Transcriptional Regulation by Chromatin and RNA Polymerase II Oct

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ASBMB SYMPOSIA SERIES Transcriptional regulation by chromatin and RNA polymerase II Oct. 1 – 5, 2020 | Snowbird, Utah Become a sponsor of the ASBMB “Transcriptional Regulation: Chromatin and RNA Polymerase II,” symposium. It’s the most effective way to reach key decision makers in the fields of transcription, chromatin biology, imaging, genomics and epigenetics. Meeting Highlights 125+ principal investigators, graduate students, postdoctoral fellows, and other researchers 12+ sessions of cutting-edge program with leading researchers Confirmed Invited Speakers Patrick Cramer, Keynote Max Planck Institute, Göttingen, Germany • Steve Buratowski, Harvard • Ibrahim Cisse, MIT • Philip Cole, Harvard • John Lis, Cornell Symposium Organizers • Karolin Luger, UC-Boulder Karen M. Arndt, Univ. of Pittsburgh • Geeta Narlikar, UCSF Dylan J. Taatjes, UC-Boulder • Eva Nogales, UC-Berkeley Y. Jessie Zhang, UT-Austin • Ali Shilatifard, Northwestern • Carl Wu, Johns Hopkins University asbmb.org/meetings-events American Society for Biochemistry and Molecular Biology 11200 Rockville Pike, Suite 302 Rockville, MD 20852-3110 www.asbmb.org ASBMB SYMPOSIA SERIES Transcriptional regulation by chromatin and RNA polymerase II Oct. 1 – 5, 2020 | Snowbird, Utah ASBMB Symposia Sponsorship Levels and Benefits Platinum: $7,001+ All Gold, Silver and Bronze level benefits, plus: • One month of online advertising in any one of ASBMB’s 3 scientific journals or our membership magazine, ASBMB Today. Gold: $5,000+ All Silver and Bronze level benefits, plus: • Full-page, color advertisement included in the meeting program Silver: $2,500+ All Bronze level benefits, plus: • Onsite presence with a small table for literature or tabletop display for duration of meeting. All onsite organization representatives must be registered meeting attendees. • Formal summary of company services & products during symposium opening remarks, to promote attendee interest and table visits during meeting. Bronze: $1,000+ • Logo on meeting website and linked to company webpage • Logo appears in meeting program and sponsor signage on screens during breaks • Sponsor’s brochure or flier displayed on literature table and included in attendee bags Additional options: Supporting Sponsor • Poster receptions • Best poster awards • Opening remarks/closing remarks/receptions • Invited speaker travel sponsorships American Society for Biochemistry and Molecular Biology 11200 Rockville Pike, Suite 302 Rockville, MD 20852-3110 www.asbmb.org.

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Roger D. Kornberg Stanford University, School of Medicin, Fairchild D 123, Stanford, CA 94305-5126, USA
THE MOLECULAR BASIS OF EUKARYOTIC TRANSCRIPTION Nobel Lecture, December 8, 2006 by Roger D. Kornberg Stanford University, School of Medicin, Fairchild D 123, Stanford, CA 94305-5126, USA. I am deeply grateful for the honor bestowed on me by the Nobel Committee for Chemistry and the Royal Swedish Academy of Sciences. It is an honor I share with my collaborators. It is also recognition of the many who have con- tributed over the past quarter century to the study of transcription. THE NUCLEOSOME My own involvement in studies of transcription began with the dis- covery of the nucleosome, the basic unit of DNA coiling in eukaryote chromosomes [1]. X-ray studies and protein chemistry led me to propose the wrapping of DNA around a set of eight histone molecules in the nucleosome (Fig. 1). Some years later, Yahli Lorch and I found this wrapping of DNA prevents the ini- tiation of transcription in vitro [2]. Michael Grunstein and colleagues showed nucleosomes interfere with transcription in vivo [3]. The nuc- leosome serves as a general gene repressor. It assures the inactivity of all the many thousands of genes in eukaryotic cells except those Figure 1. The nucleosome, fundamental whose transcription is brought particle of the eukaryote chromosome. about by specific positive regulatory Schematic shows the coiling of DNA around mechanisms. What are these posi- a set of eight histones in the nucleosome, tive regulatory mechanisms? How is the further coiling in condensed (transcrip- tionally inactive) chromatin, and uncoiling repression by the nucleosome over- for interaction with the RNA polymerase II come for transcription? Our recent (pol II) transcription machinery.
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Patrick Cramer - Curriculum Vitae Page 1
Patrick Cramer - Curriculum vitae page 1 Patrick Cramer – Curriculum vitae (December 07, 2016) Personal data Date of birth February 3, 1969 Place of birth Stuttgart, Germany Nationality German Marital status Married, two children (born 1997, 2000) Address Professor Dr. Patrick Cramer Max Planck Institute for Biophysical Chemistry Department of Molecular Biology Am Fassberg 11 D-37077 Göttingen Contact information Phone: +49 551 201-2800 Email: [email protected] Internet: www.mpibpc.mpg.de/cramer Education 1998 EMBL and Universität Heidelberg Dr. rer. nat. ‘summa cum laude’ 1995 Universität Heidelberg Diploma in Chemistry 7/94-3/95 University of Cambridge, UK Research student with A.R. Fersht 10/92-3/93 University of Bristol, UK ERASMUS research student with A.G. Orpen 1992-1995 Universität Heidelberg Student of Chemistry 1989-1991 Universität Stuttgart Student of Chemistry Positions 2014-now MPI for Biophysical Chemistry Director 2010-2013 Universität München (LMU) Director, Department of Biochemistry 2004-2013 Universität München (LMU) Director, Gene Center Munich 2004-2014 Universität München (LMU) Professor of Biochemistry 2001-2003 Universität München LMU Tenure-track Professor of Biochemistry 1999-2001 Stanford University, USA Postdoctoral fellow with R.D. Kornberg 1995-1998 EMBL Grenoble, France Predoctoral fellow with C.W. Müller Patrick Cramer - Curriculum vitae page 2 Awards and honours 2016 Centenary Award of the British Biochemical Society 2016 Advanced Grant ‘TRANSREGULON’ of the European Research Council (ERC) 2015
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