Etho Climate Leadership U.S
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Prostate Cancer in Focus
PROSTATE CANCER IN FOCUS Current Developments in the Management of Prostate Cancer Section Editor: Andrew J. Armstrong, MD Prostate Cancer Prostate PSMA-Targeted Therapy in Prostate Cancer Scott T. Tagawa, MD, MS Professor of Medicine and Urology Weill Cornell Medicine New York, New York H&O What is prostate-specific membrane agent such as a monoclonal antibody might be able to antigen (PSMA), and what makes it a good target target a tumor without binding to other PSMA-positive for the treatment of prostate cancer? sites owing to its large size and physical inability to reach luminal sites of expression that are separated from the ST PSMA is a cell surface antigen that is expressed to vasculature by tight junctions. a limited degree on certain normal cells in the body but generally is highly overexpressed in the setting of prostate H&O How is PSMA positivity established? cancer. Normal cells that express PSMA are located in the prostate, salivary, and lacrimal glands; the proximal part ST Imaging and biopsy are the main ways to establish of the small intestine; the proximal renal tubules; and PSMA positivity. Multiple imaging modalities are avail- some ganglia. In the setting of prostate cancer, PSMA able worldwide. The agent indium In 111 capromab expression generally increases along with the cancer grade, pendetide (ProstaScint) has been approved for years in and it also increases following hormonal therapy. In addi- the United States, and the US Food and Drug Adminis- tion, PSMA expression tends to be higher in metastatic tration (FDA) approved the use of gallium Ga 68 PSMA- sites than in primary tumors. -
View Annual Report
Five trillion dollars of securities trade on NasdaqT. Where will the five trillion dollars of commercial real estate assets trade? Annual Report 1999 www.costargroup.com mission statement Through its products and services, CoStar Group, Inc. offers customers access to the most comprehensive, verified database of real estate infor- mation on the U.S. commercial real estate industry. Today, CoStar is creating the Internet marketplace for commercial real estate by bringing together its extensive database, 700 experienced researchers, technological expertise and a broad customer base comprised of the most active real estate firms trans- acting business in the United States. CoStar’s goal is to improve liquidity and ultimately increase the value of commercial real estate. table of contents Financial Highlights.................Page 1 Letter to Our Shareholders.....Page 2 1999 Form 10K.........................Page 5 financial highlights in thousands except per share data 1997 1998 1999 Revenues . $ 7,900 $13,900 $ 30,234 Net loss . (3,266) (3,185) (12,277) Net loss per share . (0.57) (0.44) (1.05) Weighted average common shares . 5,722 7,213 11,727 Cash and cash equivalents . 1,069 19,667 94,074 Total assets . 6,581 27,541 136,905 Stockholders’ equity . 2,917 23,203 119,697 growth in revenue database markets growth ($ millions) growth (billions of sq. ft.) 50 $35 20 30 40 15 25 30 20 10 15 20 10 5 10 5 0 0 0 ’97 ’98 ’99 ’97 ’98 ’99 ’97 ’98 ’99 1 to our shareholders improved liquidity, resulting in increased valuations for their assets. Just as the Nasdaq, in 1971, provided over-the-counter securities brokers a centralized, digital marketplace, facilitating over 500% growth and escalating market value to $5 trillion today—we believe CoStar is positioned to be the exchange that realizes significant value for the $5 trillion commercial real estate asset class. -
Wilmington Funds Holdings Template DRAFT
Wilmington Global Alpha Equities Fund as of 5/31/2021 (Portfolio composition is subject to change) ISSUER NAME % OF ASSETS USD/CAD FWD 20210616 00050 3.16% DREYFUS GOVT CASH MGMT-I 2.91% MORGAN STANLEY FUTURE USD SECURED - TOTAL EQUITY 2.81% USD/EUR FWD 20210616 00050 1.69% MICROSOFT CORP 1.62% USD/GBP FWD 20210616 49 1.40% USD/JPY FWD 20210616 00050 1.34% APPLE INC 1.25% AMAZON.COM INC 1.20% ALPHABET INC 1.03% CANADIAN NATIONAL RAILWAY CO 0.99% AIA GROUP LTD 0.98% NOVARTIS AG 0.98% TENCENT HOLDINGS LTD 0.91% INTACT FINANCIAL CORP 0.91% CHARLES SCHWAB CORP/THE 0.91% FACEBOOK INC 0.84% FORTIVE CORP 0.81% BRENNTAG SE 0.77% COPART INC 0.75% CONSTELLATION SOFTWARE INC/CANADA 0.70% UNITEDHEALTH GROUP INC 0.70% AXA SA 0.63% FIDELITY NATIONAL INFORMATION SERVICES INC 0.63% BERKSHIRE HATHAWAY INC 0.62% PFIZER INC 0.62% TOTAL SE 0.61% MEDICAL PROPERTIES TRUST INC 0.61% VINCI SA 0.60% COMPASS GROUP PLC 0.60% KDDI CORP 0.60% BAE SYSTEMS PLC 0.57% MOTOROLA SOLUTIONS INC 0.57% NATIONAL GRID PLC 0.56% PUBLIC STORAGE 0.56% NVR INC 0.53% AMERICAN TOWER CORP 0.53% MEDTRONIC PLC 0.51% PROGRESSIVE CORP/THE 0.50% DANAHER CORP 0.50% MARKEL CORP 0.49% JOHNSON & JOHNSON 0.48% BUREAU VERITAS SA 0.48% NESTLE SA 0.47% MARSH & MCLENNAN COS INC 0.46% ALIBABA GROUP HOLDING LTD 0.45% LOCKHEED MARTIN CORP 0.45% ALPHABET INC 0.44% MERCK & CO INC 0.43% CINTAS CORP 0.42% EXPEDITORS INTERNATIONAL OF WASHINGTON INC 0.41% MCDONALD'S CORP 0.41% RIO TINTO PLC 0.41% IDEX CORP 0.40% DIAGEO PLC 0.40% LENNOX INTERNATIONAL INC 0.40% PNC FINANCIAL SERVICES GROUP INC/THE 0.40% ACCENTURE -
2019 Real Estate Technology Market Update
PRELIMINARY CONFIDENTIAL DRAFT Real Estate Technology Market Update Q2 2019 EXECUTIVE SUMMARY – Q2 2019 REAL ESTATE TECHNOLOGY Real estate technology continues to be one of the most active areas of financing and M&A activity through the first half of 2019 ▪ The U.S. real estate tech sector received ~$3.0Bn of growth equity capital in 1H 2019 in addition to more than $1.4Bn in debt for iBuyer and RE financing companies ▪ Investments continue to grow in size, with average equity financings over $21MM across 65 deals in Q2 2019, as competition for high-quality investments increases and the number of active strategics and private equity investors in the space continues to grow Q2 2019 saw commercial real estate technology companies drive significant activity, with a flurry of capital raises and M&A transactions ▪ VTS raised $90M at a ~$1.0Bn valuation led by Brookfield Ventures, the venture arm of Brookfield Asset Management, signaling strong demand from real estate investors / property managers for next-generation solutions to streamline their operations and improve margins ▪ A sharp increase in private equity and strategic driven M&A reflects the growing influence of CRE tech companies and the land grab that’s currently underway as acquirers look to build platforms in the space – Silver Lake and Battery Ventures backed LightBox announced two acquisitions in Q2 2019, Real Capital Markets and Digital Map Products, as they look to build an end-to-end software and data platform in the CRE space targeting commercial services firms, property -
New Opportunties - TF
New Opportunties - TF Schedule of Investments as of 2017-09-30 (Unaudited) Holding Shares/Principal Amount Market Value ($) Cotiviti Holdings Inc 82,434 2,965,975 LogMeIn Inc 26,688 2,937,014 CDW Corp/DE 44,273 2,922,018 Tivity Health Inc 65,176 2,659,181 XPO Logistics Inc 38,536 2,611,970 Burlington Stores Inc 26,646 2,543,627 Ball Corp 58,574 2,419,106 RingCentral Inc 57,626 2,405,886 Bright Horizons Family Solutions Inc 27,768 2,393,879 MSCI Inc 20,395 2,384,176 Catalent Inc 58,551 2,337,356 CyrusOne Inc 39,336 2,318,070 Dolby Laboratories Inc 38,884 2,236,608 Granite Construction Inc 38,149 2,210,735 SiteOne Landscape Supply Inc 37,779 2,194,960 CBOE Holdings Inc 20,195 2,173,588 2U Inc 38,578 2,161,911 LKQ Corp 59,115 2,127,549 Summit Materials Inc 66,267 2,122,532 AAR Corp 56,143 2,121,083 Planet Fitness Inc 78,462 2,116,905 Callidus Software Inc 83,778 2,065,128 Mercury Systems Inc 39,658 2,057,457 Pool Corp 18,587 2,010,556 Fortune Brands Home & Security Inc 29,197 1,962,914 Brunswick Corp/DE 34,991 1,958,446 Brink's Co/The 23,134 1,949,040 Cooper Cos Inc/The 8,214 1,947,622 Chegg Inc 131,125 1,945,895 Tyler Technologies Inc 11,070 1,929,722 KLX Inc 36,290 1,920,830 Paycom Software Inc 25,177 1,887,268 WABCO Holdings Inc 12,660 1,873,680 Advanced Disposal Services Inc 72,336 1,822,144 Essent Group Ltd 44,825 1,815,412 Installed Building Products Inc 28,011 1,815,113 John Bean Technologies Corp 17,938 1,813,532 Alarm.com Holdings Inc 39,789 1,797,667 ITT Inc 40,325 1,785,188 Acadia Healthcare Co Inc 37,106 1,772,183 Broadridge -
March 31, 2021
Units Cost Market Value US Equity Index Fund US Equities 95.82% Domestic Common Stocks 10X GENOMICS INC 126 10,868 24,673 1LIFE HEALTHCARE INC 145 6,151 4,794 2U INC 101 5,298 4,209 3D SYSTEMS CORP 230 5,461 9,193 3M CO 1,076 182,991 213,726 8X8 INC 156 2,204 4,331 A O SMITH CORP 401 17,703 28,896 A10 NETWORKS INC 58 350 653 AAON INC 82 3,107 5,132 AARON'S CO INC/THE 43 636 1,376 ABBOTT LABORATORIES 3,285 156,764 380,830 ABBVIE INC 3,463 250,453 390,072 ABERCROMBIE & FITCH CO 88 2,520 4,086 ABIOMED INC 81 6,829 25,281 ABM INDUSTRIES INC 90 2,579 3,992 ACACIA RESEARCH CORP 105 1,779 710 ACADIA HEALTHCARE CO INC 158 8,583 9,915 ACADIA PHARMACEUTICALS INC 194 6,132 4,732 ACADIA REALTY TRUST 47 1,418 1,032 ACCELERATE DIAGNOSTICS INC 80 1,788 645 ACCELERON PHARMA INC 70 2,571 8,784 ACCO BRANDS CORP 187 1,685 1,614 ACCURAY INC 64 483 289 ACI WORLDWIDE INC 166 3,338 6,165 ACTIVISION BLIZZARD INC 1,394 52,457 133,043 ACUITY BRANDS INC 77 13,124 14,401 ACUSHNET HOLDINGS CORP 130 2,487 6,422 ADAPTHEALTH CORP 394 14,628 10,800 ADAPTIVE BIOTECHNOLOGIES CORP 245 11,342 10,011 ADOBE INC 891 82,407 521,805 ADT INC 117 716 1,262 ADTALEM GLOBAL EDUCATION INC 99 4,475 3,528 ADTRAN INC 102 2,202 2,106 ADVANCE AUTO PARTS INC 36 6,442 7,385 ADVANCED DRAINAGE SYSTEMS INC 116 3,153 13,522 ADVANCED ENERGY INDUSTRIES INC 64 1,704 7,213 ADVANCED MICRO DEVICES INC 2,228 43,435 209,276 ADVERUM BIOTECHNOLOGIES INC 439 8,321 1,537 AECOM 283 12,113 17,920 AERIE PHARMACEUTICALS INC 78 2,709 1,249 AERSALE CORP 2,551 30,599 31,785 AES CORP/THE 1,294 17,534 33,735 AFFILIATED -
You Are Cordially Invited to Participate in the 2020 Annual Meeting Of
April 24, 2020 Dear Stockholder: You are cordially invited to participate in the 2020 Annual Meeting of Stockholders of CoStar Group, Inc., to be held at 10:00 a.m., Eastern Daylight Time, on Wednesday, June 3, 2020 (the “Annual Meeting”). We have adopted a virtual format for the Annual Meeting this year following guidance from global and U.S. health authorities to help limit the spread of the novel coronavirus, or COVID-19. The virtual Annual Meeting will consist of a live webcast. Stockholders can participate from any geographic location with Internet connectivity. You may listen, vote and submit questions during the Annual Meeting via the Internet at www.virtualshareholdermeeting.com/CSGP2020. More information regarding how you can participate in the virtual Annual Meeting is provided in the Proxy Statement. A webcast replay of the Annual Meeting’s audio will be available on the investor relations page of our website after the Annual Meeting. At the Annual Meeting, you will be asked to (1) elect the eight directors named in the Proxy Statement, (2) ratify the appointment of Ernst & Young LLP as our independent registered public accounting firm for 2020, and (3) approve, on an advisory basis, CoStar Group, Inc.’s executive compensation. The accompanying Notice of 2020 Annual Meeting of Stockholders and Proxy Statement describe these matters in more detail. The Board of Directors recommends that you vote in favor of each of the director nominees and the other proposals. Important Notice Regarding the Availability of Proxy Materials for the 2020 Annual Meeting of Stockholders To Be Held on June 3, 2020: The Proxy Statement and our 2019 Annual Report are available at http://investors.costargroup.com/financials. -
Refreshing the Biologic Pipeline 2020
news feature Credit: Science Lab / Alamy Stock Photo Refreshing the biologic pipeline 2020 In the absence of face-to-face meetings, FDA and industry implemented regulatory workarounds to maintain drug and biologics approvals. These could be here to stay. John Hodgson OVID-19 might have been expected since 1996) — a small miracle in itself “COVID-19 confronted us with the need to severely impair drug approvals (Fig. 1 and Table 1). to better triage sponsors’ questions,” says Cin 2020. In the event, however, To the usual crop of rare disease and Peter Marks, the director of the Center for industry and regulators delivered a small genetic-niche cancer treatments, 2020 Biologics Evaluation and Research (CBER) miracle. They found workarounds and also added a chimeric antigen receptor at the FDA. “That was perhaps the single surrogate methods of engagement. Starting (CAR)-T cell therapy with a cleaner biggest takeaway from the pandemic related in January 2020, when the outbreak veered manufacturing process and the first to product applications.” Marks says that it westward, the number of face-to face approved blockbuster indication for a became very apparent with some COVID- meetings declined rapidly; by March, small-interfering RNA (siRNA) — the 19-related files that resolving a single they were replaced by Webex and Teams. European Medicines Agency’s (EMA) issue can help a sponsor enormously and (Secure Zoom meeting are to be added registration of the RNA interference accelerate the development cycle. Before this year.) And remarkably, by 31 December, (RNAi) therapy Leqvio (inclisiran) for COVID-19, it was conceivable that a small the US Food and Drug Administration cardiovascular disease. -
Altegris /AACA Opportunistic Real Estate Fund
Altegris /AACA Opportunistic Real Estate Fund PORTFOLIO OF INVESTMENTS (Unaudited) September 30, 2020 Shares Value COMMON STOCK - 36.1 % ASSET MANAGEMENT - 0.4 % 32,801 Brookfield Infrastructure Corp. $ 1,816,854 ELECTRIC UTILITIES - 0.9 % 77,975 Brookfield Renewable Corporation 4,569,320 LEISURE TIME - 12.5 % 484,238 Caesars Entertainment, Inc. * 27,146,382 3,344,000 Drive Shack, Inc. * 3,745,280 98,756 Las Vegas Sands Corp. 4,607,955 1,054,511 MGM Resorts International 22,935,614 60,393 Wynn Resorts Ltd. 4,336,821 62,772,052 REAL ESTATE - 3.0 % 890,864 IQHQ *^(a)(b) 14,887,852 TECHNOLOGY SERVICES - 5.1 % 30,069 CoStar Group, Inc. * 25,513,847 TELECOMMUNICATIONS - 14.2 % 449,324 GDS Holdings Ltd. - ADR *+ 36,768,183 2,215,783 Switch, Inc. 34,588,373 71,356,556 TOTAL COMMON STOCK (Cost - $144,134,832) 180,916,481 PARTNERSHIP SHARES -13.9 % ELECTRIC UTILITIES - 5.7 % 250,509 Brookfield Infrastructure Partners LP 11,929,239 311,899 Brookfield Renewable Partners LP 16,390,292 28,319,531 SPECIALTY FINANCE - 8.2 % 2,399,241 Fortress Transportation & Infrastructure Investors LLC 41,098,998 TOTAL PARTNERSHIP SHARES (Cost - $47,859,371) 69,418,529 REITS - 62.6 % REITS - 62.1 % 181,610 Alexandria Real Estate Equities, Inc. + 29,057,600 144,893 American Tower Corp. + 35,024,985 240,140 Americold Realty Trust 8,585,005 217,330 Crown Castle International Corp. + 36,185,445 232,737 CyrusOne, Inc. 16,298,572 25,447 Equinix, Inc. 19,343,028 234,215 Equity Lifestyle Properties, Inc. -
FORM 10-K Costar Group, Inc
UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, DC 20549 FORM 10-K ☒ ANNUAL REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the fiscal year ended December 31, 2020 OR TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE ☐ SECURITIES EXCHANGE ACT OF 1934 For the transition period from ______ to ______ Commission file number 0-24531 CoStar Group, Inc. (Exact name of registrant as specified in its charter) Delaware 52-2091509 (State or other jurisdiction of incorporation or organization) (I.R.S. Employer Identification No.) 1331 L Street, NW Washington, DC 20005 (Address of principal executive offices) (zip code) (202) 346-6500 (Registrant’s telephone number, including area code) Securities registered pursuant to Section 12(b) of the Act: Title of each class Trading Symbol Name of each exchange on which registered Common Stock ($0.01 par value) CSGP Nasdaq Global Select Market Securities registered pursuant to section 12(g) of the Act: None Indicate by check mark if the registrant is a well-known seasoned issuer, as defined in Rule 405 of the Securities Act. Yes x No o Indicate by check mark if the registrant is not required to file reports pursuant to Section 13 or Section 15(d) of the Act. Yes o No x Indicate by check mark whether the registrant (1) has filed all reports required to be filed by Section 13 or 15(d) of the Securities Exchange Act of 1934 during the preceding 12 months (or for such shorter period that the registrant was required to file such reports) and (2) has been subject to such filing requirements for the past 90 days. -
VIRTUS ZEVENBERGEN INNOVATIVE GROWTH STOCK FUND SCHEDULE of INVESTMENTS (Unaudited) MARCH 31, 2021
VIRTUS ZEVENBERGEN INNOVATIVE GROWTH STOCK FUND SCHEDULE OF INVESTMENTS (Unaudited) MARCH 31, 2021 ($ reported in thousands) Shares Value Shares Value Footnote Legend: (1) Non-income producing. COMMON STOCKS—99.0% Industrials—3.9% Communication Services—9.3% Desktop Metal, Inc. (1) Country Weightings† Coursera, Inc.(1) 7,100 $ 320 Class A 359,800 $ 5,361 (1) Uber Technologies, United States 87% Netflix, Inc. 84,500 44,080 (1) Snap, Inc. Class A(1) 586,650 30,676 Inc. 897,900 48,944 Canada 7 Zillow Group, Inc. 54,305 Brazil 5 Class C(1) 434,335 56,307 Israel 1 Information Technology—43.9% Total 100% 131,383 (1) Coupa Software, Inc. 78,450 19,964 † (1) % of total investments as of March 31, 2021. Consumer Discretionary—25.3% fuboTV, Inc. 315,350 6,976 (1) NVIDIA Corp. 107,000 57,131 Airbnb, Inc. Class A 91,100 17,121 (1) Amazon.com, Inc.(1) 15,200 47,030 Okta, Inc. 235,575 51,928 (1) Paylocity Holding Chegg, Inc. 322,325 27,610 (1) (1) Corp. 110,750 19,916 Chewy, Inc. Class A 340,400 28,835 (1) Fiverr International PayPal Holdings, Inc. 198,850 48,289 Ltd.(1) 27,650 6,005 QUALCOMM, Inc. 204,050 27,055 RingCentral, Inc. Lululemon Athletica, (1) (1) Class A 129,800 38,665 Inc. 41,690 12,787 (1) (1) ServiceNow, Inc. 78,325 39,171 MercadoLibre, Inc. 48,225 70,994 (1) Peloton Interactive, Inc. Shopify, Inc. Class A 78,200 86,528 (1) Snowflake, Inc. Class A 336,850 37,876 (1) Tesla, Inc.(1) 162,740 108,699 Class A 110,700 25,381 Sprout Social, Inc. -
UUCEF's Reported Holdings
Unitarian Universalist Common Endowment Fund, LLC "Top 50" Holdings and Summary Report as of December 31, 2020 Asset Name Shares Market Value SEA LTD ADR 7,505 1,493,870.25 NETFLIX COM INC 2,450 1,324,788.50 SQUARE INC A 5,910 1,286,252.40 VISA INC CLASS A SHARES 5,780 1,264,259.40 SERVICENOW INC 2,045 1,125,629.35 AMAZON COM INC 325 1,058,502.25 MATCH GROUP INC NEW 6,468 977,896.92 UBER TECHNOLOGIES INC 18,435 940,185.00 TWILIO INC A 2,220 751,470.00 ADOBE INC 1,490 745,178.80 FACEBOOK INC CLASS A 2,562 699,835.92 ZOETIS INC 3,828 633,534.00 INTUIT INC 1,665 632,450.25 J P MORGAN CHASE CO 4,953 629,377.71 ALIGN TECHNOLOGY INC 1,165 622,552.70 CHARTER COMMUNICATIONS INC NEW 863 570,917.65 COSTAR GROUP INC 602 556,416.56 BERKSHIRE HATHAWAY INC CL B 2,348 544,430.76 ZILLOW GROUP INC C 3,700 480,260.00 WALT DISNEY CO THE 2,541 460,378.38 WARNER MUSIC GROUP CORP CL A 11,890 451,701.10 BANK OF AMERICA CORP 14,865 450,558.15 TDK CORP 2,800 421,444.14 FLOOR DECOR HOLDINGS INC A 4,485 416,432.25 PFIZER INC 11,239 413,707.59 UNILEVER PLC-SPONSORED ADR 6,655 401,695.80 ROCHE HLDG LTD SPONSORED ADR 9,145 399,599.01 ING GROEP N.V. 42,390 396,310.28 ILLUMINA INC 1,045 386,650.00 ISHARES RUSSELL 1000 VALUE ETF 2,820 385,578.60 SAMPO PLC 8,930 377,722.24 DAIKIN INDUSTRIES 1,700 377,393.58 AXA SA SPONSORED ADR 15,395 367,538.84 INFINEON TECHNOLOG 9,155 351,618.23 AIA GROUP LTD 28,599 350,394.32 VERIZON COMMUNICATIONS INC 5,947 349,386.25 SCHNEIDER ELECTRIC 2,375 343,771.67 ATLASSIAN CORP PLC CLASS A 1,450 339,111.50 VONOVIA SE 4,590 335,617.81 ORSTED