The Marine Biological Laboratory and the University of Chicago Retreat

At the Marine Biological Laboratory 7 MBL Street Woods Hole, MA

MAY 2 - 4, 2014

Biological MBL Discovery in Woods Hole WELCOME

Bringing the Best Together

The MBL has always been an intellectual crossroads: a place where the best students and most creative scientists from around the world gather to do some of their most exciting work. Many have used, as model systems, the marine and aquatic organisms found in nearby waters.

The MBL is also a place for discovery, where entire fields of study—neurobiology, nurtured and developed. Today our scientists are charting new directions embryology, cell biology, and environmental sciences, for example—have been in biological discovery that span studies ranging from microbial genomics to regenerative biology to coastal resiliency.

This weekend marks another important milestone as we welcome our UChicago and Argonne colleagues to Woods Hole for the second in a series of joint retreats. Although not yet the start of the explosive summer season and the arrival of hundreds of visiting scientists, course faculty, and students, you will be able to see firsthand what much of the MBL is all about. Over the next few days we will continue for the future of research and education at our institutions. the conversation that began in Chicago this winter about what our affiliation means Thank you for your commitment to this important effort. I invite everyone to think boldly this weekend, and to imagine future collaborations and discoveries that would only be possible because of our new partnership.

— Joan V. Ruderman, President and Director, MBL

MBL AND UCHICAGO RETREAT PLANNING COMMITTEE: John Cunningham, Pediatrics, University of Chicago Amy Gladfelter, Dartmouth College, Adjunct Scientist and Whitman Investigator, MBL Julie Huber, Bay Paul Center, MBL Karl Matlin, Surgery, University of Chicago, Co-chair Leslie Osborne, Neurobiology, University of Chicago Joel Smith, Eugene Bell Center, MBL, Co-chair Joe Thornton, Ecology and Evolution, University of Chicago Mark Westneat, Organismal Biology and Anatomy, University of Chicago Joe Vallino, Ecosystems Center, MBL Steve Zottoli, Williams College, Adjunct Senior Scientist and Whitman Investigator, MBL Joining Forces: Concrete Steps Towards a New Era in Discovery Biology

Sessions are in Lillie Auditorium unless otherwise noted.

9:00 - 10:00AM environment demands we take a broad view of how RETREAT GOALS: microbial communities connect seemingly disparate FRIDAY BREAKOUT SESSION I — “Big Questions” ARRIVAL, POSTERS, AND MIXER fields of study. The breadth of MBL, UChicago, and MAY 2 Acquaint University of Chicago Which 3-4 important scientific questions are the Argonne research interests uniquely positions us to and Argonne participants with 4:00 PM - on affiliated institutions best positioned to address lead analysis of microbial communities relevant from teaching and research facilities Registration, Flexible Arrival, Swope Center Lobby at a world-class level? biomedicine to human impact on ecosystems. at the MBL. 5:00 - 7:00 PM Session Introduction: Jonathan Gitlin, Deputy Director Mitchell Sogin, Senior Scientist, MBL Allow attendees to get Dinner, Swope Center Dining Room of Research and Programs, MBL Vanessa Leone, Postdoctoral Scholar, Gastroenterology, acquainted and to engage with Hepatology, and Nutrition, UChicago Medical Center MBL summer investigators and 7:00 - 10:00 PM 10:00 - 10:30 AM course directors. Poster Session and Mixer, Swope Center Lobby Coffee Break, Lillie Lobby 12:15 - 1:15 PM Lunch, Swope Center Dining Room Identify the “Big Questions” that 10:30 - 11:15 AM the affiliated institutions should Large-Group Discussion of “Big Questions” 1:15 - 2:15 PM pursue together. Breakout Session Lightning Tours (Meet in Swope Center Lobby) SATURDAY BREAKOUT SESSIONS, THEME TALKS, Loeb teaching labs, National Xenopus Resource, Identify the “Big Priorities” that MAY 3 AND LIGHTNING TOURS OF MBL FACILITIES 11:15 - 11:45 AM Rowe visiting scientist labs, Marine Resources Center will enable pursuit of the “Big Theme 1: Marine and Aquatic Organisms for Questions.” 7:00 - 8:30 AM Discovery Biology Jennifer Morgan, Associate Director, Bell Center and Breakfast, Swope Center Dining Room Woods Hole was chosen as the site for the Marine Associate Scientist, MBL Develop plans for white papers, Biological Laboratory because of the diversity of flora William Green, Professor, Department of Neurobiology, position pieces, and funding in 8:30 - 8:45 AM and fauna found in the local waters, marshes, and UChicago, and Whitman Investigator, MBL thematic areas. Opening Remarks, Lillie Auditorium estuaries. This diversity provides a unique biological context to conduct discovery research, in many cases 2:15 - 3:00 PM Joan Ruderman, President and Director, MBL with a focus on biomedical-related discoveries with Theme 3: The Incubator for Innovation in Imaging Neil Shubin, Robert R. Bensley Professor, Organismal new techniques available in genomics, modeling, The MBL has been a critical meeting place for Biology and Anatomy; and Senior Advisor to the and imaging. the world of imaging, where developers of new As part of a UChicago Career President and Vice President for Research and microscopes test-drive instruments on the varied cells Trek, eight UChicago students National Laboratories, UChicago Jennifer Morgan, Associate Director, Bell Center and and problems studied by MBL scientists and in our spent a day discovering MBL Associate Scientist, MBL courses. The “Incubator” provides a model for how we science. While at MBL, the 8:45 - 9:00 AM Joseph Thornton, Professor, Ecology and Evolution, take advantage of our diversity of research interests students fertilized sea urchin eggs, Recap of the February Retreat: Emerging Themes UChicago and our convening power. toured MBL research facilities, and Ideas and learned about cephalopod 11:45 - 12:15 PM Amy Gladfelter, Associate Professor, Dartmouth camouflage, sea lamprey Karl Matlin, Professor and Vice Chairman of Theme 2: Microbes in Human and Environmental College; Adjunct Scientist, and Whitman Investigator, regeneration, the Encyclopedia of Research, Department of Surgery, UChicago MBL Life, and science journalism. Health Linda Deegan, Senior Scientist, Ecosystems Center, MBL To understand how microbial populations affect areas Rick Fehon, Professor and Chairman, Molecular as diverse as human disease and the “health” of the Genetics and Cell Biology, UChicago JOINING FORCES | MBL-UChicago Retreat | May 2-4, 2014

Shaunae Alex, one of eight UChicago undergraduates doing research this summer at MBL under the Metcalf program, will work with Maureen Conte in Ecosystems: “Without a doubt, having the opportunity to intern at MBL is exciting and will have a strong Optional Afternoon Sessions impact on my future education!” 1:45 - 3:00 PM (Concurrent)

Federal Relations Update: Pursuing new research opportunities within the challenging fiscal climate in Washington, D.C. The session will include a brief presentation by Matt 3:00 - 3:30 PM 7:00 - 9:00 AM SUNDAY Greenwald, UChicago Assistant Vice President for Coffee Break, Lillie Lobby Breakfast, Swope Center Dining Room MAY 4 Federal Relations, on the budget and political outlook in Washington, including highlighting some of the 3:30 - 4:00 PM 9:00 - 9:45 AM initiatives at key federal research agencies, as well as Theme 4: Genomes to Global Cycles Theme 5: Complexity and Computation solicit feedback and discuss potential topic areas for The evolution and expression of genes in organisms Computational approaches for analyzing patterns of follow-up engagement in Washington. (Lillie Auditorium) — from microbial to multicellular — strongly gene expression, neural signaling, and the behavior Postdoc and Graduate Student Opportunities influence processes occurring across multiple scales, of organisms and ecosystems are remarkably similar. This session will be led by MBL postdoc Susan Banks from micro-niches in soil to biogeochemical processes All involve sifting out the underlying simplicity from and UChicago graduate student Thomas Stewart operating globally. Understanding how genomic complex data. Resource sharing and increased and will consider potential points of collaboration information gives rise to macroscopic processes interaction between the affiliated institutions provide between UChicago and MBL trainees with a focus on across many scales requires integration between a an exceptional opportunity for biological discovery. joint professional development programs, research multitude of disciplines. symposiums, grant/fellowship support, and teaching Leslie Osborne, Assistant Professor, Department of opportunities. Julie Huber, Bay Paul Center Associate Director Neurobiology, UChicago (Loeb 263) and Associate Scientist, MBL Ed Rastetter, Ecosystems Center Associate Director and Albert Colman, Assistant Professor, Geophysical Senior Scientist, MBL Sciences, UChicago 3:15 - 4:30 PM 9:45 - 10:15 AM New Education Programs at the MBL: How will 4:00 - 5:00 PM Coffee Break, Lillie Lobby future programs translate into infrastructure needs BREAKOUT SESSION II — From “Big Questions” to ensure success? to “Big Priorities” 10:15 AM - 12:00 PM In this session Neil Shubin will outline the portfolio BREAKOUT SESSION III — Interest Group of new educational programs being envisioned by What are the 2-3 highest cross-cutting priorities for Meetings to Jump-Start Collaborations the MBL/UChicago faculty. There are a number of focused attention needed to advance the 3-4 most active calls for proposals inviting UChicago faculty to important scientific questions? What are the critical, actionable first steps for collaboratively propose Graduate Courses, Conferences advancing collaborations in specific areas? and Workshops, and offer Graduate Student Research 5:00 - 5:45 PM Awards at the MBL. A dialogue with faculty and Large-Group Discussion of From “Big Questions” 12:00 - 12:30 PM available operational leads in several areas will help to “Big Priorities” Breakout Session Concluding Remarks inform planning priorities for both faculty and the operational support staff. Additional dialogue will explore the mechanics of preparing proposals for new 5:45 - 7:00 PM Joan Ruderman, President and Director, MBL education programs Cocktails and Raw Bar, Swope Center Terrace Neil Shubin, Robert R. Bensley Professor, Organismal Biology and Anatomy; and Senior Advisor to the at the MBL. (Lillie Auditorium) 7:00 - 9:00 PM President and Vice President for Research and Lobster Banquet, Swope Center Dining Room National Laboratories, UChicago

12:30 - 1:30 PM PHOTOS : Cover: MBL campus on Eel Pond (Tom Kleindinst). Inside cover: (upper) Loligo (squid) tentacle by Karen Crawford; (lower) Marine Resources Manager David Remsen; Lunch (take-away lunches available on request) MBL Embryology course, Semester in Environmental Science student in the field (Tom Kleindinst). P. 2: UChicago students visit MBL as part of the University’s Career Advancement Swope Center Dining Room program (Diana Kenney). P. 3: (background) dividing Spisula (clam) cells (Robert Palazzo); (left to right) Asterias (starfish) (MBL Science Journalism Program); UChicago main quad (Robert Kozloff); MBL’s R/V Gemma (Daniel Cojanu). P. 4: Metcalf Program student Shaunae Alex (Shaunae Alex); P. 5: (top to bottom) The White House (Wikipedia); MBL’s Semester in Environmental Science undergraduate program (Tom Kleindinst); An aerial view of the UChicago campus from the Midway Plaisance (University of Chicago); UChicago classroom (University of Chicago); Entrance to MBL’s Lillie building (Elizabeth Armstrong). Back cover: MBL-UChicago February 2014 retreat participants at the Biological Sciences Learning Center on the UChicago campus (Joel Wintermantle). MBL-UChicago Retreat University of Chicago February 2014

For more information about the MBL-University of Chicago Affiliation: www.mbl.edu/uc-affiliation

Biological Discovery MBL in Woods Hole