Pigmentary Potential of Various Inland Water Microalgae and Their Applications
Total Page:16
File Type:pdf, Size:1020Kb
Load more
Recommended publications
-
View Article
Cronicon OPEN ACCESS EC Microbiology Review Article Spirulina Rising: Microalgae, Phyconutrients, and Oxidative Stress Mark F McCarty1 and Nicholas A Kerna2,3* 1Catalytic Longevity, USA 2SMC-Medical Research, Thailand 3First InterHealth Group, Thailand *Corresponding Author: Nicholas A Kerna, (mailing address) POB47 Phatphong, Suriwongse Road, Bangrak, Bangkok, Thailand 10500. Contact: [email protected] Received: August 22, 2019; Pubished: June 30, 2021 DOI: 10.31080/ecmi.2021.17.01135 Abstract Oxidative stress provokes the development of many common diseases and contributes to the aging process. Also, oxidative stress is a critical factor in common vascular disorders and type 2 diabetes. It plays a role in neurodegenerative disorders, such as Alzheimer’s disease, Parkinson’s disease, amytrophic lateral sclerosis, multiple sclerosis, and cancer. Oxidative stress contributes to the healthy regulation of cell function. However, excessive oxidative stress results in pathological processes. Antioxidant vitamins have a limited from oxidative stress, and inhibits NOX. PhyCB, a component of the microalgae Spirulina, shares a similar structure with biliverdin, influence on oxidative stress as most oxidative stress results from the cellular production of superoxide. Bilirubin protects cells a biosynthetic precursor of bilirubin. Thus, the oral administration of PhyCB, phycocyanin, or whole Spirulina shows promise for preventing and or treating human disorders that have resulted from excessive oxidative stress. Keywords: Microalgae; Oxidative Stress; Phycocyanobilin; Phyconutrients; Singlet Oxygen; Spirulina; Superoxide Abbreviations DHA: Docosahexaenoic Acid; HO-1: Heme Oxygenase-1; O2: Oxygen; PhyCB: Phycocyanobilin Introduction To understand how phyconutrients, found abundantly in microalgae, can provide preventive and therapeutic effects, it is fundamental to understand how oxidative stress triggers or contributes to the development of many common diseases—and how microalgae, such as Spirulina can help inhibit oxidative stress in the human body. -
Pulegone [89-82-7]
Integrated Laboratory Systems Pulegone [89-82-7] and One Of Its Metabolites Menthofuran [494-90-6] Review of Toxicological Literature Prepared for Errol Zeiger, Ph.D. National Institute of Environmental Health Sciences P.O. Box 12233 Research Triangle Park, North Carolina 27709 Contract No. N01-ES-65402 Submitted by Raymond Tice, Ph.D. Integrated Laboratory Systems P.O. Box 13501 Research Triangle Park, North Carolina 27709 January 1998 EXECUTIVE SUMMARY The nomination of pulegone and menthofuran for testing is based on the potential for human exposure and the absence of carcinogenicity data. Pulegone and menthofuran are available from suppliers of laboratory test chemicals while pennyroyal oil with pulegone as a major constituent is commonly available in health food stores. Pulegone can be synthetically produced but no data were found concerning the synthetic production process; pulegone can also be produced by shoot cultures of Mentha piperita grown in fermenters. No data were found on production or import volumes. Pulegone is a major constituent of several essential oils (e.g., peppermint, pennyroyal) used for flavoring foods and drinks. Pennyroyal oil, which has been reported to contain 75-85% pulegone, has also been used as a fragrance agent and as an herbal medicine to induce menstruation and abortion. A number of plant species contain pulegone and menthofuran, including numerous species of mints such as peppermint and spearmint, the pennyroyals, and mountain mints. Menthofuran is present in peppermint and in M. aquatica and its hybrids. Exposure to pulegone and menthofuran is primarily through ingestion of food products (e.g., frozen dairy dessert, candy, baked goods, gelatins, and puddings) and of alcoholic and nonalcoholic beverages flavored with spearmint oil, peppermint oil, or synthetic pulegone. -
Myoglobin with Modified Tetrapyrrole Chromophores: Binding Specificity and Photochemistry ⁎ Stephanie Pröll A, Brigitte Wilhelm A, Bruno Robert B, Hugo Scheer A
View metadata, citation and similar papers at core.ac.uk brought to you by CORE provided by Elsevier - Publisher Connector Biochimica et Biophysica Acta 1757 (2006) 750–763 www.elsevier.com/locate/bbabio Myoglobin with modified tetrapyrrole chromophores: Binding specificity and photochemistry ⁎ Stephanie Pröll a, Brigitte Wilhelm a, Bruno Robert b, Hugo Scheer a, a Department Biologie I-Botanik, Universität München, Menzingerstr, 67, 80638 München, Germany b Sections de Biophysique des Protéines et des Membranes, DBCM/CEA et URA CNRS 2096, C.E. Saclay, 91191 Gif (Yvette), France Received 2 August 2005; received in revised form 2 March 2006; accepted 28 March 2006 Available online 12 May 2006 Abstract Complexes were prepared of horse heart myoglobin with derivatives of (bacterio)chlorophylls and the linear tetrapyrrole, phycocyanobilin. Structural factors important for binding are (i) the presence of a central metal with open ligation site, which even induces binding of phycocyanobilin, and (ii) the absence of the hydrophobic esterifying alcohol, phytol. Binding is further modulated by the stereochemistry at the isocyclic ring. The binding pocket can act as a reaction chamber: with enolizable substrates, apo-myoglobin acts as a 132-epimerase converting, e.g., Zn-pheophorbide a' (132S) to a (132R). Light-induced reduction and oxidation of the bound pigments are accelerated as compared to solution. Some flexibility of the myoglobin is required for these reactions to occur; a nucleophile is required near the chromophores for photoreduction (Krasnovskii reaction), and oxygen for photooxidation. Oxidation of the bacteriochlorin in the complex and in aqueous solution continues in the dark. © 2006 Elsevier B.V. -
Antiradical and Antibacterial Activity of Essential Oils from the Lamiaceae Family Plants in Connection with Their Composition and Optical Activity of Components
International Journal of Secondary Metabolite 2018, Vol. 5, No. 2, 109–122 DOI: 10.21448/ijsm.408165 Published at http://www.ijate.net http://dergipark.gov.tr/ijsm Research Article Antiradical and Antibacterial Activity of Essential Oils from the Lamiaceae Family Plants in Connection with their Composition and Optical Activity of Components Hanna G. Shutava 1, Tatsiana G. Shutava 2, Natalya A. Kavalenka3, Halina N. Supichenka3 1 Central Botanical Garden, National Academy of Sciences of Belarus, Minsk, Belarus 2 Institute of Chemistry of New Materials, National Academy of Sciences of Belarus, Minsk, Belarus 3 Belarusian State Technological University, Minsk, Belarus Abstract: Antiradical activity of essential oils of korean mint (Agastache rugosa ARTICLE HISTORY (Fisch. et Mey)), blue giant hyssop (Agastache foeniculum (Pursh) Kuntze), hyssop Received: 12 January 2018 (Hyssopus officinalis L.), lavander (Lavandula angustifolia L.), peppermint (Mentha piperita L.), lemon mint (Mentha piperita var. citrata (Ehrh.) Briq), Revised: 11 March 2018 monarda (Monarda fistulosa L.), oregano (Origanum vulgare L.), common sage Accepted: 20 March 2018 (Salvia officinalis L.), clary (Salvia sclarea L.), and winter savory (Satureja montana L.) cultivated in the Central Botanical Garden of NAS of Belarus was KEYWORDS investigated in the reaction with the cation-radicals of 2,2-azino-bis(3- ethylbenzothiazoline-6-sulphonic acid) (ABTS+). The most pronounced Oil composition; antiradical activity was observed for the essential oils with a high content of Antiradical activity, phenolic compounds: winter savory and monarda. Antiradical properties of the Antibacterial activity, essential oils and individual phenolic and terpene compounds (eugenol, carvacrol, Enantiomer, thymol, citral, (+)-pulegone) in the reaction with ABTS+ significantly differ in Lamiaceae aqueous solutions and ethanol-water mixtures. -
Quelques Aspects Problematiques Dans La Transcription Des Toponymes Tunisiens
QUELQUES ASPECTS PROBLEMATIQUES DANS LA TRANSCRIPTION DES TOPONYMES TUNISIENS Mohsen DHIEB Professeur de géographie (cartographie) Laboratoire SYFACTE FLSH de Sfax TUNISIE [email protected] Introduction Quelle que soit le pays ou la langue d’usage, la transcription toponymique des noms de lieux géographiques sur un atlas ou un autre document cartographique en particulier ou tout autre document d’une façon générale pose problème notamment dans des pays où il n’y a pas de tradition ou de « politique » toponymique. Il en est de même pour les contrées « ouvertes » à l’extérieur et par conséquent ayant subi ou subissant encore les influences linguistiques étrangères ou alors dans des régions caractérisées par la complexité de leur situation linguistique. C’est particulièrement le cas de la Tunisie, pays méditerranéen bien « ancré » dans l’histoire, mais aussi bien ouvert à l’étranger et subissant les soubresauts de la mondialisation, et manquant par ailleurs cruellement de politique toponymique. Tout ceci malgré l’intérêt que certains acteurs aux profils différents y prêtent depuis peu, intérêt matérialisé, entre autres manifestations scientifiques, par l’organisation de deux rencontres scientifiques par la Commission du GENUING en 2005 et d’une autre août 2008 à Tunis, lors du 35ème Congrès de l’UGI. Aussi, il s’agit dans le cadre de cette présentation générale de la situation de la transcription toponymique en Tunisie, dans un premier temps, de dresser l’état des lieux, de mettre en valeur les principales difficultés rencontrées en manipulant les noms géographiques dans leurs différentes transcriptions dans un second temps. En troisième lieu, il s’agit de proposer à l’officialisation, une liste-type de toponymes (exonymes et endonymes) que l’on est en droit d’avoir par exemple sur une carte générale de Tunisie à moyenne échelle. -
S.No Governorate Cities 1 L'ariana Ariana 2 L'ariana Ettadhamen-Mnihla 3 L'ariana Kalâat El-Andalous 4 L'ariana Raoued 5 L'aria
S.No Governorate Cities 1 l'Ariana Ariana 2 l'Ariana Ettadhamen-Mnihla 3 l'Ariana Kalâat el-Andalous 4 l'Ariana Raoued 5 l'Ariana Sidi Thabet 6 l'Ariana La Soukra 7 Béja Béja 8 Béja El Maâgoula 9 Béja Goubellat 10 Béja Medjez el-Bab 11 Béja Nefza 12 Béja Téboursouk 13 Béja Testour 14 Béja Zahret Mediou 15 Ben Arous Ben Arous 16 Ben Arous Bou Mhel el-Bassatine 17 Ben Arous El Mourouj 18 Ben Arous Ezzahra 19 Ben Arous Hammam Chott 20 Ben Arous Hammam Lif 21 Ben Arous Khalidia 22 Ben Arous Mégrine 23 Ben Arous Mohamedia-Fouchana 24 Ben Arous Mornag 25 Ben Arous Radès 26 Bizerte Aousja 27 Bizerte Bizerte 28 Bizerte El Alia 29 Bizerte Ghar El Melh 30 Bizerte Mateur 31 Bizerte Menzel Bourguiba 32 Bizerte Menzel Jemil 33 Bizerte Menzel Abderrahmane 34 Bizerte Metline 35 Bizerte Raf Raf 36 Bizerte Ras Jebel 37 Bizerte Sejenane 38 Bizerte Tinja 39 Bizerte Saounin 40 Bizerte Cap Zebib 41 Bizerte Beni Ata 42 Gabès Chenini Nahal 43 Gabès El Hamma 44 Gabès Gabès 45 Gabès Ghannouch 46 Gabès Mareth www.downloadexcelfiles.com 47 Gabès Matmata 48 Gabès Métouia 49 Gabès Nouvelle Matmata 50 Gabès Oudhref 51 Gabès Zarat 52 Gafsa El Guettar 53 Gafsa El Ksar 54 Gafsa Gafsa 55 Gafsa Mdhila 56 Gafsa Métlaoui 57 Gafsa Moularès 58 Gafsa Redeyef 59 Gafsa Sened 60 Jendouba Aïn Draham 61 Jendouba Beni M'Tir 62 Jendouba Bou Salem 63 Jendouba Fernana 64 Jendouba Ghardimaou 65 Jendouba Jendouba 66 Jendouba Oued Melliz 67 Jendouba Tabarka 68 Kairouan Aïn Djeloula 69 Kairouan Alaâ 70 Kairouan Bou Hajla 71 Kairouan Chebika 72 Kairouan Echrarda 73 Kairouan Oueslatia 74 Kairouan -
MCKENNA-THESIS-2016.Pdf
IDENTIFICATION AND CHARACTERIZATION OF MINT LACTONES: TRACE-LEVEL ODOR-IMPORTANT AROMA COMPOUNDS IN PEPPERMINT OIL BY SAMANTHA GRACE MCKENNA THESIS Submitted in partial fulfillment of the requirements for the degree of Master of Science in Food Science and Human Nutrition with a concentration in Food Science in the Graduate College of the University of Illinois at Urbana-Champaign, 2016 Urbana, Illinois Master’s Committee: Professor Keith R. Cadwallader, Chair and Adviser Professor Nicki J. Engeseth Professor Shelly J. Smith ABSTRACT Mentha piperita L., commonly known as peppermint, is an essential oil bearing plant that was introduced to the United States in the early-19th century. By 1900 peppermint cultivation and oil production had reached the Pacific Northwest where the majority of peppermint oil in the United States is produced today. In 2015 the United States produced 5.9 million pounds of peppermint oil which is used in a wide variety of food and flavor applications including chewing gum, oral hygiene products, pharmaceuticals, confectionary, and liquor among others. Trace odorants are crucial to the flavor profile of well-balanced peppermint oil. Certain lactones have been identified in peppermint oils in trace levels that contribute important sweet, coconut, coumarin-like aroma characteristics to the oils. Among these lactones, collectively known as “mint lactones”, (−)-mintlactone and (+)-isomintlactone are the most well characterized, although numerous others remain unidentified. Four peppermint oils were analyzed by gas chromatography-olfactometry (GCO) and gas chromatography-mass spectrometry (GC-MS) to identify the odor-active lactones. Since lactones are present at trace levels, a silica gel fractionation method was developed to isolate and concentrate the lactones from peppermint oil prior to GC analysis. -
Phototrophic Pigment Production with Microalgae
Phototrophic pigment production with microalgae Kim J. M. Mulders Thesis committee Promotor Prof. Dr R.H. Wijffels Professor of Bioprocess Engineering Wageningen University Co-promotors Dr D.E. Martens Assistant professor, Bioprocess Engineering Group Wageningen University Dr P.P. Lamers Assistant professor, Bioprocess Engineering Group Wageningen University Other members Prof. Dr H. van Amerongen, Wageningen University Prof. Dr M.J.E.C. van der Maarel, University of Groningen Prof. Dr C. Vilchez Lobato, University of Huelva, Spain Dr S. Verseck, BASF Personal Care and Nutrition GmbH, Düsseldorf, Germany This research was conducted under the auspices of the Graduate School VLAG (Advanced studies in Food Technology, Agrobiotechnology, Nutrition and Health Sciences). Phototrophic pigment production with microalgae Kim J. M. Mulders Thesis submitted in fulfilment of the requirement for the degree of doctor at Wageningen University by the authority of the Rector Magnificus Prof. Dr M.J. Kropff, in the presence of the Thesis Committee appointed by the Academic Board to be defended in public on Friday 5 December 2014 at 11 p.m. in the Aula. K. J. M. Mulders Phototrophic pigment production with microalgae, 192 pages. PhD thesis, Wageningen University, Wageningen, NL (2014) With propositions, references and summaries in Dutch and English ISBN 978-94-6257-145-7 Abstract Microalgal pigments are regarded as natural alternatives for food colourants. To facilitate optimization of microalgae-based pigment production, this thesis aimed to obtain key insights in the pigment metabolism of phototrophic microalgae, with the main focus on secondary carotenoids. Different microalgal groups each possess their own set of primary pigments. Besides, a selected group of green algae (Chlorophytes) accumulate secondary pigments (secondary carotenoids) when exposed to oversaturating light conditions. -
Scalable Production of Biliverdin Ixα by Escherichia Coli Dong Chen1, Jason D Brown1, Yukie Kawasaki2, Jerry Bommer3 and Jon Y Takemoto1,2*
Chen et al. BMC Biotechnology 2012, 12:89 http://www.biomedcentral.com/1472-6750/12/89 RESEARCH ARTICLE Open Access Scalable production of biliverdin IXα by Escherichia coli Dong Chen1, Jason D Brown1, Yukie Kawasaki2, Jerry Bommer3 and Jon Y Takemoto1,2* Abstract Background: Biliverdin IXα is produced when heme undergoes reductive ring cleavage at the α-methene bridge catalyzed by heme oxygenase. It is subsequently reduced by biliverdin reductase to bilirubin IXα which is a potent endogenous antioxidant. Biliverdin IXα, through interaction with biliverdin reductase, also initiates signaling pathways leading to anti-inflammatory responses and suppression of cellular pro-inflammatory events. The use of biliverdin IXα as a cytoprotective therapeutic has been suggested, but its clinical development and use is currently limited by insufficient quantity, uncertain purity, and derivation from mammalian materials. To address these limitations, methods to produce, recover and purify biliverdin IXα from bacterial cultures of Escherichia coli were investigated and developed. Results: Recombinant E. coli strains BL21(HO1) and BL21(mHO1) expressing cyanobacterial heme oxygenase gene ho1 and a sequence modified version (mho1) optimized for E. coli expression, respectively, were constructed and shown to produce biliverdin IXα in batch and fed-batch bioreactor cultures. Strain BL21(mHO1) produced roughly twice the amount of biliverdin IXα than did strain BL21(HO1). Lactose either alone or in combination with glycerol supported consistent biliverdin IXα production by strain BL21(mHO1) (up to an average of 23. 5mg L-1 culture) in fed-batch mode and production by strain BL21 (HO1) in batch-mode was scalable to 100L bioreactor culture volumes. -
MPLS VPN Service
MPLS VPN Service PCCW Global’s MPLS VPN Service provides reliable and secure access to your network from anywhere in the world. This technology-independent solution enables you to handle a multitude of tasks ranging from mission-critical Enterprise Resource Planning (ERP), Customer Relationship Management (CRM), quality videoconferencing and Voice-over-IP (VoIP) to convenient email and web-based applications while addressing traditional network problems relating to speed, scalability, Quality of Service (QoS) management and traffic engineering. MPLS VPN enables routers to tag and forward incoming packets based on their class of service specification and allows you to run voice communications, video, and IT applications separately via a single connection and create faster and smoother pathways by simplifying traffic flow. Independent of other VPNs, your network enjoys a level of security equivalent to that provided by frame relay and ATM. Network diagram Database Customer Portal 24/7 online customer portal CE Router Voice Voice Regional LAN Headquarters Headquarters Data LAN Data LAN Country A LAN Country B PE CE Customer Router Service Portal PE Router Router • Router report IPSec • Traffic report Backup • QoS report PCCW Global • Application report MPLS Core Network Internet IPSec MPLS Gateway Partner Network PE Router CE Remote Router Site Access PE Router Voice CE Voice LAN Router Branch Office CE Data Branch Router Office LAN Country D Data LAN Country C Key benefits to your business n A fully-scalable solution requiring minimal investment -
(R)-(+)-Pulegone, a Chemical Constituent of Essential Oils Damião P
Pharmacological Activity of (R)-(+)-Pulegone, a Chemical Constituent of Essential Oils Damião P. de Sousaa, Franklin F. F. Nóbregab, Maria R. V. de Limab, and Reinaldo N. de Almeidab,* a Department of Physiology, Federal University of Sergipe, CEP 49100–000, Aracaju, Sergipe, Brazil b Laboratório de Tecnologia Farmacêutica, Federal University of Paraíba, Caixa Postal 5009, CEP 58051–970, João Pessoa, Paraíba, Brazil. E-mail: [email protected] * Author for correspondence and reprint requests Z. Naturforsch. 66 c, 353 – 359 (2011); received April 24, 2010/March 10, 2011 (R)-(+)-Pulegone is a monoterpene found in essential oils from plants of the Labiatae family. This compound is a major constituent of Agastache formosanum oil. In this study, the effect of (R)-(+)-pulegone on the central nervous system was evaluated. (R)-(+)-Pule- gone caused a signifi cant decrease in ambulation and an increase in pentobarbital-induced sleeping time in mice, indicating a central depressant effect. (+)-Pulegone also signifi cantly increased the latency of convulsions as assessed by the pentylenetetrazole (PTZ) method. The antinociceptive properties of this monoterpene were studied in chemical and thermal models of nociception. Chemical nociception induced in the fi rst and second phase of the subplantar formalin test was signifi cantly inhibited by (R)-(+)-pulegone and was not blocked by naloxone. Thermal nociception was also signifi cantly inhibited while (R)-(+)-pulegone increased the reaction latency of the mice in the hot plate test. These results suggest that (R)-(+)-pulegone is a psychoactive compound and has the profi le of an analgesic drug. Key words: Essential Oils, Antinociceptive Activity, Analgesic Introduction that they have the complex profi le of psychoac- tive drugs. -
Medically Useful Plant Terpenoids: Biosynthesis, Occurrence, and Mechanism of Action
molecules Review Medically Useful Plant Terpenoids: Biosynthesis, Occurrence, and Mechanism of Action Matthew E. Bergman 1 , Benjamin Davis 1 and Michael A. Phillips 1,2,* 1 Department of Cellular and Systems Biology, University of Toronto, Toronto, ON M5S 3G5, Canada; [email protected] (M.E.B.); [email protected] (B.D.) 2 Department of Biology, University of Toronto–Mississauga, Mississauga, ON L5L 1C6, Canada * Correspondence: [email protected]; Tel.: +1-905-569-4848 Academic Editors: Ewa Swiezewska, Liliana Surmacz and Bernhard Loll Received: 3 October 2019; Accepted: 30 October 2019; Published: 1 November 2019 Abstract: Specialized plant terpenoids have found fortuitous uses in medicine due to their evolutionary and biochemical selection for biological activity in animals. However, these highly functionalized natural products are produced through complex biosynthetic pathways for which we have a complete understanding in only a few cases. Here we review some of the most effective and promising plant terpenoids that are currently used in medicine and medical research and provide updates on their biosynthesis, natural occurrence, and mechanism of action in the body. This includes pharmacologically useful plastidic terpenoids such as p-menthane monoterpenoids, cannabinoids, paclitaxel (taxol®), and ingenol mebutate which are derived from the 2-C-methyl-d-erythritol-4-phosphate (MEP) pathway, as well as cytosolic terpenoids such as thapsigargin and artemisinin produced through the mevalonate (MVA) pathway. We further provide a review of the MEP and MVA precursor pathways which supply the carbon skeletons for the downstream transformations yielding these medically significant natural products. Keywords: isoprenoids; plant natural products; terpenoid biosynthesis; medicinal plants; terpene synthases; cytochrome P450s 1.