu (EC 2.6.1.1) Aminomethyltransferase: cis,cis-muconate hydrolase Acetyl-coenzyme A Long-chain-fatty-acid-- Lysophospholipase N-acetyl-(N- Long-chain-fatty- 3-phosphate 3-phosphate Acetyl- hydroxyoctanoyl)-CoA diaminopimelate Methionine enoyl-CoA Alcohol dehydrogenase, Ribosomal RNA Cob(I)alamin Riboflavin kinase superpathway of heme tRNA synthetase Phosphoglycerate (2-carboxy-2,5-dihydro- CDS 3-oxoacyl-[acyl-carrier- Holo-[acyl-carrier protein] 3-oxoacyl-[acyl-carrier- 1-acyl-sn-glycerol- 1-acyl-sn-glycerol- Enoyl-CoA 3-ketoacyl- Arginine- Enoyl-CoA synthetase (EC 2.5.1.29) pyrophosphatase protoporphyrin IX NAD synthetase NAD synthetase II (anaerobic) (EC 2.1.1.107): NADP + [+ 5 isozymes] 2-amino-3- Aminomethyltransferase (S)-5- catechol synthetase (EC 6.2.1.1) CoA ligase (EC 6.2.1.3) tRNA (EC 3.1.1.5); acid--CoA ligase CoA:acetoacetyl- containing)D-alanyl-D-alanine zinc containing (EC small subunit adenosyltransferase b biosynthesis from 2-dehydropantoate a (2E)-dec-2-enoyl-[acp] 6.3.4.15): G1RHH-1824 kinase (EC 2.7.2.3) (EC 3.1.1.-): protein] synthase, synthase (EC 2.7.8.7) protein] synthase, acetylglucosaminyl) 3-phosphate 3-phosphate aminopeptidase tRNA-protein hydratase (EC 3.6.1.22) CDS (EC 2.7.1.26) / FMN Siroheme synthase / (EC 6.1.1.4) CDS oxaloacetate 5-oxofuran-2-yl)-acetate hydratase [isoleucine CoA thiolase : Octaprenyl diphosphate (EC 6.3.1.5) (EC 6.3.1.5) Methylenetetrahydrofolate Leu an L-glutaminyl- carboxymuconate- CDS hydroxyisourate : Acetyl-coenzyme A : Long-chain-fatty- nucleotidyltransferase Monoglyceride γ (EC 6.2.1.3): Long- CoA transferase, carboxypeptidase 1.1.1.1): Alcohol methyltransferase (EC uroporphyrinogen-III Biotin--protein ligase an L-leucyl-[tRNA ] : Phosphoglycerate propanoyl-CoA G1RHH-2670 KASI (EC 2.3.1.41): 3- : Holo-[acyl-carrier KASI (EC 2.3.1.41): 3- muramoyl-L-alanyl- - acyltransferase acyltransferase (EC 3.4.11.18) transferase [isoleucine Ferrochelatase, adenylyltransferase uroporphyrinogen-III Precorrin-2 oxidase palmitoleate Gln 4-carboxymuconolactone degradation] (EC 2.3.1.16) synthase (EC / Glutamine / Glutamine dehydrogenase Enoyl-[acyl-carrier-protein] [tRNA ] kinase (EC 2.7.2.3) CDS 6-semialdehyde [+ 2 isozymes] (2Z)-2- oxoacyl-[acyl-carrier- protein] synthase (EC synthetase (EC 6.2.1.1) oxoacyl-[acyl-carrier- acid--CoA ligase (EC (EC 2.7.7.21) (EC lipase (EC D-isoglutaminyl-N-(β- chain-fatty-acid- alpha subunit (EC (EC 3.4.16.4): D- : Methionine dehydrogenase, C (EC 2.1.1.52): degradation] NMN 2-[(2R,5Z)- protoheme ferro- (EC 2.7.7.2): (EC 6.3.4.9, EC 6.3.4.10, a tRNA Leu (EC 2.3.1.51): 1- (EC 2.3.1.51): 1- (EC 4.2.1.17) / 3- @ Acetyl-CoA (EC 2.3.2.8) thioredoxin ATP:Cob(I)alamin amidotransferase amidotransferase Uroporphyrinogen uroporphyrinogen-III 5,10- (NADP+) (EC 1.5.1.5) / decarboxylase (EC formate 2.7.7.25): tRNA 3.1.1.23); putative: -CoA ligase (EC 2.8.3.8): Acetyl- alanyl-D-alanine zinc containing (EC Ribosomal RNA 2-carboxy-4- reductase [NADH] (EC EC 6.3.4.11, EC hydroxypenta- protein] synthase, 4'-phosphopantetheinyl Acetyl-coenzyme A protein] synthase, Long-chain-fatty-acid-- D-asparaginyl)-L-lysyl-Cell division acyl-sn-glycerol- acyl-sn-glycerol- hydroxyacyl-CoA aminopeptidase : Arginine- (EC 4.2.1.17) / 3- (2E,6E)-farnesyl pathway adenosyltransferase lyase (EC 4.99.1.1) Riboflavin kinase III decarboxylase siroheme Uroporphyrinogen methylenetetrahydrofolateMethenyltetrahydrofolate 2-methyladeninyl adenosylcobamide 3-phospho-D-glycerate (+)-muconolactone 4.1.1.44): G1RHH-1791 nucleotidyltransferase carboxypeptidase acetyltransferase small subunit 5'-nucleotidase methylthiazol-5(2H chain of NAD chain of NAD 1.3.1.9): Enoyl-[acyl- 6.3.4.15): Biotin--protein 2,4-dienoate synthetase (EC 6.2.1.1) CoA ligase (EC 6.2.1.3) Lysophospholipase D-alanyl-D-alanine Long-chain-fatty- 3-phosphate 3-phosphate CoA:acetoacetyl- (EC 3.4.11.18) alcohol dehydrogenase, tRNA-protein hydroxyacyl-CoA diphosphate (EC 2.5.1.17): : Ferrochelatase, (EC 2.7.1.26) / FMN (EC 4.1.1.37): reductase (EC 1.5.1.20): 5,10- β-alanine (S)-2-oxo- 3-oxoacyl-[acyl-carrier- transferase entD 3-oxoacyl-[acyl-carrier- protein FtsI dehydrogenase (EC 2.3.1.9): 3- glutathione synthetase: NAD synthetase: NAD III decarboxylase cyclohydrolase (EC (R)-pantoate biosynthesis from adenosylcobinamide-GDP [+ 2 isozymes] : Long-chain-fatty- a tRNA (EC 2.7.7.21) (EC 3.1.1.5); CoA transferase, (EC dehydrogenase (EC 3.1.3.5): )-ylidene]ethyl an oxidized protoheme carrier-protein] reductase ligase (EC 6.3.4.9, EC Muconolactone 4-hydroxy- protein] synthase, (EC 2.7.8.-); Holo- : Acetyl-coenzyme A protein] synthase, [Peptidoglycan acid--CoA ligase 1-acyl-sn-glycerol- 1-acyl-sn-glycerol- (EC 1.1.1.35) / 3- Methionine ketoacyl-CoA zinc-containing: alcohol transferase 16S rRNA ATP:Cob(I)alamin Uroporphyrinogen (EC 4.1.1.37): methylenetetrahydrofolate3.5.4.9): G1RHH-2555 2,3-bisphosphoglycerate- 2,3-bisphosphoglycerate- containing a a 2,3,4-saturated a peptidoglycan Octaprenyl-diphosphate G1RHH-2543 biosynthesis phosphate FMN synthetase (EC synthetase (EC [+ 2 isozymes] Fatty Acid and Lipid Degradation synthetase (EC 6.2.1.1) acid--CoA ligase (EC (EC 6.2.1.3): Long- acetyl-CoA [+ 2 isozymes] dehydrogenase, (EC (guanine(966)-N(2) (EC 1.1.1.35) / thioredoxin adenosyltransferase ferro-lyase (EC III decarboxylase (EC reductase 2-methyladenine 5-hydroxybenzimidazolyl adenosylcobamide a [biotin carboxyl-carrier Valyl-tRNA androstenedione degradation β isomerase (EC (4,5-dihydro-5-oxofuran-2-yl)-acetate 4-carboxy-5- KASII (EC 2.3.1.179): [acyl-carrier protein] KASII (EC 2.3.1.179): Lysophospholipase synthetase] 3-phosphate 3-phosphate hydroxybutyryl-CoA aminopeptidase thiolase (EC synthase (EC 2.5.1.-) / 6.3.1.5) / Glutamine 6.3.1.5) / Glutamine Uroporphyrinogen independent independent fatty acid -oxidation I 3' CCA end fatty acid with D,D cross- an N-terminal 3-hydroxybutyryl- 5-nucleotidase Methylenetetrahydrofolate stearate 6 5.3.3.4),putative: ureidoimidazoline 3-oxoacyl-[acyl-carrier- synthase, alternative (EC 3-oxoacyl-[acyl-carrier- L2 (EC 3.1.1.5): (EC 2.4.1.129) chain-fatty-acid- epimerase (EC (EC 3.4.11.18) zinc-containing Arg )-methyltransferase a (5Z)-3-oxo- (EC coproporphyrinogen III III decarboxylase (EC a (6S)-5-formyltetrahydrofolate Pantoate--beta-alanine biosynthesis from adenosylcobinamide-GDP protein]-N -biotinyl-L-lysine synthetase (EC phosphoglycerate phosphoglycerate acyltransferase acyltransferase D-ala links (meso- 2.3.1.16) @ a tRNA Dimethylallyltransferase cys glu protoheme Riboflavin kinase 5,10- dehydrogenase a decanoyl-[acp] Beta-ketoadipate enol- 2-methylbutanoyl-CoA AMP diphosphate diphosphate AMP decanoyl-CoA -CoA ligase (EC arginyl-[protein] (EC 2.1.1.171) ## CoA epimerase tetradec-5-enoyl-[a SurE (EC NAD + ligase (EC 6.3.2.1): Nicotinate-nucleotide-- biosynthesis II 6.1.1.9): Valyl- G1RHH-1941 protein] synthase, 2.7.8.7): G1RHH-1017 protein] synthase, Lysophospholipase : Cell division (EC 2.3.1.51): (EC 2.3.1.51): 5.1.2.3): Enoyl-CoA : Methionine butan-1-al (EC 2.5.1.1) / (EC 2.7.1.26) / FMN thiamine diphosphate coproporphyrinogen III methylenetetrahydrofolate mutase (EC 5.4.2.1): 2,3- mutase (EC 5.4.2.1): 2,3- androst-4-ene-3,17-dione 4-chlorocatechol (5Z,8Z,11Z,14Z,17Z) diaminopimelate [+ 3 isozymes] (EC 5.1.2.3) 3.1.3.5): 5- Glutamate- Thioredoxin adenosylcobalamin Coproporphyrinogen (NADP+) (EC 1.5.1.5) / 5-formyltetrahydrofolate dimethylbenzimidazole NaMN (bacteria and plants) val a (3Z)-alk-3-enoyl-CoA lactone hydrolase (EC L2 (EC 3.1.1.5) CDS protein FtsI G1RHH-1918 G1RHH-1918 hydratase [isoleucine aminopeptidase (3E)-dec-3- SSU rRNA m(2) 2-(2-carboxy-4- adenylyltransferase biosynthesis I (E. coli) Pantoate--beta-alanine 5-hydroxybenzimidazole tRNA synthetase bisphosphoglycerate- bisphosphoglycerate- (4,5-dihydro-5- acyl-carrier protein a 3-oxopimeloyl-[acp] methyl ester a holo-[aryl-carrier protein] 3',5'-ADP an acetoacetyl-[acp] acyl-carrier protein 1-palmitoyl- 1-stearoyl-2- containing) acetyl-CoA Geranyltranstransferase reductase lipoate biosynthesis reductase (EC 1.5.1.20): 5,10-Methenyltetrahydrofolate cyclo-ligase (EC 6.3.3.2): 3-oxoacyl-[acyl-carrier- 3.1.1.24): Beta-ketoadipate sn-glycero-3- [Peptidoglycan -icosapentaenoyl-CoA G966: 16S rRNA : Enoyl-CoA nucleotidase -cysteine methylthiazol-5- III oxidase, oxygen- Coproporphyrinogen ligase (EC 6.3.2.1) phosphoribosyltransferase (EC 6.1.1.9) CDS oxofuran-2-yl)-acetate a carboxylate di-trans,octa-cis (EC 3.4.11.18) enoyl-CoA 2 (EC 2.7.7.2): independent independent a peptidoglycan acyl-carrier protein 2-myristoyl stearoyl-sn 3-oxo-2-(cis-2'-pentenyl)[+ 4 isozymes] an N - (farnesyldiphosphate (EC 1.8.1.9): and incorporation I 2-[(2R,5Z)- methylenetetrahydrofolatecyclohydrolase (EC 3.5.4.9) 5-formyltetrahydrofolate protein] synthase, a palmitoyl-[acp] a [biotin carboxyl-carrier-protein Val ∆ 3 ∆ 2 enol-lactone hydrolase phosphoethanolamine hydratase SurE (EC ligase (EC yl)ethyl phosphate independent III oxidase, aerobic (EC 2.4.2.21): G1RHH-2709 Nicotinate-nucleotide-- an L-valyl-[tRNA ] -cis- -trans-enoyl-CoA (S)-(+)-allantoin -undecaprenyl [+ 2 isozymes] acyl-carrier protein an N-terminal L- 966 synthase) (EC 2.5.1.10) Riboflavin kinase reductase 6 Beta-ketoadipate dimer (E. faeciums) phosphatidate -glycerol 3- -cyclopentane-1-(E- met methylguanine Thioredoxin 2-carboxy-4- : Methylenetetrahydrofolate cyclo-ligase (EC KASI (EC 2.3.1.41): 3- 3-oxoacyl- dimer]-N -biotinyl-L-lysine [isoleucine 3.1.3.5) CDS 6.3.2.2): (EC 1.3.99.22): (EC 1.3.3.3): dimethylbenzimidazole Val 2-phospho-D-glycerate isomerase: Enoyl-CoA Beta-ketoadipate enol- diphosphate threonyl-[protein] / Geranylgeranyl cytidylyl molybdenum (EC 2.7.1.26) / FMN HMP-PP methylthiazol-5(2H (R)-pantothenate oxoacyl-[acyl-carrier- a tRNA enol-lactone phosphate octa-2-enoyl)-CoA in 16S rRNA 1-(β-D Glutamate- reductase menaquinol-7 biosynthesis Coproporphyrinogen Coproporphyrinogen dehydrogenase 2-methyladenine phosphoribosyltransferase [acyl-carrier- Acetyl-coenzyme A androsta-1,4-diene-3,17-dione hydratase [isoleucine 3-chloro-cis lactone hydrolase (EC [+ 4 isozymes] pyrophosphate synthetase cofactor biosynthesis an octanoyl-[acp] a 5,10-methylenetetrahydrofolate a 5,10-methenyltetrahydrofolate hydrolase (EC (E)-2- ribofuranosyl) -cysteine (EC 1.8.1.9) III oxidase, )-ylidene]ethyl III oxidase, aerobic (EC 2.4.2.21): G1RHH-2709 protein] synthase, protein] ,cis-muconate 3.1.1.24): Beta-ketoadipate FAD thiamine-phosphate Pantothenate kinase adenosylcobinamide- ribotide phosphate acetyl-CoA carboxyl transferase Enolase (EC 4.2.1.11): 3.1.1.24): Beta- methylsalicylate degradation (EC 2.5.1.29): Octaprenyl- CDS MoO - all-trans- phosphate synthase, methylcrotonoyl- nicotinamide ligase (EC 2 1,4-dihydroxy- pyrophosphorylase, GDP 3-oxoacyl-[acyl-carrier- carboxyltransferase: alpha chain (EC 6.4.1.2) Enolase (EC 4.2.1.11) CDS a trans-2-enoyl-CoA enol-lactone hydrolase diphosphate synthase (EC Methylenetetrahydrofolate type III, CoaX-like (EC 5-hydroxybenzimidazole Enoyl-CoA hydratase ketoadipate CoA 6.3.2.2) CTP molybdopterin a [lipoyl-carrier heptaprenyl protoporphyrinogen IX protoporphyrinogen IX protein] synthase, KASI (EC γ-L-glutamyl- 6 2-naphthoate putative: G1RHH-1917 dehydrogenase 2.7.1.33): Pantothenate adenosylcobinamide-GDP ribotide phosphate Acetyl-coenzyme A : Acetyl-coenzyme A Alanyl-tRNA enol-lactone cofactorCTP:molybdopterin protein] N - diphosphate KASII (EC 2.3.1.179): 2.3.1.41): phosphoenolpyruvate Enoyl-CoA hydratase [isoleucine degradation] 3-oxoadipate 4-methylsalicylate 5-methylsalicylate Octaprenyl diphosphate (NADP+) (EC 1.5.1.5) / kinase type III, CoaX-like Cobalamin carboxyl transferase carboxyl transferase 9α-hydroxyandrosta- (2R)-2-chloro- hydrolase L-cysteine a reduced cytidylyltransferase: octanoyl-L-lysine Thiamin-phosphate 3-oxoacyl- synthetase (EC [isoleucine degradation] (EC 4.2.1.17) / 3- Salicylate Salicylate synthase 3-oxoacyl-[acyl-carrier- 6 synthase (EC 2.5.1.90) / thioredoxin Lipoate demethylmenaquinol-7 pyrophosphorylase menaquinol-6 biosynthesis Methenyltetrahydrofolate [+ 2 isozymes] 6.1.1.7): Alanyl- Pyruvate kinase (EC 1,4-diene-3,17-dione (EC 4.2.1.17) / 3- hydroxyacyl-CoA 2,5-dihydro-5- an O - 1-palmitoyl- lipid II (meso 3-oxo-2-(cis-2'-pentenyl) N-acetyl-β-D-glucosamine- an N-acetyl-β- a non-methylated Glutathione CTP:molybdopterin (R)-4'-phosphopantothenate Cobalamin synthase protein] synthase, [acyl-carrier- ala long-chain fatty acid- Beta-ketoadipate hydroxylase hydroxylase a 2-methyl branched DNA combined with exogenous DNA a [protein]- a cis- sn-glycero-3- 1-chloro-2,4- long chain chitin (2E,9Z)- Dimethylallyltransferase cyclohydrolase (EC (EC 2.7.8.26): oxofuran-2-acetate a malonyl-[acp] methyl ester succinyl-CoA acetoacetate butanoyl-CoA acetyl-CoA methylguanine 7,8-dihydropterin D-threo-isocitrate sn-glycerol diaminopimelate -cyclopentane-1-(3R- 1,6-anhydro-N- glutathione synthetase cytidylyltransferase synthase: (EC 2.5.1.3): (EC 2.7.8.26): protein] a [carboxyl-carrier protein dimer]- tRNA synthetase 2.7.1.40): Pyruvate CoA ligase: Long-chain- hydroxyacyl-CoA dehydrogenase (EC enol-lactone (EC 1.14.13.1) (EC 1.14.13.1) a malonyl-[acp] 2,3,4-saturated fatty acid ATP cob(II)inamide to form a recombinational junction phosphoethanolamine a tRNA precursor D-hexosaminide dinitrobenzene polyphosphate hexadecenoyl-CoA ribosomal (EC 2.5.1.1) / (2E,6E)- Ubiquinone/ G1RHH-2708 L-cysteine vaccenoyl-[acp] β Beta- Lipoate protoporphyrin IX Thiamin-phosphate protoporphyrin IX 3.5.4.9): G1RHH-2555 G1RHH-2708 6 (EC 6.1.1.7) CDS kinase (EC 2.7.1.40) CDS fatty-acid--CoA ligase (EC dehydrogenase (EC 1.1.1.35) / 3-hydroxybutyryl- Long-chain-fatty-acid-- Succinyl-CoA:3-ketoacid- Putative Holliday 3-ketoacyl-CoA thiolase in DNA Guanine deaminase Isocitrate dehydrogenase 3-phosphate containing) Glycerophosphoryl hydroxybutanoyl)-CoA acetyl- -D-muramate Beta- Glutathione Exopolyphosphatase protein L11 (EC 6.3.2.3): demethylmenaquinol-6 a 3-oxododecanoyl-[acp] synthase, N -carboxybiotinyl-L-lysine Ala hydrolase (EC : Salicylate : Salicylate 3-oxoacyl-[acyl-carrier- ADA regulatory 1-acyl-sn-glycerol- Cell division Ribonuclease D Beta- Enoyl-CoA farnesyl diphosphate Molybdopterin menaquinol-8 biosynthesis menaquinone an L-alanyl-[tRNA ] Enoyl-CoA hexosaminidase hexosaminidase Glutathione synthase pyrophosphorylase a 3-oxooctadecanoyl- 1.1.1.35) / 3-hydroxybutyryl- CoA epimerase (EC a (3R)-3-hydroxyacyl-CoA hydroxylase hydroxylase protein] synthase, CoA ligase (EC 6.2.1.3) ATP:Cob(I)alamin coenzyme A transferase junction resolvase (EC 2.3.1.16) @ Acetyl- (EC 3.5.4.3); [NADP] (EC 1.1.1.42); 3-phosphate diester S-transferase (EC 3.6.1.11): hydratase biosynthesis biosynthesis Ubiquinone/menaquinone Methylenetetrahydrofolate Coα-[α-(2- pyruvate 3-hydroxy-9,10-secoandrosta- coenzyme A a 2,3,4-saturated fatty acid long-chain fatty acid- 3.1.1.24): Beta- protein / protein FtsI hydratase [isoleucine related protein: hexosaminidase synthase (EC 2.5.1.10) CDS Ferrochelatase, thiamine (EC Ferrochelatase, [acp] a tRNA Ala CoA epimerase (EC 5.1.2.3): Enoyl-CoA : Long-chain-fatty- adenosyltransferase (EC subunit B (EC 2.8.3.5) YqgF: Putative Holliday CoA acetyltransferase (EC Hydroxydechloroatrazine Monomeric isocitrate phosphodiesterase (EC 3.2.1.52): domain Exopolyphosphatase (EC 3.2.1.52): synthetase biosynthesis dehydrogenase methyladenin-9-yl)]-Co Coα-[α-(5-hydroxybenzimidazolyl)]- 3-oxoacyl-[acyl-carrier 1,3,5(10)-triene-9,17-dione CoA ligase: Long-chain- Acyl-CoA dehydrogenase ketoadipate (EC 1.14.13.1) (EC 1.14.13.1) KASI (EC 2.3.1.41): 3- Methylated-DNA- acyltransferase [Peptidoglycan Ribonuclease (EC 3.2.1.52): [isoleucine / Geranylgeranyl protein MoeA / a [lipoyl-carrier methyltransferase protoheme ferro- protoheme ferro- acid--CoA ligase (EC 2.5.1.17): ATP:Cob(I)alamin : Succinyl-CoA:3- junction resolvase YqgF 2.3.1.9): 3-ketoacyl-CoA (EC 3.1.4.46): degradation] G1RHH-2604 G1RHH-2604 (EC 6.3.2.3) demethylmenaquinol-8 phosphate methyltransferase UbiE (NADP+) (EC 1.5.1.5) / β Coβ-adenosylcobamide 5'-phosphate protein] reductase (EC fatty-acid--CoA ligase (EC 5.1.2.3): Enoyl-CoA hydratase [isoleucine enol-lactone CDS CDS oxoacyl-[acyl-carrier- -protein-cysteine ethylaminohydrolase dehydrogenase [NADP] (EC 2.3.1.51): 1- D related protein: (EC 3.6.1.11) CDS degradation] CTP:molybdopterin 6 UbiE (EC 2.1.1.- -adenosylcobamide 3-oxoacyl- (EC 1.3.8.7): Acyl- 2-maleylacetate protoanemonin synthetase] (EC 4.2.1.17) / 3- G1RHH-2604 pyrophosphate protein] N -[(R) Ubiquinone/menaquinone lyase (EC 4.99.1.1) lyase (EC 4.99.1.1) hydratase [isoleucine adenosyltransferase (EC ketoacid-coenzyme A thiolase (EC 2.3.1.16) @ (EC 3.5.99.3): Guanine (EC 1.1.1.42): Isocitrate Glycerophosphoryl Beta N-acetyl- Glutathione Beta N-acetyl- CDS (EC 2.1.1.-): Ubiquinone/ Methenyltetrahydrofolate 5'-phosphate 1.1.1.100): G1RHH-1018 [acyl-carrier CoA dehydrogenase hydrolase protein] synthase, Long-chain-fatty-acid-- Crossover junction methyltransferase acyl-sn-glycerol- (EC 2.4.1.129) hydroxyacyl-CoA protein CDS Exopolyphosphatase (EC 4.2.1.17) / 3- synthetase (EC 2.5.1.29) cytidylyltransferase: -dihydrolipoyl]- ): Ubiquinone/ : Ferrochelatase, : Ferrochelatase, diester Beta N-acetyl- biosynthesis menaquinone biosynthesis cyclohydrolase (EC 3.5.4.9) [+ 4 isozymes] CoA ligase (EC 6.2.1.3) Cob(I)alamin Succinyl-CoA:3-ketoacid- endodeoxyribonuclease [+ 3 isozymes] (EC 2.1.1.63): ADA deaminase (EC 3.5.4.3); dehydrogenase [NADP] (EC 3-phosphate : Cell division glucosaminidase S-transferase (EC 3.6.1.11): glucosaminidase hydroxyacyl-CoA : Octaprenyl diphosphate Molybdopterin menaquinone protoheme protoheme [+ 3 isozymes] protein] (EC 1.3.8.7) CDS Enoyl-CoA hydratase 3-oxoacyl-[acyl-carrier- sn-glycerol dehydrogenase Ribonuclease D glucosaminidase glutathione L-lysine methyltransferase UbiE : Methylenetetrahydrofolate 3,4-dihydroxy-9,10-secoandrosta- 3-oxoadipate : Long-chain-fatty- adenosyltransferase (EC coenzyme A transferase: RuvC (EC 3.1.22.4): 3-oxohexanoyl-CoA Guanine deaminase (EC 3.2.1.52): domain (EC 3.2.1.52): dehydrogenase biosynthesis biosynthesis menaquinol-6 reductase [isoleucine degradation] protein] synthase, regulatory protein / Isocitrate dehydrogenase 1-acyl-sn-glycerol- protein FtsI ethanolamine (EC 1.1.1.35) / 3- (EC 3.1.26.3): Exopolyphosphatase a methylatedmeth synthase (EC (EC 2.1.1.-): Ubiquinone/ ferro-lyase (EC thiamine ferro-lyase (EC α α asn a 2,3,4-saturated fatty acyl CoA a 2,3,4-saturated (3S)-3-hydroxyacyl-CoA 2.5.1.17): Cob(I)alamin 3-phosphate (EC 3.2.1.52): Beta N-acetyl- protein Beta N-acetyl- dehydrogenase α α Co -[ -(5-hydroxybenzimidazolyl) a (3R)-3-hydroxydodecanoyl-[acp] (EC 1.1.1.100) 1,3,5(10)-triene-9,17-dione β 4-methylcatechol KASII (EC 2.3.1.179): acid--CoA ligase (EC Succinyl-CoA:3-ketoacid- Crossover junction (EC 3.5.4.3): Guanine [NADP] (EC 1.1.1.42): [Peptidoglycan hydroxybutyryl-CoA (EC 3.6.1.11) CDS (EC 1.1.1.35) / ribosomal cytidylyl protein MoeA / Co -[ -(2- oleate -oxidation (EC 4.2.1.17) / 3- [+ 2 isozymes] 3-phosphate Ribonuclease D Beta N-acetyl- glucosaminidase menaquinone biosynthesis protoheme diphosphate ]-Coβ-adenosylcobamide : G1RHH-1018 3-oxoadipate adenosyltransferase (EC coenzyme A Succinyl- endodeoxyribonuclease a [protein]-S- deaminase (EC 3.5.4.3) CDS Isocitrate dehydrogenase glucosaminidase [+ 7 isozymes] long chain 3-hydroxybutyryl- GGPP molybdenum menaquinol-7 protoheme methyladenin-7-yl)]-Co hydroxyacyl-CoA 3-oxoacyl-[acyl-carrier- a 2-methyl branched 2,3,4- a guanine in DNA acyltransferase lipid II (meso di-trans,octa-cis[+ 2 isozymes] epimerase (EC (EC 3.1.26.3) CDS glucosaminidase protein L11 menaquinol-8 a 10-formyltetrahydrofolate 3-hydroxyacyl-[acyl-carrier- an L-asparaginyl-[tRNA Asn ] AMP diphosphate triphosphate adenosylcobinamide CoA:3-ketoacid-coenzyme A resolution of recombinational junction methyl-L-cysteine (EC 2,4-dinitrophenyl- polyphosphate (EC CoA epimerase β [+ 3 isozymes] (2E,5Z)- dehydrogenase (EC protein] synthase, saturated fatty acyl-CoA 7,8-dihydrolumazine [NADP] (EC (EC 2.3.1.51): 5.1.2.3): Enoyl-CoA a nucleoside 5'- cofactor -adenosylcobamide formation of two intact strands diaminopimelate -undecaprenyl a tRNA (EC an N-acetyl-β- S-glutathione N-acetyl-D- protein] dehydratase, a (3R)-3- Asn 2-oxoglutarate monophosphate 1,6-anhydro-N- chitin (EC 5.1.2.3) tRNA (1E,2Z)-3-hydroxy-5,9,17- tetradecenoyl-CoA 1.1.1.35) / 3-hydroxybutyryl- acyl-carrier protein a 3-oxoglutaryl-[acp] methyl ester acetoacetyl-CoA succinate G1RHH-1918 containing) diphosphate hydratase [isoleucine GlcNAc an alcohol glucosamine FabZ form (EC 4.2.1.59) 1-palmitoyl-2- β D-hexosamine : Enoyl-CoA hydroxyoctadecanoyl- Macromolecule Modification trioxo-4,5:9,10-disecoandrosta- CoA epimerase (EC acetyl- -muramate acyl-carrier protein cis-vaccenoyl 3-oxo-2-(cis-2'-pentenyl)[+ 4 isozymes] hydratase : 3-hydroxyacyl- [acp] 1 (10),2-dien-4-oate 5.1.2.3): Enoyl-CoA Enoyl-CoA phosphatidate -cyclopentane-1-(E- [acyl-carrier-protein] 3-hydroxyacyl- [isoleucine tRNA processing hydratase hydratase [isoleucine buta-2-enoyl)-CoA Amino Acid Biosynthesis 3-hydroxyacyl-[acyl-carrier- [acyl-carrier- Aspartyl-tRNA [isoleucine (3E,5Z)-tetradeca- [+ 4 isozymes] 3-hydroxyacyl-CoA (S)-3-hydroxy-(9Z) protein] dehydratase, protein] synthetase a polycistronic degradation] 3,5-dienoyl-CoA 3-[(3aS,4S,7aS)-7a-methyl- dehydrogenase (EC -hexadecenoyl-CoA superpathway of L- FabA form (EC 4.2.1.59) dehydratase, (EC 6.1.1.12) tRNA precursor (2Z,4Z)-2-hydroxyhexa- (EC 4.2.1.17) / 3- superpathway of aromatic amino acid biosynthesis L-histidine biosynthesis superpathway of branched chain amino acid biosynthesis superpathway of L-methionine superpathway of L-lysine, L-threonine and L-methionine biosynthesis I superpathway L-asparagine biosynthesis III (tRNA-dependent) superpathway of L-methionine biosynthesis (by sulfhydrylation) 1.1.1.35): 3-hydroxyacyl- isoleucine biosynthesis I L-arginine biosynthesis I (via L-ornithine) superpathway of L-homoserine : 3-hydroxyacyl- FabZ form @ Aspartyl- 2,4-dienoate 1,5-dioxo-octahydro-1H biosynthesis (transsulfuration) of L-threonine hydroxyacyl-CoA 3-ketoacyl-CoA thiolase CoA dehydrogenase (EC and L-methionine biosynthesis [acyl-carrier-protein] (EC 4.2.1.59): -inden-4-yl]propanoate 4 tRNA(Asn) an O - 3-oxo-2-(cis-2'-pentenyl) 527 biosynthesis dehydrogenase a 2,3,4-saturated fatty acyl CoA (EC 2.3.1.16) @ Acetyl- a 2,3,4-saturated 3-oxoacyl-CoA a 3-methyl-branched ditrans,octacis- 3-methoxy-4- 3-oxo-(5Z)- a [glutamine- a guanine (2E,7Z)- oxaloacetate D-erythrose 4-phosphate PRPP pyruvate oxaloacetate 3-hydroxyacyl- Ribonuclease E Ribonuclease E (3E,5Z)- succinyl-CoA a 3-oxo acid apo-[propionyl-CoA:carbon- 3-oxo-palmitoyl-CoA a [protein]- [DNA] (6E)-8-oxogeraniol an L-phenylalanyl- an N-terminal an L-arginyl- an N-terminal L- an aldehyde citrate synthetase methylthymine thr L-homoserine asp glu asp (EC 1.1.1.35) / CoA acetyltransferase (EC 2,3,4-saturated fatty acid biotin L-allo-threonine undecaprenyldiphospho- Phe hydroxyphenylglycolaldehyde -cyclopentane-1-(3R- Arg tetradecenoyl-CoA hexadecenoyl-CoA a butanoyl-[ac oxaloacetate a (2E)-dodec-2-enoyl-[acp] [acyl-carrier- (EC 3.1.26.12) (EC 3.1.26.12) tetradecadienoate ATP cob(II)alamin dioxide ligase (ADP-forming)] L-cysteine [tRNA ] L-lysyl-[protein] [tRNA ] glutamyl-[protein] synthetase]- ATP in 16S rRNA Aspartate asp oxaloacetate (EC 6.1.1.23): 3-hydroxybutyryl- Succinyl-CoA:3-ketoacid- Long-chain-fatty-acid-- 3-ketoacyl-CoA thiolase in DNA Exodeoxyribonuclease Alcohol dehydrogenase, N-acetyl-(N- Aldehyde hydroxyhexanoyl)-CoA alcohol dehydrogenase, Aconitate hydratase rRNA small subunit 2-keto-3-deoxy-D- ATP Aspartate 2.3.1.9): 3-ketoacyl-CoA Biotin--protein ligase Low-specificity L- ADA regulatory Leucyl/ Arginine- 3-ketoacyl- L-tyrosine Enoyl-CoA aminotransferase Acetolactate Aspartate protein] Aspartyl-tRNA : Ribonuclease : Ribonuclease Cob(I)alamin Enoyl-CoA Glutamate- L-serine Aspartate Aspartokinase Glutamate N- Aspartyl- (S)-4-hydroxy-2-oxohexanoate 3-[(3aS,4S,7aS)-7a-methyl- CoA epimerase thiolase (EC 2.3.1.16) @ coenzyme A transferase CoA ligase (EC 6.2.1.3) (EC 6.3.4.9, EC 6.3.4.10, threonine aldolase (EC (EC 2.3.1.16) @ Acetyl- III (EC 3.1.11.2): zinc containing (EC 1.1.1.1) acetylglucosaminyl) dehydrogenase (EC zinc-containing: alcohol CoA thiolase (EC 4.2.1.3): 7-methylguanosine hydratase (EC 2.6.1.1) glycine arabino-heptulosonate- phosphoribosyltransferase synthase Aspartokinase aminotransferase (EC Enoyl-[acyl-carrier-protein] asp E (EC E (EC protein / phenylalanyl- hydratase [isoleucine tRNA-protein ammonia ligase aminotransferase Homoserine O- (EC 2.7.2.4): aminotransferase tRNA 3-hydroxyacyl- synthetase 1,5-dioxo-octahydro-1H- (EC 5.1.2.3) subunit B (EC 2.8.3.5) : Long-chain-fatty- adenosyltransferase (EC CoA acetyltransferase (EC Exodeoxyribonuclease : Alcohol dehydrogenase, muramoyl-L-alanyl-γ-D- 1.2.1.3): Aldehyde dehydrogenase, (EC 2.3.1.16) Aconitate hydratase (m7G) biosynthesis IV 7- phosphate synthase (EC 2.4.2.17): ATP large subunit dehydratase, acetyltransferase 2.6.1.1): Aspartate sulfate reductase [NADH] (EC 3.1.26.12) CDS 3.1.26.12) CDS [+ 3 isozymes] EC 6.3.4.11, EC 4.1.2.48): Low-specificity Methylated-DNA- tRNA--protein degradation] transferase adenylyltransferase [isoleucine : Aspartate (EC 2.6.1.1) succinyltransferase (EC 2.7.2.4): (EC 2.6.1.1) (EC 6.1.1.12) @ inden-4-yl]propanoyl-CoA : Enoyl-CoA : Succinyl-CoA:3- acid--CoA ligase (EC 2.5.1.17): Cob(I)alamin 2.3.1.9): 3-ketoacyl-CoA III (EC 3.1.11.2) zinc containing (EC isoglutaminyl-L-lysyl- dehydrogenase zinc-containing @ Acetyl-CoA (EC 4.2.1.3) CDS methyltransferase II (EC 2.5.1.54): 2-keto- phosphoribosyltransferase (EC beta subunit Aspartokinase (EC 2.3.1.35) / N- synthetase aminotransferase 1.3.1.9): Enoyl-[acyl- [acyl-carrier- 6.3.4.15): G1RHH-1824 L-threonine aldolase (EC -protein-cysteine transferase (EC 2.3.2.8) degradation] aminotransferase (EC 2.2.1.6): Aspartokinase : Aspartate an L-aspartyl-[tRNA asp ] adenosyltransferase (EC Cell division (EC 4.2.1.17) / 3- (EC 2.7.7.42) (EC 4.3.1.17) : Aspartate (EC 2.3.1.46): (EC 2.7.2.4) CDS acetylglutamate (EC 6.1.1.12) protein] a tRNA precursor a tRNA precursor hydratase ketoacid-coenzyme A Long-chain-fatty-acid-- thiolase (EC 2.3.1.16) @ Exodeoxyribonuclease alcohol dehydrogenase, (glycyl) -D-alanyl-D-alanine (EC 1.2.1.3) CDS Alcohol dehydrogenase, acetyltransferase Aconitate hydratase GidB: rRNA (EC 4.2.1.17) / 3- (EC 2.6.1.1) thr 3-deoxy-D-arabino- ATP Acetolactate (EC 2.7.2.4) CDS (EC 2.6.1.1) Sulfate carrier-protein] reductase Biotin--protein ligase Serine methyltransferase 5 protein FtsI (EC 2.3.2.6) hydroxyacyl-CoA : Arginine- : Glutamate- aminotransferase asp [isoleucine heptulosonate-7- / L-serine aminotransferase G1RHH-1902 cys synthase (EC @ Aspartyl- adenylyltransferase dehydratase, tRNA with a 5' with a 5' Succinyl-CoA:3-ketoacid- CoA ligase (EC 6.2.1.3) ATP:Cob(I)alamin [+ 3 isozymes] (EC 2.1.1.63): ADA III (EC 3.1.11.2): zinc-containing: alcohol : Leucyl/ [+ 5 isozymes] zinc containing (EC (EC 2.3.1.9): 3- 2 (EC 4.2.1.3): small subunit 7- hydroxyacyl-CoA Low-specificity phosphoribosyltransferase synthase L-aspartyl- (EC 2.6.1.1) [+ 5 isozymes] [+ 2 isozymes] (EC 6.3.4.9, EC 6.3.4.10, hydroxymethyltransferase [Peptidoglycan dehydrogenase tRNA-protein a [glutamineammonia ligase [+ 5 isozymes] (EC 2.6.1.1) tRNA(Asn) FabA form extension and extension and a 5-hydroxy-3-[(3aS,4S,5R,7aS)- adenosyltransferase (EC Exodeoxyribonuclease vanillyl mandelate 1.1.1.1): Alcohol ketoacyl-CoA methylguanosine dehydrogenase large dehydratase, 4-phosphate 2.3.1.1): Glutamate L-aspartyl- (EC 2.7.7.4) / 1-propanal pyruvate [+ 4 isozymes] acetyl-CoA coenzyme A transferase: : Long-chain-fatty- EC 6.3.4.11, EC (EC 2.1.2.1): Serine myristoyl-CoA acetyl-CoA regulatory protein / dehydrogenase, synthetase] phenylalanyl- (EC 1.1.1.35) / 3- transferase synthetase]-O Aconitate hydratase asp L-threonine 3-deoxy-D-arabino- regulatory subunit [+ 5 isozymes] thiolase (EC (m7G) alpha subunit [+ 5 isozymes] O-succinyl-L- N-acetyltransferase 4-phosphate synthetase Adenylylsulfate kinase (EC 4.2.1.59): a long 3' trailer short 3' extension 7a-methyl-1,5-dioxo-octahydro- Succinyl-CoA:3-ketoacid- acid--CoA ligase (EC 2.5.1.17): ATP:Cob(I)alamin III (EC 3.1.11.2) zinc-containing tRNA--protein dehydrogenase, 4 2 (EC 4.2.1.3) CDS 7 (EC 1.1.1.35) / (EC 2.4.2.17): ATP subunit (EC asp a dodecanoyl-[acp] 6.3.4.15): Biotin--protein hydroxymethyltransferase (EC [+ 2 isozymes] (EC 2.4.1.129) hydroxybutyryl-CoA (EC -(5'-adenylyl) an N - a 3-oxohexanoyl-[a aldolase (EC heptulosonate 7-phosphate a 2'- an N-terminal 2.3.1.16) @ (EC 4.3.1.17): homoserine Aspartate- (EC asp (EC 6.1.1.23) (EC 2.7.1.25): Sulfate 3-hydroxyacyl- 1H-inden-4-yl]propanoyl-CoA coenzyme A Succinyl- adenosyltransferase (EC a [protein]-S- Phe L-phenylalanyl- zinc containing (EC 527 3-hydroxybutyryl- 4.1.2.48): Low- phosphoribosyltransferase (S)-3-hydroxy-(5Z) a 3-methyl-branched 2,3,4- ligase (EC 6.3.4.9, EC acetaldehyde gly a thymine in DNA deoxyribonucleoside [DNA] (6E)-8-oxogeranial : Cell division a tRNA epimerase (EC L-arginiyl-L- a tRNA Arg -L-tyrosine D-threo-isocitrate methylguanine Aspartokinase Acetolactate Aspartate- : Aspartyl- [acyl-carrier- Carboxylate Degradation diphosphate AMP triphosphate adenosylcobalamin CoA epimerase 3-dehydroquinate G1RHH-2694 asp semialdehyde Aspartokinase (EC adenylyltransferase Tyrosyl-tRNA -tetradecenoyl-CoA CoA:3-ketoacid-coenzyme A saturated fatty acyl-CoA [propionyl-CoA:carbon- methyl-L-cysteine protein FtsI L-lysyl-[protein] 5.1.2.3): Enoyl-CoA an alcohol [+ 3 isozymes] in 16S rRNA (EC 2.7.2.4): specificity regulatory N-acetyl-L- semialdehyde Aspartokinase 5'-monophosphate glutamyl-[protein] (3Z)-dodec- synthase (EC 4.2.3.4) synthase: dehydrogenase tRNA 2.7.2.4): Aspartokinase (EC 2.7.7.4) / 3-oxoacyl-[acyl-carrier- protein] synthetase (EC dioxide ligase (ADP-forming)] hydratase [isoleucine (EC 5.1.2.3) L-threonine [+ 3 isozymes] O-acetylhomoserine glutamate Ribonuclease a 2,3,4-saturated 3-oxoacyl-CoA succinate di-trans,octa-cis[Peptidoglycan acetyl-CoA Aspartokinase : 3-dehydroquinate β Acetolactate Aspartokinase (EC 1.2.1.11) dehydrogenase (EC 2.7.2.4): synthetase 6.1.1.1): Tyrosyl- propanoyl-CoA propanoyl CoA 3-enoyl-CoA : Enoyl-CoA aldolase (EC 1-(5-phospho- -D-ribosyl)-ATP (2Z)-2-aminobut- (EC 2.7.2.4) CDS protein] synthase, a (2E)-octadec- Ribonuclease (2E)-3-[(3aS,4S,5R,7aS) a peptidoglycan (EC 2.7.2.4) CDS synthase (EC 2.7.2.4): sulfhydrylase (EC 1.2.1.11) Aspartokinase (EC APS tyr P protein pyruvate fermentation pyruvate fermentation propanoyl-CoA pyruvate decarboxylation to acetyl CoA glycolate and superpathway of acetate utilization and formation [+-undecaprenyl 2 isozymes] 3-oxo-2-(cis-2'-pentenyl)[+ 4 isozymes] synthase (EC 4.2.3.4) : Aspartate- Acetylglutamate KASI (EC 2.3.1.41): 3- tRNA synthetase D related -5-hydroxy-7a-methyl-1- degradation I dimer (S. aureus) hydratase gly 2-enoate (EC 2.5.1.49) / O- : Aspartate- (EC 2.7.2.4) CDS laurate 2-enoyl-[acp] component to acetate IV to acetate II degradation II glyoxylate diphosphate -cyclopentane-1-(E- Phosphoribosyl-ATP large Aspartokinase semialdehyde kinase (EC 6.1.1.12) @ oxoacyl-[acyl-carrier- (EC 6.1.1.1) CDS [isoleucine L-aspartyl- 3-dehydroquinate L-aspartyl-4-phosphate Tyr protein: oxo-octahydro-1H-inden- Dihydrolipoamide pyrophosphatase subunit (EC (EC 2.7.2.4) CDS succinylhomoserine semialdehyde Sulfate an L-tyrosyl-[tRNA ] (EC 3.1.26.5): degradation II hexa-2-enoyl)-CoA synthase (EC 4.2.3.4) # dehydrogenase 2.7.2.8): L-aspartyl- protein] synthase, Enoyl-[acyl- cis-vaccenate Ribonuclease 4-yl]prop-2-enoyl-CoA propanoyl-CoA acetate Acetyl-coenzyme A 4-phosphate sulfhydrylase dehydrogenase an L-aspartyl- adenylyltransferase Long-chain-fatty-acid-- Ribonuclease Ribonuclease pyruvate pyruvate propanoyl-CoA acetyltransferase [+ 4 isozymes] (EC 3.6.1.31): Acetolactate (EC Acetylglutamate carrier- biosynthesis a tRNA Tyr Propionyl-CoA glycolate synthetase (EC 6.2.1.1) (S)-3-hydroxy-(7Z) AroB: 3-dehydroquinate L-aspartyl- 4-phosphate [tRNA Asn ] Aspartate-semialdehyde 3-oxoacyl-[acyl-carrier- D (EC 3.1.26.3)D related P protein Dihydrolipoamide component of pyruvate Phosphoribosyl-ATP synthase (EC 2.5.1.48): kinase (EC (EC (EC 2.7.7.4) / CoA ligase (EC 6.2.1.3) protein] Acetate kinase (EC Aspartate- synthase (EC 4.2.3.4) # 4-phosphate protein CDS carboxylase: dehydrogenase: Glycolate : Acetyl-coenzyme A -hexadecenoyl-CoA pyrophosphatase (EC small 2-iminobutanoate G1RHH-2713 Aspartate- dehydrogenase (EC Adenylylsulfate kinase protein] synthase, : Long-chain-fatty- : Ribonuclease component (EC acetyltransferase semialdehyde 2.7.2.8) CDS Aspartate- Aspartate- Aspartyl-tRNA(Asn) reductase a palmitoleoyl-[acp] Propionyl-CoA a [pyruvate dehydrogenase dehydrogenase (EC 2.7.2.1): Acetate kinase synthetase (EC 6.2.1.1) semialdehyde 1.2.1.11): Aspartate- (EC 2.7.1.25): Sulfate KASII (EC 2.3.1.179): acid--CoA ligase (EC D (EC 3-[(3aS,4S,5R,7aS)-5- component of pyruvate 6 Pyruvate dehydrogenase dehydrogenase 3-dehydroquinate subunit (EC O-acetylhomoserine amidotransferase [NADH] (EC Ribonuclease carboxylase acryloyl-CoA E2 protein] N -lipoyl-L-lysine (EC 2.7.2.1) CDS 1-(5-phospho-β-D-ribosyl)-AMP Aspartate- dehydrogenase N-acetylglutamyl- semialdehyde semialdehyde semialdehyde 3-oxoacyl-[acyl-carrier- 3-oxoacyl- 3.1.26.3) CDS dehydrogenase E1 component alpha 1.1.99.14): Glycolate Acetyl-coenzyme A adenylyltransferase Long-chain-fatty-acid-- 1.3.1.9): Enoyl- D (EC 3.1.26.3) hydroxy-7a-methyl-1-oxo- a (2R)-2-hydroxy even 1-(oleoyl)-sn-glycero-3- α-D-mannose (3R)-3- (2E,11Z)- (EC 1.2.1.11) semialdehyde sulfhydrylase phosphate dehydrogenase dehydrogenase subunit: Aspartyl- Tryptophanyl- carboxyl dehydrogenase (EC Acetate kinase (EC synthetase (EC 6.2.1.1) (15Z)-tetracosenoate a 2,3,4-saturated 1,2-diacyl- α-linolenate octanoyl-CoA acetyl-CoA indole-3-glycol 2-phenylethanol L-arabinitol a [protein] (L-serine/L- a sulfurated a nucleoside an L-arginyl- an N-terminal L- (S)-malyl-CoA NADH carbonic acid (EC 1.2.1.11) dehydrogenase (EC (EC 2.7.7.4) / protein] synthase, [acyl-carrier- octahydro-1H-inden-4-yl]- complex (EC 2.3.1.12) Pyruvate dehydrogenase numbered straight chain CTP glyoxylate ser hydrogen cyanide a ribonucleic acid : Aspartate- 3-dehydroquinate (S)-2-acetolactate (EC 2.5.1.49) / O- tRNA(Asn) CoA ligase (EC 6.2.1.3) [acyl-carrier- Ribonuclease: Ribonuclease Propionyl-CoA acetyl-CoA formate phosphoethanolamine 1-phosphate Arg hydroxyoctadecanoyl-CoA octadecenoyl-CoA a stearoyl-[a dehydrogenase (EC 1.2.1.11) (EC 1.2.1.11) tRNA synthetase Dihydrolipoamide 1.1.99.14), Glycolate 2.7.2.1): Acetate kinase : Acetyl-coenzyme A sn-glycerol 3-phosphate threonine) phosphate [sulfur carrier] triphosphate [tRNA ] aspartyl-[protein] Phosphoribosyl- : Aspartate- gln : Long-chain-fatty- protein] Ribonuclease a tRNA precursor 3-hydroxypropanoyl-CoA : Dihydrolipoamide E1 component beta 2,3,4-saturated fatty acid Long-chain-fatty-acid-- Long-chain-fatty-acid-- 3-ketoacyl-CoA thiolase Alcohol dehydrogenase, Alcohol dehydrogenase, Alcohol dehydrogenase, Lysophospholipase Phosphomannomutase L-malyl-CoA/beta- NADH Acetoacetyl- carbonic anhydrase, semialdehyde dehydratase II succinylhomoserine N-acetyl- : Aspartate- amidotransferase Aspartate-semialdehyde protein] D related D (EC carboxylase (EC 2.7.2.1) CDS long-chain fatty Phosphatidate Serine--glyoxylate Protein phosphatase Rhodanese DNA- Arginine- Enoyl-CoA AMP cyclohydrolase Ketol-acid 2-oxobutanoate (EC 1.2.1.11) semialdehyde : Aspartate- PAPS synthase, (EC 6.1.1.2): with a short acetyltransferase acetyltransferase Dihydrolipoamide dehydrogenase (EC synthetase (EC 6.2.1.1) CoA ligase (EC 6.2.1.3) (EC 2.3.1.16) @ Acetyl- zinc containing (EC 1.1.1.1) zinc containing (EC 1.1.1.1) (EC 5.4.2.8): family 3: carbonic (EC 4.2.1.10): 3- gamma- dehydrogenase (EC acid--CoA ligase (EC reductase protein: 3.1.26.3) CDS PH (EC Enoyl-CoA (S)-methylmalonyl- Phosphate pyruvate cytidylyltransferase (EC CoA ligase (EC 6.2.1.3) aminotransferase (EC zinc containing (EC 1.1.1.1) L2 (EC 3.1.1.5): ImpM: Protein domain methylmalyl-CoA pyrophosphatase CoA reductase hydratase dehydrogenase (EC 3.5.4.19): : Aspartate- sulfhydrylase semialdehyde semialdehyde Aspartyl-tRNA(Asn) a 3-oxotetradecanoyl-[acp] KASII (EC Tryptophanyl- 3-hydroxypropanoyl- component of pyruvate acetyltransferase 1.1.99.14), Glycolate acid-CoA ligase: directed RNA tRNA-protein dehydroquinate reductoisomerase dehydrogenase 1.2.1.11): Aspartate- Trp 2.7.7.56): 3' extension hydratase [isoleucine CoA acetyltransferase acetyl-CoA acetyl phosphate acetyl-CoA : Long-chain-fatty- : Long-chain-fatty- CoA acetyltransferase (EC : Alcohol dehydrogenase, : Alcohol dehydrogenase, : Alcohol dehydrogenase, Lysophospholipase Phosphomannomutase lyase (EC 4.1.3.- (EC 3.6.1.22) (EC 1.1.1.36) anhydrase, (EC (EC 2.5.1.48): O- glutamyl- dehydrogenase amidotransferase Imidazole a tRNA Ribonuclease CoA Long-chain-fatty- 2.7.7.41): Phosphatidate 2.6.1.45): Serine--glyoxylate phosphatase ImpM CDS protein: polymerase transferase [isoleucine G1RHH-1890 (EC 1.1.1.86) Acetolactate semialdehyde (EC dehydrogenase Phosphoadenylyl- lauroyl-CoA [+ 2 isozymes] 2.3.1.179): tRNA synthetase dehydrogenase dehydrogenase zinc containing (EC dehydratase II (EC phosphate glycerol semialdehyde D related Ribonuclease degradation] (EC 2.3.1.8) Dihydrolipoamide acid--CoA ligase (EC cytidylyltransferase (EC acid--CoA ligase (EC aminotransferase (EC 2.3.1.9): 3-ketoacyl-CoA zinc containing (EC zinc containing (EC L2 (EC 3.1.1.5) CDS G1RHH-2291 (EC 5.4.2.8) CDS ): L-malyl-CoA/ : NADH of ethylmalonyl- family 3 CDS degradation] β acetylhomoserine (EC Methylmalonyl- complex (EC 2.3.1.12) acid--CoA ligase (EC Serine/threonine beta: DNA- (EC 2.3.2.8) Aspartate- 1-(5-phospho- -D-ribosyl)- : Ketol-acid synthase dehydrogenase (EC Aspartyl-tRNA(Asn) sulfate reductase 3-oxoacyl-[acyl-carrier 3-oxoacyl- (EC 6.1.1.2) PH (EC Phosphate 3-hydroxyisobutyryl- (EC 1.1.99.14), thiolase (EC 2.3.1.16) @ dehydrogenase (EC Trp (EC 4.2.1.17) / 3- : Phosphate acetyltransferase Long-chain-fatty-acid-- Long-chain-fatty-acid-- Alcohol dehydrogenase Alcohol dehydrogenase alcohol dehydrogenase, Phosphomannomutase beta-methylmalyl- pyrophosphatase CoA pathway: Carbonic anhydrase (EC 4.2.1.17) / 3- 5-[(5-phosphoribosylamino) large subunit (EC sulfhydrylase (EC L-aspartate 4- reductase phosphate [thioredoxin] (EC 1.8.4.8) protein] reductase (EC a stearoyl-[acp] an L-tryptophanyl-[tRNA ] protein CDS CoA epimerase acetyltransferase (EC CoA hydrolase : Dihydrolipoamide long-chain fatty Phosphatidate Serine--glyoxylate Lysophospholipase phosphatase PPP [+ 2 isozymes] directed RNA : Arginine- semialdehyde 3-dehydroshikimate reductoisomerase Aspartate- amidotransferase [acyl-carrier- 2.7.7.56) CDS hydroxyacyl-CoA acetyltransferase [+ 3 isozymes] zinc-containing: alcohol an unsulfurated CoA lyase (EC (EC 3.6.1.22) CDS Acetoacetyl- semialdehyde (EC 1.2.1.38) L-aspartate 4- synthase (EC 5.1.99.1); acetyltransferase component of pyruvate Glycolate CoA ligase (EC 6.2.1.3) cytidylyltransferase (EC CoA ligase (EC 6.2.1.3) aminotransferase (EC (EC 1.1.1.1): Alcohol (EC 1.1.1.1): Alcohol (EC 3.1.1.5); (EC 3.1.3.16): thiocyanate polymerase (EC 5.4.2.8): tRNA-protein (EC 4.2.1.1): hydroxyacyl-CoA dehydrogenase methylideneamino]imidazole- (EC 1.1.1.86) (EC 2.2.1.6): semialdehyde subunit B (EC / Adenylyl-sulfate 1.1.1.100): G1RHH-1018 protein] trp Ribonuclease 2.3.1.8): Phosphate (EC 3.1.2.4): acid-CoA ligase: reduced β- Aspartate- semialdehyde L-aspartate 4-semialdehyde dehydrogenase (EC 2.3.1.8) dehydrogenase dehydrogenase (EC 3-oxodecanoyl-CoA dehydrogenase, [sulfur carrier] Phosphomannomutase CoA reductase dehydrogenase 4-carboxamide : N-acetyl- cyclase D related Ethylmalonyl- G1RHH-2634 Long-chain-fatty- : Long-chain-fatty- 2.7.7.41): Phosphatidate : Long-chain-fatty- 2.6.1.45): Serine--glyoxylate dehydrogenase dehydrogenase Monoglyceride Serine/threonine beta' transferase Malyl-CoA lyase Carbonic anhydrase (EC 1.2.1.11) shikimate Shikimate 5- (2R)-2,3- Acetolactate semialdehyde 4-hydroxy- dehydrogenase 6.3.5.6) @ reductase [thioredoxin] [+ 3 isozymes] synthase, acetyltransferase [+ 2 isozymes] Phosphate zinc-containing nicotinamide D- AMP (EC 1.1.1.36) of L-cystathionine gamma- subunit (EC 1.1.1.35) / 3- CoA epimerase: complex (EC 2.3.1.12) 1.1.99.14), subunit acid--CoA ligase (EC acid--CoA ligase (EC (EC 1.1.1.1) CDS (EC 1.1.1.1) CDS lipase (EC (EC 5.4.2.8) CDS (EC 4.1.3.24): (EC 4.2.1.1) CDS (EC 1.1.1.35) / an (11Z)-3-oxooctadec- Phosphate Dihydrolipoamide cytidylyltransferase (EC aminotransferase (EC phosphatase PPP (EC subunit DNA- (EC : Aspartate- dehydrogenase: dehydrogenase I alpha Phosphoribosylformimino- dihydroxy-3- synthase dehydrogenase tetrahydrodipicolinate Homoserine (EC 1.2.1.11) Glutamyl-tRNA(Gln) Homoserine (EC 1.8.4.10): protein: (EC 2.3.1.8) acetyltransferase (EC acid--CoA ligase (EC D-mannopyranose an N-terminal ribonucleotide a 3-oxoicosanoyl-[ glutamyl- (EC 4.1.3.-) Ribonuclease hydroxybutyryl-CoA Methylmalonyl- 3-hydroxypropanoate : Dihydrolipoamide GlcD: Glycolate a (R)-2-hydroxy even L-arabinopyranose 3.1.1.23); putative: Malyl-CoA lyase 3-hydroxybutyryl- Shikimate 5- (EC 1.1.1.25): Shikimate 5-aminoimidazole large dehydrogenase Phosphoadenylyl- a (3R)-3-hydroxytetradecanoyl-[acp] 11-enoyl-[acp] Ribonuclease acetyltransferase acetyltransferase a CDP-2,3,4-saturated-diacylglycerol indole-3-glycol aldehyde phenylacetaldehyde a [protein] Ser/Thr directed RNA Arg 3-oxooctadecanoyl-CoA CO H O semialdehyde methylbutanoate (EC 1.2.1.11) synthase (EC 4.3.3.7) : Aspartate- amidotransferase dehydrogenase (EC long-chain Phosphate 2.3.1.8): Phosphate AMP diphosphate (Z)-15-tetracosenoyl-CoA AMP diphosphate α-linolenoyl-CoA gly hydroxypyruvate 6-phosphate L-arginiyl-L- a tRNA 2 2 phosphate : Imidazole stearate PH (EC epimerase (EC CoA epimerase (EC 2.3.1.8) component of pyruvateacetyltransferase dehydrogenase diphosphate AMP numbered straight chain Lysophospholipase polymerase (EC 4.1.3.24) CDS CoA epimerase dehydrogenase 5-dehydrogenase carboxamide ribotide subunit (EC (EC 1.1.1.3): sulfate reductase fatty acid 3-oxoacyl- Threonyl-tRNA D related a [pyruvate dehydrogenase E2 a [pyruvate dehydrogenase E2 protein] acetyltransferase aspartyl-[protein] dehydrogenase Dihydroxy-acid : Aspartate- L-cystathione : G1RHH-2280 N-acetyl-L- semialdehyde subunit B (EC glycerol 1.1.1.3): Homoserine 2.7.7.56): 5.1.2.3): Enoyl-CoA acetyltransferase (EC (EC 1.1.99.14), 2,3,4-saturated fatty acyl CoA (EC 3.1.1.5); (EC 5.1.2.3) 3-hydroxyacyl-[acyl-carrier- (EC 5.1.99.1); : Phosphate 6 dehydrogenase 6 beta subunit acetyl-CoA glyoxylate (EC I alpha (EC I alpha (EC isomerase (EC 5.3.1.16): semialdehyde β (2S,4S)-4- hydrogencarbonate Homoserine dehydrogenase 6.3.5.7): Aspartyl- dehydrogenase activation [acyl-carrier synthetase protein CDS 2.3.1.8): Phosphate protein] N -dihydrolipoyl-L-lysine N -S-acetyldihydrolipoyl-L-lysine (EC 2.3.1.8) dehydratase Acetolactate -lyase: glutamate 5- phosphate sulfite protein] dehydratase, Long-chain- thr Ribonuclease hydratase [isoleucine acetyltransferase complex (EC 2.3.1.12) glyoxylate sn-glycero-3- : Enoyl-CoA Phosphoribosylformimino- dehydrogenase hydroxy-2,3,4,5- dehydrogenase (EC tRNA(Asn) (EC 1.1.1.3) CDS a long-chain protein] (EC 6.1.1.3): a tRNA Ribonuclease Methylmalonyl- acetyltransferase oleate [+ 2 isozymes] L-aspartate 4- (EC 4.2.1.9): synthase: G1RHH-2713 semialdehyde synthase PH (EC (EC 2.3.1.8) : Dihydrolipoamide Phosphate phosphoethanolamine hydratase shikimate 5-aminoimidazole tetrahydrodipicolinate Carbamoyl- (EC 1.1.1.3) CDS FabZ form (EC 4.2.1.59) fatty acid fatty-acid-- reductase 3-hydroxyacyl-CoA CoA epimerase Malate synthase Dihydroxy-acid Acetolactate (EC Acetylornithine amidotransferase Sulfite reductase G1RHH-2666 precursor with 2.7.7.56) CDS D (EC 3.1.26.3) (EC 2.3.1.8) 3-oxopropanoate acetyltransferase (EC a ribonucleic acid [isoleucine semialdehyde L-aspartate 4- [+ 20 isozymes] : 3-hydroxyacyl- Long- CoA ligase an L-threonyl-[tRNA Thr ] dehydrogenase acetyltransferase phosphoribulosylformimino- dehydratase 4-hydroxy- phosphate a 4-phosphooxy- L-homoserine (EC 1.1.1.100) a 5' extension : Ribonuclease (EC 5.1.99.1): G (EC 2.3.3.9): Shikimate kinase synthase 2-aminoprop- aminotransferase [NADPH] hemoprotein acetyl phosphate 2.3.1.8): Phosphate L-aspartate 4- L-homoserine semialdehyde [acyl-carrier-protein] chain-fatty- (EC 6.2.1.3) Thr (EC 1.1.1.35): 3- Homoserine AICAR-phosphate (EC 4.2.1.9) L-homocysteine tetrahydrodipicolinate synthase L-aspartyl- : G1RHH-1018 a tRNA D (EC Methylmalonyl- acetyl phosphate Methylmalonate- Malate synthase [+ 4 isozymes] I (EC 2.7.1.71): large 2-enoate (EC 2.6.1.11): ammonium beta-component acid--CoA : Long- acetyltransferase (S)-3-hydroxy-(11Z) dehydrogenase semialdehyde reductase (EC large chain Asn homoserine O- 3-hydroxyacyl-[acyl-carrier- Ribonuclease hydroxyacyl-CoA CoA epimerase semialdehyde G (EC 2.3.3.9) CDS Shikimate kinase I 3-methyl-2- subunit (EC Acetylornithine Homoserine [tRNA ] (EC 1.8.1.2): Sulfite [+ 3 isozymes] 3.1.26.3) CDS Acetate kinase (EC 2.3.1.8) Homoserine O- acetyltransferase: ligase (EC chain-fatty- dehydrogenase (EC -octadecenoyl-CoA (EC 1.1.1.3): Homoserine 1.17.1.8): 4-hydroxy- aminotransferase (EC 6.3.5.5) dehydrogenase protein] dehydratase, a (3R,11Z)-3- P protein (EC 5.1.99.1) Acetate kinase (EC dehydrogenase (EC 2.7.1.71) CDS Imidazole glycerol oxobutanoate Acetolactate reductase [NADPH] 6.2.1.3) acid--CoA 3-[(3aS,4S,5R,7aS)-5-hydroxy- (EC 2.7.2.1): acetyl-CoA (S)-malate Homoserine dehydrogenase tetrahydrodipicolinate : Carbamoyl- succinyltransferase (EC 1.1.1.3): Aspartyl-tRNA(Asn) G1RHH-1902 FabA form (EC 4.2.1.59) hydroxyoctadec- component (R)-methylmalonyl- 2.7.2.1): Acetate kinase (EC 1.2.1.27): D-gluconate phosphate synthase (EC hemoprotein : Long- ligase (EC 7a-methyl-1-oxo-octahydro-1H- Acetate kinase dehydrogenase (EC 1.1.1.3): reductase phosphate (EC 2.3.1.46): Homoserine amidotransferase : 3-hydroxyacyl- 11-enoyl-[acp] (EC 3.1.26.5): CoA (EC 2.7.2.1) CDS Methylmalonate- degradation a peptidoglycan UDP-N-acetyl- a peptidoglycan L-alanyl-γ-D- β a mitochondrial shikimate 3-phosphate synthase cyclase 2-isopropylmalate small 2-iminopropanoate chain-fatty- Seryl-tRNA (EC 2.7.2.1) CDS an odd numbered straight a 1-acyl-sn-glycero- 3-oxo-(5Z)- pyridoxine -D-fructofuranose (EC 1.1.1.3) CDS Branched-chain N-acetyl-L- synthase G1RHH-1902 O-acetyl-L-homoserine [acyl-carrier-protein] Ribonuclease triacylglycerol inden-4-yl]-3-oxopropanoyl-CoA semialdehyde 16-hydroxypalmitate 3,4-dihydroxyphenylglycol isobutanoate 3-oxo-myristoyl-CoA (6E)-8-hydroxygeranial succinate 2-methylbutanol carbamoyl glutamyl-L-lysyl- leukotrien subunit (EC Homoserine (S)-2,3,4,5- dehydrogenase subunit: Aspartyl- hydrogen sulfide Long-chain- 3-hydroxyacyl- synthetase Acetate kinase (EC chain 2,3,4-saturated fatty acid gly hydroxypyruvate dimer (E. faeciums) 3-phosphocholine L-ornithine α-D-muramoyl- di-trans,octa-cis dimer (S. aureus) dodecenoyl-CoA a lignoceroyl-[acp] 1-phosphate preprotein subunit (EC 4.1.3.-) synthase (EC amino acid met acid--CoA Methylmalonyl- Acetate kinase D-gluconate phosphate 5'-phosphate ornithine large chain (EC 1.1.1.3) CDS tRNA(Asn) [acyl-carrier- P protein degradation dehydrogenase Long-chain-fatty-acid-- Long-chain-fatty-acid-- Alcohol dehydrogenase, Acetyl-coenzyme A 3-ketoacyl-CoA thiolase Alcohol dehydrogenase, D-alanyl-D-alanine Alcohol dehydrogenase, γ D-alanyl-D-alanine D-alanyl-D-alanine 5-Enolpyruvylshikimate- : Imidazole glycerol 2.3.3.13): 2- dehydrogenase tetrahydrodipicolinate O-succinyl-L- fatty-acid-- (EC 6.1.1.11) CoA mutase 2.7.2.1): Acetate kinase Serine--glyoxylate Succinyl-CoA ligase Lysophospholipase Ornithine L-alanyl- -D- -undecaprenyl D-alanyl-D-alanine 3-ketoacyl- Pyridoxal-5'-phosphate 3-oxoacyl-[acyl- Fructose- including a L-homoserine aminotransferase (S)-2-aceto-2- cys ligase (EC 3-ketoacyl-CoA (EC 2.7.2.1): Gluconokinase 3-phosphate synthase (EC 1.1.1.3) CDS homoserine amidotransferase a (2E)-tetradec-2-enoyl-[acp] CoA ligase protein] : Seryl-tRNA component (EC (EC 2.7.2.1) CDS CoA ligase (EC 6.2.1.3) CoA ligase (EC 6.2.1.3) zinc containing (EC 1.1.1.1) synthetase (EC 6.2.1.1) (EC 2.3.1.16) @ Acetyl- zinc containing (EC 1.1.1.1) [ADP-forming]: carboxypeptidase (EC 3.1.1.5); zinc containing (EC 1.1.1.1) carbamoyltransferase glutamyl-L- phosphate carboxypeptidase CoA thiolase bisphosphate mitochondrial phosphate synthase isopropylmalate 2,3,4,5- Acetylornithine Carbamoyl- ser thiolase (EC 2.3.1.16) (EC 5.4.99.2): Acetate kinase (EC 2.7.1.12): aminotransferase (EC Phospho-N- carboxypeptidase phosphatase carrier-protein] (EC 2.5.1.19): 5- (EC 2.6.1.42): hydroxybutanoate L-homoserine Aspartyl-tRNA(Asn) O-acetylhomoserine Long- (EC 6.2.1.3) dehydratase, a triglyceride acetyl-CoA : Long-chain-fatty- : Long-chain-fatty- : Alcohol dehydrogenase, : Acetyl-coenzyme A CoA acetyltransferase (EC : Alcohol dehydrogenase, Succinyl-CoA ligase (EC 3.4.16.4): D- Monoglyceride : Alcohol dehydrogenase, lysyl-D-alanine (EC 3.4.16.4): D- (EC 2.3.1.16) aldolase class targeting sequenceMitochondrial synthase tetrahydropyridine- deacetylase/ phosphate synthetase (EC Methylmalonyl- (EC 2.7.2.1) CDS Gluconokinase 2.6.1.45): Serine--glyoxylate (EC 2.1.3.3): Ornithine acetylmuramoyl- (EC 3.4.16.4): D- (EC 3.1.3.74), synthase, KASI Branched-chain Ketol-acid O-acetylhomoserine amidotransferase sulfhydrylase Enoyl-[acyl-carrier-protein] FabZ form Lipase (EC @ Acetyl-CoA acetate acid--CoA ligase (EC acid--CoA ligase (EC zinc containing (EC synthetase (EC 6.2.1.1) 2.3.1.9): 3-ketoacyl-CoA zinc containing (EC alanyl-D-alanine zinc containing (EC alanyl-D-alanine processing Enolpyruvylshikimate- (EC 2.3.3.13) L-homoserine pyruvate 2,6-dicarboxylate N- Succinyl- chain-fatty- : Long- 6.1.1.11) CDS CoA mutase aminotransferase (EC [ADP-forming] beta lipase (EC carbamoyltransferase alanyl-D-alanine @ Acetyl-CoA Alphaproteobacterial (EC 2.3.1.41): I (EC 4.1.2.13) synthase ser acetyltransferase (EC 2.7.1.12) pentapeptide- 3-phosphate AICAR D-erythro-imidazole- amino acid reductoisomerase sulfhydrylase (EC 2.5.1.49) / O- reductase [NADH] (EC chain-fatty- (EC 4.2.1.59): an L-seryl-[tRNA ] 3.1.1.3): Lipase thiolase (EC 2.3.1.16) @ Succinyl-CoA ligase carboxypeptidase 3.1.1.23); putative: carboxypeptidase acetyltransferase : Fructose- peptidase-like succinyltransferase diaminopimelate acid--CoA (EC 5.4.99.2) acetate Long-chain-fatty-acid-- Long-chain-fatty-acid-- Alcohol dehydrogenase Acetyl-coenzyme A Serine--glyoxylate alcohol dehydrogenase, Alcohol dehydrogenase (EC transferase carboxypeptidase type: Pyridoxal- 3-oxoacyl-[acyl- glycerol-phosphate aminotransferase (EC 1.1.1.86) L-isoleucine small chain (EC 2.5.1.49) / O- Aspartyl-tRNA(Asn) succinylhomoserine 1.3.1.9): Enoyl-[acyl- (EC 3.1.1.3) CDS (EC 2.3.1.9): 3- CDS Degradation/Utilization/Assimilation - Other (EC (EC protein (EC ligase (EC acid--CoA 3-hydroxyacyl- a tRNA ser D-gluconate CoA ligase (EC 6.2.1.3) CoA ligase (EC 6.2.1.3) (EC 1.1.1.1): Alcohol synthetase (EC 6.2.1.1) [+ 3 isozymes] zinc-containing: alcohol [ADP-forming] alpha Lysophospholipase (EC 1.1.1.1): Alcohol (EC 2.3.1.9): 3- 5'-phosphate bisphosphate O-phospho- (2S)-2- biosynthesis II (EC 2.3.1.117): 2,3,4,5- desuccinylase (EC 6.3.5.5) amidotransferase sulfhydrylase (EC a 1,2-diglyceride ketoacyl-CoA aminotransferase (EC L-citrulline (EC 2.7.8.13) (EC carrier-protein] 5-enolpyruvoyl-shikimate 3-phosphate Imidazoleglycerol- [+ 2 isozymes] : Ketol-acid Homoserine O- succinylhomoserine carrier-protein] reductase 6.2.1.3) ligase (EC [acyl-carrier- succinyl-CoA [+ 2 isozymes] (EC 3.1.1.5); [+ 2 isozymes] ketoacyl-CoA aldolase 3.4.24.64): isopropylmalate tetrahydropyridine- and related : Carbamoyl- 6-phosphate : Long-chain-fatty- : Long-chain-fatty- dehydrogenase : Acetyl-coenzyme A 2.6.1.45): Serine--glyoxylate acetyl-CoA lauroyl-CoA dehydrogenase, dehydrogenase : Phospho-N- γ phosphatase (EC synthase, L-homoserine O-phospho- subunit B (EC 2.5.1.48): G1RHH-2713 thiolase (EC a peptidoglycan tetramer a peptidoglycan L-alanyl-[+ 2 isozymes]-D- Mitochondrial phosphate reductoisomerase succinyltransferase sulfhydrylase [+ 2 isozymes] : Long- protein] octane oxidation phosphate ADP succinyl-CoA thiolase (EC class I (EC pyruvate 2,6-dicarboxyla deacylases: phosphate 6.3.5.6) @ acid--CoA ligase (EC acid--CoA ligase (EC (EC 1.1.1.1) CDS synthetase (EC 6.2.1.1) aminotransferase (EC zinc-containing Lysophospholipase (EC 1.1.1.1) CDS acetylmuramoyl- pyridoxine leukotriene-E4 Chorismate synthase 3-isopropylmalate (EC 1.1.1.86) (EC 2.3.1.46): (EC 2.5.1.48): L-homoserine [+ 5 isozymes] stearoyl-CoA 2.3.1.16) @ nylon-6 oligomer degradation D-ala with a D,D cross-link undecaprenyl- D-ala with D,D cross- D-ala glutamyl-L- a 3-oxohexacosanoyl-[acp] processing Threonine dehydratase chain-fatty- 2.3.1.16) @ an MPP- val (R)- N-succinyl- Acetylornithine synthase Glutamyl-tRNA(Gln) a myristoyl-[acp] 3-hydroxyacyl- an odd numbered straight chain 3,4-dihydroxyphenylglycolaldehyde ser glyoxylate (6E)-8-oxogeranial (Enterococcus faecium) L2 (EC 3.1.1.5): 2-methylbutanal diphospho-pentapeptide-N- link (S. aureus) lysyl-D-alanine D-glyceraldehyde DHAP peptidase-like synthase (EC 4.2.3.5): (EC 4.2.1.19): dehydratase: 3- (R)-2,3-dihydroxy- G1RHH-1902 cys G1RHH-2713 Threonine acid--CoA [+ 3 isozymes] diphosphate AMP AMP diphosphate 16-hydroxypalmitoyl-CoA isobutanoyl-CoA AMP diphosphate 2-amino-6- small chain amidotransferase [acyl-carrier- Prolyl-tRNA NADH 2,3,4-saturated fatty acyl CoA Lysophospholipase [+ 3 isozymes] processed Chorismate synthase isopropylmalate citramalate [+ 2 isozymes] 6-aminohexanoate acetylmuramoyl- a peptide (EC 4.2.3.1) Imidazoleglycerol- 3-methylpentanoate ketopimelate O-acetylhomoserine synthase ligase (EC synthetase a 2-acylglycerol nylon-6 polymer L2 (EC 3.1.1.5) CDS UMP (3Z)-dec-3- mitochondrial (EC 4.2.3.5) CDS dehydratase synthase subunit B (EC L-homocysteine 3-oxoacyl-[acyl-carrier- a long-chain protein] 3-[(3aS,4S,5R,7aS)-5-hydroxy- Amine and Polyamine Degradation cyclic dimer L-alanyl-γ-D- acetyl-CoA : Threonine phosphate O-succinyl-L- N-succinyl-L,L- carbamoyl sulfhydrylase (EC 4.2.3.1) sn-glycero-3- enoyl-CoA protein small 3- Dihydroxy-acid (EC L-ornithine 6.3.5.7): Aspartyl- protein] synthase, acyl-CoA dehydratase, (EC 6.1.1.15), acetyl-CoA 7a-methyl-1-oxo-octahydro- a carboxylate glutamyl-L- synthase chorismate dehydratase dehydratase homoserine diaminopimelate phosphate (EC 2.5.1.49) / O- : Threonine bacterial type: phosphocholine isopropylmalate 2.3.1.182) tRNA(Asn) KASI (EC 2.3.1.41): 3- FabA form 1H-indene-4-carboxyl-CoA octane a reduced rubredoxin lysyl- D-alanine (EC 4.2.3.1) aminotransferase succinylhomoserine synthase L-glutamate allantoin degradation dehydratase large (EC 4.2.1.9): : (R)- amidotransferase oxoacyl-[acyl-carrier- (EC 4.2.1.59): Prolyl-tRNA glycine betaine degradation I glycine betaine creatinine degradation II choline-O-sulfate degradation CDS imidazole acetol-phosphate (EC 4.2.3.1) pro IV (anaerobic) 4-aminobutanoate Dihydroxy-acid alternative Ornithine sulfhydrylase biosynthesis III 3-hydroxyacyl- synthetase 6-aminohexanoate a nylon-6 O-acetylhomoserine citramalate protein] synthase, an uncharged a 1-monoglyceride degradation II (mammalian) degradation III Alkane-1 monooxygenase Anthranilate synthase, Chorismate mutase dehydratase (EC 2.6.1.17): carbamoyltransferase (EC 2.5.1.48): O- CDS (EC 6.1.1.15), linear dimer linear oligomer 2,3,5,6- RNase III mRNA Nα,Nε-diacetyl-lysyl- UDP 2-trans, 4- 2-isopropylmaleate sulfhydrylase synthase [acyl-carrier- tRNA 18-hydroxystearate 6-trans-3-oxo-tridecenoyl-CoA pristanate 5-hydroxytryptophol a 3-oxoacyl-CoA glutathione a β-D-mannoside 8 3-methylbutanol glutathione monochlorobimane pyridoxamine N-acetyl- thr ami: Anthranilate I (EC 5.4.99.5): Histidinol-phosphate an L-asparaginyl- 2-oxoglutarate 3-oxoacyl-[acyl-carrier- Pro (5R,7aS)-5-hydroxy-7a-methyl- (S)-(+)-allantoin glycine betaine creatinine choline sulfate (EC 1.14.15.3): Alkane- 6-aminohexanoate- 6 37 N -acetylspermidine processing H O diphosphate L-canavanine (EC 4.2.1.9) N-succinyl-L,L- (EC 2.1.3.3): Ornithine acetylhomoserine an L-prolyl-[tRNA ] N -dimethylallyladenosine in tRNA a sulfurated [sulfur carrier] tetrachlorohydroquinone 2 D-alanyl-D-alanine a myristoyl-[acp] an arachidoyl-[acp] undecadienoyl-C (EC 2.5.1.49) / O- (EC Asn protein] glycine betaine 5'-phosphate L-citrulline synthase, aminase Chorismate mutase aminotransferase thr [tRNA ] protein] synthase, Lysophospholipase 1-oxo-3,5,6,7-tetrahydro- Betaine--homocysteine 4-aminobutanoate Choline-sulfatase (EC 1 monooxygenase dimer hydrolase Beta- substrate Ribonucleotide reductase 3-isopropylmalate diaminopimelate carbamoyltransferase sulfhydrylase (EC Glutamate synthase Pro 6-aminohexanoate- Long-chain-fatty-acid-- 3-ketoacyl-CoA thiolase Long-chain-fatty-acid-- Alcohol dehydrogenase, 3-ketoacyl-CoA thiolase Glutathione Acetylspermidine Alcohol dehydrogenase, Glutathione D-alanyl-D-alanine Arginase/agmatinase/ (S)-3-methyl-2- succinylhomoserine 2.3.1.182) a tRNA Betaine--homocysteine Succinate dehydrogenase Ribonuclease Manganese- of class II (coenzyme Pyridoxal-5'-phosphate 3-oxoacyl-[acyl- 3-oxoacyl-[acyl- Acetylornithine L-serine component I (EC 5.4.99.5) CDS (EC 2.6.1.9) @ (EC [NADPH] large KASII (EC 2.3.1.179): cyclopropane a (2E,11Z)-octadeca- (EC 3.1.1.5); 2H-indene-4-carboxyl-CoA S-methyltransferase Gamma- 3.1.6.6): Choline-sulfatase (EC 1.14.15.3) CDS (EC 3.5.1.46): 6- dimer hydrolase CoA ligase (EC 6.2.1.3) (EC 2.3.1.16) @ Acetyl- CoA ligase (EC 6.2.1.3) zinc containing (EC 1.1.1.1) (EC 2.3.1.16) @ Acetyl- mannosidase deacetylase (EC 3.5.1.48) zinc containing (EC 1.1.1.1) S-transferase formimionoglutamate dehydratase: 3- oxopentanoate N-succinyl- S-methyltransferase hydrophobic membrane S-transferase D (EC 3.1.26.3) dependent inorganic carboxypeptidase phosphatase carrier-protein] carrier-protein] deacetylase/ Anthranilate synthase, Aromatic-amino-acid sulfhydrylase (R)-citramalate 3-oxoacyl-[acyl-carrier- Monoglyceride (EC 2.1.1.5): Betaine- aminobutyrate:alpha- (EC 3.1.6.6) CDS (EC 3.2.1.25) B12-dependent) (EC dehydratase, isopropylmalate L,L-2,6- L-cystathionine chain (EC 1.4.1.13) fatty acid (CFA) 2,11-dienoyl-[acp] (EC 2.1.1.5): Betaine- N-methylhydantoin Alkane-1 monooxygenase aminohexanoate- (EC 3.5.1.46): 6- anchor protein: Succinate : Long-chain-fatty- CoA acetyltransferase (EC : Long-chain-fatty- : Alcohol dehydrogenase, CoA acetyltransferase (EC domain protein: ; Deacetylases, including : Ribonuclease : Alcohol dehydrogenase, pyrophosphatase (EC domain protein: (EC 3.4.16.4): D- hydrolase: Arginase/ (EC 3.1.3.74), Branched-chain (EC 2.5.1.48): lipase (EC -homocysteine S- choline 6-caprolactam 1.17.4.1): Ribonucleotide synthase, KASI synthase, KASI Succinyl- beta subunit amidotransferase aminotransferase dehydratase diaminopimelate : Glutamate protein] synthase, biosynthesis protein S-nitrosylation ketoglutarate (EC 1.14.15.3): Alkane- dimer aminohexanoate- acid--CoA ligase (EC 2.3.1.9): 3-ketoacyl-CoA acid--CoA ligase (EC zinc containing (EC 2.3.1.9): 3-ketoacyl-CoA Glutathione : Beta- yeast histone deacetylase zinc containing (EC Glutathione alanyl-D-alanine agmatinase/ prephenate G1RHH-2713 Enoyl-[acyl- -homocysteine S- dehydrogenase hydrophobic D (EC 3.6.1.1): Manganese- reductase of class II Alphaproteobacterial (EC 2.3.1.41): (EC 2.3.1.41): diaminopimelate (EC 4.3.1.17) (EC 2.6.1.57): amino acid L-citrulline synthase [NADPH] a [phospholipid] and denitrosylation 3.1.1.23); putative: allantoate methyltransferase N-methylhydantoinase aminotransferase 1 monooxygenase hydrolase (EC dimer thiolase (EC 2.3.1.16) @ thiolase (EC 2.3.1.16) @ mannosidase and acetoin utilization S-transferase formimionoglutamate small 3- N-succinyl-L,L- carrier- (5R,7aS)-7a-methyl-1,5- methyltransferase Choline dehydrogenase Long-chain-fatty-acid-- Long-chain-fatty-acid-- Alcohol dehydrogenase S-transferase 3.1.26.3) CDS Alcohol dehydrogenase dependent inorganic carboxypeptidase type: Pyridoxal- 3-oxoacyl-[acyl- 3-oxoacyl-[acyl- desuccinylase Histidinol-phosphate aminotransferase a 3-oxohexadecanoyl-[acp] olefinic fatty acid Phenylalanyl- Lysophospholipase A (EC 3.5.2.14): N- (EC 2.6.1.19): Gamma- tRNA-i(6)A37 (EC 3.2.1.25) Ribonucleotide reductase / L-serine isopropylmalate O-acetylhomoserine diaminopimelate L-cystathione large chain (EC dioxo-3,5,6,7-tetrahydro- N,N-dimethylglycine (EC 1.14.15.3) CDS hydrolase (EC CoA ligase (EC 6.2.1.3) [+ 3 isozymes] domain protein protein: Acetylspermidine (EC 1.1.1.1): Alcohol + domain protein (EC anthranilate Cyclopropane- protein] a [protein]- N,N-dimethylglycine (EC 1.1.99.1): G1RHH-1942 methylthiotransferase: CoA ligase (EC 6.2.1.3) [+ 3 isozymes] (EC 1.1.1.1): Alcohol Ribonuclease phosphate H Arginase (EC 3.5.3.1) 5'-phosphate carrier-protein] carrier-protein] and related dehydratase, Prephenate Cyclohexadienyl aminotransferase (EC (EC 2.6.1.42): β-lyase: tRNA synthetase: (EC 3.1.1.5); methylhydantoinase aminobutyrate:alpha- CDS deacetylase (EC of class II (coenzyme dehydratase large sulfhydrylase citraconate desuccinylase Argininosuccinate [+ 9 isozymes] fatty-acyl- reductase L-cysteine 2H-indene-4-carboxyl-CoA : Long-chain-fatty- acetyl-CoA 4-trans-undecenoyl-CoA : Long-chain-fatty- dehydrogenase acetyl-CoA an acyl-CoA [+ 7 isozymes] dehydrogenase [+ 7 isozymes] [+ 2 isozymes] : G1RHH-1884 phosphatase (EC synthase, synthase, deacylases: dehydratase (EC dehydrogenase (EC Branched-chain 3-oxoacyl-[acyl-carrier Phenylalanyl- A (EC 3.5.2.14) CDS ketoglutarate Choline dehydrogenase 1-octanol tRNA-i(6)A37 β-D- III (EC 3.1.26.3) alpha subunit Anthranilate (EC 2.5.1.49) / O- (EC 3.5.1.18): synthase G1RHH-2713 Dimethylglycine acid--CoA ligase (EC acid--CoA ligase (EC (EC 1.1.1.1) CDS 2,3,5-trichloro-6-(glutathion- a non glycosylated (EC 1.1.1.1) CDS Nα,Nε-diacetyl- B12-dependent) (EC L-histidinol phosphate (2R,3S)-3- amino acid glu protein] reductase (EC phospholipid [NADH] (EC tRNA synthetase glycerol Dimethylglycine (EC 1.1.99.1): Choline methylthiotransferase CDS acetate spermidine : Ribonuclease (glutathion-S-yl)-bimane D-ala urea L-canaline pyridoxamine a 3-oxohexadecanoyl-[acp] a 3-oxodocosanoyl-[acp] Acetylornithine (3E)-undec-3-enoyl- (EC 4.3.1.17): 4.2.1.51): Prephenate 1.3.1.12)(EC 1.3.1.43) L-arginine biosynthesis II (acetyl cycle) dehydrogenase (EC 6-aminohexanoate 6 S-yl)-hydroquinone sugar acceptor mannopyranose 1.17.4.1): Ribonucleotide phosphoribosyltransferase isopropylmalate succinylhomoserine N-succinyl-L,L- (EC 6.3.4.5): synthase 1.3.1.9): Enoyl- (S)-ureidoglycine N-methylhydantoinase Gamma- 2-methylsulfanyl-N - 5-hydroxyindole acetaldehyde 3-methylbutanal lysyl-D-alanine dehydratase (EC : Cyclohexadienyl aminotransferase 1.1.1.100): G1RHH-1018 beta chain dehydrogenase (EC dehydrogenase octanol dehydrogenase: met 5'-deoxyadenosine an unsulfurated [sulfur carrier] III (EC reductase of class II [+ 2 isozymes] G1RHH-2694 (EC 2.4.2.18): Anthranilate sulfhydrylase diaminopimelate Argininosuccinate 2-aminoprop- (EC 2.1.1.79) (3R)-2-(2-carboxyethyl)- 1.5.99.2): Dimethylglycine B (EC 3.5.2.14): N- aminobutyrate:alpha- dimethylallyladenosine 37 in tRNA AMP diphosphate 18-hydroxystearoyl-CoA AMP diphosphate pristanoyl-CoA Histidinol- 3-isopropylmalate [acyl-carrier- Phenylalanyl- a [protein] 3- 1.5.99.2): Dimethylglycine (EC 1.1.99.1) CDS G1RHH-1942 3.1.26.3) CDS acetate L-citrulline phosphoribosyltransferase (EC 4.2.1.51) CDS dehydrogenase (EC [+ 2 isozymes] (EC 2.5.1.48): O- synthase L-homocysteine 2-enoate [+ 3 isozymes] Ureidoglycine dehydrogenase (EC methylhydantoinase ketoglutarate RNase III dUDP [+ 3 isozymes] (2R,3S)-3- L,L- N-acetylglutamyl-phosphate , plant type: protein] phe 3-methyl-6-oxocyclohex- dehydrogenase (EC phosphatase dehydrogenase acetylhomoserine tRNA synthetase nitrosothio- aminohydrolase: an mRNA fragment processing (EC 6.3.4.5) 1-ene-1-carboxyl-CoA Dimethylglycine B (EC 3.5.2.14) CDS aminotransferase betaine aldehyde (2Z)-2-aminobut- Anthranilate [alternative form] (EC 1.1.1.85): 3- methylmalate diaminopimelate N-acetyl-gamma- a (3R)-3-hydroxyhexadecanoyl-[acp] a [phospholipid]G1RHH-2591 reductase alpha chain L-alanine Dimethylglycine 1-octanal ile sulfhydrylase (EC G1RHH-2287 dehydrogenase (EC (EC 2.6.1.19): Gamma- product mRNA 2-enoate phosphoribosyltransferase 3-phenyl-2-oxopropanoate 3-(4-hydroxyphenyl)pyruvate (EC 3.1.3.15) isopropylmalate L-arginino- glutamyl-phosphate cyclopropane [+ 2 isozymes] an L-phenylalanyl-[tRNA Phe ] dehydrogenase (EC 6-oxohexanoate like (EC 2.4.2.18) Diaminopimelate succinate reductase (EC 1.2.1.38) 1.5.99.2): G1RHH-2552 N-carbamoylsarcosine aminobutyrate:alpha- Betaine aldehyde Aldehyde dehydrogenase : Histidinol- dehydrogenase Glutamate N- Acetylglutamate 3-hydroxyacyl-[acyl-carrier- fatty acid a tRNA Phe (S)-ureidoglycolate 1.5.99.2): G1RHH-2552 Aspartate epimerase ketoglutarate dehydrogenase (EC (EC 1.2.1.3): Aldehyde a DNA containing : Anthranilate Biosynthetic Argininosuccinate 2-iminopropanoate : N-acetyl-gamma- protein] dehydratase, 3-oxo-2-(cis-2'-pentenyl)- (R)-1- 2-bromo-3-(4- 4-hydroxy-2- 3-hydroxy-5- a [protein] N-terminal- a [lysine-biosynthesis- 4-hydroxy- 2-trans, 4-tr phosphatase (EC L-cystathionine (EC 5.1.1.7): acetyltransferasekinase (EC 2.7.2.8): a cis-vaccenoyl-[acp] 9-carboxy-6-methyl-3,7- sarcosine succinate 1.2.1.8): Betaine aldehyde a peptidoglycan (2E)-hexadecenoate γ-butyrobetaine 2-oxoglutarate (2R,3S)-β-methylmalyl-CoA adenosylcobyrate glutathione 5'-deoxyadenosine (R)-3-hydroxybutanoate methyl red acetate dCDP glutathione phosphoribosyltransferase aminotransferase (EC Aromatic amino acid met glutamyl-phosphate dehydrogenase cyclopentane-1-(3-oxobutanoyl)-CoA nitrophenyl)propanoate trp an apurinic/ formyl-L-methionine roseoflavin a behenoyl-[acp] protein LysW]- 2-nonenal [alternative form] 2-oxobutanoate lyase (EC 4.3.2.1): (EC 2.3.1.35) / AcetylglutamateN- kinase FabZ form (EC 4.2.1.59) a [protein]- sarcosine semialdehyde aminopropan-2-ol oxoglutarate oxohexanoyl-CoA Ribonucleotide reductase ATP undecadienoyl-C 2.6.1.1): Aspartate aminotransferase (2S)-2-isopropyl- Diaminopimelate S-nitrosoglutathione dioxononanoyl-CoA dehydrogenase (EC (EC 1.2.1.3) CDS N-acetylmuramoyl-L- Long-chain-fatty-acid-- 3-ketoacyl-CoA thiolase Gamma-butyrobetaine,2- L-malyl-CoA/beta- Glutathione S- 5'-methylthioadenosine D-beta-hydroxybutyrate apyrimidinic site 5'-phosphate C-terminal-γ-(L- 2-iminobutanoate Argininosuccinate (EC 2.7.2.8) CDS : 3-hydroxyacyl- Adenosylcobinamide- 4-hydroxy-2-oxoglutarate Aromatic-amino-acid Endonuclease FMN-dependent Acetyl- Peptide 3-oxoacyl-[acyl- Glutathione aminotransferase 3-oxosuccinate L-cysteine biosynthesis epimerase acetylglutamate L-cysteine Sarcosine oxidase: creatinine degradation I succinate- alanine amidase (EC oxoglutarate dioxygenase: dehydrogenase (EC of class II (coenzyme Acetylglutamate N-(5-phosphoribosyl)-anthranilate beta (EC 2.6.1.57) histidinol lyase (EC [acyl-carrier-protein] Sarcosine dehydrogenase glycine betaine [+ 5 isozymes] adipate CoA ligase (EC 6.2.1.3) (EC 2.3.1.16) @ Acetyl- methylmalyl-CoA lyase (EC phosphate synthase transferase domain phosphorylase aldolase (EC 4.1.3.16) NADH- CoA:acetoacetyl- deformylase Riboflavin kinase glutamyl)-L-glutamate S-transferase VI (from L-methionine) L-cystathione Acetolactate (EC 5.1.1.7) synthase (EC N-carbamoyl- Sarcosine oxidase beta aminotransferase (EC III (EC 4.2.99.18) B12-dependent) (EC carrier-protein] (EC 2.6.1.1) : Biosynthetic Methionyl-tRNA S-(hydroxymethyl) 3-ketoacyl-CoA (EC 1.5.99.1): Sarcosine sarcosine semialdehyde 3.5.1.28): N-acetylmuramoyl- : Long-chain-fatty- CoA acetyltransferase (EC G1RHH-1939 4.1.3.-): L-malyl-CoA/beta- (EC 6.3.1.10): protein: Glutathione (EC 2.4.2.28): 5'- @ 2-dehydro-3- 1.1.1.30): G1RHH-1799 azoreductase: CoA transferase, (EC 3.5.1.88) (EC 2.7.1.26) / FMN kinase (EC domain Phosphoribosylanthranilate β-lyase: synthase 4.3.2.1) CDS 2.3.1.1): Glutamate N- 3-hydroxyacyl-[acyl-carrier- 2-oxoglycine 2.6.1.57): Aromatic-amino- : Endonuclease 1.17.4.1): Ribonucleotide synthase, KASI Aromatic amino acid putative histidinol pyruvate synthetase glutathione thiolase (EC 2.3.1.16) subunit (EC Sarcosine dehydrogenase: octanoate L-alanine amidase (EC acid--CoA ligase (EC 2.3.1.9): 3-ketoacyl-CoA methylmalyl-CoA lyase (EC S-transferase methylthioadenosine 2.7.2.8): [+ 8 isozymes] large subunit meso- cis-vaccenate dehydrogenase creatinine Gamma-butyrobetaine Adenosylcobinamide- deoxyphosphogluconate acid aminotransferase (EC D-beta-hydroxybutyrate III (EC FMN-dependent alpha subunit (EC : Peptide adenylyltransferase (EC 2.3.1.41): protein: isomerase (EC 5.3.1.24): G1RHH-2713 acetyltransferase (EC protein] dehydratase, (EC 6.1.1.10): @ Acetyl-CoA oxidase delta subunit (EC Aldehyde reductase of class II Acetylglutamate [+ 2 isozymes] dehydrogenase met diaminopimelate arg dehydrogenase (EC 1.5.99.1) CDS Sarcosine Sarcosine oxidase: Creatinine N-acetylmuramoyl-L- Long-chain-fatty-acid-- thiolase (EC 2.3.1.16) @ dioxygenase (EC 1.14.11.1) Malyl-CoA lyase (EC phosphate domain protein phosphorylase (EC aldolase (EC dehydrogenase (EC NADH- 2.8.3.8): Acetyl- deformylase (EC (EC 2.7.7.2): Glutathione Phosphoribosylanthranilate 4-methyl-2- (EC 2.2.1.6): glu N-acetyl-L-glutamate N-acetyl-L-glutamate 5-semialdehyde FabA form (EC 4.2.1.59) Sarcosine oxidase alpha Long-chain-fatty-acid-- 4.2.99.18) CDS 3-oxoacyl-[acyl- 2-oxobutanoate phe (but probably not): S-adenosylmethionine Methionyl-tRNA (EC 1.1.1.284): S- acetyltransferase dehydrogenase (EC dehydrogenase alanine amidase (EC synthase (EC 4.1.2.14): 4-hydroxy-2- Biosynthetic a 3'-terminal a 5'-phospho- azoreductase CoA:acetoacetyl- 3.5.1.88) CDS Ribonucleotide reductase Riboflavin kinase kinase (EC S-transferase oxopentanoate Acetolactate met Sarcosine dehydrogenase Sarcosine oxidase amidohydrolase (EC CoA ligase (EC 6.2.1.3) CoA ligase (EC 6.2.1.3) [+ 3 isozymes] : Gamma-butyrobetaine 4.1.3.24): Malyl-CoA [+ 7 isozymes] 5-deoxy-α-ribose 1.1.1.30): D-beta- carrier-protein] a [lysine-biosynthesis- isomerase (EC putative histidinol synthetase 2-aminoprop- Diaminopimelate Acetylornithine : 3-hydroxyacyl- synthetase (hydroxymethyl) (EC 2.3.1.9): 3- subunit (EC Sarcosine B (EC 1.2.1.22) 2-(glutathion-S-yl)-3-(4- adenine Aromatic amino acid of class II (coenzyme 2.7.2.8) CDS tyr L-homocysteine synthase 1.5.99.1): Sarcosine beta subunit (EC 3.5.2.10): Creatinine 3.5.1.28): N-acetylmuramoyl- : Long-chain-fatty- acetyl-CoA (+)-7-epi-jasmonoyl-CoA dioxygenase (EC lyase (EC 4.1.3.24) CDS adenosylcobinamide bromide oxoglutarate aldolase (EC hydroxybutyrate unsaturated sugar [DNA] CDS CoA transferase, [+ 2 isozymes] (EC 2.7.1.26) / FMN synthase, domain 1-(o-carboxyphenylamino)-1'- Branched-chain 2-enoate decarboxylase [acyl-carrier-protein] (EC 6.1.1.10) oxidase gamma subunit (EC (EC 1.5.99.1): Sarcosine : Long-chain-fatty- 1-phosphate aminotransferase beta 3-hydroxy-5- roseoflavin adenine protein LysW]-C- Acetolactate dehydrogenase (but (EC 2.5.1.6): S- superpathway of L-cysteine aminotransferase an L-methionyl- glutathione ketoacyl-CoA carbamoyl oxamate dehydrogenase Sarcosine oxidase amidohydrolase L-alanine amidase (EC acid--CoA ligase (EC nitrophenyl)propanoate dehydrogenase (EC N,N-dimethyl-1,4- an N-terminal L- B12-dependent) (EC protein deoxyribulose 5'-phosphate amino acid large (EC 4.1.1.20): dehydrogenase succinate acid--CoA ligase (EC succinate L-carnitine propanoyl-CoA glyoxylate pyruvate glyoxylate anthranilate acetyl-CoA formate dinucleotide a 3-oxotetracosanoyl-[acp] terminal-γ-(5-phospho- (3E)-undec-3-enoyl- synthase adenosylmethionine biosynthesis (mammalian) (EC 2.6.1.11): [elongator tRNA Met ] dehydrogenase thiolase (EC phosphate [+ 2 isozymes] (EC 1.5.99.1) CDS ditrans,octacis-undecaprenyldiphospho- (EC 2.6.1.57): Biosynthetic phenylenediamine oxohexanoate methionyl-[protein] 1.17.4.1): Ribonucleotide Histidinol subunit (EC (EC 1.5.99.1) CDS delta subunit (EC (EC 3.5.2.10) acetoacetate [+ 7 isozymes] aminotransferase Diaminopimelate Glutamate N- a (2E)-hexadec-2-enoyl-[acp] Met Long-chain-fatty-acid-- a peptidoglycan pentapeptide Aromatic amino acid L-glutamyl)-L-glutamate (glutathion-S- large subunit Indole-3-glycerol synthetase (EC Acetylornithine elongator tRNA 2.3.1.16) @ Sarcosine oxidase N-acetyl-(N-acetylglucosaminyl)muramate AMP diphosphate (2E)-hexadecenoyl-CoA reductase of class II dehydrogenase decarboxylase (EC S-(hydroxysulfenamide) Carbamoyl- Sarcosine phosphate synthase (EC 2.6.1.42): SAM Acetolactate acetyltransferase aminotransferase (EC gly creatine CoA ligase (EC 6.2.1.3) (indol-3-yl)pyruvate yl)-4-hydroxy- (EC 2.2.1.6): (EC 1.1.1.23): met glutathione [+ 3 isozymes] gly dehydrogenase (EC alpha subunit (EC proline betaine CDP Branched-chain 2-iminopropanoate (EC 2.3.1.35) / N- Enoyl-[acyl-carrier-protein] phosphate : Long-chain-fatty- 2-nonenal Acetolactate (EC 4.1.1.48): Indole- L-proline G1RHH-2646 synthase: gln Sarcosine oxidase degradation L-alanine uracil degradation amino acid lys reductase [NADH] (EC synthase Serine 1.5.99.1): Sarcosine Creatinase (EC acid--CoA ligase (EC synthase 3-glycerol phosphate biosynthesis I met Acetolactate S-adenosylmethionine acetylglutamate I (reductive) 1.3.1.9): Enoyl-[acyl- 7-carboxy-4-methyl- large chain Serine dehydrogenase gamma subunit (EC 3.5.3.3): Creatinase synthase (EC biosynthesis I histidinal aminotransferase synthase synthase (EC acetyl-CoA hydroxymethyltransferase large synthetase (EC 2.5.1.6) Carbamoyl-phosphate Lysyl-tRNA 5-oxoheptanoyl-CoA hydroxymethyltransferase (EC 1.5.99.1) CDS [+ 2 isozymes] (EC 3.5.3.3) CDS octanoyl-CoA uracil 2.3.1.1): Glutamate N- carrier-protein] reductase (EC 6.3.5.5) (EC 2.1.2.1): Serine D-proline betaine subunit (EC 3-methyl-2- [+ 2 isozymes] large : S-adenosylmethionine synthase large Secondary Metabolite Biosynthesis synthetase (EC 2.1.2.1): Serine an (S-diacyl-sn-glyceryl)-L- (6Z,9Z,12Z,15Z,18Z,21Z)-3- (6Z,9Z,12Z,15Z,18Z)-3- XXLG xyloglucan (4S)-4-hydroxy- 7,8- dehydro(indole- an N-terminal a peptidyl- a guanine 37 (1S,2R)-1-C-(indol-3- glu putative histidinol [+ 2 isozymes] hydroxylamine : Carbamoyl- hydroxymethyltransferase (EC an L-1-phosphatidylethanolamine 18-hydroxyoleate 3-oxo-(11Z)-octadecenoyl-CoA a proteinogenic (S)-2-chloropropanoate xylitol NaMN glutathione an L-arginyl- a cis,cis-delta19,3 Dihydropyrimidine subunit (EC synthetase (EC acetyltransferasechain (EC 6.3.5.5): (EC N-acetyl-L-ornithine (class I) (EC oxotetracosahexaenoyl-CoA oxotetracosapentaenoyl-CoA leukotriene-C4 oligosaccharide a dodecanoyl-[acp] an arachidoyl-[acp] 3-yl)acetonitrile 3-sulfino-L- dipeptidase a dodecanoyl-[acp] histidinol oxobutanoate SAH hydroxymethyltransferase (EC gly sarcosine cysteinyl-[apolipoprotein] 2-oxoglutarate dihydromonapterin [tRNA Arg ] in tRNA hydroxy-C56:2-[acp Acetolactate yl)glycerol 3-phosphate Glutamate 5- Branched-chain dehydrogenase pyruvate phosphate amino acid Haloacid dehalogenase, Beta- Alcohol dehydrogenase, 5'-nucleotidase (EC Histidinol dehydrogenase leu Acetolactate Carbamoyl-phosphate 6.1.1.6): Lysyl- Apolipoprotein N- Long-chain-fatty-acid-- 3-ketoacyl-CoA thiolase 3-ketoacyl-CoA thiolase 3-ketoacyl-CoA thiolase Gamma- 4-hydroxy-2-oxoglutarate Dihydroneopterin Enoyl-[acyl-carrier- Enoyl-[acyl-carrier- Glutathione alanyl-[protein] Dcp substrateDipeptidyl 3-oxoacyl-[acyl- tRNA synthase: kinase (EC amino acid (but probably not): a palmitoyl-[acp] methylerythritol phosphate pathway II a tRNA Lys synthase ser Arginine- Tryptophan synthase [NADP+] (EC 1.3.1.2) synthase L-arginine degradation L-alanine SAM synthase large chain myo-inositol tRNA synthetase (2E)-7-carboxy-4-methyl- ser L-proline betaine acyltransferase (EC CoA ligase (EC 6.2.1.3) (EC 2.3.1.16) @ Acetyl- (EC 2.3.1.16) @ Acetyl- (EC 2.3.1.16) @ Acetyl- type II (EC 3.8.1.2): galactosidase aldolase (EC 4.1.3.16) aldolase (EC zinc containing (EC 1.1.1.1) 3.1.3.5): G1RHH-2543 protein] reductase protein] reductase S-transferase (Guanine37-N1) - dehydrogenase (EC 2.7.2.11) / superpathway of L-serine large chain Sarcosine Sarcosine oxidase: glutamyltranspeptidase tRNA-protein carboxypeptidase carrier-protein] Acetolactate aminotransferase : Dihydropyrimidine putative histidinol I (arginase pathway) biosynthesis III biosynthesis 5-oxohept-2-enoyl-CoA 2.3.1.-) / Copper : Long-chain-fatty- CoA acetyltransferase (EC CoA acetyltransferase CoA acetyltransferase (EC Haloacid dehalogenase, (EC 3.2.1.23) @ 2-dehydro-3- : Alcohol dehydrogenase, 5-nucleotidase SurE (EC domain protein: methyltransferase 1.1.1.23): G1RHH-2646 beta chain (EC 4.2.1.20) and glycine biosynthesis I small Carbamoyl-phosphate D-glyceraldehyde (class I) (EC dehydrogenase (EC Sarcosine oxidase (EC 2.3.2.2): Gamma- 4.1.2.25) / delta [NADH] (EC 1.3.1.9) [NADH] (EC 1.3.1.9) transferase Dcp (EC 3.4.15.5) synthase, KASI synthase RNA-binding (EC 2.6.1.42): dehydrogenase (but pyruvate Lys L-serine dehydratase, : Tryptophan synthase dehydrogenase subunit (EC an L-lysyl-[tRNA ] ammonium urea degradation II homeostasis acid--CoA ligase (EC 2.3.1.9): 3-ketoacyl-CoA (EC 2.3.1.9): 3- 2.3.1.9): 3-ketoacyl-CoA type II (EC : Beta- deoxyphosphogluconate 1-pyrroline-5- zinc containing (EC 3.1.3.5): 5-nucleotidase : Enoyl-[acyl-carrier- : Enoyl-[acyl-carrier- Glutathione (EC 2.1.1.31): tRNA putative histidinol C-terminal synthase small 3-phosphate D-glucopyranose Enoyl-CoA Carbamoyl- beta subunit (EC 4.3.1.17) 1.5.99.1): Sarcosine beta subunit (EC glutamyltranspeptidase (EC 2.3.2.8) : Dipeptidyl (EC 2.3.1.41): large beta chain (EC Branched-chain [NADP+] Histidinol 3-phospho-D-glycerate arg protein CutE: thiolase (EC 2.3.1.16) @ ketoacyl-CoA thiolase thiolase (EC 2.3.1.16) @ Hydrolase (EC 3.8.1.2): galactosidase aldolase (EC carboxylate alcohol dehydrogenase, SurE (EC 3.1.3.5) CDS S-transferase (Guanine37-N1) - dehydrogenase domain PUA: S-ribosyl-L- (S)-2-aceto-2- cys chain (EC 6.3.5.5): L-cysteine biosynthesis I 6-phosphate lys hydratase [isoleucine phosphate dehydrogenase Sarcosine oxidase Long-chain-fatty-acid-- an(EC α-( 2.3.2.2)γ-L- protein] reductase protein] reductase : Arginine- carboxypeptidase 3-oxoacyl-[acyl- subunit (EC amino acid 1-deoxy-D- / L-serine dehydratase, Apolipoprotein N- (EC 2.3.1.16) @ (EC 3.2.1.23) CDS 4.1.2.14): 4-hydroxy-2- domain protein methyltransferase Tryptophan Dihydropyrimidine dehydrogenase homocysteine D-3-phosphoglycerate hydroxybutanoate Arginase/agmatinase/ Cysteine Carbamoyl-phosphate degradation] synthase (EC 1.5.99.1) CDS delta subunit (EC CoA ligase (EC 6.2.1.3) [+ 3 isozymes] [+ 3 isozymes] Hydrolase (EC 3.8.1.2) CDS synthetase: zinc-containing: alcohol β-D-ribosylnicotinate [+ 2 isozymes] [+ 2 isozymes] tRNA-protein Dcp (EC carrier-protein] (but probably not): Acetolactate γ G1RHH-1923 aminotransferase palmitate xylulose 5- alpha subunit (EC urea (4Z,7Z,10Z,13Z,16Z,19Z) leukotriene-D4 glutamyl)-L- XXXG xyloglucan -L-glutamyl (EC 1.1.1.23): formimionoglutamate acyltransferase (EC : Long-chain-fatty- [+ 3 isozymes] D-galactopyranose oxoglutarate aldolase (EC Dihydroneopterin dehydrogenase, [+ 7 isozymes] 1 (EC putative histidinol a cis,cis-delta19 synthase alpha dehydrogenase dehydrogenase desulfurase SAH synthase small chain (EC 4.2.1.17) / 3- small chain 4.3.1.17): G1RHH-2694 Sarcosine Sarcosine oxidase N-methyl-L-proline acetyl-CoA palmitoleoyl-CoA acetyl-CoA amino acid (R)-lactate a (2E)-dodec-2-enoyl-[acp] a (2E)-icos-2-enoyl-[acp] transferase a dipeptide a peptide synthase, an N - synthase 5-phosphate [+ 2 isozymes] phosphate Urease: Urease a 2-acyl-1-lyso- an N-acyl-(S-diacyl-sn-glyceryl) -docosahexaenoyl-CoA (4Z,7Z,10Z,13Z,16Z)- oligosaccharide (glutathion-S-yl)(1H- chain (EC 4.2.1.20): [NADP+] (EC 1.3.1.2) G1RHH-2646 (EC 1.1.1.95): D-3- hydrolase: Arginase/ (EC 2.8.1.7) ser Long-chain-fatty-acid-- Ins(3)P hydroxyacyl-CoA (EC 6.3.5.5) alpha subunit (EC acid--CoA ligase (EC acetyl-CoA pyruvate glyoxylate aldolase (EC zinc-containing (EC 37 dehydrogenase (but 3-oxo-C56:2-[acp small synthase lipoprotein posttranslational modification alpha subunit dehydrogenase (EC an N-terminal L- a 3-oxotetradecanoyl-[acp] methylguanine val phosphoglycerate agmatinase/ L-ornithine : Carbamoyl- phosphatidylethanolamine -L-cysteinyl-[lipoprotein] docosapentaenoyl-CoA 4.1.2.25) / indol-3-yl)acetonitrile Tryptophan synthase Gamma- : Dihydropyrimidine , SufS carbamoyl phosphate Serine CoA ligase (EC 6.2.1.3) Histidyl-tRNA dehydrogenase 2-aminoprop-2-enoate 1.5.99.1): Sarcosine Sarcosine oxidase Probable N- D-xylopyranose Arg in tRNA subunit (EC (EC 2.2.1.7) (EC 3.5.1.5) arginiyl-3-sulfino- a tRNA his alpha chain (EC glutamyl dehydrogenase his dehydrogenase (EC (R)-2,3-dihydroxy- formimionoglutamate subfamily: Adenosylhomocysteinase acetyltransferase : Long-chain-fatty- Inositol-1- (EC 1.1.1.35) / 3- phosphate gamma subunit (EC AMP diphosphate 18-hydroxyoleoyl-CoA 6-(hydroxymethyl) : 1-deoxy-D- synthetase CDS Urease dehydrogenase methylproline glycolaldehyde L-alanyl-[protein] (S)-2-aceto-2- Valine--pyruvate L-homocysteine 3-methylpentanoate a [prolipoprotein]-L-cysteine synthase -7,8-dihydropterin phosphate [NADP+] [+ 3 isozymes] Arginase Cysteine (EC 3.3.1.1): (EC 2.3.1.30): Serine acid--CoA ligase (EC monophosphatase (EC 6.1.1.21): hydroxybutyryl-CoA beta subunit (EC (EC 1.5.99.1) CDS demethylase hydroxybutanoate xylulose 5- [+ 2 isozymes] ser indole reductase aminotransferase 3-phosphooxypyruvate Dihydroxy-acid (EC 3.5.3.1): desulfurase Adenosylhomocysteinase acetyltransferase (EC 3.1.3.25): Histidyl-tRNA epimerase (EC small chain (EC 1.-.-.-): 5,6-dihydrouracil Long-chain-fatty-acid-- phosphate his Prolipoprotein 3.5.1.5) CDS Ketol-acid (EC 1.2.1.41): (EC 2.6.1.66): dehydratase G1RHH-1884 (EC 2.8.1.7) (EC 3.3.1.1) CDS ser (EC 2.3.1.30) G1RHH-1874 synthetase 5.1.2.3): Enoyl-CoA gly Probable N- CoA ligase (EC 6.2.1.3) Urease gamma N-acetyl-muramoyl-(L- 46 37 Phosphoserine synthase diacylglyceryl transferase carbamate 2-iminopropanoate 3-(4-hydroxyphenyl)- adenosylcobinamide- phenyl ribotide XLLG xyloglucan a [protein]-L-glutamate- an N-terminal a guanine guanine reductoisomerase Tryptophan synthase G1RHH-1922 Valine--pyruvate (EC 4.2.1.9): L-ornithine , SufS O-acetyl-L-serine (EC 6.1.1.21) hydratase [isoleucine methylproline a peptidoglycan 7-hydroxylaurate 3-oxo-(9Z)-octadecenoyl-CoA 3-oxopentanoyl-CoA a 5-L-glutamyl- an L-phenylalanyl- an N-terminal (S)-4-hydroxymandelate glycerophosphoserine an L-arginyl- 5-methylcytosine a cis,cis-delta15,3 Hydantoinase/ : Long-chain-fatty- Inositol-1- (EC 2.4.99.-): Prolipoprotein subunit (EC an amino acid oligosaccharide 5 alanyl-γ-D-glutamyl-L- a type IV prepilin a hexanoyl-[acp] 3-sulfo-L- Phe L-threo-3-phenylserine aminotransferase aminotransferase (EC 1-deoxy-D-xylulose His 3-oxo-propanoyl-CoA GDP phosphate O -methyl-ester [tRNA Phe ] arginyl-[protein] [tRNA Arg ] in tRNA in tRNA hydroxy C52:2-[ac (EC 1.1.1.86) beta chain (EC 4.2.1.20) oxoprolinase ammonia assimilation cycle III Dihydroxy-acid Ornithine acid--CoA ligase (EC monophosphatase an L-histidyl-[tRNA ] 3.5.1.5) CDS demethylase Lysozyme (EC [peptide] Beta- L-glutamate-5- 2.6.1.52): Phosphoserine Cysteine L-homocysteine Cysteine diacylglyceryl transferase [+ 4 isozymes] Long-chain-fatty-acid-- 3-ketoacyl-CoA thiolase 3-ketoacyl-CoA thiolase 3-ketoacyl-CoA thiolase Gamma- Cobalamin Chemotaxis lysyl-D-alanyl-D-alanine) mandelate racemase/ Enoyl-[acyl-carrier- Glycerophosphoryl alanyl-[protein] tRNA (guanine46-N7- Cytosine deaminase tRNA : Ketol-acid (EC L-cystathionine 5-phosphate His Leucyl/ D-alanyl-D-alanine Leader peptidase Arginine- Low-specificity : Tryptophan synthase family protein: dehydratase carbamoyltransferase (EC 3.1.3.25) a tRNA (EC 3.2.1.17): Lysozyme (EC 2.3.1.16) @ Acetyl- (EC 2.3.1.16) @ Acetyl- galactosidase muconate lactonizing diester semialdehyde aminotransferase (EC desulfurase synthase: Cysteine a [prolipoprotein]-S-1,2- (3R)-7-carboxy-3-hydroxy-4- ammonium CoA ligase (EC 6.2.1.3) (EC 2.3.1.16) @ Acetyl- glutamyltranspeptidase synthase response regulator phenylalanyl- carboxypeptidase (Prepilin peptidase) protein] reductase )-methyltransferase (EC 3.5.4.1): (Guanine37-N1) - L-threonine reductoisomerase beta chain (EC (EC 4.2.1.9) (EC 2.1.3.3): Ornithine palmitoyl-CoA 1-deoxy-D-xylulose (EC 3.2.1.17) CDS (EC 3.2.1.23) tRNA-protein Hydantoinase/ ammonium (EC 2.8.1.7) synthase CDS : Inositol-1- methyl-5-oxoheptanoyl-CoA : Long-chain-fatty- CoA acetyltransferase (EC CoA acetyltransferase CoA acetyltransferase (EC (EC 2.3.2.2): Gamma- (EC 2.7.8.26): protein-glutamate enzyme family protein: [NADH] (EC 1.3.1.9) phosphodiesterase (EC 2.1.1.33): tRNA Cytosine deaminase methyltransferase (EC 1.1.1.86) ala glu O-acetylhomoserine Phosphoserine diacyl-sn-glyceryl-L-cysteine pro tRNA--protein (EC 3.4.16.4): D- (EC 3.4.23.43) / N- transferase aldolase (EC Tryptophan oxoprolinase (S)-3-methyl-2- : Cysteine carbamoyltransferase 5-phosphate monophosphatase CO pyruvate Phage lysin (EC 3.2.1.17) acid--CoA ligase (EC 2.3.1.9): 3-ketoacyl-CoA (EC 2.3.1.9): 3- 2.3.1.9): 3-ketoacyl-CoA G1RHH-2708 : Beta- methylesterase mandelate racemase/ (EC 3.1.4.46): (guanine46-N7-)- (EC 3.5.4.1) CDS (EC 2.1.1.31): tRNA Glutamine synthetase sulfhydrylase aminotransferase (EC L-glutamate-5- Cysteine synthase Enoyl-CoA 2 glutamyltranspeptidase transferase alanyl-D-alanine methyltransferase : Enoyl-[acyl-carrier- (EC 2.3.2.8) 4.1.2.48): Low- (R)-2,3-dihydroxy- synthase alpha family protein oxopentanoate desulfurase (EC Nucleoside and Nucleotide Biosynthesis reductoisomerase (EC 3.1.3.25) # Phage lysozyme thiolase (EC 2.3.1.16) @ ketoacyl-CoA thiolase thiolase (EC 2.3.1.16) @ phenyl-Coβ- galactosidase CheB (EC 3.1.1.61) muconate lactonizing Glycerophosphoryl methyltransferase (Guanine37-N1) - Alanine type I (EC 6.3.1.2): (EC 2.5.1.49) / O- 2.6.1.52): G1RHH-2557 semialdehyde (EC 2.5.1.47): Lipoprotein signal hydratase [isoleucine Long-chain-fatty-acid-- an α(EC-(5-L- 2.3.2.2) (EC 2.3.2.6) carboxypeptidase (EC 2.1.1.-): protein] reductase : Arginine- Cytosine deaminase specificity 3-methylpentanoate chain (EC 4.2.1.20): (S)-1-pyrroline- Branched-chain (EC 2.8.1.7) (EC 1.1.1.267): 1- Glycyl-tRNA or muramidase (EC (EC 2.3.1.16) @ GMP adenosylcobamide (EC 3.2.1.23) CDS : Chemotaxis diester (EC methyltransferase racemase Dihydropyrimidinase Glutamine synthetase succinylhomoserine Cysteine synthase peptidase (EC degradation] Detoxification CoA ligase (EC 6.2.1.3) [+ 3 isozymes] [+ 3 isozymes] a peptide glutamyl)- : Leucyl/ (EC (R)-4-hydroxymandelate G1RHH-516 [+ 2 isozymes] tRNA-protein an N 7 - (EC 3.5.4.1): L-threonine deoxy-D-xylulose myo-inositol 3.2.1.17): G1RHH-1032 5'-phosphate XXXG xyloglucan Dihydroxy-acid Tryptophan synthase 5-carboxylate amino acid Proline CDS L-cystathionine superpathway of purine nucleotides de novo biosynthesis I synthetase: 3.4.23.36): Lipoprotein : Long-chain-fatty- acetyl-CoA (7Z)-hexadecenoyl-CoA [+ 3 isozymes] propanoyl-CoA acetyl-CoA D-galactopyranose response regulator a cleaved type sn-glycerol 46 1 (EC a cis,cis-delta15 (EC 5.1.1.1) (EC 3.5.2.2): type I (EC 6.3.1.2) sulfhydrylase 3-phospho-L-serine (EC 2.5.1.47) CDS superpathway of guanosine superpathway of guanine and CMP phosphorylation (EC 4.2.1.17) / 3- amino acid oligosaccharide phenylalanyl- N-acetyl-muramoyl-(L-[+ 2 isozymes] a peptide a (2E)-hex-2-enoyl-[acp] ser transferase methylguanine Cytosine deaminase an N - aldolase (EC dehydratase alpha chain (EC aminotransferase dehydrogenase adenine and 5-phosphate Glycyl-tRNA a N-acetylmuramoyl-pentapeptide- 3-phosphate Pyrroline-5- : Alanine Dihydropyrimidinase Glutamine synthetase ala signal peptidase (EC hydroxyacyl-CoA N-acetyl-D-glucosamine acid--CoA ligase (EC acetyl-CoA 4-hydroxybenzoyl-CoA MeOH a [protein]-α-L-glutamate tRNA--protein IV prepilin (EC in tRNA (EC 3.5.4.1) CDS 37 3-oxo-C52:2-[acp (EC 2.5.1.48): nucleotides de novo biosynthesis I adenosine salvage III adenosine nucleotides guanosine salvage Secondary Metabolite Degradation superoxide diphosphoundecaprenol D-ala alanyl-γ-D-glutamyl- an N-terminal L- methylguanine gly benzaldehyde (EC 4.2.1.9): racemase (EC 3.5.2.2) CDS Phosphoserine (EC 2.6.1.42): (EC 1.5.99.8) cys synthetase triclosan resistance L-phenylalanyl-L- Phe carboxylate type I (EC 6.3.1.2): G1RHH-2713 PRPP de novo biosynthesis I CMP dehydrogenase arsenate phenylmercury acetate degradation arginine a tRNA Phe L-lysyl-D-alanine) Arg thymine in tRNA MEP alpha chain (EC radicals AMP diphosphate 7-hydroxylauroyl-CoA arginiyl-3-sulfo- a tRNA Dihydroxy-acid trp reductase (EC 5.1.1.1) Glutamine synthetase phosphatase (EC Branched-chain (Proline oxidase) / Cystathionine gamma- Cytidylate kinase (EC an (S-diacyl-sn-glyceryl)-L- (EC 1.1.1.35) / 3- dependent arginyl-[protein] 3-ureidopropanoate a lipoprotein signal peptide degradation detoxification L-alanyl-[protein] dehydratase O-acetylhomoserine amino acid Delta-1-pyrroline- lyase (EC 4.4.1.1): L-citrulline Amidophosphoribosyltransferase IMP guanosine Glycyl-tRNA cysteinyl-[apolipoprotein] myo-, chiro- and scyllo-inositol degradation (EC 1.5.1.2) CDS type I (EC 6.3.1.2) 3.1.3.3): Phosphoserine adenine IMP asp 2.7.4.25): Cytidylate gly hydroxybutyryl-CoA N-acetylglucosamine D-sorbitol II (glutaredoxin) a trans-2-enoyl- acid resistance (EC 4.2.1.9) sulfhydrylase aminotransferase 5-carboxylate Cystathionine gamma- 2-C-methyl-D- synthetase superpathway of mercuriphenyl acetate : Pyrroline-5- gln phosphatase (EC 3.1.3.3) (EC 2.4.2.14): Purine nucleoside kinase (EC 2.7.4.25) CDS epimerase (EC degradation II superoxide [acyl-carrier protein] Alanine Beta- Purine nucleoside Adenylosuccinate erythritol 4-phosphate Apolipoprotein N- degradation II D-glucarate and D- arsenate reactive oxygen species degradation (S)-3-methyl-2- carboxylate (EC 2.5.1.49) / O- [+ 2 isozymes] dehydrogenase L-ornithine degradation lyase (EC 4.4.1.1) Argininosuccinate Amidophosphoribosyltransferase (EC phosphorylase (EC beta chain (EC Superoxide Enoyl-[acyl- arg ureidopropionase Inosine-5'- phosphorylase (EC CDP Gly acyltransferase (EC 5.1.2.3): Enoyl-CoA 1D-chiro-inositol racemase succinylhomoserine ser (EC 1.5.1.12) synthetase (EC cytidylyltransferase a glycyl-[tRNA ] N-acetyl-D- D-sorbitol galactarate degradation carrier-protein] 3-oxo-2-(cis-2'-pentenyl)- all-trans- XLXG xyloglucan a [disulfide- an N 3 -methyladenine adenine 1518 / a long-chain a dipetide with an N- oxopentanoate reductase (EC Glutamate synthase I (L-proline biosynthesis) synthase (EC 6.3.4.5) gly 2.4.2.1): Purine nucleoside hydratase [isoleucine dismutase Arsenate Biosynthetic an oxidized ferredoxin 3-oxo-(7Z)-hexadecenoyl-CoA a lipid II indolylmethylisothiocyanate glutathione a proteinogenic a protein with glycerol glycerophosphoglycerol ADP-D-ribose 5-fluorocytosine hydroxypyruvaldehyde a cis,cis-delta13,3 (EC 5.1.1.1) (EC 3.5.1.6): Beta- β monophosphate 2.4.2.1): Purine nucleoside 2.3.1.-) / Copper dihydrolipoamide 1519 5-phospho- -D-ribosylamine 6.3.4.4): G1RHH-2690 Nucleoside diphosphate (EC 2.7.7.60) / 2-C- Gly myo-inositol glucosamine 6-phosphate reductase glu cyclopentane-1-(3-oxohexanoyl)-CoA glutathione hexaprenyl 4-hydroxybenzoate oligosaccharide bond carrier in DNA adenine in 16S rRNA a decanoyl-[acp] aldehyde terminal L-aspartate [NADPH]: Glutamate sulfhydrylase ile : Proline : Argininosuccinate phosphorylase (EC a tRNA N-acetylglucosamine D-galactarate D-glucarate [Fe] (EC reductase superoxide arginine [iron-sulfur] cluster amino acid reduced L- phosphate hydroxy C50:2-[ac Branched-chain Pyrroline-5- ## horizontal ureidopropionase (2Z)-2-aminobut-2-enoate cys dehydrogenase phosphorylase (EC adenylo-succinate kinase (EC 2.7.4.6): methyl-D-erythritol homeostasis protein a peptide Sorbitol-6- 3-ketoacyl-CoA thiolase 3-ketoacyl-CoA thiolase D-alanyl-D-alanine Glutathione S- diphosphate Beta- protein] carrying Alcohol dehydrogenase, Dihydrolipoamide DNA-3- SSU rRNA Glycerophosphoryl Tellurite resistance Alkanal Microsomal (EC 2.5.1.48): O- Serine dehydrogenase synthase (EC 6.3.4.5) 3-hydroxyacyl-CoA Myo-inositol 2- 1.15.1.1): (EC 1.20.4.1) [NADH] (EC decarboxylase Ferredoxin- Gamma- 4-hydroxybenzoate cysteine residues Enoyl-[acyl-carrier- Cytosine deaminase Aldehyde amino acid transfer: (EC 3.5.1.6) CDS synthase [NADPH] L-ornithine (EC 1.1.1.205) Purine nucleoside CutE: Apolipoprotein kinase of eukaryotic phosphate 2- carboxypeptidase galactosidase protein disulfide zinc containing (EC 1.1.1.1) protein TrgB carboxylate acetylhomoserine hydroxymethyltransferase (EC 1.5.99.8) Purine nucleoside Nucleoside diphosphate 2,4-cyclodiphosphate dehydrogenase ; ArsR family Superoxide dismutase 2+ benzene acetate 1.3.1.9): Enoyl- (EC 2.3.1.16) @ Acetyl- (EC 2.3.1.16) @ Acetyl- transferase domain glutamyltranspeptidase a disulfide bond acetyltransferase methyladenine (adenine(1518)-N(6)/ protein] reductase diester monooxygenase (EC 3.5.4.1): dipeptidase aminotransferase putative GlxC Glutamate Phosphoribosylamine- : Inosine-5'- Adenylosuccinate phosphorylase (EC N-acyltransferase (EC dehydrogenase type (EC 2.7.1.59): Superoxide Hg (EC 4.1.1.19): dependent glutamate polyprenyltransferase oxidoreductase: dehydrogenase reductase Alanine Ornithine L-arginino-succinate phosphorylase (EC kinase (EC 2.7.4.6) synthase (EC dehydrogenase [Fe] (EC 1.15.1.1): CoA acetyltransferase (EC CoA acetyltransferase (EC (EC 3.4.16.4): D- protein: Glutathione (EC 3.2.1.23) : Alcohol dehydrogenase, component of pyruvate glycosylase adenine(1519)-N(6))- [NADH] (EC 1.3.1.9) phosphodiesterase / ADP-ribose alpha chain (EC precursor sulfhydrylase (EC (EC 2.1.2.1): Serine lyase (EC 4.3.2.2): (EC 1.1.1.35): 3- 1-keto-D-chiro-inositol (EC 1.1.1.18): dismutase transcriptional [acyl-carrier- G1RHH-2085 synthase (EC (EC 2.3.2.2): Gamma- (EC 2.5.1.39): 4- Cytosine deaminase (EC 1.2.1.3) (EC 2.6.1.42): racemase β-alanine synthase [NADPH] cyclodeaminase -glycine ligase monophosphate 2.4.2.1): Purine nucleoside 2.4.2.1): Purine nucleoside an N-acyl-(S-diacyl-sn-glyceryl) N-acetylglucosamine (EC 1.1.1.140) 2.3.1.9): 3-ketoacyl-CoA 2.3.1.9): 3-ketoacyl-CoA alanyl-D-alanine S-transferase : Beta- Periplasmic zinc containing (EC dehydrogenase (EC 3.2.2.20): dimethyltransferase (EC 3.1.4.46): pyrophosphatase 1.14.14.3): Alkanal (EC 3.4.13.19) (EC 1.5.1.2) hydroxymethyltransferase (EC glu 4.6.1.12): 2-C- hydroxyacyl-CoA Myo-inositol 2- regulator: Superoxide dismutase Mercuric ion protein] reductase agmatine 1.4.7.1): Ferredoxin- glutamyltranspeptidase hydroxybenzoate : Enoyl-[acyl-carrier- (EC 3.5.4.1) CDS : Aldehyde Branched-chain large chain (EC (EC 4.3.1.12) Argininosuccinate (EC 6.3.4.13): dehydrogenase Adenylosuccinate phosphorylase (EC CTP Methionyl-tRNA Inosose kinase of eukaryotic : Sorbitol-6- [Fe] (EC carboxypeptidase (EC thiol:disulfide (EC 3.6.1.13): : Pyrroline-5- (EC 5.1.1.1) ## cys phosphorylase (EC methyl-D-erythritol -L-cysteinyl-[lipoprotein] dehydrogenase (EC 5-dehydro-4- [Fe] (EC 1.15.1.1) reductase (EC thiolase (EC 2.3.1.16) @ thiolase (EC 2.3.1.16) @ domain protein (EC 2.3.2.2) galactosidase alcohol dehydrogenase, complex (EC 2.3.1.12) G1RHH-2637 (EC 2.1.1.182) protein] reductase Glycerophosphoryl monooxygenase : Microsomal 2-iminobutanoate Phosphoribosylamine- lyase (EC 4.3.2.2) CDS guanine synthetase isomerase dehydrogenase 1.15.1.1) Arsenate [+ 2 isozymes] dependent an α-(γ-L- polyprenyltransferase ainterchange [disulfide-bond Cytosine deaminase dehydrogenase amino acid carboxylate [+ 9 isozymes] gly : Ornithine lyase (EC 4.3.2.1): (EC adenosine 4-phosphate N-acetylglucosamine phosphate 2- hydrogen 1.16.1.1): Mercuric a 2,3,4-saturated [+ 2 isozymes] 3-hexaprenyl-4- (EC 3.2.1.23) CDS zinc-containing: alcohol : Dihydrolipoamide an apurinic site : SSU rRNA diester Tellurite resistance alpha chain (EC dipeptidase 7-carboxy-4-methyl-3,5- (EC 1.1.1.18) scyllo-inositol deoxy-D-glucarate reductase (EC glutamate synthase [+ 3 isozymes] [+ 3 isozymes] [+ 7 isozymes] a protein with carrier protein] 3-methyladenine N 6 -dimethyladenine 1518 [+ 2 isozymes] (EC 3.5.4.1): (EC 1.2.1.3) CDS aminotransferase D-ala cyclodeaminase Argininosuccinate -glycine ligase (EC (EC 6.1.1.10): (EC 5.3.99.-): kinase of eukaryotic dehydrogenase hydrogen peroxide 3-oxo-2-(cis-2'-pentenyl)- a N-acetylglucosamine--N- indol-3-ylmethylisothiocyanate- L-cysteinylglycine glutamyl)-L- XXXG xyloglucan within DNA sn-glycerol protein TrgB / a long-chain reductase (EC Inosine-5'- 4-(cytidine 5'- peroxide ion reductase fatty acyl-[acp] a reduced ferredoxin hydroxybenzoate D-galactopyranose dehydrogenase, acetyltransferase 6 1519 ν precursor (EC a cis,cis-delta13 glu Methionyl-tRNA dioxoheptanoyl-CoA G1RHH-1812 [+ 3 isozymes] 1.20.4.1) ; ArsR H + gln 2-oxoglutarate acetyl-CoA acetyl-CoA (5Z)-tetradecenoyl-CoA D-ala acetylmuramyl-(tetrapeptide) amino acid oligosaccharide a disulfide bond with reduced L- /N -dimethyladenine a (2E)-dec-2-enoyl-[acp] glycerol h Cytosine deaminase [+ 5 isozymes] [+ 2 isozymes] (EC 4.3.1.12) lyase (EC 4.3.2.1) CDS tRNA-specific adenosine- AMP Xanthine-guanine diphospho)-2-C- type (EC 2.7.1.59): (EC (EC 1.16.1.1) CDS cyclopentane-1-butanoyl-CoA glutathione 3-phosphate fatty acid a proteinogenic monophosphate adenine salvage met keto-D-fructose Catalase [iron-sulfur] cluster cysteine residues zinc-containing S-acetyldihydrolipoamide in 16S rRNA D-ribofuranose (EC 3.5.4.1) CDS 3-oxo-C50:2-[acp phosphoribosyltransferase synthetase N-acetylglucosamine [+ 2 isozymes] pyrophosphoryl-undecaprenol 3-phosphooxypyruvate asp pro [+ 2 isozymes] GAR dehydrogenase 34 deaminase (EC 3.5.4.-) methyl-D-erythritol queuosine biosynthesis 6-phosphate Catalase (EC 1.11.1.6) AMP amino acid (EC 6.1.1.10) (EC 1.11.1.6) arsenite 0 L-glyceraldehyde 5-phosphate 5-fluorouracil ile pro arg Adenylate kinase (EC (EC 2.4.2.22): 4-diphosphocytidyl- an L-methionyl- 3-ketoacyl-CoA kinase of eukaryotic Hg ammonium (EC 1.1.1.205) : tRNA-specific adenosine- N-acetyl-D- tartronate semialdehyde / Peroxidase / Peroxidase (EC Xanthine-guanine [initiator tRNA Met ] thiolase (EC 2.3.1.16) Phosphoribosylglycinamide : Inosine-5'- 34 deaminase (EC 2.7.4.3): Adenylate 2-C-methyl-D- 1.11.1.7): G1RHH-2295 adenine Met preQ scyllo-inosose superpathway of β-D- glucosamine (EC 1.11.1.7) formyltransferase (EC 2.1.2.2) kinase (EC 2.7.4.3) CDS phosphoribosyltransferase erythritol kinase initiator tRNA 0 @ Acetyl-CoA H O hydroxyl radical monophosphate Adenosine deaminase glucuronosides degradation 6-phosphate 2-hydroxy-3- : G1RHH- 2 : Phosphoribosylglycinamide acetyltransferase UDP-N-acetyl-α-D-muramoyl-L- a [lysine-biosynthesis-protein all-trans- 3-benzyl-3,6-dihydroxy- 9 dehydrogenase (EC 3.5.4.4): Adenosine Hypoxanthine-guanine (EC 2.7.1.148): 4- Inosose oxopropionate 3-oxo-2-(cis-2'-pentenyl)- a 2'-deoxyribonucleoside (3R,7Z,10Z,13Z,16Z)-3- a guanine (EC 2.3.1.9): 3- N-acetylglucosamine- 2295 O 3-oxo-(9Z)-hexadecenoyl-CoA γ 2,3,6-trichlorohydroquinone glutathione γ Asx urea-1-carboxylate [DNA] acetoacetyl-CoA glycolate 2-oleoylglycerol a peptide with an glutathione fenclorim 4-acetamidobutanal a cis,cis-delta11,2 ADP phosphoribosyltransferase diphosphocytidyl- 2 a single stranded DNA a ribonucleoside triphosphate cyclopentane-1-(3-oxooctanoyl)-CoA alanyl- -D-glutamyl-meso-2,6- LysW]-C-terminal- -(L-glutamate heptaprenyl 4-hydroxybenzoate a tRNA asp 6-(hydroxymethyl) glutathione an octanoyl-[acp] FGAR (EC deaminase (EC 3.5.4.4) CDS dehydratase a β-D-glucuronoside reductase arsenite 5'-triphosphate hydroxydocosatetraenoyl-CoA N-terminal L-proline in tRNA hydroxy C48:2-[ac Adenine Adenine deaminase preQ ketoacyl-CoA 6-phosphate 3-ketoacyl-CoA thiolase 3-ketoacyl-CoA thiolase diaminopimeloyl-D-alanyl-D-alanine Glutathione S- 5-semialdehyde-2-yl)-L-glutamate diphosphate Allophanate hydrolase 2: -diketopiperazine 3-hydroxybutyryl- (EC 2.4.2.8): 2-C-methyl- 1 (EC 1.1.1.60) O DNA primase (EC D-alanyl-D-alanine N-acetyl-gamma- 4-hydroxybenzoate Aspartyl-tRNA synthetase Glutathione Retron-type RNA- Glyoxylate reductase Enoyl-[acyl-carrier- Lysophospholipase Acetoacetyl- Proline Glutathione Aldehyde tRNA (EC 4.2.1.44) deacetylase 2 Ribonucleotide reductase Hypoxanthine-guanine phosphoribosyltransferase (EC 3.5.4.2): Adenine D-erythritol thiolase (EC 2.7.7.-): DNA primase (EC 2.3.1.16) @ Acetyl- (EC 2.3.1.16) @ Acetyl- transferase domain glutamyl-phosphate (EC 6.1.1.12) @ Aspartyl- Allophanate hydrolase 2 S-transferase directed DNA CoA dehydrogenase (EC 1.1.1.79) / Glyoxylate protein] reductase (EC 3.1.1.5); CoA reductase S-transferase dehydrogenase (Guanine37-N1) - Phosphoribosylformylglycinamidine XMP inosine tRNA-guanine : Inosose (EC 3.5.1.25): : 2-hydroxy-3- carboxypeptidase polyprenyltransferase iminopeptidase (EC of class II (coenzyme (EC 2.4.2.7): Adenine deaminase (EC 3.5.4.2) CDS 2-phospho-4-(cytidine 2.3.1.16) @ (EC 2.7.7.-) CDS CoA acetyltransferase (EC CoA acetyltransferase (EC protein: Glutathione reductase (EC 1.2.1.38) tRNA(Asn) synthetase (EC subunit 2 (EC Allophanate domain protein: polymerase (EC (EC 1.1.1.157): 3- reductase (EC 1.1.1.26) / [NADH] (EC 1.3.1.9) Monoglyceride lipase (EC 1.1.1.36) domain protein: (EC 1.2.1.3) methyltransferase peptidoglycan biosynthesis I (meso-diaminopimelate containing) Cell Structure Biosynthesis synthase: transglycosylase (EC dehydratase (EC D-glucopyranuronate G1RHH-2599 oxopropionate (EC 3.4.16.4): D- (EC 2.5.1.39): 4- 3.4.11.5): Proline peptidoglycan maturation (meso-diaminopimelate containing) phosphoribosyltransferase (EC 5'-diphospho)-2-C- [+ 3 isozymes] 2.3.1.9): 3-ketoacyl-CoA 2.3.1.9): 3-ketoacyl-CoA S-transferase hydrolase 2 subunit 1 (EC hydroxybutyryl-CoA Hydroxypyruvate reductase (EC 3.1.1.23); putative: of ethylmalonyl- Glutathione : Aldehyde (EC 2.1.1.31): tRNA cellulose Phosphoribosylformylglycinamidine Purine nucleoside B12-dependent) (EC GMP 2.4.2.29): tRNA-guanine 4.2.1.44) CDS reductase (EC DNA primase (EC alanyl-D-alanine : N-acetyl-gamma- hydroxybenzoate 6.1.1.23): Aspartyl-tRNA Glutathione 2.7.7.49): Retron- : Enoyl-[acyl-carrier- iminopeptidase GMP synthase thiolase (EC 2.3.1.16) @ thiolase (EC 2.3.1.16) @ domain protein dehydrogenase (EC (EC 1.1.1.81): Glyoxylate Lysophospholipase S-transferase (Guanine37-N1) - UDP-N-acetyl- biosynthesis Phosphoribosylformylglycinamidine 1.17.4.1): Ribonucleotide methyl-D-erythritol 3D-(3,5/4)- N-acetylglucosamine- 2.7.7.-), phage carboxypeptidase (EC a [lysine-biosynthesis-proteinglutamyl-phosphate polyprenyltransferase synthetase (EC 6.1.1.12) @ Allophanate hydrolase 2: S-transferase type RNA-directed protein] reductase CoA pathway: (EC 3.4.11.5) CDS dehydrogenase α lipid II (meso [glutamine- phosphorylase (EC transglycosylase (EC -D-glucosamine Carbohydrate Biosynthesis reductase of class II hypoxanthine 5-carboxy-2-methyl- 6-phosphate (R)-glycerate Carbohydrate Degradation [+ 3 isozymes] [+ 3 isozymes] [+ 7 isozymes] 3-heptaprenyl-4- Asx G1RHH-2289 G1RHH-2290 domain protein DNA polymerase reductase (EC 1.1.1.79) / (EC 3.1.1.5); Acetoacetyl- domain protein (EC 1.2.1.3) CDS methyltransferase diaminopimelate containing) Metabolic Regulator Biosynthesis Phosphoribosylformylglycinamidine 2.4.2.1): Purine nucleoside 2-C-methyl-D- acetyl-CoA trihydroxycyclohexane- related: G1RHH-3753 UDP-N-acetylmuramoyl-L-[+ 2 isozymes] LysW]-C-terminal-γ-(5-phospho- an L-aspartyl-[tRNA ] (S)-3-hydroxybutanoyl-CoA [+ 2 isozymes] a peptide pro cellulose hydrolyzing] a 7-aminomethyl-7- deacetylase 3-oxo-2-(cis-2'-pentenyl)- 2,6-dichloro-3-(glutathion- hydroxybenzoate (EC UDP-N-acetylglucosamine AMP erythritol 4-phosphate 3-oxopentanoyl-CoA acetyl-CoA (7Z)-tetradecenoyl-CoA acetyl-CoA CO ammonium glyoxylate oleate glycerol CoA reductase [+ 7 isozymes] [+ 5 isozymes] 1 a cis,cis-delta11 synthase, synthetase phosphorylase (EC Ribonucleotide reductase 34 1,2-dione ssDNA/pppN(pN) hybrid D-ala alanyl-γ-D-glutamyl-meso-2,6- L-glutamyl)-L-glutamate 2 3-benzyl-3,6 -bis(glutathione)[+ 7 isozymes] [DNA] a (2E)-oct-2-enoyl-[acp] an N - Cellulose Monofunctional (EC 6.3.5.2): deazaguanosine in tRNA aldehydo-D-glucuronate (EC 3.5.1.25): N- D-glycerate n -1 cyclopentane-1-hexanoyl-CoA S-yl)-hydroquinone 1-carboxyvinyltransferase gluconeogenesis I of class II (coenzyme Xanthine-guanine cytidylyltransferase superpathway of glucose and xylose degradation (EC 1.1.1.36) of 4-(glutathion-S-yl)-fenclorim 4-acetamidobutanoate 9 3-oxo-C48:2-[acp O-antigen building blocks biosynthesis (E. coli) ppGpp biosynthesis subunit (EC 6.3.5.3): GMP synthase 3D-(3,5/4)- diaminopimeloyl-D-alanine - 6-(hydroxymethyl) methylguanine (EC 2.5.1.7): G1RHH-2649 synthase biosynthetic Purine nucleoside phosphoribosyltransferase S-adenosylmethionine:tRNA acetylglucosamine- 2-kinase (EC D-galactose degradation I (Leloir pathway) lactose (7Z,10Z,13Z,16Z)-3- mannosylglycerate Phosphoribosylformylglycinamidine B12-dependent) (EC (EC 2.7.7.60) / 2-C- trihydroxycyclohexane- Uronate isomerase -diketopiperazine in tRNA [glutamine- phosphorylase (EC ribosyltransferase- oxodocosatetraenoyl-CoA UDP-N-acetyl-α- (UDP-forming) peptidoglycan α biosynthesis I (EC 2.4.2.22): (EC 5.3.1.12): 6-phosphate 2.7.1.-): D- D-glucopyranose degradation II (S)-malate UDP- -D- α-D- D-glucopyranose hydrolyzing] (EC 1.17.4.1): Ribonucleotide methyl-D-erythritol 1,2-dione hydrolase: D-glucosamine- (EC 2.4.1.12) transglycosylase pppGpp 2.4.2.1): Purine nucleoside Xanthine-guanine isomerase (EC 5.-.-.-): S- D-glucosamine glycerate 2- 6-phosphate β-D-galactopyranose galactose glucopyranose 6-phosphate GTP pyrophosphokinase GDP-α-D- FGAM reductase of class II 2,4-cyclodiphosphate succinyl-CoA propanoyl-CoA Epi-inositol hydrolase Uronate isomerase : G1RHH-2617 (EC 2.4.2.-): phosphorylase (EC phosphoribosyltransferase adenosylmethionine:tRNA kinase (EC α-lactose enolpyruvate 1-phosphate Glucose-6- mannose synthase (EC (EC 3.7.1.-) CDS (EC 5.3.1.12) CDS 6-phosphate Glucose-6- (EC 2.7.6.5), (p)ppGpp Aldose 1- all-trans- a [lysine-biosynthesis- 34 967 cellulose Monofunctional Glucose-1-phosphate Phosphoribosylformylglycinamidine GMP pyrimidine Alcohol Degradation 2.7.1.-) CDS an L-methionyl- a 2'-deoxyribonucleoside 1-carboxyvinyl 1-carboxyvinyl a dipeptide with a a guanine 1-oleoyl- a cytosine UDP-N- phosphate synthetase II / Guanosine- dADP Hypoxanthine-guanine 4.6.1.12): 2-C- an epoxyqueuosine 34 in tRNA phosphate 1- an (S)-2-halocarboxylate O-acetyl-L-serine hydrogen selenide (11Z)-3-oxo-hexadecenoyl-CoA a 10- 3-oxooctanoyl-CoA 3,4-dihydroxyphenylglycolaldehyde glyoxylate 3,3',5'-triiodo-L-thyronine queuine a tripeptide biosynthetic UDP-Galf thymidylyltransferase GTP pyrophosphokinase cyclo-ligase (EC 6.3.3.1): hypoxanthine ribonucleosides D-fructuronate epimerase Met glutathione hypoglycin A decaprenyl 4-hydroxybenzoate protein LysW]-C-terminal- [DNA] C-terminal L-proline a 3-oxoicosanoyl-[acp] L-cystathi isomerase α methyl-D-erythritol 5-deoxy-D-glucuronate formyltetrahydrofolate [initiator tRNA ] 5'-triphosphate carboxyphosphonate carboxyphosphonate in tRNA sn-glycerol in 16S rRNA acetylenolpyruvoylglucosamine 3',5'-bis(diphosphate) 3'- (EC 2.7.6.5), (p)ppGpp 2-O-( -D- phosphoribosyltransferase D-galacturonate degradation I 2-phospho-D-glycerate dehydrogenase (EC 5.1.3.3) Haloacid dehalogenase, Cysteine synthase: 3-ketoacyl-CoA thiolase 3-ketoacyl-CoA thiolase diphosphate γ-(L-ornithyl)-L-glutamate Aldehyde carboxyvinyl- carboxyvinyl- Glyoxylate reductase Xaa-Pro Type I tRNA-guanine Peptidase B Lysophospholipase 16S rRNA peptidoglycan (EC 2.7.7.24): Phosphoribosylformylglycinamidine ATP-binding salvage II epoxyqueuosine 3'-ketolactose Methionyl-tRNA Gamma- 4-hydroxybenzoate Acetylornithine DNA polymerase 3-oxoacyl-[acyl- reductase (EC 1.1.1.158): UDP- (EC 5.3.1.9) pyrophosphohydrolase mannosyl)- Nucleoside diphosphate (EC 2.4.2.8): 4-phosphate ethanol degradation II D-mannonate α (EC 1.1.1.49) (EC 2.3.1.16) @ Acetyl- dehydrogenase (EC aminopeptidase G1RHH-1960 synthetase II / Guanosine- Xanthine-guanine cytidine -D-glucosamine : Aldose 1- type II (EC 3.8.1.2): Cysteine synthase CDS (EC 2.3.1.16) @ Acetyl- glutamyltranspeptidase polyprenyltransferase aminotransferase III epsilon subunit carboxyphosphonate carboxyphosphonate (EC 1.1.1.79) / Glyoxylate iodothyronine transglycosylase (EC 3.4.11.23) (EC 3.1.1.5); m(5)C 967 carrier protein] N-acetylenolpyruvoylglucosamine [+ 3 isozymes] dTDP-α-D-glucose : Glucose-6- 3-phospho- protein PhnN; reductase: Iron- glycerol and glycerophosphodiester degradation 5-deoxy- : Glucose-6- formyltransferase (EC 3.1.7.2): GTP 3',5'-bis(diphosphate) 3'- AIR phosphoribosyltransferase kinase (EC 2.7.4.6): Hypoxanthine-guanine 2-C-methyl-D-erythritol- oxidoreductase (EC 6-phosphate aldehydo-D-galacturonate epimerase Beta- Haloacid dehalogenase, Cysteine synthase CoA acetyltransferase (EC CoA acetyltransferase (EC 1.2.1.3): Aldehyde phosphorylmutase, phosphorylmutase, reductase (EC 1.1.1.26) / (EC 3.4.13.9) deiodinase (EC (EC 2.4.2.29): : Peptidase B Monoglyceride methyltransferase a nascent peptidoglycan phosphate Guanylate kinase Cytidine sulfur cluster- glucuronate (EC 2.1.2.9): (EC 2.3.2.2): Gamma- (EC 2.5.1.39): 4- (EC 2.6.1.11): (EC 2.7.7.7): DNA reductase (EC UDP-N- pyrophosphokinase pyrophosphohydrolase D-glycerate Nucleoside diphosphate 2,4-cyclodiphosphate ethanol 1.1.1.57): D-mannonate Uronate isomerase phosphate 1- (EC 5.1.3.3) galactosidase type II (EC 2.3.1.9): 3-ketoacyl-CoA 2.3.1.9): 3-ketoacyl-CoA dehydrogenase putative: carboxyvinyl- putative: carboxyvinyl- Hydroxypyruvate reductase : Xaa-Pro 1.97.1.10): Type tRNA-guanine (EC 3.4.11.23) lipase (EC (EC 2.1.1.-): 16S γ dTDP- (EC 2.7.4.8): (EC 2.4.2.22): deaminase binding protein CDS isomerase (EC Glucosamine- (EC 2.5.1.47): Cysteine Methionyl-tRNA glutamyltranspeptidase hydroxybenzoate Acetylornithine polymerase III 1.1.1.100): with (L-alanyl- -D- isomerase (EC 2.7.6.5), Putative mannosyl- Phosphoribosylaminoimidazole kinase (EC 2.7.4.6) IMP a glycerophosphodiester glycerol oxidoreductase dehydrogenase (EC 3.2.1.23) thiolase (EC 2.3.1.16) @ thiolase (EC 2.3.1.16) @ (EC 1.2.1.3) CDS carboxyphosphonate carboxyphosphonate aminopeptidase CDS acetylenolpyruvoylglucosamine glucose 4,6- (EC 3.1.7.2): GTP ATP-binding Xanthine-guanine (EC 3.5.4.5) Alcohol 6-phosphate (EC 5.3.1.12): CDS Hydrolase (EC 3.8.1.2): synthase (EC 2.5.1.47) CDS formyltransferase (EC 2.3.2.2) polyprenyltransferase aminotransferase (EC epsilon subunit (EC (EC 1.1.1.81): Glyoxylate I iodothyronine transglycosylase 3.1.1.23); putative: rRNA m(5)C 967 G1RHH-1018 glutamyl-meso-2,6- malate (EC 5.3.1.9) 3-phosphoglycerate carboxylase: 1-hydroxy-2- 5.3.1.-): 5-deoxy- D-galactonate degradation (EC a [lysine-biosynthesis-protein 3-(hydroxyphosphinoyl) reductase (EC 1.1.1.158): UDP- pyrophosphokinase phosphoribosyltransferase : Cytidine 34 dehydrogenase Glycerophosphoryl Glycerol (EC 1.1.1.57) Uronate isomerase : Beta- Hydrolase (EC 3.8.1.2) CDS [+ 3 isozymes] [+ 3 isozymes] 3-decaprenyl-4- [+ 5 isozymes] reductase (EC 1.1.1.79) / (EC 3.4.13.9) CDS deiodinase (EC (EC a proteinogenic Lysophospholipase methyltransferase diaminopimeloyl-D-alanyl- dehydratase F6P protein PhnN; methyl-2-(E) a queuosine in tRNA glucuronate deaminase α acetate L-selenocysteine an N-formyl- (EC L-cysteinylglycine hypoglycin B LysW]-C-terminal-γ-(L-glutamate [+ 11 isozymes] carboxyphosphinopyruvate a dipeptide [+ 3 isozymes] N-acetylenolpyruvoylglucosamine dehydrogenase, (EC 2.7.6.5), phosphatase (EC Phosphoribosylaminoimidazole dATP diester (EC 5.3.1.12) CDS 6-phospho -D-galactopyranose galactosidase hydroxybenzoate pyruvate a proteinogenic amino acid (EC 3.1.1.5); (EC (EC 4.2.1.46) Guanylate kinase deaminase (EC 1.1.1.1) kinase (EC isomerase (EC 3.5.99.6): a halide anion an (R)-2-hydroxycarboxylate (9Z)-tetradecenoyl-CoA acetyl-CoA acetyl-CoA hexanoyl-CoA 3,4-dihydroxymandelate glycolate iodide 3,3'-diiodothyronine 34 a (3R)-3- D-alanine) pentapeptide Hypoxanthine-guanine -butenyl 4- D-mannonate L-methionyl- a tetrahydrofolate 5-semialdehyde-2-yl)-L-glutamate [DNA] pro a queuosine 967 2-oxobutanoate ala UDP-N-acetyl- Malate NAD-requiring: 3.1.3.70): Putative carboxylase phosphodiesterase D-tagaturonate D-galactonate D-glucono- (EC 3.2.1.23) amino acid guanine a 5-methylcytosine : dTDP- (EC 3.5.4.5) : Alcohol 2.7.1.30): G1RHH-2598 met glycerol hydroxyicosanoyl-[acp] Glucosamine- Phosphoribosylaminoimidazole phosphoribosyltransferase diphosphate (EC 5.3.1.-) Galactonate dehydratase [initiator tRNA ] in tRNA oleate α-D-muramate D-alanyl-D-alanine dehydrogenase NADP-dependent mannosyl-3- Guanylate kinase (EC 3.1.4.46): Glycerol Mannonate dehydratase 1,5-lactone CDS in 16S rRNA D-alanyl-D-alanine glucose 4,6- -fructose-6- (EC 2.4.2.8): CDS synthase dehydrogenase 5-dehydro-2- glu carboxypeptidase malic enzyme phosphoglycerate carboxylase (EC 2.7.4.8) Glycerophosphoryl F6P (EC 4.2.1.6): Galactonate 6-phosphogluconolactonase 3-keto-β-D- carboxypeptidase (EC 1.1.1.37) dehydratase phosphate GTP ppGpp α Hypoxanthine-guanine uridine (EC 1.1.1.1) CDS kinase (EC (EC 4.2.1.8): Mannonate (EC 1.1.1.40) 2-O-( -D- : Guanylate (EC 1.17.7.1) N-end rule pathway I (prokaryotic) diester deoxy-D-gluconate dehydratase α-D-galactose UDP-N- (EC 3.4.16.4): D- (EC 3.4.16.4): D- : Malate (EC 4.2.1.46) aminotransferase asp CAIR adenine and adenosine salvage I [+ 2 isozymes] 2.7.1.30) CDS dehydratase (EC 3.1.1.31), UDP-α-D-glucose galactose Glutamate superpathway of (Kdo) -lipid A biosynthesis a mature peptidoglycan with mannosyl)- kinase (EC : 1-hydroxy- 5-keto-2- (EC 4.2.1.6) CDS 1-phosphate acetylmuramate- 2 alanyl-D-alanine dehydrogenase Inosine- acetaldehyde (EC 4.2.1.8) CDS eukaryotic type: 6- alanyl-D-alanine γ NADP- [isomerizing] D-altronate 1207 (L-alanyl- -D-glutamyl-meso- dTDP- D-glycerate IMP 2-methyl-2- Leucyl/ all-trans- 34 a [TusE sulfur 3-hexaprenyl- α racemase Nucleoside 2.7.4.8) CDS uridine deoxygluconokinase 2-dehydro-3-deoxy-D-galactonate a [DNA]-3'- a 5'-phospho- + a uridine a guanine a [protein]- - -alanine ligase carboxypeptidase carboxypeptidase (EC 1.1.1.37) CDS dependent (EC 2.6.1.16): GTP pyrophosphokinase phosphogluconolactonase methylmalonate semialdehyde 4-trans-3-oxo-undecenoyl-CoA 3-oxododecanoyl-CoA oxythiamine 3-dimethylsulfoniopropionaldehyde NAD carboxyphosphinopyruvate (S)-lactaldehyde glutathione methylmercury kanamycin B a peptide with an (EC 5.1.1.3) 2,6-diaminopimeloyl-D-alanyl- glucose 4,6- diphosphate (E)-butenyl phenylalanyl- (EC 2.7.1.92): 5-keto- palmitoyl-CoA a ferrocytochrome b a (6S)-5-formyltetrahydrofolate glu nonaprenyl 4-hydroxybenzoate hydroxyl [DNA] carrier protein]-S 4-amino-5- a 3-oxodocosanoyl-[acp] in 16S rRNA L-glutamate (EC 6.3.2.8) a (3R)-3- (EC (EC 2.7.6.5), (p)ppGpp Phosphoribosylaminoimidazole- preferring adenosine Aldehyde 2-dehydro-3-deoxy-D-gluconate Altronate dehydratase (EC 3.1.1.31), 5 H O ATP in tRNA phosphoenolpyruvate dGDP N-terminal L-alanine UDP-N-acetyl- (EC D-alanine) pentapeptide [+ 2 isozymes] malic enzyme dehydratase Glucosamine- (E)-4-hydroxy-3- tRNA--protein 2-dehydro-3- Methylmalonate- 3-ketoacyl-CoA thiolase 3-ketoacyl-CoA thiolase 2 diphosphate Thiaminase II Aldehyde DNA carboxyvinyl- -sulfanylcysteine NADPH-dependent hydroxybenzoate Glutathione Aminoglycoside 6'- Ribosomal RNA Che : Glutamate : UDP-N- hydroxytetradecanoyl-[acp] kinase (EC succinocarboxamide GDP pyrimidine deoxyribonucleotides de novo biosynthesis III nucleoside dehydrogenase 2-deoxygluconokinase (EC 4.2.1.7): Altronate D-galactopyranose Fatty acid desaturase Dihydrofolate synthase 4-hydroxybenzoate tRNA-specific 3-demethylubiquinone- Membrane alanine 3-oxoacyl-[acyl- α [+ 2 isozymes] [+ 2 isozymes] (EC 1.1.1.40) -fructose-6- synthetase II / Guanosine- Purine nucleoside sn-glycerol 3-phosphate D-gluconate Nucleoside triphosphate ligase (EC Pyruvate kinase methylglyoxal reductase N-acetyltransferase: racemase -D-glucosamine (EC 4.2.1.46): 2.7.4.6): GTP pyrophosphokinase methylbut-2-en- transferase (EC 2.7.1.92) 2-dehydro-3- deoxygalactonokinase semialdehyde (EC 1.14.19.1); Delta- (EC 2.3.1.16) @ Acetyl- (EC 2.3.1.16) @ Acetyl- (EC 3.5.99.2) dehydrogenase (EC carboxyphosphonate 2-thiouridylase 9 3-methyltransferase S-transferase aminopeptidase carrier protein] small subunit met acetylmuramate-- 3',5'-bis(diphosphate) 3'- synthase (EC 6.3.2.6): hydrolase phosphorylase (EC (EC 1.2.1.3) ethylene glycol dehydratase 6-phosphate (EC 6.3.2.12) @ pyrophosphohydrolase polyprenyltransferase (EC 2.7.1.40): Aminoglycoside 6'- : NADP- G1RHH-1958 phosphate (EC 2.7.6.5), (p)ppGpp 1-yl diphosphate (EC 2.3.2.6) deoxygluconate kinase (EC 2.7.1.58): 2-dehydro-3- dehydrogenase (EC CoA acetyltransferase (EC CoA acetyltransferase (EC : Thiaminase 1.2.1.3): Aldehyde 6.5.1.2): phosphorylmutase, MnmA: (D-lactaldehyde (EC 2.1.1.64): 3- domain protein: reductase (EC methyltransferase Che (EC 5.1.1.3) alanine ligase (EC Nucleoside pyrophosphohydrolase Phosphoribosylaminoimidazole- UDP CTP (EC 3.2.2.1) 2.4.2.1): Purine nucleoside : Aldehyde Aerobic glycerol- 5-dehydro-2-deoxy-D- (EC 4.2.1.7) CDS 9 fatty acid desaturase Folylpolyglutamate MazG (EC 3.6.1.8): (EC 2.5.1.39): 4- Pyruvate kinase N (EC 3.4.11.2): Acyl-[acyl-carrier- a nascent peptidoglycan a nascent peptidoglycan dependent synthetase II / Guanosine- : Leucyl/ degradation (EC 2.7.1.45): 2-dehydro-3- deoxygalactonokinase (EC 6-phosphogluconate 1.2.1.27): Methylmalonate- 2.3.1.9): 3-ketoacyl-CoA 2.3.1.9): 3-ketoacyl-CoA II (EC dehydrogenase G1RHH- putative: carboxyvinyl- dehydrogenase): Glutathione N-acetyltransferase C (EC 2.1.1.52): Che CDS dTDP-4-dehydro- D-glucosamine diphosphate succinocarbox Ribonucleotide reductase Nucleoside 5- : Inosine- dehydrogenase gluconate 6-phosphate (EC 1.14.19.1): Fatty acid synthase (EC 6.3.2.17): hydroxybenzoate a [TusE sulfur G1RHH-1897 demethylubiquinone- Membrane alanine 1.1.1.100): protein]--UDP-N- γ malic enzyme (EC 3.1.7.2): GTP Nucleoside Ribonucleotide phosphorylase (EC 3-phosphate Nucleoside triphosphate a 2-thiouridine 34 (EC 2.7.1.40) CDS CDS UDP-N-acetyl- with (L-alanyl- -D-glutamyl- with D,D cross-links (meso- α 6-phosphate kinase (EC 3',5'-bis(diphosphate) 3'- 4-hydroxy- phenylalanyl- deoxygluconate kinase (EC 2-dehydro-3-deoxy-D-gluconate dehydrogenase, semialdehyde desaturase (EC 1.14.19.1); thiolase (EC 2.3.1.16) @ thiolase (EC 2.3.1.16) @ 3.5.99.2) CDS (EC 1.2.1.3) CDS 1894 carboxyphosphonate NADPH-dependent 9 3-methyltransferase S-transferase G1RHH-1018 Ribosomal RNA met 6-deoxy- -D- pyrophosphokinase of class II (coenzyme triphosphatase RdgB uridine (EC 1.2.1.3) CDS dehydrogenase ethylene glycol UDP-glucose Dihydrofolate synthase + polyprenyltransferase 5-(hydroxymethyl) carrier protein]- 3-hexaprenyl- aminopeptidase acetylglucosamine meso-2,6-diaminopimeloyl- diaminopimelate containing) (EC 1.1.1.40) pyrophosphohydrolase diphosphate reductase Purine nucleoside tRNA--protein a [protein] 2-dehydro-3-deoxy-D-galactonate 6-phosphate decarboxylating D-galactose degradation II dehydrogenase AMP diphosphate H 3-nonaprenyl-4- 5-(2-hydroxyethyl) 3-(hydroxyphosphinoyl) in tRNA dGTP pyruvate methylglyoxal reductase domain protein N6'- small subunit Che D-glt α-D-muramoyl- 2.7.4.6) 3-methylbut- [+ 3 isozymes] [+ 3 isozymes] [+ 5 isozymes] 2 D-ribulose 5-phosphate glucopyranose Phosphoglucosamine (EC 2.7.6.5), kinase (EC of class II B12-dependent) (EC (dHAPTP, dITP, preferring an N-terminal [+ 5 isozymes] (EC 1.1.5.3): 5-keto-2-deoxy- 4-epimerase a ferricytochrome b palmitoleoyl-CoA (EC 6.3.2.12) @ -2-methyl-4(1H) L-cysteine 4-amino-5- N (EC [+ 3 isozymes] an N - a [protein]-L- O-acyltransferase D-alanine) tetrapeptide (EC 3.1.7.2): GTP SAICAR phosphorylase (EC N-terminal L- KDGP 2-dehydro-3- (EC 1.1.1.44): 6- + 5 hydroxybenzoate -4-methylthiazole NMN AMP [DNA] pyruvate acetylkanamycin-B L-alanine NADP- 2-enyl arginyl-[protein] H NADH hydrogencarbonate propanoyl-CoA acetyl-CoA 2-trans-nonenoyl-CoA acetyl-CoA decanoyl-CoA DMSP methylglyoxal methoxybenzoate [+ 7 isozymes] a (3R)-3- 1207 dTDP-4- mutase (EC 5.4.2.10): 2.7.4.6): (coenzyme B12- 1.17.4.1): Ribonucleotide XTP-specific) (EC nucleoside Aerobic glycerol- D-gluconate- 2-dehydro-3- (EC 5.1.3.2): a (6S)-5-formyltetrahydrofolate -pyrimidinone a peptide ala methylguanine glutamate-O (EC 2.3.1.129): pyrophosphokinase 2.4.2.1): Purine nucleoside diphosphate leucyl-L-arginine deoxygluconate kinase phosphogluconate D-galactopyranose hydroxydocosanoyl-[acp] Arabinose 5- L,D- dependent dehydrorhamnose Phosphoglucosamine reductase of class II 3.6.1.15): Nucleoside acetate 3-phosphate UDP-glucose methylmercury-S-glutatione in 16S rRNA -methyl-ester Acyl-[acyl-carrier- L,D- Adenylosuccinate Nucleoside dependent) phosphorylase (EC glycolaldehyde 6 phosphate 4-hydroxy-2-oxoglutarate (EC 2.7.1.45): 2-dehydro-3- deoxyphosphogalactonate dehydrogenase, UDP-N- phosphate a mature peptidoglycan malic enzyme mutase (EC 5.4.2.10) (EC 2.7.6.5), 5-triphosphatase uracil reductase 4-epimerase D-galactose 1- protein]--UDP-N- transpeptidase transpeptidase 3,5-epimerase GDP lyase (EC 4.3.2.2): diphosphate (EC 1.17.4.1): Ribonucleotide reductase adenine 4-hydroxy- dehydrogenase aldolase (EC aldolase (EC 4.1.3.16) deoxygluconate kinase (EC aldolase (EC 4.1.2.21) acetylmuramoylalanine- isomerase with D,D cross-links (meso- (EC 1.1.1.40) RdgB (dHAPTP, (EC 1.17.1.2) Leucyl/ Acetyl-coenzyme Aldehyde D-ribulose (EC 5.1.3.2) dehydrogenase YcbB: L,D- a nascent peptidoglycan YcbB: L,D- a mature peptidoglycan (EC 5.1.3.13): α-D-glucosamine Adenylosuccinate kinase (EC Ribonucleotide of class II (coenzyme 3-methylbut- 4.1.2.29): 5- @ 2-dehydro-3- : 2-dehydro-3- -D-glutamate ligase (EC 5.3.1.13) diaminopimelate containing) : NADP- CDP : 4-hydroxy- phenylalanyl- A synthetase DHAP dehydrogenase 5-phosphate CDS (EC 1.1.1.48): UDP-3-O-[(3R)-3- transpeptidase with (L-alanyl-γ-D- transpeptidase with (L-alanyl-γ-D-glutamyl- oxaloacetate G1RHH-1957 1-phosphate lyase (EC 2.7.4.6) reductase B12-dependent) (EC Adenine 2-enyl keto-2-deoxy- deoxyphosphogluconate KDGP deoxyphosphogalactonate (EC 6.3.2.9): UDP-N- : Arabinose dependent 3-methylbut- tRNA--protein (EC 6.2.1.1): D-galactose 1- YcbB CDS dTDP-4-dehydro- 4.3.2.2) CDS of class II 1.17.4.1): Ribonucleotide (EC 1.2.1.3) D-gluconate- [+ 2 isozymes] (2E,6Z,9Z,12Z,15Z,18Z,21Z) a single- adenosylcobinamide- guanosine 2251 a guanine 2445 3-[(4'- hydroxymyristoyl]-N- glutamyl-meso-2,6- YcbB CDS meso-2,6-diaminopimeloyl- Phosphoenolpyruvate Ribonucleotide reductase phosphoribosyltransferase diphosphate aldolase (EC 6-cis, 3-oxo-tridecenoyl-CoA 3-oxo-(7Z)-tetradecenoyl-CoA an N-formyl-L- an isoprenoid 3,4-dihydroxyphenylacetaldehyde 2+ α α acetylmuramoylalanine- 5-phosphate malic enzyme β N-acetylglucosamine- xanthine and 2-enyl transferase Acetyl-coenzyme : Aldehyde Ribulose- Ribose 5- dehydrogenase a (4Z)-hexadec-4-enoyl-[acp] a malonyl-[acp] acetoacetate 4-hydroxybenzoate (R)-glycerate protoporphyrin IX Mg -tomatine -ribazole 3',5'-diiodothyronine 2-oxoadipate (S)-mandelate a 3-oxodocosanoyl-[acp] methylsulfanyl) acetyl-α-D-glucosamine diaminopimelate) tripeptide D-alanine) tetrapeptide carboxykinase -L-rhamnose reductase of class II of class II (coenzyme (EC 2.4.2.7): Adenine reductase 6 phosphate 4.1.2.14): 4-hydroxy-2- 4-hydroxy-2-oxoglutarate D-glyceraldehyde 3-phosphate pyruvate diphosphate -tetracosaheptaenoyl-CoA stranded RNA GDP ATP H O in 23S rRNA in 23S rRNA diphosphate A synthetase (EC 1.1.1.48) methionylaminoacyl-tRNA 2 -D-glutamate isomerase (EC (EC 1.1.1.40) 1-phosphate AICAR Ribonucleotide xanthosine salvage (EC 2.3.2.6) dehydrogenase phosphate phosphate Acetoacetyl-CoA 3-ketoacyl-CoA thiolase 3-ketoacyl-CoA thiolase 4-hydroxybenzoate FIG146212: Enoyl-CoA Polyribonucleotide Aldehyde Glyoxylate reductase MG(2+) CHELATASE Beta-glucosidase Cobalamin Type I 2-oxoglutarate mandelate racemase/ 23S rRNA Ribosomal RNA butyl]malate UDP-3-O-[3- a nascent peptidoglycan a nascent peptidoglycan [ATP] (EC 4.1.1.49): dTDP-4- GTP dUDP B12-dependent) (EC phosphoribosyltransferase (EC (EC 1.17.1.2) oxoglutarate aldolase (EC aldolase (EC 4.1.3.16) 3-oxoacyl-[acyl-carrier- Peptide deformylase 3-oxoacyl-[acyl- pyruvate uridyltransferase reductase : Leucyl/ (EC 6.2.1.1) (EC 1.2.1.3) CDS 3-epimerase isomerase D-galactono-1,4-lactone synthetase [leucine] (EC (EC 2.3.1.16) @ Acetyl- (EC 2.3.1.16) @ Acetyl- hydratase (EC 4.2.1.17) nucleotidyltransferase dehydrogenase (EC FAMILY PROTEIN / (EC 3.2.1.21): synthase ATPase: Nitrate muconate lactonizing γ Phosphoenolpyruvate @ 2-dehydro-3- D-xylose protein] synthase, (EC 3.5.1.88): polyprenyltransferase (EC 1.1.1.79) / Glyoxylate iodothyronine dehydrogenase (guanosine-2'-O-) - carrier protein] small subunit UDP-N-acetyl- Arabinose 5- hydroxymyristoyl] N- with L,D cross links (meso- with (L-alanyl- -D-glutamyl- dehydrorhamnose IMP cyclohydrolase (EC 3.5.4.10) / Nucleoside diphosphate 1.17.4.1): Ribonucleotide : 4-hydroxy- phenylalanyl- ABC transporter, meso- (EC 2.7.7.23) / of class II Acetyl-coenzyme [+ 5 isozymes] 3-oxopropanoate D-glyceraldehyde 3-phosphate pyruvate deoxyphosphogluconate (EC 5.1.3.1) B (EC 6.2.1.16): Acetoacetyl-CoA CoA acetyltransferase (EC CoA acetyltransferase (EC (EC 2.5.1.39): 4- : FIG146212: Enoyl- (EC 2.7.7.8): 1.2.1.3): Aldehyde reductase (EC 1.1.1.26) / ComM-related protein: Beta-glucosidase (EC 2.7.8.26): deiodinase (EC E1 component enzyme family protein: methyltransferase reductase (EC methyltransferase α-D-muramoyl-L- phosphate acetylglucosamine diaminopimelate containing) meso-2,6-diaminopimeloyl- carboxykinase [ATP] reductase (EC reductase of class II xanthosine AMP 3-methylbut- IPP a [protein] KASII (EC 2.3.1.179): Peptide deformylase ATP-binding a mature peptidoglycan Glucosamine- Phosphoribosylaminoimidazolecarboxamide (coenzyme B12- kinase (EC 2.7.4.6): an N-terminal tRNA--protein Xylose : Ribulose- 5.3.1.6): 1,4-lactonase synthetase [leucine] (EC 2.3.1.9): 3-ketoacyl-CoA 2.3.1.9): 3-ketoacyl-CoA hydroxybenzoate CoA hydratase (EC Polyribonucleotide dehydrogenase Hydroxypyruvate reductase MG(2+) CHELATASE (EC 3.2.1.21) CDS G1RHH-2708 1.97.1.10): Type (EC 1.2.4.2): 2- mandelate racemase/ rlmB (EC 2.1.1.- C (EC 2.1.1.52): diaminopimelate isomerase deacetylase (EC glycine) tetrapeptide 1.1.1.133): 2-enyl Isopentenyl- N-terminal L- A synthetase aldolase (EC 3-oxoacyl-[acyl-carrier- (EC 3.5.1.88) CDS 1.1.1.100): alanyl-D-glutamate with (L-alanyl-γ-D- 1-phosphate N- formyltransferase (EC 2.1.2.3): dependent) Nucleoside diphosphate Ribonucleotide reductase glycolate isomerase phosphate Ribose 5- (EC 3.1.1.25): 1,4- thiolase (EC 2.3.1.16) @ thiolase (EC 2.3.1.16) @ nucleotidyltransferase (EC 1.2.1.3) CDS (EC 1.1.1.81): Glyoxylate FAMILY PROTEIN / β β I iodothyronine [+ 17 isozymes] oxoglutarate muconate lactonizing ): 23S rRNA Ribosomal RNA (EC 5.3.1.13) 3.5.1.108): UDP-3-O- G1RHH-1959 Purine nucleoside diphosphate L-lysyl-[protein] (EC 6.2.1.1): Methylmalonate- 4.1.2.14): 4-hydroxy-2- α-D-glucopyranose protein] synthase, polyprenyltransferase [+ 4 isozymes] -D-glucopyranose 2-tomatine G1RHH-1018 diphosphate leucyl-L-lysine [+ 2 isozymes] (3S,6Z,9Z,12Z,15Z,18Z,21Z)-3- + glutamyl-meso-2,6- acetyltransferase IMP cyclohydrolase (EC 3.5.4.10) / (EC 1.17.4.1): kinase (EC 2.7.4.6) of class II (coenzyme phosphorylase (EC pyrimidine nucleobases salvage II Acetyl-coenzyme oxoglutarate aldolase (EC (EC 5.3.1.5) 3-epimerase phosphate UDP-α-D-galactose lactonase (EC AMP diphosphate acetoacetyl-CoA [+ 3 isozymes] [+ 3 isozymes] a 4-hydroxy-3- a nucleoside a single- [+ 5 isozymes] reductase (EC 1.1.1.79) / GMP adenosylcobalamin deiodinase (EC H phosphate ADP dehydrogenase (guanosine-2'-O-) small subunit UDP-N- : Arabinose [3-hydroxymyristoyl] dTDP-β-L- delta- semialdehyde 1-phosphate acyl-carrier protein a (6Z)-3-oxooctadec-6-enoyl-[acp] Mg-protoporphyrin (R)-mandelate 2-O- [+ 3 isozymes] an N 2 - a mature peptidoglycan diaminopimelate) tripeptide (EC 2.3.1.157): N- Ribonucleotide B12-dependent) (EC : Xylose (EC isomerase 3.1.1.25) CDS formate a L-methionylaminoacyl-tRNA polyprenylbenzoate hydroxytetracosahexaenoyl-CoA diphosphate stranded RNA E1 component UDP-3-O-(3- phosphoenolpyruvate dUTP 2.4.2.1): Purine nucleoside A synthetase acetyl-CoA 4-cis-undecenoyl-CoA (5Z)-dodecenoyl-CoA acetyl-CoA 3,4-dihydroxyphenylacetate hydroxypyruvate iodide 3'-monoiodothyronine 2251 a (3R)-3- 2445 7-(methylsulfanyl) acetylmuramoylalanyl- 5-phosphate with L,D cross-links (meso- a mature peptidoglycan rhamnose FAICAR isomerase dehydrogenase methylguanosine methylguanine acetylglucosamine- reductase 1.17.4.1): Ribonucleotide phosphorylase (EC cytosine (EC 6.2.1.1) D-glyceraldehyde 3-phosphate pyruvate isomerase B (EC hydroxydocosanoyl-[acp] -2-oxoheptanoate D-glutamate--2,6- isomerase (EC hydroxymyristoyl) (EC 5.3.3.2): (EC 1.2.1.27): Ribulose- Phosphoglucomutase D-galactonate glutaryl-CoA NADH CO in 23S rRNA in 23S rRNA diaminopimelate containing) with (L-alanyl-γ-D-glutamyl- Enolase (EC 1-phosphate of class II Deoxyuridine reductase of class II 2 D-ala -α-D-glucosamine IMP cyclohydrolase (EC 3.5.4.10) / Purine nucleoside Cytosine deaminase DHAP (EC 5.3.1.5) (EC 5.4.2.2): diaminopimelate ligase aldehydo-D-arabinose meso-2,6-diaminopimeloyl- α 5'-triphosphate Isopentenyl- Methylmalonate- phosphate Ribose 5- UDP-3-O-[3- 4.2.1.11): N-acetyl- -D- Phosphoribosylaminoimidazolecarboxamide (EC 3.5.4.1): Cytosine acetyl-CoA CDS Phosphoglucomutase (EC 6.3.2.13): UDP-N- nucleotidohydrolase (EC dCDP phosphorylase (EC diphosphate Respiration semialdehyde 3-epimerase phosphate melibiose degradation 5-phosphate glycine) tetrapeptide Enolase (EC glucosamine deaminase (EC 3.5.4.1) CDS D-alanine- hydroxymyristoyl] formyltransferase (EC 2.1.2.3): 2.4.2.1): Purine nucleoside dehydrogenase (EC 5.4.2.2) CDS acetylmuramoylalanyl- 3.6.1.23): Deoxyuridine Nucleoside diphosphate delta- D-xylulose (EC 5.1.3.1) isomerase A -D-alanine glucosamine N- 4.2.1.11) CDS 1-phosphate IMP cyclohydrolase (EC 3.5.4.10) / Cytosine deaminase a [2-oxoglutarate- N-acetyl-β- a (7Z,10Z,13Z,16Z 34 1835 3-[(6'- dGDP phosphorylase (EC isomerase (EC 5.3.1.6) a 7,8-dihydro-8- + 3-amino-4- a cytidine 1,6-anhydro-N- a guanine D-glutamate--2, 5'-triphosphate kinase (EC 2.7.4.6): xanthine 2-oxoglutarate decarboxylation to succinyl-CoA : Ribulose- D-glucopyranose melibiose hydroxyatrazine linamarin ammonium NAD(P) H O (R)-glycerate cis-coumarinic acid-β-D-glucoside 3-demethylubiquinol-9 CTP a protein with ligase (EC acyltransferase N-acetylglucosamine- (EC 3.5.4.1): Cytosine DMAPP dehydrogenase an N-modified aminoacyl-[tRNA] stearoyl-CoA a ferrocytochrome b 2 a peptide with a leader sequence neuraminate ,19Z)-3-oxodocosa- glutathione β methylsulfanyl) 2-phospho-D-glycerate Xylulose phosphate : G1RHH- SAM a sulfurated [sulfur carrier] 5 a purine ribonucleoside xanthosine oxoguanine in DNA hydroxybenzaldehyde in tRNA acetyl- -muramate in 23S rRNA Nucleoside triphosphate Nucleoside diphosphate 6-phosphate Alpha-galactosidase 6 Beta- a disulfide bond hexyl]malate 6.3.2.4): D-arabinofuranose (EC 2.3.1.191) 1-phosphate deaminase (EC 3.5.4.1) CDS acetyl-CoA E2 protein] N - Peptidyl-tRNA hydrolase Guanine deaminase Formamidopyrimidine- Nitrite reductase Glyoxylate reductase Signal peptidase Beta-glucosidase 3-demethylubiquinone- Legionaminic acid N-acetyltransferase: 7,10,13,16,19-pentaenoyl-[acp]3-oxoacyl-[acyl- Glutaredoxin tRNA (cytidine(34) Anhydro-N- Ribosomal RNA UDP-N-acetyl- IMP Nucleoside kinase (EC 2.7.4.6) Xanthine-guanine a [2-oxoglutarate dehydrogenase kinase 3-epimerase 2697 (EC 3.2.1.22): Alpha- Lipoate Fatty acid desaturase Inosine-uridine preferring G1RHH- : UDP-3-O-[3- uridyltransferase pyrophosphohydrolase uracil octanoyl-L-lysine (EC 3.5.4.3); glucosidase (EC Inosine-uridine preferring DNA glycosylase [NAD(P)H]: Nitrite (EC 1.1.1.79) / Glyoxylate (EC 3.2.1.21): 9 3-methyltransferase cytidylyltransferase GCN5-related N- -2'-O)- acetylmuramic small subunit α-D-muramoyl- 5-phosphate 2,3-bisphosphoglycerate- diphosphate 6 (EC (EC (EC 3.1.1.29): Peptidyl- (EC 1.14.19.1); Delta- I (EC 3.4.21.89): carrier protein] 3 (Grx2): MazG (EC 3.6.1.8): phosphoribosyltransferase E2 protein] N -lipoyl-L-lysine galactosidase synthase: nucleoside hydrolase (EC 3.2.1.21): Beta- nucleoside hydrolase (EC reductase [NAD(P)H] reductase (EC 1.1.1.26) / Beta-glucosidase (EC 2.1.1.64): 3- acetyltransferase methyltransferase acid kinase (EC methyltransferase 2302 γ hydroxymyristoyl] independent (EC 2.7.7.23) / dCTP D-ribose 5- tRNA hydrolase 9 fatty acid desaturase Hydroxydechloroatrazine (EC 3.2.2.23): Signal peptidase I (EC 2.7.7.43): reductase (EC Glutaredoxin L-alanyl- -D- 2-Keto-3-deoxy- kinase (EC (EC 2.4.2.22): Uracil 2.7.1.17): (EC 3.2.1.22) CDS Lipoate 3.2.2.1): Inosine-uridine glucosidase (EC glucosamine Glucosamine- Nucleoside triphosphate 2-oxoglutarate ethylaminohydrolase 3.2.2.1): Inosine-uridine Formamidopyrimidine- small subunit Nitrite Hydroxypyruvate reductase (EC 3.2.1.21) CDS demethylubiquinone- Legionaminic acid CDS 1.1.1.100): (EC 2.1.1.207): tRNA 2.7.1.-): Anhydro- C (EC 2.1.1.52): glutamyl-meso-2,6- D-manno- phosphoglycerate 2.7.4.6): Xanthine-guanine phosphoribosyltransferase Xylulose D-xylulose phosphate D-galactopyranose D-glucopyranose a [2-oxoglutarate (EC 3.1.1.29) CDS (EC 1.14.19.1): Fatty acid preferring nucleoside (EC 3.4.21.89) CDS a protein with 3 (Grx2) CDS D-alanyl-D-alanine synthase CDS (EC 3.5.99.3): Guanine 3.2.1.21) CDS preferring nucleoside DNA glycosylase (EC reductase [NAD(P) (EC 1.1.1.81): Glyoxylate 9 3-methyltransferase cytidylyltransferase [+ 6 isozymes] (cytidine(34)-2'-O) N-acetylmuramic Ribosomal RNA diaminopimelate UDP-2-N,3-O-bis[(3R)- mutase (EC 1-phosphate N- Nucleoside dUMP (EC 2.4.2.9): Uracil dehydrogenase kinase 5-phosphate an unsulfurated dehydrogenase an N-modified amino acid an uncharged tRNA desaturase (EC 1.14.19.1); a leader sequence a peptide D-glucopyranose coumarinate G1RHH-1018 reduced L- GSSG octulosonate- Aromatic Compound Biosynthesis Inosine-5'- phosphoribosyltransferase Entner-Doudoroff pathway I 5'-deoxyadenosine met a purine base D-ribofuranose 2-hydroxy-2- xanthine D-ribofuranose an apurinic site 7,8-dihydro- 3-acetylamino-4- acid kinase (EC 3-hydroxytetradecanoyl]- acetyltransferase E1 component 6 deaminase (EC 3.5.4.3); D-glucopyranose H] large subunit reductase (EC 1.1.1.79) / ubiquinol-9 (EC -methyltransferase 2 small subunit 8-phosphate 5.4.2.1): 2,3- diphosphate Thymidylate synthase thyX phosphoribosyltransferase (EC Inorganic Nutrient Metabolism (EC [sulfur carrier] E2 protein] N a ferricytochrome b oleoyl-CoA CMP-N-acetyl- a (3R,7Z,10Z,13[+Z,16 3 isozymes]Z cysteine residues a 2'-O- an N - α monophosphate 5 methylpropanenitrile within DNA 8-oxoguanine hydroxybenzaldehyde N-acetyl-D-muramate -D-glucosamine bisphosphoglycerate- (EC 2.3.1.157): N- (EC 1.2.4.2): 2- ethylamine N-isopropylammelide nitrite hydroxypyruvate 34 1835 9-(methylsulfanyl) UDP-N- synthase (EC dehydrogenase (EC kinase (EC (EC 2.1.1.-): G1RHH-2657 2.7.1.17) -lipoyl-L-lysine β-neuraminate ,19Z)-3-hydroxydocosa- methylcytidine methylguanine enterobactin biosynthesis acetylglucosamine- XMP UMP oxoglutarate Transketolase D-glucopyranose 6-phosphate 6-phosphate -2-oxononanoate acetylmuramoylalanyl- 2.5.1.55): 2- 4-hydroxyphenylpyruvate independent 1.1.1.205): Inosine- 2.7.4.6) CDS 7,10,13,16,19-pentaenoyl-[acp] in tRNA in 23S rRNA 1-phosphate dTMP dehydrogenase superpathway of sulfate assimilation and cysteine biosynthesis selenate reduction (EC 2.2.1.1): D-glutamyl-2,6- Keto-3-deoxy- biosynthesis 5'-monophosphate sulfoacetaldehyde degradation I hypotaurine degradation 3-phospho-D-glycerate Dihydrolipoamide taurine degradation I D-xylulose Glucose-6-phosphate diaminopimelate--D- chorismate UDP-N-acetyl- dGTP Thymidylate kinase (EC E1 component Transketolase D-manno- dehydrogenase (EC dehydrogenase 5-phosphate 1-dehydrogenase (EC lipid X α α-D-glucosamine 2.7.4.9): G1RHH-1842 sulfate (EC 2.2.1.1) CDS alanyl-D-alanine ligase octulosonate- tyr Phosphoglycerate UDP- -D-glucose [+ 2 isozymes] selenate sulfoacetaldehyde hypotaurine Isochorismate Inosine-5'- a [2-oxoglutarate (EC 1.8.1.4):a [2-oxoglutarate dehydrogenase taurine glyphosate 1.1.1.49): Glucose- a [pyruvate di-trans,octa-cis a ring-opened 7- (2E,6Z,9Z,12Z,15Z,18Z) a dimer of adjacent γ an N-acyl-D- 3-[(5'- (EC 6.3.2.10): UDP-N- 8-phos biosynthesis I D-sedoheptulose D-glyceraldehyde UDP-α-D- -glutamyl-p- + O-ureido-L- 3-[(7'-methylsulfanyl) kinase (EC 2.7.2.3) dTDP Dihydrolipoamide 6 Sulfate adenylyltransferase Sulfate Taurine--pyruvate 6-phosphate 1- pyruvate ν glycyl-glycine (R)-glycerate FMN NAD(P)H H 3-demethylubiquinol-6 PLP uroporphyrinogen-I a cytosine in DNA methylsulfanyl) Lipid-A- synthase (EC Biosynthetic monophosphate dehydrogenase E2 protein] E2 protein] N -S- 3-phospho-D-glycerate Taurine--pyruvate degradation II 7-phosphate 3-phosphate dehydrogenase -undecaprenyl methylguanine in DNA -tetracosahexaenoyl-CoA thymidine and 2'- h nitroanilide L-saccharopine a PII protein UTP 2-oxoglutarate D-ala mannosamine asp heptyl]malate acetylmuramoylalanyl- 6 adenylyltransferase SAM a sulfurated [sulfur carrier] galactose inosine homoserine disaccharide Aromatic : Phosphoglycerate D-glucopyranose dehydrogenase (EC N -dihydrolipoyl-L-lysine dehydrogenasesuccinyldihydrolipoyl-L-lysine (EC (EC 2.7.7.4) / aminotransferase dehydrogenase (EC E2 protein] N 6 - phosphate Pyruvate,phosphate Formamidopyrimidine- FIG146212: Enoyl-CoA deoxycytidine in DNA Gamma- NADPH-dependent 3-demethylubiquinone- Uroporphyrinogen N-acetylmannosamine pentyl]malate D-glutamyl-2,6- 5.4.4.2) of Nucleoside diphosphate Sulfoacetaldehyde aminotransferase Undecaprenyl-phosphate Deoxyribodipyrimidine Saccharopine Glyoxylate reductase [Protein-PII] Pyridoxal-5'-phosphate D-alanine 3-isopropylmalate DNA-cytosine KDO-8P kinase (EC 6-phosphate D-3-phosphoglycerate (EC 2.7.7.4) / (EC 2.6.1.77): Lipoate DNA glycosylase Inosine-uridine preferring kinase (EC 2.7.1.60): Argininosuccinate synthase (EC siderophore amino acid 1.1.1.205): Inosine- kinase (EC 2.7.4.6): 2-oxoglutarate Adenylylsulfate kinase acetyltransferase glyphosate octanoyl-L-lysine dikinase (EC 2.7.9.1) hydratase (EC 4.2.1.17) glutamyltranspeptidase dehydrogenase [NAD+, (EC 1.1.1.79) / Glyoxylate uridylyltransferase (EC FMN reductase: 9 3-methyltransferase III decarboxylase dehydrogenase methyltransferase Phosphoglucomutase Adenylylsulfate kinase (EC 2.6.1.77): Transaldolase 6-phospho D-glucono-1,5-lactone galactosephosphotransferase photolyase (EC 4.1.99.3) phosphatase (EC 3.1.3.74) aminotransferase synthase UDP-N- 2.4.1.182): Lipid- biosynthesis: aminotransferase 2.7.2.3) CDS 5'-monophosphate (EC 2.7.1.25): Sulfate dehydrogenase Taurine--pyruvate Glycine/D- synthase: : Pyruvate,phosphate (EC 3.2.2.23): nucleoside hydrolase (EC : FIG146212: Enoyl- (EC 2.3.2.2): Gamma- reductase (EC 1.1.1.26) / NADPH-dependent (EC 2.1.1.64): 3- (EC 4.1.1.37): N-acetylmannosamine (EC 1.1.1.85): 3- (EC 2.1.1.37): (EC 5.4.2.2): PRPP biosynthesis UMP biosynthesis II Nucleoside diphosphate dehydrogenase (EC 2.3.3.15): Taurine--pyruvate (EC 2.2.1.2): (EC 2.7.8.6): : Deoxyribodipyrimidine L-lysine-forming] (EC 2.7.7.59): [Protein-PII] , Alphaproteobacterial type: (EC 2.6.1.21) (EC 6.3.4.5): acetylmuramoylalanyl- A-disaccharide beta (EC 2.6.1.57) adenylyltransferase (EC 1.1.1.95): D-3- (EC 2.7.1.25): Sulfate aminotransferase Lipoate Formamidopyrimidine- 3.2.2.1): Inosine-uridine CoA hydratase (EC glutamyltranspeptidase FMN reductase CDS Uroporphyrinogen kinase (EC 2.7.1.60) G1RHH-1020 Phosphoglucomutase dehydrogenase (EC kinase (EC 2.7.4.6) E1 component Sulfoacetaldehyde aminotransferase amino acid 6-phosphogluconolactonase Undecaprenyl-phosphate dikinase (EC 2.7.9.1) 1.5.1.7): Saccharopine Hydroxypyruvate reductase uridylyltransferase (EC demethylubiquinone- Pyridoxal-5'-phosphate : D-alanine an N-acyl-α-D- isopropylmalate DNA-cytosine 13-DPG phosphoglycerate adenylyltransferase (EC Transaldolase synthase CDS a [pyruvate α preferring nucleoside photolyase (EC Argininosuccinate D-glutamyl-2,6- synthase (EC : Biosynthetic (EC 1.2.4.2): 2- NADH repair (EC 2.7.7.4) / oxidase: -D-galactosyl- DNA glycosylase (EC [+ 4 isozymes] adjacent thymidine-2'- (EC 2.3.2.2) (EC 1.1.1.81): Glyoxylate NAD(P) + FMNH 9 3-methyltransferase III decarboxylase (EC dehydrogenase methyltransferase (EC 5.4.2.2) CDS D-ribose 5- dTTP acetyltransferase (EC (EC (EC 2.2.1.2) CDS (EC 3.1.1.31), an unsulfurated dehydrogenase UMP phosphoenol 2,6-diamino-4- dehydrogenase [NAD+, a uridylylated PII protein 2 phosphatase (EC aminotransferase mannosamine synthase diaminopimelate-- isochorismate Aromatic amino acid α-D-glucopyranose dehydrogenase (EC (EC 2.7.7.4) / 2-sulfinoacetaldehyde 5'-deoxyadenosine met diphosphoundecaprenol diphosphate AMP H + hypoxanthine D-ribofuranose (3S,6Z,9Z,12Z,15Z,18Z)-3- γ-L-glutamyl- hydrogencarbonate gln oxoglutarate adenosine 5'- Glycine/D- 6 an apurinic site deoxycytidine in DNA reductase (EC 1.1.1.79) / (EC (EC α-Kdo lipid A disaccharide (E. coli) phosphate Dihydrolipoamide APS ala sulfoacetaldehyde eukaryotic type: 6- [sulfur carrier] E2 protein] N pyruvate hydroxy-5-(N-methyl) 4-nitroaniline lys 2-oxoglutarate ubiquinol-6 pyridoxal coproporphyrinogen I (EC 2.6.1.21) 6-phosphate (EC 6.3.4.5) D-alanyl-D-alanine 3-(4- NAD-dependent 1-phosphate Ribose-phosphate [+ 3 isozymes] within DNA hydroxytetracosapentaenoyl-CoA glycylglycine 10-(methylsulfanyl) a 5-methylcytosine 8-(methylsulfanyl) [+ 2 isozymes] dehydrogenase NADH phosphoselenate amino acid D-erythrose phosphogluconolactonase formamidopyrimidine hydroxypyruvate Isochorismatase glyceraldehyde- succinyltransferase F6P -lipoyl-L-lysine pyruvate D-glt canavaninosuccinate -2-oxodecanoate in DNA ligase (EC 6.3.2.10) 3-deoxy-manno- hydroxyphenyl) UTP--glucose- pyrophosphokinase Carbamoyl-phosphate E1 component acetyl phosphate sulfite oxidase CDS 4-phosphate -2-oxooctanoate Tetraacyldisaccharide (EC 3.3.2.1) of XMP component (E2) Sulfate adenylyltransferase 3-phosphooxypyruvate (aminomethyl) (EC 3.1.1.31), : G1RHH-2304 octulosonate pyruvate 3-phosphate 1-phosphate (EC 2.7.6.1): glyoxylate 4'-kinase (EC 2.7.1.130) siderophore synthase large of 2-oxoglutarate (EC 2.7.7.4) / phosphonate dehydrogenase Ribose-phosphate Phosphate Transketolase D-gluconate 6-phosphate cytidylyltransferase : Tetraacyldisaccharide biosynthesis: uridylyltransferase GMP synthase chain (EC 6.3.5.5): dehydrogenase: Adenylylsulfate kinase Phosphoserine assimilatory sulfate reduction III acetaldehyde UDP-N-acetyl- Triosephosphate (EC 1.2.1.12): pyrophosphokinase superpathway of pyrimidine deoxyribonucleoside salvage acetyltransferase (EC (EC 2.2.1.1): (EC 2.7.7.38): 4'-kinase (EC G1RHH-1016 (EC 2.7.7.9): UTP-- [glutamine- Carbamoyl-phosphate 2-oxoglutarate (EC 2.7.1.25): Sulfate aminotransferase (EC selenite α-D-muramoyl- isomerase NAD-dependent (EC Transketolase Phosphogluconate 5-amino-4- 2-amino-6-[1-hydroxyethyl]- (9Z,12Z,15Z,18Z)-3- a 5-carboxymethylaminomethyluridine 34 a dimer of adjacent RNase E mRNA adenosine 3-[(3'- 3-deoxy-manno- 4'-phosphopantetheinyl glucose-1-phosphate hydrolyzing] (EC synthase large chain adenylyltransferase 2.3.1.8): Phosphate Aldehyde adenosylcobinamide- 4-methylphenyl carboxynorspermidine arbutin + a carboxypeptidase β-D-fructofuranose a PepB aminopeptidase 2+ dehydrogenase (R)-NADHX 2.6.1.52): Phosphoserine PRPP Leu 2'-deoxycytidine and hν pentanoyl-CoA acetate processing hydrogencarbonate H 3-demethylubiquinol-7 cobalt-precorrin-2 2',3'-cyclic 2-phosphoglycolate precorrin-2 Co methylsulfanyl) L-alanyl-γ-D- octulosonate lipid IV Isochorismatase (EC 5.3.1.1): glyceraldehyde- PRPP 2'-deoxycytidine sulfate acetyltransferase (EC 2.2.1.1) CDS dehydratase (EC 4.2.1.12) quinoxaline-2-carboxyl adenylate aryl-carrier protein imidazolecarboxyamide 7-methyl-7,8-dihydropterin GDP ribotide phosphate oxotetracosatetraenoyl-CoA in tRNA A [EntB aryl- transferase entD 6.3.5.2): GMP (EC 2.7.7.4) / dehydrogenase Beta-glucosidase Taq substrate Fructokinase (EC substrate Triosephosphate 3-phosphate UDP-α-D-glucose Carbamoyl-phosphate E1 component NAD(P)HX aminotransferase (EC Adenine 2-amino-4-hydroxy-6- Acetoacetyl-CoA tRNA (cytidine(34)-2'- thymidine in DNA Carboxynorspermidine Acetyl-CoA:acetoacetyl- substrate Carbonic anhydrase 3-demethylubiquinone- Cobalt-precorrin-2 monophosphate Phosphoglycolate Sirohydrochlorin propyl]malate glutamyl-meso-2,6- di-trans,octa-cis (EC 3.3.2.1) of carrier protein] [EntF L-seryl- Sulfate adenylyltransferase (EC 2.3.1.8) thiosulfate D-glyceraldehyde : Phosphogluconate Acyl carrier protein: Cobalamin Deoxyribodipyrimidine Ribonuclease E Thermostable 2',3'-cyclic-nucleotide Peptidase B (EC 2.7.8.-); synthase [glutamine- synthase small Dihydrolipoamide epimerase / Phosphoserine (EC 1.2.1.3) phosphoribosyltransferase hydroxymethyldihydropteridine reductase (EC 1.1.1.36) O)-methyltransferase dehydrogenase, CoA transferase, alpha (EC 3.2.1.21): (EC 4.2.1.1): 9 3-methyltransferase C20-methyltransferase 2.7.1.4): Fructokinase diaminopimeloyl- -undecaprenyl CMP-Kdo siderophore isomerase Cytidine deaminase PAPS (EC 2.7.7.4) / disproportionation dehydratase (EC 4.2.1.12) Acyl carrier protein CDS synthase photolyase (EC 4.1.99.3) (EC 3.1.26.12) carboxypeptidase 2'-phosphodiesterase (EC 3.4.11.23) phosphatase cobaltochelatase carrier protein]Holo-[acyl-carrier [+ 3 isozymes] hydrolyzing] (EC succinyltransferase NAD(P)HX Phosphate : Aldehyde 3-phosphate Beta-glucosidase (EC 2.7.1.4) CDS D-alanyl-D-alanine biosynthesis: Holo-[acyl- (EC 5.3.1.1) chain (EC 6.3.5.5): (EC 3.5.4.5): aminotransferase (EC Adenylylsulfate kinase (EC 2.4.2.7): Adenine pyrophosphokinase (EC (EC 2.7.8.26): of ethylmalonyl-CoA (EC 2.1.1.207): tRNA putative (EC 1.1.1.- subunit (EC 2.8.3.8): Carbonic anhydrase (EC 2.1.1.64): 3- (EC 2.1.1.130): Cobalt- (EC 3.1.3.18): (EC 4.99.1.3): phosphate D-glyceraldehyde selenodiglutathione acetyltransferase (EC urea cycle IV (rhodanese) Acyl carrier protein: : Deoxyribodipyrimidine : Ribonuclease 1 (EC 3.4.17.19) (EC 3.1.4.16): 2',3'- : Peptidase B protein] synthase, DHAP Carbamoyl-phosphate Cytidine deaminase dehydratase: 2.6.1.52): G1RHH-2557 dehydrogenase NAD-dependent KDGP phosphoribosyltransferase (EC 2.7.6.3): 2-amino-4-hydroxy-6- pathway: Acetoacetyl-CoA (cytidine(34)-2'-O) ): G1RHH-2086 Acetyl-CoA:acetoacetyl- (EC 3.2.1.21) CDS (EC 4.2.1.1) CDS demethylubiquinone- precorrin-2 C20- Fructokinase (EC Phosphoglycolate Sirohydrochlorin Lipid IVA 3- G1RHH-1019 carrier dCMP [+ 2 isozymes] Phosphoadenylyl-sulfate (EC 2.7.1.25): Sulfate Acyl carrier protein CDS [1-(2-amino-7-methyl-4-oxo- G1RHH-2708 photolyase (EC E (EC : G1RHH-1913 cyclic-nucleotide (EC 3.4.11.23) alternative (EC 3-phosphate GMP synthase small chain NAD(P)HX 2.3.1.8): Phosphate (EC 1.2.1.3) CDS thiosulfate 4-methylphenyl-Co deoxy-D-manno- (2S,3S)-2,3- protein] (EC 3.5.4.5) CDS reductase [thioredoxin] adenylyltransferase glyceraldehyde- AICAR reductase (EC 1.1.1.36) of -methyltransferase adjacent 2'-deoxycytidine- propane- L-aspartate 4- CoA transferase, hydroquinone D-glucopyranose H O CO 9 3-methyltransferase a proteinogenic methyltransferase 2.7.1.4): Fructokinase phosphatase cobaltochelatase Phospho-N- a quinoxaline-2-carboxyl- 7,8-dihydro-3H-pteridin- 3.1.26.12)RNase CDS E 2 2 a peptide 3'-AMP CDS 2.7.8.7): G1RHH-1017 Cytidylate kinase epimerase / 3-phospho-L-serine acetyltransferase [+ 5 isozymes] Rhodanese 3-phosphate AMP GMP β-adenosylcobamide (3R,9Z,12Z,15Z,18Z)-3- a 5-carboxymethylaminomethyl- thymidine in DNA 1,3-diamine semialdehyde (EC 2.7.1.4) CDS acetylmuramoyl- octulosonic acid dihydroxy-2,3- synthase (EC 1.8.4.8) / Adenylyl- (EC 2.7.7.4) / arg ammonium 6-yl)]ethyl diphosphate acetyl-CoA pentanoate ubiquinol-7 amino acid cobalt-precorrin-3 a proteinogenic (EC 3.1.3.18) (EC asp asp (EC 2.7.4.25): NAD(P)HX (EC 2.3.1.8) [aryl-carrier protein] hydroxytetracosatetraenoyl-CoA 2'-O-methyluridine 34 in tRNA Leu an mRNA fragment processing a peptide dihydrobenzoate (EC ATP-binding protein carbamoyl phosphate 2'-deoxyuridine sulfate reductase APS domain protein: dehydrogenase 4-hydroxy-2-oxoglutarate 5'-phosphate amino acid 6-(methylsulfanyl) pentapeptide- transferase Holo-[acyl- Cytidylate kinase acetate product mRNA F6P glycolate cobalt-precorrin-2 2.7.8.7): PhnN; Guanylate dehydratase Phosphoserine G1RHH-2291 (EC 1.2.1.12): aldolase (EC 4.1.3.16) -2-oxohexanoate transferase (EC 2.4.99.12) 2,3-dihydro-2,3- carrier (S)-NADHX [thioredoxin] (EC 1.8.4.10) glutathioselenol acetyl-CoA Arginase/agmatinase/ Carbamoyl- kinase (EC 2.7.4.8) Adenylosuccinate (EC 2.7.4.25) CDS phosphatase (EC Phosphoadenylyl-sulfate [+ 2 isozymes] NAD-dependent @ 2-dehydro-3- (EC 2.7.8.13) [often with (EC dihydroxybenzoate Holo-[acyl- protein] Thymidine kinase : Phosphoadenylyl- formimionoglutamate phosphate synthase Fructose- : ATP-binding synthetase Aspartate 3.1.3.3): Phosphoserine reductase [thioredoxin] sulfite thiocyanate glyceraldehyde- deoxyphosphogluconate : Phospho-N- 2.4.99.13) also]: dehydrogenase: carrier synthase GDP-L-fucose (EC 2.7.1.21): dCDP sulfate reductase hydrolase: Arginase/ large chain (EC bisphosphate protein PhnN; (EC 6.3.4.4): carbamoyltransferase phosphatase (EC 3.1.3.3) (EC 1.8.4.8) / Adenylyl- 3-phosphate aldolase (EC acetylmuramoyl- Lipid IVA 3- G1RHH-1018 protein] (EC biosynthesis I (from Thymidine kinase thymidine agmatinase/ 6.3.5.5): Carbamoyl- aldolase class (EC 2.1.3.2): Aspartate Nucleoside diphosphate Argininosuccinate methylthiopropanoate a [glycine-cleavage 5,10-methylene- 3-methyl-2- a dimer of non-adjacent (9Z,12Z,15Z,18Z,21Z)-3- a dimer of adjacent 3-demethylubiquinol- a 3- guanosine a nucleoside a uracil 1939 synthase Guanylate kinase G1RHH-2690 (EC 2.7.1.21) CDS sulfite sulfate reductase [+ 3 isozymes] 4.1.2.14): 4-hydroxy-2- glutathione glycyl-glycine a β-D glucoside carboxyspermidine butanoyl-CoA acetate canavaninosuccinate cholate a nucleoside a [protein] Ser/Thr roseoflavin pentapeptide- deoxy-D-manno- 2,3- 2.7.8.7): GDP-D-mannose) carbamoyltransferase (EC kinase (EC 2.7.4.6): lyase (EC 4.3.2.1): formimionoglutamate phosphate degradation I (cleavage) SAM complex H protein] a sulfurated [sulfur carrier] thymidine and 2'- hν an acyl-[acyl-carrier protein] pyrimidine hν 2',3'-cyclic cyclic 3',5'- a protein (EC I (EC 4.1.2.13) Thymidine kinase ser hydrogen selenide [thioredoxin] (EC 1.8.4.10) oxoglutarate aldolase (EC tetrahydromethanopterin oxobutanoate oxotetracosapentaenoyl-CoA 10 triphosphate demethyubiquinol in 23S rRNA octulosonic acid Holo-[acyl- α Guanylate kinase NADH synthase large chain 6 Beta-glucosidase dihydroxybenzoate : Fructose- GDP-α-D-mannose UDP- -D-galactose Nucleoside diphosphate Sulfite reductase Argininosuccinate Arginase (EC 3.5.3.1) N -octanoyl-L-lysine 3-methyl-2-oxobutanoate deoxycytidine in DNA Acetoacetyl-CoA Gamma- nucleosides in DNA Carboxynorspermidine Acetyl-CoA:acetoacetyl- Argininosuccinate 7-alpha-hydroxysteroid 3-demethylubiquinone- Nucleoside triphosphate 3-demethylubiquinone- serine/threonine monophosphate monophosphate 23S rRNA (Uracil-5-) Rib adenylo-succinate dUMP (EC 2.7.1.21): : Phosphoadenylyl- 3-(methylsulfanyl) 13-DPG Lipoate Deoxyribodipyrimidine Phosphate:acyl-ACP Deoxyribodipyrimidine 2',3'-cyclic-nucleotide 3',5'-cyclic-nucleotide ATP-dependent Clp undecaprenyldiphospho- [+ 2 isozymes] carrier GDP-mannose biosynthesis (EC 2.7.4.8): : G1RHH-1884 hydroxymethyltransferase reductase (EC 1.1.1.36) glutamyltranspeptidase (EC 3.2.1.21): dehydrogenase, CoA transferase, alpha lyase (EC 4.3.2.1): dehydrogenase: 7- 9 3-methyltransferase 9 3-methyltransferase protein kinase: -methyltransferase (EC 2,3- 4'-phosphopantetheinyl bisphosphate Thymidine kinase kinase (EC 2.7.4.6) [NADPH] hemoprotein Serine acetyltransferase sulfate reductase lyase (EC Carbamoyl- propanoate synthase: photolyase (EC 4.1.99.3) acyltransferase PlsX: photolyase (EC 4.1.99.3) pyrophosphohydrolase 2'-phosphodiesterase phosphodiesterase protease proteolytic N-acetylmuramoyl-L- protein] Guanylate kinase Adenylosuccinate N-carbamoyl-L-aspartate D-glyceraldehyde 3-phosphate pyruvate (EC 2.1.2.11): 3- of ethylmalonyl-CoA (EC 2.3.2.2): Gamma- Beta-glucosidase putative (EC 1.1.1.- subunit (EC 2.8.3.8): Argininosuccinate (EC 2.1.1.64): 3- serine/threonine RumA (EC 2.1.1.-): ade dihydroxybenzoate- transferase entD aldolase 4,6-dehydratase (EC 2.7.1.21) CDS beta-component (EC (EC 2.3.1.30): Serine 4.3.2.1) CDS phosphate synthase Lipoate : Deoxyribodipyrimidine Phosphate:acyl-ACP : Deoxyribodipyrimidine alpha-hydroxysteroid (EC 2.1.1.64): 3- MazG (EC 3.6.1.8): (EC 3.1.4.16): 2',3'- (EC 3.1.4.17): 3',5'- subunit (EC 3.4.21.92) alanyl-γ-D-glutamyl-meso α-Kdo-(2->6)-lipid IV synthase UDP-α-D-glucose (EC 2.7.4.8) CDS dCTP Phosphoglycerate (EC 3.2.1.21) CDS A AMP ligase (EC 2.7.8.-); class I (EC (EC 4.2.1.47): lyase (EC 4.3.2.2): small chain (EC methyl-2-oxobutanoate pathway: Acetoacetyl-CoA glutamyltranspeptidase ): G1RHH-2086 Acetyl-CoA:acetoacetyl- lyase (EC 4.3.2.1) CDS dehydrogenase CDS demethylubiquinone- demethylubiquinone- protein kinase CDS 23S rRNA (Uracil-5- (EC 1.8.1.2): Sulfite reductase acetyltransferase sulfite L-arginino-succinate L-ornithine kinase (EC 2.7.2.3) synthase CDS a [glycine-cleavage photolyase (EC acyltransferase PlsX photolyase (EC α α Nucleoside triphosphate cyclic-nucleotide cyclic-nucleotide : ATP-dependent Clp -2,6-diaminopimeloyl- (EC GDP-mannose UDP-glucose Adenylosuccinate Dihydroorotase (EC 6.3.5.5): Carbamoyl- 3-(methylsulfanyl) NAD-dependent an unsulfurated a 2'-deoxycytidine reductase (EC 1.1.1.36) of (EC 2.3.2.2) a non glucosylated two adjacent pyrimidine L-aspartate 4- CoA transferase, 3 ,12 -dihydroxy-7- 9 3-methyltransferase a nucleoside 5'- 9 3-methyltransferase [+ 5 isozymes] ) -methyltransferase Rib (EC 2.7.7.58) Holo-[acyl-carrier [NADPH] hemoprotein (EC 2.3.1.30) : Phosphoglycerate met THMPT 2-dehydropantoate a thymidine in DNA acyl-carrier protein an acyl phosphate D-glucopyranose putrescine fumarate L-canavanine 3'-GMP phosphodiesterase a 5- protease proteolytic D-alanyl-D-alanine KDO transferase: ser GDP 3.5.2.3): Dihydroorotase propanoyl-CoA glyceraldehyde-3- 5'-deoxyadenosine complex H protein] (3R,9Z,12Z,15Z,18Z,21Z)-3- γ-L-glutamyl- D-glucose acceptor semialdehyde oxo-5β-cholan-24-oate monophosphate (EC of siderophore protein] synthase, 4,6-dehydratase 4-epimerase lyase (EC Sulfite reductase phosphate [sulfur carrier] 6 in DNA L-cysteinylglycine nucleosides in DNA acetyl-CoA butanoate ubiquinol-10 UQH a [protein] (L-serine/L- a nucleoside 5'- 1939 Lipid IVA 3- Argininosuccinate kinase (EC N -lipoyl-L-lysine 2 methyluracil a peptide UDP-N- biosynthesis: alternative (EC (EC 4.2.1.47) (EC 5.1.3.2): 4.3.2.2) CDS (EC 3.5.2.3) CDS hydrogen sulfide O-acetyl-L-serine [NADPH] hemoprotein synthase small chain 3-methylmercaptopropionyl- phosphate dehydrogenase hydroxytetracosapentaenoyl-CoA glycylglycine threonine) phosphate monophosphate roseoflavin deoxy-D-manno- GDP-4-dehydro- 2.7.2.3) CDS in 23S rRNA acetylglucosamine- UDP-glucose 4- synthase (EC 6.3.4.5) CoA dehydrogenase (EC 1.2.1.12): NAD- 5'-phosphate G1RHH-1015 2.7.8.7): G1RHH-1017 α Dihydroorotase (EC superpathway of pyrimidine beta-component (EC octulosonic acid -D-rhamnose : Argininosuccinate 3-phospho- dependent glyceraldehyde- D-galactosamine and N-acetyl- -N-acetylmuramyl- (2,3- β-D-fructose 1,6- epimerase (EC 3.5.2.3): Dihydroorotase nucleobases salvage 1.8.1.2): Sulfite reductase carbamoyl phosphate (DmdC): 3- α-Kdo-(2->4)-α- a holo-[EntB aryl- GDP-L-fucose AMP dTMP Cysteine synthase: synthase (EC 6.3.4.5) Ornithine D-glycerate 3-phosphate D-galactosamine degradation (pentapeptide) dihydroxybenzoyl) a holo-[EntF bisphosphate 5.1.3.2) CDS (EC 3.5.2.3) CDS [NADPH] hemoprotein methylmercaptopropionyl- Kdo-(2->6)-lipid IV carrier protein] synthetase uracil Cysteine synthase CDS carbamoyltransferase pyrophosphoryl- A adenylate L-seryl-carrier (L-seryl)adenylate [+ 2 isozymes] Thymidylate kinase (EC CoA 2,3-bisphosphoglycerate- [+ 3 isozymes] Fructose-1,6- Adenylate kinase Cysteine synthase (EC 2.1.3.3): Ornithine a dimer of non-adjacent 37 a dimer of non- a dimer of non- a ribonucleoside 3-amino-4- UDP-N-acetyl- undecaprenol N- (EC 1.1.1.271): UDP-α-D-galactose (S)-dihydroorotate Uracil hydrogen sulfide N-acetyl-D-galactosamine 6-phosphate an adenosine β + 3-hydroxy- RNase E degradation protein] Ribonucleotide 2.7.4.9): G1RHH-1842 3-(methylsulfanyl) independent a ribonucleic acid ν (4S)-4-hydroxy-2-oxoheptanedioate lotaustralin ν p-nitrophenyl- -D-galactoside L-phosphinothricin FMNH NADP chenodeoxycholate H O an arylamine 3-ethylmalate α 2'-deoxycytidine and h DL-allothreonine DMAPP adjacent pyrimidine h adjacent 2'- 2 2 sarcosine 2',3'-cyclic -D-glucosamine acetylglucosamine bisphosphatase, GDP-L-fucose (EC 2.7.4.3): phosphoribosyltransferase (EC 2.5.1.47): Cysteine carbamoyltransferase phosphoglycerate 13-DPG N-acetylglucosamine-6- dGTP in tRNA hν isobutanoyl-CoA substrate mRNA hydroxybenzoate reductase of class dTDP acryloyl-CoA Ribonuclease PH (EC thymidine in DNA 2,4-dihydroxyhept- Beta-glucosidase nucleosides in DNA Beta-galactosidase deoxycytidines phosphinothricin N- NADPH-dependent 7-alpha-hydroxysteroid 3-hydroxyisobutyryl- phosphate Ribonuclease E N-acetyltransferase: N-acetyltransferase: 3-isopropylmalate transferase (EC GlpX type synthetase Adenylate kinase Dihydroorotate (EC 2.4.2.9): Uracil synthase (EC 2.5.1.47) CDS (EC mutase (EC phosphate deacetylase Deoxyguanosinetriphosphate Deoxyribodipyrimidine Serine tRNA Deoxyribodipyrimidine Glycine/D-amino 2',3'-cyclic-nucleotide α α II (coenzyme 2.7.7.56): Ribonuclease 2-ene-1,7-dioic acid (EC 3.2.1.21): (EC 3.2.1.23): Beta- acetyltransferase: FMN reductase: dehydrogenase: 7- CoA hydrolase (EC 3.1.26.12): GCN5-related N- GCN5-related N- dehydrogenase -Kdo-(2->4)- -Kdo- (EC 3.1.3.11) (EC 1.1.1.271) (EC 2.7.4.3) CDS dehydrogenase (EC phosphoribosyltransferase (EC Phosphoglycerate photolyase (EC 4.1.99.3) hydroxymethyltransferase dimethylallyltransferase in DNA Deoxyribodipyrimidine acid oxidase: 2'-phosphodiesterase 2.4.1.227): UDP-N- Kdo -(palmitoleoyl)-lipid IV a 2,3- B12-dependent) Nucleoside diphosphate L-citrulline 5.4.2.1): 2,3- (EC 3.5.1.25): G1RHH-2599 triphosphohydrolase (EC 3.1.5.1) Beta-glucosidase photolyase (EC 4.1.99.3) galactosidase (2->6)-(lauroyl)-lipid IV 2 A : Fructose-1,6- PH (EC 2.7.7.56) CDS (EC 2.5.1.75): tRNA aldolase (EC 4.1.2.n4) photolyase (EC 4.1.99.3) phosphinothricin N- NADPH-dependent alpha-hydroxysteroid (EC 3.1.2.4): Ribonuclease E acetyltransferase acetyltransferase (EC 1.1.1.85): 3- acetylglucosamine- A GDP-4-dehydro-6- 1.3.3.1): G1RHH-2545 UMP bisphosphoglycerate- kinase (EC 2.7.2.3) : Deoxyguanosinetriphosphate : Deoxyribodipyrimidine (EC 2.1.2.1): Serine : Deoxyribodipyrimidine Glycine/D-amino (EC 3.1.4.16): 2',3'- dihydroxybenzoyl- a seryl-[EntF (EC 1.17.4.1): kinase (EC 2.7.4.6): cys N-acetylglucosamine-6- : 2,4-dihydroxyhept- (EC 3.2.1.21) CDS (EC 3.2.1.23) CDS acetyltransferase CDS FMN reductase CDS dehydrogenase CDS G1RHH-2634 (EC 3.1.26.12) CDS CDS CDS isopropylmalate bisphosphatase, deoxy-β-L-galactose UDP-α-D-glucuronate ADP PRPP methanethiol acetaldehyde : Phosphoglycerate a nucleoside diphosphate a ribonucleic acid photolyase (EC hydroxymethyltransferase (EC dimethylallyltransferase (EC photolyase (EC : Deoxyribodipyrimidine acid oxidase CDS cyclic-nucleotide -N-acetylmuramyl- [EntB aryl- L-seryl-carrier Ribonucleotide orotate Nucleoside diphosphate Cytidylate kinase (EC independent phosphate deacetylase 2'-deoxyguanosine triphosphate 6 37 (2R)-2-hydroxy-2- 3-hydroxy- GlpX type (EC a 2'-deoxycytidine N -dimethylallyladenosine 2-ene-1,7-dioic acid D-glucopyranose a pyrimidine D-galactopyranose 4-nitrophenol photolyase (EC N-acetylphosphinothricin H + NADPH FMN 7-oxolithocholate a ribonucleoside an mRNA fragment [+ 6 isozymes] [+ 6 isozymes] dehydrogenase (EC lipid II (meso GDP-L-fucose biosynthesis (from kinase (EC 2.7.4.6) kinase (EC 2.7.2.3) CDS a thymidine in DNA gly acetaldehyde a 2'-deoxycytidine methylamine glyoxylate carrier protein] protein] reductase of class II 2.7.4.25): Cytidylate 2-phospho- (EC 3.5.1.25): N- in DNA in tRNA methylbutanenitrile nucleoside in DNA isobutanoate 3'-phosphate 3-acetylamino-4- an N- diaminopimelate α-D-Kdo-(2->4)-α- synthetase UDP-glucose) Nucleoside Ribonucleotide pyruvate succinate semialdehyde in DNA 2-oxovalerate UDP-N-acetyl-α- (Kdo) -lipid A, cold adapted F6P Orotate dTTP kinase (EC 2.7.4.25) CDS guanine and D-glycerate 3-phospho-D-glycerate acetylglucosamine- hydroxybenzoate acetylarylamine 2 α containing) D-Kdo-(2->6)-lipid A (EC 1.1.1.271): UDP- -D-glucose Ribonucleotide diphosphate reductase of class D-mannosamine phosphoribosyltransferase Uridine monophosphate guanosine salvage II 6-phosphate UDP-glucose reductase of class II (coenzyme Enolase Glucose-6- GDP-L-fucose kinase (EC 2.7.4.6) (EC 2.4.2.10): Orotate 2,3-bisphosphoglycerate- D-galactosamine 6-phosphate II (coenzyme B12-dependent) kinase (EC 2.7.4.22): (EC an N-(2,3- phosphate synthetase dehydrogenase : Nucleoside phosphoribosyltransferase (EC independent B12-dependent) Uridine monophosphate 4.2.1.11): D-galactosamine-6- dihydroxybenzoyl)- isomerase (EC 1.1.1.271) (EC 1.1.1.22): diphosphate (EC 1.17.4.1): guanosine phosphoglycerate kinase (EC 2.7.4.22) Enolase α seryl-[EntF L-seryl- UDP-glucose (EC 1.17.4.1): kinase (EC 2.7.4.6) Ribonucleotide Inosine-uridine preferring phosphate deaminase/ p-nitrophenyl- -D- a dimer of N-acetyl-D- D-gluconate (EC 5.3.1.9) mutase (EC 5.4.2.1): 2,3- phosphatidylglycerophosphate α α + GDP-β-L-fucose Ribonucleotide (EC a 1,4- -D-glucan maltopentaose an -D-galactoside 4-methylumbelliferyl glucoside pyrithiamine ν an organic molecule carboxynorspermidine a 9S rRNA scopolin FMNH NAD (R)-2-hydroxyglutarate an aminopeptidase N-ethylglycine reduced riboflavin maltotriose dehydrogenase reductase of class II UDP isomerase: G1RHH-2602 galactopyranoside non-adjacent h 2 mannosamine 6-phosphate a trypsin substr carrier protein] : Glucose-6- orotidine 5'-phosphate nucleoside hydrolase (EC bisphosphoglycerate- (1-octadecenoyl(9Z), 2-palmitoyl) substrate reductase of class II 4.2.1.11) Alpha-glucosidase AglA: Alpha-glucosidase AglA: Alpha-galactosidase Alpha-galactosidase Possible hypoxanthine Ribonuclease E D-2-hydroxyglutarate Glycine/D-amino N-acetylmannosamine Alpha- (EC 1.1.1.22) 3.2.2.1): Inosine-uridine Phosphatidylglycerophosphatase Beta-glucosidase Thiaminase II thymidines in DNA Deoxyribodipyrimidine Carboxynorspermidine Beta-glucosidase NADPH-dependent aminopeptidase: NADPH-dependent phosphogluconate phosphate UDP-α-D- Ribonucleotide Nucleoside diphosphate CDS independent D-tagatofuranose 6-phosphate (EC 3.2.1.22): Alpha- preferring nucleoside Alpha-glucosidase AglA CDS Alpha-glucosidase AglA CDS (EC 3.2.1.21): (EC 3.5.99.2): (EC 3.2.1.22): Alpha- oxidase XdhD (EC 1.-.-.-) (EC 3.1.26.12): (EC 3.2.1.21): FMN reductase: dehydrogenase: D- acid oxidase: FMN reductase: kinase (EC 2.7.1.60): glucosidase dehydrogenase isomerase glucuronate reductase of class Orotidine 5'-phosphate kinase (EC 2.7.4.6): A (EC 3.1.3.27): photolyase (EC 4.1.99.3) decarboxylase, putative Peptidase B (EC D-glucopyranose a 1,4-α-D-glucan D-glucopyranose maltotetraose galactosidase Beta-glucosidase Thiaminase II galactosidase : Possible hypoxanthine Ribonuclease E Beta-glucosidase NADPH-dependent 2-hydroxyglutarate Glycine/D-amino NADPH-dependent N-acetylmannosamine AglA: Alpha- (decarboxylating): 6- (EC 5.3.1.9) II (coenzyme decarboxylase (EC 4.1.1.23) Nucleoside diphosphate guanine phosphoenol 2-phospho-D-glycerate Tagatose-6-phosphate Phosphatidylglycerophosphatase : Deoxyribodipyrimidine (EC 4.1.1.-): G1RHH-2087 3.4.11.23) CDS (EC 3.2.1.22) CDS (EC 3.2.1.21) CDS (EC 3.5.99.2) CDS (EC 3.2.1.22) CDS oxidase XdhD (EC (EC 3.1.26.12) CDS (EC 3.2.1.21) CDS FMN reductase CDS dehydrogenase CDS a proteinogenic acid oxidase CDS FMN reductase CDS kinase (EC 2.7.1.60) glucosidase phosphogluconate enterobactin B12-dependent) : Orotidine 5'-phosphate kinase (EC 2.7.4.6) pyruvate kinase AgaZ (EC A (EC photolyase (EC a peptide N-acetyl-D- D-glucopyranose a non galactosylated 2-(2-methylpyridin- 4-amino-2-methyl-5- norspermidine Enolase (EC 4.2.1.11): 2.7.1.144): G1RHH-2600 1-oleoyl-2-palmitoyl- α-D-galactopyranose D-glucopyranose 4-methylumbelliferone 4-nitrophenol D-galactopyranose superoxide an alcohol an rRNA fragment a 5S rRNA D-glucopyranose scopoletin H + NADH FMN 2-oxoglutarate amino acid ethylamine glyoxylate riboflavin AglA CDS dehydrogenase, (EC 1.17.4.1): decarboxylase (EC Xanthine-guanine Pyruvate a thymidine in DNA mannosamine D-ribulose a peptide 6-phosphate UTP Enolase (EC 4.2.1.11) CDS phosphatidylglycerol galactose acceptor 3-yl)ethanol pyrimidinemethanol Ribonucleotide phosphoribosyltransferase kinase 6-phosphate D-glucopyranose maltose UMP D-tagatofuranose 1,6-bisphosphate 5-phosphate dGDP reductase of class II CTP synthase (EC (EC 2.4.2.22): (EC phosphoenolpyruvate 6.3.4.2): G1RHH-2687 Xanthine-guanine 2.7.1.40): tagatose-1,6-bisphosphate dADP CTP phosphoribosyltransferase Pyruvate Pyruvate kinase (EC aldolase: G1RHH-2600 Nucleoside Hypoxanthine-guanine kinase 2.7.1.40): Pyruvate DHAP D-glyceraldehyde 3-phosphate L-4-hydroxyphenylglycine-L- a dimer of adjacent 2'- a 2-acyl-1-lyso- a dimer of adjacent cytidine 2',3'-cyclic uridine 2'3'-cyclic UTP D-gluconate a cytidine diphosphate phosphoribosyltransferase (EC kinase (EC 2.7.1.40) CDS maltohexaose maltoheptaose a β-D-galactoside 2-hydroxychromene-2-carboxylate hν hν stachyose NAD + NADPH N-acetyl-D-mannosamine neolinustatin linustatin a dietary all-trans-retinyl ester GSSH sulfite 3-methylmuconolactone Nucleoside arginyl-D-4-hydroxyphenylglycine- monophosphate monophosphate 6-phosphate 32 GTP 2.7.1.40) deoxycytidines in DNA phosphatidylethanolamine thymidines in DNA Nucleoside triphosphate in tRNA kinase (EC 2.7.4.6) diphosphate (EC 2.4.2.8): L-seryl-L 4-hydroxyphenylglycine Alpha-glucosidase AglA: Alpha-glucosidase AglA: Beta-galactosidase 2-hydroxychromene-2- Alpha-galactosidase N-acetylneuraminate Beta-glucosidase Beta-glucosidase Lipase (EC 2',3'-cyclic-nucleotide 2',3'-cyclic-nucleotide Rhodanese phosphogluconate pyruvate Deoxyribodipyrimidine Lysophospholipase Deoxyribodipyrimidine NAD(P) transhydrogenase: Muconolactone : Nucleoside Hypoxanthine-guanine CDS Trypsin domain protein: Alpha-glucosidase AglA CDS Alpha-glucosidase AglA CDS 2'-phosphodiesterase 2'-phosphodiesterase pyrophosphohydrolase kinase (EC 2.7.4.6) (EC 3.2.1.23): Beta- carboxylate isomerase: photolyase (EC 4.1.99.3) L2 (EC 3.1.1.5): photolyase (EC 4.1.99.3) (EC 3.2.1.22): Alpha- G1RHH-1796 G1RHH-1797 synthase (EC 2.5.1.56) (EC 3.2.1.21): (EC 3.2.1.21): 3.1.1.3): Lipase domain protein: isomerase (EC dehydrogenase diphosphate Trypsin domain protein CDS (EC 3.1.4.16): 2',3'- (EC 3.1.4.16): 2',3'- MazG (EC 3.6.1.8): : Nucleoside D-glucopyranose maltopentaose D-glucopyranose maltohexaose galactosidase 2-hydroxychromene-2- : Deoxyribodipyrimidine Lysophospholipase : Deoxyribodipyrimidine galactosidase + : N-acetylneuraminate Beta-glucosidase Beta-glucosidase (EC 3.1.1.3) CDS G1RHH-2291 5.3.3.4),putative: (decarboxylating): 6- pyruvate D-4-hydroxyphenylglycine-L- NADP NADH Nucleoside triphosphate kinase (EC 2.7.4.6) diphosphate GMP L-4-hydroxyphenylglycine-L-arginine (EC 3.2.1.23) CDS carboxylate isomerase (EC 3.2.1.22) CDS synthase (EC 2.5.1.56) (EC 3.2.1.21) CDS (EC 3.2.1.21) CDS cyclic-nucleotide cyclic-nucleotide [+ 2 isozymes] phosphogluconate seryl-L 4-hydroxyphenylglycine photolyase (EC L2 (EC 3.1.1.5) CDS photolyase (EC a fatty acid all-trans-retinol G1RHH-1941 a 2'-O- a non galactosylated two adjacent 2'- sn-glycero-3- two adjacent UMP 4-methyl-3-oxoadipate- kinase (EC 2.7.4.6) D-galactopyranose α-D-galactopyranose raffinose N-acetyl-β-neuraminate D-glucopyranose lotaustralin D-glucopyranose linamarin 3'-cmp 3'-UMP thiosulfate glutathione dehydrogenase, methylcytidine trans-O-hydroxybenzylidenepyruvate a carboxylate D-ribulose galactose acceptor deoxycytidines in DNA phosphoethanolamine thymidines in DNA enol-lactone in tRNA

dGTP dATP 5-phosphate

(S)-lactate (R)-lactate

a siderophore a branched- a branched- a branched- a sulfonate a sulfonate a siderophore a dicarboxylate an Fe 3+ Fe 3+ a branched- an inositol L-alanyl-γ-D- maltotriose maltotriose an amino a dicarboxylate an sn-glycerol sn-glycerol chain chain chain an amino an amino an amino maltose maltose nitrate nitrate α-D- a nucleoside an an an oligopeptide an N-acetylneuraminate N-acetylneuraminate N-acetylneuraminate glutamate a capsular glycerol chain an inositol an inositol glutamyl-meso- maltotetraose maltotetraose maltotriose acid phosphate phosphate phosphate phosphate a maltodextrin a maltodextrin a 2,3,4-saturated fatty acyl CoA a 2,3,4-saturated fatty acyl CoA tungstate a dicarboxylate a dicarboxylate oligopeptide anguibactin anguibactin a capsular amino acid amino acid amino acid N-acetyl-α-D- N-acetyl-α-D- a C4- a C4- a C4- a C4- a C4- a C4- a C4- a C4- a C4- a C4- a C4- an inositol phosphonate a polyamine acid acid acid spermidine spermidine spermidine maltose pyrimidine oligopeptide oligopeptide oligopeptide oligopeptide polysaccharide 3-phosphate 3-phosphate phosphonate phosphonate phosphonate homoserine diaminopimelate a tricarboxylate an amino phosphate maltose cis-vaccenoyl-CoA cis-vaccenoyl-CoA hydrogencarbonate hydrogencarbonate xylopyranose malonate a capsular sn-glycerol 3-phosphate amino acid dicarboxylate dicarboxylate dicarboxylate dicarboxylate maltotetraose a xenobiotic maltose (indol-3- (indol-3- 2'-deoxyribose malonate polysaccharide chromate glucosamine glucosamine ammonium ammonium dicarboxylate dicarboxylate dicarboxylate dicarboxylate dicarboxylate dicarboxylate dicarboxylate a polysaccharide a polysaccharide tetracycline lactone a lipopolysaccharide acid Putative polysaccharide yl)acetate yl)acetate ABC iron putative TRAP TRAP Oligopeptide Inositol Maltose/ Maltose/ Maltose/ Maltose/ predicted predicted TRAP-type TRAP-type TRAP-type High- Branched- Branched- Inositol Inositol predicted ABC-type predicted ABC Xylose ABC predicted siderophore siderophore predicted dicarboxylate dicarboxylate TRAP TRAP Oligopeptide/ Oligopeptide/ Oligopeptide transport Oligopeptide Glutamate Ferric Ferric predicted ABC Glycerol-3- Glycerol-3- Glycerol-3- ABC-type transport Inositol predicted Probable Oligopeptide/ maltodextrin maltodextrin Maltose/ predicted Multidrug cell amino Amino ABC ABC ABC Phosphate Glycerol-3- Phosphate Phosphate Probable Maltose maltodextrin Maltose maltodextrin Maltose/ Long- Long- ABC ATP-driven transport transport transport Capsular Capsular affinity chain chain N-Acetyl-D- N-Acetyl-D- TRAP-type C4- TRAP-type C4- TRAP-type C4- TRAP-type C4- TRAP-type C4- TRAP-type C4- TRAP-type C4- TRAP-type C4- TRAP-type C4- TRAP-type C4- TRAP-type C4- transport transport predicted ABC predicted ABC predicted ABC Capsule Polysaccharide Tetracycline Tricarboxylate ABC Auxin efflux Auxin efflux Putative nitrate/ transporter of transporter, ABC transporter, transport ABC transporter, transporter, dicarboxylate dicarboxylate dipeptide dipeptide ABC system transport transport malonate malonate anguibactin anguibactin transporter phosphate phosphate phosphate Chromate branched- Ammonium Ammonium system transport ATP-driven homoserine/ dipeptide Lipopolysaccharide transport transport maltodextrin ABC resistance Amino acid processes; acid ABC acid ABC transporter, transporter, transporter, ABC phosphate transport transport low-affinity maltodextrin transport maltodextrin transport maltodextrin chain-fatty- chain-fatty- transporter transporter system, system, system, polysaccharide polysaccharide branched- amino acid amino acid glucosamine glucosamine dicarboxylate dicarboxylate dicarboxylate dicarboxylate dicarboxylate dicarboxylate dicarboxylate dicarboxylate dicarboxylate dicarboxylate dicarboxylate system system transporter of transporter of transporter of polysaccharide export efflux transport transporter carrier family carrier family deoxyribose- sulfonate/ nitrate/a sulfonate/ permease transporter fused system transporter DctM subunit, DctQ subunit, transporter, transporter, uptake uptake transporter, permease system membrane- transporter transporter transport transport of a capsular ABC ABC transport- transporter chain transporter transporter sugar- system ATP- transporter of homoserine uptake ABC transporter, ATP-binding ATP-binding transport transporter protein permease transport transporter, transporter, periplasmic periplasmic periplasmic transporter, ABC system system inorganic transport ATP-binding transport ATP-binding transport acid--CoA acid--CoA of a of an small small small export system ABC transporter, chain transport transport ABC transport ABC transport transport transport transport transport transport transport transport transport transport transport transport sugar- permease phosphonate phosphonate phosphonate export protein lipoprotein Wza protein TetA protein TctC of an protein protein specific ABC bicarbonate hydrogencarbonate component of tungstate permease permease of pyrimidine unknown unknown DctM DctQ family ABC family ABC periplasmic protein OppC permease spanning system system polysaccharide transporter, transporter, related amino acid binding binding phosphonate lactone family ABC protein MalK protein MalK ATP-binding of a polyamine norM of small periplasmic binding spermidine spermidine spermidine periplasmic transporter, permease permease phosphate ATP-binding protein MalK ATP-binding protein MalK ATP-binding ligase (EC ligase (EC nucleoside oligopeptide permease permease permease amino acid system system binding protein amino acid and ATPase protein substrate 3 substrate 3 (TC 3.A.1.5.1) protein (EC 3.6.3.19) (EC 3.6.3.19) (EC 3.6.3.19) (EC 3.6.3.19) α α domains malonate malonate chromate N-acetyl- -D- N-acetyl- -D- ammonium ammonium a C4- a C4- a C4- a C4- a lipopolysaccharide an amino a sulfonate a sulfonate α-D- a capsular glycerol a branched- a C4- a C4- a C4- a C4- a C4- a C4- a C4- phosphonate L-alanyl-γ-D- maltotriose a tricarboxylate a maltodextrin a maltodextrin 2'-deoxyribose pyrimidine an an an an a capsular a capsular sn-glycerol sn-glycerol a branched- a branched- a branched- glucosamine glucosamine phosphonate phosphonate acid an amino an amino maltose a 2,3,4-saturated fatty acid a 2,3,4-saturated fatty acid (indol-3- (indol-3- xylopyranose tungstate a dicarboxylate a dicarboxylate an polysaccharide sn-glycerol 3-phosphate dicarboxylate dicarboxylate dicarboxylate dicarboxylate dicarboxylate dicarboxylate dicarboxylate dicarboxylate dicarboxylate dicarboxylate dicarboxylate an inositol phosphonate a polysaccharide a polysaccharide tetracycline maltotetraose a polyamine an amino spermidine spermidine spermidine phosphate phosphate phosphate phosphate maltose nitrate nitrate a nucleoside oligopeptide oligopeptide oligopeptide an oligopeptide N-acetylneuraminate N-acetylneuraminate N-acetylneuraminate glutamate polysaccharide chain an inositol an inositol homoserine glutamyl-meso- maltotriose maltotriose an amino maltose cis-vaccenate cis-vaccenate a siderophore a dicarboxylate a dicarboxylate oligopeptide anguibactin anguibactin polysaccharide 3-phosphate 3-phosphate chain chain chain an inositol a xenobiotic acid acid acid phosphate maltose maltose yl)acetate yl)acetate hydrogencarbonate hydrogencarbonate oligopeptide amino acid lactone diaminopimelate maltotetraose maltotetraose acid a siderophore Fe 3+ Fe 3+ amino acid amino acid amino acid