DOCSLIB.ORG

Relationship Between Clinical and Magnetic

Total Page：16

File Type：pdf, Size：1020Kb

Download full-text PDF Read full-text
Relationship Between Clinical and Magnetic 123_Koh_Petersson.qxp 4/7/09 2:53 PM Page 123 Relationship Between Clinical and Magnetic Resonance Imaging Diagnoses and Findings in Degenerative and Inflammatory Temporomandibular Joint Diseases: A Systematic Literature Review Kwang-Joon Koh, DDS Aim: To describe evidence for a relationship between diagnoses Professor and findings of clinical examination and diagnoses and findings of Department of Oral and Maxillofacial magnetic resonance imaging (MRI) examination for degenerative Radiology and inflammatory temporomandibular joint diseases. Methods: School of Dentistry PubMed and the Cochrane Library were searched using specific Chonbuk National University indexing terms and reference lists were hand-searched. Included Korea publications satisfied pre-established criteria. Primary studies were Thomas List, DDS, Odont Dr interpreted using a modification of the Quality Assessment of Professor Diagnostic Accuracy Studies (QUADAS) tool. Results: The litera- Department of Stomatognathic ture search yielded 219 titles and abstracts. Eighty-two studies Physiology were selected and read in full-text. After data extraction and inter- pretation with the QUADAS tool, 23 studies remained. There was Arne Petersson, DDS, Odont Dr a vast heterogeneity in study design, clinical examination methods, Professor and diagnostic criteria. No clear evidence was found for a rela- Department of Oral and Maxillofacial tionship between clinical and MRI diagnoses and findings. Several Radiology studies reported a relationship between clinical pain and internal derangements diagnosed with MRI, but the calculated odds ratio Madeleine Rohlin, DDS, Odont Dr Professor (OR) for this relationship was generally low (1.54–2.04). ORs for Department of Oral and Maxillofacial the relationship between pain and disc displacement without Radiology reduction (4.82) or between crepitation and disc displacement without reduction (3.71) were higher. Conclusion: This review Faculty of Odontology reveals a need for studies with improved quality in reporting of Malmö University samples, examination techniques, findings, and definitions and SE-205 06 Malmö rationales for cutoffs, categories, and diagnoses. We recommend Sweden that standardized protocols such as the Research Diagnostic Criteria for temporomandibular disorders (RDC/TMD) and the Correspondence to: Standards for Reporting of Diagnostic Accuracy (STARD) state- Prof Arne Petersson ment be implemented in future studies. J OROFAC PAIN Faculty of Odontology Malmö University 2009;23:123–139 SE - 205 06 Malmö Sweden Key words: clinical examination, internal derangement, Fax: +46 40 6658549 magnetic resonance imaging, pain, Email: [email protected] temporomandibular disorders linical examination and an imaging technique are fre- quently applied together to diagnose temporomandibular Cdisorders (TMD). The clinical examination assesses mandibular range of motion and associated pain, joint sounds, and muscle and joint tenderness (through palpation). Some findings vary from one assessment to the next in the same individual since TMD can be a transient or recurrent condition. In 1992, Dworkin and LeResche proposed the Research Diagnostic Criteria (RDC) for TMD so that diagnostic categories would be standardized and replicated in clinical research.1 The RDC/TMD involves guidelines and procedures that allow examiners to achieve acceptable levels Journal of Orofacial Pain 123 123_Koh_Petersson.qxp 4/7/09 2:53 PM Page 124 Koh et al of inter-observer reliability with operationalized Medical Subject Headings (MeSH) Definitions of diagnostic criteria for investigating muscle pain, the Terms Used in the Literature Search disc displacements, and degenerative diseases of the temporomandibular joint (TMJ). • Temporomandibular Joint: An articulation An imaging examination is indicated when addi- between the condyle of the mandible and the tional information on a patient’s status is needed articular tubercle of the temporal bone. Year to substantiate results of the clinical examination introduced: 1997 to facilitate clinical decision-making. Because mag- • Magnetic Resonance Imaging (MRI): Non-inva- netic resonance imaging (MRI) defines hard and sive method of demonstrating internal anatomy soft tissue, this technique has gradually replaced based on the principle that atomic nuclei in a other imaging techniques in the examination of the strong magnetic field absorb pulses of radiofre- TMJ. MRI is reported to be the most accurate quency energy and emit them as radio waves, imaging technique for diagnosing the disc position which can be reconstructed into computerized of the TMJ2 and presents osseous changes of the images. The concept includes proton spin tomo- TMJ with high accuracy.3 A recent systematic lit- graphic techniques. Year introduced: 1988 erature review of the diagnostic efficacy of MRI found that evidence was insufficient and that high- Various definitions of pain (spontaneous, at rest, quality studies on the diagnostic efficacy of TMJ at motion, number of motions), tenderness on pal- imaging are needed.4 This review4 focused on stud- pation (at lateral pole, posterior aspects of TMJ), ies of MRI efficacy per se. Such studies are limited joint sounds (clicking, crepitus), and mouth open- because they do not mimic clinical practice: MRI ing capacity were the clinical findings used to of the TMJ is often performed after the clinical determine which studies were relevant for the examination and should underpin the results of the review. clinical examination. But some data indicate a dis- parity in the diagnosis and findings of the clinical Plan for Literature Search examination and the MRI examination.5,6 Therefore, the aim of this systematic literature Table 1 presents the indexing terms and limits review was to describe evidence for a relationship used in the search. Inclusion criteria were that the between clinical findings and diagnoses and MRI publication should describe (i) a clinical diagnosis findings and diagnoses in degenerative and inflam- or finding and an MRI diagnosis or finding in the matory TMJ diseases. Intended readers are clini- assessment of degenerative or inflammatory TMJ cians who treat patients with pain and dysfunction diseases and (ii) a relationship between diagnoses of the temporomandibular region, radiologists, or findings of a clinical examination and of MRI. and related field professionals. Exclusion criteria were studies that (i) reported clinical findings of muscle disorders, not TMD, (ii) reported laboratory findings instead of patient Materials and Methods clinical findings or MRI findings, (iii) investigated TMJ tumors, trauma, and synovial chondroma- This literature review used the systematic tosis, (iv) were case reports, and (v) evaluated other approach of Goodman7 and comprised these steps: TMJ imaging techniques such as arthrography, (1) problem specification, (2) formulation of a arthrotomography, arthroscopy, ultrasonography, plan for the literature search, (3) literature search and scintigraphy. and retrieval of publications, and (4) data extrac- tion, interpretation of data, and evaluation of evi- Literature Search and Retrieval of Publications dence from the literature retrieved. Table 1 illustrates the first step in the search of the Problem Specification PubMed electronic database. Two authors inde- pendently read the title and abstract of all publi- In the diagnosis of degenerative and inflammatory cations that matched the MeSH search terms. TMJ diseases: When at least one author considered a publication relevant, it was ordered and read in full-text. The • What is the evidence for a relationship between Cochrane Database of Systematic Reviews (the clinical and MRI diagnoses? Cochrane Library) was searched using the search • What is the evidence for a relationship between term “temporomandibular joint.” clinical and MRI findings? 124 Volume 23, Number 2, 2009 123_Koh_Petersson.qxp 4/7/09 2:53 PM Page 125 Koh et al The second step of the search was a hand-search Table 1 PubMed Search Strategy and Number of of the reference lists of publications included in the Retrieved Publications first step of the search as described in Fig 1. Reference lists of review articles were also hand- Indexing term Publications (n) searched. Titles were searched for those that con- #1 Temporomandibular joint [MeSH] 1,122 tained the terms (1) magnetic resonance imaging, #2 Magnetic resonance imaging [MeSH] 23,163 MR, or MRI together with temporomandibular #3 #1 AND #2 172 Publication date: 1988/01/01 to 2007/12/31. Database search date: joint or (2) words suggesting a clinical examina- 2007/12/31. tion method or clinical finding such as pain, Limits: (1) Adult subjects: 19+ years; (2) Items with abstract; (3) English; (4) Human; (5) Clinical trial, meta analysis, practice guideline, randomized mouth opening capacity, joint sound, clicking, or controlled trial, review, or comparative study. crepitus/crepitation together with temporo- mandibular joint. No publication date limits were specified in this step. The inclusion and exclusion criteria in the first step were used in the hand- search. Book chapters and reviews were excluded because the focus of the review was primary stud- PubMed search (n = 172 abstracts)A ies. Abstracts of the selected references were ordered. The publication was ordered in full-text Abstracts excluded (n = 108) when (1) there was no abstract or (2) at least one Agreement between two authors 78% author considered an abstract relevant. Full text publicationsB (n = 64) Data
Load more

Recommended publications
  • Synovial Fluidfluid 11
    LWBK461-c11_p253-262.qxd 11/18/09 6:04 PM Page 253 Aptara Inc CHAPTER SynovialSynovial FluidFluid 11 Key Terms ANTINUCLEAR ANTIBODY ARTHROCENTESIS BULGE TEST CRYSTAL-INDUCED ARTHRITIS GROUND PEPPER HYALURONATE MUCIN OCHRONOTIC SHARDS RHEUMATOID ARTHRITIS (RA) RHEUMATOID FACTOR (RF) RICE BODIES ROPE’S TEST SEPTIC ARTHRITIS Learning Objectives SYNOVIAL SYSTEMIC LUPUS ERYTHEMATOSUS 1. Define synovial. VISCOSITY 2. Describe the formation and function of synovial fluid. 3. Explain the collection and handling of synovial fluid. 4. Describe the appearance of normal and abnormal synovial fluids. 5. Correlate the appearance of synovial fluid with possible cause. 6. Interpret laboratory tests on synovial fluid. 7. Suggest further testing for synovial fluid, based on preliminary results. 8. List the four classes or categories of joint disease. 9. Correlate synovial fluid analyses with their representative disease classification. 253 LWBK461-c11_p253-262.qxd 11/18/09 6:04 PM Page 254 Aptara Inc 254 Graff’s Textbook of Routine Urinalysis and Body Fluids oint fluid is called synovial fluid because of its resem- blance to egg white. It is a viscous, mucinous substance Jthat lubricates most joints. Analysis of synovial fluid is important in the diagnosis of joint disease. Aspiration of joint fluid is indicated for any patient with a joint effusion or inflamed joints. Aspiration of asymptomatic joints is beneficial for patients with gout and pseudogout as these fluids may still contain crystals.1 Evaluation of physical, chemical, and microscopic characteristics of synovial fluid comprise routine analysis. This chapter includes an overview of the composition and function of synovial fluid, and laboratory procedures and their interpretations.
    [Show full text]
  • T Helper Cell Infiltration in Osteoarthritis-Related Knee Pain
    Journal of Clinical Medicine Article T Helper Cell Infiltration in Osteoarthritis-Related Knee Pain and Disability 1, 1, 1 1 Timo Albert Nees y , Nils Rosshirt y , Jiji Alexander Zhang , Hadrian Platzer , Reza Sorbi 1, Elena Tripel 1, Tobias Reiner 1, Tilman Walker 1, Marcus Schiltenwolf 1 , 2 2 1, 1, , Hanns-Martin Lorenz , Theresa Tretter , Babak Moradi z and Sébastien Hagmann * z 1 Clinic for Orthopedics and Trauma Surgery, Center for Orthopedics, Trauma Surgery and Spinal Cord Injury, Heidelberg University Hospital, Schlierbacher Landstr. 200a, 69118 Heidelberg, Germany; [email protected] (T.A.N.); [email protected] (N.R.); [email protected] (J.A.Z.); [email protected] (H.P.); [email protected] (R.S.); [email protected] (E.T.); [email protected] (T.R.); [email protected] (T.W.); [email protected] (M.S.); [email protected] (B.M.) 2 Department of Internal Medicine V, Division of Rheumatology, Heidelberg University Hospital, Im Neuenheimer Feld 410, 69120 Heidelberg, Germany; [email protected] (H.-M.L.); [email protected] (T.T.) * Correspondence: [email protected]; Tel.: +49-622-1562-6289; Fax: +49-622-1562-6348 These authors contributed equally to this study. y These authors share senior authorship. z Received: 16 June 2020; Accepted: 23 July 2020; Published: 29 July 2020 Abstract: Despite the growing body of literature demonstrating a crucial role of T helper cell (Th) responses in the pathogenesis of osteoarthritis (OA), only few clinical studies have assessed interactions between Th cells and OA—related symptoms.
    [Show full text]
  • Joint Pain and Sjögren’S Syndrome
    Joint Pain and Sjögren’s Syndrome Alan N. Baer, MD, FACP Alan N. Baer, MD, FACP Associate Professor of Medicine Division of Rheumatology Johns Hopkins University School of Medicine Director, Jerome Greene Sjogren's Syndrome Clinic 5200 Eastern Avenue Mason F. Lord Bldg. Center Tower Suite 4100, Room 413 Baltimore MD 21224 Phone (410) 550-1887 Fax (410) 550-6255 In 1930, Henrik Sjögren, a Swedish ophthalmologist, examined a woman with rheumatoid arthritis who had extreme dryness of her eyes and mouth and filamentary keratitis, an eye condition related to her lack of tears (1). He became fascinated by this unusual debilitating condition and subsequently evaluated 18 additional women with the same combination of findings. He described this new syndrome as “keratoconjunctivitis sicca” in his postdoctoral thesis. Thirteen of the 19 women had chronic inflammatory arthritis. We would now classify these 13 women as having secondary Sjögren’s syndrome (SS), occurring in the context of rheumatoid arthritis. However, joint pain constitutes one of the most common symptoms of the primary form of SS, defined as SS occurring in the absence of an underlying rheumatic disease. In a recent survey of SS patients belonging to the French Sjögren’s Syndrome Society (Association Française du Gougerot-Sjögren et des Syndromes Secs), 81% reported significant joint and muscle pain (2). In this article, the joint manifestations of primary SS will be reviewed. A few definitions are needed for the reader. Although the term “arthritis” was originally applied to conditions causing joint inflammation, it now includes disorders in which the joint has become damaged by degenerative, metabolic, or traumatic processes.
    [Show full text]
  • Detection of Non-Traumatic Knee Effusion Among Asymptomatic
    al of Arth rn ri u ti o s J Swe et al., J Arthritis 2018, 7:2 Journal of Arthritis DOI: 10.4172/2167-7921.1000270 ISSN: 2167-7921 Research Article Open Access Detection of Non-Traumatic Knee Effusion among Asymptomatic Individual with Different type of Lifestyle and Selected Sociodemographic Factors Using Fluid Shift Test and Ultrasonography Myint Swe1*, Ramani Subramanium2, Sabridah Ismail3 and Biju Benjamin4 1Department of Orthopaedics, Royal College of Medicine Perak, University Kuala Lumpur, Malaysia 2Department of Radiology, Royal College of Medicine Perak, University Kuala Lumpur, Malaysia 3Department of Public Health, Royal College of Medicine Perak, University Kuala Lumpur, Malaysia 4Department of Orthopaedics and Trauma surgery, University College London Hospital, 235, Euston Road, London, UK *Corresponding author: Myint Swe, Associate professor, Royal College of Medicine Perak Orthopaedic unit, Surgical based department, 28, Lebuh Sungai Senam, Taman Ipoh, Perak 31400, Malaysia, Tel: +60163445106; +6052432635; Fax: 6052536637; E-mail: [email protected] Received date: March 21, 2018; Accepted date: April 05, 2018; Published date: April 09, 2018 Copyright: © 2018 Swe M, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. Abstract Background history: Non-traumatic knee effusion might be the result of overuse leading to wear and tear processes or systemic diseases. Knee effusion-synovitis was a predictive of some structural abnormalities in the joint suggesting a potential role in early osteoarthritis changes. It is postulated that the active life style with prolonged standing hours predisposed for the increase prevalence of non-traumatic knee effusion even in the young age.
    [Show full text]
  • Limping Child
    Case Report, Wolf et al Limping Child a b Molly Wolf, M.D. , Joseph Makris, M.D. a University of Massachusetts Medical School, Worcester, MA b Department of Radiology, UMass Memorial Children’s Medical Center, Worcester, MA Case Presentation A previously healthy 27-month-old boy presented with a 3-day history of worsening right hip pain, fever of 103.1oF, decreased oral intake, and irritability. The patient recently recovered from an upper respiratory tract infection, but otherwise had no significant past medical history. On physical exam, the patient was unable to bear weight on the right leg and had decreased range of motion due to pain. Ultrasound detected a right hip joint effusion (Fig. 1A). The patient subsequently underwent aspiration and drainage of the right hip joint. Synovial fluid had an elevated white blood cell (WBC) count of 176,500/ mm3. Further analysis of the patient’s blood revealed an elevated WBC count, C reactive protein (CRP), and erythrocyte sedimentation rate (ESR). Culture from the synovial fluid subsequently grew Streptococcus Pneumoniae. MRI performed after the joint aspiration was significant for a small amount of residual joint fluid and normal bone marrow signal (Fig. 1B). Figure 1. (Above): (A) Sagittal ultrasound images of the right and left hips demonstrate a right hip joint effusion; the left side is normal. There is some debris within the right hip joint fluid; although not diagnostic, this raises the suspicion for septic arthritis. (B) FS T2 weighted image from an MRI of the right hip obtained after incision and drainage is significant for small residual right hip joint effusion, normal bone marrow signal, and no abscess.
    [Show full text]
  • Knee Osteoarthritis: a Review of Pathogenesis and State-Of-The-Art Non-Operative Therapeutic Considerations
    G C A T T A C G G C A T genes Review Knee Osteoarthritis: A Review of Pathogenesis and State-Of-The-Art Non-Operative Therapeutic Considerations Dragan Primorac 1,2,3,4,5,6,7,8,9,* , Vilim Molnar 1,6 , Eduard Rod 1,6, Željko Jeleˇc 1,6,10 , Fabijan Cukeljˇ 1,4, Vid Matiši´c 1, Trpimir Vrdoljak 1,11, Damir Hudetz 1,6,11 , Hana Hajsok 1,12 and Igor Bori´c 1,4,7,9 1 St. Catherine Specialty Hospital, 49210 Zabok/10000 Zagreb, Croatia; [email protected] (V.M.); [email protected] (E.R.); [email protected] (Ž.J.); [email protected] (F.C.);ˇ [email protected] (V.M.); [email protected] (T.V.); [email protected] (D.H.); [email protected] (H.H.); [email protected] (I.B.) 2 Eberly College of Science, The Pennsylvania State University, University Park, State College, PA 16802, USA 3 The Henry C. Lee College of Criminal Justice and Forensic Sciences, University of New Haven, West Haven, CT 06516, USA 4 Medical School, University of Split, 21000 Split, Croatia 5 School of Medicine, Faculty of Dental Medicine and Health, University “Josip Juraj Strossmayer”, 31000 Osijek, Croatia 6 School of Medicine, JJ Strossmayer University of Osijek, 31000 Osijek, Croatia 7 Medical School, University of Rijeka, 51000 Rijeka, Croatia 8 Medical School REGIOMED, 96 450 Coburg, Germany 9 Medical School, University of Mostar, 88000 Mostar, Bosnia and Herzegovina 10 Department of Nursing, University North, 48 000 Varaždin, Croatia 11 Department of Orthopedics, Clinical Hospital “Sveti Duh”, 10000 Zagreb, Croatia 12 Medical School, University of Zagreb, 10000 Zagreb, Croatia * Correspondence: [email protected]; Tel.: +385-98-470-710 Received: 20 May 2020; Accepted: 23 July 2020; Published: 26 July 2020 Abstract: Being the most common musculoskeletal progressive condition, osteoarthritis is an interesting target for research.
    [Show full text]
  • Hemarthrosis Detected by Emergency Department Point of Care Ultrasound
    Visual Journal of Emergency Medicine 15 (2019) 100491 Contents lists available at ScienceDirect Visual Journal of Emergency Medicine journal homepage: www.elsevier.com/locate/visj Visual Case Discussion Hemarthrosis detected by Emergency Department Point of Care Ultrasound T (POCUS) in a patient with an anterior dislocation of the humeral head ⁎ Ryan Luevanosa,b, Brianna Wilsonb, Diana Mora-Monteroa,b, a University of Central Florida, College of Medicine, Department of Emergency Medicine, North Florida Regional Medical Center, Gainesville, Fl, USA b Department of Emergency Medicine, North Florida Regional Medical Center, Gainesville, Fl, USA ARTICLE INFO Keywords: Ultrasound Hemarthrosis Joint effusion Shoulder dislocation Point of Care Ultrasound (POCUS) An 88-year-old female was brought to the emergency department right shoulder joint effusion, concerning for hemarthrosis (Fig. 1). for a 3-day history of progressive right shoulder pain and swelling. She Later, a shoulder CT study revealed an anteroinferior subluxation of the reported the pain began after lifting her arm. She denied any recent humeral head with subacromial, subdeltoid and subcoracoid bursal trauma or falls but had a right shoulder dislocation several months fluid. During procedural sedation, her shoulder was successfully re- prior. On physical examination she had normal vital signs, a large right duced. Arthrocentesis was eventually performed by orthopedic surgery, shoulder effusion, soft tissue swelling, crepitus, and painful rangeof confirming hemarthrosis.1–3 motion. A plain radiograph of the shoulder showed anterior dislocation of the humeral head and bedside ultrasound showed a heterogenous Appendix A. Supporting information Supplementary data associated with this article can be found in the online version at doi:10.1016/j.visj.2018.08.012.
    [Show full text]
  • Defining the Inherent Stability of Degenerative Spondylolisthesis: a Systematic Review
    SPINE LITERATURE REVIEW J Neurosurg Spine 23:178–189, 2015 Defining the inherent stability of degenerative spondylolisthesis: a systematic review Andrea M. Simmonds, MD, FRCSC,1 Y. Raja Rampersaud, MD, FRCSC,2 Marcel F. Dvorak, MD, FRCSC,1 Nicolas Dea, MD, MSc, FRCSC,3 Angela D. Melnyk, MASc,1 and Charles G. Fisher, MD, MHSc, FRCSC1 1Department of Orthopaedics, Division of Spine, University of British Columbia, Vancouver, British Columbia; 2Division of Orthopaedic Surgery, Toronto Western Hospital, University Health Network, University of Toronto, Ontario; and 3Division of Neurosurgery, Department of Surgery, Université de Sherbrooke, Quebec, Canada OBJECT A range of surgical options exists for the treatment of degenerative lumbar spondylolisthesis (DLS). The cho- sen technique inherently depends on the stability of the DLS. Despite a substantial body of literature dedicated to the outcome analysis of numerous DLS procedures, no consensus has been reached on defining or classifying the disorder with respect to stability or the role that instability should play in a treatment algorithm. The purpose of this study was to define grades of stability and to develop a guide for deciding on the optimal approach in surgically managing patients with DLS. METHODs The authors conducted a qualitative systematic review of clinical or biomechanical analyses evaluating the stability of and surgical outcomes for DLS for the period from 1990 to 2013. Research focused on nondegenerative forms of spondylolisthesis or spinal stenosis without associated DLS was excluded. The primary extracted results were clinical and radiographic parameters indicative of DLS instability. RESULTs The following preoperative parameters are predictors of stability in DLS: restabilization signs (disc height loss, osteophyte formation, vertebral endplate sclerosis, and ligament ossification), no disc angle change or less than 3 mm of translation on dynamic radiographs, and the absence of low-back pain.
    [Show full text]
  • Progressive Shoulder Arthropathy Ann Rheum Dis: First Published As 10.1136/Ard.54.3.168 on 1 March 1995
    168 Annals ofthe Rheumatic Diseases 1995; 54: 168-173 CASE STUDIES IN DIAGNOSTIC IMAGING Series editor: V N Cassar-Pullicino* Progressive shoulder arthropathy Ann Rheum Dis: first published as 10.1136/ard.54.3.168 on 1 March 1995. Downloaded from W C G Peh, K M C Cheung Clinical history changes ofthe humeral head, with involvement An 84 year old Chinese woman presented with of the bony glenoid. There was increase in a one year history of increasingly severe right the amount of bony debris surrounding the shoulder pain, associated with joint stiffness. shoulder joint (fig 2). Her erythrocyte sedi- There were no symptoms related to the rest of mentation rate was increased (1 15 mm/Ist h). the upper limb or neck. On examination, a soft Computed tomography (CT) confirmed tissue mass was palpable over the anterior aspect destruction of the articulating surfaces of the of the right shoulder. The mass measured glenohumeral joint, with erosions of the about 6 cm in diameter, was generally ill- adjacent humeral head and lateral scapula. defined, soft in consistency, non-tender and Multiple bony fragments were present within cold to touch. Right shoulder movements were the joint space. The deltoid and subscapularis severely restricted in all directions because of muscles were enlarged and swollen. They Department of severe pain. The other peripheral joints had contained hypodense areas which showed Diagnostic Radiology, satisfactory ranges of motion. Her general peripheral ring like enhancement after contrast The University of condition was otherwise satisfactory, with no injection. The space within the remnant gleno- Hong Kong, Queen Mary Hospital, other systemic abnormality evident.
    [Show full text]
  • VA/Dod CLINICAL PRACTICE GUIDELINE for OSTEOARTHRITIS
    VA/DoD CLINICAL PRACTICE GUIDELINE FOR THE NON-SURGICAL MANAGEMENT OF HIP & KNEE OSTEOARTHRITIS Department of Veterans Affairs Department of Defense QUALIFYING STATEMENTS The Department of Veterans Affairs and the Department of Defense guidelines are based upon the best information available at the time of publication. They are designed to provide information and assist decision-making. They are not intended to define a standard of care and should not be construed as one. Neither should they be interpreted as prescribing an exclusive course of management. This Clinical Practice Guideline is based on a systematic review of both clinical and epidemiological evidence. Developed by a panel of multidisciplinary experts, it provides a clear explanation of the logical relationships between various care options and health outcomes while rating both the quality of the evidence and the strength of the recommendations. Variations in practice will inevitably and appropriately occur when clinicians take into account the needs of individual patients, available resources, and limitations unique to an institution or type of practice. Every healthcare professional making use of these guidelines is responsible for evaluating the appropriateness of applying them in the setting of any particular clinical situation. These guidelines are not intended to represent TRICARE policy. Further, inclusion of recommendations for specific testing and/or therapeutic interventions within these guidelines does not guarantee coverage of civilian sector care. Additional
    [Show full text]
  • Posttraumatic Chylous Knee Effusion
    The Journal of Rheumatology 2021;xx:xxxx doi:10.3899/jrheum.191050 First Release July 1 2021 Images in Rheumatology Posttraumatic Chylous Knee Effusion Berber de Boer, MD, Robbert J. Goekoop, MD, Hagaziekenhuis, Rheumatology, Den Haag, the Netherlands. Address correspondence to Dr. B. de Boer, Albinusdreef 2, 2600 RC Leiden, the Netherlands. Email: [email protected]. The authors declare no conflicts of interest. Ethics board approval was not required according to the authors’ institution. Patient’s written informed consent to publish the material was obtained. This is a very rare case of posttraumatic chylous joint effu- pain and swelling improved over the next months and did not sion that has been described only a few times before in the reoccur. literature.1,2,3,4,5 In making a diagnosis, the purulent, however milky, aspect of A 64-year-old White woman presented at the outpatient the synovial fluid may lead to a suspicion of septic arthritis with clinic with persistent knee pain for 5 weeks that she related to subsequent antibiotic treatment, whereas chylous joint effusions a fall. Of note in her medical history were limited cutaneous often have a benign course without treatment.3 Microscopy of systemic sclerosis, osteoarthritis, and chondrocalcinosis of both the fluid is key to be able to differentiate the nature of the swollen knees, and a left patella reimplantation 35 years ago. There was joint. no previous history of inflammatory arthritis. On physical exam- ination, she had normal vital signs. There was painful swelling of REFERENCES the left suprapatellar bursa, without warmth or erythema.
    [Show full text]
  • Common Terminology Criteria for Adverse Events (CTCAE) Version 5.0 Published: November 27, 2017
    Common Terminology Criteria for Adverse Events (CTCAE) Version 5.0 Published: November 27, 2017 U.S. DEPARTMENT OF HEALTH AND HUMAN SERVICES Common Terminology Criteria for Adverse Events (CTCAE) v5.0 Publish Date: November 27, 2017 Introduction Grades Grade 5 The NCI Common Terminology Criteria for Grade refers to the severity of the AE. The CTCAE Grade 5 (Death) is not appropriate for some AEs Adverse Events is a descriptive terminology which displays Grades 1 through 5 with unique clinical and therefore is not an option. can be utilized for Adverse Event (AE) reporting. A descriptions of severity for each AE based on this grading (severity) scale is provided for each AE general guideline: Definitions term. A brief Definition is provided to clarify the Grade 1 Mild; asymptomatic or mild meaning of each AE term. A single dash (-) symptoms; clinical or diagnostic indicates a Definition is not available. SOC observations only; intervention System Organ Class (SOC), the highest level of the not indicated. 1 MedDRA hierarchy, is identified by anatomical or Grade 2 Moderate; minimal, local or Navigational Notes physiological system, etiology, or purpose (e.g., noninvasive intervention A Navigational Note is used to assist the reporter SOC Investigations for laboratory test results). indicated; limiting age- in choosing a correct AE. It may list other AEs that CTCAE terms are grouped by MedDRA Primary appropriate instrumental ADL*. should be considered in addition to or in place of SOCs. Within each SOC, AEs are listed and Grade 3 Severe or medically significant but not the AE in question. A single dash (-) indicates a accompanied by descriptions of severity (Grade).
    [Show full text]