PG329: Salicylamide

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the art and science of smart patch testingTM PG329: Salicylamide CAS#: 65-45-2 Patient Information Your patch test result indicates that you have a contact allergy to salicylamide. This contact allergy may cause your skin to react when it is exposed to this substance although it may take several days for the symptoms to appear. Typical symptoms include redness, swelling, itching, and fluid-filled blisters. Where is salicylamide found? This substance is a non-prescription drug with medicinal uses similar to Aspirin. How can you avoid contact with salicylamide? Avoid products that list any of the following names in the ingredients: 2-Carbamoylphenol Cymidon (VAN) 2-Carboxamidophenol Dolomide 2-Hydroxybenzamide Dropsprin 4-10-00-00169 (Beilstein Handbook EINECS 200-609-3 Reference) Eggosalil AI3-03454 Flarpirina Acket H.P. 34 Afko-Sal HSDB 227 Algamon Liquiprin Algiamida Morsarinas Allevin NSC 3115 Amid kyseliny salicylove Novecyl Amid kyseliny salicylove [Czech] OHB Amid-Sal Oramid Amidosal Panithal Anamid Raspberin Andasol SR 4326 BRN 0742439 Salamid Benesal Salamide Benesal (VAN) Saliamid Benzamide, 2-hydroxy- Saliamin Benzamide, o-hydroxy- Salicilamida Benzoic acid, 2-hydroxy-, amide Salicilamida [INN-Spanish] CCRIS 6045 Salicilamide Cetamide Salicilamide [DCIT] Cymidon Salicilamide [Italian] Salicim Salizell (VAN) Salicylamide Salrin Salicylamidum Salymid Salicylamidum [INN-Latin] Serramida Salicylic acid amide UNII-EM8BM710ZC Salipur Urtosal Salizell o-Hydroxybenzamide What are some products that may contain salicylamide? BC Powder Medicaments *For additional information about products that might contain salicylamide, go to the Household Product Database online (http:/householdproducts.nlm.nih.gov) at the United States National Library of Medicine. These lists are brief and provide just a few examples. They are not comprehensive. Product formulations also change frequently. Read product labels carefully and talk to your doctor if you have any questions. These are general guidelines. Talk to your doctor for more specific instructions. .

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Synthesis of Aspirin
SYNTHESIS OF ASPIRIN I. OBJECTIVES AND BACKGROUND You will: synthesize acetylsalicylic acid (aspirin) by carrying out a simple organic reaction, separate your product from the reaction mixture by vacuum filtration, purify your product by recrystallization, perform a chemical test to identify the change in functional group from reactant to product, and determine the success of your synthesis by calculating the percentage yield of your product. INTRODUCTION Aspirin is one of the most widely used medications in the world. It is employed as an analgesic (pain relief), an anti-pyretic (fever control) and an anti-inflammatory. More recently, studies have indicated that daily intake of small doses of aspirin can lower the risk of heart attack and stroke in high-risk patients. The history of aspirin and its precursor dates back to ancient times. Documents attributed to Hippocrates, the father of modern medicine, from the 4th century B.C. refer to the alleviation of pain by chewing on the bark of a willow tree or ingesting a powder made from the bark and leaves of the willow. This remedy was passed on from generation to generation. Fast forward now to the 19th century, where the field of organic chemistry began to experience tremendous growth. By 1838, chemists had managed to isolate, purify and identify the component of willow bark that provided the analgesic benefit. The compound was named salicylic acid, which was based on the genus name of the willow. Efforts to market salicylic acid met with failure, due to an unfortunate side effect-- prolonged ingestion of salicylic acid led to stomach pain, and in some cases, ulcers.
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2 Pharmacology 3 Toxicity and Drug Safety 4 Clinical Applications Of
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