CURRICULUM VITAE NAME GEORGE AYODO PHD PERSONAL DATA DATE OF BIRTH NOVEMBER 12TH, 1972 PLACE OF BIRTH NATIONALITY KENYAN PROFESSION ACADEMIC STAFF P. O Box 210, DEPARTMENT OF PUBLIC HEALTH, SCHOOL OF HEALTH SCIENCES, JARAMOGI OGINGA ODINGA UNIVERSITY OF SCIENCE AND TECHNOLOGY BONDO, CONTACT ADDRESS E. MAIL: [email protected] /[email protected] CELL PHONE: +254 737 773 914 / +254 712 176 738 1. SUMMARY OF TEACHING EXPERIENCE Teaching experience over 10 years a) PhD students Completed and in progress). 1) Nyangahu Ondigo Bartholomew PG/PHD/0108/2010 Validation of a cytometric multiplex assay and antibody responses to plasmodium falciparum antigens in the highlands of western Kenya during a period of low transmission 2) Ng’ong’a Otieno Gabriel H162/4542/2014 HIV-1 Drug resistance associated mutations among injecting drug users 3) PAUL MATHEWS OTIENO (H162/4108/2018) The Effects Of Integrated Home And Hospital Based Management On The Risk And Occurrence Of Hypertension And Related Morbidities Among Patients In Resource Limited Settings 4) ERIC OMOI MAYAKA (H162/4189/2018) Service Utilization And Effective Delivery Of Screening And Treatment For Cervical Cancer In Resource Limited Settings 5) MILKA AWUOR OGAYO (H162/4190/2018) Strengthening Community Based Interventions For Malnutrition And Diarrhea Among Children Under-Five Years In Informal Settlements. 6) WILFRED OBWAYA OBWOCHA (H162/4242/2018) Strengthening Utilization Of Quality Health Information In Implementing Health Strategic Plans To Reduce Maternal Morbidity And Mortality b) Master students (Completed) 1. OGWELA CARREN ATIENO (H132/4293/2016) Factors Influencing Utilization Of Antenatal Health Care Services At Migosi Sub-County Hospital, County 2. CHRISTIAN BERNARD OCHIENG (H151/4436/2013) Modeling Socio-Economic Determinants Of Early Childhood Developmental Delays In Ugunja Sub-Location, Western Kenya 3. EMMANUEL GRIFFINS OUMA (H152/4070/2014) DETERMINANTS OF MOTHER-TO- CHILD HIV TRANSMISSION AMONG HIV EXPOSED INFANTS IN , RURAL WESTERN KENYA 4. GWER JUSTUS OGUTU H151/4212/2012 Evaluation Of The Interventions For Prevention And Control Of Diarrheal Diseases In Secondary Schools In Nyando Sub-County, , Kenya 5. COLLINS KIPKOSGEI KIRUI (H153/4488/2014) Knowledge, Practice, And Perception Of Health Care Workers Towards Diagnosis Of Childhood Tuberculosis: A Case Study Of Bureti Sub County, , Kenya 6. WILLIAM OKELLO OLAKA (H153/4154/2015) Determinants Of Health Seeking Behavior For Children Under Five Years With Malarial Fever In West Sub-County, County, Kenya

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7. Milka Awuor Ogayo (H153/4231/2014) Quality of health care services in Surgical-Orthopedic wards of Jaramogi Oginga Odinga Teaching and Referral Hospital in Kisumu county Kenya 8. Richard Nyamai (H153/4151/2015) Effect of timely treatment and effective utilization of insecticide treated nets (ITNs) on hospitalization of children under five years 9. Erick Omoi Mayaka H152/4243/2014 Cervical cancer screening uptake among women at Koginga fish landing site in county, Kenya 10. Wilfred Obwaya Obwocha H152/4062/2013 Utilization of healthcare information among healthcare workers in Gucha sub-county, , Kenya 11. Brian Kedode Mwangi H153/4376/2014 Factors associated with default from tuberculosis treatment in 12. Jeremiah Oloo Okatch (H152/4094/13) Evaluation of the impact of health sector services fund on the quality of maternity services at the health centres in Kisii south sub-county, Kisii county, Kenya. 13. Godner Bwari Peter Determinants of cervical cancer screening practice among women of reproductive age in Nyaribari Chache sub-county 14. Elizabeth Achieng Kagombe H152/4227/2012 Impact of undernutrition on response to malaria treatments among children under five years in Ahero Sub-county hospital and Homabay county Hospital 15. Webala Akinyi Brenda i56/24062/2013 Prevalence of fetal hemoglobin and antibody responses to Plasmodium falciparum antigens in sickle cell disease patients in western Kenya 16. Michael Kisongochi Walukhu i56/10017/07antibody responses to Plasmodium falciparum circumsporozoite protein and schizont extract in idividuals living at Kipsamoite, , Kenya. 17. Onyango Elizabeth Opiyo (PG/MPH/013/09) Adherence to Artemisinin-Based Combination Therapy (ACT) for treatment of uncomplicated malaria in Southeast Alego, Karemo Division,Siaya District, Kenya c) External Examiner a) Maseno University, School of Biological Sciences /Public Health (Masters and PhD) b) Kenyatta University School of Medicine / Public Health (Masters and PhD) 2. EDUCATION Year (from – to) Degree, Institution 2009 – 2013 Post Doc (University of Minnesota / KEMRI)- Applied Epidemiology 2004-2009 PhD (Kenyatta University - Kenya / Harvard Medical School - USA)- Population Genetics 1995-1997 MSc (Guru Nanak Development University, India) – Human Genetics 1992-1995 BSc (Mohanlal Sukhadia University, India) – Zoology, Chemistry and Botany 3. CURRENT EMPLOYMENT AND POSITIONS PREVIOUSLY HELD Years since Company / Institution 2015 -To Date Senior Lecturer, Depatrment of Public Health, Jaramogi Oginga Odinga University of Science and Technology 2015-Todate Coordinator of Postgraduate program at School of Health Sciences in JOOUST 2009-2015 Consultant KEMRI / IndIana University Research Projects 2002-2003 Program Director, Indiana University and KEMRI research projects

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Forensic Analyst at Government Chemist Department, Kenya

4. AWARDS Year (from – to) Position, Project / Programme, Company / Institution / Client Description of roles and responsibilities 2017-2018 African leadership fellow, Cape Town University

2014-2015 Research fellow, Northern Pacific Global Health Research Fellows training consortium 2005-2007 Graduate Student fellowship at Harvard Medical School 5. TEACHING/COURSE COMPETENCY School/Institute Class/Discipline 2007-2009 Cell Biology, Biochemistry and General Genetics, School of Medical Sciences, Kenyatta University 2010-2014 Basic biostatistics and biometric, and medical instrumentation (Undergraduate level). Microbial Genetics and Research Methods (Postgraduate level) 2015 – to-date Research Methods, Epidemiologic methods, Microbial Genetics, Bioethics, Communicable and Non-Communicable Diseases (Postgraduate level) Research Methods, critical thinking and academic writing, Basic Bio-statistics, Demograhy and Health (Undergraduate level) 6. OUTREACH ACTIVITIES Year Position/Programme/Institution 2015 -to-date Chairman, Board of management of Rarieda Secondary School, Siaya County 2015 –2018 Vice Chairman, Board of management of Mahaya Secondary School, Siaya County 7. CURRENT RESEARCH AND COLLABORATIONS (Past and Present) Years/Duration Position /Title / Sponsor 2018-2022 An investigator: Malaria transmission and immunology (MTI): Identifying risk factor for continued low malaria transmission in the highlands of western Kenya

2019-2022 An investigator: Adaptation of NIH toolbox pediatric cognitive tests for use in a pilot study to assess cognitive outcomes in asymptomatic malaria infections in western Kenya

2017-2020 An investigator: Archaeological and Genetic Approaches to Ancient East African Population Structure sponsored by Harvard University.

2017-2019 Co-PI: Understanding experiences of menstruation, fertility awareness, and perceptions of preterm birth among women and men in Western Kenya sponsored by Bill Gates and University of California. 2015-2018 Co-PI; Determining the prevalence and density of asymptomatic plasmodium

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falciparum infections in low and high transmission settings in Western Kenya: a pilot study to select appropriate sites for a mosquito infectivity study sponsored by Indiana University 2014-2015 PI: Interaction of iron deficiency and clinical malaria and other infections sponsored by Fogarty Fellowship Grant 2011- 2013 Co-PI: How does transmission of malaria transmission affect immune responses to P. falciparum and anemia? Sponsored by University of Minnesota, USA 2013-2016 Co-PI: Fetal 4aemoglobin expression; Decephering its role in malaria protection and also exploring it to identify Bio-markers for sickle cell disease. Sponsored by University of Montreal, Canada 2012-2016 Co-PI: The effect of HIV infection on malaria specific T and B cell responses in Western Kenya, Sponsored by NIH, USA 2014 2016 Co-PI; Development of termite harvester, NACOSTI, Kenya. 8. CONSULTANCIES / REVIEWER Year Position, Project / Programme, Company / Institution / Client from – to Description of roles and responsibilities 2015-Todate Reviewer KEMRI ethics committee, CGHR-Kisumu 2015 - Todate Consultant, Development of curriculum for Autistic children for Center for global health and child Development Kenya. 2015- Todate Reviewer for WACCBIP-DELTAS Postdoctoral Fellowships 2015- Todate Reviewer for the NACOSTI / NATIONAL RESEARCH FUND grant applications 2014- Todate Reviewer for African Society for Lab Medicine (ASLM)

9. TRAININGS /WORKSHOPS/SYMPOSIA ATTENDED 2018/9 only Nobv 2019 ASTMH Conference, Washington USA Nov 2019 Workshop to prepare malaria strategic plan 2019-2023, Kenya July, 2018 Pretem birth conference, Nairobi, Kenya 10. LANGUAGE PROFICIENCY (English, Kiswahili and Dholuo)

11. PUBLICATIONS

1. Karen E.S. Hamre, James S. Hodges, George Ayodo, Chandy C. John.“Spatial malaria incidence and intervention coverage before and after a 13-month period of possible interruption of clinical malaria in highland Kenya”. Accepted for publication AJTMH, 2020 2. Ondigo, BN., Hamre, KES., Frosch, AEP., Ayodo G., White, MT. and John, CC., “Antibody profiles to P. falciparum antigens over time characterize acute and long-term malaria exposure in an area of low and unstable transmission. Accepted for publication AJTMH, 2020 3. Karen E.S. Hamre, Bartholomew N. Ondigo, James S. Hodges, Sheetij Dutta, Michael Theisen, George Ayodo, Chandy C. John Antibody correlates of protection from clinical Plasmodium falciparum malaria in an area of low and unstable malaria transmission Accepted AJTMH 2020. 4. Karen E.S. Hamre, George Ayodo, James S. Hodges3, Chandy C. John A mass insecticide-treated bed net distribution campaign reduced malaria risk on an individual but not population level in a highland epidemic-prone area of Kenya Accepted AJTMH, 2020 5. Nadia Diamond-Smith, George O. Onyango, Salome Wawire, GeorgeAyodo. Knowledge of menstruation and fertility among adults in rural Western Kenya: Gaps and opportunities for

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support PLoS One. 2020; 15(3): e0229871. 6. Eliud O. Odhiambo, Dibyadyuti Datta, Bernard Guyah, George Ayodo, Bartholomew N. Ondigo, Benard O. Abong’o, Chandy C. John, Anne E. P. Frosch HIV infection drives IgM and IgG3 subclass bias in Plasmodium falciparum-specific and total immunoglobulin concentration in Western Kenya Malar J. 2019; 18: 297. 7. Ogwela C. Atieno, Ochanda Damaris and Ayodo George Provision of antenatal care services and level of utilization at Migosi sub-county Hospital, Western Kenya. Accepted IJDR. 8. Prendergast ME, Lipson M, Sawchuk EA, …..Ayodo G, ----Reich D.AncientDNA reveals a multistep spread of the first herders into sub-Saharan Africa. Science. 2019 Jul 5;365(6448). 9. Frosch AEP, Ayodo G, Odhiambo EO, Ireland K, Vulule J, Cusick SE. Iron Deficiency is Prevalent among HIV-Infected Kenyan Adults and is Better Measured by Soluble Transferrin Receptor than Ferritin. Am J Trop Med Hyg. 2018 Aug;99(2):439-444. 10. Ogol Japheth, Ochanda Damaris Ayodo George Hospitalization Events Among Sickle Cell Anemia Patients at Homabay County Referral Hospital, Western Kenya. Journal of Health, Medicine and Nursing Vol 52, 2018: 11. Milka A. Ogayo, George Ayodo, Fred Amimo. Hand Hygiene Practice by Healthcare Workers at Surgical Orthopedic Wards of Jaramogi Oginga Odinga Teaching and Referral Hospital, Kenya East Africa Medical Journal Accepted 2017. 12. Utilization of healthcare information among healthcare workers in Gucha Sub-County, Kisii County, Kenya W.O. OBWOCHA, G. AYODO and A. NYAGUARA. East African Medical Journal Vol. 91 No. 1 January 2017 13. .Kagombe EObonyo C Ayodo G Were V. Prevalence of Under Nutrition and Its Effects on Response to Malaria Treatments Among Children Under Five Years at Ahero and Homa Bay Hospitals, Western Kenya. Journal of Health Medicine and Nursing Vol 28, 2016 14. Christian Ochieng, Damaris Ochanda, Fred Amimo, Teresa Njoki, Justus Ikemeri, George Ayodo. Evaluating parental screening tool for developmental milestone in children under five years in rural western Kenya. IJSRP Volume 7, Issue 7, July 2017 Edition 15. Frosch AE, Odumade OA, Taylor JJ, Ireland K, Ayodo G, Ondigo B, Narum DL,Vulule J, John CC. Decrease in Numbers of Naive and Resting B Cells in HIV-Infected Kenyan Adults Leads to a Proportional Increase in Total and Plasmodium falciparum-Specific Atypical Memory B Cells. J Immunol. 2017 Jun 15;198(12):4629-4638. 16. Interferon-γ responses to Plasmodium falciparum vaccine candidate antigens decrease in the absence of malaria transmission. Ayieko C, Ogola BS, Ochola L, Ngwena GA, Ayodo G, Hodges JS, Noland GS, JohnCC. Peer J. 2017 Jan 10;5:e2855. 17. The Simons Genome Diversity Project: 300 genomes from 142 diverse populations. Mallick S, Li H, Lipson M, Mathieson I, Gymrek M, Ayodo G, Comas D, Hammer Patterson N, Reich D. Nature. 2016 Oct 13;538(7624): 18. Successful Global Health Research Partnerships:What Makes Them Work? John CC, Ayodo G, Musoke P. Am J Trop Med Hyg. 2016 Jan;94(1):5-7. doi: 10.4269/ajtmh.15-0611. Epub 2015 Oct 19. 19. Sudmant PH, Mallick S, Nelson BJ, ---Ayodo G, ----Reich D, Eichler EE. Global diversity,population stratification, and selection of human copy number variation. Science. 2015 Aug 6. pii: aab3761. 20. Lazaridis L, ……..Ayodo G---Reich D, Krause J et al, Ancient human genome suggest 3 ancestral population for present-day Europeans. Nature 2014 Sept 513: 409- 13 21. Frosch AE, Ondigo BN, Ayodo G, Vulule JM, John CC, Cusick SE. Decline in childhood iron deficiency after interruption of malaria transmission in highland Kenya. Am J Clin Nutr. 2014 Jul 30. pii: ajcn.087114. 22. Mutanda AL, Cheruiyot P, Hodges JS, Ayodo G, Odero W, John CC. Sensitivity of fever for

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diagnosis of clinical malaria in a Kenyan area of unstable, low malaria transmission. Malar J. 2014 Apr 30;13:163. doi: 10.1186/1475-2875-13-163. 23. .Thomson R, Genovese G, Canon C, Kovacsics D, Higgins MK, Carrington M, Winkler CA, Kopp J, Rotimi C, Adeyemo A, Doumatey A, Ayodo G, Alper SL, Pollak MR, Friedman DJ, Raper J. Evolution of the primate trypanolytic factor APOL1. Proc Natl Acad Sci U S A. 2014 May 20;111(20):E2130-9. doi: 24. Kawaka, F., Kimenju, J., Okoth, S. A., Ayodo, G., Mwaniki, S., Muoma, J., & Orinda, G. Effects of Soil Chemical Characteristics on the Occurrence of Entomopathogenic Nematodes. British Journal of Applied Science & Technology, 2014 June; 4(16), 2333-2343. 25. .Ochola LA, Ng'wena GM, Noland GS, Ondigo BN, Ayodo G, John CC. The Plasmodium falciparum Antigen MB2 Induces Interferon-γ and Interleukin-10 Responses inAdults in Malaria Endemic Areas of Western Kenya. J Glob Infect Dis. 2013 Oct;5(4):131-7. doi: 10.4103/0974-777X.122001. 26. Ayieko C, Maue AC, Jura WG, Noland GS, Ayodo G, Rochford R, John CC . Changes in B Cell Populations and Merozoite Surface Protein-1-Specific Memory B Cell Responses after Prolonged Absence of Detectable P. falciparum. PLoS One. 2013 Jun 27;8(6):e67230 27. Ondigo BN, Park GS, Gose SO, Ho BM, Ochola LA, Ayodo GO, Ofulla AV, John CC. Standardization and validation of a cytometric bead assay to assess antibodies to multiple Plasmodium falciparum recombinant antigens. Malar J. 2012 Dec 21;11:427. 28. Onyango EO, Ayodo G, Watsierah CA, Were T, Okumu W, Anyona SB, Raballah E, Okoth JM, Gumo S, Orinda GO, Ouma C. Factors associated with non-adherence to Artemisinin-based Combination Therapy (ACT) to malaria in a rural population from holoendemic region of western Kenya. BMC Infect Dis. 2012 Jun 24;12(1):143. 29. Noland GS, Ayodo G, Abuya J, Hodges JS, Rolfes MA, John CC. Decreased prevalence of anemia in highland areas of low malaria transmission after a 1-year interruption of transmission. Clin Infect Dis. 2012 Jan;54(2):178-84. 30. McCarra MB, Ayodo G, Sumba PO, Kazura JW, Moormann AM, Narum DL, John CC. Antibodies to Plasmodium falciparum erythrocyte-binding antigen-175 are associated with protection from clinical malaria. Pediatr Infect Dis J. 2011 31. Fanuel Kawaka, John W. Kimenju, George Ayodo, Shelmith W. Mwaniki, John O. Muoma, Sheila A. Okoth and George O. Orinda. Impact Of Land Use On The Distribution And Diversity Of Entomopathogenic Nematodes In Embu And Taita Districts, Kenya. Tropical and Subtrop Agroecosystems 13 (2011) 59-63 32. Le TM, Willis AS, Barr FE, Cunningham GR, Canter JA, Owens SE, Apple RK, Ayodo G, Reich D, Summar ML. An ethnic-specific polymorphism in the catalytic subunit of glutamate-cysteine ligase impairs the production of glutathione intermediates in vitro. Mol Genet Metab. 2010 Sep;101(1):55-61 33. Ayodo G, Price AL, Keinan A, Ajwang A, Otieno MF, Orago AS, Patterson N, Reich D. Combining evidence of natural selection with association analysis increases power to detect malaria-resistance variants. Am J Hum Genet. 2007 Aug; 81(2):234-42.

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12. REFEERES: 1. Prof Chandy John Professor of Pediatrics and Medicine Indiana University, USA Tel + 1 612 625 8383 Email: [email protected] 2. Prof Fred Amimo PhD Dean, School of Health Sciences Tel: +254 720 332486; Email address: [email protected] 3. Prof David Reich PhD Professor, Department of Genetics, Harvard Medical School, Boston, USA. Tel: +1 617 432 1101; Email address: [email protected]

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