WO 2010/142752 Al
(12) INTERNATIONAL APPLICATION PUBLISHED UNDER THE PATENT COOPERATION TREATY (PCT) (19) World Intellectual Property Organization International Bureau (10) International Publication Number (43) International Publication Date 16 December 2010 (16.12.2010) WO 2010/142752 Al (51) International Patent Classification: nia 94568 (US). ROBARGE, Kirk D. [US/US]; 1679 C07D 213/75 (2006.01) Λ61K 31/4439 (2006.01) 27th Avenue, San Francisco, California 94122 (US). C07D 401/12 (2006.01) A61K 31/444 (2006.01) STANLEY, Mark S. [US/US]; 284 Lauren Avenue, A61K 31/506 (2006.01) A61P 37/04 (2006.01) Pacifica, California 94044 (US). TSUI, Vickie Hsiao- A61K 31/495 (2006.01) Wei [US/US]; 2626 Martinez Avenue, Burlingame, Cali fornia 94010 (US). WILLIAMS, Karen [GB/GB]; 8/9 (21) International Application Number: Spire Green Centre, Flex Meadow, Harlow, Essex CM 19 PCT/EP2010/058128 5TR (GB). ZHANG, Birong [US/US]; 3060 San Andreas (22) International Filing Date: Drive, Union City, California 94587 (US). ZHOU, Aihe 10 June 2010 (10.06.2010) [US/US]; 1361 Stephen Way, San Jose, California 95129 (US). (25) Filing Language: English (74) Agent: KLOSTERMEYER-RAUBER, Doerte; Gren- (26) Publication Language: English zacherstrasse 124, CH-4070 Basel (CH). (30) Priority Data: (81) Designated States (unless otherwise indicated, for every 61/186,322 11 June 2009 ( 11.06.2009) US kind of national protection available): AE, AG, AL, AM, (71) Applicant (for all designated States except US): F. AO, AT, AU, AZ, BA, BB, BG, BH, BR, BW, BY, BZ, HOFFMANN-LA ROCHE AG [CWCH]; Grenzacher- CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, strasse 124, CH-4070 Basel (CH).
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