Management of Subsequent Pregnancy After an Unexplained Stillbirth
Journal of Perinatology (2010) 30, 305–310 r 2010 Nature Publishing Group All rights reserved. 0743-8346/10 $32 www.nature.com/jp STATE-OF-THE-ART Management of subsequent pregnancy after an unexplained stillbirth SJ Robson1 and LR Leader2 1Department of Obstetrics and Gynaecology, Australian National University, Canberra, Australia and 2School of Women’s and Children’s Health, University of New South Wales, Royal Hospital for Women, Randwick, Australia they face in a subsequent pregnancy, as well as potential Purpose: To review the management of pregnancy after an unexplained management strategies to optimize future pregnancy outcomes.2–4 stillbirth. Unfortunately, as many as one-third of such cases remain Epidemiology: Approximately 1 in 200 pregnancies will end in ‘unexplained’ and unexplained stillbirth is now the commonest stillbirth, of which about one-third will remain unexplained. Unexplained single contributor to perinatal mortality. stillbirth is the largest single contributor to perinatal mortality. There is no evidence that extensive research efforts over the last Subsequent pregnancies do not appear to have an increased risk of two decades have yielded a reduction in the incidence of this 2,5 stillbirth, but are characterized by increased rates of intervention distressing outcome. Virtually all of the published literature is (induction of labor, elective cesarean section) and iatrogenic adverse concerned with population-based strategies for primary prevention outcomes (low birth weight, prematurity, emergency cesarean section and of unexplained stillbirth. However, the commonest situation in post-partum hemorrhage). which clinicians will find themselves is management of women in their next pregnancy after an unexpected unexplained stillbirth. Conclusions: There is no level-one evidence to guide management in Effective care of women in their next pregnancy after an this situation.
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