The Festival of Genomics & Biodata

Time Time GMT EST The Festival of Genomics & Biodata - Agenda Day 1 An Update on Genomics in the NHS 9.00 4.00 Dame Sue Hill, CSO, NHS England

9.30 4.30 Seven Bridges - Talk Title TBA

10.00 5.00 KEYNOTES UK/EUROPE Keynote Plenary Panel Discussion

10.30 5.30 Poster Presentations + Exhibition Hall CLINICAL GENOMICS GENOMICS IN RESEARCH A GENOMICS IN RESEARCH B BIODATA CANCER GENOMICS MASTERMIND SESSIONS YOUNG SCIENTISTS Panel: Is Machine Learning the Key to Uncovering Genomic Evidence for Unlocking RWE? Reinfection with SARS-CoV-2: a Case Structural variants at BRCA1/2 and Clinical Microbial Metagenomics and Exploring the Clinical Application of Study HR deficiency in Tumours Fecal Microbiota Transplantation Single Cell Analysis in Liquid Biopsy Paul Agapow, Health Informatics Director, Interactive sessions moderated with 11.00 6.00 AstraZeneca 3-4 starting contributors & audience Joel R Sevinsky, Principal, Theiagen Ailith Ewing, UKRI Innovation Fellow, Florian Fricke, Professor, University Victor Neduva, Senior Principal Scientist, Bernhard Polzer, Head of Molecular participation Consulting LLC University of Edinburgh of Hohenheim MSD Diagnostics, Fraunhofer ITEM Sponsored by Qiagen Natalie Gavrielov, Senior Data Scientist, Roche

11.30 6.30 Shaping the Disease Microbiome with A Complete Workflow for Analysis of 11.40 6.40 Dietary and Lifestyle Interventions cfDNA: From Plasma to Variants Panel: COVID-19 & Genomics - The Sponsor slot available - email BIONANO Genomics- Talk title to be Gianni Panagiotou, Head Systems Biology Nicole Roseman, IDT UK's response [email protected] for announced shortly and Bioinformatics, Leibniz Institute of Shilpa Parakh, Beckman Coulter Life details

Natural Product Research and Infection Sciences MASTERMIND Angela Douglas, Deputy CSO, NHS Biology Hans Knoll Institute(HKI) LIQUID BIOPSY Sponsored by Beckman Coulter Life

GENOMIC MEDICINE England Sponsored by Novogene Sciences HUMAN MICROBIOMEHUMAN 11.50 6.50 Tom Fowler, Deputy Chief Scientist, Genomics England A Time to Sequence in Clinical Machine Learning Approaches to

STRUCTURAL VARIATION STRUCTURAL DETECTION How can we support and foster Richard Scott, Clinical Director, Cytogenetics The Gut Microbiome in ANALYSIS GENOME ADVANCING DATA Drug Resistance and Variant Effect Addressing the Challenges of Pre- innovation in the UK Genomics Genomics England Inflammatory Bowel Diseases Prediction Analytics of Liquid Biopsies ecosystem via entrepreneurship? 12.00 7.00 Naomi Allen, Chief Scientist, UK Cynthia Morton, Director of BioBank Cytogenetics, Brigham and Women’s Melanie Schirmer, Group Leader, John Overington, Chief Information Pamela Pinzani, Associate Professor, Karen Spink, Innovate UK Hospital, and Institute Member, Technical University Munich Officer, Catapult Medicines University of Florence Broad Institute of MIT and Harvard Discovery Live Lounge Lunch Talks

12.30 7.30 Saliva as a diagnostic tool for COVID-19: A comprehensive extraction-based workflow from collection to detection - Kiranmai Durvasula, Product Manager, Omega Bio-tek, Inc

12.45 7.45 Seven Bridges - Talk title to be announced shortly

13.00 8.00 LabTech - Talk title to be announced shortly

13.15 8.15 Deciphering the Methylome: Enzymatic Methyl-seq, a new alternative to bisulfite sequencing - Adam Peltan, Senior NGS Technical Application Specialist, New England Biolabs

13.30 8.30 Networking Break + Exhibition Hall

CLINICAL GENOMICS GENOMICS IN RESEARCH A GENOMICS IN RESEARCH B BIODATA CANCER GENOMICS MASTERMIND SESSIONS YOUNG SCIENTISTS

The Microbiome of Idiopathic Exploiting the Multiple Modalities Exploring the Somatic-Germline Genomically Humanised Mouse Clinical Utility of Liquid Biopsies Neurodegenerative Diseases Underpinning Population Diversity Interface in Precision Oncology: A Models of Neurodegenerative (MIND) using AI and XAI Clinical Perspective Disease Interactive sessions moderated with 13.40 8.40 Klaus Pantel, Chairman, Department 3-4 starting contributors & audience of Tumor Biology, University Medical J. Christopher Ellis, Senior Staff Jean-Baptiste Cazier, Director of the Anju Kulkarni, Consultant Genetic Thomas Cunningham, Senior participation Center Hamburg-Eppendorf Scientist, Oak Ridge National Centre for Computational Biology, Counsellor, Guy's and St Thomas' Investigator Scientist, MRC Laboratory University of Birmingham NHS Foundation Trust 4 poster presentations from Young 14.10 9.10 CRISPR Validation and Resolving Scientists Complex Genomics Landscapes with Xdrop™ Sponsor slot available - email Eppendorf - Talk title to be Promega - Talk title to be 14.20 9.20 [email protected] for Peter Mouritzen, Vice President announced shortly announced shortly details Application and Market

Development, Samplix MASTERMIND

YOUNG SCIENTISTS CLINICAL SEQUENCING

14.30 9.30 Sponsored by Samplix PRECISION ONCOLOGY MICROBIOME SEQUENCING Accelerating the speed of discovery: Case Study: Liquid Biopsy Mining the Unannotated Human Precision Oncology Therapeutic ADVANCING GENOME DATA ANALYSIS GENOME ADVANCING DATA Exome Sequencing of Large Cohorts Improving NGS success rates while Proteome Reveals a Novel DoMI, a Database of Microbe-Host Development Can Guide Drug Discovery reducing costs

Catherine Alix-Panabieres, Director GENOME COMPLEXITY ENGINEERED VALIDATING Regulator of mTOR Signaling Interactions for Drug Discovery 14.40 9.40 of Laboratory of Rare Human Andrew Biankin, Director of the Paul Nioi, Senior Director, Research, Ana Dinarina, Thermo Fisher Circulating Cells, The University of Alexandra Khitun, Postdoctoral Julia Maritz, Senior Scientist, Merck Wolfson Wohl Cancer Research Alnylam Pharmaceuticals Scientific Montpellier Researcher, Harvard University Centre, University of Glasgow

15.10 10.10 Poster Presentations + Exhibition Hall CLINICAL GENOMICS GENOMICS IN RESEARCH A GENOMICS IN RESEARCH B BIODATA CANCER GENOMICS MASTERMIND SESSIONS YOUNG SCIENTISTS Panel: Are Long-Reads the End of Short- Reads? Using Whole Exome Sequencing Talk Title TBA David Smith, Professor, Mayo Clinic Digital Pathology at the Intersection Data to Understand Autoimmune NGS in CRUK's Precision Oncology of Genomics, Big Data and AI Phenotype Portfolio Mike Hubank, Head of Clinical Genomics, Interactive sessions moderated with 15.40 10.40 Meriel McEntagart, Consultant The Royal Marsden NHS Foundation Trust 3-4 starting contributors & audience Geneticist, St George's University Matt Loose, Professor, University of Steven Hart, Senior Associate Sarah Ennis, Professor of Genomics Maria Antonietta Cerone, Research participation Hospital Nottingham Consultant, Mayo Clinic with Medicine, University of Programme Manager, CRUK Andrew Beggs, Professor, University of Southampton Birmingham 16.10 11.10 Identification of 370 Loci for Age at Onset Enabling Genomic Medicine: of Sexual and Reproductive Behaviour, Analysis at Scale Highlighting Common Aetiology with Sponsor slot available - email Sponsor slot available - email Reproductive Biology, Externalizing Eurofins - Talk title to be announced 16.20 11.20 [email protected] for [email protected] for Behaviour and Longevity Nick Lench, Chief Scientific Officer, shortly details details Congenica

Natalie van Zuydam, Senior Statistician, NGS TESTING Sponsored by Congenica MASTERMIND

Data Science and Quantitative Biology, YOUNG SCIENTISTS GENOMIC MEDICINE 16.30 11.30 AstraZeneca 4 poster presentations from Young

LONG SEQ RANGE & MAPPING Scientists Integrating Genomics into Routine From Monogenic to Complex Opportunities and Challenges of

Using Hybrid Genome Assembly to Histogenomics and Beyond: ANALYSIS GENOME ADVANCING DATA NGS Technologies that are Driving

Clinical Practice: Improving HISTO-GENOMICS & DIGITAL PATHOLOGY Disease – Evolving Insights from Applying ML to Biological Explore Plasmid Diversity in Non- Unleashing the Power of Digital New Cancer Therapies Outcomes and Avoiding Harm Genetic Rare Diseases Experiments Clinical Bacterial Populations Pathology for Precision Medicine 16.40 11.40 Jadwiga Bienkowska, Senior John McDermott, Academic Clinical Guillermo del Angel, Sr. Director, Annalisa Pawlosky, Research Liam Shaw, Postdoctoral Fellow, George Yousef, Chief of Paediatric Director, Head of Computation Fellow, Manchester Centre for Data Science, Genomics and Scientist, Google University of Oxford Laboratory Medicine, SickKids Biology Oncology R&D, Pfizer Genomic Medicine Bioinformatics, Alexion

17.10 12.10 Networking Break + Exhibition Hall

NHGRI's Genomic Strategic Plan 17.30 12.30 Eric Green, Director, National Human Genome Research Institute

Advancing Medicine Through Data Sharing and Collaboration on a Global Scale 18.00 13.00

GLOBAL KEYNOTES GLOBAL Heidi Rehm, Chief Genomics Officer, Massachusetts General Hospital, and Institute Member, Broad Institute of MIT and Harvard

18.30 13.30 Post-Festival activity – announcement coming soon Time Time GMT EST The Festival of Genomics & Biodata - Agenda Day 2

9.00 4.00 Lord Bethell of Romford, Parliamentary Under Secretary of State (Minister for Innovation), UK Department of Health and Social Care

Ready for Lift Off: The Next Decade of Human Genomics 9.30 4.30 Ashley Van Zeeland, PhD. MBA, Vice President, Product Integration and Customer Collaboration, Illumina

Updates on the UK Biobank for 2021 and Beyond

10.00 5.00 KEYNOTES UK/EUROPE Mark Effingham, Deputy CEO, UK BioBank

10.30 5.30 Poster Presentations + Exhibiton Hall CLINICAL APPLICATIONS OF DRUG DISCOVERY AND RESEARCH TECHNOLOGY HEALTHCARE DATA RARE DISEASES MASTERMIND SESSIONS START-UP ZONE GENOMICS DEVELOPMENT Using Genetics to Understand the Using Genomics to Track and Defeat Translational of Rare Disease Going Beyond FAIR to Create a Excess Risk of Cardiometabolic COVID-19 Research to Practice Talk Title TBA Connected Data Ecosystem Disease in Individuals with Severe Sharon Peacock, Professor of Mental Illness Interactive sessions moderated with 11.00 6.00 Larissa Kerecuk, Rare disease Lead Microbiology, Cambridge University and Steven Hardy, Head of Molecular Susan Gregurick, Associate Director 3-4 starting contributors & audience and Clinical research specialty lead, Director of COG-UK Diagnostics, Public Health England for Data Science, National Institutes Rona Strawbridge, Rutherford Fund participation NIHR and Birmingham Women's and Judith Breuer, Professor of Virology and of Health Fellowship at HDR-UK, UKRI Children's Hospital Director, Pathogen Genomics Unit at UCL Innovation 11.30 6.30 From persisting Borrelia to chronic Lyme Clinical Genomics: Analysis of simple & complex variants & biomarkers for disease: Vitality of atypical and persistent comprehensive genomic profiling (CGP) of forms of Lyme disease spirochetes Sponsor slot available - email Sponsor slot available - email Accelerating Research in the Cloud solid tumors & hematologic malignancies Libor Grubhoffer, Professor of Molecular [email protected] for [email protected] for 11.40 6.40 using a single NGS workflow and Cell Biology and Genetics, University details details Raed Samara, Associate Director, Global of South Bohemia Rowland Illing, Director and CMO ONCOLOGY

Product Management, NGS, QIAGEN MASTERMINDS Government Healthcare, AWS Sponsored by ThermoFisher DATA HEALTHCARE Sponsored by QIAGEN 11.50 6.50 INFECTIOUS DISEASES Pete Sinden, CIO, Genomics England Using Genomics for Tracking COVID COMPANION DIAGNOSTICS Mark Effingham, Deputy CEO, UK FLT3 inhibitors added to induction European Joint Programme on Rare Reinfection Rates and Contact Biobank Using Human Genetics to Improve therapy result in deeper remissions: Diseases Tracing to Inform on Public Health Rob Denison, CIO, Congenica the Odds of Drug Development Interactive sessions moderated with evidence from a novel assay for Issues 3-4 starting contributors & audience 12.00 7.00 measurable residual disease (MRD) Daria Julkowska, Assistant Director, Sponsored by Amazon Michael Holmes, Professor, Medical participation Thematic Institute of Genetics, Mark Pandori, Director, Nevada State Research Council, Population Health Ken Chang, Director of Clinical Genomics & Bioinformatics, INSERM, Public Health Laboratory, University Research Unit, University of Oxford Biomarkers, Daiichi Sankyo Co-ordinator, EJRP of Nevada

12.30 7.30 AltemisLab - Talk title to be announced shortly

12.45 7.45 Hamilton - Talk title to be announced shortly

13.00 8.00 AWMGS - Talk title to be announced shortly

13.15 8.15

13.30 8.30 Networking Break + Exhibition Hall

CLINICAL APPLICATIONS OF DRUG DISCOVERY AND RESEARCH TECHNOLOGY HEALTHCARE DATA RARE DISEASES MASTERMIND SESSIONS START-UP ZONE GENOMICS DEVELOPMENT Patient-Centered Precision Health In 13.40 8.40 Gene Discovery in severe psychiatric Opening A Learning Health Care System: Pharmacogenomics in Drug An Approach to Nanopore Leveraging Human Genetic Studies disorders at Boston Children’s Geisinger’s Genomic Medicine Discovery Sequencing for Identification of New Targets Hospital Interactive sessions moderated with Experience How innovators can get support in 3-4 starting contributors & audience Charles Cox, Head of Wojciech Makalowski, Professor, Nilanjana Sadhu, Research Scientist, the UK genomics ecosystem 14.00 9.00 Catherine Brownstein, Professor, participation Marc Williams, Director of Genomic Pharmacogenetics, GSK University of Munster Biogen Harvard Medicine Insitute, Geisinger Joanne Hackett, Head of Genomic and Precision Medicine, IQVIA 14.10 9.10

Sponsor slot available - email Sponsor slot available - email Sponsor slot available - email Sponsor slot available - email Oxford Nanopore - Talk title to be 14.20 9.20 [email protected] for [email protected] for [email protected] for [email protected] for announced shortly Accessing Funding

details details details details

RARE DISEASES

MASTERMINDS

START-UP ZONE START-UP

HEALTHCARE DATA HEALTHCARE

GENOMIC MEDICINE PHARMACOGENOMICS

14.30 9.30 NANOPORE SEQUENCING Panel: What Data is Available in the 3D Health Initiative and Genomic Discussion: Polygenic Risk Scores in Assembling the Genome of the Healthcare System? Efforts at UCSF The Open Science Experience of the Pharmacogenomics Tasmanian Devil with Oxford Interactive sessions moderated with A Founder's Story Rare Disease Community Nanopore Ashlee Hamel, System Manager, 3-4 starting contributors & audience 14.40 9.40 Aleks Rajkovic, Chief Genomics Charles Paulding, Senior Director, Pharmacy Clinical Programs, Sentara participation Patrick Short, Founder & CEO, Sano Officer, UCSF Pharmacogenomics, Regeneron Segolene Ayme, Medical Geneticist, Zemin Ning, Senior Scientific Healthcare Genetics Sawona Biswas, Director of 3D Aviv Madar, Lead Analyst, Novartis INSERM Manager, Wellcome Sanger Institute Elizabeth George, Director, Digital Health study, University of California Sridevi Ponduru, Medical Director, Takeda Clinical Trials, GSK 15.10 10.10 Poster Presentations + Exhibition Hall CLINICAL APPLICATIONS OF DRUG DISCOVERY AND RESEARCH TECHNOLOGY HEALTHCARE DATA RARE DISEASES MASTERMIND SESSIONS START-UP ZONE GENOMICS DEVELOPMENT Are Phenotyping Algorithms Fair for Talk Title TBA Harnessing Synthetic Biology and Discussion: The Merits and Functional Genomics for Drug Underrepresented Minorities The Importance of Specialised Deep Learning to Fight Pandemics Shortfalls of Different Technologies Discovery Within Older Adults? Nursing for Rare Diseases Andrew Feber, Deputy Director of 15.40 10.40 Clinical Genomics & Translational Office Hours: Sessions to support James J. Collins, Professor, MIT, and David Smith, Professor, Mayo Clinic Christopher Miller, Head of Juan M. Banda, Assistant Professor Gill Moss, Clinical Nurse Lead for Epigenetic Group Lead, The Royal new entrepeneurs & showcase start- Institute Member, Broad Institute of Shawn Baker, Advisor, Functional Genomics, GSK of Computer Science, Georgia State Rare Diseases, NHS Marsden, NHS Foundation Trust, up companies MIT and Harvard SanDiegOmics University Bahram Arezi, Head of NGS Library Prep, Agilent 16.10 11.10 Digital PCR Mutation Assays with Pooled CRISPR Screens Identify Improving Drug Discovery with Locked Nucleic Acid (LNA) Why Diversity Matters in Human Novel Targets and Resistance to Large Scale Genomics Technology for Rare Target Genomics Research Sponsor slot available - email Office Hours: Sessions to support Cancer Treatments Detection 16.20 11.20 [email protected] for new entrepeneurs & showcase start- Neil Ward, Senior Sales Director, Daniel Heinz Löfgren, Market Samira Asgari, Postdoctoral Research details up companies Miika Ahdesmaki, Principal Scientist, North Europe, Illumina Development Manager, PCR/dPCR -

Fellow, Harvard Medical School RARE DISEASES MASTERMINDS

Associate Director, AstraZeneca Sponsored by Illumina EMEA/CP, Qiagen ZONE START-UP EQUITABLE ACCESS EQUITABLE 16.30 11.30 Sponsored by Qiagen

SEQUENCING TECH LANDSCAPE TECH SEQUENCING How Can We Balance the Ethical Rapid Whole Genome Sequencing- Imperative for Scientific Progress Informed Precision Medicine for

Rewriting the Genetic Code ID, VALIDATION TARGET & PRIORITISATION Genomics in Target ID with the Ethical Imperative for Interactive sessions moderated with Critically Ill Children CLINICAL APPLICATION OF BIOLOGY SYNTHETIC Participant Autonomy and Informed 3-4 starting contributors & audience 16.40 11.40 To be announced shortly Office Hours: Sessions to support Julius Fredens, Postdoc, MRC Lab of Deepak Rajpal, Head, Translational Consent? participation Stephen F. Kingsmore, MD, DSc, new entrepeneurs & showcase start- Molecular Biology Science US, Sanofi President and CEO , Rady Children’s up companies Nicki Tiffin, Associate Professor, Hospital University of Cape Town

17.10 5.30 Networking Break + Exhibition Hall

Updates on the All of Us Research Program 17.30 12.30 Joshua Denny, CEO, All of Us

Such A Lot Of Genome To See… Adapted from Moon River (Henry Mancini, lyrics by Johnny Mercer) 18.00 13.00

Ting Wu, Professor, Department of Genetics, Harvard Medical School GLOBAL KEYNOTES

18.30 13.30 Post-Festival activity – announcement coming soon Time Time GMT EST The Festival of Genomics & Biodata - Agenda Day 3 NICE’s Role in Evaluating Innovative Genomic Technologies 9.00 4.00 Gillian Leng, CEO, NICE

Empowering Citizens’ Health and the Ecosystem with Open Technology 9.30 4.30 Hema Purohit, Director of Government and Public Sector UK/I, Google Cloud, Andrew Miles, Director Healthcare, EMEA, Google Cloud

UK/EUROPE KEYNOTES UK/EUROPE Genetics & Genomics in Drug development 10.00 5.00 Marc Sultan, Global Head, Genetics and Genomics, Roche

10.30 5.30 Poster Presentations + Exhibition Hall

MANAGING BIODATA SINGLE CELL ANALYSIS CLINICAL GENOMICS GENOMICS IN RESEARCH DOWN THE RABBIT HOLE MASTERMIND SESSIONS START-UP ZONE

Sequencing all Eukaryotic Diversity Rare Cell Omics in Clinical Research Multi-Omics Data Integrations in Spatial Transcriptomics for in Britain and Ireland: The Darwin

Early Discovery Neurobiological Studies Tree of Life Project Stefan Kirsch, Group Leader, Interactive sessions moderated with 11.00 6.00 Innovative Molecular Technologies 3-4 starting contributors & audience Emma Laing, Director of Omer Bayraktar, Group Leader, Marcela Uliano da Silva, Senior and Biomarker discovery, Fraunhofer participation Computational Biology, GSK Wellcome Sanger Institute Bioinformatician, Wellcome Sanger ITEM Institute

11.30 6.30 Fuelling the Century of Biology with Single Cell and Spatial Technologies Using Synthetic Biology to Develop Discussion: What's the new frontier Algal Production Platforms for High Sponsor slot available - email for genomics in CTs Omer Bayraktar, Group Leader, Wellcome TaKaRa Bio - Talk title to be Value Compounds 11.40 6.40 [email protected] for Sanger Institute announced shortly details Sandra Smieszek, Head of Genetics, Florian Baumgartner, Senior Product Alison Smith, Professor, University Vanda Pharmaceuticals Manager, Visium Spatial Informatics, 10x

Genomics of Cambridge MASTERMINDS SPATIAL GENOMICS SPATIAL SINGLE CELL ANALYSIS SINGLE CELL Sponsored by 10x Genomics 11.50 6.50 RABBITDOWN THE HOLE

INTEGRATING DIVERSE DATA SETS DIVERSEINTEGRATING DATA Data-Driven External Innovation at a Reconstructing Metabolic Liver Foodomics: Connecting Food Quality and Panel: The Future of Single Cell Biotech Company Zonation Using Spatial Safety to Our Health and Well-Being Interactive sessions moderated with Analysis through the Application of Genomic INTEGRATING GENOMICSINTEGRATING INTO CLINICAL TRIALS Transcriptomics 3-4 starting contributors & audience 12.00 7.00 Technologies Lili Peng, Associate Director, participation Dan Chang, Single Cell Lead, Merck Scientific Ecosystem Analytics Lead, Sebastian Bergling, Computational Marilisa Neri, Investigator, NIBR Olivia McAuliffe, Principal Scientist, External Innovation, Biogen Biologist, Novartis Teagasc Food Research Centre

12.30 7.30 Live Lounge

12.45 7.45 Live Lounge - Hamilton - Talk title to be announced shortly

13.00 8.00 Live Lounge

13.15 8.15 Live Lounge

13.30 8.30 Networking Break + Exhibition Hall

MANAGING BIODATA SINGLE CELL ANALYSIS CLINICAL GENOMICS GENOMICS IN RESEARCH DOWN THE RABBIT HOLE MASTERMIND SESSIONS START-UP ZONE

13.40 8.40 Creating Real-World Knowledge Construction, Application and RNA Transcriptomics to Accelerate Genome-Wide Engineering of Accelerator Single Cell Approaches for CNS Graphs Cataloguing of Polygenic Risk Scores Cancer Research Pathogens Using Synthetic Target Credentialing and Discovery Genomics Interactive sessions moderated with Etzard Stolte, Global Head, Michael Inouye, Principal Francesca Buffa, Professor of Mindy Zhang, Principal Scientist, 3-4 starting contributors & audience 14.00 9.00 Knowledge Management, Pharma Investigator, University of Computational Biology & Cancer Sanjay Vashee, Associate Professor, Karen Spink, Innovation Lead Sanofi participation Technical Development, Roche Cambridge Genomics, University of Oxford J. Craig Venter Institute (Precision Medicine), Innovate UK

14.10 9.10 Semantic Modelling & Knowledge Graph of Biological Data: Challenges Human System Risks in Spaceflight & Opportunities Sponsor slot available - email Sponsor slot available - email Nanostring - Talk title to be Presentations: Sessions to support 14.20 9.20 [email protected] for [email protected] for Erik Antonsen, Assistant Director, announced shortly Nandu Gattu, SVP Pharma Analytics, details details Human System Risk Management, new entrepeneurs & showcase start-

Excelra NASA up companies

MASTERMINDS START-UP ZONE START-UP

Sponsored by Excelra SINGLE CELL ANALYSIS SINGLE CELL

14.30 9.30 POLYGENIC RISK SCORES

DOWN THE RABBITDOWN THE HOLE KNOWLEDGE MANAGEMENT KNOWLEDGE Project MinE: an international whole- Opportunities for Preventive RNA SEQ & TRANSCRIPTOMICS How to Remove Bottlenecks of SC Genomics in Cardiovascular Care RNA in Rare Disease Genomic genome sequencing initiative and effort Talk Title TBA Using Genomics to Achieve Analysis Diagnostics and its Application for in establishing a Bioinformatics & ML- Precision Health for Spaceflight Presentations: Sessions to support Driven approach to study the genetic basis Amit Khera, Associate Director, New Discoveries in COVID19 14.40 9.40 Milos Kostic, Postdoctoral Fellow, Malte Lücken, Postdoc, Institute of new entrepeneurs & showcase start- ALS/MND Precision Medicine Unit, Novartis Institute for BioMedical Jennifer Fogarty, Chief Scientist, Computational Biology, Helmholtz up companies Massachusetts General Hospital, Diana Baralle, Professor, University Research NASA Human Research Centre, NASA Zentrum Munchen Alfredo Iacoangeli, Research Fellow in and Associate Member, Broad of Southampton Bioinformatics, King's College London Institute of MIT and Harvard

15.10 10.10 Poster Presentations + Exhibition Hall

MANAGING BIODATA SINGLE CELL ANALYSIS CLINICAL GENOMICS GENOMICS IN RESEARCH DOWN THE RABBIT HOLE MASTERMIND SESSIONS START-UP ZONE

An Occupational Health Perspective Comprehensive Genomic From Genomics to Therapeutics: on Genetic Information in Human 15.40 10.40 Surveillance of SARS-CoV-2 Single-Cell Dissection of Human Spaceflight Disease Circuitry To be announced shortly To be announced shortly Jeffrey Barrett, Director of SARS-CoV- Rebekah Reed, Assistant Director, 2 Genomics Initiative, Sanger Manolis Kellis, Professor of Human Health and Performance Beyond companion diagnostics - what next 16.00 11.00 Institute Computational Biology, MIT Directorate, NASA for ctDNA liquid biopsy in the NHS? Shark Tank: Sessions to support new

Mark Kroese, Director, PHG Foundation entrepeneurs & showcase start-up Science Driven By Space Biology Rachel Butler, Director, South West companies

Genetic Association Analysis of SARS- Exploring the Dark Genome: Genomic Laboratory Hub MASTERMINDS Omics Data Utilizing NASA’s ZONE START-UP COVID ANALYTICS CoV-2 Infection Implications for Precision Medicine Anca Oniscu, Clinical Lead Molecular 16.10 11.10 GeneLab Platform

DOWN THE RABBITDOWN THE HOLE Pathology, Royal Infirmary of Edinburgh To be announced shortly To be announced shortly Nitzan Rosenfeld, Senior Group Leader,

Jack Kosmiki, Senior Statistical EXPLORING DARK GENOMETHE Tudor Oprea, Professor & Chief, Afshin Beheshti, Bioinformatician Geneticist, Regeneron University of New Mexico School of Cancer Research UK Cambridge Institute, and Principal Investigator, Pharmaceuticals Medicine Laura Blackburn, Head of Science, PHG 16.20 11.20 KBR/NASA Foundation

16.40 11.40 Introduction

16.50 11.50 Sir John Bell, Regius Professor of Medicine, Medical Sciences Division, University of Oxford

Qatar Genome; Shedding light on Middle East Genomics at Scale 17.30 12.30

Said Ismail, Director of Qatar Genome, Qatar Foundation GLOBAL KEYNOTES

18.00 13.00 Eric Topol, Director & Founder, Scripps Research Translational Institute

18.30 13.30 Post-Festival activity – announcement coming soon Time Time GMT EST The Festival of Genomics & Biodata - Agenda Day 4

9.00 4.00 Baroness Nicola Blackwood, Chair, Genomics England

9.30 4.30 Keynote speaker and talk to be announced shortly

10.00 5.00 KEYNOTES UK/EUROPE Keynote speaker and talk to be announced shortly

10.30 5.30 Poster Presentations + Exhibition Hall COVID-19 AI AND THE GENOME GENETIC COUNSELLING GENOMICS IN THE NHS PATIENT DATA MASTERMIND SESSIONS YOUNG SCIENTISTS

Precision Oncology Through Data Genetic Counsellors and Education Insights from COVID-19 Adaptive Data Driven Medicine and the Self- Orchestration, Artificial Intelligence to Support Colleagues with Clinical Educating the NHS Workforce Clinical Trials Learning Healthcare System and Clinical/Preclinical Therapeutics Genetics 11.00 6.00 Ed Miller, Senior Education and Rowena Sharpe, Director of Philip Beer, Genome Scientist, Anguraj Sadanandam, Associate Amanda Pichini, Bristol Genetics Development Officer, Genomics Precision Medicine Trials, University Sanger Institute and NHS Professor, Institute of Cancer Service Education Programme of Birmingham Research Kate Barr, Bristol Genetics Service

Continuing Genomic Research Safely Nursing and its Role in Embedding in the Pandemic - Saliva for Host Sponsor slot available - email Sponsor slot available - email Genomics Sponsor slot available - email Interactive sessions moderated with Genetics Research, SARS-CoV-2 Safe 11.30 6.30 [email protected] for [email protected] for [email protected] for 3-4 starting contributors & audience Samples NHS details details Charlotte Hitchcock, Lead Nurse details participation

Genomics, NHS England DATA PATIENT