DOCSLIB.ORG

ESPEN Guidelines on Definitions and Terminology of Clinical Nutrition

Total Page：16

File Type：pdf, Size：1020Kb

Download full-text PDF Read full-text
ESPEN Guidelines on Definitions and Terminology of Clinical Nutrition Clinical Nutrition 36 (2017) 49e64 Contents lists available at ScienceDirect Clinical Nutrition journal homepage: http://www.elsevier.com/locate/clnu ESPEN Guideline ESPEN guidelines on definitions and terminology of clinical nutrition * T. Cederholm a, , R. Barazzoni b, P. Austin c, y, P. Ballmer d, G. Biolo e, S.C. Bischoff f, C. Compher g, 1, I. Correia h, 1, T. Higashiguchi i, 1, M. Holst j, G.L. Jensen k, 1, A. Malone l, 1, M. Muscaritoli m, I. Nyulasi n, 1, M. Pirlich o, E. Rothenberg p, K. Schindler q, S.M. Schneider r, M.A.E. de van der Schueren s, z, C. Sieber t, L. Valentini u, J.C. Yu v, 1, A. Van Gossum w, P. Singer x a Departments of Geriatric Medicine, Uppsala University Hospital and Public Health and Caring Sciences, Clinical Nutrition and Metabolism, Uppsala University, Uppsala, Sweden b Department of Medical, Surgical and Health Sciences, University of Trieste, Trieste, Italy c Pharmacy Department, Oxford University Hospitals NHS Foundation Trust, United Kingdom d Department of Medicine, Kantonsspital Winterthur, Winterthur, Switzerland e Institute of Clinical Medicine, University of Trieste, Trieste, Italy f Institute of Nutritional Medicine, University of Hohenheim, Stuttgart, Germany g School of Nursing, University of Pennsylvania, Philadelphia, PA, USA h Department of Surgery, Federal University of Minas Gerais, Belo Horizonte, Brazil i Department of Surgery and Palliative Medicine, Fujita Health University, School of Medicine, Toyoake, Japan j Center for Nutrition and Bowel Disease, Department of Gastroenterology, Aalborg University Hospital, Aalborg, Denmark k The Dean's Office and Department of Medicine, The University of Vermont College of Medicine, Burlington, VT, USA l Pharmacy Department, Mount Carmel West Hospital, Columbus, OH, USA m Department of Clinical Medicine, Sapienza University of Rome, Italy n Nutrition and Dietetics, Alfred Health, Melbourne, Australia o Department of Internal Medicine, Elisabeth Protestant Hospital, Berlin, Germany p Department of Food and Meal Science, Kristianstad University, Kristianstad, Sweden q Department of Internal Medicine III, Division of Endocrinology and Metabolism, Medical University Vienna, Vienna, Austria r Department of Gastroenterology and Clinical Nutrition, Archet Hospital, University of Nice Sophia Antipolis, Nice, France s Department of Nutrition and Dietetics, Internal Medicine, VU University Medical Center, Amsterdam, The Netherlands t Institute for Biomedicine of Ageing, Friedrich-Alexander University Erlangen-Nürnberg, Hospital St. John of Lord, Regensburg, Germany u Department of Agriculture and Food Sciences, Section of Dietetics, University of Applied Sciences, Neubrandenburg, Germany v Department of General Surgery, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China w Department of Gastroenterology, Clinic of Intestinal Diseases and Nutritional Support, Hopital Erasme, Free University of Brussels, Brussels, Belgium x Department of Critical Care, Institute for Nutrition Research, Rabin Medical Center, Sackler School of Medicine, Tel Aviv University, Petah Tikva 49100 Israel y Pharmacy Department, University Hospital Southampton NHS Foundation Trust, United Kingdom z Department of Nutrition, Sports and Health, Faculty of Health and Social Studies, HAN University of Applied Sciences, Nijmegen, The Netherlands article info summary Article history: Background: A lack of agreement on definitions and terminology used for nutrition-related concepts and Received 9 September 2016 procedures limits the development of clinical nutrition practice and research. Accepted 9 September 2016 Objective: This initiative aimed to reach a consensus for terminology for core nutritional concepts and procedures. Keywords: Methods: The European Society of Clinical Nutrition and Metabolism (ESPEN) appointed a consensus Terminology group of clinical scientists to perform a modified Delphi process that encompassed e-mail communi- Definition cation, face-to-face meetings, in-group ballots and an electronic ESPEN membership Delphi round. * Corresponding author. Clinical Nutrition and Metabolism, Public Health and Caring Sciences, Uppsala University, Uppsala Science Center, Dag Hammarskjoldsv€ ag€ 14B, 751 85 Uppsala, Sweden. E-mail addresses: [email protected] (T. Cederholm), [email protected] (R. Barazzoni), [email protected] (P. Austin), [email protected] (P. Ballmer), [email protected] (G. Biolo), [email protected] (S.C. Bischoff), [email protected] (C. Compher), [email protected] (I. Correia), [email protected] (T. Higashiguchi), [email protected] (M. Holst), [email protected] (G.L. Jensen), [email protected] (A. Malone), [email protected] (M. Muscaritoli), [email protected] (I. Nyulasi), [email protected] (M. Pirlich), elisabet.rothenberg@ vgregion.se (E. Rothenberg), [email protected] (K. Schindler), [email protected] (S.M. Schneider), [email protected] (M.A.E. de van der Schueren), [email protected] (C. Sieber), [email protected] (L. Valentini), [email protected] (J.C. Yu), [email protected] (A. Van Gossum), pierre. [email protected] (P. Singer). 1 Global co-authors contributing late in the process. http://dx.doi.org/10.1016/j.clnu.2016.09.004 0261-5614/© 2016 European Society for Clinical Nutrition and Metabolism. Published by Elsevier Ltd. All rights reserved. 50 T. Cederholm et al. / Clinical Nutrition 36 (2017) 49e64 Consensus Results: Five key areas related to clinical nutrition were identified: concepts; procedures; organisation; Malnutrition Clinical nutrition delivery; and products. One core concept of clinical nutrition is malnutrition/undernutrition, which in- Medical nutrition cludes disease-related malnutrition (DRM) with (eq. cachexia) and without inflammation, and malnu- trition/undernutrition without disease, e.g. hunger-related malnutrition. Over-nutrition (overweight and obesity) is another core concept. Sarcopenia and frailty were agreed to be separate conditions often associated with malnutrition. Examples of nutritional procedures identified include screening for sub- jects at nutritional risk followed by a complete nutritional assessment. Hospital and care facility catering are the basic organizational forms for providing nutrition. Oral nutritional supplementation is the preferred way of nutrition therapy but if inadequate then other forms of medical nutrition therapy, i.e. enteral tube feeding and parenteral (intravenous) nutrition, becomes the major way of nutrient delivery. Conclusion: An agreement of basic nutritional terminology to be used in clinical practice, research, and the ESPEN guideline developments has been established. This terminology consensus may help to support future global consensus efforts and updates of classification systems such as the International Classification of Disease (ICD). The continuous growth of knowledge in all areas addressed in this statement will provide the foundation for future revisions. © 2016 European Society for Clinical Nutrition and Metabolism. Published by Elsevier Ltd. All rights reserved. 1. Introduction established [2]. The presented Guideline standard operating pro- cedures (SOP) aimed to generate high quality guidelines using a Nutrition plays a pivotal role in life and in medicine. Acute and clear and straight-forward consensus procedure, with one of the chronic diseases in most organ systems have pronounced effects on goals to establish international leadership in creating up-to-date food intake and metabolism with increased catabolism, which lead and suitable-for-implementation guidelines. To provide a termi- to nutrition-related conditions associated with increased morbidity nology basis for the guideline development was one of the reasons and eventually death. At the other end of the spectrum, diet is a for launching this initiative. major determinant of future health, i.e. the absence or post- An international expert group of experienced clinical scientists ponement of disorders like cardio-vascular disease, diabetes, can- was compiled to form the Terminology Consensus Group and to cer and cognitive disease [1]. undertake a modified Delphi process. The consensus group par- In order to handle nutritional challenges during disease, trauma, ticipants, i.e. the authors, were selected to represent various clinical rehabilitation, and elderly care as well as for the nutritional pre- nutrition fields, as well as various professions; dietitians, nurses, vention of disease it is essential to use professional language and nutritionists, pharmacists and physicians from clinical and basic standard terminology that is founded on evidence and widely science. It was agreed within the group to base the process on open accepted in the professional community. However, this is not al- e-mail communications, face-to-face meetings and open and closed ways the case. For example, concepts and terms of nutritional ballots. The purpose was to ensure that communication was disorders in the current International Classifications of Diseases maintained at each milestone (see below) until a consensus was (ICD-10) (http://www.who.int/classifications/icd/en/) may not al- reached among all participants. Thus, the statements are based on ways be consistent with modern understanding or terms consensus rather than on systematic literature searches. commonly used in clinical practice and research.
Load more

Recommended publications
  • Nutrition — Ph.D. 1
    Nutrition — Ph.D. 1 NUTRITION — PH.D. Prerequisites • Master's degree in nutrition preferred; or an M.S. or M.P.H. degree Program director with completion of all prerequisite courses; or a health professional Sujatha Rajaram degree at the master's level or higher (M.D. or equivalent) • Advanced biochemistry (may be taken concurrently with the program) The Doctor of Philosophy (Ph.D.) degree in nutrition prepares students to • Anatomy and physiology, microbiology, general chemistry, and effectively conduct nutrition research as well as apply nutritional science organic chemistry knowledge and appropriate research methods to address public health problems. The program provide's an advanced curriculum in nutrition, • G.P.A. of 3.5 or higher preferred th professional skills, and competencies required to support careers in • GRE or equivalent (above the 40 percentile in each section is teaching and research. This program is uniquely situated in the School favorable) of Public Health at a health sciences university. The program engages in interdisciplinary research, encouraging collaboration across public Individuals who may benefit from the health disciplines and the basic sciences, promoting and building upon its core legacy of vegetarian and plant-based nutrition. Areas of curricular program strength and research emphasis include plant-based diets and the health Individuals seeking careers in: of the individual, populations and the planet, nutritional epidemiology, diet • Academia (teaching and research) and chronic disease-risk reduction, and community nutrition. • Researcher in private industry, governmental agencies, nonprofit Students enrolled in this program are able to concurrently complete organizations, or research institutes coursework and practice experience necessary to sit for the registered • Public health nutritionist dietitian nutritionist (RDN) exam if not already an RDN.
    [Show full text]
  • Symptom Management for Cardiac Anorexia/Cachexia
    Hospice Palliative Care HPC Consultation Services Waterloo Wellington Tip of the Month [email protected] May 2019 Palliative Approach to Care Tips: Symptom Management for Cardiac Anorexia/Cachexia • Focus interventions on treatment of Anorexia symptoms and reduction of psychological and social burden for patient and family. Anorexia is a syndrome characterized by loss of appetite, nausea, early satiety, weakness, fatigue, food aversion, and • Cachexia is not starvation. In cachexia, significant physical and/or psychological symptoms. Causes are complex and can include fatigue, dyspnea, medication side- effects, nausea, depression, anxiety and sodium-restricted diets, which are common to patients with heart failure. catabolism and subsequent weight loss continue to occur, even if caloric intake is Cachexia maintained or increased. Cachexia is a syndrome characterized by severe body weight, fat and muscle loss and increased protein catabolism due to • Educate patient/family about the underlying disease. This occurs in both chronic right-sided heart failure and the advanced stages of heart failure. difference between weight loss related to How is cachexia diagnosed? The patient with cachexia has: cachexia versus diuresis. • >5% non-edematous weight loss in <12 months; or body mass index (BMI) <20kg/m2; and • Artificial nutrition in the context of • 3 out of 5 of the following: fatigue, decreased muscle strength, anorexia, low muscle mass, abnormal biochemistry advanced cachexia is ineffective and will Screening not improve quality of life. • Screen with Edmonton Symptom Assessment System (ESAS-r) for issues with appetite, nausea, fatigue, depression. Assessment Figure 1: Understanding the Effects • of the Cachexia Cycle Obtain a thorough history of nutritional intake, weight loss, and symptoms (nausea, early satiety, dyspnea, poor oral hygiene, dysphagia, malabsorption, bowel habits).
    [Show full text]
  • J. Michael Mcginnis, Md, Ma, Mpp
    J. MICHAEL MCGINNIS, MD, MA, MPP National Academy of Medicine, the National Academies, 500 Fifth Street NW, Washington DC 20001, (202) 334-3963, [email protected] Highlights: Michael McGinnis is a physician and epidemiologist who lives and works in Washington DC. Through his writing, government service, and work in philanthropy, he has been a long-time contributor to national and international field leadership in health, health care, and health policy. He currently serves at the National Academy of Medicine (NAM), where he is the Leonard D. Schaeffer Executive Officer, Senior Scholar, and Executive Director of the NAM’s Leadership Consortium for public and private collaboration on behalf of a continuously learning health system. Previously, he served as founding Director, respectively, of the Robert Wood Johnson Foundation’s (RWJF) Health Group, the World Health Organization’s Office for Health Reconstruction in Bosnia, the federal Office of Research Integrity (interim), and the federal Office of Disease Prevention and Health Promotion. In a tenure unusual for political and policy posts, he held continuous appointment through the Carter, Reagan, Bush and Clinton Administrations at the Department of Health and Human Services, with policy responsibilities for disease prevention and health promotion (1977-1995). Programs and policies conceived and launched at his initiative include the Healthy People process establishing national health goals and objectives (1979-present), the U.S. Preventive Services Task Force (1984-present), the Dietary Guidelines for Americans (with USDA, 1980- present), the multi-level Public Health Functions Steering Group and the Ten Essential Services of Public Health (1994-present), the RWJF Active Living family of programs (2000-present), the RWJF Young Epidemiology Scholars Program (2001-2012), the RWJF Health and Society Scholars Program (2002-2017), and the current Learning Health System initiative of the NAM.
    [Show full text]
  • Aspartame Studies by Dr. Mercola
    Aspartame Studies Health Problem: Brain damage/Cognitive skills disruption/Retardation/Neurochemical changes in the brain/Behavioral and Mood Changes/Problems Reference: http://aspartame.mercola.com/sites/aspartame/studies.aspx 1. Year Published: 1970 Full Reference: Brain Damage in Infant Mice Following Oral Intake of Glutamate, Aspartate, or Cysteine; Nature 1970;227-609-610 Funded By: Washington University Conclusion/Findings: Irreversible degenerative changes and acute neuronal necrosis Hyperlink to Study http://www.nature.com/nature/journal/v227/n5258/pdf/227609b0.pdf 2. Year Published: 2008 Full Reference: Direct and Indirect Cellular Effects of Aspartame on the Brain. European Journal of Clinical Nutrition (2008) 62, 451-462; P. Humphries, E. Pretorius, and H. Naude Funded By: Not known Conclusion/Findings: Excessive aspartame ingestion might cause certain mental disorders, as well as compromised learning and emotional functioning Hyperlink to Study: http://www.newmediaexplorer.org/sepp/aspartamebrain.pdf 3. Year Published: 2007 Full Reference: Life-Span Exposure to Low Doses of Aspartame Beginning During Prenatal Life Increases Cancer Effects in Rats, Morando Soffritti, Fiorella Belpoggi, Eva Tibaldi, Davide Degli Esposti, Michelina Lauriola; Environmental Health Perspectives, 115(9) Sep 2007; 115:1293-1297. doi:10.1289/ehp.10271. Funded By: Not known Conclusion/Findings: Carcinogenicity proven a second time; with effects increased when exposure to aspartame begins during fetal life. Hyperlink to Study: http://ehp03.niehs.nih.gov/article/fetchArticle.action?articleURI=info:doi/10.1289/ehp.10271 4. Year Published: 1984 Full Reference: Effects of Aspartame and Glucose on Rat Brain Amino Acids and Serotonin. Yokogoshi H, Roberst CH, Caballero B, Wurtman RJ. American Journal of clinical Nutrition.
    [Show full text]
  • The Practice of Epidemiology
    The Practice of Epidemiology A Meta-Regression Method for Studying Etiologic Heterogeneity across Disease Subtypes Classified by Multiple Biomarkers Molin Wang, Aya Kuchiba, Shuji Ogino Correspondence to Molin Wang, Departments of Biostatistics and Epidemiology, Harvard T.H. Chan School of Public Health, and Channing Division of Network Medicine, Brigham and Women’s Hospital, Harvard Medical School, 677 Huntington Ave., Boston, Massachusetts (email: [email protected]) Abbreviations: CIMP, CpG island methylator phenotype; HPFS, Health Professionals Follow-up Study; MPE, molecular pathological epidemiology; MSI, microsatellite instability; MSS, microsatellite stable; NHS, the Nurses’ Health Study; OR, odds ratio; RR, relative risk; RRR, ratio of relative risk. We use standardized official symbol BRAF, which is described at www.genenames.org. Word count main abstract: 200 Word count text: 3615 N.Figures: 0 N.Tables: 2 Appendices: 0 1 Abstract In interdisciplinary biomedical, epidemiological, and population research, it is increasingly necessary to consider pathogenesis and inherent heterogeneity of any given health condition and outcome. As the unique disease principle implies, no single biomarker can perfectly define disease subtypes. The complex nature of molecular pathology and biology necessitates biostatistical methodologies to simultaneously analyze multiple biomarkers and subtypes. To analyze and test for heterogeneity hypothesis across subtypes defined by multiple categorical and/or ordinal markers, the authors developed a meta-regression method that can utilize existing statistical software for mixed model analysis. This method can be used to assess whether the exposure- subtype associations are different across subtypes defined by one marker while controlling for other markers, and to evaluate whether the difference in exposure- subtype association across subtypes defined by one marker depends on any other markers.
    [Show full text]
  • Cachexia: the Physical and Psychosocial Impact
    Cachexia: The physical and psychosocial impact Caroline Quilty RD, MSc Specialist Palliative Care Dietitian/Therapies Services Manager Aims What is cachexia & why should we be concerned about it? Consider the impact of anorexia in cachexia What are the physical and psychosocial effects of cachexia Identify our role in the management of patients with cachexia What is Cachexia? Cachexia in any disease refers to a state of severely and pathologically low weight, due principally to the loss of mass of tissues other than fat • a serious and under-recognised consequence of cancer (von Haeling and Ankers 2010) • Cachexia is a hallmark of certain diseases including cancer and COPD (Wagner 2008) What is cachexia? “a multifactorial syndrome characterised by an ongoing loss of skeletal muscle mass (with or without loss of fat mass) that cannot be fully reversed by conventional nutrition support, and progressive functional impairment. The pathophysiology is characterised by a negative protein and energy balance driven by a variable combination of reduced food intake and abnormal metabolism.” Fearon et al 2011 Prevalence Prevalence of cancer cachexia is high, ranging from 50-80% in advanced cancer (von Haeling and Ankers 2014) 20 – 40% of people with COPD have cachexia (von Haeling 2010) What does cachexia look like? The word cachexia has Greek roots, “kakos” meaning bad and “hexus” meaning habit, appearance, condition. Cachexia has been known for centuries (von Haehling 2010) and was described by Hippocrates “…the shoulders, clavicles, chest and thighs melt away” (Katz and Katz 1962). Some terms: Term Definition Ref Anorexia loss of appetite and diminished intake. Poole and Prevalent in cachexia Frogatt 2002 Malnutrition A state of nutrition in which a deficiency of energy, Elia 2003 protein and/or other nutrients causes measurable adverse effects on tissue/body form, composition, function or clinical outcome.
    [Show full text]
  • High-Dose Vitamin C in Advanced-Stage Cancer Patients
    nutrients Review High-Dose Vitamin C in Advanced-Stage Cancer Patients Anna Zasowska-Nowak 1,* , Piotr Jan Nowak 2 and Aleksandra Ciałkowska-Rysz 1 1 Department of Palliative Medicine, Chair of Oncology, Medical University of Lodz, Ul. Zeromskiego 113, 90-549 Lodz, Poland; [email protected] 2 Department of Nephrology, Hypertension and Kidney Transplantation, Medical University of Lodz, Ul. Pomorska 251, 92-213 Lodz, Poland; [email protected] * Correspondence: [email protected] Abstract: High-dose intravenously administered vitamin C (IVC) is widely used in cancer patients by complementary and alternative medicine practitioners. The most frequent indications for IVC therapy result from the belief in its effectiveness as a potent anti-cancer agent which additionally enhances chemosensitivity of cancer cells and reduces chemotherapy-related toxicities and fatigue intensity. In this narrative review, we decided to deal with this issue, trying to answer the question whether there is any scientific evidence supporting the rationale for application of high-dose IVC therapy in advanced-stage cancer patients. Although results obtained from preclinical studies demon- strated that millimolar ascorbate plasma concentrations achievable only after IVC administration were cytotoxic to fast-growing malignant cells and inhibited tumor growth as well as prolonged the survival of laboratory animals, such positive effects were not found in human studies with advanced-stage cancer patients. We also have not found the rationale for the use of IVC to increase the effectiveness of chemotherapy and to reduce the chemotherapy-induced toxicity in the above mentioned group. Nevertheless, in palliative care, high-dose IVC might be considered as a ther- apy improving the quality of life and reducing cancer-related symptoms, such as fatigue and bone Citation: Zasowska-Nowak, A.; pain.
    [Show full text]
  • Encouraging Healthy Lifestyle Practices to Protect Health from Environmental Pollution
    Encouraging Healthy Lifestyle Practices to Protect Health from Environmental Pollution Dawn Brewer, PhD, RD, LD July 26, 2019 NIEHS Superfund Research Program (SRP) Purpose: The NIEHS SRP supports research that provides practical, scientific solutions to protect health, the environment and communities. Source: https://tools.niehs.nih.gov/srp/sites/www.cfm University of Kentucky Superfund Research Center (UK-SRC): Nutrition and Superfund Chemical Toxicity Polychlorinated biphenyls (PCBs) Cl Cl Cl Cl Cl Exposure Cardiovascular diseases Diabetes Obesity Cancer Oxidative Suppression of the immune system damage Dysfunction of reproductive and nervous systems Source: Sci Total Environ. 2009 Dec 1; 407(24): 6109-6119 Source: http://www.epa.gov/opptintr/pcb/ Kentucky Contains Hundreds of Hazardous Waste Sites and Contaminated Waterways • 13 National Priority List sites • 248 state superfund sites • 465 sites pending review • Fish consumption advisories for PCBs exist for Kentucky streams and the entire Ohio River that forms the northern border Source: https://www.kyforward.com/wp-content/uploads/2018/11/Kentucky- Waterways-map.jpg Kentucky Experiences Poor Health Outcomes United Health Indicator Kentucky States Ranking Diabetes (%) 12.9 10.5 44 Heart disease (%) 6.2 3.9 49 Cancer deaths (per 100,000 population) 234.9 189.8 50 High blood pressure (%) 39.4 32.2 46 Obesity (%) 34.3 31.3 43 Source: America's Health Rankings analysis of CDC WONDER Online Database, Underlying Cause of Death, Multiple Cause of Death files, United Health Foundation, AmericasHealthRankings.org, Accessed 2019. Kentuckians Face Increased Vulnerability to Environmental Pollution • A growing and convincing body of research (including results from UK-SRC) indicates that nutrition may function as a modulator of vulnerability to environmental insults with nutrition serving to both better or worsen the health impacts associated with exposure to environmental toxins.
    [Show full text]
  • Master of Public Health/Master of Science in Nutrition Dual Degree Proposal (Plan B, Non-Thesis Requiring) Document of December
    Master of Public Health/Master of Science in Nutrition Dual Degree Proposal (Plan B, non-thesis requiring) Document of December 8, 2014; Revised February 2, 2015 This is a dual degree program that is offered jointly by the Departments of Epidemiology and Biostatistics, and Nutrition. The core Master Degree courses include a mixture of those from nutrition, biochemistry and public health. 1. Background and Justification The World Health Organization, (WHO), identifies diet and nutrition as a lifestyle factor critical for maintenance of health and well-being, as well as a factor influencing risk of chronic disease. Cardiovascular disease, diabetes, cancer and obesity are examples of chronic diseases significantly related to diet and nutrition. Obesity is one of the most common conditions and is growing to epidemic proportions. The two most common associated co-morbidities of obesity, type 2 diabetes and hypertension, are highly prevalent health risks and are among the principal causes of death in the general population. Additionally, in third world countries, malnutrition is a very common cause of infection or death, especially in young children. Accordingly, knowledge of the basic elements of good nutrition and the biochemical pathways associated with the metabolism of protein, fat and carbohydrate offers important contributions to mitigate these health problems. The proposed dual degree program will provide the student with a core understanding of the mechanics of metabolism combined with advanced courses in public health and nutrition. This combined approach will yield a highly qualified and competitive public health practitioner trained to develop evidence based policy, programs, strategies and advocacy to address these health risks and problems.
    [Show full text]
  • The Healthy Core Metabolism: a New Paradigm for Primary Preventive Nutrition Anthony Fardet, Edmond Rock
    The Healthy Core Metabolism: A New Paradigm for Primary Preventive Nutrition Anthony Fardet, Edmond Rock To cite this version: Anthony Fardet, Edmond Rock. The Healthy Core Metabolism: A New Paradigm for Primary Pre- ventive Nutrition. Journal of Nutrition, Health and Aging, Springer Verlag (Germany), 2016, 20 (3), pp.239-247. 10.1007/s12603-015-0560-6. hal-01458429 HAL Id: hal-01458429 https://hal.archives-ouvertes.fr/hal-01458429 Submitted on 6 Feb 2017 HAL is a multi-disciplinary open access L’archive ouverte pluridisciplinaire HAL, est archive for the deposit and dissemination of sci- destinée au dépôt et à la diffusion de documents entific research documents, whether they are pub- scientifiques de niveau recherche, publiés ou non, lished or not. The documents may come from émanant des établissements d’enseignement et de teaching and research institutions in France or recherche français ou étrangers, des laboratoires abroad, or from public or private research centers. publics ou privés. J Nutr Health Aging Volume 20, Number 3, 2016 THE HEALTHY CORE METABOLISM: A NEW PARADIGM FOR PRIMARY PREVENTIVE NUTRITION A. FARDET, E. ROCK 1INRA, Human Nutrition Department, JRU 1019, UNH, CRNH Auvergne, F-63000 Clermont-Ferrand & Clermont Université, Université d’Auvergne, Unité de Nutrition Humaine, BP 10448, F-63000 Clermont-Ferrand, France. Corresponding author: Dr. Edmond Rock, INRA, Human Nutrition Department, JRU 1019, UNH, CRNH Auvergne, F-63000 Clermont- Ferrand & Clermont Université, Université d’Auvergne, Unité de Nutrition Humaine, BP 10448, F-63000 Clermont-Ferrand, France, +33 (0)4 73 62 41 69, fax +33 (0)4 73 62 46 38, E-mail: [email protected] Abstract: Research in preventive nutrition aims at elucidating mechanism by which our diet helps us to remain in good health through optimal physiological functions.
    [Show full text]
  • Journal of Obesity and Nutritional Disorders
    Journal of Obesity and Nutritional Disorders Sparre M and Kristensen G. J Obes Nutr Disord: JOND-116. Review Article DOI: 10.29011/JOND-116.100016 Casualties of the Danish Malnutrition Period Maja Sparre1*, Gustav Kristensen2 1Geriatric Department, University Hospital Gentofte, Hellerup, Denmark 2Econometric Department, Stockholm School of Economics, Latvia *Corresponding Author: Maja Sparre, Geriatric Department, University hospital Gentofte, Niels Andersensvej 28, 2900 Hellerup, Denmark. Tel: +4538673867; Fax: +4538677632; Email: [email protected] Citation: Sparre M, Kristensen G (2017) Casualties of the Danish Malnutrition Period. J Obes Nutr Disord: JOND-116. DOI: 10.29011/JOND-116.100016 Received Date: 20 September, 2017; Accepted Date: 28 October, 2017; Published Date: 03 November, 2017 Abstract From 1999 to 2007 the number of people who died from malnutrition in Denmark rose suddenly, in some parts of the country up to 8 times. Inspired by the Dutch famine studies we examine that the death rates from diseases causing malnutrition. We find a parallel to the Dutch famine studies in that it seems that patients suffering from schizophrenia, stroke and Alzheimer’s disease also in excess during this period. Abbreviations: during this period show that they have an increased risk of devel- oping schizophrenia, diabetes, cold, breast cancer and Alzheimer’s DMP : The Danish Malnutrition Period Disease(AD) and have an altogether higher all-cause mortality [l-3]. AD : Alzheimer's Disease The Danish malnutrition period (DMP) 1999- Keywords:
    [Show full text]
  • International Prevalences of Reported Food Allergies and Intolerances
    European Journal of Clinical Nutrition (2001) 55, 298±304 ß 2001 Nature Publishing Group All rights reserved 0954±3007/01 $15.00 www.nature.com/ejcn International prevalences of reported food allergies and intolerances. Comparisons arising from the European Community Respiratory Health Survey (ECRHS) 1991 ± 1994 RK Woods1*, M Abramson1, M Bailey1 and EH Walters2 on behalf of the European Community Respiratory Health Survey (ECRHS) 1Departments of Epidemiology and Preventive Medicine, Monash Medical School, The Alfred Hospital, Prahran, Victoria, Australia; and 2Department of Respiratory Medicine, Monash Medical School, The Alfred Hospital, Prahran, Victoria, Australia Objective: The aim of this study was to report the prevalence, type and reported symptoms associated with food intolerance. Design: A cross-sectional epidemiological study involving 15 countries using standardized methodology. Participants answered a detailed interviewer-administered questionnaire and took part in blood, lung function and skin prick tests to common aeroallergens. Setting: Randomly selected adults who took part in the second phase of the European Community Respiratory Health Survey (ECRHS). Subjects: The subjects were 17 280 adults aged 20 ± 44 y. Results: Twelve percent of respondents reported food allergy=intolerance (range 4.6% in Spain to 19.1% in Australia). Atopic females who had wheezed in the past 12 months, ever had asthma or were currently taking oral asthma medications were signi®cantly more likely to report food allergy=intolerance. Participants from Scandi- navia or Germany were signi®cantly more likely than those from Spain to report food allergy=intolerance. Respondents who reported breathlessness as a food-related symptom were more likely to have wheezed in the past 12 months, to have asthma, use oral asthma medications, be atopic, have bronchial hyperreactivity, be older and reside in Scandinavia.
    [Show full text]