Product Datasheet

BLCAP Conjugated Antibody

Catalog No: #C48125

Package Size: #C48125-AF350 100ul #C48125-AF405 100ul #C48125-AF488 100ul Orders: [email protected] Support: [email protected] #C48125-AF555 100ul #C48125-AF594 100ul #C48125-AF647 100ul

#C48125-AF680 100ul #C48125-AF750 100ul #C48125-Biotin 100ul

Description

Product Name BLCAP Conjugated Antibody

Host Species Mouse

Clonality Monoclonal

Species Reactivity Hu, Rt

Immunogen Description Peptide

Conjugates Biotin AF350 AF405 AF488 AF555 AF594 AF647 AF680 AF750

Other Names Bc10 antibody Bladder cancer 10 kDa protein antibody Bladder cancer related protein (10kD) antibody

Bladder cancer-associated protein antibody BLCAP antibody BLCAP_HUMAN antibody

Accession No. Swiss-Prot#:P62952

Formulation 0.01M Sodium Phosphate, 0.25M NaCl, pH 7.6, 5mg/ml Bovine Serum Albumin, 0.02% Sodium Azide

Storage Store at 4°C in dark for 6 months

Application Details

Suggested Dilution:

AF350 conjugated: most applications: 1: 50 - 1: 250

AF405 conjugated: most applications: 1: 50 - 1: 250

AF488 conjugated: most applications: 1: 50 - 1: 250

AF555 conjugated: most applications: 1: 50 - 1: 250

AF594 conjugated: most applications: 1: 50 - 1: 250

AF647 conjugated: most applications: 1: 50 - 1: 250

AF680 conjugated: most applications: 1: 50 - 1: 250

AF750 conjugated: most applications: 1: 50 - 1: 250

Biotin conjugated: working with enzyme-conjugated streptavidin, most applications: 1: 50 - 1: 1,000

Background

BLCAP is a highly conversed gene with two exons and an intron encoding a 10kDa protein, which was originally identified from invasive bladder carcinoma in 2002. BLCAP is subject to adenosine to inosine (A-to-I) RNA editing. A-to-I RNA editing is an important post-transcription modification of RNA sequence, generating a diversity of RNA products different from the original DNA sequence. The adenosine deaminase acting on double-stranded RNA (ADAR) family of enzymes catalyze the conversion of adenosine (A) to inosine (I) in the double stranded RNA, and inosine is finally recognized as guanosine (G) in the process of mRNA translation. May regulate cell proliferation and coordinate apoptosis and cell cycle progression via a novel mechanism independent of both p53/TP53 and NF-kappa-B.

Address: 8400 Baltimore Ave., Suite 302, College Park, MD 20740, USA http://www.sabbiotech.com 1 Note: This product is for in vitro research use only and is not intended for use in humans or animals.

Address: 8400 Baltimore Ave., Suite 302, College Park, MD 20740, USA http://www.sabbiotech.com 2