Annual Report 2007-08
National Institute for Interdisciplinary Science & Technology Thiruvananthapuram Published by : The Director National Institute for Interdisciplinary Science & Technology Thiruvananthapuram Editorial Committee : Dr. B.C. Pai (Chairman) Dr. K. George Thomas Dr. T.P.D. Rajan Dr. C.H. Suresh Dr. Rajeevkumar Sukumaran Dr. (Mrs.) P. Nisha Dr. V.G. Mohanan Nair (Convener) Photography : Mr. P. Vijayakumar Design & Printing : Akshara Offset, Thiruvananthapuram
National Institute of Interdisciplinary Science & Technology Council of Scientific and Industrial Research Industrial Estate P.O. Thiruvananthapuram - 695019, Kerala, INDIA Tel:+91- 471- 2490674 / 2490811 / 2490224 Fax : +91- 471- 2491712 Email: [email protected], [email protected] CONTENTS
R&D Highlights 1
Agro-processing & Natural Products
Biotechnology Division
Chemical Sciences & Technology Division
Materials & Minerals Division
Process Engineering & Environmental Technology
Research Planning & Business Development
Library & Informatics
General Information
FOREWORD
t is a pleasure for me to present the Annual Reeport of the Institute Ifor the period 2007-08. This is a very momentous and productive year for the Institute in several aspects; a) The Institute was transformed from Regional Research Laboratory (RRL) to National Institute for Interdisciplinary Science & Technology (NIIST) ; b) A major chilly processing plant was dedicated to Nation on 21-3-08 by Hon’ble Minister for Commerce Shri Kamal Nath based on the technology developed in the laboratory in Byadgi Karnataka.; c) A technology package on production of synthetic rutile from illmenite was handed over to Cochin Minerals & Rutiles Ltd. By DG, CSIR as a part of technology transfer; d) The Institute has received the second Shanti Swarup Bhatnagar Prize in Chemical Sciences for the year 2007; e) The first CSIR young scientist award was received in the Institute in the area of chemical sciences.
This year we have published 210 SCI research papers with an average impact factor of 2.57 which is significantly higher than CSIR Average. An ECF of 8.07 lakhs per scientist and an average of 2.67 research papers per scientist are achieved for the year. On the infrastructure front, a High Resolution 500 MHz NMR facility has been created to cater the needs of our Chemical Sciences and Agroprocessing Divisions. Overall this year has been particularly productive which is apparent from the R&D highlights presented in this report. I congratulate all the staff members who have made this possible and happy that they will strive hard to sustain this growth in the coming years.
Prof. T. K. Chandrashekar NATIONAL INSTITUTE OF INTERDISCIPLINARY SCIENCE & TECHNOLOGY Thiruvananthapuram 6 6 ANNUAL REPORT 2007-2008 7 7 The Institute obtained approvals for six network projects and one project each under supra- The first year of the Eleventh Five Year Plan was one of most productive years for the Institute. the for years productive most of one was Plan Year Five Eleventh the of year first The HIGHLIGHTS OF NIIST ANNUAL REPORT 2007-08 REPORT NIIST ANNUAL OF HIGHLIGHTS national initiative on metal based drugs was also initiated during this year. national initiative on metal based drugs and related diseases in collaboration with CCMB & RGCB with financial support of DST under the development of novel infrared absorbing molecules and complexes for photodynamic therapy of cancer of therapy photodynamic for complexes and molecules absorbing infrared novel of development and international research organizations, academic institutions and industries. A major project on during the XI Five Year Plan at a total cost of Rs. 24.63 crores. Collaborations continued with national with continued Collaborations crores. 24.63 Rs. of cost total a at Plan Year Five XI the during institutional, inter agency and societal categories from the Planning Commission for implementation more than 2 per paper), patents filed (79 US), generation of ECF (more than Rs 48 crores), etc. more than 2 per paper), patents filed per scientist, in terms of number of high impact factor publications (890 numbers with average IF The analysis for the period 2002-2008 showed that it performed well with lower budgetary support papers per scientist, the Institute now ranks at position two among the CSIR labs in its performance. youngsters during the last few years started yielding fruits. In terms of quality publications and SCI infrastructure, quality systems, reorganization of divisions, and introduction of innovative and trained and innovative of introduction and divisions, of reorganization systems, quality infrastructure, Initiatives taken for the technological up-gradation of the R&D facilities, creation of state-of-art NATIONAL INSTITUTE OF INTERDISCIPLINARY SCIENCE & TECHNOLOGY Thiruvananthapuram 8 8 ANNUAL REPORT 2007-2008 9 9 Highlights involved in the development of development the in involved
Scientists
DG handling over technology document to CMRL DG handling over technology document ited (CMRL) by Prof. S.K. Brahmachari, Director General, CSIR at a function organized function a at CSIR General, Director Brahmachari, S.K. Prof. by (CMRL) ited Two commercial plants Two of capacity 50 tons per day red palmolein were established through As a part of the institutional efforts to commercialize the know-how developed in house, the As a part of the institutional efforts to commercialize the know-how One of the major technological achievements was the handing over of the technology for the for technology the of over handing the was achievements technological major the of One project engineering companies based on the technology nutrients micro developed the of by 75% than laboratory. more In that these so conditions plants, controlled under out carried is process refining laboratory took up the task of setting up a 20 TPD fresh chilli processing facility at Byadgi for M/S STCL, M/S for Byadgi at facility processing chilli fresh TPD 20 a up setting of task the up took laboratory the in up come to unit such first the is and crores 2.5 Rs of cost a at up set was facility This Karnataka. country for processing fresh chilli. Minister of State for Trade and Commerce, Govt. of India, Shri variety Bydagi The 2008. 21, March on nation the to plant processing the dedicated Ramesh Jayaram which are light sensitive. The of chilli is known for its high colour due to the presence of carotenoids technology ensures the drying operation in 20 minutes the at to adhering controlled dirt and conditions pesticide surface removes to which pre-washing ensure with along higher retention carotenoid farmers. material. The product fetches higher price giving better return to the R&D output and its commercialization R&D output and commercialization of a new process for the production of synthetic rutile from ilmenite to Cochin Lim Rutile and Minerals technology. This is one of the biggest technology transfers in the history of CSIR taking into environment impact and quantum of royalty payable. capacity of production, level of investment, view the at NIIST on January 16, 2008 in the presence of the Director and Director the of presence the in 2008 16, January on NIIST at NATIONAL INSTITUTE OF INTERDISCIPLINARY SCIENCE & TECHNOLOGY Thiruvananthapuram 10 10 NIIST in developed technique the by achieved was <200nm to nm 1500 from reduction size pore the and the pilottests. were evaluated and the rice quality was unaffected in blind tests. A full scale unit is planned based on Kalady.Pavizhamin at Mill Ltd., Rice Consortium Mill Rice Kalady Twelve paddy of batches successive process waseconomicallyviable. pozzolan for the concrete particularly for its chloride ion resistance. The cost excellent analysis showed that an the was produced material the that showed Tests 2008. March in Delhi New BMPTC, M/s 59 Tons per day (TPD) rice husk processing plant. The process know how was transferred to the sponsor, The designcanbeiterativelyrefinedusingfurthersimulations. feeding section, a genetic algorithm finds a every class For of feeder calculated. dimensions is such that feeder the the yield of is size maximized. the section, feeding a of modulus and volume the From feeder. separate a requiring section” “feeding a being cluster each clusters into casting the divides of analysis based initial design of feeders by integrating the complementary strengths of the rigorous heat transfer Institute, the by earlier entrepreneurs inArunachalPradeshandMizoram. with signed also were agreements transfer technology Similar Sikkim. of Government Department, spice processing facility in the state of Sikkim was signed with Horticulture and Cash Crops Development (TMOP) andeachplantprovidesdirectemploymenttoabout30people. Pulses and Oilseeds on TechnologyMission by supported was programme This problem. deficiency A vitamin address to oil nutritional a as used be can This trienols. toco and tocopherols ß-carotene, in rich is palmolein Red since society the to significant is contribution The lost. is oil palm in present nutrients micro the all where process refining normal the in unlike product end the in retained are . A prototype of all ceramic membrane setup for water filtration was successfully tested at BHEL by up set was plant pilot mills rice parboiled for developed was process zero-discharge A A commercial process design has been done to produce 10 TPD of reactive microsilica from a A new software was developed to overcome the limitation of the simulation software developed An agreement for technology transfer and licensing of knowhow for setting up of an integrated Virtual Casting Virtual Virtual Casting. Virtual and practically derived design rules. A novel pattern recognition algorithm recognition pattern novel A rules. design derived practically and The new software called software new The Virtual Feed, Feed, Virtual creates a simulation- a creates Highlights ANNUAL REPORT 2007-2008 11 11 matrix 2 Highlights were synthesized having colours ranging from white to brick red. The brown red ceramic 4 During the year the Institute published over 230 research papers in various national and The laboratory’s reverse flow natural convection driers have found extensive applications in Al-SiC functionally graded prototype brake rotor discs containing 20% SiC particle were are gels These colors. different of light emit which designed was materials soft of class new A detoxification for suitable acid) (Chlorendic concept Template Dummy utilizing beads micro MIP Novel environmentally secure inorganic pigments by doping praseodymium into CeO Publications & Patents Publications seminars/ different in presentations poster and papers several contributed and periodicals international of TiCeO coating surface various for pigments toxic existing to alternative interesting be to found were pigments applications. the rural areas for drying agricultural products. The driers are Driers and called five RRLT-NC models already are being used by farmers, cottage scale units, self employed persons etc for the drying of domestic for drier a developed has laboratory the Presently materials. other and agricultural of variety drying accelerated for drier A sheets. rubber drying for version cost low modified a and drying laundry undergoing is batch per coconuts whole of numbers 300 of scale a at copra ball make to coconuts of repeat trials. developed by vertical centrifugal casting and successfully road tested by an automobile conventional to compared efficiency braking industry. closer with good very was disc the of integrity Structural cast iron disc. ideal scaffolds for the design of supramolecular light- harvesting assemblies and are potential two- photon-absorbing materials, which could open the window to a novel class of electronically active optical properties soft organic materials with tunable removed beads MIP washed methanol The prepared. were waters natural contaminated endosulfan of endosulphan present in contaminated natural waters down to levels much below the of detoxification for forerunner a maximum be will concept This ppb. 20 ie. WHO by stipulated level permissible other deadly toxins like persistent organic and inorganic pollutants(POP’s & PIP’s), actual chemical and radionucleide. warfare agents(CWA’s) NATIONAL INSTITUTE OF INTERDISCIPLINARY SCIENCE & TECHNOLOGY Thiruvananthapuram 12 12 conferences heldarelisted below: staff and students to get an exposure to the recent developments in related subjects. Some important were alsocelebrated. week, Hindi “Radiance07”, Diwas/week, Staff Republic club day day, Independence day, Students day awareness Vigilance staff. the enlightened personalities eminent which in Day Science National and Events/Seminars/Symposia and staffofacademiaindustry. degrees from different universities. The Institute also extended short-term training facilities to student More than100researchstudentspursuedtheirworkfordoctoraldegreeand26receivedPh.D. members as well as students were deputed for various training programs/seminars/symposia/conferences. techniques for the staff are considered very essential for sustained growth. During the year, many staff Human Resource Development conferences/seminars alsoreceived“BestPaper Awards”. international and national in students and staff the by presentations paper/poster Many BARC. IANCAS, by Award” Thesis Best Arnikar H.J. Prof. the got Gladis Mary Dr.J. Sci.), (Chemical Award Young CSIR Scientist the received Dr. Bangalore, Jayakannan Sciences, M. of Academy Indian the of Pascal, Dr Suresh Das received the MRSI Medal 2007, Dr.Blaise, K. of Univ.George from Thomas has Degree been Doctorate elected as Honorary Fellow the received Pandey Ashok Dr. 2007, Medal MRSI and Fellowship Ramanna Science, Chemical in Prize Bhatnagar Swarup Shanti of recipient the was Ajayaghosh Dr. A. Medal, Silver CRSI awarded T.K.was Prof.Chandrashekar, Director achievements. Honors andAwards patents during thereportingyear.Indian 11 and foreign 6 of grant and patents Indian 6 and foreign 7 of filing in reflected appeared as cover page in reputed journals. The success of Institute’s innovative approaches was well symposia and conferences. The average impact factor increased to 2.57. A few of the publications also Many seminars and conferences arranged during the period gave an opportunity to the scientific The Institute Day, Foundationcelebrated CSIR National technology Day, NIIST Foundation Day latest and tools advanced approaches, management of use the to exposure and Training and work meritorious their for bodies different by awarded were scientists NIIST Several Highlights ANNUAL REPORT 2007-2008 13 13 Highlights Inaugural function of International Conference on Advanced Materials and Composites Inaugural function of International Conference International conference on “Advanced materials and composites (ICAMC-2007)” on “Advanced International conference on “New horizons in biotechnology” International Conference materials research” on “Recent trends in molecular joint conference DST-JSPS on “Frontiers in chemistry-2008” One Day Symposium and dioxin control” Seminar on “Solid waste management NATIONAL INSTITUTE OF INTERDISCIPLINARY SCIENCE & TECHNOLOGY Thiruvananthapuram 14 14 x…π{……n˘x… |…EÚ]ı EÚ™……Ω˲* |…EÚ…∂…x…Â) °Ú…<«±… EÚB M…B {…‰]‰ıx]Âı ( {…‰]‰ıx]Âı M…B EÚB °Ú…<«±… |…EÚ…∂…x…Â) +…<« +x…÷∫…∆v……x…{…j…E‰Ú®……®…±…‰®…Â∫…“B∫…+…Æ˙EÚ“|…™……‰M…∂……±……+…§…“S… x…π{……n˘x…∫…∆∫l……x…EÚ…‰ u˘i…“ |… ∂… I…i… x…¥…™…÷¥…EÚ…Â E‰Ú |…¥…‰∂… +… n˘ EÚ… +SUÙ… {… Æ˙h……®… |…n˘…x… EÚÆ˙x…‰ ±…M…… Ω˲* |…EÚ…∂…x…… EÚ“ =iEfiÚπ]ıi…… i…l…… |… ∫…∆∫l… ∫…‰ ¥…π……Á E÷ÚUÙ {…UÙ±…‰ i…l…… {…Ω˛±… M…B EÚB E‰Ú ±…B +… n˘ ∫…∆Æ˙S…x…… {…÷x…& EÚ“ |…¶……M…… {…r˘ i…, M…÷h…i…… ∫…fiV…x…, E‰Ú ±…Bx…⁄i…x… EÚÆ˙i…‰ Ω˲, |…i™…‰EÚ ∫…®…⁄Ω˛ EÚ… ∫…®…⁄Ω˛ |…i™…‰EÚ Ω˲, EÚÆ˙i…‰ EÚ…ÂGÚ“]ı, ¥…∂…‰π…i…™……: =x…E‰Ú ¥…∂…‰π…i…™……: EÚ…ÂGÚ“]ı, Ú {…n˘…l……Á E‰Ú ±…B Æ˙…∫i…… J…‰±…… Æ˙…∫i…… E‰Ú ±…B {…n˘…l……Á Ú … ]ı…‰EÚ…‰ ]≈ıx……ϱ… ∫…‰ ∫…®…fir˘ Ω˲* ∫…®…fir˘ ∫…‰ ]≈ıx……ϱ… ]ı…‰EÚ…‰ … (Al-Sic) ±……‰M…… EÚ…‰ Æ˙…‰W…M……Æ˙ EÚ… +¥…∫…Æ˙ |…n˘…x… EÚÆ˙i…… Ω˲* EÚÆ˙i…… |…n˘…x… +¥…∫…Æ˙ EÚ… Æ˙…‰W…M……Æ˙ EÚ…‰ ±……‰M…… ]ı“.{…“.b˜“ + ¶… GÚ™……∂…“±… ®…… 04 {…÷Æ˙∫EÚ…Æ˙|……{i…Ω÷˛BΩ˲* E‰Ú Ce 7 ¥…n‰˘∂…“ i…l…… 02 ®…Ë ]≈ıC∫… ®… |…… ∫…™……‰b˜…< ®…x…®… b˜…‰À{…M… u˘…Æ˙… ∫…°‰Ún˘ Æ∆˙M… ∫…‰ <«]ı-∫…… ±……±… Æ∆˙M… i…EÚ E‰Ú ¥… ¶…z… Æ∆˙M…… E‰Ú x…⁄ 300 ∫…∆{…⁄h…« x…… Æ˙™…±… EÚ…‰ §……ϱ… J……‰{…c˜… ®… {… Æ˙¥…i…«x… EÚÆ˙x…‰ ™…÷HÚ M… i…¥…Ãv…i… b≈˜…™…Æ˙ E‰Ú ¥…EÚ…∫… E‰Ú ∫…∆§…∆v… 6 ¶……Æ˙i…“™… {…‰]Âı]ı °Ú…<±… EÚB M…B i…l…… 2007 230 ∫…‰V™……n˘…+x…÷∫…∆v……x…EÚ…M…W……i…EÚ…|…EÚ…∂…x…Ω÷˛+…i…l…… ∫…‰ ∫…®®…… x…i… EÚ™…… M…™……* b˜…Ï. +∂……‰EÚ{……hb‰˜™… EÚ…‰ §±…‰∫… 6 ¥…n‰˘∂…“ i…l…… 11 ¶……Æ˙i…“™… {…‰]Âı]ı E‰Ú ±…B ∫¥…“EfiÚ i… |……{i… ˙ |…∫i…÷i…“EÚÆ˙h… E‰Ú ±…B ±…‰ +…ËÆ˙ BEÚ {… Æ˙¥…Ãi…i… ∞¸{… …B ¥…i…«®……x… ®… |…™…÷HÚ ¥…π…˱…‰ …ƒS… x…®…⁄x…‰ EÚ∫……x…, E÷Ú]ı“Æ˙ B* +…Ë∫…i…<∆{…ËC]ıM…÷h…j… Ú i…EÚ {……x…“ ®… ¥…i…«®……x… ®… {……x…“ Ú i…EÚ … V……i…… Ω˲* ¥…i…«®……x… ®… ¥…i…«®……x… Ω˲* V……i…… … “+…<«{…“) ¥……∫i… ¥…EÚ 2007 “{…“§…“ ∫…‰ ¶…“ x…®x… ®…‰Æ˙“ M±…… b˜∫… EÚ…‰ M±…… b˜∫… ®…‰Æ˙“ ®…÷J™… +∆∂… …∆¥…Ω˛x… b≈˜…™…Æ˙… EÚ… b≈˜…™…Æ˙… …∆¥…Ω˛x… Ω˲* |……‰. ]ı“. 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The seeded. de then and drier bed fluid the in dried reduced, size washed, is material raw The The Byadgi Chilli, which is known for its high colour is currently processed in the traditional As part of the institutional efforts to commercialize the know how developed in house, the Laboratory to assist the State Horticulture unit. Department to set up the processing signed agreements Transfer Technology Similar and Pradesh Arunachal in entrepreneurs with Mizoram NIIST signed a technology transfer agreement transfer technology a signed NIIST for setting up an integrated Spice processing and Turmeric Ginger, Fresh processing for unit Large Cardamom in the State. are interlocked and the manpower requirements are marginal. High pressure steam is used as the contact time in the drier is less than 15 minutes and the entire operation is automatic. All the machineries the All automatic. is operation entire the and minutes 15 than less is drier the in time contact to the conventionally processed raw material. acceptable levels. The resulting end product will have a 10 % increase in colour value when compared when value colour in increase % 10 a have will product end resulting The levels. acceptable processes fresh chilli hygienically and employs a fluid bed drier for bringing down the moisture to made functional by Jan 2007. manner which result in loss of carotenoids during the sun drying operation. The new facility created stone for the plant was laid by Pandala, Chairman Mr. State trading Corporation and the plant was laboratory took up the task of setting up a 20 TPD fresh chilli processing facility at Byadgi. The foundation The Byadgi. at facility processing chilli fresh TPD 20 a up setting of task the up took laboratory 20TPD Chilli Processing Facility Commissioned at Byadagi Facility 20TPD Chilli Processing that the interesterified blends contained ß and ß' polymorphic forms. blends contained ß and ß' polymorphic that the interesterified (4318- 9647ppm), oryzanols (3000-6800ppm) and carotene (121-180ppm). XRD studies demonstrated studies XRD (121-180ppm). carotene and (3000-6800ppm) oryzanols 9647ppm), (4318- EIE. The interesterified blends retained bioactive phytochemicals like tocols (839-1172ppm), sterols a considerable reduction in their highest melt peak temperature (TP) and solid fat content (SFC) on NATIONAL INSTITUTE OF INTERDISCIPLINARY SCIENCE & TECHNOLOGY Thiruvananthapuram 24 24 quantification (LOQ), robustness, recovery, precision etc. The method The etc. precision recovery, robustness, (LOQ), quantification of limit (LOD), detection of limit calibration, of terms in validated and developed were HPLC and HPTLC on based methods separate two standard, as THA isolated the Using MS. and NMR FTIR, by confirmed isolated in pure form from the seeds of Ayurveda and siddha. Tetrahydro amentoflavone (THA), a biflavone, was in inflammation cancer, disorders, hepatic and digestive including anacardium Semicarupus namely plants 2 remaining the in markers chemical of quantification for identificationaswellquantificationofmarkers. 2006-07) detailed investigations were conducted on 7 plants and methods were developed and validated (AR year last the During project. this of part as undertaken also was ”Bhasmas” of characterization physico-chemical Besides, standardization. based marker the for formulations their and plants 9 formulations for their biopotency through pharmacological and clinical trials. NIIST had been assigned identification and quantification of the markers in the Ayurveda formulations for and (c) validation of the methods (b) quantification, their for methods of standardization and markers chemical of standardization and validation of selected plants used in Ayurveda with objectives as a) identification Golden Triangle Partnership Project (GTP). Marker basedstandardizationofselectedplantusedinAyurveda: people andindirectlybenefitalargenumberoffarmersensuringfairpricefortheproduce. 30 to employment direct provide will unit The Chilli. Fresh processing for country the in up come heating mediumandtheplantisengineeredtoensurehighthermalefficiency. 6 formulationswerealsodevelopedandvalidatedduringtheperiod. Valeriana wallichii ed f hs ln i ue fr raig vrey f disorders of variety a treating for used is plant this of Seed and identification the for developed were methods report, under period the During GTP, initiated jointly by Dept. of AYUSH, CSIR and ICMR with financial support from AYUSH for to unit such first the is this and crores Rs.2.5 approximately of cost a at up set is facility The and validated. Methods for identification and quantification of chemical markers in S . anacardium characterized and Agro-processing &Natural Products Agro-processing eiaps anacardium Semicarpus and ANNUAL REPORT 2007-2008 25 25 Agro-processing Products & Natural as well as estimation of THA in formulations were carried S. anacardium Formulation : 050GTP : : 0111GTP : 0107-0110GTP Marker compounds : : : 0121-0122GTP : : 0123GTP: Gingingerol, 2osarone B-asarone acid Valerenic l-asarone, B-asarone, valerenic acid E-guggul sterone and z-guggulsterone : Sesamin and sesamolin 9 formulations namely Dislipidemia (GTP 050), Medhya-6 0111), (GTP: TG 01(GTP 0107), TG Rhizome of the plant and its formulations are better known for known better are formulations its and plant the of Rhizome prints. The marker compounds identified and quantified in the formulations are the following: prints. The marker compounds identified and quantified in the formulations identification and quantification of marker compounds using HPTLC and HPLC including their finger conducting the studies The formulations contained 4 to 8 plants. Methods were developed for (GTP (GTP 0121), and Nirgundi Thailam (GTP0123) were received under the project from AYUSH for 02 (GTP 0108), TG 03 (GTP 109), TG 04 (GTP 0110), Shinganadaguggulu (GTP 012), Goshuradiguggulu 012), (GTP Shinganadaguggulu 0110), (GTP 04 TG 109), (GTP 03 TG 0108), (GTP 02 Identif ication and quantif ication of marker compounds in formulations AYUSH showed valerenic acid content of 100 to 300 ppm on dry basis. dry on ppm 300 to 100 of content acid valerenic showed AYUSH and HPLC, using standard valerenic acid. The rhizome samples from in the rhizome as the marker compound was standardized by HPTLC disorders. Method for identification and quantification of valerenic acid valerenic of quantification and identification for Method disorders. Valeriana wallichii Valeriana neuro other and epilepsy insomnia, anxiety, for efficacy therapeutic their seed and 3 formulations of thus developed was sensitive to detect THA at 1ppm level. Finger printing of methanol extracts of the of extracts methanol of printing Finger level. 1ppm at THA detect to sensitive was developed thus out using these methods. NATIONAL INSTITUTE OF INTERDISCIPLINARY SCIENCE & TECHNOLOGY Thiruvananthapuram 26 26 management: Evidence basedherbal/nutraceuticalproducts forpreventivehealthanddisease identified andquantified. also were kaempherol and isorhamnetin quercetin, of forms Free O-rhamnoside. isorhamnetin and kampherol-3-O-sophroside-7- and isorhamnetin-3-O-glucoside as glycosides of -7-O-rhamnoside isorhamnetin-3-O-glucoside isorhamnetin-3-O-glucoside-7-O-rhamnoside, isorhamnetin-3-O-sophroside-7-O-rhamnoside, quercetin-3-O-rutinoside, and rutinoside glycosides were identified and quantified: quercetin-3-O- sophroside-7-O-rhamnoside, quercetin-3-O- andthefollowing HPLC-DAD-ESI-APCI using done were flavanoids of profiling detailed The fraction. this in concentrated be to found were flavonoids and fraction acetate ethyl in compounds of class major the to contributed Phenolics composition. chemical their for profiled and fractionated further were activity maximum having extracts methanol kernel seed of fractions water and acetate Ethyl Chemical profilingofactivefractionsseabuckthornseeds This Sea buckthorn seeds were evaluated for their antioxidant activities using HPLC profileofmethanolextractformulationfordislipdimea(GTP 050)(asarones)at304nm Supra Institutional Project, Institutional Supra SIP 004 was approved with a total budget outlay of Rs. 820 Rs. of outlay budget total a with approved was 004 SIP Agro-processing &Natural Products Agro-processing in-vitro model systems. ANNUAL REPORT 2007-2008 27 27 and the other fraction exhibited high exhibited fraction other the and 3 methods. in-vivo Agro-processing Products & Natural and in-vitro Experimental DesignExperimental differentiated adiposities. Further studies are envisaged to establish their 3 Creation of state ofCreation the art of state culturecell facility Out of the 12 plants selected, studies are initiated on six plants for activity guided fractionation. guided activity for plants six on initiated are studies selected, plants 12 the of Out A clean room (class1000) facility for the preservation and culture of cell lines and supporting and lines cell of culture and preservation the for facility (class1000) room clean A Creation of a state of the art cell culture facility. Creation of a state of the art cell culture Establishment of a correlation between oxidation stress and genesis diseases like inflammation, like diseases genesis and stress oxidation between correlation a of Establishment cell line studies. (CVD) and diabetes based on cardiovascular diseases Development of formulations using active fractions/active principles from the plants selected for this studies. of the formulations by Validation fractions showed strong anti-proliferative activity against Hela S Hela against activity anti-proliferative strong showed fractions SIP012 were evaluated for their anticancer and antidiabetic properties in model cell lines. One of the of One lines. cell model in properties antidiabetic and anticancer their for evaluated were SIP012 oxidase inhibition activity and hence could be a potent anti-inflammatory agent. Two fractions of efficacy in other model systems. confirmed its identity and purity by spectral data. The compound was found to posses very high xanthine high very posses to found was compound The data. spectral by purity and identity its confirmed conventional method. A marker compound in pure form was isolated from SIP010, characterized and characterized SIP010, from isolated was form pure in compound marker A method. conventional purity (> 95%) was optimized for SIP 008 and also with 20-25% higher recovery as compared to the purity (> 95%) was optimized for SIP 008 and also with 20-25% higher A new process at pilot scale to recover the active principle from the fresh plant material with high Rs.500 lakhs will be the first of its kind in the region for screening natural products for their activity. Rs.500 lakhs will be the first of its kind 2008. The cell culture facility supported with most advanced instrumentation with total investment of investment total with instrumentation advanced most with supported facility culture cell The 2008. anti-diabetic activity in 3T civil and electrical works were commenced and the facility is expected to be operational in September in operational be to expected is facility the and commenced were works electrical and civil instrumentation systems like confocal bio-imaging, flow cytometry etc are under establishment. The lakhs with main objectives as lakhs with main objectives NATIONAL INSTITUTE OF INTERDISCIPLINARY SCIENCE & TECHNOLOGY Thiruvananthapuram 28 28 of control flasks (specific activity: 141.48). Substrate bed thickness strongly influenced the production bed tray and column fermenters. Maximum enzyme yield (specific activity-146.34) was similar to that Alpha amylase: enzymes industrial of application and Development PROCESSESANDPRODUCTS DEVELOPMENT 1. BIO-BASED A A A eleventh fiveyearplannetworkedproject. activities were initiated on enzymes inhibitors and substrate specific amino peptidases under the of a new project on metagenomics by the Department of Biotechnology (DBT), New Delhi. New of two new projects. The activities in the area of biodiversity were strengthened with the sanction bioethanol program, The classified products. currently under their a for new area course of Energy,futuristic as got a processes boost bio-based with the adopt initiation to industries for need products development,2.Energy,and3.Healthgenomics.. and processes Bio-based 1. include which areas, major three has and development products A A r r r r r eas of eas of eas eas of eas eas of eas of eas A partnership link has been initiated with the TIFAC, New Delhi (and CII) to propagate the propagate to CII) (and Delhi TIFAC,New the with initiated been has link partnership A and processes Bio-based of theme the around centre Division the of activities R&D The content 50%,w/w). (starch bagasse cassava g/L 83 from acid) lactic to starch of conversion ~96% g/L; (40 producing non-fastidious of fusion protoplast by obtained fusant A usedforthecultivation. C-source that the BGL iso-forms in iso-forms BGL the that iso-forms and one of these was found to be glucose tolerant (GT-BGL). It was demonstrated Aspergillus crystallinus solid-state fermentationincomparisontoflasks. in culture fungal the by production enzyme the in increase substantial showed amylase alpha grade food of production the for designed bioreactor column model laboratory A glutamic acid,arginineandcitrulline:State-of-art scenario wassuccessfullycompleted. especially acids, amino of production the on US from project consultancy industrial An Resear Resear Resear Resear Resear Food grade alpha amylase production by c c c c c h & H & h H & h h & H & h BIOTECHNOLOGY DIVISION h & H & h H & h was shown to contain at least five different beta glucosidase (BGL) ighlights ighlights ighlights ighlights ighlights Bacillus amyloliquefaciens A crystallinus A were differentially expressed in response to the to response in expressed differentially were atbclu delbrueckii Lactobacillus Aspergillus oryzae showed high yields of L(+) lactic acid was carried out in packed and n amylase an ANNUAL REPORT 2007-2008 29 29 Biotechnology Division Biotechnology of the enzyme was determined was enzyme the of Vmax and Km produced by submerged fermentation was purified was fermentation submerged by produced with purified enzyme (50 U) for 3h Bacillus amyloliquefaciens Bacillus Fig. 1 Scanning electron micrograph of (a) raw rice starch (b) raw rice starch hydrolysed Under the Indo-Argentina bilateral cooperation project, the stability studies of lipase enzyme Under the Indo-Argentina bilateral cooperation project, the stability studies Alpha amylase of amylase Alpha levels, three factors were found to be significant. A central composite design with three factors at 5 fermentation conditions. Based on initial screening using a factorial design with 10 factors at two development studies for the lipase production were carried out in submerged and solid-state were performed at different temperatures and in hydrophilic and hydrophobic solvents. The process Biocatalysts- a novelBiocatalysts- forapproach the production of pharmaceuticals exhibited maximal substrate specificity for amylase. The amylase. for specificity substrate maximal exhibited the purified enzyme determined as 58 kDa and was confirmed by activity staining. The purified enzyme purified The staining. activity by confirmed was and kDa 58 as determined enzyme purified the purity with a the specific apparent activity molecular of weight 72 of was SDS-PAGE, obtained. From enzyme showed its effectiveness (Figure 1). hydrolysed with the partially purified to near-homogeneity by ion exchange Through chromatography. the process 38.6-folds increase in using both amylose and soluble starch as substrate. Scanning electron micrograph of raw rice starch by conical flasks and on contradictory growth were lower in column bioreactors. on contradictory growth were by conical flasks and for which aeration was not provided. Enzyme production was 48% higher by column bioreactor than bioreactor column by higher 48% was production Enzyme provided. not was aeration which for yield (specific activity-220.3) was obtained at 3.5 vvm. No growth was observed in the column fermenter column the in observed was growth No vvm. 3.5 at obtained was activity-220.3) (specific yield bed height of 17.5 cm for 72h showed the production at all aeration rates, but the maximal enzyme maximal the but rates, aeration all at production the showed 72h for cm 17.5 of height bed column bioreactor (22.5 cm × 4 cm) at different aeration rates from 1.5 vvm to 4.5 vvm with a fixed a with vvm 4.5 to vvm 1.5 from rates aeration different at cm) 4 × cm (22.5 bioreactor column and 2 cm or higher bed thickness resulted poor growth and enzyme production. Fermentation in NATIONAL INSTITUTE OF INTERDISCIPLINARY SCIENCE & TECHNOLOGY Thiruvananthapuram 30 30 sequences were aligned. The degenerate and specific primers for amplification from multiple and downloaded were database NCBI from sequences phytase The enzyme. fungal the in tolerance temperature and pH develop to project this supported has DBT fermentation, solid-state mutagenesis site-directed from phytase tolerant pH low and thermostable of Development Co of presence in min 60 about for thermostable by produced LAP enzyme. of activity relative the enhanced concentration CoCl CaCl salts, ion Metal 55ºC. and 50ºC of 8.5 – 9.0 and the temperature optima between range the in was activity LAP maximum the for conditions was 22.52 ± 0.14 IU/ml. pH optimum NaCl. The maximum LAP titer under the optimum and Tween80 of concentration temperature, incubation pH, initial were significantly influenced parameters The substrate. as (LAP) in submerged fermentation using soy flour producer of extra-cellular leucine aminopeptidase Streptomyces gedanensis production. aminopeptidase leucine L- cellular Streptomyces peptidases amino specific Substrate using statisticaldesignisunderprogress. factors of screening Further important. be to factors nine revealed fermentation submerged under levels was used to develop a quadratic model and validation of model is under progress. The screening 2+ at60ºC. 2 .6H2O, FeCl tan wr eautd o extra for evaluated were strains 2. 2H 2 O, and FeCl Aspergillus niger niger Aspergillus was found to be a good : In continuation to a completed project on the production of phytase in phytase of production the on project completed a to continuation In . gedanensis S. 3 .6H 2 O in 5mM : 2 Several 2H using was 2 O, attended theconference. countries overseas the from 107 including delegates, 607 of total A Biofuels. and Safety Food in Advances Ecology, Molecular Research, Mycobacterium Nanotechnology, on focussing mini-symposia five besides sessions four in and sessions 22 in lectures invited agricultural and medical biotechnology with 101 & food environmental, industrial, of areas programme of the conference focussed on thrust scientific The France. Blaise-Pascal, University Ferrabd, Polytech’Clermont Director, Dussap, The function was felicitated by Prof. Claude-Gilles of research. development the for fields various the between needed are efforts synergistic that emphasized and discovery drug for background important an provide will biotechnology that observed Sciences, Hyderabad, who inaugurated the event, Life of Institute Director, Iqbal, Javed Prof. November 26-30,2007. during Trivandrum at (BRSI) India Society, Fourth Annual Convention of the Biotech Research the (NHBT-2007)and Biotechnology in Horizons New on Conference International Organised NHBT-2007 Biotechnology Division Aspergillus niger 437 posters 437 ANNUAL REPORT 2007-2008 31 31 Psychrophilic yeast Psychrophilic Biotechnology Division Biotechnology Utilization of brown coir waste pith for the for pith waste coir brown of Utilization NRRL 2217 was used for solid-state fermentation for fermentation solid-state for used was 2217 NRRL Aspergillus oryzae Aspergillus (Director,NIIST), Dr J. Iqbal (Chief Guest), Dr M. R. Pillai (RGCB) and Prof L.V. Rao (BRSI Secretary) Rao (BRSI J. Iqbal (Chief Guest), Dr M. R. Pillai (RGCB) and Prof L.V. Dr (Director,NIIST), Prof A. Pandey (BRSI President), Prof C. Larroche (Blaise Pascal Univ, France), Prof. T.K. Chandrasekhar T.K. France), Prof. Prof A. Pandey (BRSI President), Prof C. Larroche (Blaise Pascal Univ, Address by Prof G.C. Dussap (Blaise Pascal Univ, France) at the inauguration of NHBT-2007. On dais (L to R): France) at the inauguration of NHBT-2007. Univ, Address by Prof G.C. Dussap (Blaise Pascal Lignin degrading enzymes production and application: application: and production enzymes degrading Lignin the over-expression of enzymes from the selected medium. the over-expression Neutral protease production: protease Neutral screened for the production of enzymes and cultural and nutritional parameters were optimized for Production, characterization and application of alpha and beta galactosidase: Production, characterization and application of alpha and beta galactosidase: were media Different galactosidase. beta for portion milk temperature low from isolated were strains fermented the from products added value of development and enzymes degrading lignin of production flasks could be well achieved. Scale-up studies using the trays showed that the enzyme yields as obtained in the lab studies in the model. The model showed that the fermentation time and temperature had a significant interaction. model. The model showed that the fermentation time and temperature neutral protease production using statistical design experiments employing the Box-Benkhen quadratic Box-Benkhen the employing experiments design statistical using production protease neutral amplification using degenerate primers was carried out. degenerate primers was carried amplification using were designed. The genomic DNA isolation protocol from fungal DNA was standardized and PCR NATIONAL INSTITUTE OF INTERDISCIPLINARY SCIENCE & TECHNOLOGY Thiruvananthapuram 32 32 such as rice straw, sugar cane bagasse and water hyacinth biomass were used as substrates for bioethanol feed-stocks, natural Different CSIR. of scheme NMITLI the under initiated was feedstock as biomass Bioethanol from lignocellulosic biomass: 2. ENERGY w/w) supplemented with yeast extract and peptone (0.2% each) and the buffering agent (2% CaCO 50%, content (starch bagasse cassava g/L 83 from v/v) (3%, inoculum fusant using by acid) lactic to Surface Methodology. During validation, 40 g/L of Response lactic acid and was obtained design (~96% conversion Plackett-Burman of starch using conducted was production acid lactic for parameters process important the of Optimization production. acid lactic L(+) for supplementation nutrient further studies. Selected fusant for could utilize selected the was liquefied cassava fusant bagasse starch best directly the with minimum and monitored was fusants few by production acid lactic fusion, non-fastidious and also to develop the tolerance to pH, etc. Protoplast fusion of Lactobacillus delbrueckii acid lactic L(+) of Production Bacillus sphaericus using fermentation submerged under PHB of production maximum the gave powder seed Jackfruit commercial enzymes and the hydrolyzates assessed for selecting the best substrate for PHB production. cake, groundnut oil cake, cassava powder, jackfruit seed powder and corn flour oil were hydrolyzed sesame using starch, potato bran, wheat viz., substrates, Seven source. carbon the as residues stocks The aim of this work was to study the production of polyhydroxybutyrate (PHB) using renewable feed- Polyhydroxybutyrate production using renewable feed-stocks as substrate by biopolymers of Production type microbial cultures for the production of specific enzymes under an industrial consultancy project. Production of nitrilase, reductase and hydantoinase: were screenedand of cultures The evaluated. was pith waste Bacillus amyloliquefaciens (19%)attheinitialpHof7.5. P. sajorcaju NCIM 2025. Genome shuffling method was adopted to increase its productivity wasselectedforsolid-statefermentationwithcoirpith. : L(+) lactic acid was synthesised as the monomer of polylactide by polylactide of monomer the as synthesised was acid lactic L(+) ATCC 23842 was carried out. After the third cycle of protoplast A new project on bioethanol production using lignocellulosic P.P.sajorcaju, P. sqarrulosus, florida Soil samples were screened for isolating wild- L. delbrueckii Biotechnology Division and an amylase producing Bacillus sphaericus: Bacillus and Ganoderma sp. 3 ). ANNUAL REPORT 2007-2008 33 33 This is a RUT C30 and C30 RUT A. crystallinus. A. T. reesei T. beta glucosidases could Biotechnology Division Biotechnology A. niger of ~200mM which qualified it as a Ki A crystallinus. A , and the studies on the properties of the enzyme: T. reesei Figure 3: Differential induction of BGLs in Lane 4: Glucose (SmF), Lane 8: WB(SSF), Lane 9: RS(SSF) Lane 1: WB (SmF) , Lane 2: RS (SmF), Lane 3: Cellulose (SmF) by SSF was continued, which showed that F5 BTC ded by the New DST, Delhi under the Scientists Young Fast scheme. Track Crude BGL A. niger tolerant. Degenerate primers were designed for amplification of the GT-BGL protein from protein GT-BGL the of amplification for designed were primers Degenerate tolerant. staining revealed the presence of at least five different BGL and at least one of which was glucose confirming that the enzyme was moderately glucose tolerant. Gel electrophoresis followed by activity primers. degenerate of sets 14 of design for used were blocks conserved and aligned domain, public from new project fun preparation from BTCF58 was showed that the Ki for glucose inhibition of the GT-BGL was 400mM downloaded were hydrolases glycosyl of V and III I, classes to belonging fungi filamentous of sequences BGL glucose was iso-form weight molecular low the that indicated glucose of presence in (4-MUG) substrate Glucose tolerance of the different BGL iso-forms test by incubating similarly processed gels with the production was achieved. The partially purified BGL showed a CBHI control elements from fungus was optimized using statistical design of experiments and a four-fold improvement in the Isolation and cloning of glucose tolerant beta-glucosidase from fungal isolate BTCF58 and the be differentially induced in response to carbon sources in the medium. Cellulase production by the glucose tolerant enzyme. saccharification efficiency and availability. Production studies for cellulases from cellulases for studies Production availability. and efficiency saccharification production. Rice straw and sugar cane bagasse were selected as potent feed-stocks based on BGL from NATIONAL INSTITUTE OF INTERDISCIPLINARY SCIENCE & TECHNOLOGY Thiruvananthapuram 34 34 new antibioticregimefor treatment oftuberculosiswithMDRstrains. species and their correlation with beta lactam and inhibitor susceptibility profile are useful in developing resistance against beta lactams. Systematic of study of spectrum wide giving activity like lactamase beta or lactamase beta having proteins producing in gene one than more of possibility the revealed study The resistance. increased an inhibition studies. Antibiotic susceptibility studies were performed using the recombinant strains showed enzyme the by followed derived were proteins recombinant the all for parameters Catalytic lactams. blotting and were shown to have beta lactamase activity by the hydrolysis of nitrocefin and other beta over expressed in C41 (DE3) tuberculosis tuberculosis: M. of lactamase beta of characterization biochemical and expression over cloning, Molecular Mycobacterium 3. HEALTH ANDGENOMICS glucose concentrations(Figure4) elevated of presence in activity showed iso-form this to corresponding band the only since tolerant H37 Rv, showing hypothetical beta lactamase activity were cloned in pET28a vector and vector pET28a in cloned were activity lactamase Rv,beta H37 hypothetical showing Three genes (Rv genes Three research Lanes 1,2,3:Control(NoGlucose),4,5:0.5MGlucose, Figure 4: Glucose tolerance of BGL isoformsin Figure 4:GlucosetoleranceofBGL E. coli Lanes 6,7:1MGlucose,8,9:1.5MGlucose 2068c . The His tagged recombinant proteins were confirmed by immuno- , Rv , 0406 c and Rv M. tuberculosis 3677 c) from the genome data bank of bank data genome the from c) A crystallinus beta lactamases and that of related Biotechnology Division M. tuberculosis M. M. ANNUAL REPORT 2007-2008 35 35 within M. tuberculosis affinity column. 2+ Mycobacterium H37Rv was overexpressed in overexpressed was H37Rv Biotechnology Division Biotechnology through pET28a expression vector expression pET28a through The survival of : E. coli E. involved in the synthesis of mannolipids in pmmB Mycobacterium tuberculosis Mycobacterium M. tuberculosis and manA, manB, pmmA Figure 5. Inhibition of peptide deformylase of M. tuberculosis by Actinonin were amplified, cloned and over-expressed in over-expressed and cloned amplified, were The peptide deformylase (PDF) from (PDF) deformylase peptide The C and pH of 7.5. Metal chelators like and EDTA 1, 10 Phenathroline completely abolished the as recombinant His tagged protein and purified by passing through the Ni o function relationship of this protein. deformylase, having some of their conserved sequences changed, were created to study the structure- the study to created were changed, sequences conserved their of some having deformylase, inhibitors against mycobacterial PDF is being standardized. Some site-directed mutants of peptide inhibited by the known peptide deformylase inhibitor actinonin and a method for screening of natural of screening for method a and actinonin inhibitor deformylase peptide known the by inhibited PDF enzyme activity at a concentration of 10mM.The recombinant PDF was shown to be completely H37Rv: be 30 that Km value was calculated to be 4 mM. The optimum temperature for activity of PDF was found to found was PDF of activity for temperature optimum The mM. 4 be to calculated was value Km that Mannolipids and mannose metabolism in E. coli The purified PDF was found active against the chemotactic peptide substrate N-formyl-Met-Ala and Four Four genes namely Molecular studies on peptide deformylase and methionine aminopeptidases of mannolipids of mycobacterial cell wall and mannose binding receptor (MBR) on macrophage cell wall. cell macrophage on (MBR) receptor binding mannose and wall cell mycobacterial of mannolipids proteins were in progress. the macrophages is possible due to the physiological interaction between mannan core (MC) in the tuberculosis M. recombinant expressed over of characterization biochemical detailed and Purification tagged. Histidine as NATIONAL INSTITUTE OF INTERDISCIPLINARY SCIENCE & TECHNOLOGY Thiruvananthapuram 36 36 to be activated by Mg p chromatographic steps. The purified Methionine aminopeptidase was found active against L-Methionine organism directly by routine purification steps involving ammonium sulfate precipitation and sequential DNA isolation was carried out. DNA yield was higher with the enrichment cultures. Quality of DNA was progress. in is clones of confirmation and library of screening Further strain. producing beta-lactamase with Chloramphenicol containing Luria agar plates. Approximately, 2000 colonies were screened plating by with pCCFos vector and packaged. The ligated and selected size repaired, end was DNA isolated The Kb. 30 was isolated DNA metagenomic metagenomic DNA’s were tested for restriction digestion by using isolated The standardized. was protocol isolation DNA and method PVP and SDS lysozyme/CTAB, of and lipases inhibitors beta-lactamase novel for libraries DNA environmental of screening and Construction Metagenomics and Feas such cations, the of Some actinonin. and amastatin bestatin, like, inhibitors aminopeptidases most ofthemethionineaminopeptidases. nitroanilide, a chromogenic substrate specific for Methionine aminopeptidases. The MetAP was found Cu 2+ Lipase producers were enriched in the soil sample for construction of metagenomic library and inhibited theMetAPfrom The methionine aminopeptidases (MetAP) of (MetAP) aminopeptidases methionine The : Beta-lactamase inhibitors: DNA extraction from soil samples was done using a combination 2+ from the apoenzyme state and not by Co M. smegmatis E. coli M. smegmatis cells were infected with packaged library and plated on . M. smegmatis M. M-Protein marker M-Protein 4- SephadexG-100fraction ionexchangefraction 3-Q-Sepharose 2-Ammonium sulfatefraction(50-60%) 1-Crude protein MetAP wasfoundtobeinhibitedbyknown 2+ Hin which is the reported cofactor for dIII enzyme. The average size of mc Biotechnology Division 2 155 was purified from the from purified was 2+ ANNUAL REPORT 2007-2008 37 37 ). Cell dry weight (g/l) weight dry Cell Two potent Two isolates, CB2 3 2.5 2 1.5 1 0.5 0 Biotechnology Division Biotechnology 120 ) and the growth profile of MC1( 96 à 72 The selected cultures were further screened for their ability their for screened further were cultures selected The Incubation time (h) Incubation 48 Lactic acid bacteria (LAB) were isolated from fermented vegetables, 24 a maximum production of 8.79± 0.05 g/l. and the yield increased up to 9 8 7 6 5 4 3 2 1 0 10 Exopolysaccharide (g/l) Exopolysaccharide with Figure 7. EPS production at various time intervals ( Metabolic engineering has been initiated for increased production of folate. Among the isolates the Among folate. of production increased for initiated been has engineering Metabolic the best is by MC1 (24.17 g/l) by performing statistical studies. two potent isolates, MC1 from yogurt and W3 from whey were found to be EPS producers, of which two potent isolates, MC1 from yogurt and W3 from whey were found folate. to produce nutraceuticals such as folic acid and exo-polysaccharide (EPS). intracellular and cellular extra both produce to found were dough) sour (from SD2 and cabbage) (from susceptibility pattern against antibiotics etc. antibiotics against pattern susceptibility of the resistance cell to surface, phenol emulsifying concentration, activity, antimicrobial activity and certain probiotic characteristics like bile salt resistance, salt tolerance, survival in low pH, hydrophobicity pH, low in survival tolerance, salt resistance, salt bile like characteristics probiotic certain sour dough, milk products, sheep, human excreta and yogurt. The isolated cultures were evaluated for evaluated were cultures isolated The yogurt. and excreta human sheep, products, milk dough, sour bacteria for novel applications: 1.6). Tests are being carried out for restriction digestion compatibility are being carried out for restriction digestion 1.6). Tests Metabolic activities and genetic manipulation leading to nutraceutical products from lactic acid chloroform extractions were attempted with some improvement in absorbance ratios (260/280=1.5- were attempted with some improvement chloroform extractions Probiotics components. Purification using gel purification kits as well as by classic methods of repeated phenol components. Restriction analysis was not successful implicating a probable interference with humic to be lower (260/280=1.3-1.5) for soil DNA indicating contamination with proteins and/or humic tested by performing absorbance ratio analysis and restriction digestion. Absorbance ratio was found was ratio Absorbance digestion. restriction and analysis ratio absorbance performing by tested NATIONAL INSTITUTE OF INTERDISCIPLINARY SCIENCE & TECHNOLOGY Thiruvananthapuram 38 38 optimization studiesforthefolateproductionareinprogress. levels. Extracellular and intracellular folate levels were detected for the selected isolates. Further process folate the detect to adopted were assay microbiological and HPLC derivatives. and acid folic produce to efficacy the for analyzed further be will ones selected the and characteristics probiotic underlying qualities their on based them screening sources, various from bacteria acid lactic of collection and Osmania University, and Hyderabad NIIST Trivandrum. The over all work for NIIST involves the isolation net work research programme involving three institutions such as North Maharashtra University, Jalgoan, Development of efficient probiotic to combat Vitamin B12, folic acid and iron deficiency: Biotechnology Division This is a ANNUAL REPORT 2007-2008 39 39 h h h h h c c c c c esear esear esear esear esear r r r r r eas of eas of eas of eas of eas of r r r r r CHEMICAL SCIENCE & TECHNOLOGY CHEMICAL complexes for photodynamic therapy of cancer and related diseases in collaboration with collaboration in diseases related and cancer of therapy photodynamic for complexes based metal on initiative national the under DST of support financial with RGCB & CCMB drugs. CSIR family. Efficient Devices”. NCL, Pune and CLRI, Chennai participating in this network project. Efficient Devices”. NCL, Pune and CLRI, Chennai participating in this network including plastic photochromic lenses, fixed-tint sunglass lenses, and camera and LCD projector lenses. J. Polym. Sci. and Macromolecules. J. Polym. Bangalore. been awarded the prestigious Shanti Swaroop Bhatnagar Prize for Chemistry. been awarded the prestigious Shanti Initiated a major project on development of novel infrared absorbing molecules and Participating in two other network projects being coordinated by other laboratories in the in laboratories other by coordinated being projects network other two in Participating Co-ordinating a major CSIR funded network project on “Organic Materials for Energy Collaboration with Corning SAS-France a leading manufacturer of a wide range of products of range wide a of manufacturer leading a SAS-France Corning with Collaboration MRSI medal-2007 by Dr. A. Ajayaghosh MRSI medal-2007 by Dr. Suresh Das. MRSI medal-2008 by Dr. Chem. Phys. J. Chemie, Angewandte as such journals leading in publications Pages Cover CSIR Young scientist award-2007 by Dr. M Jayakannan, scientist award-2007 by Dr. CSIR Young Dr. Dr. K. George Thomas has been elected as Fellow of the Indian Academy of Sciences, For the second For consecutive year A.a member Ajayaghosh of has the Division namely Dr. Photosciences and Photonics Organic Chemistry Materials Inorganic & Polymer ‘To be internationally recognized for excellence in discovering new knowledge about functional about knowledge new discovering in excellence for recognized internationally be ‘To • • • • • • • • • • • • • ighlights ighlights ighlights ighlights ighlights ision & A ision & A ision & A ision & A ision & A H H V V H V materials and natural products/bioactive molecules, and to develop such materials/molecules for industrial applications using innovative, cost competitive and environmentally acceptable processing technologies.’ H H V V NATIONAL INSTITUTE OF INTERDISCIPLINARY SCIENCE & TECHNOLOGY Thiruvananthapuram 40 40 td dmntae te xsec o cia setc (m* pae i a eis f symmetrical of bolaamphiphiles possessing series a diphenylbutadiene a core and in glucopyranoside head phases groups linked (SmC*) together C smectic chiral of existence the demonstrated study exhibit macroscopic chirality due to strong hydrogen bonding not between do sugar generally head in groups. sugars The present amphiphilic centers, chiral of presence the of spite in that literature the in known well is It attention. considerable attract (SmC*) C smectic chiral and nematic chiral phases, crystal liquid various the Among applications. technological of variety a for decades several past the Crystals Liquid SwitchingSmC* Photoactive SugarChirality Based in single crystalX-ray analysis( molecular packing of the material which could be characterized by studying the molecular packing by the in transformation a to attributed be could differences The fluorescence. distinguishable visually cyano-substituted diphenyl butadiene compounds as well as alkoxy phenyl-pyridyl compounds possessing determining in packing molecular of role The relationships. structure-property their predicting for fundamental is interactions these of knowledge depth in an and materials in organization molecular PackingMolecular 1. PHOTOSCIENCESANDPHOTONICS Liquid crystals (LCs) belong to a class of materials, which have been extensively exploited for exploited extensively been have which materials, of class a to belong (LCs) crystals Liquid controlling in role major a play aggregation as such interactions molecular Non-covalent Change influorescencewithdifference molecular packinginsolidstate. Vs Solid StateSolid Fluorescence J. Phys. Chem. 2008 ,112, 2137 Chemical Science&Technology between two polymorphic states of alkoxy- transformation reversible thermally of observation interesting the with by molecularaggregation.Thisworkdeals is quenched due to exciton coupling caused fluorescence state solid their synthesized, emission in solution have been designed and number of chromophores exhibiting strong a Although (OLEDs). diodes emitting light organic of design the in importance significant of is it and understood well not still is that area an is molecules organic of properties photophysical other and fluorescence state solid andJ.Phys.Chem. 2008 , 112, 8429). ANNUAL REPORT 2007-2008 . 41 41 Adv. Funct. Mater Funct. Adv. Chemical Science & Technology Science & Chemical by oligomethylene spacers exhibited the smectic spectra fluorescence and absorption The phase. C* of these materials suggest that the unusual observation of macroscopic chirality in these bolaamphiphiles containing free hydroxyl groups Photomodulated full color display device 2008) . Adv. Funct. Mater Funct. Adv. , 1632). A new class of soft materials was designed which emit light of different colors as shown in the in shown as colors different of light emit which designed was materials soft of class new A Chiral nematic (N*) LCs are especially attractive among liquid crystals, since in these systems 18 , Design of pi-Gels with Tunable Emission DesignTunable of pi-Gels with the to character electronic tunable a providing in role crucial a played moieties ester dipolar The figure. Photoresponsive N* Liquid Photoresponsive Crystals with Circulary Polarised Photoluminescence light, of reflection selective to lead which structures ordered helically into self-organize molecules the depending upon the pitch of the helix. The helical pitch of N* LCs is dependent upon various factors such as temperature, electrical, or magnetic field and on the nature and concentration of impurities, photo- work, present the In stimuli. external of variety a by color their tune to possible it makes which moieties cholesterol to linked core diphenylbutadiene a of consisting trimesogens responsive thermo and on either side via flexible alkyl chains were developed for display device fabrication. The pitch of the making photochemically, and thermally varied continuously be could materials these of phase cholesteric generated thus images color The region. visible entire the over film the of color the tune to possible it photoluminescent, highly also were materials These glasses. N* to them converting by stabilized be could polarized linearly by even state crystalline liquid glassy the in characteristics polarized circularly exhibiting excitation.( could be attributed to self aggregating behavior of the diphenyl butadiene core. ( 2008 NATIONAL INSTITUTE OF INTERDISCIPLINARY SCIENCE & TECHNOLOGY Thiruvananthapuram 42 42 structures, accompaniedby ahyperchromiceffect.( micellar extended 1D to finally and spherical self-assembly,0D hierarchical to the initially on impact significant a had dye the of structure the in variation subtle that demonstrated was It architectures. artificial light-harvestingassemblies( of design the in interests research further up open to expected are results These migration. exciton self-assembledfast andefficient (OPV) as aresultof donor molecular wires the structuretothe from in an organo gel medium. Energy transfer is feasible only in the case of the gel and occurs exclusively have been reported as acceptors, this is the first use of a molecular wire for trapping excitation energy chromophores and dyes organic of variety a Although antenna. harvesting light supramolecular a in wire, PYPV within the pi-gels facilitate fast exciton funnelling and efficient energy transfer which results with tunableopticalproperties( materials, which could open the window to a novel class of electronically active soft organic materials for the design of supramolecular light- harvesting assemblies and are potential two-photon-absorbing molecules showninthestructure,whichformgelsorganicsolvents.Theseareidealscaffolds ain otold h sl-seby f tioa surie y t shrcl n helical and spherical to dye squaraine tripodal a of self-assembly the controlled Cation Subsequently, it was demonstrated that the encapsulation of less than 2 mol% of a molecular Adv. Mater. Angew. Chem.,Int.Ed. 2007 ,19, 411) Chem. Commun, Chemical Science&Technology 2007 , 46 2008 , 6260) , 969). ANNUAL REPORT 2007-2008 , 43 43 for 1a in a solid a in ions was 1a 2+ -CD included β Chem. Commun. Chem. solution resulted in a 2+ fluorescence of a chiral ligand chiral a of fluorescence the fabrication of a reusable dipstick which is sensitive to Zn explored. A fluorescence “dipstick” coating by fabricated was support which upon dipping in an aqueous Zn change of fluorescence and color bright to greenish-yellow initial from Chemical Science & Technology Science & Chemical -CD-appended donor and a β and its use in the fabrication of the reusable the of fabrication the in use its and 1a ions were recently published ( published recently were ions 2+ -CD based supramolecular dyads -CD based supramolecular pp. 5173-85). β in biological as well as analytical samples are of paramount ,13, 2+ 2007 Photoinduced electron transfer (PET) between a Detection and imaging of Zn , 2903 - 05) Chemistry - A European Journal acceptor was studied in aqueous solution using fluorescence quenching and laser flash photolysis techniques. At very low the concentrations equilibrium of was acceptor, in favour of free molecules, and under these conditions fluorescence quenching was negligible and diffusion mediated electron transfer involving the triplet excited state of the donor predominated. At high concentrations of the acceptor the equilibrium was largely in favour of the supramolecular dyad and intra-ensemble calculated PET those with well very agree rates PET determined experimentally The predominate. processes ms 200 than more for survived pairs ion the of fraction a that observed was It equation. Marcus using ( Photoinduced Photoinduced electron transfer in Molecular Probes for the Detection of Zinc Ions under Aqueous Conditions interest due to the role of this cation in physiological functions. In this work, the high solid-state of properties optical synthesis, the of details The red. Zn of detection the for device fluorescence dip-stick 2008 NATIONAL INSTITUTE OF INTERDISCIPLINARY SCIENCE & TECHNOLOGY Thiruvananthapuram 44 44 2008 cations in these reactions was confirmed by esr and absorption spectroscopic studies ( derivatives and yields in excess of 80% were obtained in most cases. Involvement of the amine radical tetraphenylbenzidines. Synthetic utility of this reaction was yield demonstrated using to several triphenylamine reactions dimerization undergo which cations, radical amine give to acetonitrile imerization their and Cations Radical Triarylamine of Generation Mediated Cu(II) nanosecond timescaleswasthusenabled( the in states separated charge the of Observation slower. times 100 about were systems these rates the bipyridylruthenium dyads were studied. Very facile electron transfer takes place in these systems with donor-acceptorsystems photoinduced charge separationLong-lived new in , 9, It was earlier shown that Triphenylamine derivatives undergo electron transfer to Cu2+ in Cu2+ to transfer electron undergo derivatives Triphenylamine that shown earlier was It tris- substituted phenothiazine three of properties photophysical and Synthesis pp. 2709-12). k et > 10 8 s -1 . Compared to previously reported systems the back electron transfer rates in rates transfer electron back the systems reported previously to Compared . Photochem. Photobiol.Sci. Chemical Science&Technology 2008 , 7 , 826–33). Organic Letters ANNUAL REPORT 2007-2008 45 45 Chem. Chemical Science & Technology Science & Chemical , 6549-56). 111 , 2007 J. Phys. Chem. B , 5944-51). 13 , Novel cholesterol-appended squaraine dye which forms two H-type supramolecular assemblies supramolecular H-type two forms which dye squaraine cholesterol-appended Novel The single strand DNA (ssDNA) forms an important intermediate in processes such as DNA 2007 . Eur. J Eur. brought about by changing either the concentration, temperature or the solvent composition ( composition solvent the or temperature concentration, the either changing by about brought with opposite chirality was designed. the Interestingly, chirality inversion in these assemblies can be Supramolecular assemblies that Supramolecular undergo inversion chirality ssDNA in buffer ( changes in the fluorescence intensity. These systems can be used as probes for the quantification of which showed high water solubility and ability to distinguish between ssDNA and dsDNA through replication, recombination and repair. In this context, a few novel acridinium derivatives were synthesized were derivatives acridinium novel few a context, this In repair. and recombination replication, Design of novel acridinium derivatives and study of their interactions with ssDNA NATIONAL INSTITUTE OF INTERDISCIPLINARY SCIENCE & TECHNOLOGY Thiruvananthapuram 46 46 as sensitizersforphotodynamic therapeuticapplications( utilized for the development of potential sensors for the detection of metal ions and can be exploited favorably be can dyes absorbing infrared These ions. metal divalent the with interactions selective based croconaine dyes were synthesized. These dyes exhibited absorption 750-850 nm and underwent properties dyes:binding croconainemetalInfrared ion absorbing and synthesis 111 enhanced electron transfer reaction between the donor and acceptor moieties ( the in resulting dyads un-encapsulated the to compared as planarization unusual underwent group spacer aryl rigid with dyads the whereas structure, of type sandwich of unfolding conformational β -Cy -Cy -Cy -Cy -Cy , 11940-47). clo clo clo clo clo With the objective of developing near infrared (NIR) absorbing dyes, a few novel quinaldine novel few a dyes, absorbing (NIR) infrared near developing of objective the With in group spacer aliphatic having dyads the of Encapsulation de de de de de xt xt xt xt xt r r r r r in induced unusual p unusual induced p in unusual induced in in induced unusual p unusual induced in in induced unusual p unusual induced p in unusual induced in lanar lanar lanar lanar lanar iz iz iz iz iz at at at at at ion in e in ion e in ion ion in e in ion ion in e in ion e in ion J. Org.Chem Chemical Science&Technology lect lect lect lect lect β r r r r r –cyclodextrin ( –cyclodextrin on-donor a on-donor a on-donor on-donor a on-donor on-donor a on-donor a on-donor . 2008 , J. Phys. Chem. B 73 , 274-79). ccept ccept ccept ccept ccept β –CD) led to the to led –CD) or dya or dya or or dya or or dya or dya or 2007 ds ds ds ds ds , ANNUAL REPORT 2007-2008 47 47 ials Chem. lecular •Mater lecular ) interaction, which was further supported further was which interaction, ~ 865 nm). The excitons formed upon π Chemical Science & Technology Science & Chemical ··· max 14933-36. 111, 2007, J. Phys. Chem. C, , 265-72). 20 , A model phenyleneethynylene, which does not possess any functional groups, self-organizes Excited state properties of the croconate dyes were investigated with an aim to utilize them as them utilize to aim an with investigated were dyes croconate the of properties state Excited 2008 by theoretical calculations.( into wire-like structures on 2D surfaces. High-resolution STM imaging revealed that the molecules are molecules the that revealed imaging STM High-resolution surfaces. 2D on structures wire-like into of types two of existence the indicated domains various of Analysis fashion. 1D skewed a in arranged CH alkyl of modes different from arising packing molecular Self-Organization of Phenyleneethynylene into Wire-Like Mo Wire-Like into Phenyleneethynylene of Self-Organization excitation of the dye aggregates underwent charge separation at the TiO2 and SnO2 interface. ( interface. SnO2 and TiO2 the at separation charge underwent aggregates dye the of excitation Mater. light harvesting assemblies in the infrared (IR) region (l Harvesting dyes with photons croconate infrared on Surfaces NATIONAL INSTITUTE OF INTERDISCIPLINARY SCIENCE & TECHNOLOGY Thiruvananthapuram 48 48 ( nanoparticles the of size the on dependent was which nanorods Au of band Plasmon longitudinal the in shift bathochromic spontaneous a in resulted binding Site-specific binding. selective their to at theedgesofAunanorodspreferentiallyattracted thepositivelychargedAunanoparticles,leading nanoparticles was reported by exploiting the electrostatic attractive interactions. The enhanced potential Interactions Electrostatic through Nanorods Au of Functionalization End Preferential transfer fromthechromophoretogoldnanorod( energy efficient an indicated analysis decay Emission investigated. were properties state excited and Excited-Stateand InteractionsChanges Morphological Nanorods. Gold Functionalized Trisbipyridine Ruthenium(II) J. Am.Chem.Soc. nvl ehdlg fr h peeeta ed ucinlzto o A nnrd with nanorods Au of functionalization end preferential the for methodology novel A The tris-bipyridylruthenium chromophores were linked to gold nanorods and their photophysical 2007 , 129 , 6712-13). J. Phys.Chem.B., Chemical Science&Technology 2007 , 111 , 6839-44). ANNUAL REPORT 2007-2008 49 49 Chemical Science & Technology Science & Chemical Adv. Mater. In press). Mater. Adv. -tetraarylporphycene as shown here was demonstrated. The photophysical meso Syntheses, spectral and structural characterization of various Calixpyrrole, calixphyrin and The coupled Plasmon absorption of Au nanorod dimers was investigated as a function of properties showed, ten fold absorption (blue) in the Q-band region and two fold emission (red), higher (red), emission fold two and region Q-band the in (blue) absorption fold ten showed, properties Materials for applications sensors and therapeutic porphyrin isomer derivatives are reported. The pyrrole units in the ferrocenyl based calix[2]pyrrole showed 1,2-alternative conformation, which resembled the parent calix[4]pyrrole units. The positive binding. moderate the suggests anions various of addition the upon studies electrochemical the in shift The structural analysis of 1:1 calix[2]phyrin showed the synthesized self-assembled dimer, while is unit, the porphyrin 2:2 of isomer isomer structural a porphycene, hand, other the On array. 1D in exhibited methodology synthetic alternative the is which reaction, coupling oxidative acid-catalyzed the through time, first the For date. till route synthetic known only the is and reaction, coupling McMurray the for the synthesis of orientation between the long axes of the nanorod by linking them with rigid and flexible molecules. As molecules. flexible and rigid with them linking by nanorod the of axes long the between orientation wavelength longer to shifts band Plasmon coupled the increases, nanorods Au the between angle the overlap ( confirming the role of effective dipolar Plasmon Coupling in Dimers of Au Nanorods NATIONAL INSTITUTE OF INTERDISCIPLINARY SCIENCE & TECHNOLOGY Thiruvananthapuram 50 50 An attemptwasmadetorelatethestructurewithfunction( optical response ( conjugated have which (Figure) porphyrins Expanded and Porphyrins on based are materials These characterized. and synthesized been have response Materials Non-LinearOptical Organic Generation New Photodynamic therapeutic(PDT)applications.(Org.Lett.2007,9,4769-72.) than the respective parent porphyrin unit, which clearly suggests that this is a potential candidate for A newsetofnon-linearopticalmaterialswhichshowveryhighthirdorder J. Phys. Chem. B 2008 , 112 , 6900-05), they also exhibit a variety of structural diversity. π -electrons. In addition to excellent non-linear excellent to addition In -electrons. Chemical Science&Technology Acc. Chem.Res. 2008 , 41 , 265-79). ANNUAL REPORT 2007-2008 51 51 Tetrahedron Tetrahedron Lett., ,46,6277-88) 2007 components in cycloaddition in components π or 2 or π Inorg. Chem. Chemical Science & Technology Science & Chemical selective ON-OFF type fluoroionophoric properties fluoroionophoric type ON-OFF selective 2+ (spirodienone) derivative of calix[4]arene with nitrones that provided ions encapsulated in a single platform was demonstrated by UV-vis, 2+ bis . thiacalix[4]arene derivative bearing four 8-quinolinoloxy groups through flexible Calix[4]bis(spirodienones) can perform as either 4 either as perform can Calix[4]bis(spirodienones) - Selective FluorescentThiacalix[4] Sensor Based on 1,3-Alternate H NMR and MALDI-TOF mass spectral studies ( H NMR and MALDI-TOF 1 2+ A new thiacalix[4]arene derivative 2 bearing four quinolinoloxy groups through propyl chains propyl through groups quinolinoloxy four bearing 2 derivative thiacalix[4]arene new A ,49,1750-52) The unusual formation of a tetramercury complex and mercury selectivity of a newly synthesized 1,3-alternate The unusual formation of a tetramercury complex and mercury selectivity of a newly arene Anchored with Four 8-Quinolinoloxyarene Anchored Groupswith Four 2008 Novel 1,3-Dipolar Cycloaddition 1,3-Dipolar Novel reactions of calix[4]bis(spirodienones): Synthesis of Isoxazolidine derived derivedmacrocycles macrocycles cycloaddition reactions of a formation of highly functionalized macrocycles. Highly regio- and stereoselective 1,3-dipolar derivatives could be conidered as direct precursors of 1,3-amino alcohols ( reactions with various carbo- and hetero-dienophiles and with 1,2-benzoquinones leading to the isoxazolidine These demonstrated. was yields excellent in macrocycles derived isoxazolidine to access easy complex 3 involving four Hg among the representative transition- and heavy metal ions. The unusual formation of a tetramercury fluorescence, investigated. The receptor exhibited pronounced Hg pronounced exhibited receptor The investigated. in 1,3-alternate conformation was synthesized and its metal ion binding and sensing properties were properties sensing and binding ion metal its and synthesized was conformation 1,3-alternate in A New Hg A New 2. ORGANIC CHEMISTRY 2. ORGANIC NATIONAL INSTITUTE OF INTERDISCIPLINARY SCIENCE & TECHNOLOGY Thiruvananthapuram 52 52 study is schematically shown below ( entire The compounds. functionalized highly gave oxidation mediated CAN and cyclization Reductive cycloaddition reaction of azomethine ylides (AMY) and 3-spirolactone oxindoles using Indium chemistry. 1,3-dipolar using oxindoles heterocyclic dispiro and mono- important pharmacologically various of construction the for utilized were heteroaldehydes and isatin from derived adducts MBH the Hence, MBH-adducts from isatin which has not been utilized for the synthesis of novel 3–spiro oxindole synthesis. synthesis for the construction of complex molecular architectures. Garden organic to latitude bringing in role important an play which molecules functionalized densely giving of coupling the involves and bond Novel Synthetic Methodologies Based on Morita-Baylis-Hillman (MBH) adducts The MBH reaction has become a powerful tool for the atom economical construction a C-C a construction economical atom the for tool powerful a become has reaction MBH The ‘Novel reactivityofbisspirodienoneshowingdipolarophilicbehaviour’ Novel SyntheticTransformations ofMBHadducts ofIsatin α Org. lett, -position of activated alkenes with an electrophile under DABCO under electrophile an with alkenes activated of -position 2007 , 9, 4095-98. Chemical Science&Technology Tetrahedron Lett, et al reported the synthesis of 2008 , 49, 2611-15) . ANNUAL REPORT 2007-2008 53 53 . A silicachloride A . , 60, 850-56) 2007 Chemical Science & Technology Science & Chemical combined with their structural architecture and impressive and architecture structural their with combined The development of novel and efficient methodologies for , 48, 9190-94. Aust. J. Chem., , 48, 9190-94. Aust. 2007 range of biological activities sustains unabated interest in the synthesis of eleven membered carbocycles. A novel and versatile was carbocycles membered eleven of synthesis the towards method unraveled through a three step reaction sequence from pentafulvenes. The [6+3] adduct of pentafulvenes with 3- ruthenium by followed reduction selective on betaine oxidopyrylium catalyzed oxidative cleavage afforded a novel eleven membered methodology The linkage. ether bridging a with triketone carbocyclic the synthesis of eleven membered carbocycles is an interesting challenge in synthetic organic chemistry. Natural products based and important the of one constitute skeletons membered eleven on largest groups among diterpenes. The broad distribution of these molecules Tetrahedron Lett, Tetrahedron Clavularia Koellikeri’ A facile and efficient stereoselective synthesis of highly functionalised trisubstituted alkene isolated from the soft coral ‘Neodolabellane is a diterpenoid A Simple and Eff icient Strategy towards Eleven Membered Carbocycles via Novel via Carbocycles Membered EffEleven and towards StrategySimple icient A Transformations Syntheticof Pentafulvenes derivatives of ferrocenealdehyde was achieved from MBH adduct of ferrocenealdehyde of adduct MBH from achieved was ferrocenealdehyde of derivatives were developed ( catalysed one-pot isomerisation-chlorination, arylation and etherification of Baylis-Hillman adducts NATIONAL INSTITUTE OF INTERDISCIPLINARY SCIENCE & TECHNOLOGY Thiruvananthapuram 54 54 asymmetric synthonsofhighvalueinalimitednumber ofsteps. result in low or moderate yields. Desymmetrization of meso compounds provides an efficient route to usually and steps several involve syntheses reported the of most and cyclopentenes 3,4-disubstituted complex structures from simple precursors. There are no general methods available for the synthesis of of stereoselective carbon-carbon coupling reactions providing a broadly applicable method to synthesize Intermediates Pharmaceutical towards ins olef Mesobicyclic of Desymmetrization Catalyzed Palladium 35, 5847-51). materials starting available easily and cheap from efficiency atom of level high with proceeds and system catalytic elaborated an requires hardly it as noteworthy is procedure described herein is easy to perform and delivers densely functionalized carbocycles in good yields. The One of the most important goals in contemporary synthetic organic chemistry is the development Biologically activesubstitutedcyclopentanes Chemical Science&Technology (Eur. J. Org. Chem., (Eur.Org. J. 2008 , ANNUAL REPORT 2007-2008 55 55 Oryza sativa Oryza and , vicinal disubstituted vicinal , trans . , 5, 4010-19) Chemical Science & Technology Science & Chemical 2007 (Org. Biomol. Chem., (Org. Biomol. Chem., Biologically active compounds isolated from Curcuma amada Curcuma amada plant inflorescence rhizome In the natural products program, the institute is involved in harnessing the natural wealth A mild and general methodology for the stereoselective synthesis of synthesis stereoselective the for methodology general and mild A Alpinia calacarata, Kaempferia rotunda, Curcuma amada, Curcuma malabarica Curcuma amada, Curcuma rotunda, Kaempferia calacarata, Alpinia medicinal variety called ‘njavara’. Several biologically active compounds have already been isolated and characterized from these plants. (plant/herbal) of the region to obtain novel biologically active compounds or leads for drug synthesis. drug for leads or compounds active biologically novel obtain to region the of (plant/herbal) Specific attention is given to the discovery of antioxidants, anti-inflammatory agents and anticancer compounds from well known medicinal plants used in Ayurveda and Sidha. Plants chosen for study include Natural ProductNatural isolation and biological Screening cyclopentanes was developed through palladium/Lewis acid mediated ring opening with the formation the with opening ring mediated acid palladium/Lewis through developed was cyclopentanes bond of a new carbon-carbon NATIONAL INSTITUTE OF INTERDISCIPLINARY SCIENCE & TECHNOLOGY Thiruvananthapuram 56 56 digestion. Following chemicalconstituentswereisolated Malabarica Curcuma from constituents chemical of Isolation fractionation of the different extracts of the Njavara samples is guided’ progressing ‘Activity-using different samples. procedures. rice non-medicinal ordinary, of extracts similar to compared effects scavenging radical antioxidant, in effective four-foldmore nearly were fractions) rice and bran (both HPLC,methods wereusedtoisolateandidentifythebioactivecompoundsinit. mg/100g. 8.20 ± 1570 was bran rice of that and ±1.71) (39.0 was extract rice Njavara of content different by evaluated as variety ordinaty to activity,compared antioxidant higher significantly have samples “Njavara” that showed samples the of extracts solvent by Kerala State Science, Technology & Environment (KSCSTE) last year. Studies carried out with different The EC50 values based on different radical scavenging studies also showed that Njavara samples A project on ‘Chemical prospecting and This plant is traditionally used for the treatment of stomach ache and enhancement of ‘Curcuma malabaricaplantshowing Leaf, inflorescence& rhizome’ in vitro antioxidant bio activity of Njavara’ was sponsored (Mol. Carcinogenesis, Chemical Science&Technology in vitro in methods. The total phenolic total The methods. 2007 , 46,231-41). ANNUAL REPORT 2007-2008 57 57 rs rs rs rs rs e e e e e at at at at at al w al w al w al w al w ur ur ur ur ur Chemical Science & Technology Science & Chemical ed nat ed nat ed nat ed nat ed nat aminat aminat aminat aminat aminat han cont han cont han cont han cont han cont Endosulp Endosulp Endosulp Endosulp Endosulp ion of ion of ion of ion of ion of at at at at at ic ic ic ic ic MIP micro beads utilizing Dummy Template concept (Chlorendic acid) suitable for detoxification for suitable acid) (Chlorendic concept Template Dummy utilizing beads micro MIP Imprinted polymers based drug delivery system (DDS) was developed for metal - based drug: xif xif xif xif xif o o o o o et et et et et D D aniline and acryl amide as functional monomers and 1, 1,1-tris(hydroxy methyl) propan-trimethacrylate methyl) 1,1-tris(hydroxy 1, and monomers functional as amide acryl and aniline of endosulfan contaminated natural waters prepared. The micro beads were prepared using 4-Vinyl D copper salicylate (an non-steroidal anti-inflammatory drug). The schematic representation of DDS is given below. development of such Metal based Metal drug delivery 3. INORGANIC & POLYMER MATERIALS & POLYMER 3. INORGANIC D D NATIONAL INSTITUTE OF INTERDISCIPLINARY SCIENCE & TECHNOLOGY Thiruvananthapuram 58 58 of the unpaired 4f electron of the praseodymium ion. The an additional electronic energy level in the forbidden band The colour of the pigments arises from the introduction of synthesized having colours ranging from white to brick red. by doping praseodymium into CeO colorant earth rare brown-red benign Environmentally 2007 molecular device in many photonic applications. ( that the xanthene-9-carboxylic acid complex of Tb ms), whereas the luminescence of Eu Tb the of sensitization energy transfer. The triplet state of the ligand was located at ~ 25839 cm antennae effect with respect to the Tb Terbium-device molecular conversion light Xanthene-9-carboxylateas organic and inorganic pollutants(POP’s & PIP’s), actual chemical warfare agents(CWA’s) and radionucleides. WHO i.e. 20 ppb. This concept will be a forerunner for detoxification of other deadly toxins like persistent by stipulated level permissible maximum the below much levels to down waters natural contaminated in present endosulphan removed beads MIP washed methanol The monomer. linking cross the as , 10,393;Inorg.Chem.Commun. Novel environmentally secure inorganic pigments inorganic secure environmentally Novel Luminescence studies demonstrated that the xanthene-9-carboxylate ligand exhibited a good 3+ -centered luminescence (quantum yield 7.30 ( 0.73%; lifetime 1.11 ± 0.01 ± 1.11 lifetime 0.73%; ( 7.30 yield (quantum luminescence -centered 2 matrix of TiCeO 3+ was only poorly sensitized. Thus, the present results demonstrate 3+ ion due to efficient intersystem crossing and ligand-to-metal 2007 , 10,1091 Inorg. Chem. 3+ may find potential applications as a light conversion 4 were ) Chemical Science&Technology 2007 , 46, 11025; Inorg. Chem. Commun. -1 , which resulted in a sizable ANNUAL REPORT 2007-2008 59 59 J. Phys. , 3591-600.; 111 , 2007 . , 77, 427) Chemical Science & Technology Science & Chemical 2008 J. Phys. Chem. C ; Dyes and Pigments Dyes and Pigments 40, 7311-19. . This immobilized enzyme is useful for the synthesis of peptides in , -1 g 2 2007 , 12772–80) 111 , Macromolecules, 2007 The protease, Subtilisin was encapsulated in sol gel matrices using alkoxysilane precursors of A renewable resource based amphiphilic surfactant was designed and developed for soft Among the different clays and organisms tried, the china clay from Orissa containing iron in silane) was found to be 38 m of 5-20 microns. The specific surface area of the immobilized subtilisin in VTMS (Vinyl tri methoxy cycles of repeat use. The SEM micrograph of the immobilized enzyme showed uniform round particles round uniform showed enzyme immobilized the of micrograph SEM The use. repeat of cycles temperature of 60°C. The biocatalyst sol gel particles retained 50% of the original activity even after 11 after even activity original the of 50% retained particles gel sol biocatalyst The 60°C. of temperature glass enzyme had the same optimum pH of 7.0, but the optimum temperature was shifted to a higher a to shifted was temperature optimum the but 7.0, of pH optimum same the had enzyme glass different chain lengths. The entrapment efficiency of the sol-gel glass was about 80%. The resultant Protease immobilized in sol-gel matrix, stability and catalytic activity in xerogels in activity catalytic and stability matrix, sol-gel in immobilized Protease sensing. ( hydroxyl functional groups at the nano-surface to trace the molecular interactions through vitamin-C through interactions molecular the trace to nano-surface the at groups functional hydroxyl Tailor made Tailor synthetic methodologies were also developed for nano-spheres bearing mono and bis- Conducting polymer nano-materials nano-tubes. and nano-spheres nano-rods, nano-fibers, as such nano-materials polyaniline templating iron content. pyrite form responded well to leaching with certain fungi giving improved brightness and reduction in reduction and brightness improved giving fungi certain with leaching to well responded form pyrite various surface coating applications ( various surface coating removalMicrobial mediated of from kaolin foriron minerals value addition brown red ceramic pigments were found to be interesting alternative to existing toxic pigments for Chem. B. NATIONAL INSTITUTE OF INTERDISCIPLINARY SCIENCE & TECHNOLOGY Thiruvananthapuram 60 60 DTA ,DSCandrheologystudies.APCTpatentwasfiled. thermally more stable and gave a strong gel as were compared to chitosan gels and xyloglucan composite as shown by The TG- chitosan. to bonded covalently was xyloglucan dialdehyde when formed the with residues glucopyranosyl of position applications novel composite Xyloglucan gelsfor applications. improved bioavailability and bioactivity useful for pharmaceutical, medical, cosmetic and other industrial for polymers biodegradable of particles nano/micro in encapsulated were molecules these of Some benefits. health pronounced as well as property colouring have lycopene and lutein carotene, beta care. Many natural colours including anthraquinones, diferuloyl methane, dihydroxy 1,6 benzo quinones, carriers for therapeutic compounds to target cells and tissues for effective medicinal usage for health advent of nanotechnology, wherein biocompatible nanoparticles have been developed as inert systemic particles chitosan in nano/micro biomolecules of Entrapment FT-IR analysis.( ionic liquid. The formation of dipeptides and tripeptides of L-alanine was confirmed by TLC, HPLC and Xyloglucan has a the with revolutionized been has delivery drug of field the decade, past the of course the In (J.AppliedPolymerSci., Applied Catalysis β (1-4) linked D – glucan back bone that is partially substituted at the O-6 2008 2008 , 341,168) , 2899-908) α –D –xylopyranose. A transparent, colourless gel was gel colourless transparent, A –xylopyranose. –D Chemical Science&Technology ANNUAL REPORT 2007-2008 61 61 . 65 kg. This has a climbing speed of S/cm at 750°C useful for fuel cell "4 -10 -3 MATERIALS AND MINERALS DIVISION AND MINERALS MATERIALS ves ves ves ves ves i i i i i fabrication. Superconducting current leads having ratings upto 1000A at 77 K and 2000A at 64 at 2000A and K 77 at 1000A upto ratings having leads current Superconducting fabrication. (DAE) for use. Indore K were developed and delivered to RRCAT modified suitably was NIIST at developed rutile synthetic of production for process eco-friendly The estimated an with plant pilot a setup to limited Rutile and Minerals Cochin M/s to transferred and cost of Rs.100 crores. This is one of the biggest technology transfers of CSIR. natural on based counterparts commercial than higher strengths with adhesives sensitive Pressure rubber and PCNSL developed. polychloroprene rubber, A Coconut Climbing Bike developed with a lift capacity of 6m/min. and a descending speed of 3.8m/min. A new ultra low temperature (650°C) sinterable LTCC material developed which had permittivity had which developed material LTCC sinterable (650°C) temperature low ultra new A of 17 with low loss tangent of 0.006 at 7GHz. Perovskite oxides prepared by the solid state reaction technique indicated that they are ionic conductors with conductivities of the order of 10 Successful road testing of Al-SiC functionally graded brake rotor disc in a multi utility vehicle for vehicle utility multi a in disc rotor brake graded functionally Al-SiC of testing road Successful automotive applications. Structural integrity of the disc was very good cast iron disc. efficiency compared to conventional with closer braking composites SiC 10% Al(356)- to alloy Al(356) of joint material dissimilar of welding stir Friction for structural engineering applications. casting stir metal liquid by composites matrix aluminium reinforced carbide boron of Synthesis techniques for nuclear shielding applications. Synthesis of in-situ formed nano-crystalline aluminium nitride reinforced aluminium matrix composites for electronic packaging applications. reduction size pore the where BHEL at tested successfully setup membrane ceramic all prototype A NIIST from 1500 nm to <200nm was achieved by the technique developed in Basic and applied research on advanced ceramics for structural and functional applications. research on advanced ceramics for structural Basic and applied well as catalysts coatings/membranes, particles, nano for precursors ceramic of synthesis Sol-gel as ceramic fabrication. ceramics and ceramics electronic superconductivity, Tc high of area the in work Developmental for communication. mineral and resources material non-renewable and renewable of addition value and Exploitation based technologies. materials graded functionally and composites matrix metal their alloys, light new of Development for strategic as well as societal needs. of materials using EM Microstructure and microchemical analysis Materials for societal applications Object Object Highlights Object Object Object NATIONAL INSTITUTE OF INTERDISCIPLINARY SCIENCE & TECHNOLOGY Thiruvananthapuram 62 62 coating onmetalbyPlasma-spray methodatthecollaborator’slaboratory(BARC, Mumbai). for used was composite the of micrograph.150gms TEM the in observed were nm 50 ~ size of particles sintering the composite precursor at 1000 after even nm ~270 only to limited was composites phosphate-yttria lanthanum of growth grain The TGA. and IR XRD, by characterised completely was product dried The route. sol-gel through investigated phosphatesinteredand ceramics coatingsand earth rare nanosize with metals molten of behaviour wetting and Reactivity composites forthermalbarriercoatingsweredevelopedatlaboratorylevelfurtherscaleup. for further calculations for pilot plant at IRERC. Development of Rare earth phosphate nano phosphors and conditions along with the material balance (including the amount of solvent use and recovery) were estimated processing the of details The nm. 300 > bulk of that and nm 100 < was colloids phosphate lanthanum nanosized of size particle Average stability. phase and size particle for characterized fully was capacity phosphate (lanthanum phosphate) at IRE, Kollam, the lanthanum phosphate synthesized in the lab at 1 Kg Kollom PhosphatePilot Earth plant for nano Rare •at M/s Limited,Earths Indian Rare 1.1.Programme Nanomaterials 1. CERAMICMATERIALS DEVELOPMENT ytei prmtr o Yti-atau popae ao atclts 1010 m were nm) (100-150 particulates nano phosphate Yttria-Lanthanum of parameters Synthetic earth rare Kg 10-15 of synthesis the for facility a creating for project sponsored IRE the Under Room temperaturephotoluminescenceinEuropiumdopedlanthanumphosphategel o C. Spherical polyhedra as well as extended polyhedral (rod-like) Materials andMinerals ANNUAL REPORT 2007-2008 63 63 C o al-Mechanical- at 1000 3 O 2 Materials and Minerals Materials :20%Y 4 ions •as Chemic nanospheres of average size 7.4 nm displaying three prominent lattice fringes. The inset is the nanospheres of average size 7.4 nm displaying three prominent lattice fringes. The 2 and particle size distribution of LaPO TEM Micrograph PDI of 0.20) synthesised through precipitation in mixed solvent using steric stabiliser. Nanosized cerium oxide (4-8 nm) was reproducibly synthesised by wet chemical methods with a HR-TEM image of CeO HR-TEM FFT data of 6.5 nm monodispersed suspension (indicated by low analysis of the image and photon correlation spectral control over the kinetics of the reaction. HR-TEM, X-ray diffraction and BET Surface area were used to understand complex relation among particle fringes’ lattice size of type and ‘one the related from evident crystal as crystals properties single were particles e.g., small The lattice parameter, anisotropy. and strain in one particle as shown in the TEM image fine below. monodisperse Particle such one growth for data and scattering light The polydispersity syntheses. the were in surfactant completely employing by avoided crystals is shown in the PCS pattern. Cerium oxide based Nanomaterials for Applicat Polishing (CMP) Polishing Slurry. NATIONAL INSTITUTE OF INTERDISCIPLINARY SCIENCE & TECHNOLOGY Thiruvananthapuram 64 64 progress aspartofcommercialisation. in are tubes mm 1000 containing modules larger of fabrication and filtration water industrial for tested Modules containing 25 number of 19 channel coated tubes of 500nm length were fabricated at BHEL and flow rate and amount water filtered through the tubes under the different hydraulic pressures were evaluated. The tubes. all for ~50m was size pore and 4-5µm of thickness a to titania and boehmite of nanocolloids aqueous with coated further were ~300-500nm.They of dia pore and ~20µm of thickness having the laboratory experiments. The porous substrates were coated in with an initial layer (precoat) of alumina slurry ~50nm to down brought were which 1.4µm diameter pore average have tubes supplied BHEL channel 200 and 500 mm long sintered porous alumina tubes for water filtration is in the final stage. The ceramicmembranes iltration f Ultra composite varistorsshowedenhancedbreakdownvoltagefromthebasicvalueofB and studied been have characteristics voltage vs. Current achieved. were microns 5 as low as size grain average and microstructure grained fine showed varistors composite The conditions. laboratory under were mixed up to 10 by conventional sintering (1150 deg) and step sintering (850 deg). Chemically derived varistors powders decomposition behaviour, and particle size were characterised. Dry pressed varistors discs were sintered thermal characteristics, morphology,sintering powder The route. reflux by followed precipitation co precursors nano varistorsthrough ield f energy High h Poet o dvlpn tcnqe o apyn gain crmc ebae otn o 19 on coating membrane ceramic gradient applying of techniques developing for Project The ZnO varistor with Bi SEM imageofcoated19channel poroustubeforfiltrationapplication(S)19channeled porous aluminaSubstrate(I)Intermediate layeralumina(T)Top titanialayer wt% with conventional spray dried varistors powder and varistors discs were fabricated 2 O 3 , CoO, Cr 2 O 3 , Sb 2 O 3 , Pr 2 O 6 and Y 2 O 3 dopants were synthesised through Materials andMinerals v =150-350V. ANNUAL REPORT 2007-2008 65 65 Materials and Minerals Materials photocatalyst was used probably for 2 is successfully prepared which are stable 2 with higher photocatalytic activity than the commercial 2 coated glazed floor tile at different calcinations temperatures. 2 added TiO 2 . Sol-gel derived nanocrystalline TiO 2 coatings were developed on fired terracotta bodies and sintered flux bonded flyash tiles. As tiles. flyash bonded flux sintered and bodies terracotta fired on developed were coatings High surface-area nanocrystalline TiO Algae growth and soiling of roofing and ceramic products is a cause of great concern in areas Similar Variation of degradation rate SiO of degradation rate Variation the first time as surface-sensitizer for the electroless copper-coating of flyash. the first time as surface-sensitizer for the electroless copper-coating Titania-based functionallyfor as ydrogen a graded photocatalyst nanocomposite production and other industrial applications Degussa-P25 was synthesized by modifying the conventional sol-gel process A using an organic polymer. new theoretical model was developed to explain the synergistic effect in the photocatalysis multiphase using nanocrystalline TiO the having moderate to high humidity as the aesthetics and colour of the tiles are affected. Commercial glazed Commercial affected. are tiles the of colour and aesthetics the as humidity high to moderate having titania Different technique. coating dip by sols titania doped and pure of layer thin a with coated were tiles based colloid compositions were developed using alumina and silica additions in the range 5-30%. The dried mixed colloids and the coated tiles were calcined at temperatures in the range characterised 600°-800°C for photoactivity. and Coating composition with SiO Antialgal, antibacterial and antisoilingAntialgal, coatings on traditional ceramics of 800°C. even up to a calcination temperature composition up to 10 litre volume was synthesised in the laboratory a part of scale up, titania sol of fixed and coatings were made in the collaborating industry. The coated tiles and ceramic products exhibited good self cleaning and ant algal properties. NATIONAL INSTITUTE OF INTERDISCIPLINARY SCIENCE & TECHNOLOGY Thiruvananthapuram 66 66 effect ofhydrolysiswateronthedensityandverylowas0.3m mesoporous. Thedensityobtainedforthehybridspreparedbyvaryinghydrolysisconditionsshow are they that indicating nature IV type below.the of were gels the for obtained isotherms adsorption The networking catalysed by an amine. The final dried gel with negligible shrinkage is provided in figure given incorporated been have ormosils 3-glycidoxypropyltrimethoxysilane The materials. storage gas as applications demonstrated. Due to the high density of organic functionality in these porous hybrids they may find successfully was systems hybrid inorganic organic to technique drying pressure ambient an of solution is a viable technique adopted for ambient pressure drying for these porous solids. The extension from catalysts to high energy particle collectors. Strengthening the gel network by aging in precursor Route drying subcritical through Aerogels Highly porous silica monoliths like aerogels find applications in a wide range of fields ranging into the tetraethoxysilane derived inorganic network through co-condensation and organic and co-condensation through network inorganic derived tetraethoxysilane the into Electroless copper-coating offlyashusingnanocrystallineTiO 2 as surface-sensitizer Materials andMinerals 2 g -1 couldbeachieved. ANNUAL REPORT 2007-2008 67 67 -2wt% chitosan -2wt% 2 Materials and Minerals Materials -2wt%chitosan (MTMS:TEOS = 2.5) 2 is a well known incipient ferroelectric incipient known well a is 3 hydrolysis-condensation reaction of in situ -2wt%chitosan(VTMS:TEOS = 2.5) and D) SiO -2wt%chitosan(VTMS:TEOS = 2.5) and D) 2 (n>8), were investigated in the temperature range 8 to 295K. The permittivity Stereomicrographs of water drops on glass slides A) Uncoated B) SiO Stereomicrographs of water drops on glass 15+3n O 5+n Displacive ferroelectrics contain a group of incipient ferroelectrics or low temperature A new organic-inorganic hybrid was synthesized through a sol-gel process starting from Ti 2 (MTMS:TEOS =1) C) SiO Ce -Chitosan sol showed ~100% optical transmittance in the visible light. -Chitosan sol showed ~100% optical 2 2+n material. The microwave dielectric properties of a group of novel incipient ferroelectric materials, Sr ferroelectrics having a variety of interesting properties and applications. The relative permittivity it value of maximum a reaching after and temperature in decrease a with increases ferroelectrics incipient SrTiO transition. ferroelectric a of absence the indicating saturates increases with decrease in temperature and saturates below 30K indicating the incipient ferroelectric minimum a reaching temperature, in decrease with decreased tangent loss dielectric The (figure). nature with further cooling. at about 80-120K depending on the composition, and again increased Materials for Newwireless Communication: incipient ferroelectric materials 1.2. Materials for1.2. Electronics and Communication Biocompatible silica-chitosan Biocompatible hybridssilica-chitosan and coatings hydrophobic alkoxysilane and chitosan and functionalized by the process The medium. reaction the in (VTMS) vinyltrimethoxysilane and (MTMS) methyltrimethoxysilane yielded highly transparent and hydrophobic silica-chitosan hybrids. The condensation of the hybrid functionalized with coated substrates Glass hydrophobicity. imparted particles silica-chitosan the over SiO NATIONAL INSTITUTE OF INTERDISCIPLINARY SCIENCE & TECHNOLOGY Thiruvananthapuram 68 68 ranges. Thestackedandsintered LTCC had apermittivityof17withlosstangent0.006at 7GHz. stacked and fired and the properties of the LTCC were measured in the radio and microwave frequency then were tapes The plasticizer. and binders ceramic the of slurry a from made were composite the material. Addition of a small amount of rutile improved the temperature stability of the LTCC. Tapes of temperature stableandhadlowpermittivitydielectric losstangent. were composites These material. electrode silver the with reactivity chemical no with (<950°C) 10% BaO-B material were developed. Fosterite (Mg modules withlowdielectriclossandembeddedsilverelectrodesetc. tapes called the low temperature cofired ceramic (LTCC) enable fabrication of three dimensional ceramic consumer electronic market. In the development of complex miniaturized circuits, flexible glass ceramic the in products microwave and systems communication wireless the of growth rapid the of because (LTCC)Ceramics ired Low TemperatureCof A new composite Zn LTCCloss low Several silver,with cofireable composites, ceramic-glass electrode common the attention much attracting are components electronic multifunctional and weight light Small 2 O 3 -ZnO-SiO 2 glass, and CeO Variation ofrelativepermittivityatcryogenictemperatures 2 Te 3 O 8 was developed as an ultralow temperature (650°C) sintereable LTCC 2 SiO 2 -BaTi 4 ) + 15 wt% Li 4 O 9 + 12% B 2 2 O-B O 3 -1% CuO had low sintering temperature 2 O 3 -SiO 2 Materials andMinerals glass, 0.83ZnAl 2 O 4 -0.17TiO 2 + ANNUAL REPORT 2007-2008 vcp" δ 69 69 " 20229 20228 20227 20226 20225 20224 20223 202257 202252 202247 202242 202237 202232 202227 composites 2 4 " " " 9"IJ| 3"OJ| Materials and Minerals Materials Xqnwog"htcevkqp"qh"EgQ 202203204205206207208 ceramic content in PTFE/ CeO 2 Variation of relative permittivity and loss Variation 8 7 6 5 4 3 2 9 8 7 6 5 4 3 2 ghh " hhgevkxg"tgncvkxg"rgtokvvkxkv{"* G tangent at 1 MHz and 7 GHz as a function of + ε CeO 16 O 5 Ti 2 -PTFE/polyethylene, SrCe -PTFE/polyethylene, 2 , CeO , 2 -TiO 4 O 2 Ceramic-polymer composites consisting of ceramic particles filled in a polymer matrix form a PTFE/ZnAl composites with desired properties can be synthesized. be can properties desired with composites given. figure in shown as range frequency microwave the in a judicious selection of filler ceramic and polymers, tangent loss low and 20 to 5 range the in permittivity interaction between the filler and the matrix. Thus with Thus matrix. the and filler the between interaction were prepared by hotpressing showed a very low properties of the phases, preparation method and the and method preparation phases, the of properties -polystyrene were prepared. The composites which phases, volume fraction of the filler, the individual various factors such as the number of components or coefficient of thermal expansion are dependent on viz. the dielectric constant, thermal conductivity and polymers. The key properties of the composite material composite the of properties key The polymers. flexibility, chemical stability and ease of processing of the electrical properties of ceramics and the mechanical the and ceramics of properties electrical the potential group of materials for producing demanding and functional packages, since they combine Ceramic-polymer composites for composites electronicCeramic-polymer packaging applications NATIONAL INSTITUTE OF INTERDISCIPLINARY SCIENCE & TECHNOLOGY Thiruvananthapuram 70 70 indicated that they were ionic conductors with conductivities of the order of 10 in air, wet oxygen and dry oxygen atmosphere grains. AC impedance spectral measurements sintered well showed (SEM) microscope morphology observation by scanning electron grain The Pm3m). (SG, structure type NaSrTiMO and Pnma) group, (Space structure type ZrMO NaCa & ray diffraction (XRD) showed that NaCaTiMO technique. Phase identification by powder X- reaction state solid the by prepared were reaction state solid value in intermediate temperature range, perovskite oxides were synthesized by use of the conventional many serious problems. In the course of searching a new material which exhibit equivalent conductivity which have got conductivity of 0.1 S.cm Ionic conductors type provskite (i) New applications electro-optical and electrical ceramic for oxidesfunctional Novel applications Optic Electro and 1.3.Electrical Materialsfor of thecompositeswerefoundtoincreasewithinterfacialarea. when theinterparticledistancereducedto~250nminbothcases.Thepermittivityandconductivity found was behaviour percolative The 50%. was powder coarse for value corresponding the while The method. gel citrate composites with fine powder by of LSCO showed a powder rapid increase in permittivity fine and conductivity at 30% as and reaction state solid by powder grained coarse as of polytetrafluoroethylene and different volume fractions of La on dielectric properties of insulator-conductor composites was demonstrated by studying composites near the percolation limit of the conducting phase. The influence of conducting phase characteristics composite materials permittivity Giant Yttria Stabilized Zirconia (YSZ) is one of the popular electrolytes in solid oxide fuel cell (SOFC) Composites with conducting phases dispersed in an insulating matrix exhibit high permittivity 6 & NaSrZrMO 6 had orthorhombic perovskite orthorhombic had . New oxides of the type, NaATiMO type, the of oxides New 6 had cubic perovskite -1 at 1000 6 o C. But high temperature operation of SOFC causes 6 and NaAZrMO and SEM MicrographofNaSrZrNbO 0.5 Sr 0.5 CoO Materials andMinerals 6 (A=Ca or Sr; M=Nb or Ta),or M=Nb Sr; or (A=Ca 3 (LSCO). LSCO was prepared -3 -10 "4 S/cm at 750 °C. 6 ANNUAL REPORT 2007-2008 , 71 71 12 O 3 , but the 4 by structural by 4+ 28 . The intense red 7 O 2 Nb 7 Ti 4 Ce 3 Ca Materials and Minerals Materials (b) 28 was of the order of 10 4 O 3 Nb 6 Ti 3 Ce 4 levels. For both silicate phosphates, full red colour red full phosphates, silicate both For levels. 3+ transitions in Eu in transitions 0, 1, 2, 3, 4 3, 2, 1, 0, F 7 to , which remains in the reduced state without being oxidized to Ce to oxidized being without state reduced the in remains which , 0 D 3+ 5 Typical scanning electron micrographs of (a)Ca Typical prepared and characterized by XRD earlier, were studied from their Emission Spectra. The Spectra. Emission their from studied were earlier, XRD by characterized and prepared 12 The luminescent properties of new phosphor materials based silicate phosphates SrYSiP Semiconducting oxides find several applications as thermistors, PTCR materials, sensors, O 3 for good and stable structure. emission was observed with high intensity. Work is in progress to optimize the calcination temperature calcination the optimize to progress in is Work intensity. high with observed was emission samples were excited at 393 nm. The Emission intensity of YPO (iii) New phosphor Materials for white light emitting for Materials (WLEDs) diodes white (iii) New phosphor that these oxides belong to cubic pyrochlore crystal system in the space group Fd3m (No.227). that these oxides belong to cubic pyrochlore to corresponding stabilization. The structure refinement of X-ray powder diffraction data using Reitveld analysis established analysis Reitveld using data diffraction powder X-ray of refinement structure The stabilization. CaYSiP silicate phosphate samples showed much enhanced intensity, of the order of 10 emissions (554-559, 593, 613-620, 650-661, and 695-703nm) were observed for the sample the presence of Ce of presence the Arrhenius equation for The conductivity. electrical conductivity in this compound is probably due to The activation energy of the carriers was found to be in the range of 0.4eV to 1.6eV based on the exhibit semiconducting behaviour and the conductivity increases with the Ce content in the compound. the in content Ce the with increases conductivity the and behaviour semiconducting exhibit the conventional ceramic route. The electrical conductivity measurements showed that these compounds these that showed measurements conductivity electrical The route. ceramic conventional the Ca – Ce – Ti – M – O (M = Nb or Ta) system was synthesized in different stoichiometric compositions by compositions stoichiometric different in synthesized was system Ta) or Nb = (M O – M – Ti – Ce – Ca (ii) Development of Novel Semiconducting Oxides photoelectrolysis of water etc. A new series of pyrochlore type semiconducting ceramic oxides in NATIONAL INSTITUTE OF INTERDISCIPLINARY SCIENCE & TECHNOLOGY Thiruvananthapuram 72 72 particles of magnetite was synthesised by surfactant assisted coprecipitation method. Magnetite crystals inhibit clustering in aqueous suspensions by normal techniques. However, monodisperse single domain to difficult was It distribution. size the over control with methods various by synthesised successfully applications ferrofluid for slurry Magnetite Nanoparticulate shown inthefigurebelow. near to room temperature. The magnetic entropy change increases with increasing magnetic field as method and the measured MCE of the material showed state large solid magnetic by entropy prepared change was at LCMO adopted. temperature were manganites preparing for methods physical as for up scaling up taken of various synthesis was method for preparing different project manganites. Various new chemical as a well purposes refrigeration magnetic for manganites of utilization magnetocaloric effect (MCE) and its potential for application as magnetic refrigerant. Based on the Applications 1.4.Magnetic for Materials and understanding of the new materials. Consultancy services were also rendered to outside to rendered also were services Consultancy materials. new the of understanding and organic and inorganic materials have been carried out using SEM/EDS for the development the for SEM/EDS using out carried been have materials inorganic and organic The micro structural and micro chemical characterization of wide variety of samples both samples of variety wide of characterization chemical micro and structural micro The ueprmgei (ige rsas mgeie (FeO.Fe magnetite crystals) (single Superparamagnetic Rare earth manganite perovskite has attracted considerable attention because of its high agencies such as VSSC, Kerala University, Medical and Dental College etc. College Dental and Medical University, Kerala VSSC, as such agencies -∆U*L1mi"M+ 2 4 6 8 Variation inmagneticentropychangewith field Uqnkf"uvcvg"u{pvjguku NEOQ" 6 7 8 9 : 4;2 4:2 492 482 472 462 V*M+ 2 O 3 i te ie ag 63 n was nm 6-30 range size the in ) "6V "5V "4V "3V "7V Materials andMinerals ANNUAL REPORT 2007-2008 73 73 is in progress. in is irr and H and C based multifilamentary based 2 Materials and Minerals Materials superconducting wires with transport critical 2 and critical temperature 38.5 K was successfully made by a powder- a by made successfully was K 38.5 temperature critical and 2 superconducting wire development 2 (Current ratings from 50 to 1000 A at 77 K) ) >10,000 A/cm >10,000 ) C The superconducting current leads developed by NIIST in collaboration with RRCAT The project envisages to study the technical feasibility of making MgB making of feasibility technical the study to envisages project The The project has the main objective of developing general purpose conduction cooling current density (J density current Feasibility study on Feasibility MgB in-sealed-tube (PIST) method. Development of long length wires with higher J higher with wires length long of Development method. (PIST) in-sealed-tube wires. Short length sheathed Fe multifilamentary MgB superconducting current leads of ratings 50 A, 100A, 200 A, 500 A and 1000 A at 77 K and 100A, superconducting current high in application for respectively K 64 at A 2000 and A 1000 A 500 A, 200 system. These were successfully developed for the first time in the country and the prototypes were subjected to all the testing and evaluation procedures at NIIST and further validated The by RRCAT. products were delivered to the user. 1.5. Material for1.5. Superconducting applications Development of superconducting current leads for DAE of size ~10 nm synthesised by coprecipitation were purely superparamagnetic (single crystalline) as magnetisation saturation High loop. hysteresis the in magnetisation remnant zero the by indicated was and small remnant magnetisation in the hysteresis loop were indicative of multidomain nature in 30 technique. synthesised through flash combustion nm magnetite particles NATIONAL INSTITUTE OF INTERDISCIPLINARY SCIENCE & TECHNOLOGY Thiruvananthapuram 74 74 exhibiting MITandmanymodifiedsuperconductors withhighlyimprovedproperties. compositions several in mechanism conduction of identification the to led results The out. carried were properties superconducting and transport structure, crystal (MIT), transition metal-insulator on superconductor Bi,Pb)-2212 in ication modif earth rare and transition metal-insulator on research Basic 2007-08. during analysed were samples ~3500 of number total A Colleges. and CSIR Universities other Laboratories, several and Trivandrum TTPL, Pune, TCS, includes that organizations support. outside and Analytical XRD Dark fieldHRTEM imageofMgB Studies on the effects of rare earth substitution at different sites of (Bi,Pb)-2212 superconductor Magnetization plotsMgB Ocipgvke"oqogpv"*gow1eo5+ /5 /4 /3 2 23242526272 Extended XRD analytical support to different divisions of the laboratory the of divisions different to support analytical XRD Extended 2 showingnanointragraininclusionswhichactsasfluxpinningcenters 2 samples showingsharpsuperconductingtransitions Vgorgtcvwtg"*M+ "ODVD32 "ODVD7 "ODVD3 "ODVD2 Materials andMinerals " ANNUAL REPORT 2007-2008 75 75 Materials and Minerals Materials Al-SiC functionally graded prototype brake rotor disc Al-SiC functionally graded prototype brake rotor discs containing 20% SiC particle were Boron carbide is one of the potential neutron absorption materials used in nuclear applications. nuclear in used materials absorption neutron potential the of one is carbide Boron has to be developed. processed by vertical centrifugal casting and supplied to M&M. The characterization of Al-20% SiC functionally graded composite disc showed enhanced structural and mechanical properties towards the outer periphery of the casting. The presence of higher concentration of silicon carbide particles towards the outer periphery provided higher hardness, tensile and compressive properties compared of area braking the in properties improved The region. depleted particle having periphery inner the to the disc enhance its overall performance and were discs the of tests road The efficiency. braking carried out by fitting it to a multi utility vehicle. Structural integrity of the disc was very good wear remarkable no was there and testing during on the disc surface. The braking efficiency of the FGM disc was slightly lower compared to that of cast iron disc due to non compatibility of the conventional brake liner used for cast iron. disc FGM Al to suitable more liner brake Alternate Processing and Characterization of prototype Al-SiC FGM Brake Rotor Discs for automotive applications. Boron carbide reinforced metal matrix composites (MMC) are uniquely suited as a structural neutron mechanical enhanced as well as absorption neutron of properties tailorable where material, shielding properties such as high strength, stiffness and hardness can be obtained. Boron carbide reinforced microstuctural The method. casting stir using fabricated successfully were composites matrix aluminium 356 Al, pure commercially as such matrixes the in particles of distribution uniform showed evaluation cast and 6061 wrought aluminium alloys. The addition of boron carbide increased the hardness in evaluation is in progress. Further both as cast and heat treated condition. Processing of Boron Carbide Reinforced Aluminium Matrix Composites for Applications. Nuclear 2. LIGHT METALS, ALLOYS AND COMPOSITES ALLOYS 2. LIGHT METALS, NATIONAL INSTITUTE OF INTERDISCIPLINARY SCIENCE & TECHNOLOGY Thiruvananthapuram 76 76 aerospace, automotive,defenceandgeneralengineeringapplications. in structures various for properties enhanced with joints materials dissimilar making for be applied can FSW by joints weld dissimilar formation The interface. alloy to weld same the at occurred failure cases both In materials. base of that than values lower showed weld of specimen transverse Impact toughness testshowedthevalueincreasedtwicethatofbasematerialsandtensile welding. stir friction during place taken had phases Si eutectic and aluminum primary of and composite due to finer and low volume fraction (5%) of SiC particles, even though the refinement compared to the base composite. The hardness values of weld zone were found in between base alloy finer were particles the and zone stir the in distributed uniformly were particles SiC materials. base to compared dispersed uniformly more phases Si eutectic fine and structure dendritic without grains aluminium primary recrystallized fine showed joint dissimilar MMC SiC (356)- Al to alloy Al 356 of (Figure) and similar joints of alloy to alloy and composite alloy to composite were carried cast out. The stir zone 356Al with MMC SiC vol% (356)-10 Al of joint dissimilar of properties and structure on parameters process FSW of effect the on investigation detailed A welding. fusion the than better are region of material. The weld quality is excellent due to porous free joint and the mechanical properties tool rotates and moves forward along the weld seam with a high speed of stirring producing a plasticized Applications Engineering Composites SiC for 10% AI(356)- and Alloy AI(356) WeldedStir Friction of of Joint Development Material Dissimilar and Similar Friction stir welding (FSW) is an advanced solid-state joining technique, in which a threaded a which in technique, joining solid-state advanced an is (FSW) welding stir Friction 356Al -356Al/10%SiCpplates joinedbyfrictionstirwelding. Materials andMinerals ANNUAL REPORT 2007-2008 77 77 Materials and Minerals Materials Optical micrograph of the in-situ Al-AlN composite after 4 hours nitridation Al-AlN in-situ composite has been successfully synthesized by bubbling nitrogen gas in Al TEM photograph showing hexagonal morphology of the extracted AlN particles from Al-AlN in-situ composite TEM photograph showing hexagonal morphology of the extracted AlN particles from process parameters is in progress. of the extracted particles confirmed the formation the work in optimizing of AlN in the melt. Further The sizes of the AIN particles were found to be in the range from nano to a few microns. XRD analysis XRD microns. few a to nano from range the in be to found were particles AIN the of sizes The (SEM), TEM /Energy Dispersive X-ray analysis. The morphology of the particles was found to be hexagonal. be to found was particles the of morphology The analysis. X-ray Dispersive /Energy TEM (SEM), settled particles were dried and examined by Diffraction X-ray (XRD), Scanning Electron Microscopy reaction products were extracted from the casting by leaching out the Al matrix using NaOH. Then the Then NaOH. using matrix Al the out leaching by casting the from extracted were products reaction Synthesis and characterization of in-situ composites Al/AIN the manner, detailed a in products reaction the of morphology and size the examine to order In melt. NATIONAL INSTITUTE OF INTERDISCIPLINARY SCIENCE & TECHNOLOGY Thiruvananthapuram 78 78 Mat Mat Squee Squee Mat rpris u wt mjr ih eprtr bhvor rbes Itouto o temly stable thermally of Introduction problems. behaviour temperature high major with but properties foundry and chemical mechanical, excellent offers and alloys magnesium in system alloy major the of one is 1%Zn-0.2%Mn) AZ91(Mg-9%Al- alloys, Mg the Among metals. structural used commonly many to compared ratio strength-to-weight high the and lightness the to due industry automotive Development Alloy Magnesium also foundtobeintheacceptablerange. of theplatesmeasuredusingHeyins’interceptmethodwasfoundtobebetween5and6which size grain micro ASTM The microstructure. acceptable revealed plates rolled alloy Al 7020 AFNOR on in space applications. The microstructural analysis carried out using optical metallographic techniques properties of both ferrous and non ferrous alloys and their components to understand their performance applications space for metallic materials of characterization Metallurgical and thecompositecouldbeattributedtorefinementofmicrostructurewithinmaterial. alloy cast squeeze the in observed properties mechanical improved The composite. the and alloy the both in level porosity low very and refinement microstructural the pressure level of 100 MPa was found to be sufficient to get resulted when pressure was applied during solidification. A composite the of case the in particles SiC of distribution defects such as shrinkage and gas porosities and improved casting of elimination refinement, microstructural The image analysis and mechanical properties by tensile testing. microstructural characteristics using optical microscopy and to respect with evaluated was solidification during pressure squeeze of effect The pressures. different at cast SiC particles of average particle size of 23 µm were squeeze Squee Mat Mat Squee Squee r r r r r ix Comp ix Comp ix ix Comp ix ix Comp ix Comp ix z z z z z The use of magnesium has grown considerably since early 1990 and continues to rise in the in rise to continues and 1990 early since considerably grown has magnesium of use The The objective of the project is the microstructural investigation and characterisaton of mechanical Aluminium 2124 alloy and its composite with 10% e e Cast Cast e Cast e e Cast Cast ing ing and and Char Char ing and Char ing ing and and Char Char osit osit osit osit osit e e e e e a a a a a ct ct ct ct ct e e e e e r r r r r iz iz iz iz iz at at at at at ion ion of of ion of ion ion of of A A A A A l l 2124 2124 l 2124 l l 2124 2124 Macro photographof2124-10SiCpcomposite A A A A A llo llo llo llo llo D" V" squeeze castatdifferentpressures. y y and and 2124-10%SiCp 2124-10%SiCp Met Met y and 2124-10%SiCp Met y y and and 2124-10%SiCp 2124-10%SiCp Met Met Materials andMinerals f" e" d" c" 100 100 75 45 0 Squeeze Pressure, MPa al al al al al ANNUAL REPORT 2007-2008 79 79 content. The employment of 2 Materials and Minerals Materials content was analyzed. Several hydro cyclone separation 2 . The composition of overflow and underflow collected for a fixed a for collected underflow and overflow of composition The . 2 . A few separation experiments were also carried out at BMRC, IREL at Kollam 2 The iron oxide produced during the aeration rusting of metallised ilemanite in sufficient In order to address the challenge of contamination of Iron oxide in ilemanite stream, and As part of the major research activity based on ilemanite for synthetic rutile, the following quantities has to be utilised as a salable product for additional revenue generation as effective well disposal. Experiments as were carried for out in the laboratory for pelletisation production. of DRI iron oxide for and stock feed a as this use effectively to temperatures various at pellets the of induration and agglomeration its for technique suitable more be to found was pelletiser disc a using Pelletisation time interval in terms of iron oxide and TiO in resulted pressures inlet as well as diameter apex and vortex of combinations various at experiments best results of overflow containing 61.45% and Fe (Total) 10.45% TiO (WHIMS). using their combined hydrocylone separation and wet magnetic separation varying at induration subsequent and oxide iron of pelletisation on Investigations temperatures ilemanite stream in hydro cyclone separation of hydrated iron oxide and beneficiated ilemanite after aeration rusting in the commercial plants, hydro cyclone separation was carried out at various inlet kg/cm 4 to 1 from ranging pressures 64.38% containing product overflow a in resulted experiment the of one in dispersants based silicate and 8% TiO (Total) Fe investigations were carried out: Optimisation of ofseparation and iron rustedhydrocyclone oxide ilemanite 3. MATERIALS FROM BEACH SAND MINERALS 3. MATERIALS intermetallics in the microstructure through minor alloying additions is an effective way to improve its improve to way effective an is additions alloying minor through microstructure the in intermetallics high temperature behaviour and an investigation was carried out with the addition of Si, Sb and Sr elements in AZ91 alloy to study the effect of obtained were these properties temperature high elements as well on as properties creep the the in high improvement Substantial temperature behaviour. with individual and combined alloying additions. Addition of Si and Sb greatly increased alloyAZ91 have (LPC) the Cast Pressure Low total of characteristics fatigue Besides, alloy. AZ91 the of life creep also been evaluated. It was also found that LPC AZ91 alloy yielded better fatigue properties gravity cast AZ91 alloy. than NATIONAL INSTITUTE OF INTERDISCIPLINARY SCIENCE & TECHNOLOGY Thiruvananthapuram 80 80 . wtot prcal afcig h rsig fiiny f h pout hc i tr significantly improved theeconomyofprocess. turn in which product the of efficiency rusting the affecting appreciably without 0.4 duration. This clearly suggested that, the coal rate hitherto employed at 0.6 to 0.75 can be reduced to FeCl 2% in rusting /coal ratio at 40% provided a metallised product with 67% metallisation. This product on subsequent rotary kiln in the metallisation of ilemanite. Reduction experiments carried out at 1050 °C using ilemanite kiln rotary the in Metallisation cokeratepossible of the decrease on Investigations andtemperaturethe during heated and dried pellets at 1100 to be properly arrived at in order to render pellets free from excessive swelling, cracking etc. Firing of pre mixture was found iron oxide optimum. Schedule of drying, pre heating and firing of green pellets had level ofmaximum10%forironorefines.Additionbentonite@1%byweightasthebinderin moisture recommended the than higher was This size. mm 10-20 of pellets green of formation the The fines. ore investigations revealed that, a moisture level iron of minimum 25% in the iron the oxide feed was required for than higher slightly were required binders and moisture of quantity the Synthet Synthet Synthet capacity of its plant at Aluva and the commercial plant is expected to be commissioned within 2 years. By adopting the new technology at an estimated cost of 100 crores, CMRL proposed to double the and ratioactivitylevelsacceptabletoInternationalstandards. new process in addition to the production of quality grade synthetic rutile with more than 97% TiO CMRL would be able to achieve near zero effluent status owing to very low acid consumption in the recovered assalablebyproductrenderingtheprocess flowsheetmoreeco-friendly. The modified process is unique in terms of by product utilization as all the iron values from ilemaniteare 2 decades, was subsequently modified jointly by NIIST and CMRL to suit the available raw materials. The new technology ,developed essentially based on sustained and focused research spanning over of technology. NIIST on January 16, 2008 in the presence of the Director and Scientists at involved organised function in a the at Director,Aluva Managing development CMRL, Kartha, Sasidharan N. S. Shri. to CSIR Detailed technology transfer document was handed over by Prof. S. K. Brahmachari, Director General, synthetic rutilefromilemanite. transfer agreement with CMRL for the commercialisation of a new processes for the production of of capacity the view into taking production, CSIR level of of investment, environment history impact and the quantum of in royalty payable transfers is the technology technology biggest the of One Synthet Synthet Coal is used both as the reductant and the fuel to sustain the reduction temperature in the in temperature reduction the sustain to fuel the and reductant the as both used is Coal ic R ic R ic ic R ic ic R ic R ic ut ut ut ut ut 2 ile t ile t ile ile t ile ile t ile t ile solution resulted in a beneficiated product containing 11% Fe (T) after 8 hours 8 after (T) Fe 11% containing product beneficiated a in resulted solution ec ec ec ec ec hno hno hno hno hno log log log log log o C was necessary for imparting sufficient shatter strength to the pellets. y t y t y y t y y t y t y r r r r r ansf ansf ansf ansf ansf e e e e e r r r r r ed t ed t ed ed t ed ed t ed t ed o CMR o CMR o o CMR o o CMR o CMR o L L L L L Materials andMinerals 2 ANNUAL REPORT 2007-2008 81 81 Materials and Minerals Materials 65 kg. This has been achieved through the /g. Particle size of the sillimanite falls between 90-250 µ. X-ray diffraction 2 58.12 % by weight. The total iron content was 0.57% by weight. EDAX analysis EDAX weight. by 0.57% was content iron total The weight. by % 58.12 3 O 2 Aluminium – silicon alloys are extensively used in automotive applications as it reduces the The envisaged objective is to develop a palm climber with a speed of 12 trees/ hr. A prototype A hr. trees/ 12 of speed a with climber palm a develop to is objective envisaged The A new solvent based contact adhesive based on blend of phosphorylated cashew nut shell A plasma reactor for the reduction melting of sillimanite was procured and commissioned 37.18% and Al and 37.18% 2 synchronized operation of 3 pneumatic double acting pistons operating at a pressure of 0.8 MPa. The MPa. 0.8 of pressure a at operating pistons acting double pneumatic 3 of operation synchronized Development of Climbing Coconut Bike of this machine was developed with a lift capacity of liquid pre-polymer, natural liquid rubber pre-polymer, and polycholoroprene rubber (PCNL/NR/CR), which has higher T- flexible bonding for developed was 998), SR (Fevicol adhesive commercial a to compared strength peel substrates such as vulcanized leather rubber, and rexin. The adhesive, by appropriate compositional was scaled up to 20 kg level. variations, can also find various applications. The synthesis of PCNSL 4. SOCIETAL PROGRAMMES 4. SOCIETAL Development of PCNSL adhesives based contact showed Al content varied from 25.8 % by weight in 170 ASTM fraction to 39.47% by weight in 80 from 13.56 in 170 ASTM size fraction to 22.1% by weight in 80 ASTM fraction and Si content varied furnace induction vacuum a using reduction carbothermic on experiment Preliminary fraction. ASTM confirmed alloys of pattern diffraction X-ray Al. 65% and Si 23% with alloy silicon - aluminum produced that the major peaks of Si and Al. sillimanite for conducted also were experiments reduction preliminary few A period. reporting the during in the above reactor. The alloy samples collected were subjected to chemical analysis and investigations. XRD weight of the automobile leading to reduced fuel consumption. Detailed investigations were initiated were investigations Detailed consumption. fuel reduced to leading automobile the of weight at developing a process for the production of aluminium – silicon master alloys physical from systematic sillimanite A by process. plasma fast and efficient energy highly employing reduction carbothermal and chemical characterization of sillimanite mineral revealed that the mineral is brownish in colour a has and nature in conchoidal is It gm/cc. 2.1344 density bulk with 3.21 of gravity specific a has and surface area of 0.12 m Physical and chemical characterisation Physical of and characterisation chemical sillimanite mineral of composition a shows analysis chemical Wet Sillimanite. of peaks characteristic the all shows pattern SiO NATIONAL INSTITUTE OF INTERDISCIPLINARY SCIENCE & TECHNOLOGY Thiruvananthapuram 82 82 with thefinancialassistanceofCoconutDevelopmentBoard. be accommodated in the present model. Development of a model, to suit to tree trunk, is in progress and a descending speed of 3.8m/ min. An approximate variation of ±10% in pole diameter could also present model is suitable of climbing on a pole of 63 mm diameter with a climbing speed of 6m/min. The machineclimbingwithaweightof65kg. 2007) was organised2007) was by LightAlloys and advanced metals, ceramics, polymers and bu 0ivtdlcue ntefield of About inthef 60invited lectures Composites duringOctober 24- Section International Conference on Advancedon Conference International conference was attended was bymorethan conference Materials and Composites (ICAMC - MaterialsCompositesand (ICAMC composites havebeen given. Aspecial 400 delegates Indiaandabroad. from 26,2007, Thiruvananthapuram. The session on metal matrix compositessession onmetal matrix was arranged. Materials andMinerals ANNUAL REPORT 2007-2008 83 83 PROCESS ENGINEERING PROCESS AND ENVIRONMENTAL TECHNOLOGY AND ENVIRONMENTAL to achieve in the generation and application of knowledge at the Science-Computation- Two silica sand samples (viz., White sand and Yellow sand) supplied by M/s GSRC was evaluated was GSRC M/s by supplied sand) Yellow and sand White (viz., samples sand silica Two other groups within the laboratory other R&D programmes of the laboratory Design and development of industrial effluent treatment processes & plants Design and development of industrial effluent treatment processes & solid wastes Design and development of biological treatment systems for liquid and Design and development of odour and VOC control systems Environmental impact assessment studies and services Bio and Chemo-informatics of Dioxin and other POPs Analytical protocols and emission control Development of decentralized processing systems for rural applications Development of decentralized processing processes and materials molecules, of design and understanding for tools software of Development to support computational provide to and use commercial for software technical of Development Scale-up of laboratory scale processes to commercial levels Scale-up of laboratory scale processes Chemical engineering investigations on unit operations and unit processes for minerals and ocusing Environmental technology Environmental z z z z z research Dioxin z z Computational modeling and simulation z z Objectives : Objectives engineeringChemical & process z z F publications/ impact high products, software processes, competitive to leading interfaces Engineering applications. upgradation of industries and societal patents, technology 300 and plus 125 fractions. These were blended to obtain the glass making sand composition. This subjected to wet sieving and fractionation so as to get the required minus 600 plus 300 and minus for their use in glass making. Both samples contained iron and titania impurities. The samples were Evaluation for the benef iciablity of silica sand 1. CHEMICAL AND PROCESS ENGINEERING NATIONAL INSTITUTE OF INTERDISCIPLINARY SCIENCE & TECHNOLOGY Thiruvananthapuram 84 84 Delhi inMarch2008.Further development isunderway. New BMPTC, M/s sponsor, the to transferred was how know process The viable. economically was process the that shows analysis cost The resistance. ion chloride its for particularly concrete the for TPD of microsilica. Tests showed that the material produced at the Institute was an excellent pozzolan 10 produce will which plant processing Tonshusk 59 rice a (TPD) Perfor Day done been has design process commercial data, plant micropilot the on earlier.Based reported was scale plant micropilot husk from rice silica reactive of production the process a for of Development brightness of65.0%ISO. Further classificationandvalue additionworkisinprogress. a measured cyclone std. inch 2 of solids slurry overflow the %ISO, 61.0 of brightness a measured clay raw the While stream. product the in micron 2 minus of quantum the assessing for stage every using a 2 inch standard hydrocyclone. The particle size of the overflow slurry solids was determined at classified again was cyclone stub the of overflow The grits. medium the eliminating for hydrocyclone stub inch 2 a using classified is screen the from slurry undersize The grits. coarse remove to order in Valuechannelwaste of of “Indian”addition utilization optimum and chinaclay 0.95%. Adetailedreportontheevaluationsubmittedtosponsor. permissible the value of 0.1% than as per higher IS 488: 1980. is Incidentally, the Fewhich 0.15% was value iron final the since grade making glass to value-added be not could sand yellow The 98.9%. was assay silica The sand. making glass level II Grade for same Fe The separation. magnetic intensity high wet to subjected and sieved attrited, was sample blended 2 O 3 in white sand could be reduced to 0.05% from a raw sand value of 1.4% thus upgrading the upgrading thus 1.4% of value sand raw a from 0.05% to reduced be could sand white in h poes o te rdcin f ecie iia mcoiia fo rc hs dvlpd at developed husk rice from (microsilica) silica reactive of production the for process The The raw clay sample supplied by M/s KCCPL, Kannur was subjected to blunging and screening (source ofsilica)beforeprocessing Microsilicaafterprocessing Process Engineering&EnvironmentalTechnology Rice husk 2 O 3 assay of the raw yellow sand was ANNUAL REPORT 2007-2008 85 85 Drier for producing ball copra Virtual Casting Looking into invisible worlds into Looking through Computer Simulations….. to complement VirtualFeed Process Engineering & Environmental Technology Environmental & Engineering Process The R&D activities comprise of investigation on manufacturing processes and natural phenomena natural and processes manufacturing on investigation of comprise activities R&D The Reverse flow natural convection driers have become a convenient tool for the drying needs of needs drying the for tool convenient a become have driers convection natural flow Reverse Assistance was given to public on the use of NC driers NC of use the on public to given was Assistance for their different drying needs. Assisted standardizing the drying in conditions for making hand Nadu. rolled tea leaves in cottage scale to an user from Nilgiri, Tamil Based upon the studies conducted, a prototype drier for the accelerated drying of coconuts to make ball copra was designed and fabricated for the drying of husk) with (coconuts coconuts whole of numbers 3000 per batch to make ball copra within a time span of 3 to 4 months. The full capacity drying trials are being carried out. The modified NC drier for drying of rubber sheets cost low This improved. further was year last reported The bricks. concrete cement hollow of made was drier drier can dry 30 numbers of rubber sheets within a time span of 2 days and the holding capacity is 60 to out works drier the of cost MRP The sheets. rubber be Rs.15,000/- per unit, all inclusive. z z z feeders positioned appropriately in the mold. The design and positioning of feeders is the most critical Metals shrink on solidification; therefore the casting process requires that extra metal is supplied through Metals shrink on solidification; therefore the casting process requires that Modeling Modeling of Metallurgical Processes Software for casting process design – engineering, chemistry and biology. through computer simulations in a wide range of areas like metallurgical engineering, chemical 2. COMPUTATIONAL MODELING AND SIMULATION 2. COMPUTATIONAL are given below: Societal Societal Programmes developments recent The etc. group women’s employed self industries, cottage and scale small farmers, NATIONAL INSTITUTE OF INTERDISCIPLINARY SCIENCE & TECHNOLOGY Thiruvananthapuram 86 86 role indeterminingthesizeand shapeofmicroporosity. growing bubbles with the solidification microstructure that played a critical of interaction the and melts solidifying in bubbles gas of redistribution and movement the were simulation the into brought features novel microporosity formation in castings through computer simulations. The General Motors Corporation USA has sponsored a project for investigating of fatigue strength in critical regions due to the presence of microporosity. casting the engine block, one of the problems they face is the reduction simulations computer through castings in formation microporosity studying – metals solidifying in Bubbles refined usingfurthersimulations. algorithm finds a class of feeder dimensions such that the yield is maximized. The design can be iteratively and modulus of a feeding section, the size of the feeder is calculated. For every feeding section, a genetic feeder.separate a requiring section” volume From“feeding the a being cluster each clusters, into casting the divides algorithm recognition pattern novel a Casting, Virtual from results simulation the on Based of the rigorous heat transfer analysis of simulation any software is that of simulations can limitation only test a One given design academia. – it as cannot generate the well design. as industry of attention the attracting is software The design. feeder of adequacy the testing for environment virtual a provides and process casting the simulates that software, the out brought institute the ago years Three design. process casting of aspect Feed Feed that createsasimulation-basedinitialdesignoffeedersbyintegratingthecomplementarystrengths As automobile industries switch over to light weight alloys for alloys weight light to over switch industries automobile As The clusteringofacomplexcastingintosevenfeedingsections Process Engineering&EnvironmentalTechnology Virtual Casting Virtual and practically derived design rules was developed. the spacebetweengrowingsolid grains giving risetocomplexshaped porosity. A Bubble(showninpurple)grows in Virtual Casting Virtual Virtual ANNUAL REPORT 2007-2008 87 87 radial magnetic fields Velocity profiles developed Velocity under combination of axial and Process Engineering & Environmental Technology Environmental & Engineering Process A computational tool developed allows simulation of the kiln performance over a wide range wide a over performance kiln the of simulation allows developed tool computational A When alloys are cooled through their solidification range under range solidification their through cooled are alloys When A cellular automaton simulation model was used as a virtual experimental set up to study by the injected coal particles height along the length of the kiln (c) Pneumatic coal injection from the discharge end which predicts the trajectories and heat generated heat and trajectories the (c)predicts which end discharge the from injection coal Pneumatic (b) mixture in the rotary kiln using discrete element method The mixing behavior of coal/ilemanite (a) The granular flow of ilemanite/coal mixture in rotary cylinder which predicts the variation of bed of design and operating parameters. The tool has various sub models for: of design and operating parameters. The tool has various sub models Design of rotary kiln for Ilemanite Metallisation Models of Chemical Processes Solidif ication Morphology in Electromagnetically Stirred Alloys different very are that morphologies assumes solid the stirring, constant from the dendritic structures that ensue from normal solidification. project Hyderabada Laboratory, sponsored Metallurgical has Defence result that morphologies solidification and profiles velocity the study to from electromagnetic stirring of alloys in the solid-liquid state. Three types of coil design were studied: (1) coils that produce a radial magnetic field, (2) coils that produce an axial magnetic field and (3) combination of both. The components of the force analysis CFD vector a to were input were forces These cases. three all for calculated to calculate the velocity fields. growth of gas bubbles in solidifying Aluminum castings. The model assumes that gas porosity originates porosity gas that assumes model The castings. Aluminum solidifying in bubbles gas of growth from pre-existing micro-bubbles that grow by diffusion of hydrogen from the growing solid into the imposed constraint space the as well as hydrogen of diffusion the for available time finite The bubbles. specially rules with model automaton cellular The bubbles. the of growth the limit solid growing the by grid. fine a on explicitly interfaces bubble-liquid and solid-liquid the tracks growth, bubble for adapted seen are itself finds it which in environment microstructural the and bubble pre-existing the of size The the final size and morphology of porosity. to be the critical factors that determine NATIONAL INSTITUTE OF INTERDISCIPLINARY SCIENCE & TECHNOLOGY Thiruvananthapuram 88 88 (MFR) wasusedtomodelthe impellerandtankregion. reference of frame multiple A approach. Multi-fluid Eulerian-Eulerian using reactor agitated mechanically wall andlowervalueofthatatthecenter. wall and maximum upward velocity at the center of the column and higher value of solid holdup at the the at velocity downward with pattern axi-symmetric exhibits profile velocity solid averaged time the that demonstrated pattern flow predicted The approach. Eulerian–Eulerian multifluid the employing the model hydrodynamics ofliquid–solidfluidizedbed. to proposed was methodology CFD comprehensive A investigated. was bed fluidised liquid in motion solid on models drag interphase similar operating conditions. The influence of v suspension inanequivalentstirredtankcontactorat bed was also compared with energy required for solid Energy required for solid expansion in liquid fluidized energy flowsduetovariousdissipationmechanisms. and mass of conservation verifying for computed were regions annular and core the in balance mass Solid framework. Eulerian–Eulerian using bed prediction offlowpatternsinaliquid–solid fluidized agitatedmechanically bedand reactors fluidized of simulation CFD Multiphase after validatingitsperformanceandpilotscaleotherreportedliteraturevalues ilemanite synthetic of TPD 350 of capacity a for designed was kiln rotary a tool, computational this and primary loads, heat various the predicts which calculations balance mass and Heat Overall (d) secondary airrequirementsandexhaustgasvelocities CFD simulations were carried out to study solid suspension in Liquid-Solid and Gas-Liquid- Solid Gas-Liquid- and Liquid-Solid in suspension solid study to out carried were simulations CFD by out carried was bed fluidised liquid in motion solid and hydrodynamics of simulation CFD the for out carried were simulations CFD The varioussubmoduleswerevalidatedwithavailableexperimental/pilotplantresults.Using Process Engineering&EnvironmentalTechnology arious Typical timeaveragedazimuthallyaxialsolid velocity profile ANNUAL REPORT 2007-2008 89 89 Process Engineering & Environmental Technology Environmental & Engineering Process Solid suspension height predicted by CFD for different impeller rotational speeds. Solid suspension height predicted by CFD Solid flow pattern obtained from CFD in mechanically agitated Gas-Liquid- Solid reactor Solid flow pattern obtained from CFD in Theoretical methods such as quantum mechanical (QM) ab initio, density functional theory As part of a CSIR Inter Agency project “New insights in Cancer Biology: Identification of novel of Identification Biology: Cancer in insights “New project Agency Inter CSIR a of part As assessing therapeutic strategies. simulations are expected to serve as a virtual experimental facility for testing different hypotheses and hypotheses different testing for facility experimental virtual a as serve to expected are simulations Computational Chemistry hardware advanced in implemented (MD) dynamics molecular and (MM), mechanics (DFT),molecular and function. The breakdown of the co-operative behavior will lead to diseases like cancer. These the agents represent different types of cells that act co-operatively to produce the normal tissue structure tissue normal the produce to co-operatively act that cells of types different represent agents the simulation for collective cell behavior with application to cancer development. In these simulations targets and development of target based molecular medicine” the Institute is developing a multi-agent a developing is Institute the medicine” molecular based target of development and targets Computational Biology Simulating Collective cell behavior and Cancer NATIONAL INSTITUTE OF INTERDISCIPLINARY SCIENCE & TECHNOLOGY Thiruvananthapuram 90 90 bidentate), the outer-sphere binding mode showed the highest binding energy (BE) for hydrated Li hydrated for (BE) energy binding highest the showed mode outer-spherebinding the bidentate), inner-sphere and monodentate, inner-sphere (outer-sphere, studied combinations metal-binding three the Among states. dianion and anion the in modeled pair base GC a and units, sugar three Li as such ions metal alkali (iv) DNA metal-ion interactions: respectively ( and respectively properties, withdrawal electron and (+ + with ligands namely, categories, four into ligands the of classification general a to leading a variety of phosphine ligands (PR (iii) Stereoelectronic profile phosphine ligands: PAHcarcinogenesis, viz,K,Lregionandthebaytheories( of theories popular two the of supportive is feature This PAHs. of property the deactivating carcinogenic were regions N and L while activating were regions M and K the model that QSAR suggested The regions. N and M, L, K, to classification a to leading rings aromatic of features electronic characteristic the revealed systems PAH of variety a on conducted study QM systematic frequently found in the biosphere mainly due to incomplete combustion of biomass and fossil fuels. A (ii) Polycyclic aromatic hydrocarbons (PAHs) Chem ( system protease-inhibitor the of region site active bound Asp the at occurring dynamics H-bond the enhanced it as action drug of mechanism the on influence direct a had molecules water QM/MM hybrid and MD methods were used for the study. The simulations showed that the conserved understand theroleof“conserved”structuralwatermoleculesinligandbindingmechanism.The i) hypothesis, etc.Thefollowingarethesignificantcontributions. bioorganic molecules, to test predictive power of theoretical techniques, to prove or disprove conceptual molecules, better understanding of quantitative structure activity relationships (QSAR) in organic and photoactive of design the formations, bond C-C stereoselective for organocatalysts powerful of pursuit of ambitious goals such as optimizing new homogeneous transition metal catalysts, in development solved were problems Several reactivity. and structure chemical model to used been have setups S HIV protease-inhibitor complexes: protease-inhibitor HIV eff ), (+ . 2008 E eff , - , Inorg. Chem 29 S eff , 1840). ), (- E eff , + . S 2007 + eff , Na , ), and (- , QM/MM approach was also used to study the interactions of hydrated + 3 46 ) was achieved using a combined approach of QM and MM methods, , and K and , Process Engineering&EnvironmentalTechnology , 10800). E eff A theoretical study was conducted on six such complexes to complexes such six on conducted was study theoretical A , - + S with a DNA fragment containing two phosphate groups, phosphate two containing fragment DNA a with eff ), where plus and minus signs indicate electron donation : These are one of the most potent carcinogenic mutagens The determination of the stereoelectronic profile of E eff and J. Comp.Chem. S eff are the electronic and steric effects, steric and electronic the are 2008 , 29 , 1808). J. Comp. J. E eff + , ANNUAL REPORT 2007-2008 , - 91 91 N , 6472). interactions π 111 , , 6707). , 48 , 2007 Bull. Chem. Soc. Jpn. Soc. Chem. Bull. 2007 interactions. Theoretical π , A theoretical interpretation theoretical A Molecular modeling using Polymer J. Phys. Chem. A ions preferred the inner-sphere monodentate + and K + -isopropylacrylamide-co-maleimide -isopropylacrylamide-co-maleimide (NIPAM-co-MI) and N Host-guest interactions in an azapolycyclic system was investigated was system azapolycyclic an in interactions Host-guest Process Engineering & Environmental Technology Environmental & Engineering Process , 1172). The intramolecular hydrogen bond (H-bond) energies in several 3 , , 14933). 2007 111 , interactions: π 2007 , respectively). These data showed good agreement with the previous experimental findings experimental previous the with agreement good showed data These respectively). , + , 484). 80 and K and + J. Phys. Chem. C J. Chem. Theor. Comput. J. Chem. Theor. (viii) Surface modeling of alkoxy substituted phenyleneethynylene: results showed good agreement with the experimental structure of the complex ( complex the of structure experimental the with agreement good showed results 2007, alkoxy the of organization dimensional two understand to out carried was method AM1 semiempirical force driving the that suggested strongly study the from results The phenyleneethynylene. substituted CH… alkyl of modes different existence the was pattern organization self observed the for ( binding modes to the phosphate group of the anionic DNA fragment (BE = 87.9 and 98.2 kcal/mol for kcal/mol 98.2 and 87.9 = (BE fragment DNA anionic the of group phosphate the to modes binding Na ( ions (103.1 kcal/mol) while the hydrated Na behavior: (LCST) temperature solution critical lower of Interpretation (v) of the contrasting LCST behavior of isopropylacrylamide-co-maleic anhydride (NIPAM-co-MA) was obtained by quantum mechanical (QM) mechanical quantum by obtained was (NIPAM-co-MA) anhydride isopropylacrylamide-co-maleic modeling on small structural units of the polymers as well as MD simulations at LCST and above the polymer based MI the that showed models QM The polymers. the of model oligomer 50-unit LCSTon was more inclined towards bend results structure, The higher polymer. hydration, based MA and the of higher those to intramolecular compared when hydrogen units monomer its between formation bond of formation the showed it as results QM the of support complete in was simulation MD scale large the of ( NIPAM-co-MA than NIPAM-co-MI hydrated highly and folded more a (vi) Multiple hydrogen bonds: polyhydroxy systems were estimated using an isodesmic/homodesmic reaction approach as well as a approach reaction isodesmic/homodesmic the that shown was It (MTA). approach tailoring molecular energy strain of effect the included but energy H-bond true give not did literature the in advocated as method. MTA the in for accounted duly was strain ring a Such structure. ring a of formation the to due Using the decitol molecule, it was shown that the MTA method was able to predict not only the H- bond energies but also the trends in conformational energies ( CH… and CH…O (vii) using DFT and semiempirical PM3 methods. The caclulations showed that the guest molecule ethylacetate molecule guest the that showed caclulations The methods. PM3 semiempirical and DFT using was trapped inside an aromatic pocket due to multiple CH…O and CH… NATIONAL INSTITUTE OF INTERDISCIPLINARY SCIENCE & TECHNOLOGY Thiruvananthapuram 92 92 of appropriatelysubstituteddibenzobarrelenes( photochromism the in biradical triplet long-lived a of intervention the supported strongly results The nm. 700 at peak absorption observed the with agreement good in was which nm, 670 at maximum biradical intermediate. The absorption spectrum of the triplet biradical, displayed an intense absorption intersystem crossing to its triplet state, followed by intramolecular rapid undergoes dibenzobarrelne of state singlet excited the that supported strongly study The dibenzobarrelne: of Photochemistry (x) K, L,MandNregionsofPAH Stereolelectronic profilephosphine ligands HIV protease-inhibitorcomplexes Process Engineering&EnvironmentalTechnology utpehdoe od ndctlCH.. Multiple hydrogenbondsindecitol This was investigated using time dependent DFT methods. DFT dependent time using investigated was This J. Am.Chem.Soc Model forDNAmetal-ioninteractions Photochemistry ofdibenzobarrelne . δ 2007 -H abstraction, to yield the triplet , 129 π host-guest complexation andCH...Ointeractionson , 9439). ANNUAL REPORT 2007-2008 93 93 anic Pollutants (POPs) and (POPs) Pollutants anic to chemicals is hampered to by exposed are people chemicals what of our understanding inadequate and to what degree these exposures might cause short effects. health adverse (chronic) term long or (acute) term The institute provides accurate, relevant and timely Org Persistent of measurements their precursors, conduct scientific and engineering India’s support to base knowledge develop and evaluations for the protection of public health. programme POPs Process Engineering & Environmental Technology Environmental & Engineering Process , in ” was organized at Sample 1 Sample 2 specialists. 22th October 2007 Solid Waste Management Waste Solid Dioxins and Furans in flue gas collected from a waste gas thermal Oxidiser plant in india Dioxins and Furans In a few short decades, dioxins have spread throughout the environment to threaten human A consultancy project for Gujarat Fluorochemicals Ltd for assessing the dioxin emission from management and dioxin control NIIST on municipal authorities, solid waste Japan. The seminar brought together A seminar “ and Dioxin Control association with OECC, Hiyoshi and ILEC, association with OECC, Hiyoshi and 3. DIOXIN RESEARCH 3. DIOXIN and environmental health all over the world. Studies show that, every living organism on earth now exposure from effects health real the assess to need The body. its in dioxins of levels measurable carries was completed. An umbrella agreement with Hiyoshi Corporation, waste gas thermal oxidation plant during signed was POPS of area the in expertise of exchange and research joint out carrying for Japan National of Development on project the implementing for UNIDO with agreement an Signed year. the Organic Persistent on Convention Stockholm the implement to step first as India in Plan Implementation Project (POPs). Pollutants is funded by and UNEP-GEF scope of the project is to prepare inventory on India. of states southern five in POPs produced unintentionally of sources industrial non and industrial NATIONAL INSTITUTE OF INTERDISCIPLINARY SCIENCE & TECHNOLOGY Thiruvananthapuram 94 94 negligible. Thepresenceof sulphide wasprominentintherettingwater(upto levelof58mgL L mg 2000 to 200 between was sites retting at water the of COD studied to assess the impact of retting pollution which include on site and sample analysis in the laboratory.were sites dozen a than More fisheries. and tourism for value potential its degrading backwaters, the of lakes backwater in pollutiontoretting due coir of Assessment ready forcommercialinstallation. is process This properties. surface and spinability fibre), processed conventionally for N 260 against extracted byclosedrettingwassuperiortoconventionalfibreintermsofstrength(380Natbreakas fibre The husk. coconut of ton per litres 50,000 average was production Biogas quality. product and operation of reliability establish to batches several through operated was plant pilot The batch. per fibre cleaner in the laboratory campus. The pilot plant was designed to process 0.5 ton coconut husk comprises a 10 M which plant pilot a up setting by scale bigger a in studied further was pollution without month one of span time a within fibre quality produce to developed reactors anaerobic a using method retting ranging from 6 to 12 months in water bodies causing severe water and air pollution. The clean closed period a for (retting) husks the of decay to subjecting by husks coconut fresh from extracted is fibre ibre f coir of extraction the for retting Closed 4. ENVIRONMENTAL TECHNOLOGY The conventional method of coconut husk retting for producing coir fibre causes extensive pollution Quality coir fibre is essential for the manufacture of a variety of coir products. Usually quality 3 anaerobic UASB reactor, 10 soak tanks of 2 M Process Engineering&EnvironmentalTechnology 3 -1 each, a coconut husk crusher and a , and dissolved oxygen content was content oxygen dissolved and , -1 ). ANNUAL REPORT 2007-2008 ) 2 95 95 ). The abundantly -1 ). In the control sites, these metals these sites, control the In ). -1 ) and crustacean species (62 no/m 2 ), snails (979 no/m Sewage treatment device HSD installed at an apartmentment 2 ), lead (up to 77 mg.kg 77 to (up lead ), -1 Process Engineering & Environmental Technology Environmental & Engineering Process . Cadmium, however, was low (max. 5mg kg -1 ), zinc (above 100 mg kg mg 100 (above zinc ), -1 This project aims at the development of a “Household Sanitation Device” (HSD) suitable for The seafood processing industries include strings of pre-processing and processing units which units processing and pre-processing of strings include industries processing seafood The Retting area sediments are marked by high concentration of heavy metals - copper (between100 copper - metals heavy of concentration high by marked are sediments area Retting areas. found benthic aerobic mollusks (354 no/m sewageHousehold treatment device devices. tank septic conventional the replace to indented and treatment sewage decentralized complete anaerobic stage two a has device The digestion system for both black and grey water. It has a settler for retention of solids and provision for gas collection. The HSD was fabricated in FRP and now installed in one of NIIST quarters continuous testing. for The effluent is COD, pH, for monitored continuously TSS, TDS. The effluent meets the coastal marine in standards discharge pollute the long coastal belt of the country. An important issue in the anaerobic treatment of seafood of treatment anaerobic the in issue important An country. the of belt coastal long the pollute solids & fats separating for method biological A fats. and solids of removal the is wastewater industry the mainly leaves It gases. generated anerobically using solids and fats out floating by wastewaters in dissolved impurities which are easily treated (95% COD removal) in the laboratory level anaerobic was filed for the method and device for separation of fats & suspended A patent application reactor. solids from wastewater. Anaerobic treatment for wastewater processing seafood and 400 mg kg mg 400 and were always less than 10 mg kg present in the control sites were totally absent in the organic rich sediments. Absence of fishes was retting areas. also noticed in the NATIONAL INSTITUTE OF INTERDISCIPLINARY SCIENCE & TECHNOLOGY Thiruvananthapuram 96 96 ra bde ad lis mjr oto o te xedtr. Wnrw opsig, n aerobic an composting”, “Windrow expenditure. the of portion major a claims and bodies urban wastes solid of treatment for technology bedLeach Anaerobic the pilottests. kg COD/m apprearance) between the successive batches was unaffected in blind tests. UASB loading rate up to 8 recycled for parboiling and 12 successive batches of paddy were evaluated. Rice quality (taste, odour, was effluent The recycle. for sufficient which effluent, of m contact, for reuse. The UASB reactor produces 1.5 m specially designed UASB can store treated water without air The reactor. UASB and exchanger heat tank, parboiling tonne/batch Pavizham2 a has plant The RiceMillinKalady. pilot plant was set up by Kalady Rice Mill Consortium Ltd., at zero-discharge A quality. rice of evaluation and conditions anaerobic under pollutants the of degradation conditions, parboiling paddy the on based constituents biological and chemical its for water involved soak the Study of characterization rice. the of quality the affecting without treatment anaerobic after recycled fully be can water soak that showed studies laboratory The treatment. anaerobic after recycled be can effluent the that found effluent was adopted for removal of the COD content. It was compounds whicharerecalcitrant(difficulttodegrade). quickly becomes putrefied and effluent is a serious environmental concern parboil with the formation of polyphenolic Untreated effluent. as discharged is water soak t 0.8 about and processed paddy eating quality (less stickiness). The hot soak parboiling process requires about 1 tonne of water/ton of and reduces insect infestation while improving nutrient contents and enhances the cooking as well as parboilingpaddy discharge for process Zero 3 effluent. This corresponds to 3 kg COD removal per litre per removal COD kg 3 to corresponds This effluent. The management of Municipal Solid Wastes (MSW) is the single biggest issue engaging the engaging issue biggest single the is (MSW) Wastes Solid Municipal of management The zero-discharge process was developed for parboiled rice mills. Anaerobic treatment of parboil Rice, a staple food of this region, is consumed in parboiled form which reduces grain breakage 3 active-volume/d was obtained in the pilot plant trials. A full scale unit is planned based on Process Engineering&EnvironmentalTechnology 3 biogas/ UASB reactorforparboileffluenttreatment pilot plant ANNUAL REPORT 2007-2008 97 97 Clear zone indicating Triclosan on Triclosan added agar medium on Triclosan degradation by bacteria growing Process Engineering & Environmental Technology Environmental & Engineering Process Excess use of antimicrobial compounds (eg: Triclosan, Tricarbon Triclosan, (eg: compounds antimicrobial of use Excess Anaerobic digestion for stabilization of putrescible fraction of MSW overcomes the above sufficient was time retention ALBR days 5 that found was it level, 5kg at studies laboratory the In A proposal for a pilot cum demonstration plant prepared and submitted to the Ministry for Biodegradation of Antimicrobial compounds to lead etc) cosmetics, detergents, (soaps, products household in etc.) the with interfere and bacteria resistant antibiotic of development the normal micro-flora in natural environments. Also, the presence of The potential. reuse its reduces water treated in compounds antibiotic environmental effects of these xenobiotic compounds are yet to be elucidated. The ongoing research funded by International Foundation biological treatment system, is usually chosen for the MSW treatment. This system has many limitations many has system This treatment. MSW the for chosen usually is system, treatment biological such as extreme odour, fly nuisance, exposure of workers to unhygienic work environment, severe recovered compost, etc. from dumped rejects, low price for leachate pollution limitations of biological treatment. The anaerobic leach bed reactor (ALBR) is formed by dumping of Volatile reactor. UASB a through circulated liquor in soaked and tank a into wastes shredded coarsely converts reactor UASB The ALBR. the in wastes organic of decay rapid during formed are (VFA) acids fatty pH. because odorous gases dissolve in the leachate which is at neutral to biogas. Odour is avoided VFA emission the causes that windrow a in as temperature high develop not does bed leach the Furthermore, Covering the leach tank restricts the entry of insects. of odour because of natural convection. for complete hydrolysis of putrescibles. from The 1 maximum kg rate unsorted of generation of VFA proportionate with waste food 25% containing MSW average for day per m.moles 200 found was MSW unsorted Kg(wet) L/ 40 was generation biogas Total fraction. waste food additional every for increase concentration allowable the within well were effluent reactor anaerobic the of pH and Alkalinity MSW. no with batch after batch re-circulated be can liquor same The ALBR. in generation leachate further for to 50 % after 5 of waste reduced No chemicals are required for pH control. Volume toxicity to UASB. order the in be will reduction volume the then %, 50 of is waste food of quantity the If leaching. day’s of 65% after 5 days. The stability of the leach bed treated MSW was tested by measuring oxygen consumption rate with a specially developed respirometer. Renewable Energy. NATIONAL INSTITUTE OF INTERDISCIPLINARY SCIENCE & TECHNOLOGY Thiruvananthapuram 98 98 production andalsoasignificant reductioninmixedliquorsuspendedsolids(MLSS). populations intracellular. Studies have revealed a high correlation between ciliate count and methane of the overall performance of a bioreactor.a of performance overall the of especially for particulate COD containing wastewater. Some of these organisms were direct indication worms, etc.) were studied for their ecological niche and functional importance in overall waste treatment organismsbioreactors anaerobic in trophic Higher approach aremorereliableandconvenient. based dye fluorescent methods culture plate conventional the to Compared samples. environmental various in count cell live/dead the about information provided Iodide Propidium and DAPI like dyes of methanogenic microorganisms in anaerobic marine sediments. Differential staining with fluorescent dynamics. rRNA based whole cell Fluorescent In-situ Hybridization (FISH) analysis revealed the presence and structure community microbial the about information valuable generate samples environmental markers molecular with analysis Microbial to analyzethemicrobialcommunitiesinvolved. compounds, analysisofthedegradationproducts,elucidationprobablepathwayand antimicrobial of biodegradation on focus lab technology Environmental in (Sweden) Science for FISH imageofMethaneproducingArchaea Anaerobic protozoa (mainly ciliates and flagellates) micro-metazoa (rotifers, dipteral larvae, dipteral (rotifers, micro-metazoa flagellates) and ciliates (mainly protozoa Anaerobic and bioreactors treating wastewater in analysis microbial targeted DNA and rRNA 16S Process Engineering&EnvironmentalTechnology C iliate such as such iliate Epi-fluorescent microscopicimageofDAPI Metopus stained microbialcells keeps methanogenic microbial methanogenic keeps ANNUAL REPORT 2007-2008 99 99 as per MOEF guidelines. Major anaerobic sludge floc Keeping in view of the proposed location, proposed the of view in Keeping Bright field image of anaerobic ciliates grazing over Bright field image of anaerobic ciliates grazing Process Engineering & Environmental Technology & Environmental Engineering Process ted the baseline data based on which the implications of the possible impacts were assessed and assessed were impacts possible the of implications the which on based data baseline the ted Completed a field survey & site selection for the proposed berth based on environmental Detailed marine ecological survey was conducted to establish the existing status of the marine the of status existing the establish to conducted was survey ecological marine Detailed Prepared an environmental appraisal report on the two proposed bauxite mining areas at A Rapid Environmental Assessment was carried out for the proposed Kaolin processing plant intracellular methane producing Archaea Phase contrast image of Metopus harbouring Kinfra Industrial park for M/s Ashapura Minechem Ltd, Mumbai sensitivity of Pawas Bay for Finolex Ltd, Ratnagiri, Maharashtra. Ratnagiri, Ltd, Finolex for Bay Pawas of sensitivity water around three proposed project sites for M/s Mumbai biological and Port Pwer physicochemical Tata Trust, of Corporation analysis and and collection data included study The Fisheries. Mirkarwada analysis, detailed for samples mangrove of collection samples, sediment and marine of characteristics enquiry with fisheries department and local fishermen as per MOEF guidelines. mitigation measures recommended. Battelle environmental system was used for evaluation of impacts. to quantitatively predict the impacts on air and water quality. Mathematical models have been used impacts on the environment due to dust emission, traffic, consumption of water and rejects management rejects and water of consumption traffic, emission, dust to due environment the on impacts were documented in the report. Existing environmental data with respect to the above parameters constitu the navigational channel, shallow and deep regions, point of inflow, outflow and and human site activities, project proposed the around and in locations four at done were sampling sediment and water and reported. their physical, chemical and biological diversity characteristics were analyzed Thiruvananthapuram. Geology, & Mining of Directorate for district panchayat,Kasargod block Manjeswar deposit details, drainage and This study included data collection, analysis of the reports on Geology, hydrogeology contributed from DMG, observations made directly, and possible significant impacts assessed and mitigation measures.. at Environmental Management Services NATIONAL INSTITUTE OF INTERDISCIPLINARY SCIENCE & TECHNOLOGY Thiruvananthapuram 100 100 .Agreement for licensing of know-how for making white pepper from dried pepper (black) 8. and matured Agreement for technology transfer and licensing of knowhow for setting up of an integrated spice 7. Agreement for licensing of technology for processing fresh spices with Arunachal Agri-Biotech Pvt. 6. Community with Mizoram in spices fresh processing for technology of licensing for Agreement 5. .Agreement for licensing of know-how 4. Agreement for utilizing the know-how developed by NIIST in the treatment of rice parboiling soak 3. Kerala in (FSC) Centre Service Farmers up setting for Plan Business a developing for Agreement 2. 13. Consultancy agreement Consultancy 13. Memorandum of agreement for 12. Scale-up studies on the production, characterization and application Consultancy agreement for restructuring the on-going training and training material for technical 11. Agreement for Development and 10. evaluation of techno-economics through pilot scale demonstration Agreement for Research on application of colloidal processing techniques for improving the performance 9. work: Consultancy and takingR&D for signed Agreements Assignment deed 1. and TechnologyLicensing Transferagreements: Agreements/MoUs signedduring2007-08 RESEARCH PLANNING ANDBUSINESSDEVELOPMENT RESEARCH PLANNING with M/sThermaxLtd.,Chinchwad, Pune–411019. conbustion system: computer aided process modeling, optimisation and material characterization” of cold active beta-galactosidases - a therapeutic agent for lactose intolerance with DBT, New Delhi. New Delhi–110003. Road, Lodhi Institute, Resources and Energy The with Pradesh Uttar East Trenchin Bulls kilns on programmes underthecosmilebrickprojectforcapacity buildingoffiremencommunityworking and Technology PromotionCouncil(BMTPC),LodhiRoad,NewDelhi–110003. Materials Building with Ash Fly bonded flux volume high from materials building added value of of advancedceramicmaterialswithM/sCromptonGreavesLtd.,Worli, Mumbai400030. green pepperwithShri.N.S.JithendraKumar, NewJithendraTraders, Chickmanglur–577101. Government ofSikkim,KrishiBhawan,Tadong –737102,Gangtok. processing facility in the state of Sikkim with Horticulture and Cash Crops Development Department, Ltd, Itanagar, Papumpari DistrictArunachalPradesh–791111. Development Action&Reflection(CDAR),Aizwal-796001. stem andfruitbunches water inthefactoryatKaladywithM/s.RiceMillersConsortiumPvt.Ltd.(KRMCPL). with theAgricultureandOrganicFarming GroupIndia(AGFGIndia),Delhi. with NRDC for “N with , New Delhi for commercialization of 14 technologies/process know-how. Mr. R.Murugan,Coimbatore–641023,Tamil Nadu. situ CO situ on 2 Bioprocess to extract banana fibers from banana pseudo separation in energy recovery by chemical looping in looping chemical by recovery energy in separation ANNUAL REPORT 2007-2008 101 101 AGRO PROCESSING DIVISION and by productsstate of Orissain terms of phytochemical and chemical markers, chemical characteristics of bhasmas C. Arumughan Dr. C. Arumughan Dr. C. Arumughan Dr. of Down Stream products from RBO and other Oils Phase II C. Arumughan Dr. generation process and high value products from oil seeds analysis and research of persistent organic pollutants in India with HIYOSHI Omihachiman, Shiga, Japan. Corporation, 7 SAS, CORNING M/s with lenses sun-glass and ophthalmic in use for suitable dyes chromic photo 77210 Avon France. Bis avenue de Valvines, be disclosed regarding processes and know-how related to solid-state fermentation for production the of industrial enzymes” with Cover Technologies, Inc., 95 State Street, Suite Springfield, Massachusetts 01103. 812, Pittsburgh, Place, PPG One Corporation, US a Inc., Industries PPG with biodegradation to related 15272, USA. PA Thiruvananthapuram Thiruvananthapuram with Directorate of Mining and Geology under Department of Industries, Thiruvananthapuram – 4. Government of Kerala, Government Industries, of Department under Geology and Mining of Directorate with studies EIA – 4. Thiruvananthapuram of Kerala, Ernakulam District, Kerala. Kalady, a Private Limited Company STCLTMOPCSIR Ayush Setting up chilli processing plant in Karnataka FFB/hr palm oil mill in the Establishment of 2.5 Ton Standardisation of plants, plant products and formulations Sreekumar M.M. Mr. CLIENTTMOPTMOP PROJECT TITLE PROJECT LEADER TMOP Development of Supercritical Fluid Extraction for Edible oil Development of technology of refining and production C. Arumughan Dr. R&D Industry Consortia approach to develop a new Contract Research Programmes Agreements with foreign agencies: 17. Umbrella agreement on design & operation of Jokaso, river and lake restoration, measurement, develop to work Design and Development Research, Investigation, 18.on agreement work Development may that information proprietary certain of protection 19.and on”Handling agreement Non-disclosure coatings and polymers of evaluation and 20.Synthesis on agreement information/sample Confidential 14.Mangalapuram, of areas mining clay in study EIA regional conducting for agreement Consultancy 15. Agreement for mapping regions under coir retting in the coastal areas of Kerala state chosen for 16.Consortium, Millers Rice Kalady with unit refining oil bran rice a up set to agreement Consultancy NATIONAL INSTITUTE OF INTERDISCIPLINARY SCIENCE & TECHNOLOGY Thiruvananthapuram 102 102 LETPOETTTEPROJECTLEADER Design&development ofphotoinduced electron DST Designanddevelopmentofmaterials forphotonic PROJECTTITLE DST/CSIR CLIENT Dr. AshokPandey DevelopmentofthermostableandlowpHtolerantphytase DBT IsolationandcloningofglucosetolerantBeta-glucosidase Bioethanolfromlignocellulosicbiomass Constructionandscreeningofenvironmental DNA DST CSIR Production,characterizationandapplication ofmicrobial DBT Microbialmediatedremovalofironmineralimpurities DBT DST UtilisationofbrowncoirwastepithforLignindegrading Developmentofefficientprobiotictocombatvitamin MOEF MetabolicactivitiesandGeneticmanipulationleading Dr. P.DBT Prema tuberculosis Mannolipids andmannosemetabilisminmycobacterium Scaleupstudiesontheproductionofgalactosidases DBT FRENCH INDO MolecularStudiesonpeptidedeformylaseandthe DBT DBT PROJECTTITLELEADER MolecularCloningoverexpressionandBiochemical KSCSTE CLIENT riiilpooytei Dr.Das Gopi Dr. RajeevKSukumaran artificial photosynthesis transfer systemwithdendritic architecturefor Dr. AshokPandey from Aspergillusnigerusingsitedirectedmutagenesis of theenzyme Dr.SathyChandrashekar/ from Trichoderma reeseiandstudieson theproperties from fungalisolateBTCF-5 andtheCBH1controlelements Dr. AshokPandey Dr. Mrs.P. Prema libraries fornovelbeta-lactamaseinhibitorsandlipases Dr. P. Prema alpha galactosidase-Atherapeuticalenzymeforflatulence from kaolinforvalueaddition products fromfermentedwastepith enzymes productionanddevelopmentofvalueadded B12 folicacidandirondeficiency novel applications to nutraceuticalproductsfromlacticacidbacteriafor deformulase ofM.Tuberculosis H37Rv Methionine AminoPeptidase involvedinpeptide tuberculosis characterisation ofbetalactamasesMycobacterium plctosDr.Das Suresh applications CHEMICAL SCIENCES&TECHNOLOGY DIVISION BIO-TECHNOLOGY DIVISION Dr.Nampoothiri Madhavan K. Dr.Nampoothiri Madhavan K. Dr.Nampoothiri Madhavan K. Dr.Nampoothiri Madhavan K. Dr.Nampoothiri Madhavan K. Dr.Prema ANNUAL REPORT 2007-2008 103 103 Prasada Rao bioactive compounds of Njavararesins for UV curable applicationsearth based colorantsparticles(ENCP) for novel catalytic applications A. Jayalekshmi Dr. AshaKannan Dr. (Mrs) Emilia Abraham Dr. MLP Reddy Dr. extraction using tailored ion imprinted polymer materialsextraction using tailored ion imprinted Prasada Rao T. Dr. for materials from electrically conducting PANICNs space applications. J.D. Sudha Dr. processing industryDr. MLP Reddy MLP industryDr. processing warfare agentsBiomimetic sensors for detection of chemical T. Dr. pollutants in natural watersfor electronic divicesbased colorants for surface coating applications MLP Reddy Dr. Prasada Rao T. Dr. Dr (Mrs) AshaKannan molecules on meta nanoparticles & their molecularly on meta nanoparticles molecules Abraham Emilia (Mrs) TherapyDr. Gene for implication thingscarbenes and related Glyco Conjucatesbased on lanthanide complexes as value through resource recovery and its reintegration minerals added state of art products in titanium G. Vijay Nair Dr. MLP Reddy Dr. Radhakrishnan K.V. Dr. bridged arrays on surfacesbridged arrays on and Nano structured DNA;induced components George Thomas Dr. KSCSTEDMSRDE bonding Design and development of novel hydrogen IRE Synthesis of spinnable grade PBODBT secure rare Design & development of environmentally Investigations on immobilized enzyme nano AshaKannan Dr. DSTDSTSTEC. GOK Exploration of a novel reactivity of epoxides prospecting and in vitro activity evaluation of the Chemical Chandrasekhar T.K. J.C. Bose fellowship to Prof. K. Chandrasekhar T. Prof. Shanmughan Dr. DSTDSTVSSC of high resolution TEM at RRL TVM Establishment Probes based on organic ligands Development of Novel Development of EMI shielding/Static charge dissipating Ramaiah Dr. Director DSTBRNS Neutral Substrate receptors Calixpyrroles, Novel Anion and via solid phase Recovery of Uranium from Sea Water A.Srinivasan Dr. DRDO KSCSTEDST FAST Design and development of polymeric material for organic assembled Supra Molecular containing polymers Novel self KSCSTENMITLI Design and development of Novel PI conjucated material Design and development of Environmentally secure RE JayaKannan Dr. DSTDST Novel component reaction involving nucleophilic TIRUPATHI luminescent molecular devices Development of efficient Design, synthesis and biological studies of Neo MOEF Development of Novel Solid waste remediation process DST Optical & electronic studies of photoactive DSTphase of cation Investigation on the liquid crystalline NATIONAL INSTITUTE OF INTERDISCIPLINARY SCIENCE & TECHNOLOGY Thiruvananthapuram 104 104 S Design,Synthesis andCharacterisationofNovelpolysilane DST CDPreparationofnewceramic oxides& generationofXRPD Dr. ARRMenon ICDD Lightning Ltd LowlossceramicpolymercompositesforMicroelectronic Areva T&D Dr. M.T. Sebastian DevelopmentofPressuresensitiveadhesives DevelopmentofMgbasedalloysforhightemperature KSCSTE KSCSTE DST Fatigue characteristicsoflowPr. castAZ91MGAlloyDr. U.T.S. Pillai Thermal,elasticanddielectric propertiesofnew DRDO/CUSAT Microwaveceramicdielectricresonatorsbasedon Materialforwirelesscommunication DRDO KSCSTE DST DevelopmentofHTScurrentleadsasproductsforhigh Prof.T.K.Chandrashekar/ PROJECTTITLELEADER BRNS/BAR DevelopmentandDemonstration ofenvironmentally KERALA GOV CLIENT DevelopmentofSensitizersbasedonNMRDyes Studyof photoinducedelectrontransferincyclodextrin DST EngagingN-HeterocyclesandN-Heterocycliccarbenesas BRNS Dr. Jayakannan Functional hybridnanomaterialsofpolymericgelsand DST Microanalyticalinvestigationsofurinarystones: IFCPAR Dr. Ajayaghosh A. Dr. S.SureshDas Dr. AjayGhosh KSCSTE Researchprojecttodevelopsuperiorphoto-chromicdyes Functional nanomaterialsofpi-conjugatedmolecules M/s. Corning forscalability Gamble, USA PMCTransformations understanding Melt/Solutionprocessableconductingpolyanilinebased Proctor and DST Metal-coordinatedimprintedpolymersfordrug RamannafellowshiptoDr. AjayGhosh DST DST DST atrsDr. JoseJames patterns Dr. M.T. Sebastian Dr.A U.T.S. Dr. Pillai Development ofhighenergyvaristorsthroughnanoprecursors Dr. SyamaPrasad applications(Coll. withNMLJamshedpur) microwave substratematerials Dr. M.T. Sebastian AO-LE203-Ti02(A=Ca,Ba,Sr) forwirelesscommunication Dr.Gopidas Dr.current superconductingsystems WarrierKGK friendly technologiesinKerala buildingmaterial sectors Dr. G.VijayNair Dr. Ajayghosh A. Dr.R.Luxmi Verma Dr. JayaKannan based supramolecularsystems Heteroatom bondformingreactions Dr.organocatalysts forNovelcarbonand T. PrasadRao Pi conjugatedselfassemblies spectroscopyvsSEM-EDAX FTIR magnetic films delivery applications akgn plcto Dr. C.Pavithran Dr. S.K.Shukla high polymersforUVandNUVLED’sMaterials Packaging application MATERIALS ANDMINERALSDIVISION Ramaiah nanthakumar ANNUAL REPORT 2007-2008 105 105 Dr. S. K. Ghosh Dr. refrigeratorspilot scale demonstration of value added building materials from high volume flux bonded fly ashXRPD patternscomposites for nuclear applications G. K. Warrier Dr.K. Manoj Rama Verma Dr. D. Rajan P. T. Dr. Jose James Dr. ceramic surfaces plasma processingmaster alloys from sillimanite through N. Mohandas P. Dr. multifilamentary mgb2 superconducting wires composites for Ceramic-metal and polymer-metal electromechanical applicationsRendering Scientific and technical support to M/s. CMRL synthetic rutile commercial plant. U. Syamaprasad Dr. K.G.K. Warrier Dr. Jose James Dr. N. Mohandas P. Dr. applications as chemical mechanical planarisation/polishing slurry space applications circuitshigh speed communication integrated anti algal, anti size photo catalytic titanium oxide for terra cotta,glazed bacterial and anti soiling coating on Manoj Rama Varma Dr. Sri. K. Sukumaran NTC thermisters.NTC of industrially potential phosphates and development application areas applicationsfiltration ceramic membrane for industrial K. G. K. Warrier Dr. Koshy Peter Dr. K. G. K. Warrier Dr. and dielectric applicationsand dielectric Sr;B=Ti, Zr and C=V,Nb,Ta) and CA3ce3B7C2O26.5(A=Ba, cyclying for possible applications in and their thermal Koshy Peter Dr. BMTPC of techno economics through Development and evaluation ICDDDST Preparation of new cramic oxides and generation of their BRNS materials and devices microwave Tunable matrix Development of Boron carbide reinforced aluminium Jose James Dr. IRE MumbaiIRE on the production of aluminium-silicon Investigations DSTBRNS, Bombay An investigation on the technical feasibility of making long CMRL, Alwaye DRDO magnetic Development of ceramics-based nano stuctured BoardLPSC Developing of coconut climbing bikeDST characterisation of metallic materials for Metallurgical DST composite tapes for modern Nanostructured dielectric LTCC and technical feasibility of nano Pilot scale demonstration John V. Dr. ICDDIRELTDC pattern diffraction Generation of powder X-ray nanosize rare earth Pilot scale production facility for BHEL, Bangalore of multifunctional ultra Development and demonstration IRE Prabhakar Rao Mr. based nanomaterials for Development of cerium oxide KSCSTE for phosphor rare earth based phosphates Studies on novel DST A3 Ce3 B5 C5 O30 on Novel Oxide Semiconductors Studies Coconut Development NATIONAL INSTITUTE OF INTERDISCIPLINARY SCIENCE & TECHNOLOGY Thiruvananthapuram 106 106 CP Value addition ofIndianChinaclayandoptimumutilisation KCCPL Nucleation,movement andgrowthofgasbubblesin Anaerobic degradationofperchlorateanddevelopment Motors Ltd. M/s. General Development ofamolecularaggregationmodelforthe Mr.DBT P. Raghavan Rationaldiscoveryofnovelphotoresponsivemoleculesand DST BiodegradationofTriclosan underaerobicandanaerobic Evaluationforthebeneficiabilityofsilicasand DST GMDCSRC Dr. P.P. Investigationsonlayerbyvapourphasecoating Thomas IFS Dr.(Mrs). QuantumchemicalandQSARstudiesoncarcinogenic ElizabethJacob DST Dr. RoschenSasikumar DST Pilotplantforecofriendlycoirrettingandwastewater DevelopmentofballcopraNCDriers Simulationbaseddesignofrigging system MOEF PredictionofsolidMorphologyinMushyalloys CSIR ARDB TITLEPROJECTLEADER PROJECT DevelopmentofmodularHSDforDeneutralisedsewage DMRL MOEF CLIENT GenerationofpowderX-ray difractionpatternsfornew Developmentofultrafinegrainaluminiumalloyand ICDD Investigationonthereactivityandwettingbehaviour ISRO BRNS PROCESS ENGINEERING&ENVIRONMENTAL TECHNOLOGY DIVISION anrMr. P. Raghavan Dr. S.Savithri Dr. B.KrishnaKumar Kannur of channelwasteforM/s.KEralaclays&Ceramicproducts, Dr. B.KrishnaKumar Dr. K.P. Vijayalakshmi a bioprocessforremovingperchlorateinaqueousphase Dr. V. B.Manilal ceramic nanoparticles co precipitationsynthesisofBa(Mg1/3Ta2/3)O3 dielectric Dr. C.H.Suresh Mrs.AniK.John materials: molecularmodeling,simulationsandsynthesis Mr. J.Ansari conditions oxidic microparticlesinafluidizedbed. epoxide derivatives activities ofpolycyclicaromatichydrocarbonsandtheir of pollution treatment undertheschemeforassistanceofabatement Dr. T. P. D.Rajan Dr. PrabhakarRao treatment Dr.WarrierKGK generation ceramicoxidecompounds for spaceapplications composite throughequalchannelangularpressing(ECAP) sintered ceramicandcoatings of moltenmetalswithnanosizelanthanumphosphate lmnu atnsDr. RoschenSasikumar aluminium castings ANNUAL REPORT 2007-2008 107 107 CONSULTANCY PROGRAMMES CONSULTANCY looping computer aided process modeling S. Savithri Dr. to M/s Terra Tile Consortium Ltd.to M/s Terra phosphates production for nanosized rare earth for M/s IRE Ltd. K. G. K. Warrier Dr. K. G. K. Warrier Dr. Consultancy for spice processing unit at Sikkim Sri. M.M. Sreekumar on coconut husk retting consortium for application in to develop an anaerobic waste water treatment Manilal V.B. Dr. Manilal V.B. Dr. a bioprocess for removing perchlorate in aqueous phase in aqueous for removing perchlorate a bioprocess B. Krishna Kumar Dr. rtment, New Delhi BHEL,BangaloreThermax Ltd for the fabrication of SiC filter Development of Gel casting direct coagulation method In situ CO2 separation in energy reovery by chemical DIR Miningand Geologyof Mangalapuram EIA study in clay mining areas C. Pavithran Dr. J. Ansar Mr. Tata EnergyA report on raw materials and processing of clays for Ltd. EnergyA report on raw materials and processing of clays Tata and Resource quality building productsInstitute, K. G. K. Warrier Dr. IREBHEL, Engineering consultancy to the setting up of a pilot scale BangaloreAstra Zeneca carbide hot gas filtration comps. silicon XRD method for quality control drugs Consultancy for sol-gel mullite mullite coatings on porous Pharma India K. G. K. Warrier Dr. U. Syamaprasad Dr. Ltd. Pune Palm-Colgate on the production of amino acids, Literature survey olive, USA TileTerra especially glutamic acid, arginine and citrulline support Consultancy & Technical Ashok Pandey Dr. Hort. & Cash Crop Dev. Depa Govt of Sikkim Bio-Hitech sciences India of Microbial strains for the Isolation and evaluation production of nitrilase, reductase and hydantoinase Ashok Pandey Dr. Oils Pvt Ltd.mills at Orissa Consultancy on establishment of palm oil Kaladi RiceConso-Millers plant for for M/s Rice Millers Consortium, Kerala. refinery of rice bran oil Consultancy for the establishment C. Arumughan Dr. rtium, Kaladi A. Sundereshan Dr. DBT effort marine sediments with special Microbial analysis of CLIENTSTCLLakshmi Balaji PROJECT TITLE Consultancy for chilli processing plant in Karnataka Sri. M. M. Sreekumar PROJECT LEADER DBT of degradation of perchlorate and development Anaerobic ICAR technology cum demonstration of Pilot project on research NATIONAL INSTITUTE OF INTERDISCIPLINARY SCIENCE & TECHNOLOGY Thiruvananthapuram 108 108 Patents granted (India) 1571/320 rcs o h rprto fanwMailadilThomasSebastain Aprocessfor thepreparationofanew 14/03/2008 216517 DasS,ThomasKG,BijuVP, JacobKoshy, JoseKurian, NovelceremicsubstrateBAZDYMO S:S 18/02/2008 214935 Squarainebaseddyes 27/12/2007 213357 HariharaIyer, Aprocessforthepreparationofanovelceramic 17/01/2008 213822 1211/320 nipoe rcs o h ytei f44 MLalitambika,Rugmini Animproved processforthesynthesisof4,4- 11/03/2008 216251 JohnVerghese, Ballembettu Aprocessfor themanufactureofanaluminium 28/02/2008 215620 ChennakkattuKrishna Aprocessforthepreparationofaqueous Pokkattu 27/02/2008 Pathrose Thomas, 215578 Animproveddrierusefulforprocessing 21/02/2008 215126 Sreedhara N Anovelprocessforthemanufactureofsuperior 14/11/2007 197050 R I td o R Mr. J.Ansari Dr. Savithri S. EIAstudyforIRE CoalcombustionmodelforlowNOxburnerswallfired andcorneredfiredcoalboilers Industries Ltd. Mechwell IRE eiaie KRSabu BaO-Nb2O5-TiO2 system microwave ceramicdielectricresonatorinthe derivatives Poo Kodan Sajith,Krishnan RaveendranRatheesh, (M=ZR,SN &HE) Sreemoolanathan, applications material usefulformicrowaveintegratedcircuit fraction imn ihnlMtaeadissbtttdSukumaran,DBahulayanand NairDevakiamma Sudha, Diamino DiphenylMethaneanditssubstituted ChandrasekharPai, conductor alloywithimprovedconductivity ThiruthanathilPathrose SadasivanPillai,Janardanan cardanol basedresins emulsion fromcashewnutshelfliquid/ agricultural products coconut, whitecopralauricoilandproteinrich speciality coconutproductssuchassnow-white PATENTS Sonthosh U,SureshV Pezholil Mohanan Asha MaryJohn,Alathur Sudersan Kumar, RajanJose, Mailadil ThomasSebastain, Shaji, RamanMarimuthuPillai Padmanabhan Anandan Narayanan Sudhilal Damodaran Damodaran Muttathupara Chellappan Sivankutty NairPrasad, Vadakkethonippurathu Poulose, PunathilBalan, ANNUAL REPORT 2007-2008 109 109 Kavithaa S, Pai BC, Pillai RM, Kavithaa S, Pai Vakayil K Praveen Vakayil 3 O 2 (M=Y,Rare Earth MetalEarth (M=Y,Rare Jose James, Selvaraj MetalEarth (M=Y,Rare Jose James, Selvaraj 6+x 6+x , MM’O , MM’O , 2 2 preparation thereof process thereoffor use as reinforcements in al MMCs Satyanarayana KG, Banerjee S separation and refining of plant materials Manilal, Ajit Hardas Chakkooth Vijayakumar, resourcespreparation super hydrophobic coatingand a process for the preparation thereof Sampath Srinivasan, K Pravin Vakayil powder for selective detection ofzinc ions and a process for the Sivaramapanicker Sreejith Arimboor Ranjith a process thereof and their preparation as nano particles K.Oonnikrishnan Nair titanium dioxide particle through vapour phase hydrolysis of titanium tetra-chloride and M-=Sn or Zr) dielectric ceramicsand their preparation as nano particles Senthilkumar and K.Oonnikrishnan Nair 4-Benzoquinoneof 2, 5- Dihydroxy-1, derivatives like Embelin from natural Nuyampaditharayil Madhavan Soumya, useful for household laundry drying Thir preconcentration of Erbium ions and Prasada Rao Naphthalenenonlinear optical crystal fromtitanyl phosphate fluoride phosphate solution potassium sodium Sebastian M T Sadasivan Pillai processable liquid crystalline Poly (4-Phenylene Poly liquid crystalline processable -CO-8-2,6-Carboxylate Naphthalene Vadakkethonippurathu 2-Methoxy -(4-Polyphenylene, |(S-Oxypheny)s Chennakkattu Krishna Sivankutty Nair Prasad, (CN)(KR) and M-=Sn or Zr) dielectric ceramicsand Senthilkumar of ultra-fine rutile phase synthesis K.R. Prasad and S. Savithri (CN)(GB) useful for household laundry drying Thir particles for solid phase extractive Gladis Joseph, Talasila 2749DEL2007 28/12/2007 White light emitting Organogel and Ayyappanpillai Ayajaghosh, 0525DEL2008 05/03/2008 A method for anaerobic process coupled Balakrishnan Vattackatt 1974DEL2007 18/09/2007 Nanocomposite material useful for the Ajayaghosh, Ayyappanpillai 2748DEL2007 28/12/2007 Pyrrole end-capped Bipyridine assay Ayyapanpillai Ajayaghosh, 0370DEL2008 12/02/2008 Stable oxide coating on SiCp,Cr and Al 1711DEL2007 10/08/2007 An improved process for the isolation Chami Arumughan, ZL03826256.8 14/11/2007 Mg 10-0800129 25/01/2008 A Novel low temperature glasses for the K.S. Anie, G.D. Surender, 7347983(US) 25/03/2008 Mg filed (India) Patents 723992(KR) 25/05/2007 An improved natural convection drier Thomas, Pathrose Pokkattu ZL01823130.6 16/05/2007 convection drier An improved natural Thomas, Pathrose Pokkattu GB2424893 25/07/2007 Synthesis of ion imprinted polymer Kala Ramakrishnan, Mary 217730 28/03/2008process for the preparation of potassium A Suma S, Santha N I, 216824 19/03/2008 of melt A process for the preparation Vijayanathan, Veena Patents granted (Foreign) granted Patents NATIONAL INSTITUTE OF INTERDISCIPLINARY SCIENCE & TECHNOLOGY Thiruvananthapuram 110 110 W)ai ne oi tt emnainSinghSudheer Kumar, Singhal acidundersolidstatefermentation SaudagarParag Subhash, Fermentive productionofclavulanic (WO) 27/04/2007 PCT/IB07/001095 Patents filed(Foreign) 9/08P)1/320 oe cnmccladefcetChamiArumugham, ChandrasekharanPillai processforcommercialproductionof Anoveleconomicicalandefficient 18/03/2008 295/2008(PK) ChamiArumugham, Anoveleconomicalandefficient (WO) 07/03/2008 Padala PrabhakarRao, PCT/IN08/00143 Mundlapudi Lakshmipathi Developmentofyellowpigments 25/02/2008 12/036848(US) Padala PrabhakarRao, comprisingalkalineearth, Developmentofyellowpigments Padala PrabhakarRao, 22/02/2008 2008-041921(JP) Developmentofyellowpigments 21/02/2008 0851116(FR) Padala PrabhakarRao, Developmentofyellowpigments (CN) 19/02/2008 0278NF2006/CN odtosuigar-nutilRekhaSatishchandra, conditions usingagro-industrial oxides andprocessthereof oxides andprocessthereof Pandey Ashok oxides andprocessthereof oxides andprocessthereof residues ihprt inn rmssm i Balachandran,MullanVelandy high puritylignansfromsesameoil ChandrasekharanPillai process forcommercialproductionof Balachandran,MullanVelandy high puritylignansfromsesameoil MundlapudiLakshmipathi Reddy praseodymium andtransitionmetal MundlapudiLakshmipathi comprising alkalineearth, Reddy praseodymium andtransitionmetal MundlapudiLakshmipathi comprising alkalineearth, Reddy praseodymium andtransitionmetal comprising alkalineearth, Reddy praseodymium andtransitionmetal Kumari SathyanandanSaritha Kumari SathyanandanSaritha Divya Sukumar, Syamala Sundaresan, ShinyThomas, Reshma, Andikannu Divya Sukumar, Syamala Sundaresan, ShinyThomas, Reshma, Andikannu ANNUAL REPORT 2007-2008 111 111 e-Journals LIBRARY & INFORMATICS LIBRARY Sage * Indian Jls.com of Divan Enterprises * Royal Society of Chemistry Springer/ Kluwer & Francis Taylor Wiley Interscience Nature * Blackwell Cambridge University Press Elsevier (Science Direct) Emerald IEEE Oxford University Press American Chemical Society z z z z z z z z z z z z z z Trial Trial access followed by regular access to the e-resources under the CSIR Updated the in-house databases of Books, Periodicals, Reports/Reprints, PhD Theses, Publications Theses, PhD Reports/Reprints, Periodicals, Books, of databases in-house the Updated The total collection has gone up to 40,000 plus documents which include 12,258 Books, The year 2007-08 was a period of major accomplishments for the Library & Informatics e-Resources Access Facility under the CSIR Consortia Programme. e-Resources Access Facility under through the desktops of all scientists, research students Consortia Programme was facilitated publishers facilities/ access of list The mode. enabled IP- in Lab the across functionaries other and whose e-journals full text databases are accessible is furnished below ( * during the year of reporting) : indicates new additions of NIIST Scientists, etc. The last two databases were up-linked to the Intranet.Conducted regular Lab’s and extensive CD-ROM Website and Online database as searches including those well of as Standards and Patents. Databases and Database Searches 10947 Standards and 8019 Bound Volumes of Periodicals. The total number of the print versions of versions print the of number total The Periodicals. of Volumes Bound 8019 and Standards 10947 -10) Gratis & 82 – Indian 82, - Foreign : (Subscribed Titles 174 was year the during received periodicals Information Resource Management Collection Strength department with immediate impact and beneficial changes for the long run. The overriding goal of the of goal overriding The run. long the for changes beneficial and impact immediate with department library has been to provide the best network based services possible to the S & T Community. The section made significant progress in creating and further strengthening the infrastructure, resources include: Highlights of the achievements and rendering services. NATIONAL INSTITUTE OF INTERDISCIPLINARY SCIENCE & TECHNOLOGY Thiruvananthapuram 112 112 lab, NewsPaper Clippingsetc. Annual Reports, Thesis, Audio and Video Clippings of major Programmes and Conferences held at our Repository Institutional New barcodedmembershipcardsgettingreadyfor issue. been automated using Libsuite - Integrated Library Software. Completed Barcoding of Library documents. & WebAutomation Library OPAC Web ofScience,ScienceCitationIndexExpanded. journals for which no IF is furnished in JCR Science edition 2006, even though the titles are covered in gone up to 204 with an average IF value of 2.57. The total no. is excluding 6 papers published in new Factor.Impact high with Papersjournals SCI in has publishing of (2007) for number service total The support Provided SCOPUS. and Expanded Index Citation Science - Science of Web Report, Citation Publications of Analysis research, industrialandacademicsectors. Initiation ofnewmemberstothevariousservicesLibrary&Informatics - - andBISonline ASTMStandardsonCD-ROM e-Resources promotionalactivitiesundertakentoenhanceusage - programmes haveenhancedthelevelofusage. Delphion&DerwentInnovationsIndex promotional various and usage of monitoring regular The SCOPUS). and Direct (Science Elsevier and - e- ResourceAccessfacilitiesarrangedundertheLabFunds: Digital Library Web ofScience–CitationIndex Standards Patent Databases - Bibliographic &CitationDatabases racse rglr esgs f e fclte/ evcs ntae ad otd h sm i the in intranet withsearchlinkstoeachitem same the hosted and initiated services facilities/ new of messages regular Broadcasted Steps have already been initiated to create an Institutional Repository of NIIST Publications, NIIST of Repository Institutional an create to initiated been already have Steps have System Circulation the including services and activities in-house Library the of Majority Carried out Bibliometric/Scientometric/Impact Factor Analysis of NIIST Publications using Journal from primarily users, external to extended were services and facilities resource addition, In SCOPUS of Elsevier: The usage of e-resources has been overwhelming particularly those of ACS This wasinadditiontotheTrial accessofScienceDirecte-Books,ASTMStandardsand Expanded ANNUAL REPORT 2007-2008 113 113 - First phase implemented successfully - Second phase in progress - Cyber Security (implemented / nearing completion) Total - Storage Devices (implemented) - the process of implementation) (in Facility Video Conferencing - – implemented Wi-Fi System Facility - of PCs and addition of new devices (ongoing) Up gradation LAN/WAN segments of the 24x7 Network System Facility segments of the 24x7 Network LAN/WAN Air-conditioning Air-conditioning of L & I completed. Action initiated for total modification of interiors and Commenced Physical Verification of Library Books & Periodicals. Binding of back volumes of * leased line of BSNL 2 Mbps of implementation) * Alternate Leased Line (in the process * E-mail & Messaging System * Goa MIS with the tie up of NIO, * Implementation (ICT) Programme Information Communication Technology *through Officers Technical & Scientists all of desktops the to Connectivity Internet Speed High IT-Enabled Systems and ServicesIT-Enabled creation of additional access facilities for achieving better ambience, comfortable reading environment reading comfortable ambience, better achieving for facilities access additional of creation to users. and more facilities Better PhysicalBetter Ambience & Facilities periodicals and Books are in progress. periodicals and Books Physical Physical Verif ication & Binding NATIONAL INSTITUTE OF INTERDISCIPLINARY SCIENCE & TECHNOLOGY Thiruvananthapuram 114 114 AJAYAGHOSH (A),PRAVEEN (V K), SRINIVASAN (S)andREJI VARGHESE 9 8AJAYAGHOSH (A),CHITRA(P)andREJIVARGHESE AJAYAGHOSH (A)andPRAVEEN (VK) 7 ABHILASHKUMAR (RG),VINOD(K),VARGHESE (N)andSYAMAPRASAD (U) 6 ABHILASHKUMAR (RG),VINOD(K)andSYAMAPRASAD (U) 5 ABHILASH(NP),DEVI(BR),SURESH (E)andVIJAY NAIR(G) 4 ABDULKHALAM(L),SHERINTHOMASandSEBASTIAN(MT) 3 ABDULKHALAM(L),SHERINTHOMASandSEBASTIAN (MT) 2 ABDULKHALAM(L)andSEBASTIAN(MT) 1 Description No Sl SCI Titles 4(4):359-366;Aug 2007 International JournalofAppliedCeramicTechnology 19(3):411-415;Feb 2007 19(3):411-415;Feb Materials Advanced Oligo( Quadrupolar 46(1-2):230-233;Jan 2007 Angewandte ChemieInternationalEd and changefromsphericaltohelicalmorphology Self-assembly ofTripodal squaraines:Cation-assistedexpressionofmolecularchirality 40(8):644-656:21 Aug2007 Accounts ofChemicalResearch size, shape,andfunctions π 2007 20(3):222-227;March Superconductor ScienceandTechnology Reactivity ofsheathmaterialswithMg/BinMgB 88(2):243-247;Aug 2007 MaterialsScienceandProcessing Applied PhysicsA: Preparation ofMgB 48(25):4391-4393;18 Jun2007 Tetrahedron Letters derivatives An efficientmulticomponentprotocolforthestereoselectivesynthesisofoxazinobenzothiazole Tailoring themicrowavedielectricpropertiesofM 90(8):2476-2483;Aug 2007 Journal oftheAmericanCeramicSociety [B’ =Lanthanides,Y, andIn] system Temperature-stable andlow-lossdielectricsintheCa(B’ 2007 90(5):1467-1474;May Journal oftheAmericanCeramicSociety Low lossdielectricsintheCa(B’ organogelsofself-assembled p -phenylenevinylene)s π -gels: Sol-gel tunable red-green-blue emission in donor-acceptor-type LIST OFPUBLICATIONS: 2007 2 /Fe superconductor wirebyelectricalself-heating 1/2 p -phenylenevinylenes: Softmaterialswithdistinct Nb 1/2 )O 3 [B’=Lanthanides,Y]system 2 conductor fabrication conductor g Nb 2 O 6 1/2 andMg Ta 1/2 )O 4 3 Nb 2 O 9 ceramics ANNUAL REPORT 2007-2008 115 115 and its -phenylenevinylene)s and oligo and -phenylenevinylene)s p Streptomyces griseoloalbus -mediated synthesis of 1,2-orthoesters of carbohydrates and the -mediated synthesis of 1,2-orthoesters 6 - conjugated polymers for enhanced solid-state luminescence: Synthesis and for enhanced solid-state luminescence: - conjugated polymers π glycosidation reactions of 4-pentenyl orthoesters Bulletin of the Chemical Society of Japan 80(3):553-560;Mar 2007 application in soymilk hydrolysis World Journal of Microbiology and Biotechnology 23(6):859-864:June 2007 Production of á-galactosidase by a novel actinomycete Fluorescent tagged probing agent and structure-directing amphiphilic molecular design Fluorescent tagged probing agent and structure-directing amphiphilic molecular process for polyaniline nanomaterials via self-assembly Journal of Physical Chemistry C 111(9):3591-3600;8 Mar 2007 nanomaterials: Control selective micellar templates for polyaniline Single-molecular-system-based of shape, size, solid state ordering, and expanded chain to coillike conformation Macromolecules 40(20):7311-7319;02 Oct 2007 Interplay of dual reactivity in the reaction of pentafulvenes with 1,2,4- triazoline-3,5-diones: Interplay of dual reactivity in the reaction Experimental and theoretical investigations New Journal of Chemistry 2007 31(2):237-246;Feb Ionic liquid [bmim] PF SURESH (E) and SURESH (C H) a step-sintering technique Acta Materialia 55(17):5792-5801;Oct 2007 Direct synthesis of varistor-grade doped nanocrystalline ZnO and its densification through Direct synthesis of varistor-grade Iodine assisted palladium catalyzed ring opening of bicyclic hydrazines with organoboronic acids: Iodine assisted palladium catalyzed ring cyclopentenes and alkylidene cyclopentenes Stereoselective synthesis of functionalized Organic & Biomolecular Chemistry 5(24):4010-4019;2007 Structure control of Structure control of and RADHAKRISHNAN (K V) Molecular wire encapsulated into ð organogels: Efficient supramolecular light-harvesting into ð organogels: Efficient Molecular wire encapsulated emission Antennae with color-tunable International Ed Angewandte Chemie Aug 2007 46(33):6260-6265;20 liquid crystalline and photophysical properties of new bulky poly( photophysical properties of new bulky liquid crystalline and pendants tricyclodecane bearing (phenylenevinylene)s Macromolecules Apr 2007 40(7):2380-2391;3 18ANISHA (G S) and PREMA (P) 17 (M) (P) and JAYAKANNAN ANILKUMAR 16 (M) (P) and JAYAKANNAN ANILKUMAR 15 (K), SAJISHA (V S), ANJU (K S), RADHAKRISHNAN (K V), KRISHNAN SYAM ANAS (S), 14 (R T) and RADHAKRISHNAN (K V) ANAS (S), SAJISHA (V S), RANI (R), KUMARAN 13 (S) (P), SHUKLA (S K) and ANANTHAKUMAR ANAS (S), MANGALARAJA (R V), MUKUNDAN 12 SAJISHA (V S), JOSHNI JOHN, RANI (R), SURESH (E) ANAS (S), JUBI JOHN, 11 (M) (S R) and JAYAKANNAN AMRUTHA 10 (C) and SUBI J GEORGE VIJAYAKUMAR (V K), (A), PRAVEEN AJAYAGHOSH Sl No Description NATIONAL INSTITUTE OF INTERDISCIPLINARY SCIENCE & TECHNOLOGY Thiruvananthapuram 116 116 28BAIJU (KV),SHUKLA(S), SANDHYA (KS),JOSEJAMESandWARRIER (KGK) BAIJU(KV),SHAJESH(P),WUNDERLICH (W),MUKUNDAN (P),KUMAR (SR) 27 BAIJU(KV),PERIYAT (P),KRISHNAPILLAIMUKUNDAN (P),WARRIER (KGK) 26 BABU(N),SURESH(DS)andMOHANDAS(PN) 25 BABITHA(S),SOCCOL(CR)andPANDEY (A) 24 BABITHA(S),SOCCOL(CR)andPANDEY (A) 23 ASHA POORNA(C)andPREMA(P) 22 ARAVIND (PR),SITHARA(L),MUKUNDAN (P),KRISHNAPILLAI(P)andWARRIER (KGK 21 ANTONY(MJ)andJAYAKANNAN (M) 20 ANJANA(PS),SEBASTIAN(M T), AXELSSON(A-K)andALFORD(NeilMcN) 19 Description No Sl 111(21):7612-7622;31 May 2007 Journal ofPhysicalChemistry C Titania nanocrystalline sol-gel-derived of activity Photocatalytic 276(1-2):41-46;17 Oct2007 Journal ofMolecularCatalysisA-Chemical titania mesoporous Effect oftantalumadditiononanatasephasestabilityand photoactivityofaqueoussol-gelderived and WARRIER (KGK) 61(8-9):1751-1755;Apr 2007 Letters Materials titania nanocrystalline sol-gel on Enhanced photoactivityandanatasethermalstabilityofsilica-aluminamixedoxideadditives and WUNDERLICH(W) 52(1):71-80;Mar 2007 Geology Environmental Impact oftsunamiontextureandmineralogyamajorplacerdepositinsouthwestcoastIndia 2007 47(2):118-126;Apr Microbiology Basic of Journal Effect ofstressongrowth,pigmentproductionandmorphologyMonascusspinsolidcultures 98(8):1554-1560;May 2007 TechnologyBioresource Solid-state fermentationfortheproductionof 98(3):485-490;Feb 2007 TechnologyBioresource by solid-statefermentationanditsapplicationinwastepaperrecycling Production ofcellulase-freeendoxylanasefromnovelalkalophilicthermotolerent 61(11-12):2398-2401;May 2007 Letters Materials Silica alcogelsforpossiblenuclearwasteconfinement-Asimulatedstudy 111(44):12772-12780;Nov 82007 B Chemistry Physcial of Journal luminescent polypyrrole nanospheres Amphiphilic azobenzenesulfonicacidanionicsurfactantforwater-soluble, ordered,and 27(12):3445-3452;2007 Journal oftheEuropeanCeramicSociety Microwave dielectricpropertiesCeO 2 -0.5 AO-0.5 TiO -0.5 AO-0.5 Monascus 2 (A=Ca,Mg,Zn,Mn,Co,Ni,W) ceramics (A=Ca,Mg,Zn,Mn,Co,Ni,W) pigmentsfronjackfruitseed Bacillus pumilus Bacillus ) ANNUAL REPORT 2007-2008 117 117 SURESH (C H) and fruit syzygium cumini formation in a La-containing AZ91 alloy 12 Al 17 antioxidant studies on in vitro ] undeca-9,11-diones and the formation of ] undeca-9,11-diones and the formation - doped fluorophosphate glasses for red emission - doped fluorophosphate [4,8] 3+ .0 [2,6] Journal of Materials Science 42(19):8374-8376;October 2007 Antimicrobial activity and chemical composition of essential oil from hedychium coronarium Antimicrobial activity and chemical composition of essential oil from hedychium Phytotherapy Research 21(5):439-443;May 2007 Chemical composition and Antibacterial activity of kauranes from annona squamosa L. pericarp Asian Journal of Chemistry 19(4):2773-2778;Jul-Aug 2007 and AJAY KUMAR (R) KUMAR and AJAY Synthesis of novel highly functionalized biologically active polycyclic caged amides Letters Tetrahedron 48(35):6204-6208;27 Aug 2007 SURESH DAS alkylation of a cage enone: Synthesis of aralkyl substituted Friedel-crafts tetracyclo[5.3.1.0 Journal of the Science of Food and Agriculture 87(14):2560-2569;Nov 2007 Design and synthesis of squaraine based near infrared fluorescent probes Design and synthesis of squaraine based Tetrahedron 2007 63(7):1617-1623;12 Feb Effect of Pb and Sb additions on the precipitation kinetics of AZ91 magnesium alloy Effect of Pb and Sb additions on the precipitation Materials Science & Engineering A 457(1-2):275-281;25 May 2007 Observation of the suppression of Mg Characterization of Eu Characterization of and WARRIER (K G K) (K and WARRIER titania synthesized through aqueous of neodymium doped mesoporous Enhanced photoactivity sol-gel method and Technology Journal of Sol-Gel Science 2007 43(3):283-290;Sep fascinating novel cage compounds with pyrrole and thiophene using montmorillonite K-10 fascinating novel cage compounds with Letters Tetrahedron 48(34):6059-6063;20 Aug 2007 Journal of Non-Crystalline Solids Journal of Non-Crystalline May 2007 353(13-15):1397-1401;15 38BENHERLAL (P S) and ARUMUGHAN (C) 37 RAJAN and EMILIA ABRAHAM (T) AKHILA BEENA JOY, 36 and SOBHANA (D) JOY BEENA 35 LAKSHMANAN MANGALAM S NAIR, DIVYA BEENA JAMES, VIJI (S), SOUMINI MATHEW, 34 BEENA JAMES, SURESH (E) and MANGALAM S NAIR 33 (U), ALEX (S), GEORGE THOMAS (K), BASHEER (M C), SANTHOSH 32 (B C) (A), PILLAI (U T S) and PAI BALASUBRAMANI (N), SURESH (M), SRINIVASAN 31 (B C) (A), PILLAI (U T S) and PAI (N), SRINIVASAN BALASUBRAMANI 30 K) and REDDY (M L P) (C (P), JAYASANKAR (R), BABU BALAKRISHNAIAH (R), VIJAYA 29 (P) KRISHNA PILLAI (P), MUKUNDAN (P), WUNDERLICH (W), PERIYAT BAIJU (K), Sl No Description NATIONAL INSTITUTE OF INTERDISCIPLINARY SCIENCE & TECHNOLOGY Thiruvananthapuram 118 118 48BIJU (A),VINOD(K),SARUN (PM)andSYAMAPRASAD (U) BIJU(A),VINOD(K), ALOYSIUS (RP)andSYAMAPRASAD (U) 47 BIJU(A),SYAMAPRASAD (U),RAO(A),XU(JG),SIVAKUMAR (KM)and KUO (YK) 46 BIJU(A),SARUN(PM),VINU(S),GURUSWAMY (P)andSYAMAPRASAD (U) 45 BIJU(A),SARUN(PM),ALOYSIUS (RP)andSYAMAPRASAD (U) 44 BIJU(A),SARUN(PM),ALOYSIUS (RP)andSYAMAPRASAD (U) 43 BIJU(A),GURUSWAMY (P)andSYAMAPRASAD (U) 42 BIJU(A),ALOYSIUS (RP)andSYAMAPRASAD (U) 41 BIJITHABALAN,DEEPTHI(LS)andGOPIDAS(KR) 40 BIJITHABALANandGOPIDAS(KR) 39 Description No Sl 90(7):072505 1-3;12Feb 2007 Letters Physics Applied Highly enhancedfluxpinninginPbandrareearthcodoped Bi-2212 431(1-2):49-55;4 Apr2007 Journal ofAlloysandCompounds Improved superconducting properties by La addition in (Bi,Pb)-2212 bulk superconductor 466(1-2):69-75;01 Nov2007 Superconductivity C: Physica Structural andtransportpropertiesofNddoped(Bi,Pb)-2212 Critical currentdensityandfluxpinninginaBi 433(1-2):68-72;16 May2007 Journal ofAlloysandCompounds additions Comparison ofsuperconductingpropertiesCeadded(Bi,Pb)-2212withotherrareearth 42(12):2057-2066;04 Dec2007 Bulletin Research Materials Structural andsuperconductingpropertiesofneodymiumaddedBi,Pb) 466(1-2):23-28;01 Nov2007 Superconductivity C: Physica Influence ofPbonstructuralandsuperconductingpropertiesrareearthmodifiedBi Structural andsuperconductingpropertiesofBi 9(14):2709-2712;5 Jul2007 Organic Letters β Interaction ofpyromelliticdiimidederivativeswith 13(18):5173-5185;15 Jun2007 Chemistry -AEuropeanJournal processes electron-transfer An anthracene-appended â-Cyclodextrin-based dyad: Study of self-assembly and photoinduced 20(8):781-784;Aug 2007 Superconductor ScienceandTechnology 61(3):648-654;Feb 2007 61(3):648-654;Feb Letters Materials -cyclodextrin: Rimbindingvsinclusioncomplexation 1.7 1.7 Pb Pb β 0.4 -cyclodextrin andanthracene-appended 0.4 Sr Sr 2-x 2-x La Yb x Ca x Ca 1.1 1.1 Cu Cu 2.1 2.1 O O 2 y Sr system y system 2 CaCu 2 O y 2 Sr 2 CaCu 2 O y ANNUAL REPORT 2007-2008 119 119 -pyrrolenevinylenes co perovskites 6 InTaO 2 as promising light-conversion molecular devices as promising light-conversion 3+ and Sr 6 InTaO 2 -acetyl-D-glucosamine chitin from colloidal N (A=Nb,Ta) dielectrics for microwave telecommunication applications dielectrics (A=Nb,Ta) 3 )O 1/4 Ti 2/4 A 1/4 Selective interactions of a few acridinium derivatives with single strand DNA: Study of photophysical and DNA binding interactions Journal of Physical Chemistry B 111(23):6549-6556;14 Jun 2007 Intramolecular Hydrogen bond energy in polyhydroxy systems: A critical comparison of molecular Intramolecular Hydrogen bond energy in polyhydroxy systems: A critical comparison approaches isodesmic and tailoring Journal of Physical Chemistry A 111(28):6472-6480;19 Jul 2007 Raman-spectroscopic investigation of Ba Journal of Solid State Chemistry 180(7):2143-2148;;July 2007 A new method for simultaneous estimation of unsaponifliable constituents of rice bran oil A new method for simultaneous estimation of unsaponifliable constituents using HPTLC Journal of Separation Science 30(16):2786-2793;Nov 2007 derived from divinylaryl bridged bispyrroles bridged divinylaryl from derived Macromolecules 40(8):2657-2665;17 Apr 2007 area on the properties of insulator-conductor Effect of interparticle distance and interfacial composites Applied Physics Letters 91(20):202904 1-3;12 Nov 2007 Synthesis, photophysical, and electroluminescent properties of Arylenevinylenes- Synthesis, photophysical, and electroluminescent Evaluation of fungal culture filtrate containing chitinase as a biocontrol agent against Evaluation of fungal culture filtrate containing armigera helicoverpa Journal of Applied Microbiology 103(5):1845-1852;Nov 2007 Doped Ca(Ca in solid state fermentation and their of endochitinase and chitobiase biosynthesis Fungal application for the production of 3-Phenyl-4-aroyl-5-isoxazolonate complexes of Tb 3-Phenyl-4-aroyl-5-isoxazolonate Bioresource Technology 98(14):2742-2748;Oct 2007 Inorganic Chemistry Communications 2007 10(4):393-396;Apr International Journal of Applied Ceramic Technology International Journal 4(1):60-74;Jan 2007 58ELIZABETH KURUVILLA and RAMAIAH (D) 58ELIZABETH KURUVILLA 57 (R L) DIAS (A), ABDUL KHALAM (L), SEBASTIAN (M T) and MOREIRA 56 DESHMUKH (M M), SURESH (C H) and GADRE (S R) 55 (D R), SUNDARESAN (A) and ARUMUGHAN (C) A), SOBAN KUMAR (L S DEEPAM 54 (M T) and JOSE JAMES (K S), SEBASTIAN DEEPA 53 (A) AJAYAGHOSH (Y N) and (A K), MOHAPATRA (A K), ASHISH (A), TRIPATHI BISWAS 52 (A) SHIRKE (S V), RAJPUT (J C) and PANDEY (R K), BINOD (P), SUKUMARAN 51 (A) (C), SUMA (P), SZAKACS (G) and PANDEY BINOD (P), SANDHYA 50V) and SEBASTIAN (M T) BIJUMON (P 49 L P) and FREIRE (R O) BIJU (S), REDDY (M Sl No Description NATIONAL INSTITUTE OF INTERDISCIPLINARY SCIENCE & TECHNOLOGY Thiruvananthapuram 120 120 68JAYAKANNAN (M)andDEEPA (P) JAMES(T),PADMANABHAN (M),WARRIER (KGK)andSUGUNAN (S) 67 GOKULNATH (S),PRABHURAJA(V),SANKAR (J)andCHANDRASHEKAR(TK) 66 GOKULNATH (S),PRABHURAJA(V)andCHANDRASHEKAR(TK) 65 GEORGE(S),JOSEJAMESand SEBASTIAN (MT) 64 GEORGE(SD),RAJESHKOMBAN, WARRIER (KGK),RADHAKRISHNAN (P), 63 GEORGE (M)andEMILIAABRAHAM(T) 62 GANGA(VB),SREEJA(T),SURESH(E)andLUXMI VARMA (R) 61 FRANCIS(R),JIJIL(CP),PRABHUA)andSURESHH) 60 FAN (L),SOCCOL(AT),PANDEY (A)andSOCCOL(CR) 59 Description No Sl 45(12):2351-2366;15 Jun2007 Chemistry Polymer A: Part Science Polymer of Journal and spheresbasedonpolyurethanes preparedvianovelmelttransurethanemethodology Solvent-induced self-organization approachforpolymericarchitecturesofmicropores, hexagons CuAl 2007(1):191-200;Jan 2007 European JournalofOrganicChemistry properties Smaragdyrin-Azobenzene conjugates:Syntheses,structure,andspectralelectrochemical 9(17):3355-3357;16 Aug2007 Organic Letters One-pot synthesisofoxidizedandreducedheptaphyrinswithunusualTFA binding 90(11):3522-3528;Nov 2007 Journal oftheAmericanCeramicSociety Giant permittivityofabismuthZincNiobate-Silvercomposite 28(1):123-132;Feb 2007 Thermophysics of Journal International Photoacoustic thermalcharacterizationofporousrare-earthphosphateceramics NAMPOORI (VPN)andVALLABHAN (CPG) 335(1-2):123-129;20 Apr2007 Pharmaceutics of Journal International pH sensitivealginate-guargumhydrogelforthecontrolleddeliveryofproteindrugs. 63(19):4134-4143;7 May2007 Tetrahedron hetero-dienophiles anddichlorocarbene:Synthesisofhighlyfunctionalizedmacrocycles Studies onthereactivityofcalix[4]arenederivedbis(spirodienone)withcarbo-and 48(22):6707-6718;19 Oct2007 Polymer comonomers –AtheoreticalstudyonreversalofLCST Synthesis ofpoly( 40(1):30-35;Jan 2007 LWT- FoodScienceandTechnology Agaricus brasiliensisbysubmergedfermentationanditsantitumoractivity Effect ofnutritionalandenvironmentalconditionsontheproductionexo-polysaccharide 103(2-3):248-254;15 June2007 Physics and Chemistry Materials boehmite xerogels 2 O 4 formationanditseffectoná-Al N -isopropylacrylamide) copolymer containing anhydride and imide 2 O 3 phaseevolutiononcalcinationofmetaliondoped ANNUAL REPORT 2007-2008 121 121 Lactobacillus (+)-lactic acid by sp. for the biosorption of CU(II) from L Sargassum and 5.5 ErZrO 2 Ulva fasciata under solid-state fermentation Biofiltration of toluene-contaminated air using an agro by-product-based filter bed Biofiltration of toluene-contaminated air using an agro by-product-based filter Applied Microbiology and Biotechnology 2007 74(1):215-220;Feb Evaluation of the marine algae aqueous solutions Bioresource Technology 98(2):452-455;Jan 2007 Development of squaraine dyes for photodynamic therapeutical applications: Synthesis and study of Development of squaraine dyes for photodynamic therapeutical applications: electronic factors in the dye formation reaction Arkivok (viii):296-310;2007 casei Letters in Applied Microbiology 44(6):582-587;Jun 2007 squaraine dye in solution and thin films: Concentration-, Chiral supramolecular assemblies of a and Solvent-induced chirality inversion Temperature-, Chemistry - A European Journal 13(20):5944-5951;06 Jul 2007 Synthesis, crystal structure, dielectric properties and potential use of nanocrystalline Synthesis, crystal structure, dielectric properties complex perovskite ceramic oxide Ba Materials Research Bulletin 42(12):1976-1985;04 Dec 2007 reagents: A simple, ring opening of azabicyclic olefins with organoindium Palladium-catalyzed cyclopentenes. clean and efficient synthesis of functionalized Letters Tetrahedron 48(40):7225-7227;01 Oct 2007 Polyurethane foam as an inert carrier for the production of Polyurethane and MOHANDAS (E) Ruthenium (II) trisbipyridine functionalized gold nanorods. Morphological changes and excited-state functionalized gold nanorods. Ruthenium (II) trisbipyridine interactions Journal of Physical Chemistry B Jun 2007 111(24):6839-6844;21 Low temperature synthesis of aluminium titanate by an aqueous sol-gel route of aluminium titanate by an aqueous Low temperature synthesis Materials Letters 61(3):790-793;Feb 2007 77 (B), HIMA (A M) and AJIT HARIDAS KRISHNAKUMAR 76 (R) and IYER (C S P) (S), BALASUBRAMANIAN KARTHIKEYAN 75 (K), REKHA (R A) and RAMAIAH (D) JYOTHISH 74 (K), MAHESH HARIHARAN and RAMAIAH (D) JYOTHISH 73 (S) and RADHAKRISHNAN (K V) JUBI JOHN, ANAS (S), SAJISHA (V S), VIJI 72 (R) (J), DIVAKAR KOSHY JOSE (R), JOHN (A M), THOMAS (J K), JOSE JAMES, 71 (A) (K M) and PANDEY JOHN (R P), NAMPOOTHIRI 70 (P V) KAMAT (P), GEORGE THOMAS (K) and JEBB (M), SUDEEP (P K), PRAMOD 69 (K G K) WARRIER (P), and (S), MUKUNDAN (M), ANANTHAKUMAR JAYASANKAR Sl No Description NATIONAL INSTITUTE OF INTERDISCIPLINARY SCIENCE & TECHNOLOGY Thiruvananthapuram 122 122 6MANI(J),ANANTHAKUMAR (S),MUKUNDAN (P)andWARRIER (KGK) 86 MAHESHHARIHARAN,SUNEESH(CK)andRAMAIAH(D) 85 MAHESHHARIHARAN,PRAKASH(PN)andRAMAIAH(D) 84 MAHADEVAN (K),RAGHUKANDANPAI (BC)andPILLAI(UTS) 83 LUXMI VARMA (R),GANGA(VB)andSURESH(E) 82 LI(S),KIM(Wook-Dong), KANEKO (S),PREMA(P),NAKAJIMA(M) 81 KUMUD KUMARI andEMILIAABRAHAM(T) 80 KUMAR (R),MISRACHANDRASHEKAR(TK)andSURESH(E) 79 78KUMAR (R),MISRACHANDRASHEKAR(TK),NAG(A),GOSWAMI (D),SURESH(E) Description No Sl 71(2):520-526;Feb 2007 Biochemistry and Biotechnology Bioscience, Escherichia coli 14(4):277-281;Aug 2007 Indian JournalofEngineering&MaterialsSciences 90(10):3091-3094;Oct 2007 90(10):3091-3094;Oct Journal oftheAmericanCeramicSociety alumina precursor Low-temperature fine-grainedalumia-aluminumtitanate compositesproducedfromatitania-coated 9(3):417-420;1 Feb2007 Organic Letters interactionsinanaqueousmedium Selective recognitionoftryptophanthroughinhibition intramolecular charge-transfer Encapsulation ofelectrondonor-acceptor dyadsin parameters ofAA6061-SiC Experimental investigationontheinfluenceofreinforcementandprecipitationhardening 72(3):1017-1019;2 Feb 2007 Journal ofOrganicChemistry Formation ofanewmacrocycle Photochemical rearrangementofCalix[4]arene-derivedBis(spirodienones): Expression ofrice( and KOBAYASHI (H) 98(9):1704-1710;July 2007 TechnologyBioresource Biosorption ofanionictextiledyesbynonviablebiomassfungiandyeast (1):43-45;Jan 2007 Communications Chemical quaterthiophene subunit Near IRabsorbingplanararomatic[34]octaphyrins(1.1.0.1.1.0.0.0)containinga (27):4552-4562;Sep 2007 European JournalofOrganicChemistry nonlinear opticalproperties One-pot synthesisofcore-modifiedRubyrin,Octaphyrin,andDodecaphyrin:Characterization and SURESH(CH) 111(41):11940-11947;18 Oct2007 B Chemistry Physical of Journal and enhancementinrateofelectron-transferreaction andcharacterization Oryza sativa p composites L.var.Nipponbare) α -galactosidase genes in β -cyclodextrin cavity:Unusualplanarization ANNUAL REPORT 2007-2008 123 123 ceramics 3 )O 2/3 microwave ceramics Nb 3 1/3 TiO x Ce 1–3x/2 ceramics microwave ceramics 3 3 )O )O 2/3 1/2 Ta Ta 1/3 1/2 aromatic core-modified hexaphyrins: Syntheses, characterization and structural π Journal of the European Ceramic Society 27(8-9):2803-2809;2007 Chemistry of Materials 19(26):6548-6554;25 Dec 2007 and DIAS (A) Optical phonon modes and dielectric behavior of Sr and SEBASTIAN (M T) FDTD analysis of rectangular dielectric resonator antenna Journal of the European Ceramic Society 27(8-9):2753-2757;2007 of Raman spectroscopic investigations on the crystal structure and phonon modes Ba(RE 26 diversities Journal of Organic Chemistry 2007 72(4):1153-1160;16 Feb NAIDU (G R K) monitoring toxic uranium in environmental samples Ion imprinted polymer based sensor for Analytica Chimica Acta 582(1):147-153;16 Jan 2007 Investigation of the role of chelating ligand in the synthesis of ion-imprinted polymeric resins on Investigation of the role of chelating ligand the selective enrichment of uranium (VI) Analytica Chimica Acta 587(2):263-271;28 Mar 2007 and ARUMUGHAN (C) of micronutrient rich red palm olein Process technology for the production Journal of the American Oil Chemists Society 84(6):587-596;Jun 2007 Effect of dopants on microwave dielectric properties of Ba(Zn Effect of dopants on profile of phosphine ligands Quantitative assessment of the stereoelectronic Inorganic Chemistry 46(25):10800-10809;10 Dec 2007 Effect of dopants on the low temperature microwave dielectric properties of the low temperature microwave dielectric Effect of dopants on Ba(Zn Science: Materials in Electronics Journal of Materials 18(4):441-446;Apr 2007 Journal of the European Ceramic Society Journal of the European 27(8-9):2827-2833;2007 96 (F M) (M T), MATINAGA (R P S M), SUBODH (G), SEBASTIAN MOREIRA (R L), LOBO 95 DIAS (A) MOREIRA (R L), ABDUL KHALAM (L), SEBASTIAN (M T) and 94 SUMA (M N), BIJUMON (P V) MOHANAN (P), MRIDULA (S), BINUPAUL, 93 (R), CHANDRASHEKAR (T K) and JOSHI (B S) MISRA (R), KUMAR 92 (K), KALA (R), MARY GLADIS (J), PRASADA RAO (T) and METILDA (P), PRASAD 91 (G) and PRASADA RAO (T) METILDA (P), MARY GLADIS (J), VENKATESWARAN 90 (A) (P N), BALACHANDRAN (C), SAMUEL (T), SUNDARESAN MAYAMOL 89 (J), THOMAS (T) and SURESH (C H) MATHEW 88 (M T) and SEBASTIAN RAAMA VARMA MANOJ 87 (N D) and KATARIA MANOJ RAAMA VARMA Sl No Description NATIONAL INSTITUTE OF INTERDISCIPLINARY SCIENCE & TECHNOLOGY Thiruvananthapuram 124 124 0 PANNEERSELVAM (R),SAVITHRI (S)andSURENDER(GD) 105 PADMA KUMAR (H),JOSEPH(JT),THOMASK),MANOJ RAAMAVARMA, 104 NISHARANI,BEENAJOY andEMILIAABRAHAM 103 NIRMALAMENON(A),PADMAKUMARI (B), (K P),SANKARIKUTTY 102 NIMINARAYANAN, PRIYA (M),AJITHARIDASandMANILAL(VB) 101 NILADEVI(KN),SUKUMARAN (RK)andPREMA(P) 100 NESON VARGHESE, VINOD(K),ABHILASHKUMAR (RG),SYAMAPRASAD (U) 99 98NARAYAN (G),SALEESHKUMAR (NS),PAUL (S),SRINIVAS (O), NAIR(KR),PRABHAKARRAO(P),RAJ(AV),JOSEPH(SK),CHANDRAN(MR)and 97 Description No Sl 132(1-3):159-171;1 Aug2007 Chemical EngineeringJournal fluidised bed CFD basedinvestigationsonhydrodynamicsandenergydissipation duetosolidmotioninliquid 143(1-3):51-54;25 oct2007 Materials ScienceandEngineeringB resonators Influence ofzincoxideadditiononLnTiTaO ANNAMMA JOHNandSAMSOLOMON 45(1):48-53:1 Jan2007 Biology Pharmaceutical L-Tyrosine intoL-DOPA, anAnti-Parkinson’s drug Cell suspensionculturesof 19(2):105-109;Mar/Apr 2007 Journal ofEssentialOilResearch Effects ofprocessingontheflavorcompoundsIndianFresh Ginger(ZingiberOfficinaleRosc.) SREEKUMAR (MM)andARUMUGHAM(C) SUMATHIKUTTY (MA), 13(1):14-20;Feb 2007 Anaerobe Isolation andculturingofamostcommonanaerobicciliate,Metopussp. 2007 34(10):665-674;Oct Journal ofIndustrialMicrobiologyandBiotechnology fermentation Utilization ofricestrawforlaccaseproductionby 102(4):043914-1-4;15 Aug2007 Physics Applied of Journal Influence ofreactivitysheathmaterialswithMg/BonsuperconductingpropertiesMgB and SUNDARESAN(A) 189(2-3):405-413;25 Jun2007 Chemistry A: Photobiology and Photochemistry of Journal bolaamphiphiles Aggregation andphotoresponsivebehaviorofazobenzene-oligomethylene-glucopyranoside JAYARAMAN (N)andSURESHDAS 90(11):3656-3659;Nov 2007 Journal oftheAmericanCeramicSociety New familyofdielectricmaterialsinca-y-ti-nb-o systemhavingpyrochloretypestructure PETER KOSHY portulaca grandiflora 6 (Ln=Pr, SmandDY) materialsfordielectric as potentcatalystsforbiotransformationof streptomyces psammoticus streptomyces in solid-state in 2 ANNUAL REPORT 2007-2008 125 125 x Bi 3-x Sm 3 -Ethyl Thiomethyl phophorodithioate) S -Diethyl O,O - novel environmental secure pigments - novel environmental x ) 3 O 2 (RE 1-x ) 2 (x=0, 1, 2 or 3) -selective fluorescent sensor based on a 1,3-alternate thiacalix[4] arene anchored with -selective fluorescent sensor based on a 1,3-alternate thiacalix[4] arene anchored 25 Hg2+ O (CeO 2 1 ) 2 Nb 7 Dyes and Pigments 73(3):292-297;2007 in natural waters Electroanalysis 19(11):1195-1200;June 2007 A new Molecularly imprinted polymer-based potentiometric sensor for degradation product potentiometric sensor for degradation Molecularly imprinted polymer-based acid 1. Methylphosphonic of chemical warfare agents Part Talanta 71(5):1976-1980;30 Mar 2007 (R) VARMA LUXMI Biomimetic sensors for toxic pesticides and inorganics based on optoelectronic/ electrochemical transducers - an overview Critical Reviews in Analytical Chemistry 37(3):191-210;2007 Design and development of imprinted polymer inclusion membrane-based field monitoring device Design and development of imprinted for trace determination of of Phorate ( PRASADA RAO (T) based potentiometric sensor for atrazine Molecularly imprinted polymer (biomimetic) Sensors and Actuators B: Chemical 123(1):65-70;10 April 2007 Microwave dielectric properties of novel lithium containing pyrochlore type oxides: Li Microwave dielectric properties of novel Ti nanorods through electrostatic interactions Preferential end functionalization of au Journal of the American Chemical Society 129(21):6712-6713;30 May 2007 (TiO Aqueous colloidal sol-gel route to synthesize nanosized ceria-doped titania having high surface route to synthesize nanosized ceria-doped Aqueous colloidal sol-gel anatase phase stability area and increased and Technology Journal of Sol-Gel Science 2007 43(3):299-304;Sep four 8-quinolinoloxy groups 8-quinolinoloxy four Inorganic Chemistry 46(16):6277-6282;6 Aug 2007 Materials Letters 61(19-20):4188-4191;Aug 2007 114 SREEJA (T), REDDY (M L P) and (L), GANGA (V B), THIRUMALAI (R), PRAVEEN 113 (M V S) (K), PRASADA RAO (T) and SURYANARAYANA (K P), PRASAD PRATHISH 112 KALA (R) and MARY GLADIS (J) PRASADA RAO (T), PRASAD (K), 111 GLADIS (J), NAIDU (G R) and PRASADA RAO (T) (K P), MARY PRASAD (K), PRATHISH 110 (K P), MARY GLADIS (J), NAIDU (G R K), and PRASAD (K), PRATHISH 109 (S T S) and GEORGE THOMAS (K) PRAMOD (P), JOSEPH 108PRABHAKAR RAO (P), RAVINDRAN NAIR (K), PETER KOSHY and VAIDYAN (V K) and VAIDYAN NAIR (K), PETER KOSHY RAVINDRAN 108PRABHAKAR RAO (P), 107 RAO (P) and REDDY (M L P) PRABHAKAR 106 G K) (K and WARRIER (P), KRISHNA PILLAI (P) MUKUNDAN (P), BAIJU (K V), PERIYAT Sl No Description NATIONAL INSTITUTE OF INTERDISCIPLINARY SCIENCE & TECHNOLOGY Thiruvananthapuram 126 126 2 RAMACHANDRAN(S),FONTANILLE (P),PANDEY (A)andLARROCHE(C) 124 RAJESHKOMBN, SHAJESH(P),SEIDEL(O),MUKUNDAN (P)andWARRIER (KGK) 123 RAJAN(TPD),PRABHU(KN),PILLAI(RM) andPAI (B C) 122 RAJAN(TPD),PILLAI(RM),PAI (BC),SATYANARAYANA (KG)andROHATGI (PK) 121 RAJAMMA(R)andSEBASTIAN(MT) 120 RAGHAVAN (P), SATHY CHANDRASEKHAR, VOGT (V),GOCK(E)andSURESH(N) 119 118RADHAKRISHNAN (KV),ANAS(S),SURESH(E),KOGA (N)andSURESH(CH) PRIYA CAROL,SREEJITH(S)andAJAYAGHOSH (A) 117 PRIYA (M),AJITHARIDASandMANILAL(VB) 116 PRAVEEN (RS),NAIDU(GRK),andPRASADARAO(T) 115 Description No Sl 80(3):484-490;Mar 2007 Bulletin oftheChemicalSocietyJapan completely controlthecrystalpackingandhost-guestcomplexation 44(2):155-160;Feb 2007 Microbiology Applied in Letters fermentation andtheiruseascatalystingluconicacidproduction Spores ofAspergillusnigerasreservoirglucoseoxidase synthesizedduringsolid-state 17(10):1682-1690;9 Jul2007 Advanced Functional Materials lanthanum phosphatepowdersandnanocoatings A facilesol-gelstrategyforthesynthesisofrod-shaped, nanocrystalline, high-surface-area 67(1):70-78;Jan 2007 Composites ScienceandTechnology composites Solidification andcasting/mouldinterfacialheattransfercharacteristicsofaluminummatrix 67(15-16):3369-3377;Dec 2007 Composites Science&Technology processed bydifferentstircastingroutes Fabrication andcharacterizationofAl-7Si-0.35Mg/flyashmetalmatrixcomposites Microwave dielectricpropertiesofLa 38(1-2):33-42;Dec 2007 Science Clay Applied pretreatment andfrothflotation-Part 1 Additional investigationsontheseparationoftitanoferrousimpuritiesfromkaolinbyhighshear Molecular recognitioninanorganichost-guestcomplex:CH...OandCH... 2(3):338-348;2007 Chemistry -AnAsianJournal Ratiometric andnear-infrared molecularprobesforthedetectionandimagingofzincions 41(20):4639-4645;Dec 2007 Water Research Involvement ofprotozoainanaerobicwastewatertreatmentprocess 600(1-2):205-213;26 Sep2007 Analytica ChimicaActa line flowinjection-flameatomicabsorptionspectrometrydeterminationoflead Dithiocarbamate fuctionalizedorsurfacesorbedmerrifieldresinbeadsascolumnmaterialsforon 90(8):2472-2475;Aug 2007 Journal oftheAmericanCeramicSociety 6 Mg 4 A 2 W 2 O 24 [A=Ta andNb]ceramics π interactions ANNUAL REPORT 2007-2008 127 127 p in a micellar medium 2+ composites - A theoretical p -metallocene-based cyclic[2]pyrroles -metallocene-based Phytochemical characterization of defatted rice bran and optimization of a process for their Phytochemical characterization of defatted rice bran and optimization of a process extraction and enrichment. Bioresource Technology 98(16):3037-3043;Nov 2007 Rapid reduction and complexation of vanadium by 1-phenyl-3-methyl-4-toluoyl-5-pyrazolone: Spectroscopic characterization and structure modelling Polyhedron 26(17):5016-5022; 30 Oct 2007 Dual-mode semisquaraine-based sensor for selective detection of Hg Enhanced extraction and separation of Zirconium (IV) and hafnium (IV) with Enhanced extraction and separation of of various neutral organophosphorus 3-phenyl-4-benzoyl-5-isoxazolone in presence extractants Radiochimica Acta 95(5):289-295;May 2007 Organic Letters 9(1):121-124;4 Jan 2007 composites (Communication) A Metallurgical and Materials Transactions 38(7):1666-1670;Jul 2007 (B C) (R) and PAI ARUL KUMAR a water model for metal matrix composites synthesis Optimization of mixing parameters through Materials and Design 28(3):871-881;2007 Influence of interfacial reaction on the fluidity of A356 Al-SiC Influence of interfacial reaction on the interfacial reaction products in Al-SiC A novel approach for extracting and characterizing Separation of matrix alloy and reinforcement from aluminum metal matrix composites scrap by salt metal matrix composites scrap by alloy and reinforcement from aluminum Separation of matrix addition flux Bulletin of Materials Science 2007 30(4):393-398;Aug ansa Organic Letters Nov 2007 9(23):4769-4772;8 approach A Metallurgical and Materials Transactions 38(10):2531-2539;Oct 2007 133 RENUKA DEVI (R) and ARUMUGHAN (C) 132 L P) (P N), SURESH (C H) and REDDY (M REMYA 131 (K) and RAMAIAH (D) REKHA (R A), JYOTHISH 130(K J), REDDY (A V), SHAIBU (B S) and REDDY (M L P) REDDY 129 (K R), (C), AMARANATHAN (V M), PILLAI (R M), MAHATO SREEKUMAR (K R), RAVI 128RAVI (K R), PILLAI (R M), PAI (B C) and CHAKRABORTY (M) (B C) and CHAKRABORTY PILLAI (R M), PAI (K R), 128RAVI 127 (B C) and CHAKRABORTY (M) (K R), PILLAI (R M), PAI RAVI 126 (M) (B C) and CHAKRABORTY (K R), PILLAI (R M), PAI RAVI 125 (A) (S) and SRINIVASAN RAMAKRISHNAN Sl No Description NATIONAL INSTITUTE OF INTERDISCIPLINARY SCIENCE & TECHNOLOGY Thiruvananthapuram 128 128 4 SAJIMON(MC),RAMAIAH(D),SURESH(CH),ADAM(W),LEWIS(F D)and 143 SAJIALEX,BASHEER(MC),ARUN(KT),RAMAIAH(D)andSURESHDAS 142 ROSYANTONYandPILLAI(CKS) 141 ROJANPJOHN,RAJEEVKSUKUMARAN, NAMPOOTHIRI(KM)andPANDEY (A) 140 ROJANPJOHN,NAMPOOTHIRI(KM)andPANDEY (A) 139 138 ROJANPJOHN,NAMPOOTHIRI(KM)andPANDEY (A) 137 RIYAS (S),KRISHNAN(G),andMOHANDAS(PN) RESHMI(JR),BIJU(S)andREDDY(MLP) 136 RENUKADEVI(R),JAYALEKSHMY (A)andARUMUGHAN(C) 135 RENUKADEVI(R)andARUMUGHAN(C) 134 Description No Sl 10(9):1091-1094;Sep 2007 10(9):1091-1094;Sep Communications Chemistry Inorganic 129(30):9439-9445;01 Aug 2007 Journal oftheAmericanChemical Society Photochromic Dibenzobarrlenes:Long-livedtripletbiradical intermediates GEORGE (MV) 111(17):3226-3230;3 May2007 Journal ofPhysicalChemistryA Evidence fortheformationofJ-typedimeraggregatesin aprotic solvents Aggregation propertiesofheavyatomsubstitutedsquaraine dyes: 14(5):529-531;Sep 2007 Indian JournalofChemicalTechnology Synthesis, characterizationandthermalstudiesofboroncontainingphenoliccardanolicpolymers 36(3):262-267;01 Oct2007 Journal Engineering Biochemical from cassavabagasseusingmixedcultureoflactobacillibyresponsesurfacemethodology Statistical optimizationofsimultaneoussaccharificationandL(+)-lacticacidfermentation 47(1):25-30;Feb 2007 Journal ofBasicMicrobiology delbrueckii Production ofL(+)lacticacidfromcassavastarchhydrolyzatebyimmobilized 74(3):524-534;Mar 2007 Biotechnology and Microbiology Applied future perspectives(MiniReview) Fermentative productionoflacticacidfrombiomass:Anoverviewonprocessdevelopmentsand 2007 106(5):255-264;Oct Ceramics Applied in Advances Anatase-rutile transformationindopedtitaniaunderargonandhydrogenatmospheres 3,4,5-Trisbenzyloxy benzoicacidasanewphoto-sensitizerforTb 104(2):658-664;2007 Chemistry Food Antioxidant efficacyofphytochemicalextractsfromdefattedricebraninthebulkoilsystem 2007 45(10):2014-2021;Oct Food andChemicalToxicology Antiradical efficacyofphytochemicalextractsfromdefattedricebran 3 +ion Lactobacillus ANNUAL REPORT 2007-2008 129 129 vinyl radical cyclization -Butyrolactones from exo-trig γ - type perovskites 18 O 5 B 6 SnH-Mediated 5- 3 -Bu n -tetraoctyl-3-oxapentane-1,5-diamide impregnated magnetic particles for the uptake of -tetraoctyl-3-oxapentane-1,5-diamide Baylis-Hillman adducts of Isatin Australian Journal of Chemistry 60(4):296-301;Apr 2007 A facile and efficient stereoselective synthesis of highly functionalised trisubstituted alkene A facile and efficient stereoselective synthesis of highly functionalised trisubstituted ferrocenealdehyde of derivatives Letters Tetrahedron 48(52):9190-9194;24 Dec 2007 Synthetic Communications 37(14):2291-2299;2007 A facile and efficient synthesis of functionalized Silica chloride-catalyzed one-pot isomerization-chlorination, arylation, and Silica chloride-catalyzed one-pot isomerization-chlorination, etherification of Baylis-Hillman adducts Australian Journal of Chemistry 60:850-856;2007 adducts Synthesis of 3-Heteroaryl-substituted tetrahydrofurans from the Baylis-Hillman of heteroarylaldehydes by N,N,N’,N’ waste streams lanthanides and actinides from nuclear Radiochimica Acta 95(3):159-164;Mar 2007 Editorial to “Journal of the European Ceramic Society” Special Issue 2007 of the European Ceramic Society” Editorial to “Journal Journal of the European Ceramic Society 27(8-9):2745;2007 Enhanced flux pinning of an Nd-added (Bi,Pb)-2212 superconductor (Bi,Pb)-2212 Nd-added an of pinning flux Enhanced Journal of the American Ceramic Society 90(10):3138-3141;Oct 2007 east India Investigation on a gray kaolin from south Applied Clay Science 37(1-2):32-46;Jun 2007 Development of ultrafine grain aluminium-graphite metal matrix composite by equal grain aluminium-graphite metal Development of ultrafine channel angular pressing and Technology Composites Science 2007 67(6):1275-1279;May Microwave dielectric properties of A Microwave dielectric Journal of the American Ceramic Society Journal of the American 2007 90(2):496-501;Feb 153 and SUCHITHRA (M) VISWAMBHARAN (V), BABY SHANMUGAM (P), VAITHIYANATHAN 152 (B) (V) and VISWAMBHARAN SHANMUGAM (P), VAITHIYANATHAN 151 (V) (B) and VAITHIYANATHAN SHANMUGAM (P), RAJASINGH (P), VISWAMBHARAN 150 (V) and VAITHIYANATHAN VISWAMBHARAN (P), BABY SHANMUGAM 149 (M S) and MANCHANDA (V K) SHAIBU (B S), REDDY (M L P), MURALI 148SEBASTIAN (M T), UUSIMAKI (Antti) and JANTUNEN (Heli) 148SEBASTIAN (M T), 147 (S) CHANDRASEKHAR and RAMASWAMY SATHY 146 (U) (P) and SYAMAPRASAD SARUN (P M), BIJU (A), GURUSWAMY 145 (M) (B C) and BRAHMAKUMAR (K R), PAI (R M), RAVI (M), PILLAI SARAVANAN 144 (N I) and SEBASTIAN (M T) SANTHA Sl No Description NATIONAL INSTITUTE OF INTERDISCIPLINARY SCIENCE & TECHNOLOGY Thiruvananthapuram 130 130 6 SMITHA (P)andASHA(SK) 163 SINGHANIA(RR),SUKUMARAN (RK)andPANDEY (A) 162 SINGH(SK),PATEL (AK),AHMED (SU),NAMPOOTHIRI(KM),andPANDEY (A) 161 SINDHUMATHEW, EMILIAABRAHAM(T)andSUDHEESH(S) 160 SINDHUMATHEW andEMILIAABRAHAM(T) 159 158SIMI (CK)andEMILIAABRAHAM(T) SIMI(CK)andEMILIAABRAHAM(T) 157 SHYNI(R),BIJU(S),REDDY(MLP),COWLEY(AH)andFINDLATER (M) 156 SHARMA(A),KATIYAR (M),DEEPAK, SHUKLA(SK)andSEKI(S) 155 SHANMUGAM(P),BABY VISWAMBHARAN andSUCHITHRA(M) 154 Description No Sl 111(23):6364-6373;14 Jun2007 B Chemistry Physical of Journal Structure controlforfinetuningfluorescenceemissionfrom side-chainAzobenzenepolymers 142(1):60-70;Jul 2007 Biotechnology‘ and Biochemistry Applied optimization Improved cellulaseproductionby 66(8):660-666;Aug 2007 Journal ofScientific&IndustrialResearch Identification andphylogeneticanalysisofTEMgenefromsoilisolates 44(2):48-52;1 Feb 2007 Journal ofMolecularCatalysisB-Enzymatic hansenii Rapid conversionofferulicacidto4-vinylguaiacolandvanillinmetabolitesbyDebaryomyces 105(2):579-589;2007 Chemistry Food Physico-chemical characterizationofstarchferulatesdifferentdegreessubstitution 30(3):173-180:May 2007 Engineering Biosystems and Bioprocess Hydrophobic graftedandcross-linkedstarchnanoparticlesfordrugdelivery 32(1):17-23;Sep 2007 Sciences Pharmaceutical of Journal European release applications Encapsulation ofcrosslinkedsubtilisinmicrocrystalsinhydrogelbeadsforcontrolled 46(26):11025-11030;24 Dec2007 Chemistry Inorganic xanthene-9-carboxylates Synthesis, crystalstructures,andphotophysicalpropertiesofhomodinuclearlanthanide 102(10)Art.No.104902;15 Nov2007 Physics Applied of Journal photodegradation in polysilanes Effect ofambient,excitationintensityandwavelength,chemicalstructureon 9(21):4095-4098;11 Oct2007 Organic Letters Baylis-Hillman adductsofisatinandheteroaldehydeswithazomethineylidesvia[3+2]-cycloaddition Synthesis ofnovelfunctionalized3-spiropyrrolizidineand3-spiropyrrolidineoxindolesfrom Trichoderma reesei RUT C30 under SSF throughprocess RUTC30underSSF ANNUAL REPORT 2007-2008 131 131 metal matrix composite from silica gel In situ 4 0 2 Effect of Pb addition on ageing behavior of AZ91 magnesium alloy Materials Science and Engineering A 452-453:87-92;15 Apr 2007 A study on the thermodynamics of in situ MgAl204/ Al MMC formation using amorphous A study on the thermodynamics of in situ MgAl204/ Al MMC formation using silica sources Journal of Materials Processing Technology 192:588-594;Sp.Iss SI 1 Oct 2007 alloy Influence of Si and Sb additions on the corrosion behavior of AZ91 magnesium Intermetallics 15:1511-1517;2007 Synthesis of an Al/MgAl Effects of individual and combined additions of Be,Mn,Ca and Sr on the solidificaion behaviour, Effects of individual and combined additions alloy Al-7Si-0.3Mg-0.8Fe structure and mechanical properties of Materials Science and Engineering A 460-461:561-573;15 Jul 2007 LEE (Hea-Yeon) and KAWAI (T) and KAWAI LEE (Hea-Yeon) carbon nanotubes and their characterization A review of DNA functionalized /grafted Sensors and Actuators B 122(2):672-682;26 Mar 2007 Synthesis of biocompatible hydrophobic silica-gelatin nano-hybrid by sol-gel process Synthesis of biocompatible hydrophobic Colloids and Surfaces B: Biointerfaces 55(1):38-43;15 Mar 2007 characteristics of subcritically dried silica Effect of aging temperature on the porosity aerogels Journal of Porous Materials 14(1)2007:1-6;Mar 2007 Antiwetting silica-gelatin nanohybrid and transparent nano coatings synthesised nanohybrid and transparent nano Antiwetting silica-gelatin sol-gel process through an aqueous and Technology Journal of Sol-Gel Science 2007 42(2):157-163;May Silica-gelatin bio-hybrid and transparent nano-coatings through sol-gel technique and transparent nano-coatings through Silica-gelatin bio-hybrid Materials Chemistry and Physics June 2007 103(2-3):318-322;15 Journal of the American Ceramic Society 2007 90(9):2905-2911;Sep 173 (B C) (A), PILLAI (U T S) and PAI SRINIVASAN 172 (B C) MUDALI (U), PILLAI (U T S) and PAI (A), NINGSHEN (S), KAMACHI SRINIVASAN 171 (M) (B C) and CHAKRABORTY (V M), PILLAI (R M), PAI SREEKUMAR 170 CHAKRABORTY (M) (B C) and (V M), PILLAI (R M), PAI SREEKUMAR 169 (B C) (S S), PILLAI (R M), RAJAN (T P D) and PAI KUMARI SREEJA 168SOBHI DANIEL, PRASADA RAO (T), RAO (K S), USHA RANI (S), NAIDU (G R K), RAO (T), RAO (K S), USHA RANI 168SOBHI DANIEL, PRASADA 167 (K G K) (P) and WARRIER (S), KRISHNA PILLAI SMITHA (S), SHAJESH (P), RAJESH KUMAR 166 (K G K) (P), NAIR (T D R) and WARRIER (P), MUKUNDAN SMITHA (S), SHAJESH 165 (K G K) (P) and WARRIER (S), SHAJESH (P), MUKUNDAN SMITHA 164 (K G K) PILLAI (P) and WARRIER (P), KRISHNA (S), MUKUNDAN SMITHA Sl No Description NATIONAL INSTITUTE OF INTERDISCIPLINARY SCIENCE & TECHNOLOGY Thiruvananthapuram 132 132 8 SUNDARESAN(N) andSURESH(CH) 183 SUMITRA(R),SINGH(SK),LARROCHE(C),SOCCOL(CR) andPANDEY (A) 182 SUMA(MN),BIJUMON(PV),SEBASTIANT)andMOHANAN(P) 181 SUDHA(JD),REENA(VL)andPAVITHRAN (C) 180 SUDHA(JD)andSASIKALA(TS) 179 178SUBODH (G),PAVITHRAN (C),MOHANAN(P)andSEBASTIAN(MT) SUBODH(G),JOSEPH(M),MOHANAN(P)andSEBASTIAN(MT) 177 SUBODH(G),JOSEJAMES,SEBASTIAN(MT),PANIAGO (R),DIAS(A)andMOREIRA(RL) 176 SUBODH(G)andSEBASTIAN(MT) 175 SUBODH(G)andSEBASTIAN(MT) 174 Description No Sl 19(16):4077-4082;07 Aug2007 Materials of Chemistry 90(11):3507-3511;Nov 2007 Journal oftheAmericanCeramicSociety 136(1):50-56;15 Jan2007 Materials ScienceandEngineeringB 90(7):2266-2268;Jul 2007 Journal oftheAmericanCeramicSociety 3(3):1172-1182;May-Jun 2007 Journal ofChemicalTheoryandComputation alkali metalionsforphosphateanioninDNA A base-sugar-phosphate three-layer ONIOMmodelforcationbinding:Relativebindingaffinitiesof 98(10):2000-2009;July 2007 TechnologyBioresource Oil cakesandtheirbiotechnologicalapplications-Areview 27(8-9):3001-3004;2007 Journal oftheEuropeanCeramicSociety A compacthybridCPWfedplanarmonopole/dielectricresonatorantenna 45(19):2664-2673;01 Oct2007 Physics Polymer B: Part Science: Polymer of Journal template polymerizationusingamphiphilicdopant,3-pentadecylphenol4-sulphonicacid Facile greenstrategyformicro/nanostructuredconductingpolyaniline-claynanocompositevia 48(1):338-347;5 Jan2007 Polymer intercalating agentcumdopant nanocomposite (PANICN) using3-pentadecylphenylphosphoricacid(PDPPA) asanovel Studies ontheformationofself-assembled nano/microstructuredpolyaniline-clay PTFE/Sr Low dielectriclosspolytetrafluoroethylene/TeO Structure andmicrowavedielectricpropertiesSr Microwave dielectricpropertiesofSr Glass-Free Zn 27(8-9):3039-3044;2007 Journal oftheEuropeanCeramicSociety 2 Ce 2 Ti 5 2 O Te 16 3 polymerceramiccompositesforelectronicpackagingapplications O 8 microwaveceramicforLTCC applications 2 Ce 2 Ti 5 O 16 ceramics 2 polymerceramiccomposites 2+n Ce 2 Ti 5+n O 15+3n ( n <-10)homologousseries ANNUAL REPORT 2007-2008 133 133 : A comparative study 3 )O employing solid-state fermentation 2/3 )Ta 1/3 Aspergillus oryzae -phenylenevinylene)-gold nanoparticle tapes nanoparticle -phenylenevinylene)-gold p Angewandte Chemie International Ed 46(11):1825-1828;3 Mar 2007 Cerium (IV) ammonium nitrate - A versatile single-electron oxidant Chemical Reviews 107(5):1862-1891;May 2007 Effect of Mg on the fracture characteristics of cast Al-7Si-Mg alloys Materials Science and Engineering A 2007 445-446:405-414;15 Feb J) and SCHENNING (A P H J) (A), MESKERS (S C AJAYAGHOSH hybrid oligo( Self-assembled A simple and efficient strategy towards eleven-membered carbocycles via novel synthetic A simple and efficient strategy towards transformations of pentafulvenes European Journal of Organic Chemistry (35):5847-5851;Dec 2007 Alpha Amylase production by Melt rheology and extrudate morphology studies of polystyrene/polybutadiene blends Melt rheology and extrudate morphology in the presence and absence of compatibilisers Journal of Materials Science 42(6):2054-2063;Mar 2007 SANTHOSHKUMAR (T R) SANTHOSHKUMAR apoptosis in colon cancer cells Pinocembrin triggers bax-dependent Mitochondrial Molecular Carcinogenesis 46(3):231-241;Mar 2007 Journal of Scientific & Industrial Research 66(8):621-626;Aug 2007 Electrostatic potential minimum of the aromatic ring as a measure of substituent constant minimum of the aromatic ring as a Electrostatic potential Chemistry A Journal of Physical 2007 111(4):710-714;1 Feb derived from Bis(phenylazo)stilbene: A DFTRearrangement of 1,3-dipolar cycloadducts level mechanistic investigation Journal of Organic Chemistry 72(2):367-375;19 Jan 2007 Solid state and solution synthesis of Ba(Mg Solid state and solution Materials Research Bulletin Oct 2007 42(10):1831-1844;02 193 NAIR (G) and ANI DEEPTHI VIJAY 192SUBI J GEORGE, VOS (M R J), SOMMERDIJK (N A J M), HERRIKHUYZEN (J), VAN 191 (B C) (K) and PAI (K), PILLAI (U T S), RAGHUKANDAN THIRUGNANAM (A), SUKUMARAN 190(K V) KRISHNAN (K), JINESH (M K), RANI (R), SURESH (E) and RADHAKRISHNAN SYAM 189 (A) SOCCOL (C R) and PANDEY (G), NAMPOOTHIRI (K M), SWETHA (S), DHANYA 188 SUSAN JOSEPH, MENON (A R R), AJU JOSEPH and SABU THOMAS 187 (P S), JOHN MOHAN and (M A), MANGALAM S NAIR, HEMA SURESH KUMAR 186 SURESH (C H), RAMAIAH (D) and GEORGE (M V) 185 SURESH (C H) and GADRE (S R) 184 C R) and MANOJ RAAMA VARMA (P SURENDRAN (K P), VARMA Sl No Description NATIONAL INSTITUTE OF INTERDISCIPLINARY SCIENCE & TECHNOLOGY Thiruvananthapuram 134 134 0 VIJAY NAIR(G),REMADEVI(B),ABHILASH NPILLAIandPAUL (RR) 202 VIJAY NAIR(G), SREEKUMAR (V),MANOJKUMAR (P),SURESH(E)andVIJI(S) 201 VIJAY NAIR(G),SMITHACMATHEW, BIJU(AT)andSURESH(E) 200 VIJAY NAIR(G),SMITHACMATHEW, BIJU(AT)andSURESH(E) 199 198VIJAY NAIR(G),MOHANAN(K),SUJA(TD)andBIJU(AT) VIJAY NAIR(G),DEVIPRIYA (S)andSURESH (E) 197 VIJAY NAIR(G),BIJU(AT)andSMITHACMATHEW 196 VIJAY NAIR(G),ABHILASH(KG),BIJU(AT)andSURESH(E) 195 VIJAY NAIR(G)andSUJA(TD) 194 Description No Sl Heterocycles 73:249-254;2007 Heterocycles n-Tosyliminesand arylidenemalononitriles with Zwitterion Benzothiazole-DMAD A facilesynthesisofThiaaza-andThiadiazafluorenederivatives involving (20):3195-3200;16 Oct2007 Synthesis -Stuttgart 4,5,5-Trisubstitutedy-Butyrolactones N-heterocyclic carbenecatalyzedreactionofenalsandDiaryl-1,2 dionesviahomoenolate:Synthesisof 46(12):2070-2073;12 Mar2007 Angewandte ChemieInternationalEd for thesynthesisofpyrazolineandpyrazolopyridazinederivatives A novelreactionofthe“HuisgenZwitterion”withchalconesanddienones:Anefficientstrategy 48(51):9018-9020;17 Dec2007 Tetrahedron Letters of acylcarbamates Reaction ofTPP-azodicarboxylate zwitterionsandarylaldehydes:unprecedentedsynthesis (8):1179-1184;18 Apr2007 Synthesis -Stuttgart (IV) ammoniumnitratemediatedradicalcyclizationofcinnamamides Stereoselective synthesisof3,4-trans-disubstitutedgamma-lactamsbycerium 48(21):3667-3670;21 May2007 Tetrahedron Letters cycloaddition involvingaquinoline-DMADzwitterionandcarbonylcompounds Efficient synthesisof[1,3]oxazino[2,3- (5):697-704;1 Mar2007 Synthesis -Stuttgart protocol forcarbon-nitrogenbondformation The reactionofHuisgenzwitterionwithdiaryl-1,2-dionesandketones:Anefficient (12):1833-1836;18 Jun2007 Synthesis -Stuttgart Efficient higher-order cycloadditionreactionsof8,8-dicyanoheptafulvenewithdienes 63(50):12247-12275;10 Dec2007 Tetrahedron Intramolecular 1,3-dipolarcycloadditionreactionsintargetedsyntheses(Tetrahedron ReportNo.817) a ]quinoline derivativesbyanovel1,4-dipolar ANNUAL REPORT 2007-2008 135 135 + Ion binding 2 in the BCScritical framework with emphasis on extrinsic effects on 2 superconductors for magnet application (Topical Review) magnet application (Topical superconductors for 2 31 Jul 2007 Organic Letters 9(10):1999-2002;10 May 2007 Superconductor Science and Technology Superconductor Science 20(1):R1-R13;Jan 2007 Self-organization of phenyleneethynylene into wire-like molecular materials on surfaces of phenyleneethynylene into wire-like Self-organization Journal of Physical Chemistry C: Letters 111(41):14933-14936;2007 In situ synthesis of metal nanoparticles and selective naked-eye detection of lead ions from In situ synthesis of metal nanoparticles and selective naked-eye detection of media aqueous Journal of Physical Chemistry C: Letters 111(34):12839-12847;30 Aug 2007 Metallo supramolecular assemblies of Bis-squaraines by allosteric Ca Metallo supramolecular assemblies of Superconductivity of MgB inclusion and topographical analysis of non-covalently imprinted polymer Fabrication pinacolyl methylphosphonate - A simulant of Soman membranes for the selective sensing of Electrochimica Acta 52(24):6922-6928;01 Aug 2007 Flux pinning properties of magnesium diboride added (Bi,Pb)-2212 superconductors (Bi,Pb)-2212 added diboride magnesium of properties pinning Flux Journal of Alloys and Compounds 439(1-2):L1-L4; Prospects for MgB GEORGE THOMAS (K) GEORGE THOMAS charge quantum dots using photoinduced the shell thickness of core-shell An approach for optimizing transfer Chemistry C - Letters Journal of Physical Jul 2007 111(28):10146-10149;19 temperature (Topical Review) temperature (Topical Superconductor Science and Technology 20(10):R31-R45;Oct 2007 The titles at Sl nos. 16, 28, 117, 203, 209 & 210 are covered in Web of Science, Science Citation Index Expanded, but the journals being new, no IF has been assigned for Reports Sc Ed 2006. the Current year in the Journal Citation NB: 210 (K), JAMES (P V), RAMESH (A R), SURESH (C H) and GEORGE THOMAS (K) YOOSAF 209 (K) (K), IPE (B I), SURESH (C H) and GEORGE THOMAS YOOSAF 208YAGI (S), HYODO (Y), HIROSE (M), NAKAZUMI (H), SAKURAI (Y) and AJAYAGHOSH (A) (Y) and AJAYAGHOSH (M), NAKAZUMI (H), SAKURAI (Y), HIROSE (S), HYODO 208YAGI 207 (K P), NAIDU (G R K) and PRASADA RAO (T) PRATHISH (V), VISHNUVARDHAN 206 (U) and SYAMAPRASAD VINOD (K), NESON VARGHESE 205 (U) (R G), BIJU (A), SARUN (P M), and SYAMAPRASAD VINOD (K), ABHILASH KUMAR 204 (U) SYAMAPRASAD (R G) and (K), ABHILASH KUMAR VINOD 203V NAIR, RAMAMURTHY (P) and (T), PRATHEESH (R), SHANMUGAPRIYA VINAYAKAN Sl No Description NATIONAL INSTITUTE OF INTERDISCIPLINARY SCIENCE & TECHNOLOGY Thiruvananthapuram 136 136 0PILLAI (RM) 10 PAWELS (R),AJITHARIDASandJOSE(BT) 9 8OMANAKUTTY (M)andNISHA(VP) OMANAKUTTY (M)andBEENAJOY 7 OMANAKUTTY (M) 6 OMANAKUTTY (M) 5 NIRMALAMENON (A) 4 CARVALHO (JC),OISHI(BO),WOICIECHOWSKI(AL),PANDEY (A),BABITHA(S)and 3 25(3):30-34;Dec2007 ANANTHAKUMAR(S) 2 4(1):1-11;2007 AKHILARAJANandEMILIAABRAHAM(T) 1 Description No Sl titles Non-SCI 29(2):78-80;Apr-Jun2007 Journal ofMedicinalandAromaticPlantSciences from Kerala MET News MET 181(3648):298-301;Oct 2007 181(3648):298-301;Oct Foundry Trade Journal HIPing -apotentpostcasting treatmentforhighintegrityaluminiumcastings(Technical Paper) 49(1):17-21;2007 Journal ofEnvironmentalScience&Engineering Activity testforbiologicalsulfatereduction 2007 20(10):25-26;Oct India Spice Enhancement ofcapsaicincontentchillibycoldgrinding technique 10(6):490-493;2007 Journal ofEssentialOilBearingPlants A studyontheretentionoffreshflavourcardamomoilbycoldgrinding 2007 20(5):4-5;May India Spice Medicinal propertiesofCurryleaf 20(1):10-11;Jan 2007 India Spice Medicinal properties of Cardamom Chemical compositionoftheessentialoilfromleavesandrootsginger( 6(2):194-199;Apr 2007 Indian JournalofBiotechnology and pigmentextractionusingdifferentsolvents. Effect ofsubstratesontheproduction SOCCOL (CR) Ti Fibers Natural of Journal Coir Fiber-Processandopportunities:Part 2 3 SiC 2 ceramics-Apotentialmatrixforhightemperatureelectroconductive Monascus biopigmentsbysolid-statefermentation Zingiber officinale Zingiber ) ANNUAL REPORT 2007-2008 137 137 Minerological studies on beach sediments of South East Coast, India MET News 25(3):44-50;Dec 2007 Squeeze casting: An overview MET News 25(3):7-14;Dec 2007 Assessment of computational models for laminated composite plates International Journal of Computational Methods 4(4):633-644;Dec 2007 the formation of Structure - directing effect of renewable resource based amphiphilic dopants on conducting polyaniline-clay nanocomposite Symposia Macromolecular 254(1):274-283;Aug 2007 KAMACHI MUDALI (U) and PAI (B C) KAMACHI MUDALI (U) and PAI behaviour of AZ91 magnesium alloy for automotive Improved mechanical properties and corrosion applications Indian Foundry Journal 53(7):27-32;Jul 2007 Microstructure and mechanical properties of low pressure cast AZ91 magnesium alloy Microstructure and mechanical properties and Materials Properties International Journal of Microstructure 2(3/4):429-439;2007 Materials Informatics MET News 25(3):35-40;Dec 2007 Nano flowers - the beauty of small MET News 25(3):41-43;Dec 2007 Prospects of functionally graded materials for engineering applications graded materials for engineering Prospects of functionally MET News 25(3):19-29;Dec 2007 Centifugal casting: A potential technique formaking functionally graded materials and A potential technique formaking functionally Centifugal casting: paper) (Technical engineering components Indian Foundry Journal 53(6):79-87;Jun 2007 20 SUNDARARAJAN (M) and USHA NATESAN 19 (B C) (K), PILLAI (R M), PILLAI (S G K) and PAI SUKUMARAN 18SUDHA (J D) and REENA (V L) 17 PRAKASH (V) (S) and SYAM SUBHA (K), SHASHIDHARAN, SAVITHRI 16 (S), (J), NINGSHEN (A), PILLAI (U T S), SWAMINATHAN SRINIVASAN 15 (B C) PILLAI (U T S) and PAI (A), SRINIVASAN 14 (V M) SREEKUMAR 13 S) (S SREEJA KUMARI 12 (B C) and PAI RAJAN (T P D), PILLAI (R M) 11 (B C) and PAI RAJAN (T P D), PILLAI (R M) Sl No Description NATIONAL INSTITUTE OF INTERDISCIPLINARY SCIENCE & TECHNOLOGY Thiruvananthapuram 138 138 r Ms .SskmrUAG pnoe rjc 30-0724-10-2007 13-09-2007 19-09-2007 01-09-2007 15-09-2007 2007 Dioxin on Conference Internatl. 30-03-2008 01-09-2007 15-03-2008 project sponsored GE project Collaborative DST-Argentina Japan Argentina program DST-JSPSExchange USA 23-07-2007 Dr.- Japan Sukumaran K Rajeev 20-06-2007 01-01-2007 Dr.Sasikumar R. (Mrs) Conference International Chemtech 03-09-2007 Dr.Anbu M. GermanyTechnicalUniversity, Lanka Sri Dresden 31-07-2007 ChemistryWorld Italy41st Dr.Das Suresh 14-08-2007 27-06-2007 08-08-2007 Dr.Sudha D. J. Mrs. Chandrashekar TK Prof. Congress Tsukuba,Osaka and Himeji Dr.Pai C. B. Japan 28-05-1007 14-05-2007 24-04-2007 23-04-2007 ToProject ItalyDST-MFACollaborative Dr.Ajayaghosh A. From Meeting Scociety Royal The Dr.Thomas George 28-03-2007 10-03-2007 28-04-2007 27-03-2007 UK project collaborative DST-SeCyT Purpose Argentina project IFCPAR-Collaborative Dr.Pandey Ashok France Country Dr.Singh K. Sudheer Dr.Nampoothiri K.M. Scientist Name GENERAL INFORMATION Hong Kong Hong 14-02-2008 01-02-2008 26-09-2007 12-09-2007 19-10-2007 16-10-2007 project DST-JSPSCollaborative 29-12-2007 25-12-2007 Japan 2007 React and IFCOS Conference Aquintaine Germany 08-08-2007 France& 11-06-2007 24-02-2008 Meeting France Indo-China 22-02-2008 China conference Editors Elsevier 14-09-2007 12-09-2007 Singapore 28-04-2007 Fellowship UBF Conference International Korea Bio 26-04-2007 22-04-2008 Korea South 27-03-2008 France Symposium Internatl. KSBB-07 Korea South Programme Indo-French France VISITS ABROAD ANNUAL REPORT 2007-2008 139 139 ‘Best Poster Award’ ICAMC 2007 ‘Best Poster Appreciation Award, Federal University of Parana, Brazil University of Parana, Appreciation Award, Federal by IANCAS, BARC- 2006 UK-2007 2.Medal 2007 MRSI Bangalore (2008) of Blaise Pascal-2007 Univ. From HONOURS AND AWARDS HONOURS et al. Satyajith ShuklaK.G.K. Warrier Award’ ICS-71 ‘Best Poster Rajesh Komban Rajesh Komban K Padmanabhan N. Balasubramani, K.R. Ravi, Pillai & B.C. PaiU.T.S. Award’ (Posters) Paper ‘Best Technical ICAMC 2007 U.T.S. Pillai & B.C. Pai, Pillai & B.C. U.T.S. K. Sukumaran, K.K. Ravikumar,2007 - ATM – II prize) - IIM - NMD Antony (Poster S.G.K. Pillai & V. category Award’ in the Non-Ferrous ‘Best Poster Rajan,Joby Joseph, T.P.D. R.M. Pillai, B.C. Pai, Suryanarayanan & V. Award’ Paper ‘Best Technical -2007 ICAMC Dr. M. JayakannanDr. Mary GladisDr.J. D.B. Ambili Raj Scientist Award (Chemical Sci.) – 2007 CSIR Young Reeta Rani SinghaniaAward” Best Thesis “Prof.H.J.Arnikar Award on Biofuels by Elsevier Science, Best Paper Chennai- 2007 IIT, S.Biju &M. Suresh, S.B. Shiju,A. Srinivasan, J. Swaminathan, 2007 IIM - NMD - ATM (Oral-I prize)- Second prize for the poster Presentation, MTIC-XII) Award’ in the Metal Sciences - I category ‘Best Paper Dr Suresh Das K. George ThomasDr. of Indian Academy of Sciences, Elected as the Fellow 2007 Medal MRSI Prof. T.K. Chandrashekar T.K. Prof. A. AjayaghoshDr. Doctorate Degree Medal - 2008 CRSI Silver 1. Prize (Chemical Sci.) -2007 Shanti Swarup Bhatnagar PandeyHonorary Ashok Dr. NATIONAL INSTITUTE OF INTERDISCIPLINARY SCIENCE & TECHNOLOGY Thiruvananthapuram 140 140 eiVrhs efasml flnal -ojgtdD.A jygohKerala Dr. Ajayaghosh A. Self-assembly oflinearlyp-conjugated Kerala Dr.Reji Varghese SureshDas PhotoactiveMesogenicsugars: Synthesis, Kerala Kerala Dr.Narayanan G. SureshDas Dr. SureshDas Kerala synthesis,photophysicalandliquid N. S.SaleeshKumar Designandsynthesisofsomenovel Dr. SureshDas Kerala M. C.Basheer Synthesisandstudiesofnoveldonor- Dr. D.Ramaiah Shibu Abraham DesignofQuinolinebasedSquaraine Kerala Kerala Kuthanapillil Dr.T.Prasada Rao Jyothish Dr. D.Ramaiah Biomimeticpolymermaterialsforthe Synthesisandstudyofinteractions CUSAT Elizabeth Kuruvilla Dr. M.L.P.Reddy University Vanadophilic heterocyclicß-diketone: R. Kala Supervisor Kerala P.N. Dr. K.R.Gopidas Remya Sri Dr. M.L.P.Reddy Photoinducedelectrontransfer in K. JanardhanReddyStudiesonliquid-liquidextractionof CUSAT ThesisTitle Bijitha Balan Dr. P. Prema Productionofalkalineendo-xylanaseby C Ashapoorna Kerala Dr. M.T. Sebastian TheA(B11/2B"1/2)O3[A=Ba,Ca,Sr, Mg; L. AbdulKhalam Student p-Phenyleneethynylenes molecules: p-Phenylenevinylenesversus properties liquid crystallineandphotochemical Butadiene basedMesogens crystalline propertiesofsome sensitizers andprobes Squaraine basednearinfrared acceptor-subtituted Butadienesystems properties photophysical andphotobiological University Synthesis andstudyoftheir dyes forphotodynamictherapy: strand anddoubleDNA novel Acridiniumderivativeswithsingle of lanthanides preconcentrative seperationorsensing complexation Synthesis, characterizationand heterocyclic b-diketonates zirconium andhafniumwith systems Cyclodextrin baseddonor-acceptor of paperpulps application forbiobleaching solid-state fermentationandits ceramics forwirelesscommunications B'=RE andB"=Nb,Ta] microwave Ph.D. DEGREEAWARDEDPh.D. Venkateswara ANNUAL REPORT 2007-2008 141 141 Thomas intermediates and related chemistry and dialkylazodicarboxylate with carbonyl compounds of Al-7Si-0.3Mg alloy Al-7Si-0.3Mg of carbon and carbon-heteroatom bond forming reactions heteroarylmethanes and biphenyl derivatives heteroatom bond forming reactions mediated by N-heterocyclic carbenes constructions mediated by1,4-dipolar molecular systems related chemistry rare earth modified (Bi,Pb)-2212 superconductors structure and propertiesB.C. Pai Dr. donor scaffolds a few oligo (p-Phenylenevinylene) of Chromophore derivatives: Control properties of assemblies and optical p-organogels of phenyleneethynylene based Thomas p-gels: Modulation of optical properties p-gels: Modulation excitation energy and application as andtowards fused ring cyclooctanoids Radhakrishnan Smitha C Mathew Novel reactions of triphenylphosphine G. Vijay Nair Dr. Kerala Abhilash, N.. Engaging Zwitterions in novel carbon-Vidya, N. G. Vijay Nair Dr. V.Sreekumar, Kerala for the synthesis of tris- Novel strategies G. Vijay Nair Dr. and carbon- Novel carbon-carbon B. Rema Devi Kerala G. Vijay Nair Dr. Novel heterocyclic constructions Kerala G. Vijay Nair Dr. Kerala S.T. Shibu JosephS.T. Plasmon coupling in gold nanorods K. George Dr. A. Biju Kerala Rajesh KombanS.S. Sreeja Kumari Structural and transport properties of of alloying additions on the Influence U. Syamaprasad Dr. R.M. Pillai & Kerala Dr. CUSAT K.G.K. Warrier Dr. Kerala C. Vijayakumar of self-assembly Design synthesis and A. Ajayaghosh Dr. James V. P. Kerala Synthesis and photophysical properties K. George Dr. Kerala Student K. PraveenV. derived(p-phenylenevinylene) Oligo A. Ajayaghosh Dr. Kerala Thesis Title Supervisor University K. Syam Krishnan utilization of pentafulvenes Synthetic K.V. Dr. Kerala NATIONAL INSTITUTE OF INTERDISCIPLINARY SCIENCE & TECHNOLOGY Thiruvananthapuram 142 142 ANNUAL REPORT 2007-2008 143 143 Dr. Naresh Kumar Naresh Dr. Head R & D Planning Division, CSIR, Rafi Marg, New Delhi - 110 001 A. Sundaresan Dr. Scientist Agroprocessing & Natural Products Division (NIST) National Institute for Interdisciplinary Science & Technology 019 Trivandrum-695 Dr. S.L. Govindwar Dr. Adviser Department of Biotechnology CGO Complex, Lodhi Road, New Delhi - 110 003 Block-2, 7th Floor, M.G. Kulkarni Dr. Science & Engineering Head, Polymer Road, Pune - 411 008 National Chemical Laboratory, Pashan B.K. Mishra Prof. Director Bhubaneswar - 751 013 Institute of Minerals and Materials Technology, Chandrashekar T.K. Prof. Director (NIST) National Institute for Interdisciplinary Science & Technology - 695 019 Trivandrum Prof. S. Ramakrishnan, FASc S. Ramakrishnan, Prof. Professor Department of Inorganic & Physical Chemistry 560 012 Indian Institute of Science, Bangalore - Pradeep Dr. Senior Scientist Research Development & Design Centre Tata - 411 013 54B, Hadapsar Industrial Estate, Pune Khakhar D.V. Prof. Professor Department of Chemical Engineering Mumbai - 400 076 Powai, Indian Institute of Technology, Chief Controller R & D (AMS) & D.S Chief Controller R & Bhawan Room No. 301, DRDO 110 011 Organisation, New Delhi - Defence Research Development Sharma Ashutosh Prof. Engineering Department of Chemical Professor, Kanpur - 208 016 Indian Institute of Technology, K.S. Gandhi Prof. Engineering Department of Chemical Professor, 560 012 Indian Institute of Science, Bangalore - M. Radhakrishna Pillai, FASc Dr. Director - 695 019 Trivandrum Jagathy, Rajiv Gandhi Centre for Biotechnology, Dr. Dipankar Banerjee Dipankar Dr. MEMBERS OF THE RESEARCH COUNCIL (Apr' 2007 - Mar' 2010) 2007 - Mar' (Apr' RESEARCH COUNCIL OF THE MEMBERS SECRETARY: MEMBERS: CHAIRMAN: NATIONAL INSTITUTE OF INTERDISCIPLINARY SCIENCE & TECHNOLOGY Thiruvananthapuram 144 144 MEMBER-SECRETARY: (Period: 01.07.2005to30.06.2007) ManagamentCouncil the of Members MEMBERS: CHAIRMAN: (Period: From 01-07-2007) MEMBER-SECRETARY: MEMBERS: CHAIRMAN: COFA, Dr. Gupta, A.K. Shri K.Prasad, Dr. C.S.Bhat, Dr. (Mrs.)S.Savithri, Dr. K.MadhavanNamboothiri, Dr. U.T.S. Pillai, Dr. SureshDas, Prof. T.K. Chandrashekar, COA/AO, COFA, Dr. GaneshPandey, Shri P. Guruswamy, Dr. (Mrs.)AshaJayakannan, Dr. (Mrs.)ElizabethJacob, Dr. Sundaresan, A. Dr. U.Syamaprasad, Dr. B.C.Pai, Prof. T.K. Chandrashekar, COA/AO, NIIST NIIST NIIST NIIS Scientist, NIIST Scientist, T Scientist, NIIST Scientist, Technical Officer, NIIST Scientist, NPL,NewDelhi Scientist, NIIST Scientist, Scientist, NIIST Scientist, Scientist,NCL,Pune Scientist, NIIST Scientist, Technical Officer, NIIST Scientist, NIIST Scientist, NIIST Scientist, Director, NIIST Director, NIIST Scientist, NIIST Scientist, NIIST Scientist, NIIST ANNUAL REPORT 2007-2008 145 145 Strength As on 01-04-2007 STAFF LIST OF SCIENTISTS/OFFICERS Dr C Arumughan, Scientist G (Retired, 30/09/2007) Dr A Sunderesan, Scientist F (Head) Smt B Sankarikutty Amma, Scientist F (Retired, 31/08/2007) Scientist F Sri M M Sreekumar, Scientist EII Dr (Mrs) M A Sumathykutty, Dr N Gopalakrishnan, Scientist EII Sri Thomas Samuel, Scientist EII Dr C Balachandran, Scientist EII Smt A Nirmala Menon, Scientist EII Smt Omanakutty Amma, Scientist EI Prof T K Chandrashekar, Director Agro-processing & Natural Products Division Others BTotal A + BTotal 2 256 76 222 2 60 Group AGroup BGroup CGroup D 3 31 17 23 2 27 15 14 Group IOthers ATotal B. ADMINISTRATIVE 10 180 10 162 A. SCIENTIFIC /TECHNICAL Group IVGroup IIIGroup II 100 35 35 85 34 33 Particulars Sanctioned Number in position NATIONAL INSTITUTE OF INTERDISCIPLINARY SCIENCE & TECHNOLOGY Thiruvananthapuram 146 146 Dr (Mrs)JDSudha,Technical OfficerC Dr VGAnand,ScientistC(Resigned22/06/2007) Dr (Mrs)SKAsha,ScientistC(Transferred 14/12/2007) Dr MJayakannan,ScientistC(Resigned14/12/2007) Dr KVRadhakrishnan,ScientistC Dr ASrinivasan,ScientistEI Sri PShanmugham,ScientistEI Dr (Mrs)RLuxmiVarma, ScientistEII Dr KGeorgeThomas,ScientistEII Dr DRamaiah,ScientistEII Dr KRGopidas,ScientistF Dr Ajayaghosh,ScientistF Dr MLakshmipathyReddy, ScientistF Dr (Mrs)TEmiliaAbraham,ScientistF Dr (Mrs)MangalamSNair, ScientistF Dr (Mrs)AJayalakshmi,ScientistF Dr (Mrs)Sathychandrasekhar, ScientistF Dr TPrasadaRao,ScientistG Dr SureshDas,ScientistG(Head) Chemical Sciences&TechnologyDivision Dr (Mrs)BVijayalakshmiAmma,Technical OfficerE1 Miss DSSuganya,ScientistB Dr RajeevkumarSukumaran,ScientistB Dr SudheerKumar Singh,ScientistB(Transferred 19/03/2008) Dr KMadhavanNampoothiri,ScientistEI Dr (Mrs)PPrema,ScientistF Dr AshokPandey, ScientistF(Head) Biotechnology Division Smt LPrasannaKumari, Technical OfficerB Dr (Mrs)BeenaJoy,Technical OfficerC Sri RBabu,Technical OfficerE1 Sri PJayamurthy, ScientistB Dr PNisha,ScientistB Ms MVReshma,ScientistB Sri VVenugopalan, ScientistC Dr (Mrs)KPPadmakumari Amma,ScientistC Dr PNMohandas,Scientist G Dr KGWarrier, ScientistG(Head) Dr RMPillai,ScientistG(Head) Materials &MineralsDivision ANNUAL REPORT 2007-2008 147 147 Process Engineering & Environmental Technology Dr P P Thomas, Scientist G (Head) Sri Ajit Haridas, Scientist F F Scientist Dr (Mrs) Roschen Sasikumar, Sri P Raghavan, Scientist F Smt Elizabeth Jacob, Scientist EII Sri J Ansari, Scientist EII Dr (Mrs) S Savithri, Scientist EII Dr Peter Koshy, Scientist G Scientist Koshy, Dr Peter Scientist G Dr C Pavithran, Scientist G Dr U Syamaprasad, Scientist G Dr M T Sebastian, Scientist F Sri K Harikrishna Bhat, F Dr Jose James, Scientist EII Dr V John, Scientist Scientist EII Dr A R R Menon, EII Sri M C Shaji, Scientist Scientist EII Dr P Prabhakar Rao, Sri K Sukumaran, Scientist EII Dr U T S Pillai, Scientist EII Ghosh, Scientist EII Dr Swapan Kumar Scientist EII Dr Manoj Raama Varma, Dr M Ravi, Scientist EII Scientist EI (Retired 31/01/2008) Dr K Ravindran Nair, Scientist EI Sri S Ananthakumar, Sri P Krishna Pillai, Scientist EI Dr T P D Rajan, Scientist C Dr S V Shukla, Scientist C 11/10/2007) B (Transferred Shukla, Scientist Dr Sanjeev Kumar Sri M Sundararajan, Scientist B 29/06/2007) Ms Aparna Mondal, Scientist B (Resigned Officer E1 Sri S G K Pillai, Technical Officer E1 Janaki, Technical Smt M E Kochu Officer E1 Sri P Mukundan, Technical Officer E1 Technical Sri S Velusamy, Officer C Dr V S Prasad, Technical Officer C Technical Sri Brahma Kumar, Officer C Technical Sri K K Ravikumar, C Officer Sri M Chandrasekharan, Technical Officer C Technical Sri P Perumal, Officer B Sri P Gurusami, Technical Officer A Sri M R Chandran, Technical NATIONAL INSTITUTE OF INTERDISCIPLINARY SCIENCE & TECHNOLOGY Thiruvananthapuram 148 148 Sri ChandraBabu,AEE(Civil) Sri KVOonnikrishnan,AEE Sri KPrasad,AE Sri RRajeev, EE(Telephones) Sri VPThomas,ScientistF(Head) Civil EngineeringandEstateManagement Smt SMini,Technical OfficerC Sri MRamasamyPillai,Technical OfficerC Sri VMoni,ScientistB Sri NithiyananthaVasagam, ScientistB Smt SantoshBabu,ScientistEI(Head) Library &Informatics Dr MSankaranarayanan,Technical OfficerC Sri RSPraveenRaj,ScientistB Sri DBheemeswar, ScientistEI Dr VGMohananNair, ScientistEII Dr CChandrasekaraBhat,ScientistEII Sri SSureshKumar, ScientistF(Head, PME) Dr BCPai, ScientistG(Head,BD) Planning &BusinessDevelopment Smt VijayaPrasad,Technical OfficerB Dr BKrishnakumar, ScientistB Sri PAnand,ScientistB(Transferred 25/10/2007) Dr CHSuresh,Scientist Dr MAnbu,ScientistEI Dr VBManilal,ScientistEI Dr (Mrs)RugminiSukumar, ScientistEI Sri KDamodaranPillai,Security Officer(Retired,31/01/2008) Smt SaradaNair, PrivateSecretary Sri RNaraynaPillai,PrivateSecretary(Retired31/10/2007) Sri AVThomas,SO(F&A) Smt PVViji,SO(F&A) Smt SSobhana,SO Sri MRDevasis,SPO(Adhoc) Sri DPMaret,FAO (Tranferred 15/02/2008) Sri NSRaju,AO Sri TVSankaran,COFA Administration ANNUAL REPORT 2007-2008 149 149 National Technology Day lecture by Dr. G.S. Bhuvaneshwar Day lecture by Dr. National Technology laboratory to Industry transformation of heart valves developed by SCT to the contributions the to SCT by developed valves heart of transformation Industry to laboratory CSIR Day Foundation was celebrated as an open day in the morning followed by Foundation National Technology National Day Technology to commemorate the triple success of Indian technologies namely, CSIR Foundation Day CSIR Foundation universities and colleges from students 300 About 2007. September 26th on afternoon the in Lecture Day being activities D & R major and general in CSIR about introduction brief a With Laboratory. the visited students. the for arranged was society the to CSIR of contribution the on show video a NIIST, at pursued This was followed by a presentation of major contributions of NIIST and ongoing R & D programmes various to taken and batches different into grouped later were Students thereon. available facilities and laboratories such as Polymer, Agro Processing, XRD/AFM/NMR facility, Photochemistry, environment of various organizations. Dr. B. C. Pai, in his presidential address emphasized the importance of observing of importance the emphasized address presidential his in Pai, C. B. Dr. organizations. various of the Technology Day as mark of achievements of our maturity in technology in areas such defense as and space, atomic energy. He called upon the members to rededicate for the cause of technocrats and industries. technologies by pooling together expertise of scientists, technologists, developing presentation on the development of Heart Valves and their clinical trials, Dr. Bhuvaneshwar attributed Bhuvaneshwar Dr. trials, clinical their and Valves Heart of development the on presentation of success the Inaugural flight of Hamsa, Successful flight of prithivi missile and Sensational Nuclear test at Pokhran at test Nuclear Sensational and missile prithivi of flight Successful Hamsa, of flight Inaugural was celebrated on May 11, 2007. National Technology Day Lecture was delivered by Dr. Head, Wing, Biomedical G.S. Sri Bhuvaneshwar, Technology Chitra Tirunal Institute for Medical Science & contribution of synergisticeffect the highlighted Bhuvaneshwar Dr. lecture his In Trivandrum. Technology, technical the In technology. any of development successful the for technocrats technicians, scientists, of National Technology Day Celebration Day Technology National NATIONAL INSTITUTE OF INTERDISCIPLINARY SCIENCE & TECHNOLOGY Thiruvananthapuram 150 150 Recruitment & Assessment Board, CSIR & Former Secretary, Department of Science & Technology, New Chairman, Ramamurthy, V.S. Prof. NIIST. Director, Chandrashekar, K. T. Prof. by over presided was of artscientificinstrumentsandR&Dproductoutcomes. taken to various laboratories to witness experimental demonstrations using advanced techniques, state R & D programmes and facilities available thereon, students were grouped into different batches and arranged for the students. After a power point presentation on major contributions of NIIST, ongoing were society the to CSIR of contributions the on show video a and NIIST at pursued being activities D & R major general, in CSIR about introduction Brief day. open an as observed was which forenoon the during Laboratory the visited universities and colleges from students of number large A 2007. NIIST Foundation Day year fromtheservicesofCSIR. with a memento. The chief guest also felicitated the staff members who have felicitated retired were during CSIR the in preceding service of years 25 completed have who members staff The scientists. NIIST S. S. Bhatnagar prize for chemical of Sciences for the second time winning in a row and young of CSIR scientist award by news the announced also He breakthrough. major registered had laboratory the which in programmes D R& major the of overview a presented palm, also oil He as etc., ilmenite such coconut, region the of resources natural the to addition value of areas the in laboratory the of contributions various the briefed address, presidential his Chandrashekar,in Prof. added. be India is likely to attain No. 4 in GDP, become 2 trillion economy and when about 200 GW energy is to whereby 2020 by explode to bound field a is science Material countries. developed/developing the research, off shoring industrial R&D, foreign investment in R&D and forging of strategic alliances with He furthersuggestedthatinascenarioofglobalizationoneshouldpayattentiontonewfrontiers need ofeducationandresearchwhichplayakeyroleinachievingSuperPower statustothecountry. the emphasized Ranganathan Prof. Research” Materials of “Globalization topic theme a On nature. in interdisciplinary are which of both research applied and science basic of importance the signifies Ranganathan in his address first complimented the Institute for having aptly selected new name which was the chief guest. The function was presided over by Prof. T. K. Chandrashekar, Director, NIIST. Prof. Prof. S. Ranganathan, INAE Distinguished Professor & Honorary Professor, IISc, NIAS & JNCASR, Bangalore using advancedtechniques,stateofartscientificinstruments. demonstrations experimental witness to laboratory processing Clay technology,Engineering, Process NIIST Foundation Day Lecture and felicitation of the staff members arranged in the afternoon NIIST,as renamed being after first the FoundationDay, NIIST October,6th on celebrated was CSIR Foundation Day Lecture and felicitation of the staff members was arranged in the afternoon. ANNUAL REPORT 2007-2008 151 151 NIIST Foundation Day lecture by Prof. V.S. Ramamurthy V.S. NIIST Foundation Day lecture by Prof. Five scientists selected for the outstanding R&D performance award for the year 2006-07 were 2006-07 year the for award performance R&D outstanding the for selected scientists Five felicitated by the chief guest. The staff members selected from the and service certificate a with departments guest chief the and by felicitated also R& were awards appreciation D the for departments memento. Delhi was the chief guest who delivered the Foundation Day lecture entitled ”Knowledge Management”. ”Knowledge entitled lecture Day Foundation the delivered who guest chief the was Delhi of terms in performance outstanding its for NIIST congratulated first Ramamurthy Prof. address his In high impact factor publications and transfer of major technologies in recent years and the greater visibility gained by it in light of 2 prestigious awards such as S. S. Bhatnagar Prize and CSIR Young of importance the highlighted further He 2007. year the in scientists NIIST by bagged award Scientist be treated as an asset, as the generation of knowledge needs knowledge management which should to effort every make and management knowledge imbibe to scientists the upon called He investment. in his Chandrashekar, Prof. assimilate knowledge, transform the knowledge to a saleable commodity. the for significance special assumes year the of day foundation the that informed address presidential laboratory as two of the scientist s have bagged the coveted S.S. Bhatnagar Award for the chemical NIIST. of history the in time first the for award scientist young CSIR and row a in time second Sciences, He also informed that in order to to raise to recognize staff the upon and called He motivate awards. appreciation the with rewarded staff suitably be members would expectations who deliver to the in the years to come. the occasion when the Institution is doing its best to keep it growing NATIONAL INSTITUTE OF INTERDISCIPLINARY SCIENCE & TECHNOLOGY Thiruvananthapuram 152 152 Radhakrishnan Nair, formerDirector,Shri CBIon16thNovember,by 2007. lecture valedictory a and winners the to prizes of distribution the with ended celebrations The participation. wide with conducted were writing slogan and drawing cartoon elocution, on competitions celebration, the Director.of the part by a English As and Hindi in pledge administering after Commissioner Transport IPS, Bhanu, Chandra Ramesh Shri by inaugurated was which 2007 Vigilance AwarenessWeek 2007 The Vigilance Awareness week 2007 was observed in the institute from 12th to 16th November, Vigilance AwarenessWeekInaugurationlecturebyShri.RameshChandraBhanu,IPS, Vigilance AwarenessWeekValedictory Function Shri.RadhakrishnanNair, FormerDirector, CBIdeliveringvaledictorylecture Transport Commissioner, Govt.ofKerala ANNUAL REPORT 2007-2008 153 153 Ú±…“ UÙ…j…… E‰Ú ±…B i…… EÚ… ¥…π…™… l……- ¥…π…™… EÚ… i…… … |…∂……∫… x…EÚ EÚ…™……Á Ú Æ˙…π]≈ı ∫…∆P… ÀΩ˛n˘“ ¶……π…… ÀΩ˛n˘“ ∫…∆P… Æ˙…π]≈ı Ú …V…¶……π…… ÀΩ˛n˘“ EÚ…‰ ¥…∑… EÚ…‰ ÀΩ˛n˘“ …V…¶……π…… =n¬˘P……]ıx… EÚ™……* =xΩ˛…Âx…‰ V…¶……π…… E‰Ú |…S……Æ˙ |…∫……Æ˙ E‰Ú |…∫……Æ˙ |…S……Æ˙ E‰Ú V…¶……π…… Æ˙, x…n‰˘∂…EÚ, Bx… +…<« +…<« +…<« Bx… x…n‰˘∂…EÚ, Æ˙, x…Ω˛” Ω˛…‰i…… Ω˲* =xΩ˛…Âx…‰ +{…x…‰ =xΩ˛…Âx…‰ Ω˲* Ω˛…‰i…… x…Ω˛” EÚÆ˙ ±…™…… Ω˲* +{…x…‰ ¶……π…h… +{…x…‰ Ω˲* ±…™…… EÚÆ˙ n˘ EÚ… ∫…∆ I…{i… ¥…¥…Æ˙h… |…∫i…÷i… ¥…¥…Æ˙h… ∫…∆ I…{i… EÚ… n˘ E‰Ú n˘…ËÆ˙…x… x™…⁄™……E«Ú ®… +…`ˆ¥… ®… x™…⁄™……E«Ú n˘…ËÆ˙…x… E‰Ú ®…±]ı“®…“ b˜™…… i…EÚx……ϱ…V…“ EÚ… i…EÚx……ϱ…V…“ ®…±]ı“®…“ b˜™…… ÀΩ˛n˘“ ]ı{{…h…/+…±…‰J…x… ÀΩ˛n˘“ |…∂x……‰k…Æ˙“ 2007 2. 4. ∫…i…∆§…Æ˙ EÚ…‰ ÀΩ˛n˘“ n˘¥…∫… E‰Ú ∞¸{… ®… i…l…… ®… ∞¸{… E‰Ú n˘¥…∫… ÀΩ˛n˘“ EÚ…‰ ∫…i…∆§…Æ˙ 14 V…÷±……<« 13-15 §…V…‰ ∫…∆{…z… Ω÷˛+…* b˜…Ï. 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