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Table of Contents ����������������������� �������� ������������������������� Table of Contents INTRODUCTION & OVERVIEW 2005-2006 4 HONOURS/AWARDS/APPOINTMENTS 6 Appointments 6 Awards 7 CLINICAL SERVICES 8 Patient Services 8 Clinical Biochemistry 8 Hematopathology & Blood Transfusion 9 Rapid Response Laboratory 9 Pathology 10 Laboratory Genetics 11 Andrology 12 LABORATORY INFORMATICS 13 Laboratory Information System 13 Expanded Interfaces 13 Citrix Support 13 Web Site/Communications 13 Paradigm Document Control System 14 Digital Imaging 14 RENOVATIONS & RELOCATIONS 15 QUALITY PROGRAMS 16 Accreditations, Regulatory Certifications/Registrations 16 External Quality Assessment Programs 17 Continuous Quality Improvement Activities: Indicators 18 Quality Management Team Activities: 2005-2006 18 EDUCATION 19 Educational Activities July 2005 – June 2006 19 Education Committee 19 Medical Education 19 Research Student Programs 24 Technical Education 25 SPONSORED RESEARCH AND INNOVATION 27 PRESENTATIONS & ABSTRACTS July 1, 2005 – June 30, 2006 32 SCIENTIFIC PAPERS July 1, 2005 – June 30, 2006 50 BOOKS & BOOK CHAPTERS 69 APPENDIX A - Medical and Scientific Staff as at June 30, 2006 71 APPENDIX B - Technical & Support Staff as at June 30, 2005 73 APPENDIX C - Technical & Support Staff Changes 75 APPENDIX D - Residents 76 APPENDIX E - Fellows 77 APPENDIX F - Graduate Students 2005-2006 78 APPENDIX G - Post Doctoral Students 81 APPENDIX H - Summer Students May – August 2005 82 APPENDIX I - Reportable Tests 83 APPENDIX J - External Service Linkages 85 APPENDIX K - April 2006 Departmental Rounds 86 INTRODUCTION & OVERVIEW 2005-2006 Over the past year, there have been two major changes The establishment of Laboratory Medicine and Infection related to Pathology and Laboratory Medicine, the Control as a Centre of Excellence acknowledges the establishment of Laboratory Medicine and Infection Control strengths and stature of both Pathology and Laboratory as a Mount Sinai Hospital Centre of Excellence, and the Medicine and Medical Microbiology not only at Mount Sinai establishment of MOUNT SINAI SERVICES, the commercial Hospital but in the external community. That Laboratory vehicle for Pathology and Laboratory Medicine and Medical Medicine and Infection Control is considered a Centre Microbiology. of Excellence is a major opportunity for the laboratories at Mount Sinai Hospital, as this is a virtually unique Mount Sinai Hospital is in the midst of substantial organizational structure in Canadian health care. expansion and transformational change. The Toronto Centre for Phenogenomics and the Samuel Lunenfeld For many years, Pathology & Laboratory Medicine has Research Institute expansion at 11 Orde Street are under served clients beyond Mount Sinai. These clients include construction and will soon be operational. Mount Sinai other hospitals but also pharma and medical device has also received permission and funding from the Ontario corporations in the private sector. This commercial activity government towards building a patient care obstetrics has brought many benefits including connectivity to the facility, an ambulatory surgery centre and refurbishing community and access to advanced technology from its facilities. As well, the hospital has established a new around the world to Mount Sinai Hospital. In recognition strategic plan. This new strategic plan includes five clinical of these benefits, a new company, MOUNT SINAI SERVICES, centres of excellence: Women’s and Infant’s Health, has been established to expand future commercial Chronic diseases (medicine), Surgical specialties and opportunities related to diagnostics. Oncology, the Samuel Lunenfeld Research Institute, and most notably, Laboratory Medicine and Infection Control. This year, a substantial boost to laboratory services We welcome Dr. Patrick Shannon to our staff. Dr. infrastructure at Mount Sinai Hospital was the award Shannon is a neuropathologist with a special interest in of $1,248,000 of federal/provincial Designated Medical developmental perinatology. Dr. Shannon will join Dr. Equipment funding to laboratory services. For Pathology Sarah Keating and Dr. Sandra Viero in building the regional and Laboratory Medicine this has facilitated several program in Fetal and Perinatal Pathology. important initiatives including an automated blood bank system, renewal of our coagulation system, and flow All of us were deeply saddened by the death of our cytometer, and the establishment of more automated beloved colleague, Dr. Yvan Bédard. Yvan was widely histologic processing technology. regarded as one of Canada’s most outstanding diagnostic cytopathologists and pathology educators. In his career Over the past year, our collaborative activity with the at Mount Sinai Hospital spanning 34 years, Dr. Bédard Hospital for Sick Children has increased greatly. These educated over 60 residents and fellows in cytopathology. collaborations include perinatal pathology, and genetics. A notable clinical development has been the establishment The advancement of Pathology and Laboratory Medicine of the Fred Litwin Clinical Genetics Centre which will at Mount Sinai Hospital is highly dependent on expertise amplify Mount Sinai’s strength in clinical genetics. This is of both our medical/scientific and support staff and their accompanied by further outreach of our laboratory genetics capacity to work together towards the common goals services including a collaborative program with Lakeridge of enhancing health care, education and research. We Health Centre. acknowledge their continuing contributions with gratitude and pride. Once again, we thank the administration of Mount Sinai Hospital led by Joseph Mapa for continuing support and encouragement of all our endeavours. HONOURS/AWARDS/APPOINTMENTS Appointments Dr. Yvan Bédard, Head of Cytopathology and Electron Microscopy, Pathology and Laboratory Medicine, has been selected as the 2006 recipient of the Laboratory Medicine and Pathobiology, University of Toronto, Distinguished Service Award. This award honours Dr. Bédard’s 34 years of leadership in teaching and innovative service related to Cytopathology and Electron Microscopy, as well as his local and national contributions in the advancement of resident education. Dr. Terry Colgan has been appointed Section Editor for Cytopathology, Archives of Pathology & Laboratory Medicine. Dr. Terry Colgan has been appointed Co-Chair, Toronto Regional Co-coordinating Committee, (for Laboratory Reform), Ministry of Health and Long Term Care, Province of Ontario. As well, Dr. Colgan has been appointed Academic Representative to the Laboratory Medicine Funding Implementation Committee (LMFIC) of the Ministry of Health and Long Term Care, Ontario, and the Ontario Medical Association. Dr. Terry Colgan has been appointed External reviewer, Division of Anatomical Pathology, Ottawa University. Dr. Eleftherios Diamandis has extended his clinical biochemistry administration responsibilities with his appointment as Biochemist-in-Chief at the University Health Network. Dr. Eleftherios was appointed as Associate Member, Samuel Lunenfeld Research Institute. Dr. Eleftherios Diamandis has been appointed to the Editorial Board of Clinical Proteomics. Dr. Marc Grynpas has been appointed as a scientific officer to the Canadian Institute of Health Research, Clinical Investigation Grant Panel. Dr. Marc Grynpas has been appointed a member of the Editorial Board, Calcified Tissue International. Mr. Gaman Modi has been appointed as a member of the Board of Directors to the Ontario Safety Association for Community & Healthcare for a 3 year term from 2005 to 2008. As well, Mr. Modi has been appointed as Vice Chair to the Advisory Board of the Ontario Laboratory Accreditation Program, QMP-LS, 2005-2006 and has been re-appointed to the Scientific Advisory Panel for the Canadian Journal of Medical Laboratory Science, 2005-2006. | 7 Awards Dr. Anita Bane received the Irish-North American Association of Pathologists’ award, for her platform presentation ”BRCA2 associated breast cancers exhibit a luminal phenotype despite their high histologic grade” at the United States and Canadian Academy of Pathology Meeting, Atlanta, 2006. Dr. Eleftherios Diamandis was awarded the Frey-Werle commemorative gold medal from the Frey-Werle Foundation, Australia, 2006. Dr. Valérie Dubé, Clinical Fellow, supervised by Dr. Terry Colgan received the Best Platform Presentation Award at the Annual U of T Department of Obstetrics and Gynecology Research Day in May 2006, for an oral presentation of her paper: “The Toronto Endometrial Proteomic Initiative: towards discovery of new endometrial cancer biomarkers”. Dr. Mock received a scholastic teaching award from the Alpha Omega fraternity, Toronto, 2006. Dr. Anne Marie Mulligan, Clinical Fellow, supervised by Dr. Frances O’Malley has been selected as a faculty member for the Toronto Breast Day Continuing Education Program. Dr. Kenneth Pritzker was the recipient of the Karen McGibbon Award of Excellence together with Mount Sinai Hospital Network of Knowledge Team affiliated with the Peter Silverman Centre for International Health, 2005. CLINICAL SERVICES Patient Services Patient Services is one of Mount Sinai’s front doors with over 90,000 patients seen each year by our dedicated staff. Over the year, space was secured and plans were advanced for enlarging our ambulatory care laboratory at 700 University Avenue. Clinical Biochemistry Maternal Serum Screening Program: The Program continued to grow in size and complexity with the addition of a new
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