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Report Fac-Simile Informazioni sui tuoi dati grezzi Nome Bill Whale Whale Codice a barre del kit 000-001-014 Tipo di biomateriale Feci Data di ricezione del campione 20.12.2018 Metodo di analisi Sequenza rRNA 16s Data di redazione del report 01.03.2021 2 Le seguenti informazioni non costituiscono una diagnosi. Discuti i risultati del test con il tuo medico di famiglia. Contenuto del report Confronta i risultati dei test 4 Protezione dalla malattia 5 Diversita del microbioma 11 Tipo di microbioma 12 Probiotici e batteri benefici 14 Batteri patogeni e patogeni opportunisti 27 Fibra alimentare e butirrato 32 Sintesi di vitamine 37 Nazionalità del microbioma 55 Alimenti consigliati 56 Dati grezzi 59 Riferimenti 88 3 Le seguenti informazioni non costituiscono una diagnosi. Discuti i risultati del test con il tuo medico di famiglia. Confronta i risultati dei test Confronta i risultati dei test Codice a barre Raccolta del Disponibilità Varietà Probiotici Fibre Butirrato Anomalia campione del report alimentari 615-065-78 05.08.2018 03.08.2018 8 9 6 9 No 8 000-001-01 20.12.2018 19.02.2018 7 6 6 9 No 4 000-001-01 25.12.2018 19.02.2018 7 10 6 9 No 3 4 Le seguenti informazioni non costituiscono una diagnosi. Discuti i risultati del test con il tuo medico di famiglia. Protezione dalla malattia Protezione dalla malattia I batteri intestinali sono coinvolti nei processi metabolici e infiammatori del corpo. Finora, la ricerca ha identificato i tratti del microbioma e le caratteristiche associate a varie malattie. Se il microbioma non ha queste caratteristiche, significa che il livello di protezione è alto e viceversa. Questo viene valutato su una scala da 1 a 10. Malattia Descrizione Colite ulcerosa La tua composizione batterica rivela normale protezione dalle malattie Obesità La tua composizione batterica rivela alto protezione dalle malattie Coronaropatia La tua composizione batterica rivela alto protezione dalle malattie Malattia di Crohn La tua composizione batterica rivela alto protezione dalle malattie Diabete di tipo 2 La tua composizione batterica rivela alto protezione dalle malattie 5 Le seguenti informazioni non costituiscono una diagnosi. Discuti i risultati del test con il tuo medico di famiglia. Protezione dalla malattia Colite ulcerosa Grado di protezione: 6 di 10 Esistono caratteristiche specifiche del microbioma legate alla colite ulcerosa. In una scala da 1 a 10, meno caratteristiche sono condivise con il tuo microbioma, maggiore è il livello di protezione da questa malattia. I microbiomi dei pazienti con queste malattie hanno livelli inferiori di batteri commensali come Faecalibacterium, Eubacterium, Ruminococcus, Akkermansia e Phascolarctobacterium. Ciò è accompagnato da una maggiore presenza di batteri patogeni chiamati Escherichia coli. Dati grezzi Batteri che partecipano alla sintesi Rappresentazione nel microbioma Effetto Agathobacter 0.24% Aumenta la protezione Lachnospiraceae UCG-001 0.22% Aumenta la protezione Dorea 0.18% Diminuisce la protezione Bifidobacterium 0.18% Diminuisce la protezione Collinsella 0.16% Diminuisce la protezione Unknown Erysipelotrichaceae 0.05% Diminuisce la protezione Parvimonas 0% Diminuisce la protezione Akkermansia 0% Aumenta la protezione Butyrivibrio 0% Aumenta la protezione Corynebacterium group 1 0% Aumenta la protezione 6 Le seguenti informazioni non costituiscono una diagnosi. Discuti i risultati del test con il tuo medico di famiglia. Protezione dalla malattia Obesità Grado di protezione: 8 di 10 La proporzione dei diversi batteri del microbioma influenza l'infiammazione e il rischio di sviluppare l'obesità e altre malattie metaboliche. In una scala da 1 a 10, meno caratteristiche sono condivise con il tuo microbioma, maggiore è il livello di protezione da questa malattia. I batteri Akkermansia muciniphila e Christensenella minuta proteggono dall'obesità. In particolare, il primo è associato a una massa corporea bassa e protegge dai disturbi metabolici e dall'insulino-resistenza. Il microbioma di soggetti con un metabolismo normale è caratterizzato da livelli più elevati di Faecalibacterium e Bifidobacterium. D'altra parte però, i pazienti che soffrono di obesità presentano una maggiore quantità di Bacteroides e Parabacteroides. Inoltre, la presenza di disturbi metabolici è associata alla presenza di Enterobacteriaceae e Desulfovibrionaceae. Dati grezzi Batteri che partecipano alla sintesi Rappresentazione nel microbioma Effetto Eubacterium eligens group 3.11% Aumenta la protezione Escherichia-Shigella 0.93% Diminuisce la protezione Barnesiella 0.87% Aumenta la protezione UBA1819 0.84% Diminuisce la protezione Papillibacter 0.5% Aumenta la protezione Ruminiclostridium group 9 0.35% Aumenta la protezione Coprococcus 3 0.21% Diminuisce la protezione Collinsella 0.16% Diminuisce la protezione Haemophilus 0.01% Aumenta la protezione Unknown Prevotellaceae 0% Diminuisce la protezione 7 Le seguenti informazioni non costituiscono una diagnosi. Discuti i risultati del test con il tuo medico di famiglia. Protezione dalla malattia Coronaropatia Grado di protezione: 8 di 10 Esistono caratteristiche specifiche del microbioma legate all'aterosclerosi (ispessimento delle arterie) e alla malattia a essa associata, la cardiopatia coronarica. In una scala da 1 a 10, meno caratteristiche sono condivise con il tuo microbioma, maggiore è il livello di protezione da questa malattia. Batteri come Proteus, Lachnoclostridium e Providencia producono trimetilammina (TMA) da colina (presente nei tuorli d'uovo) e L-carnitina (presente nella carne rossa e nel pesce). La TMA viene assorbita dal fegato e ossidata in trimetilammina-N-ossido (TMAO). Questo composto è associato a un rischio maggiore di aterosclerosi e cardiopatia coronarica. Dati grezzi Batteri che partecipano alla sintesi Rappresentazione nel microbioma Effetto Unknown Lachnospiraceae 20.56% Diminuisce la protezione Blautia 2.26% Aumenta la protezione Anaerostipes 0.92% Aumenta la protezione UBA1819 0.84% Diminuisce la protezione Eubacterium hallii group 0.78% Aumenta la protezione Papillibacter 0.5% Aumenta la protezione Collinsella 0.16% Diminuisce la protezione Turicibacter 0.06% Aumenta la protezione Veillonella 0.01% Diminuisce la protezione Megasphaera 0% Diminuisce la protezione 8 Le seguenti informazioni non costituiscono una diagnosi. Discuti i risultati del test con il tuo medico di famiglia. Protezione dalla malattia Malattia di Crohn Grado di protezione: 9 di 10 Esistono caratteristiche specifiche del microbioma legate alla malattia di Crohn. In una scala da 1 a 10, meno caratteristiche sono condivise con il tuo microbioma, maggiore è il livello di protezione da questa malattia. La malattia di Crohn è associata a un aumento dei livelli di Escherichia coli. Questi batteri partecipano ai processi infiammatori. D'altra parte però, è presente una quantità inferiore di Faecalibacterium prausnitzii, batteri che normalmente proteggono l'intestino dall'infiammazione. Dati grezzi Batteri che partecipano alla sintesi Rappresentazione nel microbioma Effetto Faecalibacterium 15.56% Aumenta la protezione Unknown Ruminococcaceae 2.4% Aumenta la protezione Lachnospira 1.91% Aumenta la protezione Ruminococcus Lachnospiraceae 0.92% Diminuisce la protezione Erysipelotrichaceae UCG-003 0.65% Diminuisce la protezione Phascolarctobacterium 0.47% Aumenta la protezione Streptococcus 0.16% Diminuisce la protezione Eubacterium ruminantium group 0.06% Diminuisce la protezione Haemophilus 0.01% Aumenta la protezione Mitsuokella 0% Diminuisce la protezione 9 Le seguenti informazioni non costituiscono una diagnosi. Discuti i risultati del test con il tuo medico di famiglia. Protezione dalla malattia Diabete di tipo 2 Grado di protezione: 10 di 10 Esistono caratteristiche specifiche del microbioma legate al diabete di tipo II. In una scala da 1 a 10, meno caratteristiche sono condivise con il tuo microbioma, maggiore è il livello di protezione da questa malattia. I batteri Firmicutes producono butirrato, un acido grasso a catena corta che svolge un ruolo antinfiammatorio. I pazienti con diabete di tipo II dispongono di una quantità inferiore di Firmicutes e presentano un rischio maggiore di infiammazione. Presentano anche livelli più bassi di Akkermansia, Haemophilus, Lactobacillus e Paraprevotella. Dati grezzi Batteri che partecipano alla sintesi Rappresentazione nel microbioma Effetto Faecalibacterium 15.56% Aumenta la protezione Anaerostipes 0.92% Aumenta la protezione Erysipelotrichaceae UCG-003 0.65% Aumenta la protezione Lachnospiraceae UCG-001 0.22% Aumenta la protezione Acinetobacter 0.01% Aumenta la protezione Slackia 0% Diminuisce la protezione Victivallis 0% Aumenta la protezione Prevotellaceae NK3B31 group 0% Aumenta la protezione Muribaculum 0% Aumenta la protezione Corynebacterium group 1 0% Aumenta la protezione Rothia 0% Diminuisce la protezione 10 Le seguenti informazioni non costituiscono una diagnosi. Discuti i risultati del test con il tuo medico di famiglia. Diversita del microbioma Diversita del microbioma Il tuo punteggio: 7 di 10 Disponi di un microbioma piuttosto diversificato che può aiutare a resistere all'impatto negativo di fattori esterni. La varietà indica il numero approssimativo di specie batteriche che vivono nell'intestino di un individuo. Ogni tipo di batterio ha le proprie funzioni, che spesso sono complementari. Un microbioma diversificato può svolgere una gamma più ampia di funzioni che regolano e compensano, rendendo l'intero sistema più stabile. Fattori esterni come una cattiva alimentazione o l’assunzione di antibiotici possono far
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