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Recommendation for Promotion and Tenure 785-864-1753 [email protected] July, 2013 Xinmai Yang Assistant Professor Department of Mechanical Engineering The University of Kansas I. Education Ph. D. Mechanical Engineering, Boston University, Boston, MA, May 2003 M. E. Solid Mechanics, Xi’an Jiaotong University, Xi’an, PR China, June 2000 B. E. Engineering Mechanics, Xi’an Jiaotong University, Xi’an, PR China, June 1997 II. Employment history 8/2008-present Assistant Professor, Mechanical Engineering, University of Kansas 3/2006-8/2008 Postdoctoral Research Associate, Biomedical Engineering, Washington University in St. Louis 6/2003-2/2006 Postdoctoral Research Associate, National Center for Physical Acoustics, University of Mississippi 1/2000-5/2003 Graduate Research Assistant, Mechanical Engineering, Boston University III. Research interests Photoacoustic/ultrasound imaging Therapeutic ultrasound Combination of ultrasound and laser for diagnosis and therapy I. Research record A. Research Publications Peer-reviewed journal publications 28. Huizhong Cui, Ti Zhang, and Xinmai Yang, “Laser-enhanced cavitation during high intensity focused ultrasound: An in vivo study,” Applied Physics Letters, 102 (13), 133702-133702-4 (2013). 27. Ti Zhang, Huizhong Cui, Chia-Yi Fang, Long-Jyun Su, Shenqiang Ren, Huan-Cheng Chang, Xinmai Yang, and M. Laird Forrest, “photoacoustic contrast imaging of biological tissues with nanodiamonds fabricated for high near-infrared absorbance,” Journal of Biomedical Optics, Vol. 18, 026018 (2013). Page 1 785-864-1753 [email protected] July, 2013 26. Huizhong Cui and Xinmai Yang, “Laser enhanced high-intensity focused ultrasound thrombolysis: an in vitro study,” Journal of the Acoustical Society of America, Vol. 133(2), EL123 (2013). 25. Janggun Jo, Hongyu Zhang, Paul D. Cheney, and Xinmai Yang, “Photoacoustic detection of functional responses in the motor cortex of awake behaving monkey during forelimb movement,” Journal of Biomedical Optics, Vol. 17, 110503 (2012). 24. Huizhong Cui and Xinmai Yang, “Enhanced heating effect during photoacoustic imaging guided high intensity focused ultrasound,” Applied Physics Letters, 99, 231113 (2011). 23. Qiuhong Yang, Huizhong Cui, Shuang Cai, Xinmai Yang, and M. Laird Forrest “In vivo photoacoustic imaging of chemotherapy-induced apoptosis in squamous cell carcinoma using a near-infrared caspase-9 probe,” Journal of Biomedical Optics, 16, 116026 (2011). 22. Behrouz Soroushian and Xinmai Yang, “Measuring non-radiative relaxation time of fluorophores with biomedical applications by intensity-modulated laser induced photoacoustic effect,” Biomedical Optics Express, Vol. 2(10), 2749-2760 (2011). 21. Huizhong Cui and Xinmai Yang, “Real-time monitoring of high-intensity focused ultrasound ablations with photoacoustic technique: an in vitro study,” Medical Physics, Vol. 38, 5345 (2011). 20. Janggun Jo and Xinmai Yang, “Functional photoacoustic imaging to observe regional brain activation induced by cocaine hydrochloride,” Journal of Biomedical Optics, Vol. 16, 090505 (2011). 19. Janggun Jo and Xinmai Yang, “Detection of cocaine induced rat brain activation by photoacoustic tomography,” Journal of Neuroscience Methods, Vol. 195, 232-235 (2011). 18. Huizhong Cui and Xinmai Yang, “In-vivo imaging and treatment of solid tumor using integrated photoacoustic imaging and high intensity focused ultrasound system,” Medical Physics, Vol. 37, 4777-4781 (2010). 17. Jacob Staley, Patrick Grogan, Abbas K. Samadi, Huizhong Cui, Mark S. Cohen, and Xinmai Yang, “The growth of melanoma brain tumors monitored by photoacoustic microscopy,” Journal of Biomedical Optics, Vol. 15, 040510 (2010). 16. Huizhong Cui, Jacob Staley, and Xinmai Yang, “The integration of photoacoustic imaging and high intensity focused ultrasound,” Journal of Biomedical Optics, Vol. 15, 021312 (2010). 15. Xinmai Yang, Anastasio Maurudis, John Gamelin, Andre Aguirre, Quing Zhu, and Lihong V. Wang, “Photoacoustic tomography of small animal brain with a curved array transducer,” Journal of Biomedical Optics, Vol. 14, 054007 (2009). 14. Xinmai Yang, Erich. W. Stein, S. Ashkenazi, and Lihong V. Wang, “Nanoparticles for photoacoustic imaging,” Wiley interdisciplinary reviews: nanomedicine and Nanobiotechnology, Volume 1, Issue 3, 360-368 (2009). Page 2 785-864-1753 [email protected] July, 2013 13. Dipanjan Pan, Manojit Pramanik, Angana Senpan, Xinmai Yang, Kwang H. Song, Mike J. Scott, Huiying Zhang, Patrick J. Gaffney and Lihong V. Wang, “Molecular photoacoustic tomography with colloidal nanobeacons,” Angew. Chem. Int. Ed. 48, 4170-4173 (2009). 12. Xinmai Yang and Lihong V. Wang, “Monkey brain cortex imaging by photoacoustic tomography,” Journal of Biomedical Optics, Vol. 13, 044009 (2008). 11. Xinmai Yang, Sara E. Skrabalak, Zhi-Yuan Li, Younan Xia and Lihong V. Wang, “Photoacoustic tomography of a rat cerebral cortex in vivo with Au nanocages as an optical contrast agent,” Nano Letters. Vol. 7 (12) 3798-3802. (2007). 10. Xinmai Yang and Lihong V. Wang, “Photoacoustic tomography of a rat cerebral cortex with a ring-based ultrasonic virtual point detector,” Journal of Biomedical Optics. Vol. 12, 060507 (2007). 9. Xinmai Yang, Meng-lin Li, and Lihong V. Wang, “Ring-based ultrasonic virtual point detector with applications to photoacoustic tomography,” Appl. Phys. Lett. 90, 251103 (2007). 8. Lihong V. Wang and Xinmai Yang, “Boundary conditions in photoacoustic tomography and image reconstruction,” Journal of Biomedical Optics 12(01), 014027, January (2007). 7. Xinmai Yang and Charles C. Church, “A simple viscoelastic model for soft tissues in the frequency range 5 - 20 MH,” IEEE UFFC 53 (8), 1404-1411 (2006). 6. Xinmai Yang and Charles C. Church, “A model for the dynamics of gas bubbles in soft tissue,” J. Acoust. Soc. Am. 118(6), 3595-3906 (2005). 5. Xinmai Yang and Charles C. Church, “Nonlinear dynamics of gas bubbles in viscoelastic media,” Acoustics Research Letters Online, 6(3), 151-156, July (2005). 4. Xinmai Yang and Robin O. Cleveland, “Time domain simulation of nonlinear acoustic beams generated by rectangular pistons with application to harmonic imaging,” J. Acoust. Soc. Am. 117(1), 113-123, January (2005). 3. Xinmai Yang, Ronald A. Roy, and R. Glynn Holt, “Bubble dynamics and size distributions during focused ultrasound insonation,” J. Acoust. Soc. Am. 116(6) 3423-3431, December (2004). 2. JunQiang Zhu, Yapeng Shen, and Xinmai Yang, “Dynamic instability of laminated piezoelectric shell under the action of electric field and two-way compressive loads,” Hangkong Xuebao/Acta Aeronautica et Astronautica Sinica 24(1), January, 21-27 (2003). 1. Xinmai Yang and Yapeng Shen, “Dynamic instability of laminated piezoelectric shell,” Int. J. Solids & Structures, 38 (14): 2291-2303 (2001). Book Chapters 2. Xinmai Yang and Lihong V. Wang, “Virtual point detector using a ring in photoacoustic tomography,” In Photoacoustic imaging and spectroscopy, edited by L. Wang, (2009). Page 3 785-864-1753 [email protected] July, 2013 1. Xinmai Yang and Mark Cohen, “Melanoma to brain metastasis: photoacoustic microscopy,” In Tumors of the Central Nervous System, Volume 4, edited by M. A. Hayat, (2012). Conference Proceedings 18. Behrouz Soroushian and Xinmai Yang, “Measuring non-radiative relaxation time of fluorophores by intensity-modulated laser induced photoacoustic effect,” Proc. SPIE, Vol. 8581, 8581V, San Francisco, CA, 2013. 17. Qiuhong Yang, Huizhong Cui, Shuang Cai, M. Laird Forrest, and Xinmai Yang, “Photoacoustic imaging of chemotherapy-induced apoptosis in squamous cell carcinoma,” Proc. SPIE, Vol. 8223, 822306, San Francisco, CA, 2012. 16. Janggun Jo, Hongyu Zhang, Paul Cheney, and Xinmai Yang, “Photoacoustic imaging of functional domains in primary motor cortex in Rhesus Macaques,” Proc. SPIE, Vol. 8223, 822308, San Francisco, CA, 2012. 15. Huizhong Cui and Xinmai Yang, “Monitoring of HIFU thermal damage using integrated photoacoustic imaging and high intensity focused ultrasound technique,” Proc. SPIE, Vol. 7899, San Francisco, CA, 2011. 14. Janggun Jo and Xinmai Yang, “Photoacoustic imaging to detect rat brain activation after cocaine hydrochloride injection,” Proc. SPIE, Vol. 7899, San Francisco, CA, 2011. 13. Huizhong Cui, Jacob Staley, and Xinmai Yang, “A combined photoacoustic imaging and high intensity focused ultrasound system,” Proc. SPIE, Vol. 7564, San Francisco, CA, 2010. 12. Xinmai Yang, Anastasios Maurudis, John Gamelin, Andres Aguirre, Quing Zhu, and Lihong Wang, “Three-dimensional photoacoustic tomography of small animal brain with a curved array transducer,” Proc. SPIE, Vol. 7177, San Jose, CA, 2009. 11. Xinmai Yang, Sara Skrabalak, Erich Stein, Bin Wu, Xunbin Wei, Younan Xia, and Lihong V. Wang, “Photoacoustic tomography with novel optical contrast agents based on gold nanocages or nanoparticles containing near-infrared dyes,” Proc. SPIE, Vol. 6856, 68560I, 2008. 10. Xinmai Yang and Lihong V. Wang, “Monkey brain cortex imaging by use of photoacoustic tomography,” Proc. SPIE, Vol. 6856, 685608, 2008. 9. Cheng-Ying Chou, Mark A. Anastasio, Jin Zhang, Geng Ku, Xinmai Yang, and Lihong V. Wang, “Multi-bandwidth image reconstruction in photoacoustic tomography,” Proc. SPIE, Vol. 6856, 68561G, 2008. 8. Xinmai Yang, Men-lin Li, and Lihong V. Wang, “Photoacoustic tomography with a virtual point detector,” Proc. of SPIE, Vol. 6437, 643718, 2007. 7. Xinmai Yang and Lihong V. Wang, “Boundary effects on image reconstruction in photoacoustic tomography,” Proc. of SPIE, Vol. 6437, 64370W, 2007. Page 4 785-864-1753 [email protected] July, 2013 6. Charles C. Church and Xinmai Yang,
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