DOCSLIB.ORG

Available Online Through ISSN 2229-3566

Total Page：16

File Type：pdf, Size：1020Kb

Download full-text PDF Read full-text
Available Online Through ISSN 2229-3566 D Saravanan et al / IJRAP 2011, 2 (1) 216-220 Research Article Available online through www.ijrap.net ISSN 2229-3566 PHARMACOGNOSTIC EVALUATION OF LEAVES OF ALANGIUM SALVIIFOLIUM LINN *1 1 2 1 1 D. Saravanan , J. Padmavathy , M.J. Parimala , I. Aparna Lakshmi , Ch. Praveen 1Ratnam Institute of Pharmacy, Pidathapolur, Nellore-524 346, Andhra Pradesh, India 2Department of Chemistry, SRM College of Pharmacy, Kattankulathur, Chennai – 603 203, Tamil Nadu, India Received on: 14/12/2010 Revised on: 28/01/2011 Accepted on: 09/02/2011 ABSTRACT The leaves of Alangium salviifolium Linn (Family: Alangiaceae) was a reputed drug mentioned in the ancient books of Ayurveda and Siddha for the treatment of epilepsy, jaundice and hepatitis. The investigation was carried out to study the pharmacognostical characteristics of the plant material. The various parameters like macro-morphology, micro-morphology, quantitative microscopy, physicochemical profile, TLC profile, preliminary phytochemical screening and the salient diagnostic features are documented. The characteristic fluorescence analysis was also carried out. The microscopical studies revealed the presence of unicellular trichomes, siphonostele vascular bundle, calcium oxalate crystals, anamocytic stomata. In the phytochemical screening, the extracts were found to have important constituents like carbohydrates, saponins, reducing sugar, alkaloids, phytosterol, fixed oil, tannins and flavanones. The above study would be useful as a diagnostic tool in the identification and authentication of the crude drug. KEYWORDS: Alangium salviifolium Linn., fluorescence analysis, macro-morphology, micro-morphology, anamocytic stomata. *Corresponding Author D. Saravanan. Assistant professor, Dept of pharmaceutical chemistry, Ratnam Institute of Pharmacy, Nellore-524 346, Andhra Pradesh, India. E-mail: [email protected], INTRODUCTION The leaves of Alangium salviifolium Linn are used as Alangium salviifolium Linn (Family: Alangiaceae) astringent, laxative, refrigerant and used to treat commonly known as Shoedhanam in Sanskrit and Akola rheumatism, leprosy, syphilis and asthma8. The root bark in Hindi1 was found distributed in South India, Tropical is used as purgative, astringent, anthelmintic, antipyretic, forest, Burma, Karnataka and widely spread over Tamil expectorant, anti-inflammatory, emetic, diaphoretic, Nadu2. It is a deciduous, rambling shrub or tree, which anticancer, antimicrobial and antitumor agents9,10,11. The grows up to a height of ten meters. The plant flowers root is used as hypotensive agent, anthelmintic and used during February to April and bears fruits during May to in the treatment of biliousness, inflammation and August3,4. Bark is pale brown in colour with shallow snakebite. The bark shows antitubercular activity. The cracks exfoliating in sub corky scales and trunk with fruits are used as laxative, refrigerant, emetic and numerous holes5,6. Leaves are oblong or ovate- antiphlegmatic agent. The presence of alkaloids like lanceolate, more or less acuminate. Flowers are white alangiside, alangidiol, alangicine, alangimarckine, sub-silky, ebracteate, shortly pedicelled, articulated with alamaridines, dimethyl aptaline, iso alamarin, the pedicel. Fruits are ellipsoidal when young and alangimarinone, ankorine, tubulosine, cephaeline, become purplish red, globular when ripen. Fruits are dimethyl phycotrine has been reported earlier12,13. As edible, enclosed in white mucilaginous sweet rather there is no detailed pharmacognostical data reported on astringent pulp7. Seeds are single ovoid (1x0.5 cm) with the leaves, the present study was carried out to develop bony foliaceous endocarp. pharmacognostical data on the leaves which is essential for its standardization and authentication. International Journal of Research in Ayurveda & Pharmacy, 2(1), Jan-Feb 2011 216-220 D Saravanan et al / IJRAP 2011, 2 (1) 216-220 MATERIALS AND METHODS Tropical forest, Burma, Karnataka and widely spread Collection over Tamil Nadu. The leaves of Alangium salviifolium Linn were collected Microscopical analysis of the leaves from Malaipattu near Sriperumbudur, Tamil Nadu, India Transverse section of the leaf shows the dorsiventral during the month of September and was identified by nature. CSRI, Arumbakkam, Chennai. Drug material was Transverse section of petiole powdered and stored at 25°C in an air tight container. Transverse section of petiole shows oval circular outline The chemicals used in the experiments were of analytical as shown in (Fig-2). Epidermis is made up of small grade. Fresh material was shade dried, powdered and rectangular cells and covered by cuticle. Some of the passed through 60 mesh sieve. Fresh leaves were epidermal cells elongate to form unicellular trichomes, preserved in formaldehyde:acetic acid:ethanol (1:1:1) cortex are differentiated into outer 3-5 layers of solution. collenchyma cells and inner 5-8 rows of oval shaped Chemicals and instruments parenchyma cells as shown in (Fig-3). Vascular bundle is Compound microscope, camera lucida (prism type), seen at the centre with parenchyma cells. It is glass slides, cover slips, watch glass and other common represented by a siphonostele. Vessels are circular and glassware’s were the basic apparatus and instruments arranged in a row as multiples of 2-4. Unlignified fibers used for the study. Solvents viz. ethanol (95%) and are present surrounding the vascular bundle. Ground reagents viz. saffranin, glycerin, HCl, chloral hydrate and tissue is made up of parenchyma cells and most of the sodium hydroxide were procured from Ranbaxy Fine cells nearer to the bundles contain traces of calcium Chemicals Ltd., Mumbai, India. oxalate crystals as shown in (Fig-4). Macroscopic and microscopic analysis Transverse section of lamina The macroscopy and microscopy of the leaf were studied Transverse section of lamina shows single layered according to the method of Brain and Turner (1975)14. epidermis, slightly vertically elongated cells, followed by For the microscopical studies, cross sections were 3 rows of columnar, closely arranged palisade tissue. The prepared and stained as per the procedure of Johansen spongy tissue is made up of 4-6 rows of rounded closely (1940)15. Free hand section of leaf materials (midrib, packed cells as shown in (Fig-5). Vascular bundle of the lamina and petiole) was taken and stained with saffranin larger veins is accompanied by thick walled parenchyma followed by concentrated hydrochloric acid. The figures cells as shown in (Fig-5). of section were drawn with the help of Camera Lucida. Epidermis in surface view Physicochemical analysis Adaxial foliar epidermis is imperforate and is composed Physicochemical analysis i.e. percentage of ash values of penta-hexagonal thick walled cells straight margin as and extractive values were performed according to the shown in (Fig-6). The adaxial foliar epidermis is methods prescribed (Indian Pharmacopoeia, 1966; composed of cells with straight to very slightly wavy WHO/QCMMPM, 1992)16,17. Fluorescence analysis was margins as shown in (Fig-7). It is profusely perforated by carried out according to the method of Chase, Pratt anamocytic stomata. (1949) and Kokoski et al. (1958)18,19. The colour and Quantitative measurement consistency of extracts was also noted. Quantitative measurement of leaves of Alangium Preliminary phytochemical screening salviifolium Linn showed the presence of epidermal Preliminary phytochemical screening was carried out by cells, palisade tissue, parenchyma cells, spongy tissue using standard procedures described by Kokate (1986) with anamocytic stomata and unicellular trichome with and Harborne (1998)20,21. blunt end. The results are shown in (Table 1). RESULTS AND DISCUSSION Physicochemical study Macroscopical analysis of the leaves Physicochemical parameters like total ash, water soluble Leaves are simple, partly opposite, penne nerved, leaves ash, acid insoluble ash, water soluble extractive and variable 7.5-12.5 by 2.5-5.7cm, narrowly oblong or alcohol soluble extractive of the leaves of Alangium ovate-lanceolate more or less acuminate, sub ovate, salviifolium Linn are shown in (Table 2). entire, glabrous above pubescent on the leaves and Fluorescence analysis of leaf powder and leaf extracts prominently reticulately veined beneath 4-6 pairs of The fluorescence analysis of the leaves of Alangium lateral veins base rounded or acute as shown in (Fig 1). It salviifolium Linn showed the presence of fluorescence is a deciduous, rambling shrub or tree, which grows up to compounds in both the powders and extracts as shown in a height of 10 meters and is distributed in South India, (Table 3). International Journal of Research in Ayurveda & Pharmacy, 2(1), Jan-Feb 2011 216-220 D Saravanan et al / IJRAP 2011, 2 (1) 216-220 TLC analysis 15. Johansen DA, Plant Microtechnique, New York: McGraw Hill; 1940. The Rf values of various spots on TLC plate performed 16. Indian Pharmacopoeia, Government of India, ministry of health in the experiment is as shown in (Table 4). The extracts and human welfare, New Delhi(India): controller of were studied in different solvent systems over silica gel- publications; 1996; 2: A53-A54. G. 17. WHO/ PHARM/ 92.559/ rev.1., Quality control methods for Preliminary phytochemical study medicinal plant materials, Organisation Mondiale De La Sante, The results of preliminary phytochemical analysis of leaf Geneva, 1992; 9: 22-34. 18. Chase CR, Pratt RJ, Fluorescence of powdered vegetable drugs extracts of Alangium salviifolium
Load more

Recommended publications
  • Shahezan Issani Report Environment and Social Impact Assessment for Road Asset 2020-03-02
    Draft Initial Environmental Examination Project Number: 53376-001 September 2020 IND: DBL Highway Project Prepared by AECOM India Private Limited The initial environmental examination is a document of the borrower. The views expressed herein do not necessarily represent those of ADB's Board of Directors, Management, or staff, and may be preliminary in nature. Your attention is directed to the “Terms of Use” section of this website. In preparing any country program or strategy, financing any project, or by making any designation of or reference to a particular territory or geographic area in this document, the Asian Development Bank does not intend to make any judgments as to the legal or other status of any territory or area. FINAL ESIA Environment and Social Impact Assessment (ESIA) of Road Asset Anandapuram-Pendurthi-Anakapalli Section of NH-16 Dilip Buildcon Limited September 19, 2020 Environment and Social Impact Assessment of Road Asset – Anandapuram – Pendurthi – Ankapalli Section of NH 16, India FINAL Quality information Prepared by Checked by Verified by Approved by Shahezan Issani Bhupesh Mohapatra Bhupesh Mohapatra Chetan Zaveri Amruta Dhamorikar Deepti Bapat Revision History Revision Revision date Details Authorized Name Position 01 23 April 2020 First cut ESIA report without Yes Chetan Zaveri Executive Director monitoring data 02 30 April 2020 Draft ESIA report without monitoring Yes Chetan Zaveri Executive Director data 03 9 July 2020 Final ESIA report with monitoring Yes Chetan Zaveri Executive Director data and air modelling
    [Show full text]
  • Anthelmintic Activity of Alangium Salviifolium Bark
    Available online a t www.scholarsresearchlibrary.com Scholars Research Library J. Nat. Prod. Plant Resour ., 2012, 2 (6):717-720 (http://scholarsresearchlibrary.com/archive.html) ISSN : 2231 – 3184 CODEN (USA): JNPPB7 Anthelmintic activity of Alangium salviifolium bark Ravi Shankar Pandey SLT Institute of Pharmaceutical Sciences, Guru Ghasidas Vishwavidyalaya, Bilaspur, C.G _____________________________________________________________________________________________ ABSTRACT Alangium salviifolium (AS) is a novel medicinal plant used for the treatment of various diseases including helminthiasis by the traditional healers of Chhattisgarh. So an attempt has been taken to explore it scientifically. Preliminary phytochemical investigation reveals that there is presence of flavonoids, Saponins, phenols, bitter principles and steroids. Three different concentrations (50, 100 and 150 mg/ml) of crude extract of hexane, ethyl acetate, chloroform and methanol were tested against earthworms (Pheretima posthuma), which involved the evaluation of paralysis and death period of the worm. Methanol and chloroform extracts exhibited significant anthelmintic activity at highest concentration of 150 mg/mL. Piperzine citrate was selected as standard compound and DMF as control. The anthelmintic activity of Methanol and chloroform of bark of AS has therefore been evaluated for the first time. Key words: Alangium salviifolium; helminthiasis; Pheretima posthuma; Piperzine citrate and Paralysis _____________________________________________________________________________________________ INTRODUCTION Helminthiasis is a macroparasitic disease of humans and animals caused due to parasitic worms such as pinworm, roundworm, or tapeworm. These worms some times live in the gastrointestinal tract, may also burrow into the liver, lymphatic system, or other organs [1]. The clinical picture of consists of skin infection, skin nodules, and ocular lesions. The skin lesions include oedema, papules, scab-like eruptions and altered pigmentation.
    [Show full text]
  • Medicinal Practices of Sacred Natural Sites: a Socio-Religious Approach for Successful Implementation of Primary
    Medicinal practices of sacred natural sites: a socio-religious approach for successful implementation of primary healthcare services Rajasri Ray and Avik Ray Review Correspondence Abstract Rajasri Ray*, Avik Ray Centre for studies in Ethnobiology, Biodiversity and Background: Sacred groves are model systems that Sustainability (CEiBa), Malda - 732103, West have the potential to contribute to rural healthcare Bengal, India owing to their medicinal floral diversity and strong social acceptance. *Corresponding Author: Rajasri Ray; [email protected] Methods: We examined this idea employing ethnomedicinal plants and their application Ethnobotany Research & Applications documented from sacred groves across India. A total 20:34 (2020) of 65 published documents were shortlisted for the Key words: AYUSH; Ethnomedicine; Medicinal plant; preparation of database and statistical analysis. Sacred grove; Spatial fidelity; Tropical diseases Standard ethnobotanical indices and mapping were used to capture the current trend. Background Results: A total of 1247 species from 152 families Human-nature interaction has been long entwined in has been documented for use against eighteen the history of humanity. Apart from deriving natural categories of diseases common in tropical and sub- resources, humans have a deep rooted tradition of tropical landscapes. Though the reported species venerating nature which is extensively observed are clustered around a few widely distributed across continents (Verschuuren 2010). The tradition families, 71% of them are uniquely represented from has attracted attention of researchers and policy- any single biogeographic region. The use of multiple makers for its impact on local ecological and socio- species in treating an ailment, high use value of the economic dynamics. Ethnomedicine that emanated popular plants, and cross-community similarity in from this tradition, deals health issues with nature- disease treatment reflects rich community wisdom to derived resources.
    [Show full text]
  • Medicinal Plants Research
    V O L U M E -III Glimpses of CCRAS Contributions (50 Glorious Years) MEDICINAL PLANTS RESEARCH CENTRAL COUNCIL FOR RESEARCH IN AYURVEDIC SCIENCES Ministry of AYUSH, Government of India New Delhi Illllllllllllllllllllllllllllllllllllllllllllllllllllllllllllllllllllllllllllllllllllllllllllllllllllllllllllllllllllllllllllllllllllllllllllllll Glimpses of CCRAS contributions (50 Glorious years) VOLUME-III MEDICINAL PLANTS RESEARCH CENTRAL COUNCIL FOR RESEARCH IN AYURVEDIC SCIENCES Ministry of AYUSH, Government of India New Delhi MiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiiM Illllllllllllllllllllllllllllllllllllllllllllllllllllllllllllllllllllllllllllllllllllllllllllllllllllllllllllllllllllllllllllllllllllllllllllllll © Central Council for Research in Ayurvedic Sciences Ministry of AYUSH, Government of India, New Delhi - 110058 First Edition - 2018 Publisher: Central Council for Research in Ayurvedic Sciences, Ministry of AYUSH, Government of India, New Delhi, J. L. N. B. C. A. H. Anusandhan Bhavan, 61-65, Institutional Area, Opp. D-Block, Janakpuri, New Delhi - 110 058, E-mail: [email protected], Website : www.ccras.nic.in ISBN : 978-93-83864-27-0 Disclaimer: All possible efforts have been made to ensure the correctness of the contents. However Central Council for Research in Ayurvedic Sciences, Ministry of AYUSH, shall not be accountable for any inadvertent error in the content. Corrective measures shall be taken up once such errors are brought
    [Show full text]
  • Nephroprotective and Nephrocurative Activity of Alangium Salvifolium Against Gentamicin Induced Nephrotoxicity in Albino Rats
    Karra Geetha et al. / Journal of Pharmacy Research 2014,8(4),576-583 Research Article Available online through ISSN: 0974-6943 http://jprsolutions.info Nephroprotective and nephrocurative activity of Alangium salvifolium against Gentamicin induced nephrotoxicity in albino rats Karra Geetha*1, Nadenla Ramarao 2 1CMR College of Pharmacy 1, Kandlakoya, Medchal, Hyderabad, Andhra Pradesh, India 2Chalapathi Institute of Pharmaceutical Sciences 2, Lam, Guntur, Andhra Pradesh, India Received on:09-03-2014; Revised on: 26-03-2014; Accepted on:11-04-2014 ABSTRACT Objective:To study the nephroprotective, nephrocurative effect of Alangium salvifolium ethanolic bark extract in gentamicin induced nephrotoxicity. Materials and methods: Nephrotoxicity was induced in wistar male rats by intraperitoneal administration of gentamicin at 40mg/kgb.wt /day for 21 days. Alangium salvifolium was selected to check the effect by using ethanolic bark extract with different doses (250,500,750 mg/kg body weight respectively), was given by oral route. Serum parameters (serum creatinine, serum urea,serum proteins, and blood urea nitrogen (BUN)), urine parameters (urine creatinine and urine volume) and other parameters like body weight, in vivo antioxi- dants catalase, reduced glutathione (GSH) and Lipid peroxidase level were determined on 22nd day in wistar male rats .Histopathological study of kidney was studied. Results: The three doses of the extracts produced significant nephroprotective, nephrocurative activities with increased doses. The increased actions of nephroprotective, nephrocurative activity in gentamicin induced nephrotoxicity models as evident by decrease in serum creatinine, serum urea,serum proteins, urine creatinine, BUN levels and lipid peroxidation (MDA).The increased glutathione (GSH), catalase (CAT) activities when compared to gentamicin control group which was further confirmed by histopathological study.
    [Show full text]
  • Phytochemical Screening of Alangium Salviifolium (L.F.) Wangerin Showing Antifungal Properties Against Alternaria Spp
    Plantae Scientia – An International Research Journal in Botany Publishing Bimonthly Open Access Journal Plantae Scientia : Volume 02, Issue 01, May 2019 RESEARCH ARTICLE Phytochemical Screening of Alangium salviifolium (L.f.) Wangerin Showing Antifungal Properties against Alternaria spp. 1Aphajal M., 2Beg M. Jaish 1,2Department of Botany, Shibli National P.G. College Azamgarh -276001 Uttar Pradesh (India) Corresponding Author: [email protected] Mobile: +919889453252 Manuscript Details ABSTRACT Manuscript Submitted : 10/04/2019 The antifungal properties shown by different higher plant Manuscript Revised : 12/04/2019 extracts are due to the presence of phytochemicals. The activities Manuscript Accepted : 15/04/2019 of Alangium salviifolium root in controlling two fungal species that Manuscript Published : 15/05/2019 belong to Alternaria spp- Alternaria brassicae and A. brassicicola, the causal organisms of leaf blight of crucifers were evaluated in vitro Available On assay. The aqueous extracts of different parts of tested plant such as bark, stem, root, leaf and flower were screened against test https://plantaescientia.website/ojs fungi. Among them, the results of the study revealed that the aqueous extracts of A. salviifolium root showed the inhibition of Cite This Article As mycelial growth against test fungi completely (100%). The M. Aphajal & Beg M. Jaish (2019). phytochemical analysis of active plant has revealed that the Phytochemical Screening of Alangium presence of some chemical compounds as alkaloids, terpenoids, salviifolium (L. f.) Wangerin showing phenol/tannins, saponins, flavonoids and glycosides in both antifungal properties against Alternaria spp., aqueous and ethanol extracts is likely to be responsible for the Pla. Sci. 2019; Vol. 02 Iss. 01: 01-04.
    [Show full text]
  • A Review on a Few Medicinal Plants Possessing Anticancer Activity Against Human Breast Cancer
    International Journal of PharmTech Research CODEN (USA): IJPRIF, ISSN: 0974-4304 Vol.9, No.3, pp 333-365, 2016 A Review on a few medicinal plants possessing anticancer activity against human breast cancer Jaikumar B, Jasmine R* PG Research Department of Biotechnology, Bishop Heber College, Trichy-17, India Abstract: Breast Cancer is known to be the second most common cause of death. So there has been intense research on various plant resources to develop novel anticancer agents against breast cancer.Herbal medicine is one of the most commonly used complementary and alternative therapies (CAM) by people with cancer. Some studies have shown that as many as 6 out of every 10 people with cancer (60%) use herbal remedies alongside conventional cancer treatments. There are many different types of herbal medicines and some of them overlap with foods. Commonly used plants include Echinacea, St John’s Wort, green tea and ginger. From the past several years, medicinal plants have been proved to be an important natural source for cancer therapy with fewer side effects. There are many natural cytotoxic drugs available, which needs further improvement and development of new drugs. An attempt has been made to review some medicinal plants used for the prevention and treatment of cancer. This article considers a few medicinal plants used anticancer activity against breast cancer cell line(MCF- 7). It will be helpful to explore the medicinal value of plants and for new drug discovery from them for the researchers and scientists around the globe. Keywords: Medicinal plants, Anticancer, MTT assay, MCF-7 cells. Introduction Cancer is a general term applied of series of malignant diseases that may affect different parts of body.
    [Show full text]
  • 2320-5407 Int. J. Adv. Res. 7(11), 395-403 RESEARCH ARTICLE
    ISSN: 2320-5407 Int. J. Adv. Res. 7(11), 395-403 Journal Homepage: - www.journalijar.com Article DOI: 10.21474/IJAR01/10022 DOI URL: http://dx.doi.org/10.21474/IJAR01/10022 RESEARCH ARTICLE SYSTEMATIC DOCUMENTATION OF TRADITIONAL KNOWLEDGE ON FUNGUS INFECTED ETHNOMEDICINALLY IMPORTANT PLANTS USED BY KANI TRIBES OF KERALA. Dr. Vimalkumar cs. Former research scholar, jawaharlal nehru tropical botanic garden and research institute(jntbgri), palode,thiruvananthapuram, kerala,india. …………………………………………………………………………………………………….... Manuscript Info Abstract ……………………. ……………………………………………………………… Manuscript History Traditional Knowledge associated with biodiversity is a living body of Received: 08 September 2019 functional knowledge system and the same is getting eroded rapidly Final Accepted: 10 October 2019 because of the changing lifestyles of the people. The systematic Published: November 2019 documentation of traditional knowledge related to ethnobotanically important plants deserves utmost importance, and it appears this is Key words:- Traditional Knowledge, systematic particularly true with fungus infected plants. Based on the documentation, ethnomedicinal plants, aforementioned issue, the major lines of work under taken in this fungus, Kani tribes. investigation were a) Systematically Documented Traditional Knowledge related to fungus infected ethnobotanically important plants used by the Kani Tribes of Thiruvananthapuram, Kerala, India b) Data accrued through the documentation were subjected to analysis for scientific validation. The study resulted
    [Show full text]
  • Alangium Salvifolium) - an Ayurvedic Herb
    WORLD JOURNAL OF PHARMACY AND PHARMACEUTICAL SCIENCES Phulwaria et al. World Journal of Pharmacy and Pharmaceutical Sciences SJIF Impact Factor 7.421 Volume 8, Issue 3, 271-279 Review Article ISSN 2278 – 4357 ANKOL (ALANGIUM SALVIFOLIUM) - AN AYURVEDIC HERB Dr. Renuka Phulwaria*, Dr Kamini Kaushal, Dr. Ashwini Kumar Sharma, Dr. Rajesh Chand Mishra and Dr. Pradeep Soni M.D. Scholar1, Prof. and Hod2, Asso. Prof.3, Asso. Prof.4, Lecturer5 PG Department of Dravyaguna, MMM. Govt. Ayu. College, Udaipur. ABSTRACT Article Received on 05 Jan 2019, In India, medicinal plants are widely used by people as folk remedies Revised on 26 Jan. 2019, Accepted on 17 Feb. 2019 or in different indigenous systems of medicine like Siddha, Unani and DOI: 10.20959/wjpps20193-13201 Ayurveda. They are also used in the pharmaceutical preparations. The plant Alangium salvifolium is a small tree or shrub, native to South *Corresponding Author India. It belongs to the family Alangiaceae. All the parts Root, bark, Dr. Renuka Phulwaria leaves, seeds and fruits possessed significant therapeutic uses. These M.D. Scholar PG compounds belong to the natural products called flavinoids, Department of Dravyaguna, glycosides, alkaloids, saponins. During the last three decades, apart MMM. Govt. Ayu. College, from the chemistry of the alangiium compounds, considerable progress Udaipur. has been achieved regarding the medicinal applications and biological activity of alangium. It is considered as a valuable source of natural products for development of medicines against various diseases. This review gives a view mainly on distribution, phytochemistry, pharmacological activities of Alangium salvifolium plant extracts. KEYWORDS: Alangium, south india, Alangiaceae, Flavinoids, Glycosides, Alkaloids, Plant Extract.
    [Show full text]
  • Synthesis and Pharmacological Screening of Novel 1,5-Benzothiazepines
    Academic Sciences Asian Journal of Pharmaceutical and Clinical Research Vol 4, Suppl 2, 2011 ISSN - 0974-2441 Re search Article ANTI ULCER EFFECT OF ALANGIUM SALVIFOLIUM ETHANOLIC LEAF EXTRACT ON GASTRIC LESION INDUCED BY ETHANOL IN RATS 1 1 1 1 2 SREEKANTH .P , SUDHAKARA .K , GOUSE BASHA .G , MURALI .K , SANJEEVA KUMAR .A* 1 2* P. Rami Reddy Memorial College of Pharmacy, Prakruthi Nagar, Kadapa, A.P , Department of Pharmacognosy & Phytochemistry, Vaagdevi College of Pharmacy, Hanamkonda, A.P., India , E mail: [email protected] Received: 21 August 2011, Revised and Accepted: 28 September 2011 ABSTRACT Herbalism is a traditional medicinal or folk medicine practice based on the use of plants and plant extracts. Alangium salvifolium, belongs to the family of Alanginaceae. Based on the ethno pharmacological literatures, the plant Alangium salvifolium has been selected to prove its anti ulcer property on experimental animal models. The phytoconstituents present in the plant were extracted by using different solvents of increasing polarity like n-hexane, chloroform, ethyl acetate, acetone, ethanol and water. The phytoconstituents were identified by various chemical tests which showed the presence of various phytoconstituents. The ethanolic extract of leaves of Alangium salvifolium was selected for the pharmacological screening and evaluated using mice for its toxicity. The LD50 was calculated by using Karber’s method. The ED50 value was found to be 150 mg/kg body weight. By performing anti ulcer activity on male Wistar rats and screened pharmacologically for the anti ulcer activity. From our findings it can be concluded that the ethanolic extract of Alangium salvifolium has a significant anti ulcer activity at 400mg/kg and 800mg/kg dose.
    [Show full text]
  • Osteoprotective Effect of Few Indian Herbs
    Annals of SBV herpes simplex virus 1 (HSV-1) and herpes simplex radioactive elements, studies found that these elements virus 2 (HSV-2). By blocking the binding sites used are usually not released into our food or bodies. Powdered by HSV-1 and HSV-2 for cell attachment, sulphated kelp(s), algin, even sodium alginate, are effectively used to polysaccharides inhibit the replication of these viruses. remove radioactive and heavy metals from the body. The The sulphated polysaccharides in sea vegetables also metabolic process is slow and deliberate. OSTEOPROTECTIVE EFFECT OF FEW INDIAN HERBS: AN UPDATE have important anticoagulant and anti-thrombotic properties that provide significant cardiovascular While sea vegetables contain measurable amounts of Veni Subramanyam, Scientist 1 7 benefits . Sea vegetables are known to remove heavy polyphenols like carotenoids and flavonoids, they also Srinivasan Narasimhan, Professor 2 metals and radioactive pollutants from the body. contain other phyto-nutrient antioxidants that have been Scientists at McGill University in Canada showed shown to possess antioxidant properties11. Coupled with Central Inter-Disciplinary Research Facility, that sodium alginate removes the radioactive element measurable amounts of antioxidant vitamins (like vitamins strontium, along with heavy metals such as cadmium C and E) and antioxidant minerals (like manganese and zinc), 1 Sri Balaji Vidyapeeth, Mahatma Gandhi Medical College and Research Institute Campus and lead8. sea vegetables are expected to reduce the risk of oxidative Pillaiyarkuppam, Puducherry - 607403, India stress and many types of cardiovascular problems that are Sea vegetables may play a role in lowering risk of estrogen- associated with poor antioxidant intake. 2 Faculty of Allied Health Sciences related cancers, including breast cancer.
    [Show full text]
  • Bactrocera Dorsalis
    EPPO Datasheet: Bactrocera dorsalis Last updated: 2021-04-28 IDENTITY Preferred name: Bactrocera dorsalis Authority: (Hendel) Taxonomic position: Animalia: Arthropoda: Hexapoda: Insecta: Diptera: Tephritidae Other scientific names: Bactrocera invadens Drew, Tsuruta & White, Bactrocera papayae Drew & Hancock, Bactrocera philippinensis Drew & Hancock, Chaetodacus dorsalis (Hendel), Chaetodacus ferrugineus dorsalis (Hendel), Chaetodacus ferrugineus okinawanus Shiraki, Chaetodacus ferrugineus (Fabricius), Dacus dorsalis Hendel, Dacus ferrugineus dorsalis more photos... Hendel, Dacus ferrugineus okinawanus Shiraki, Dacus ferrugineus Fabricius, Strumeta dorsalis (Hendel) Common names: oriental fruit fly view more common names online... EPPO Categorization: A1 list view more categorizations online... EU Categorization: A1 Quarantine pest (Annex II A) EPPO Code: DACUDO Notes on taxonomy and nomenclature B. dorsalis forms part of a species complex, within which over 50 species have been described in Asia. Many earlier records of B. dorsalis from Southern India, Indonesia, Malaysia, the Philippines and Sri Lanka are based on misidentifications of what are now (Drew & Hancock, 1994) known to be other species. However, some of these taxa previously described as distinct taxa, i.e. B. invadens, B. papayae, and B. philippinensis are considered as being synonymous (see Schutze et al., 2014). Part of the literature prior to 2015 will have been published under the junior names in particular with reference to studies in Africa under B. invadens. Some researchers (Drew & Romig, 2013; 2016), however, still consider B. papaya and B. invadens to be valid species, different from B. dorsalis. HOSTS B. dorsalis is one of the most polyphagous fruit fly species, recorded from close to 450 different hosts worldwide, belonging to 80 plant families. In addition, it is associated with a large number of other plant taxa for which the host status is not certain.
    [Show full text]