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Home , Acetylmethadol, Bemegride, Chlorcyclizine, Cyclopentobarbital, Deoxyepinephrine, Dexetimide

Comprehensive List of Cross-Reactive and Non Cross-Reactive Compounds

Rev.A 10-8-2002 TOX Specificity-Chemical Name Biosite Inc. Page 1

Highest Conc. Tested Conc. Giving Positive TRADE NAME CHEMICAL NAME CLASS (ng/ml) (ng/ml) Sectral Antihypertensive 100,000 Ethanal Acetaldehyde Solvent 10,000,000 Tylenol//APAP Acetaminophen 1,000,000 Acetanilide Analgesic 100,000 Diamox Acetazolamide Diuretic 100,000 Dymelor Antidiabetic 1,000,000 Acetone Solvent 10,000,000 Notensil Acetopromazine Tranquilizer 100,000 Mucomyst Acetyl-l-, N- Mucolytic 100,000 LAAM , l-a- analgesic 100,000 Acetylsalicylic acid Analgesic 1,000,000 Aspirin metabolite Acetylsalicylic acid metab.() Aspirin metabolite 1,000,000 Aspirin metabolite Acetylsalicylic acid metab.(Salicyluric acid) Aspirin metabolite 100,000 Acyclovir Acyloguanosine Antiviral 100,000 Dowacide Q Adamantane, (1-(3-Chloroallyl)-3,5,7-triaza-1-azonia)- Antibacterial 100,000 Gumbaral Adenosylmethionine, S- Anti-inflammatory 100,000 Deracyn 100,000 BZO 1,000 Deracyn metabolite Adinazolam, Desmethyl Benzodiazepine metabolite 100,000 BZO 250 HSA Albumin, Human Protein 5,000,000 Proventil/Ventolin Albuterol Bronchodilator 200,000 Octalene Aldrin Insecticide 100,000 Fosamax Alendronate Bone reabsorption inhibitor 200,000 Diadol 100,000 BAR 150 Zyloprim Allopurinol Antiurolithic 100,000 Nisentil Alphaprodine Narcotic analgesic 100,000 Xanax Benzodiazepine 100,000 BZO 100 Xanax metabolite Alprazolam, 4-Hydroxy- Benzodiazepine metabolite 100,000 BZO 250 Xanax metabolite Alprazolam-glucuronide, a-Hydroxy Benzodiazepine metabolite 5,000 BZO 150 Xanax metabolite Alprazolam, a-Hydroxy- Benzodiazepine metabolite 100,000 BZO 50 Regletin Antiarrhythmic 200,000 Symmetrel Antiviral 100,000 Cylocort Amcinonide Glucocorticoid 100,000 Amikin Amikacin Antibacterial 100,000 Midamor Diuretic 100,000 Survector CNS 100,000

Sources: 1. Merck Index 2.Disposition of Toxic Chemicals in Man 3. Physicians Desk Reference 2000 Rev.A 10-8-2002 TOX Specificity-Chemical Name Biosite Inc. Page 2

Highest Conc. Tested Conc. Giving Positive TRADE NAME CHEMICAL NAME (ng/ml) (ng/ml) Cytradren Aminoglutethimide 100,000 Heptin Aminoheptane, 2- 100,000 Aminopyrine, l- Antipyretic 100,000 Menocil Anorexic 100,000 Menocil metabolite (Euphoria) Aminorex metab.(Methylaminorex, 4-) Anorexic metabolite 100,000 Cordarone Antiarrhythmic 100,000 Solian Amisulpiride 1,000,000 Elavil 100,000 TCA 750 also metabolizes to Elavil metabolite Amitriptyline metabolite(d,l-E-10-Hydroxy-Amitriptyline) Amitriptyline metabolite 100,000 TCA 250 Samiac Ammonium chloride Expectorant 200,000 Amytal Barbiturate 100,000 BAR 100 Ascendin Antidepressant 100,000 Amoxil Antibacterial 100,000 analog Amphetamine analog(Ethylamphetamine, N-) Amphetamine analog 100,000 MeAMP 12,500 Paredrine Amphetamine analog(Hydroxyamphetamine, p-) Amphetamine analog 200,000 AMP 20,000 metabolite Amphetamine metab.(Hippuric acid) Amphetamine metabolite 100,000 Adderall metabolite Amphetamine metab.(Hydroxynorephedrine, p-) Amphetamine metabolite 100,000 Adderall/Dexedrine/Benzadrine Amphetamine, d- Amphetamine 100,000 AMP 1,000 Cydril Amphetamine, l- Amphetamine 100,000 AMP 63,500 Ambisone Amphotericin 100,000 Ampicin Ampicillin Antibacterial 100,000 Laetrile Amygdalin Antineoplastic 1,000,000 Kyanol Aniline Dye 200,000 Analgesine Antipyrine Analgesic 1,000,000 Apocodeine Apocodeine Emetic 100,000 Euporphin Emetic 100,000 Alurate Barbiturate 100,000 BAR 200 Vitamin C Ascorbic acid Vitamin 1,500,000 Nutrasweet Aspartame Sweetener 100,000 Histazol 100,000 THC 20,000 Tenormin Antihypertensive 100,000 Donnatal 100,000 Donnatal metabolite Atropine metab.(Tropic acid) Atropine metabolite 100,000 Donnatal metabolite Atropine metab.(Tropine) Atropine metabolite 2,000,000 OPI 2,000,000

Sources: 1. Merck Index 2.Disposition of Toxic Drugs Chemicals in Man 3. Physicians Desk Reference 2000 Rev.A 10-8-2002 TOX Specificity-Chemical Name Biosite Inc. Page 3

Highest Conc. Tested Conc. Giving Positive TRADE NAME CHEMICAL NAME DRUG CLASS (ng/ml) (ng/ml) Lipitor Atorvastatin Antihyperlipidemic 100,000 Rynatan/Trinalin Antihistaminic 100,000 Imuran Azathioprine Antirheumatic 100,000 Baclon 10,000 Barbitone Barbiturate 100,000 BAR 150 Malonylurea Barbituric acid Manuf. plastics 100,000 BDB BDB(d,l-1-(3,4-Methylenedioxyphenyl)-2-Butanamine) MBDB metabolite 100,000 AMP 2,500 Vanceril Beclomethasone Antiasthmatic 1,000,000 Mikedimide 100,000 Cedad Antidepressant 100,000 Corzide Bendroflumethiazide Diuretic 100,000 Benzidine Benzidine Dye 100,000 Americaine 100,000 Urised Benzoic acid Antifungal 100,000 Tessalon Benzonatate Antitussive 1,000,000 Didrex Anorexic 100,000 also metabolizes to Amphetamine & Proaqua Benzthiazide Diuretic 100,000 Cogentin Benztropine mesylate Anticholinergic 100,000 Phenylmethanol Benzyl Antimicrobial 1,000.00 Bepadin/Vascor 100,000 Berberine Antibacterial 100,000 Celestone Glucocorticoid 100,000 Urecholine 100,000 Bilirubin Bilirubin pigment 2,500 Akineton Anticholinergic 100,000 Dulcolax Bisacodyl Cathartic 100,000 Durazanil Benzodiazepine 100,000 BZO 750 Durazanil metabolite Bromazepam,Hydroxylated cleavage product Benzodiazepine metabolite 100,000 BZO 50,000 Somnurol Bromisovalum 5,000,000 Parlodel Bromoergocryptine, 2-a- Antiparkinsonian 100,000 Dimetane Antihistaminic 100,000 Mappine Bufotenine 100,000 Bumex Diuretic 100,000 Marcaine/Sensorcaine Anesthetic 1,000,000

Sources: 1. Merck Index 2.Disposition of Toxic Drugs Chemicals in Man 3. Physicians Desk Reference 2000 Rev.A 10-8-2002 TOX Specificity-Chemical Name Biosite Inc. Page 4

Highest Conc. Tested Conc. Giving Positive TRADE NAME CHEMICAL NAME DRUG CLASS (ng/ml) (ng/ml) Buprenex Narcotic analgesic 1,000,000 Wellbutrin/Zyban Antidepressant 1,000,000 Wellbutrin/Zyban metabolite Bupropion metabolite Antidepressant 100,000 BuSpar 1,000,000 Butisol Barbiturate 100,000 BAR 200 Butelline Anesthetic 100,000 Fiorinal/Phrenilin Barbiturate 100,000 BAR 150 Soneryl Butethal Barbiturate 100,000 BAR 50 Stadol Narcotic analgesic 100,000 Butanal Butyraldehyde Solvent 100,000 Caffeine Stimulant 2,000,000 Caffeine metabolite Caffeine metab.(Dimethyluric acid, 1,7-) Caffeine metabolite 100,000 Caffeine metabolite Caffeine metab.(Dimethyluric acid, 1,9-) Caffeine metabolite 100,000 Caffeine metabolite Caffeine metab.(Dimethyluric acid, 3,7-) Caffeine metabolite 100,000 Caffeine metabolite Caffeine metab.(Dimethyluric acid, 3,9-) Caffeine metabolite 100,000 Caffeine metabolite Caffeine metab.(Dimethyluric acid, 7,9-) Caffeine metabolite 100,000 Caffeine metabolite Caffeine metab.() Caffeine metabolite 100,000 Camphor Topical Antiseptic 100,000 Phanurane Canrenoic acid Diuretic 100,000 Zostrix Topical analgesic 100,000 Capoten Captopril Antihypertensive 100,000 Carcholin Cholinergic 100,000 Tegretol Anticonvulsant 100,000 THC 10,000 Tegretol metabolite Carbamazepine metab.(Iminostilbene) Carbamazepine metabolite 100,000 Tegretol metabolite Carbamazepine, 10,11-Dihydroxy- Carbamazepine metabolite 100,000 THC 60,000 Tegretol metabolite Carbamazepine-10,11-epoxide Carbamazepine metabolite 100,000 Mycholine Carbamyl-ß-methylcholine chloride Cholinergic 200,000 Carbylderm Carbaryl Pediculocide 100,000 Sinemet Antiparkinsonian 1,000,000 Paraplatin Carboplatin Antineoplastic 100,000 Carbital Sedative 5,000,000 Soma Muscle relaxant 100,000 also metabolizes to Khat/Qat (Catha edulis ) Stimulant 100,000 Ceclor Cefaclor Antibacterial 100,000

Sources: 1. Merck Index 2.Disposition of Toxic Drugs Chemicals in Man 3. Physicians Desk Reference 2000 Rev.A 10-8-2002 TOX Specificity-Chemical Name Biosite Inc. Page 5

Highest Conc. Tested Conc. Giving Positive TRADE NAME CHEMICAL NAME DRUG CLASS (ng/ml) (ng/ml) Duricef Cefadroxil Antibacterial 100,000 Claforan Cefotaxime Antibacterial 100,000 Mefoxin Cefoxitin Antibacterial 100,000 Rocefin Ceftriaxone Antibacterial 100,000 Ceftin Cefuroxime Antibacterial 100,000 Celebrex Anti-imflammatory 200,000 Keflex Cephalexin Antibacterial 100,000 Ceporan Cephaloridine Antibacterial 100,000 Cesporan Cephradine Antibacterial 200,000 Baycol Cerivastatin Antihyperlipidemic 10,000 Somnos hydrate 100,000 Somnos metabolite metab.(Trichloroethanol) Chloral hydrate metabolite 100,000 Dorcalm , a- Sedative 100,000 Chloromycetin Antibacterial 100,000 Trihistan Antihistamine 100,000 Kepone Chlordecon Insecticide 100,000 Librium Benzodiazepine 100,000 BZO 13,000 also metabolizes to & glucuronide Librium metabolite Chlordiazepoxide-desmethyl Chlordiazepoxide metabolite 100,000 BZO 9,000 Trancopal Anxiolytic 100,000 Chloroamphetamine, 4- Chloroamphetamine, 4- Amphetamine 200,000 AMP 2,300 Chlorodiazepam, 4- Chlorodiazepam, 4- Benzodiazepine 100,000 THC 20,000 Aralen Chloroquine Antimalarial 100,000 Steranabol Chlorotestosterone, 4- 17-acetate 100,000 Diuril Chlorothiazide Diuretic 100,000 Merbentul Chlorotrianisene Estrogen 100,000 Chlor-Trimeton Chlorpheniramine Antihistamine 100,000 Thorazine Antipsychotic 100,000 Diabenese Antidiabetic 1,000,000 Taractan Antipsychotic 100,000 Dursban Chlorpyrifos Insecticide 100,000 Combipress Chlorthalidone Diuretic 100,000 Paraflex Muscle relaxant 1,000,000 Cholesterol Emulsifying agent 100,000 Tagamet Antiulcerative 1,000,000

Sources: 1. Merck Index 2.Disposition of Toxic Drugs Chemicals in Man 3. Physicians Desk Reference 2000 Rev.A 10-8-2002 TOX Specificity-Chemical Name Biosite Inc. Page 6

Highest Conc. Tested Conc. Giving Positive TRADE NAME CHEMICAL NAME DRUG CLASS (ng/ml) (ng/ml) Cinchovatine Cinchonidine Antimalarial 100,000 Cinobal Cinoxacin Antibacterial 100,000 Cipro Antibacterial 100,000 Propulsid Peristaltic stimulant 100,000 THC 60,000 Celexa Antidepressant 100,000 Clemanil Antihistamine 100,000 Spiropent Antiasthmatic 100,000 Cleocin Clindamycin Antibacterial 100,000 Frisium Benzodiazepine 100,000 BZO 2,000 Emovate Clobetasone Anti-inflammatory 100,000 Atromid Clofibrate Antihyperlipoproteinic 500,000 Clofilium Clofilium Anti-arrhythmic 100,000 Anafranil 100,000 TCA 12,500 Anafranil metabolite Clomipramine metab.() Clomipramine metabolite 100,000 TCA 75,000 Klonopin Benzodiazepine 100,000 BZO 250 Klonopin metabolite Clonazepam metab.(7-AminoClonazepam) Benzodiazepine metabolite 100,000 BZO 15,000 Catapres Antihypertensive 100,000 Plavix Clopidrogrel Antiplatelet aggregation factor 100,000 Tranxene Benzodiazepine 100,000 BZO 1,600 also metabolizes to Nordiazepam & Oxazepam Cloxapen Cloxacillin Antibacterial 100,000 Clozaril Antipsychotic 100,000 Clozaril metabolite Clozapine metab.() Clozapine metabolite 100,000 THC 40,000 Cocaine Anesthetic 100,000 COC 100,000 Cocaine homolog Cocaine analog(Cocaethylene) Cocaine homolog 100,000 Cocaine analog Cocaine analog(Propylbenzoylecgonine) Benzoylecgonine analog 100,000 Cocaine analog Cocaine analog(Tropacocaine) Cocaine analog 200,000 Cocaine byproduct Cocaine byproduct(Ecgonidine methyl ester) Anesthetic 100,000 Cocaine byproduct Cocaine byproduct(Ecgonine) Anesthetic 100,000 COC 133,000 Cocaine metabolite Cocaine metab.(Benzoylecgonine) Cocaine metabolite 100,000 COC 300 Cocaine metabolite Cocaine metab.(Benzoylnorecgonine) Benzoylecgonine metab. 100,000 COC 100,000 Cocaine metabolite Cocaine metab.(Ecgonine methyl ester) Cocaine metabolite 100,000 Cocaine metabolite Cocaine metab.() Cocaine metabolite 100,000 Codeine Narcotic analgesic 100,000 OPI 300 also metabolizes to

Sources: 1. Merck Index 2.Disposition of Toxic Drugs Chemicals in Man 3. Physicians Desk Reference 2000 Rev.A 10-8-2002 TOX Specificity-Chemical Name Biosite Inc. Page 7

Highest Conc. Tested Conc. Giving Positive TRADE NAME CHEMICAL NAME DRUG CLASS (ng/ml) (ng/ml) Codeine metabolite Codeine metab.() Codeine metabolite 300,000 OPI 300,000 Colbenemid Colchicine Antineoplastic 100,000 Corticosterone Corticosterone Glucocorticoid 100,000 Cortelan Cortisone Glucocorticoid 100,000 Cortelan metabolite Cortisone metab.(Cortolone, ß-) Cortisone metabolite 100,000 Cortelan metabolite Cortisone metab.(Tetrahydrocortisone) Cortisone metabolite 100,000 Scotine , l- Antidepressant 100,000 Creatinine Creatinine Creatine metabolite 5,000,000 Intal Cromolyn Antiasthmatic 100,000 Assugrin Cyclamic acid Non-nutritive sweetener 10,000,000 Cyclazocine Narcotic antagonist 100,000 Marezine 200,000 Flexeril Muscle relaxant 100,000 TCA 1,900 Cyclopal Barbiturate 100,000 BAR 100 Cytoxin Antineoplastic 2,000,000 Sandimmune Cyclosporin A Immunosuppressant 100,000 Doburil Diuretic 100,000 Cyheptamide Cyheptamide Anticonvulsant 100,000 Periactin Antihistamine 1,000,000 Danocrine Danazol Antigonadotropin 100,000 Dantrium Muscle relaxant 100,000 Avlosulfon Dapsone Antibacterial 100,000 THC 40,000 Declinax Debrisoquin Antihypertensive 100,000 Desferal Deferoxamine Chelating agent 100,000 Boldenone Dehydrotestosterone, 1- Androgen 100,000 Delorazepam Benzodiazepine 100,000 BZO 600 Declomycin Demeclocycline Antibacterial 100,000 Demoxepam Demoxepam Benzodiazepine 100,000 BZO 7,700 also metabolizes to Oxazepam Cortexone Deoxycorticosterone Mineralocorticoid 100,000 Epinine Vasoconstrictor 100,000 Norpramine Tricyclic antidepressant 100,000 TCA 1,000 Stiedex Desoximetasone Anti-inflammatory 100,000 Decadron Anti-inflammatory 100,000 Tremblex Anticholinergic 100,000

Sources: 1. Merck Index 2.Disposition of Toxic Drugs Chemicals in Man 3. Physicians Desk Reference 2000 Rev.A 10-8-2002 TOX Specificity-Chemical Name Biosite Inc. Page 8

Highest Conc. Tested Conc. Giving Positive TRADE NAME CHEMICAL NAME DRUG CLASS (ng/ml) (ng/ml) Romilar Antitussive/ 5,000,000 OPI 5,000,000 Romilar metabolite Dextromethorphan metab.(,d-) Dextromethorphan metab. 100,000 Romilar metabolite Dextromethorphan metab.(Hydroxymorphinan, 3-) Dextromethorphan metab. 100,000 Romilar metabolite Dextromethorphan metab.(Methoxymorphinan, 3-) Dextromethorphan metab. 100,000 Diacetylmorphine Narcotic 100,000 OPI 300 also metabolizes to Morphine Heroin byproduct Diacetylmorphine byproduct(Acetylcodeine, 6-) Opiate 100,000 OPI 250 Heroin metabolite Diacetylmorphine metab.(Acetylmorphine, 6- /6-MAM ) Narcotic Opiate 100,000 OPI 300 Valium Benzodiazepine 100,000 BZO 200 also metabolizes to Nordiazepam,Oxazepam & Spectracide Diazinon Insecticide 100,000 Hyperstat Antihypertensive 100,000 Nupercaine Dibucaine Anesthetic 1,000,000 THC 100,000 Welldorm/Midrin Sedative 100,000 Methylene chloride Solvent 500,000 Daranide Dichlorphenamide Carbonic Anhydrase Inhibitor 100,000 Voltaren Anti-inflammatory 1,000,000 Melitoxin Dicumarol Anticoagulant 100,000 Bentyl Dicyclomine Anticholinergic 100,000 HEOD Insecticide 100,000 Imuthiol Diethyldithiocarbamic acid Chelating agent 100,000 Tenuate Diethylpropion Anorexic 100,000 also metabolizes to Maxiflor/Psorcon Diflorasone Anti-inflammatory 100,000 Nerisona Diflucortolone Anti-inflammatory 100,000 Dolobid Analgesic 100,000 Digitalis Digitoxin Cardiotonic 100,000 Lanoxin Digoxin Cardiotonic 100,000 Synalgos Narcotic analgesic 300,000 OPI 250 Cardizem/Tiazac Antianginal/Antiarrhythmic 1,000,000 Drammamine Antiemetic 100,000 BAL Chelating agent 100,000 DOB Dimethoxy-4-bromoamphetamine, 2,5- 5-HT- 100,000 DOM Dimethoxy-4-methylamphetamine, 2,5- 5-HT-agonist 100,000 DMSO Dimethyl sulfoxide Anti-inflammatory 10,000,000

Sources: 1. Merck Index 2.Disposition of Toxic Drugs Chemicals in Man 3. Physicians Desk Reference 2000 Rev.A 10-8-2002 TOX Specificity-Chemical Name Biosite Inc. Page 9

Highest Conc. Tested Conc. Giving Positive TRADE NAME CHEMICAL NAME DRUG CLASS (ng/ml) (ng/ml) DMT Dimethyltryptamine Hallucinogen 100,000 DMT metabolite Dimethyltryptamine metab.(Indole-3-) Dimethyltryptamine metab. 100,000 Benadryl Antihistamine/ Sedative 1,000,000 Lomotil Antidiarrheal 100,000 Persantine Dipyridamole Coronary vasodilator 100,000 Palerol Dipyrone Analgesic 100,000 Reglone Diquat Herbicide 10,000 Norpace Antiarrhythmic 200,000 Antabuse Disulfiram Alcohol deterrent 100,000 Dobutrex Cardiotonic 100,000 Motilium Antiemetic 100,000 Aricept Acetylcholinesterase inhibitor 200,000 Levodopa Dopa, l- Antiparkinsonian 100,000 Levodopa metabolite Dopa, l- metab. (Homovanillic acid) l-Dopa metabolite 200,000 Levodopa metabolite Dopa, l metab.(Methoxy-4-hydroxyphenethylamine, 3-) l-Dopa metabolite 100,000 Levodopa metabolite Dopa, l metab.(3-o-Methyldopamine) l-Dopa metabolite 100,000 Levodopa metabolite Dopa, l-3-o-Methyl/, 3-Methoxy-l- l-Dopa metabolite 100,000 Inovan Cardiotonic 100,000 Inovan metabolite Dopamine metab.(Dihydroxyphenylacetic acid, 3,4-) Dopamine metabolite 100,000 Inovan metabolite Dopamine metab.(Methoxy-3-hydroxyphenethylamine, 4-) Dopamine metabolite 100,000 Prothiaden Dothiepin Tricyclic Antidepressant 100,000 TCA 1,000 Dopram Respiratory stimulant 100,000 Sinequan Tricyclic antidepressant 100,000 TCA 1,300 Sinequan metabolite Doxepin metab.() Doxepin metabolite 100,000 TCA 1,500 Vibramycin Doxycycline Antibacterial 1,000,000 Unisom Antihistamine/ Sedative 100,000 Dridol Antipsychotic 100,000 Lufylin Dyphylline Bronchodilator 100,000 Enlon Edrophonium Cholinergic 100,000 Arsemetine Emetine Antiamebic 100,000 Vasotec Enalapril Antihypertensive 100,000 Hexadrin Endrin Insecticide 100,000 Ethrane Anesthetic 1,000,000 Ephedrine, d- Adrenergic 10,000,000 Ephedrine metabolite Ephedrine, d- metab.(Norephedrine, d-) Ephedrine, d- metabolite 100,000

Sources: 1. Merck Index 2.Disposition of Toxic Drugs Chemicals in Man 3. Physicians Desk Reference 2000 Rev.A 10-8-2002 TOX Specificity-Chemical Name Biosite Inc. Page 10

Highest Conc. Tested Conc. Giving Positive TRADE NAME CHEMICAL NAME DRUG CLASS (ng/ml) (ng/ml) Ephedrine Ephedrine, l- Bronchodilator 10,000,000 MeAMP 400,000 also metabolizes to Phenylpropanolamine Adrenalin metabolite Epinephrine metab.() Epinephrine metabolite 300,000 Adrenalin metabolite Epinephrine metab.() Epinephrine metabolite 100,000 Adrenalin metabolite Epinephrine metab.(Vanillylmandelic acid, d,l-) Epinephrine metabolite 200,000 Adrenalin Epinephrine, l- Adrenergic 1,000,000 Isotestosterone Epitestosterone Androgen 100,000 Ergomar Antimigraine 1,000,000 Erythrocin , l- Antibacterial 100,000 ProSom Benzodiazepine 100,000 BZO 300 Estrace Estradiol,17 ß- Estrogen 100,000 Synapause Estriol Estrogen 100,000 Estrol Estrone Estrogen 100,000 E-3-G Estrone-3-glucuronide (E-3-G) Estrogen 100,000 Ogen Estrone-3-sulfate Estrogen 100,000 Edecrin Ethacrynic acid Diuretic 100,000 Myambutol Ethambutol Antibacterial 100,000 Emivan Ethamivan Central stimulant 100,000 Alcohol Antiseptic 20,000,000 Placidyl Sedative 100,000 Valmid Sedative 100,000 Birth Control Pills Ethinyl estradiol Estrogen/contraceptive 100,000 Dibutil Ethopropazine Antiparkinsonian 100,000 Zarontin Anticonvulsant 1,000,000 BAR 750,000 Peganone Anticonvulsant 100,000 glycol Ethylene glycol Solvent 10,000,000 EDTA Ethylenediaminetetraacetic acid Chelating agent 100,000 Dionin Antitussive/Opiate 100,000 OPI 300 Lodine Anti-inflammatory 100,000 THC 50,000 VePesid Etoposide Antineoplastic 100,000 Pepcid Anti-ulcerative 100,000 Euvitol Fencamfamine Central stimulant 1,000,000 Pondimin Anorexic 100,000 MeAMP 40,000 Pondimin metabolite Fenfluramine metab.(Trifluoromethylbenzoic acid, m-) Fenfluramine metabolite 100,000 Nalfon Anti-inflammatory 100,000

Sources: 1. Merck Index 2.Disposition of Toxic Drugs Chemicals in Man 3. Physicians Desk Reference 2000 Rev.A 10-8-2002 TOX Specificity-Chemical Name Biosite Inc. Page 11

Highest Conc. Tested Conc. Giving Positive TRADE NAME CHEMICAL NAME DRUG CLASS (ng/ml) (ng/ml) Antiobes Anorexic 100,000 Sublimaze Narcotic analgesic 100,000 Sublimaze metabolite Fentanyl metab.(Despropionyl fentanyl) Fentanyl metabolite 10,000 Sublimaze metabolite Fentanyl metab.(Norfentanyl) Fentanyl metabolite 10,000 Feosol Ferrous sulfate Hematinic 10,000,000 Allegra Antihistamine 100,000 Diflucan Fluconazole Antifungal 100,000 Paraflu Anti-inflammatory 100,000 Romazicon Benzodiazepine antagonist 100,000 Romazicon metabolite Flumazenil metabolite Flumazenil metabolite 100,000 Nasalide Glucocorticoid 100,000 Rohypnol Benzodiazepine 100,000 BZO 150 Rohypnol metabolite Flunitrazepam metab.(7-Aminoflunitrazepam) Benzodiazepine 100,000 BZO 7,500 Fluothane Anesthetic 500,000 Prozac Antidepressant 100,000 Prozac metabolite Fluoxetine metab.(Norfluoxetine) Prozac metabolite 100,000 Testoral Fluoxymesterone Androgen 100,000 Fluanxol Flupenthixol Antipsychotic 100,000 Prolixin Antipsychotic 100,000 Cordran Flurandrenolide Glucocorticoid 100,000 Dalmane Benzodiazepine 100,000 BZO 100 Dalmane metabolite Flurazepam metab.(Desalkylflurazepam) Benzodiazepine 100,000 BZO 200 Dalmane metabolite Flurazepam metab.(N-Hydroxyethyl Flurazepam) Flurazepam metabolite 100,000 BZO 50 Froben Anti-inflammatory 1,000,000 Redeptin Neuroleptic 100,000 Luvox Antidepressant 100,000 Foliamin Folic acid Hematopoietic vitamin 1,000,000 Formalin Antiseptic 10,000,000 Monopril Fosinopril ACE inhibitor 100,000 Lasix Diuretic 100,000 Neurontin Anticonvulsant 100,000 GHB Gamma-Hydroxybutyric acid GABA metabolite 1,000,000 Tequin Gatifloxacin Antibiotic 5,000,000 Lopid Gemfibrozil Antihyperlipoproteinemic 100,000 Garamycin Gentamicin Antibacterial 100,000

Sources: 1. Merck Index 2.Disposition of Toxic Drugs Chemicals in Man 3. Physicians Desk Reference 2000 Rev.A 10-8-2002 TOX Specificity-Chemical Name Biosite Inc. Page 12

Highest Conc. Tested Conc. Giving Positive TRADE NAME CHEMICAL NAME DRUG CLASS (ng/ml) (ng/ml) Gentisod Gentisic acid Analgesic 100,000 Glucotrol Antidiabetic 100,000 Dextrose Glucose Sugar 20,000,000 Doriden , d,l- Sedative 100,000 BAR 50,000 DiaBeta Glyburide (Glybenclamide) Antidiabetic 100,000 Grisactin Glycopyrrolate Anticholinergic 100,000 Grifulvin Griseofulvin Antifungal 100,000 Robitussin Guaiphenesin/Guaiacol glyceryl ether Expectorant 1,000,000 Wytensin Antihypertensive 100,000 THC 20,000 Ismelin Antihypertensive 200,000 Paxipam Benzodiazepine 100,000 BZO 100 also metabolizes to Nordiazepam Halog Halcinonide Anti-inflammatory 100,000 Haldol Antidyskinetic 100,000 Haldol metabolite Haloperidol metabolite I Haloperidol metabolite 100,000 Haldol metabolite Haloperidol metabolite II Haloperidol metabolite 100,000 Haldol metabolite Haloperidol metabolite III Haloperidol metabolite 100,000 Heme Hemoglogin (Lysed Red Blood Cells) Protein 1,200,000 Heparin Heparin Anticoagulant 100,000 Bunt-cure Hexachlorobenzene Fungicide 100,000 Phisohex Hexachlorophene Anti-infective 100,000 Vegolysen Antihypertensive 100,000 Hexanal Barbiturate 100,000 Peremine Diagnostic aid 1,000,000 Peremine metabolite Histamine metab.(-4-acetic acid) Histamine metabolite 200,000 Peremine metabolite Histamine metab.(Methyl histamine, 1-) Histamine metabolite 100,000 Homapin Anticholinergic 100,000 Apresoline Antihypertensive 100,000 /Goldenseal Hydrastine Diuretic 100,000 HCTZ/Hyzaar Hydrochlorothiazide Diuretic 100,000 Vicodin Antitussive/Narcotic analgesic 100,000 OPI 1,700 also metabolizes to Dihydrocodeine & Cortazac Glucocorticoid 100,000 Cortazac metabolite Hydrocortisone metab.(Cortol, ß-) Hydrocortisone metabolite 100,000 Diucardin Hydroflumethiazide Diuretic 100,000

Sources: 1. Merck Index 2.Disposition of Toxic Drugs Chemicals in Man 3. Physicians Desk Reference 2000 Rev.A 10-8-2002 TOX Specificity-Chemical Name Biosite Inc. Page 13

Highest Conc. Tested Conc. Giving Positive TRADE NAME CHEMICAL NAME DRUG CLASS (ng/ml) (ng/ml) Dilaudid Hydromorphone Narcotic analgesic 100,000 OPI 1,700 Vitamin B-12 Hematopoietic vitamin 100,000 Atarax Antihistamine/ Sedative 100,000 also metabolizes to Donnatal , l- Anticholinergic 100,000 Motrin Anti-inflammatory 1,000,000 Validex Vasodilator 100,000 Tofranil Tricyclic antidepressant 100,000 TCA 600 also metabolizes to Desipramine Lozol Indapamide Diuretic 100,000 Indole-3-butyric acid Indole-3-butyric acid Plant growth factor 100,000 Indocin Indomethacin Analgesic 100,000 Humulin Insulin Antidiabetic 100,000 Atrovent Ipratropium Bronchodilator 100,000 Euphozid Antidepressant 100,000 Midrin Adrenergic 100,000 MeAMP 100,000 Neoxin Antibacterial 100,000 Tyrimide Anticholinergic 100,000 Isopropanol Isopropanol Antiseptic 5,000,000 Norisodrine Isoproterenol, d,l- Bronchodilator 100,000 Isordil Isosorbide Diuretic 100,000 Dilavase Vasodilator 100,000 Lomir Antianginal 100,000 THC 90,000 Kantrex Kanamycin Antibacterial 100,000 Ketalar Anesthetic 100,000 Serefrex Antihypertensive 100,000 Nizoral Antifungal 100,000 Orudis Analgesic 1,000,000 Toradol tromethamine Analgesic 100,000 Trandate/Normodyne Antihypertensive 1,000,000 Trandate metabolite Labetalol metab.(3-Amino-1-Phenylbutane) Labetalol metabolite 1,000,000 Previcid Lansoprazole Anti-ulcerative 100,000 Lorfan Narcotic antagonist 100,000 Levasole/Ergamisol Antiparasitic 1,000,000 Levaquin Antibiotic 2,500,000 OPI 2,500,000

Sources: 1. Merck Index 2.Disposition of Toxic Drugs Chemicals in Man 3. Physicians Desk Reference 2000 Rev.A 10-8-2002 TOX Specificity-Chemical Name Biosite Inc. Page 14

Highest Conc. Tested Conc. Giving Positive TRADE NAME CHEMICAL NAME DRUG CLASS (ng/ml) (ng/ml) Levo-Dromoran (Dextrorphan, l-) Narcotic analgesic 100,000 OPI 25,000 MEGX metab.( Monoethylglycinexylidide) Lidocaine metabolite 100,000 Xylocaine Lidocaine Anesthetic 100,000 Aparasin Pediculicide 100,000 Zestril/Prinivil Lisinopril Antihypertensive 100,000 Dopergin Antimigraine 100,000 Eskalith carbonate Antimanic 200,000 Imodium Antidiarrheal 100,000 Claritin Antihistamine 200,000 Ativan Benzodiazepine 100,000 BZO 200 Ativan metabolite Lorazepam glucuronide Benzodiazepine metabolite 10,000 BZO 300 Lorivox Lorcainide Antiarrythmic 100,000 Ergocalm Benzodiazepine 100,000 BZO 250 Loxitane Anxiolytic 100,000 LSD diethylamide Psychomimetic 2,500 LSD precursor-Lysergic acid Lysergic acid, d- LSD precursor 100,000 Epsom salts sulfate Anticonvulsant 1,000,000 Organoderm Malathion Insecticide 1,000,000 Ludiomil Antidepressant 100,000 Sanorex Anorexic 200,000 MBDB MBDB(d,l-Methyl-1(3,4-Methylenedioxyphenyl)2-Butanamine) MDMA analog 100,000 MeAMP 800 also metabolizes to BDB MDA MDA (3,4-Methylenedioxyamphetamine) Amphetamine analog 100,000 AMP 3,700 MDA, N-Hydroxy- MDA, N-Hydroxy- MDA analog 100,000 Eve MDEA (3,4-Methylenedioxethylamphetamine) Amphetamine analog 100,000 MeAMP 4,600 Ecstasy MDMA (3,4-Methylenedioxymethamphetamine) Amphetamine analog 100,000 MeAMP 1,500 MDPA MDPA / Methylenedioxypropylamphetamine, 3,4- Amphetamine analog 100,000 Vermicidin Mebendazole Anthelmintic 100,000 Antivert Antiemetic 100,000 Meclomen Anti-inflammatory 100,000 Nobrium Benzodiazepine 100,000 BZO 32,000 also metabolizes to Diazepam, Nordiazepam, Oxazepam & Temazepam Depo-Provera Medroxyprogesterone Contraceptive 100,000 Ponstel Anti-inflammatory 100,000 Melanin Melanin Skin pigment 100,000

Sources: 1. Merck Index 2.Disposition of Toxic Drugs Chemicals in Man 3. Physicians Desk Reference 2000 Rev.A 10-8-2002 TOX Specificity-Chemical Name Biosite Inc. Page 15

Highest Conc. Tested Conc. Giving Positive TRADE NAME CHEMICAL NAME DRUG CLASS (ng/ml) (ng/ml) Bevitamel Pineal hormone 100,000 Eunerpan Antipsychotic 100,000 Alkeran Melphalan Antineoplastic 100,000 Akatinol Muscle relaxant 100,000 Menthol Flavoring 100,000 Demerol/ Meperidine Narcotic analgesic 100,000 Demerol/Pethidine metabolite Meperidine metab.(Normeperidine) Meperidine metabolite 100,000 Myanesin Muscle relaxant 100,000 Vialin Adrenergic 300,000 MeAMP 30,000 also metabolizes to Mesantoin Anticonvulsant 100,000 Mesantoin metabolite Mephenytoin metab.(Hydroxymephenytoin, 4-) Mephenytoin metabolite 100,000 Mebaral Mephobarbital Barbiturate 100,000 BAR 20,000 also metabolizes to Polocaine Anesthetic 1,000,000 Equanil/Miltown/Equagesic Meprobamate Sedative 100,000 Leukerin Mercaptopurine, 6- Antineoplastic 100,000 Mersalin Mersalyl acid Diuretic 100,000 Hallucinogen 100,000 Serentil Antipsychotic 1,000,000 Alupent Metaproterenol Bronchodilator 200,000 Aramine Adrenergic 500,000 Contralac inhibitor 100,000 Glucophage Metformin(Dimethylbiguanide, 1,1-) Antidiabetic 100,000 Dolophine metabolite primary metabolite(EDDP) Methadone metabolite 100,000 Dolophine metabolite Methadone secondary metabolite(EMDP) Methadone metabolite 100,000 Dolophine Methadone, dl- Narcotic analgesic 100,000 Dolophine isomer Methadone, d- Methadone isomer 100,000 Levodone Methadone, l- Narcotic analgesic 100,000 Desoxyn metabolite Methamphetamine metab.(Hydroxy methamphetamine, p-) Methamphetamine metabolite 100,000 MeAMP 2,500 Desoxyn/Speed/Ice/Crystal Methamphetamine, d- Amphetamine 100,000 MeAMP 1,000 also metabolizes to Amphetamine, d- Vicks Inhaler Methamphetamine, l- OTC 100,000 MeAMP 30,500 Dianabol Methandrostenolone Androgen 100,000 Wood alcohol Solvent 10,000,000

Sources: 1. Merck Index 2.Disposition of Toxic Drugs Chemicals in Man 3. Physicians Desk Reference 2000 Rev.A 10-8-2002 TOX Specificity-Chemical Name Biosite Inc. Page 16

Highest Conc. Tested Conc. Giving Positive TRADE NAME CHEMICAL NAME DRUG CLASS (ng/ml) (ng/ml) Histadyl Antihistamine/Sedative 1,000,000 Quaalude Hypnotic 100,000 Gemonil Anticonvulsant/Barbiturate 1,000,000 BAR 1,400 also metabolizes to Barbital Neptazane Methazolamide Diuretic 100,000 Urised/Urex/Uriquid Methenamine Antibacterial 200,000 Methenolone Methenolone Anabolic 100,000 Robaxin Relaxant 1,000,000 Brevital Anesthetic/Barbiturate 1,000,000 Rheumatrex Methotrexate Antineoplastic 2,000,000 Levoprome Methotrimeprazine Analgesic 100,000 Vasylox Adrenergic 100,000 Metofane Anesthetic 1,000,000 Proasma Bronchodilator 100,000 Mexamin Methoxytryptamine, 5- Hypnotic potentiator 100,000 Celontin Methsuximide Anticonvulsant 100,000 Celontin metabolite Methsuximide metab.(Normethsuximide) Methsuximide metabolite 100,000 Oil of wintergreen 5,000,000 Methylamino-propiophenone, 2- Amphetamine-like 100,000 Aldomet/Dopamet Antihypertensive 100,000 Methylene blue Antimethemoglobinemic 10,000 Metheph Methylephedrine, N-(1R,2S)-(-) Analeptic 100,000 Metheph Methylephedrine, N-(1S,2R)-(+) Analeptic 100,000 Levonordefrin Methylnorepinephrine, (-) a- Vasoconstrictor 100,000 Ritalin Stimulant 1,000,000 Medrol Methylprednisolone, 6-a- Glucocorticoid 100,000 Metheph Methylpseudoephedrine, N-(1R,2R)-(-) Analeptic 100,000 Metheph Methylpseudoephedrine, N-(1S,2S)-(+) Analeptic 100,000 Estratest/Testred Methyltestosterone, 17-a- Androgen 100,000 Noludar Sedative 100,000 Arresten Meticrane Diuretic 100,000 Reglan Peristaltic stimulant 1,000,000 Zaroxolyn Metolazone Diuretic 100,000 Lopressor , d,l- Antihypertensive 100,000 Flagyl Metronidazole Antiprotazoal 1,000,000

Sources: 1. Merck Index 2.Disposition of Toxic Drugs Chemicals in Man 3. Physicians Desk Reference 2000 Rev.A 10-8-2002 TOX Specificity-Chemical Name Biosite Inc. Page 17

Highest Conc. Tested Conc. Giving Positive TRADE NAME CHEMICAL NAME DRUG CLASS (ng/ml) (ng/ml) Mexitil Antiarrhythmic 100,000 Norval Antidepressant 100,000 Versed Benzodiazepine 100,000 BZO 300 Versed metabolite Midazolam metab.(a-Hydroxymidazolam) Benzodiazepine metabolite 10,000 BZO 200 Primacor Milrinone Cardiotonic 100,000 Cantor Psychotropic 100,000 Rogaine Antialopecia agent 100,000 Remeron Mirtazepine Antipsychotic 1,000,000 Singulair Montelukast Anti-asthmatic 100,000 Morphine/Roxicet Morphine Narcotic analgesic 100,000 OPI 300 Morphine metabolite Morphine 3-ß-glucuronide Morphine metabolite 100,000 OPI 450 Morphine metabolite Morphine metab.() Narcotic analgesic 300,000 OPI 200,000 Relafen Anti-inflammatory 100,000 Corzide Antihypertensive 200,000 Nafcil Nafcillin Antibacterial 100,000 Nubain Narcotic analgesic 1,000,000 Negram Nalidixic acid Antibacterial 1,000,000 Revex Narcotic antagonist 100,000 Lethidrone Narcotic antagonist 300,000 OPI 1,900 Narcan Narcotic antagonist 300,000 OPI 200,000 ReVia Narcotic antagonist 100,000 Naphcon Adrenergic 100,000 Aleve/Naprosyn Anti-inflammatory 100,000 Serzone Nefazadone Antidepressant 100,000 Serzone metabolite Nefazadone metab.(, 1-(3-chlorophenyl)-) Serzone metabolite 100,000 Ajan Antidepressant 100,000 Neomin Antibacterial 200,000 Niamid Antidepressant 100,000 Nicarpin Antianginal 100,000 Vitamin B3 / Vitamin ( cofactor) 100,000 Nicotine Vasoconstrictor 1,000,000 THC 200,000 Nicotine metabolite Nicotine metab.(Cotinine, l-) Antidepressant 100,000 Vitamin B3 Nicotinic acid/Niacin Vitamin (enzyme cofactor) 1,000,000 Vitamin B3 metabolite Nicotinic acid metab.(Hydroxynicotinic acid, 6-) Vitamin metabolite 200,000 Procardia/Adalat Antianginal 100,000

Sources: 1. Merck Index 2.Disposition of Toxic Drugs Chemicals in Man 3. Physicians Desk Reference 2000 Rev.A 10-8-2002 TOX Specificity-Chemical Name Biosite Inc. Page 18

Highest Conc. Tested Conc. Giving Positive TRADE NAME CHEMICAL NAME DRUG CLASS (ng/ml) (ng/ml) Nikardin Stimulant 100,000 Mogadon Benzodiazepine 100,000 BZO 2,600 Mogadon metabolite Nitrazepam metab.(2-Amino-5-Nitrobenzophenone) Benzodiazepine metabolite 100,000 Nidrel Antihypertensive 100,000 Furadantin Nitrofurantoin Antibacterial 100,000 Angibid Nitroglycerin Antianginal 100,000 Axid Antiulcerative 100,000 Merital Antidepressant 100,000 Nordaz Nordiazepam Benzodiazepine 100,000 BZO 700 also metabolizes to Oxazepam Adrenor metabolite metab(d,l-Hydroxy-3-methoxyphenyl glycol4-) Norepinephrine metabolite 200,000 Adrenor metabolite Norepinephrine metab.(d,l-Dihydroxymandelic acid,3,4-) Norepinephrine metabolite 200,000 Adrenor Norepinephrine, l- Adrenergic 1,000,000 Adrenor metabolite Norepineprine metab.(d,l-Dihydroxyphenylglycol,3,4-) Norepinephrine metabolite 200,000 Nilevar Norethandrolone Androgen 100,000 Birth Control Pills Norethindrone /Contraceptive 100,000 Noroxcin Norfloxacin Antibacterial 100,000 Normetazocine Normetazocine metabolite 100,000 Nandrolone Nortestosterone, 19- Anabolic Steroid 100,000 Pamelor/Aventyl Nortriptyline Tricyclic antidepressant 100,000 TCA 1,100 Pamelor/Aventyl metabolite Nortriptyline metabolite (+/- E-10-hydroxylated) Nortriptyline metabolite 100,000 TCA 750 Pamelor/Aventyl metabolite Nortriptyline metabolite (+/- Z-10-hydroxylated) Nortriptyline metabolite 100,000 TCA 5,000 Narcosine Antitussive 100,000 Arlidin Nylidrin Vasodilator 100,000 Norden Adrenergic 100,000 Floxin Antibiotic 2,500,000 Zyprexa Antipsychotic 100,000 Prilosec Omeprazole Anti-ulcerative 100,000 Orotyl Orotic acid Uricosuric 100,000 Norflex Antihistamine 1,000,000 Astrobain Ouabain Cardiotonic 100,000 Oxalic acid Oxalic acid Hemostatic agent 10,000,000 Oxandrolone Oxandrolone Androgen 100,000 Daypro Anti-inflammatory 100,000 Serax Oxazepam Benzodiazepine 100,000 BZO 3,500

Sources: 1. Merck Index 2.Disposition of Toxic Drugs Chemicals in Man 3. Physicians Desk Reference 2000 Rev.A 10-8-2002 TOX Specificity-Chemical Name Biosite Inc. Page 19

Highest Conc. Tested Conc. Giving Positive TRADE NAME CHEMICAL NAME DRUG CLASS (ng/ml) (ng/ml) Serax metabolite Oxazepam glucuronide Benzodiazepine metabolite 10,000 BZO 1,100 Serenal Benzodiazepine 100,000 Urinox Antibacterial 100,000 Laracor Antihypertensive 100,000 Ditropan Anticholinergic 100,000 Percodan/Oxycontin Narcotic analgesic 100,000 OPI 23,000 Oxilin Adrenergic 100,000 Anadrol Oxymetholone Androgen 100,000 Numorphan Narcotic analgesic 100,000 OPI 41,000 Numorphan metabolite Oxymorphone metab.() Oxymorphone metabolite 300,000 Tandearil Anti-inflammatory 100,000 Oxycyclin Oxytetracycline Antibacterial 100,000 Pitocin Oxytocin Pituitary Hormone 100,000 Pavulon Pancuronium Muscle relaxant 100,000 Protonix Pantoprazole Anti-ulcerative 1,000,000 THC 750,000 Pavabid Relaxant 100,000 PABA para-Aminobenzoic acid Ultraviolet screen 200,000 Paral Sedative 1,000,000 Paradione Anticonvulsant 100,000 para-Nitrophenol para-Nitrophenol Dye 100,000 Gramoxone Paraquat Herbicide 100,000 Aphamite Parathion Insecticide 1,000,000 Eutonyl Antihypertensive 100,000 Paxil Antidepressant 100,000 THC 20,000 PCP analog PCA (1-Phenylcyclohexylamine) PCP analog 100,000 PCP analog PCC (1-Piperidinocyclohexane Carbonitrile) PCP analog 100,000 PCP analog PCE (n-Ethyl-1-Phenylcyclohexylamine) PCP analog 100,000 PCP 5,000 PCP/Angel dust PCP/ PCP 100,000 PCP 25 PCP metabolite PCP metab.(Hydroxy PCP, 4-) PCP metabolite 100,000 PCP 25,000 PCP analog PCPy (1-(1-Phenylcyclohexyl)-pyrrolidine) PCP analog 100,000 PCP 400 Pondex/Cylert CNS stimulant 100,000 Cuprimine Penicillamine Chelating agent 100,000 Bicillin G Antibacterial 100,000 Bicillin Penicillin V Antibacterial 100,000 Santobrite Pentachlorophenol Insecticide 100,000

Sources: 1. Merck Index 2.Disposition of Toxic Drugs Chemicals in Man 3. Physicians Desk Reference 2000 Rev.A 10-8-2002 TOX Specificity-Chemical Name Biosite Inc. Page 20

Highest Conc. Tested Conc. Giving Positive TRADE NAME CHEMICAL NAME DRUG CLASS (ng/ml) (ng/ml) Talwin Narcotic analgesic 300,000 Nembutal Barbiturate 100,000 BAR 300 Trental Pentoxifylline Vasodilator 100,000 Cardizole Pentylenetetrazole Central stimulant 100,000 Taxilan Antipsychotic 100,000 Permax Antiparkinsonian 100,000 Trilafon Antipsychotic 100,000 APC tablets Analgesic 100,000 also metabolizes to Acetaminophen Phenallylmal Barbiturate 100,000 BAR 100 Pyridium Analgesic 100,000 Bontril Anorexic 100,000 also metabolizes to Nardil Antidepressant 1,000,000 PEA , B- Amphetamine analog 1,000,000 AMP 40,000 Dibotin Phenformin Antidiabetic 100,000 Poly-Histine Antihistamine 100,000 Preludin Phenmetrazine Anorexic 100,000 MeAMP 90,000 Luminal metabolite Phenobarbital metab.(Hydroxyphenobarbital, p-) Barbiturate 100,000 BAR 350 Luminal Phenobarbital Barbiturate 100,000 BAR 150 Carbolic acid Topical Antiseptic 100,000 Chocolax Phenolphthalein 100,000 Phenoverm Anthelmintic 100,000 Dibenzyline Antihypertensive 100,000 THC 25,000 Milontin Anticonvulsant 500,000 Adipex-P/Fastin/Ionamin Phentermine Anorexic 100,000 Rogitine Antihypertensive 100,000 Phenylacetone Phenylacetone Organic synthesis 100,000 , d,l- Phenylalanine, dl- Amino Acid 100,000 Butazolidin Anti-inflammatory 100,000 Phenylenediamine, m- Phenylenediamine, m- Dye 200,000 Orsin Phenylenediamine, p- Dye 200,000 Neo- Decongestant 100,000 Dexatrim Phenylpropanolamine(Norephedrine, l-) Decongestant 1,000,000 Poly-Histine Antihistamine 1,000,000

Sources: 1. Merck Index 2.Disposition of Toxic Drugs Chemicals in Man 3. Physicians Desk Reference 2000 Rev.A 10-8-2002 TOX Specificity-Chemical Name Biosite Inc. Page 21

Highest Conc. Tested Conc. Giving Positive TRADE NAME CHEMICAL NAME DRUG CLASS (ng/ml) (ng/ml) Dilantin (Diphenylhydantoin, 5,5- ) Anticonvulsant 100,000 Dilantin metabolite Phenytoin metab(p-Hydroxyphenyl)-5-phenylhydantoin,d,l 5-) Anticonvulsant metabolite 100,000 Dilantin metabolite Phenytoin metab.(m-Hydroxyphenyl)-5-phenylhydantoin, 5-) Anticonvulsant metabolite 100,000 Tuxi Antitussive/Opiate 100,000 OPI 400 Neantine Phthalic acid Organic solvent 100,000 THC 25,000 Vitamin K1 Phylloquinone Prothrombogenic vitamin 100,000 Antilirium Cholinergic 100,000 Antilirium metabolite Physostigmine metab. () Analgesic 100,000 Cocculin CNS stimulant 100,000 Akarpine/Salagen Antiglaucoma 100,000 Opiran Antipsychotic 100,000 Pindac Antihypertensive 100,000 Visken Antihypertensive 100,000 metabolite Pipecolic acid, l- Lysine metabolite 100,000 Pipram Pipemidic acid Antibacterial 1,000,000 Pirodal Piromidic acid Antibacterial 1,000,000 Feldene Anti-inflammatory 100,000 Death PMA (paraMethoxyamphetamine) Amphetamine analog 100,000 AMP 2,500 K-Dur Potassium chloride Electrolyte replenisher 100,000 Pima syrup Iodine supplement 200,000 Potassium nitrite Potassium nitrite Vasodialator 1,000,000 Potassium phosphate Potassium phosphate, dibasic Buffering agent 1,000,000 Protopam reactivator 100,000 Centrax Benzodiazepine 100,000 BZO 1,400 also metabolizes to Nordiazepam & Oxazepam Centrax metabolite Prazepam metab.(3-HydroxyPrazepam) Benzodiazepine metabolite 100,000 BZO 250 Minipress Antihypertensive 100,000 Prednisolone Glucocorticoid 100,000 Decortin Prednisone Glucocorticoid 100,000 also metabolizes to Prednisolone PDG Pregnanediol glucuronide (PDG) Estrogen 100,000 Citanest Anesthetic 200,000 Primaquine Primaquine Antimalarial 100,000 Mysoline Anticonvulsant 100,000 also metabolizes to Phenobarbital

Sources: 1. Merck Index 2.Disposition of Toxic Drugs Chemicals in Man 3. Physicians Desk Reference 2000 Rev.A 10-8-2002 TOX Specificity-Chemical Name Biosite Inc. Page 22

Highest Conc. Tested Conc. Giving Positive TRADE NAME CHEMICAL NAME DRUG CLASS (ng/ml) (ng/ml) Mysoline metabolite Primidone metab.(Ethyl-2-phenylmalonamide, 2-) Primidone metabolite 100,000 Benemid Probenecid Antigout 100,000 Pronestyl Antiarrhythmic 100,000 Pronestyl metabolite Procainamide metab.(N-Acetylprocainamide) Procainamide metabolite 100,000 Novacain Anesthetic 100,000 Compazine Antiemetic 100,000 Kemadrin Anticholinergic 100,000 Prometrium Progestogen 100,000 Progesterone metab.(Pregnen-3ß-ol-20-one, delta 5-) Progesterone metabolite 100,000 Sparine Antipsychotic 100,000 Phenergan Antihistaminic 100,000 Alcaine Proparacaine Anesthetic 100,000 Dorevane Sedative 100,000 Tranvet Propionylpromazine Tranquilizer 100,000 Diprivan Anesthetic 100,000 Darvon Propoxyphene () Narcotic analgesic 100,000 Darvon metabolite Propoxyphene metab.() Propoxyphene metabolite 100,000 Inderal metabolite metab.(Naphthol, a-) Propranolol metabolite 100,000 Inderal metabolite Propranolol metab.(Naphthoxyacetic acid, 2-) Propranolol metabolite 100,000 Inderal Propranolol, d,l- Antihypertensive 100,000 Propylamphetamine Amphetamine analog 100,000 Propylbenzene Propylbenzene Solvent 1,000,000 Obesin Decongestant 100,000 Vivactil Tricyclic antidepressant 100,000 TCA 3,300 Sudafed metabolite metab.(Norpseudoephedrine, d-) Pseudoephedrine metabolite 1,000,000 Sudafed metabolite Pseudoephedrine metab.(Norpseudoephedrine, l-) Pseudoephedrine metabolite 100,000 Sudafed Pseudoephedrine, d- Decongestant 1,000,000 Sudafed Pseudoephedrine, l- Pseudoephedrine isomer 1,000,000 Psilocybin Hallucinogen 100,000 Psilocin Psilocybin metabolite 100,000 Putrescine Putrescine precursor 100,000 Mestinon Pyridostigmine Cholinergic 100,000 Vitamin B6 Pyridoxine Vitamin 200,000 Triaminic Pyrilamine Antihistamine 100,000 Dormalin/Prosedar metabolite metab.(2-Oxo-Quazepam) Benzodiazepine metabolite 100,000 BZO 100

Sources: 1. Merck Index 2.Disposition of Toxic Drugs Chemicals in Man 3. Physicians Desk Reference 2000 Rev.A 10-8-2002 TOX Specificity-Chemical Name Biosite Inc. Page 23

Highest Conc. Tested Conc. Giving Positive TRADE NAME CHEMICAL NAME DRUG CLASS (ng/ml) (ng/ml) Seroquel Quetiazepine Antipsychotic 100,000 Acriquine Quinacrine Antimalarial 100,000 Quiniglute Antiarrhythmic 100,000 Quinine Antimalarial 100,000 Zantac Anti-ulcerative 500,000 Rauwolfia Rauwolfia serpentina Antihypertensive 1,000,000 Edronax Reboxitine Antipsychotic 100,000 Moderil Rescinnamine Antihypertensive 500,000 Reserpex Antihypertensive 100,000 Accutane Retinoic acid Keratolytic 100,000 vitamin B2 Riboflavin Vitamin 75,000 Rifadin Rifampin Antibiotic 100,000 Rimcazole Antipsychotic 100,000 Actonel Risendronate Bone reabsorption inhibitor 200,000 Risperdal Antipsychotic 100,000 Risperdal metabolite Risperidone, 9-OH- Risperidone metabolite 100,000 Miolene Tocolytic 100,000 Vioxx Anti-imflammatory 100,000 Succaryl Saccharin Non-caloric sweetener 10,000,000 Anabar Analgesic 100,000 Hyoscine Anticholinergic 100,000 Seconal Barbiturate 100,000 BAR 300 Deprenyl Antiparkinsonian 100,000 also metabolizes to l-Methamphetamine Enteramine (5-hydroxytryptamine) Neurotransmitter 100,000 THC 20,000 Enteramine metabolite Serotonin metab.(Hydroxy (5) indole-3-acetic acid) Serotonin metabolite 100,000 Zoloft Antidepressant 100,000 Zoloft metabolite Sertraline metab.() Sertraline metabolite 100,000 Meridia Anorexic 100,000 Viagra Treat erectile dysfuntion 100,000 Zocor Simvastatin Antihyperlipidemic 100,000 THC 60,000 Baking soda Antacid 1,000,000 Sodium borate Sodium borate Antiseptic 100,000 Salt Sodium chloride Electrolyte replenisher 60,000,000 Luride Sodium fluoride Anthelmintic 100,000

Sources: 1. Merck Index 2.Disposition of Toxic Drugs Chemicals in Man 3. Physicians Desk Reference 2000 Rev.A 10-8-2002 TOX Specificity-Chemical Name Biosite Inc. Page 24

Highest Conc. Tested Conc. Giving Positive TRADE NAME CHEMICAL NAME DRUG CLASS (ng/ml) (ng/ml) Sodium formate Sodium formate Astringent 100,000 Sodium nitrite Food preservative 2,000,000 Sodium phosphate Sodium phosphate, dibasic Cathartic 1,000,000 Sorbol Sorbital Laxative 100,000 Betapace Antianginal 100,000 Aldactone Spironolactone Diuretic 100,000 Winstrol Stanozolol Androgen 100,000 Strychnine Strychnine Stimulant 100,000 Anectine Succinylcholine Muscle relaxant 100,000 Sulfadiazine Sulfadiazine Antibacterial 100,000 Sulfaguine Sulfaguanidine Antibacterial 100,000 Vesadin Sulfamethazine Antibacterial 100,000 Bactrim/Septra Sulfamethoxazole Antibacterial 1,000,000 AVC/Prontosil Sulfanilamide Antibacterial 100,000 Orisulf Sulfaphenazole Antibacterial 100,000 Cibazol Sulfathiazole Antibacterial 100,000 Sulfoxol Sulfisoxazole Antibacterial 100,000 Clinoril Anti-inflammatory 100,000 Dobren Antidepressant 100,000 Imitrex Antimigraine 100,000 Antrypol Suramin Anthelmintic 100,000 Danilon Anti-inflammatory 100,000 Lotusate Barbiturate 100,000 BAR 200 Nolvadex Tamoxifen Antiestrogen 100,000 Tannin Tannic acid Astringent 100,000 Taxol Taxol Antineoplastic 100,000 PCP analog TCM (1-[1-(2-Thienyl)cyclohexyl]-morpholine) PCP analog 100,000 PCP 10,000 PCP analog TCP (1-[1-(2-Thienyl)cyclohexyl]-) PCP analog 300,000 PCP analog TCPy (1-[1-(2-Thienyl)cyclohexyl]-pyrrolidine) PCP analog 100,000 PCP 250 Restoril Temazepam Benzodiazepine 100,000 BZO 200 also metabolizes to Oxazepam & Oxazepam glucuronide Restoril metabolite Temazepam glucuronide Benzodiazepine metabolite 10,000 BZO 1,000 Tilcotil Anti-inflammatory 100,000 Brethine Bronchodilator 100,000 Seldane Antihistamine 100,000

Sources: 1. Merck Index 2.Disposition of Toxic Drugs Chemicals in Man 3. Physicians Desk Reference 2000 Rev.A 10-8-2002 TOX Specificity-Chemical Name Biosite Inc. Page 25

Highest Conc. Tested Conc. Giving Positive TRADE NAME CHEMICAL NAME DRUG CLASS (ng/ml) (ng/ml) also metabolizes to Fexofenadine Dironyl Antiparkinsonian 100,000 Androderm Androgen 100,000 Cetacaine Anesthetic 100,000 Achromycin Tetracycline Antibacterial 100,000 Visine Tetrahydrozyline Adrenergic 100,000 THC THC() 100,000 THC THC(Cannabinol) Cannabinoid 100,000 THC 20,000 THC THC(Cannabinol, D8-) Cannabinoid 200,000 THC 5,000 THC/Marinol THC(Cannabinol, D9-) Cannabinoid 1,000,000 THC 40,000 THC THC, 11-nor-9-carboxy-D8- Cannabinoid 100,000 THC 4,000 THC THC, l-11-Hydroxy-D9- Cannabinoid 10,000 THC 10,000 THC THC, l-11-nor-9-carboxy-D9- Cannabinoid 10,000 THC 50 THC THC, l-11-nor-9-carboxy-D9-glucuronide Cannabinoid metabolite 1,000 THC 50 Paramorphine Opiate 100,000 OPI 24,000 Diuretin Theobromine Diuretic 100,000 Aminophylline Bronchodilator 100,000 Aminophylline metabolite Theophylline metab.(Dimethyluric acid, 1,3-) Theophylline metabolite 100,000 Vitamin B1 Thiamine Vitamin 100,000 Surital Anesthetic 100,000 BAR 40,000 Merthiolate Thimerosal Anti-infective 1,000,000 Pentothal Thiopental Anesthetic/Barbiturate 100,000 also metabolizes to Pentobarbital Mellaril Antipsychotic 100,000 also metabolizes to Mesoridazine Navane Thiothixene Antipsychotic 100,000 Anahist Antihistamine 200,000 camphor Antiseptic 100,000 Dynothel Thyroxine Thyroid hormone 100,000 Ticlid Ticlopidine Antiplatelet aggregation factor 1,000,000 Timolide Antihypertensive 100,000 Nebcin Tobramycin Antibacterial 100,000 Tonocard Antiarrhythmic 100,000 Tolinase Antidiabetic 100,000 Orinase Antidiabetic 100,000

Sources: 1. Merck Index 2.Disposition of Toxic Drugs Chemicals in Man 3. Physicians Desk Reference 2000 Rev.A 10-8-2002 TOX Specificity-Chemical Name Biosite Inc. Page 26

Highest Conc. Tested Conc. Giving Positive TRADE NAME CHEMICAL NAME DRUG CLASS (ng/ml) (ng/ml) Tolfedine Anti-inflammatory analgesic 1,000,000 Tolectin Anti-inflammatory 100,000 Toluene Organic solvent 100,000 Tracazolate Anxiolytic 100,000 Tramal/Ultram Analgesic 1,000,000 Tramal metabolite Tramadol M-1 metabolite Tramadol metabolite 1,000,000 Parnate Antidepressant 100,000 Desyrel metabolite Trazadone metab.(Piperazine, 1-(3-chlorophenyl)-) metabolite 100,000 Desyrel Trazodone Antidepressant 100,000 Aristospan/Azmacort Glucocorticoid 100,000 Dyazide Diuretic 100,000 Halcion Benzodiazepine 100,000 BZO 50 Halcion metabolite Triazolam, 4-OH- Benzodiazepine metabolite 100,000 BZO 100 Halcion metabolite Triazolam, a-OH- Benzodiazepine metabolite 100,000 BZO 100 Diurese Trichlormethiazide Diuretic 100,000 Stelazine Antipsychotic 100,000 Vetame Antipsychotic 100,000 Artane Anticholinergic 100,000 Vallergan Trimeprazine 100,000 Tridone Anticonvulsant 100,000 Tigan Antiemetic 1,000,000 TMP/Bactrim/Septra Trimethoprim Antibacterial 100,000 Surmontil Tricyclic antidepressant 100,000 TCA 3,000 Pyribenzamine Antihistamine 100,000 Actifed Antihistamine 100,000 Tropicamide Anticholinergic 100,000 Tryptamine Amino acid 100,000 Kalma Antidepressant 100,000 Kalma metabolite Tryptophan metab.() Tryptophan metabolite 100,000 Kalma metabolite Tryptophan metab.(Quinolinic acid) Tryptophan metabolite 100,000 Tubadil Tubocurarine Muscle relaxant 100,000 Uteramin Adrenergic 1,000,000 AMP 200,000 Tyrosine, d,l- Tyrosine, d,l- Amino acid 1,000,000 Pastaron Urea Diuretic 60,000,000 Uric acid Uric acid Urine component 100,000

Sources: 1. Merck Index 2.Disposition of Toxic Drugs Chemicals in Man 3. Physicians Desk Reference 2000 Rev.A 10-8-2002 TOX Specificity-Chemical Name Biosite Inc. Page 27

Highest Conc. Tested Conc. Giving Positive TRADE NAME CHEMICAL NAME DRUG CLASS (ng/ml) (ng/ml) Depakene Valproic acid Anticonvulsant 500,000 Vancocin Vancomycin Antibacterial 100,000 Effexor Antidepressant 100,000 Calan/Isoptin Antiarrhythmic 1,000,000 Calan/Isoptin metabolite Verapamil metab.() Verapamil metabolite 100,000 Novicet Vincamine Vasodilator 100,000 Coumadin Warfarin (3-(a-acetonylbenzyl)-4-hydroxycourmarin) Anticoagulant 100,000 Xymelin Adrenergic 100,000 Yohimex/Aphrodyne Mydriatic 200,000 Zearalenone Zearalenone Anabolic 100,000 THC 60,000 Retrovir Zidovudine/AZT Antiviral 1,000,000 Zelmid Zimeldine Antidepressant 100,000 Ambien Hypnotic 100,000 Zomax Analgesic 100,000 Imovane Sedative 100,000 Flexin Muscle relaxant 500,000

Sources: 1. Merck Index 2.Disposition of Toxic Drugs Chemicals in Man 3. Physicians Desk Reference 2000 Rev.A 10-8-2002 TOX Specificity-Trade Name Biosite Inc. Page 28

Highest Conc. Tested Conc. Giving Positive TRADE NAME CHEMICAL NAME DRUG CLASS (ng/ml) (ng/ml) Accutane Retinoic acid Keratolytic 100,000 Acetanilide Acetanilide Analgesic 100,000 Acetone Acetone Solvent 10,000,000 Achromycin Tetracycline Antibacterial 100,000 Acriquine Quinacrine Antimalarial 100,000 Actifed Triprolidine Antihistamine 100,000 Actonel Risendronate Bone reabsorption inhibitor 200,000 Acyclovir Acyloguanosine Antiviral 100,000 Adalat Nifedipine Antianginal 100,000 Adderall metabolite Amphetamine metab.(Hippuric acid) Amphetamine metabolite 100,000 Adderall metabolite Amphetamine metab.(Hydroxynorephedrine, p-) Amphetamine metabolite 100,000 Adderall/Dexedrine/Benzadrine Amphetamine, d- Amphetamine 100,000 AMP 1,000 Adipex-P Phentermine Anorexic 100,000 Adrenalin Epinephrine, l- Adrenergic 1,000,000 Adrenalin metabolite Epinephrine metab.(Metanephrine) Epinephrine metabolite 300,000 Adrenalin metabolite Epinephrine metab.(Normetanephrine) Epinephrine metabolite 100,000 Adrenalin metabolite Epinephrine metab.(Vanillylmandelic acid, d,l-) Epinephrine metabolite 200,000 Adrenor Norepinephrine, l- Adrenergic 1,000,000 Adrenor metabolite Norepinephrine metab(d,l-Hydroxy-3-methoxyphenyl glycol4-) Norepinephrine metabolite 200,000 Adrenor metabolite Norepinephrine metab.(d,l-Dihydroxymandelic acid,3,4-) Norepinephrine metabolite 200,000 Adrenor metabolite Norepineprine metab.(d,l-Dihydroxyphenylglycol,3,4-) Norepinephrine metabolite 200,000 Ajan Nefopam Antidepressant 100,000 Akarpine Pilocarpine Antiglaucoma 100,000 Akatinol Memantine Muscle relaxant 100,000 Akineton Biperiden Anticholinergic 100,000 Alcaine Proparacaine Anesthetic 100,000 Alcohol Ethanol Antiseptic 20,000,000 Aldactone Spironolactone Diuretic 100,000 Aldomet Methyldopa Antihypertensive 100,000 Aleve Naproxen Anti-inflammatory 100,000 Alkeran Melphalan Antineoplastic 100,000 Allegra Fexofenadine Antihistamine 100,000 Alphenal Phenallylmal Barbiturate 100,000 BAR 100 Alupent Metaproterenol Bronchodilator 200,000

Sources: 1. Merck Index 2. Disposition of Toxic Drugs and Chemicals in Man 3. Physicians Desk Reference 2000 Rev.A 10-8-2002 TOX Specificity-Trade Name Biosite Inc. Page 29

Highest Conc. Tested Conc. Giving Positive TRADE NAME CHEMICAL NAME DRUG CLASS (ng/ml) (ng/ml) Alurate Aprobarbital Barbiturate 100,000 BAR 200 Ambien Zolpidem Hypnotic 100,000 Ambisone Amphotericin Antifungal 100,000 Americaine Benzocaine Anesthetic 100,000 Amikin Amikacin Antibacterial 100,000 Aminophylline Theophylline Bronchodilator 100,000 Aminophylline metabolite Theophylline metab.(Dimethyluric acid, 1,3-) Theophylline metabolite 100,000 Amoxil Amoxicillin Antibacterial 100,000 Amphetamine analog Amphetamine analog(Ethylamphetamine, N-) Amphetamine analog 100,000 MeAMP 12,500 Ampicin Ampicillin Antibacterial 100,000 Ampyrone Aminopyrine, l- Antipyretic 100,000 Amytal Amobarbital Barbiturate 100,000 BAR 100 Anabar Salicylamide Analgesic 100,000 Anadrol Oxymetholone Androgen 100,000 Anafranil Clomipramine Tricyclic antidepressant 100,000 TCA 12,500 Anafranil metabolite Clomipramine metab.(Norclomipramine) Clomipramine metabolite 100,000 TCA 75,000 Anahist Thonzylamine Antihistamine 200,000 Analgesine Antipyrine Analgesic 1,000,000 Androderm Testosterone Androgen 100,000 Anectine Succinylcholine Muscle relaxant 100,000 Angibid Nitroglycerin Antianginal 100,000 Antabuse Disulfiram Alcohol deterrent 100,000 Antilirium Physostigmine Cholinergic 100,000 Antilirium metabolite Physostigmine metab. (Eseroline) Analgesic 100,000 Antiobes Fenproporex Anorexic 100,000 Antivert Meclizine Antiemetic 100,000 Antrypol Suramin Anthelmintic 100,000 Aparasin Lindane Pediculicide 100,000 APC tablets Phenacetin Analgesic 100,000 Aphamite Parathion Insecticide 1,000,000 Aphrodyne Yohimbine Mydriatic 200,000 Apocodeine Apocodeine Emetic 100,000 Apresoline Hydralazine Antihypertensive 100,000 Aralen Chloroquine Antimalarial 100,000

Sources: 1. Merck Index 2. Disposition of Toxic Drugs and Chemicals in Man 3. Physicians Desk Reference 2000 Rev.A 10-8-2002 TOX Specificity-Trade Name Biosite Inc. Page 30

Highest Conc. Tested Conc. Giving Positive TRADE NAME CHEMICAL NAME DRUG CLASS (ng/ml) (ng/ml) Aramine Metaraminol Adrenergic 500,000 Aricept Donepezil Acetylcholinesterase inhibitor 200,000 Aristospan/Azmacort Triamcinolone Glucocorticoid 100,000 Arlidin Nylidrin Vasodilator 100,000 Arresten Meticrane Diuretic 100,000 Arsemetine Emetine Antiamebic 100,000 Artane Trihexyphenidyl Anticholinergic 100,000 Ascendin Amoxapine Antidepressant 100,000 Aspirin Acetylsalicylic acid Analgesic 1,000,000 Aspirin metabolite Acetylsalicylic acid metab.(Salicylic acid) Aspirin metabolite 1,000,000 Aspirin metabolite Acetylsalicylic acid metab.(Salicyluric acid) Aspirin metabolite 100,000 Assugrin Cyclamic acid Non-nutritive sweetener 10,000,000 Astrobain Ouabain Cardiotonic 100,000 Atarax Hydroxyzine Antihistamine/ Sedative 100,000 Ativan Lorazepam Benzodiazepine 100,000 BZO 200 Ativan metabolite Lorazepam glucuronide Benzodiazepine metabolite 10,000 BZO 300 Atromid Clofibrate Antihyperlipoproteinic 500,000 Atrovent Ipratropium Bronchodilator 100,000 AVC Sulfanilamide Antibacterial 100,000 Aventyl Nortriptyline Tricyclic antidepressant 100,000 TCA 1,100 Aventyl metabolite Nortriptyline metabolite (+/- E-10-hydroxylated) Nortriptyline metabolite 100,000 TCA 750 Aventyl metabolite Nortriptyline metabolite (+/- Z-10-hydroxylated) Nortriptyline metabolite 100,000 TCA 5,000 Avlosulfon Dapsone Antibacterial 100,000 THC 40,000 Axid Nizatidine Antiulcerative 100,000 Baclon Baclofen Muscle relaxant 10,000 Bactrim Sulfamethoxazole Antibacterial 1,000,000 Bactrim Trimethoprim Antibacterial 100,000 Baking soda Sodium bicarbonate Antacid 1,000,000 BAL Dimercaprol Chelating agent 100,000 Barbitone Barbital Barbiturate 100,000 BAR 150 Baycol Cerivastatin Antihyperlipidemic 10,000 BDB BDB(d,l-1-(3,4-Methylenedioxyphenyl)-2-Butanamine) MBDB metabolite 100,000 AMP 2,500 Benadryl Diphenhydramine Antihistamine/ Sedative 1,000,000 Benemid Probenecid Antigout 100,000

Sources: 1. Merck Index 2. Disposition of Toxic Drugs and Chemicals in Man 3. Physicians Desk Reference 2000 Rev.A 10-8-2002 TOX Specificity-Trade Name Biosite Inc. Page 31

Highest Conc. Tested Conc. Giving Positive TRADE NAME CHEMICAL NAME DRUG CLASS (ng/ml) (ng/ml) Bentyl Dicyclomine Anticholinergic 100,000 Benzidine Benzidine Dye 100,000 Bepadin/Vascor Bepridil Antianginal 100,000 Berberine Berberine Antibacterial 100,000 Betapace Sotalol Antianginal 100,000 Bevitamel Melatonin Pineal hormone 100,000 Bicillin Penicillin G Antibacterial 100,000 Bicillin Penicillin V Antibacterial 100,000 Bilirubin Bilirubin Bile pigment 2,500 Birth Control Pills Ethinyl estradiol Estrogen/Contraceptive 100,000 Birth Control Pills Norethindrone Progestogen/Contraceptive 100,000 Boldenone Dehydrotestosterone, 1- Androgen 100,000 Bontril Phendimetrazine Anorexic 100,000 Brethine Terbutaline Bronchodilator 100,000 Brevital Methohexital Anesthetic/Barbiturate 1,000,000 Bumex Bumetanide Diuretic 100,000 Bunt-cure Hexachlorobenzene Fungicide 100,000 Buprenex Buprenorphine Narcotic analgesic 1,000,000 BuSpar Buspirone Anxiolytic 1,000,000 Butanal Butyraldehyde Solvent 100,000 Butazolidin Phenylbutazone Anti-inflammatory 100,000 Butelline Butacaine Anesthetic 100,000 Butisol Butabarbital Barbiturate 100,000 BAR 200 Caffeine Caffeine Stimulant 2,000,000 Caffeine metabolite Caffeine metab.(Dimethyluric acid, 1,7-) Caffeine metabolite 100,000 Caffeine metabolite Caffeine metab.(Dimethyluric acid, 1,9-) Caffeine metabolite 100,000 Caffeine metabolite Caffeine metab.(Dimethyluric acid, 3,7-) Caffeine metabolite 100,000 Caffeine metabolite Caffeine metab.(Dimethyluric acid, 3,9-) Caffeine metabolite 100,000 Caffeine metabolite Caffeine metab.(Dimethyluric acid, 7,9-) Caffeine metabolite 100,000 Caffeine metabolite Caffeine metab.(Paraxanthine) Caffeine metabolite 100,000 Calan Verapamil Antiarrhythmic 1,000,000 Calan metabolite Verapamil metab.(Norverapamil) Verapamil metabolite 100,000 Camphor Camphor Topical Antiseptic 100,000 Cantor Minaprine Psychotropic 100,000

Sources: 1. Merck Index 2. Disposition of Toxic Drugs and Chemicals in Man 3. Physicians Desk Reference 2000 Rev.A 10-8-2002 TOX Specificity-Trade Name Biosite Inc. Page 32

Highest Conc. Tested Conc. Giving Positive TRADE NAME CHEMICAL NAME DRUG CLASS (ng/ml) (ng/ml) Capoten Captopril Antihypertensive 100,000 Carbital Carbromal Sedative 5,000,000 Carbolic acid Phenol Topical Antiseptic 100,000 Carbylderm Carbaryl Pediculocide 100,000 Carcholin Carbachol Cholinergic 100,000 Cardizem Diltiazem Antianginal/Antiarrhythmic 1,000,000 Cardizole Pentylenetetrazole Central stimulant 100,000 Catapres Clonidine Antihypertensive 100,000 Ceclor Cefaclor Antibacterial 100,000 Cedad Benactyzine Antidepressant 100,000 Ceftin Cefuroxime Antibacterial 100,000 Celebrex Celecoxib Anti-imflammatory 200,000 Celestone Betamethasone Glucocorticoid 100,000 Celexa Citalopram Antidepressant 100,000 Celontin Methsuximide Anticonvulsant 100,000 Celontin metabolite Methsuximide metab.(Normethsuximide) Methsuximide metabolite 100,000 Centrax Prazepam Benzodiazepine 100,000 BZO 1,400 Centrax metabolite Prazepam metab.(3-HydroxyPrazepam) Benzodiazepine metabolite 100,000 BZO 250 Ceporan Cephaloridine Antibacterial 100,000 Cesporan Cephradine Antibacterial 200,000 Cetacaine Tetracaine Anesthetic 100,000 Chloroamphetamine, 4- Chloroamphetamine, 4- Amphetamine 200,000 AMP 2,300 Chlorodiazepam, 4- Chlorodiazepam, 4- Benzodiazepine 100,000 THC 20,000 Chloromycetin Chloramphenicol Antibacterial 100,000 Chlor-Trimeton Chlorpheniramine Antihistamine 100,000 Chocolax Phenolphthalein Laxative 100,000 Cholesterol Cholesterol Emulsifying agent 100,000 Cibazol Sulfathiazole Antibacterial 100,000 Cinchovatine Cinchonidine Antimalarial 100,000 Cinobal Cinoxacin Antibacterial 100,000 Cipro Ciprofloxacin Antibacterial 100,000 Citanest Prilocaine Anesthetic 200,000 Claforan Cefotaxime Antibacterial 100,000 Claritin Loratadine Antihistamine 200,000

Sources: 1. Merck Index 2. Disposition of Toxic Drugs and Chemicals in Man 3. Physicians Desk Reference 2000 Rev.A 10-8-2002 TOX Specificity-Trade Name Biosite Inc. Page 33

Highest Conc. Tested Conc. Giving Positive TRADE NAME CHEMICAL NAME DRUG CLASS (ng/ml) (ng/ml) Clemanil Clemastine Antihistamine 100,000 Cleocin Clindamycin Antibacterial 100,000 Clinoril Sulindac Anti-inflammatory 100,000 Clofilium Clofilium Anti-arrhythmic 100,000 Cloxapen Cloxacillin Antibacterial 100,000 Clozaril Clozapine Antipsychotic 100,000 Clozaril metabolite Clozapine metab.(Desmethylclozapine) Clozapine metabolite 100,000 THC 40,000 Cocaine Cocaine Anesthetic 100,000 COC 100,000 Cocaine analog Cocaine analog(Propylbenzoylecgonine) Benzoylecgonine analog 100,000 Cocaine analog Cocaine analog(Tropacocaine) Cocaine analog 200,000 Cocaine byproduct Cocaine byproduct(Ecgonidine methyl ester) Anesthetic 100,000 Cocaine byproduct Cocaine byproduct(Ecgonine) Anesthetic 100,000 COC 133,000 Cocaine homolog Cocaine analog(Cocaethylene) Cocaine homolog 100,000 Cocaine metabolite Cocaine metab.(Benzoylecgonine) Cocaine metabolite 100,000 COC 300 Cocaine metabolite Cocaine metab.(Benzoylnorecgonine) Benzoylecgonine metab. 100,000 COC 100,000 Cocaine metabolite Cocaine metab.(Ecgonine methyl ester) Cocaine metabolite 100,000 Cocaine metabolite Cocaine metab.(Norcocaine) Cocaine metabolite 100,000 Cocculin Picrotoxin CNS stimulant 100,000 Codeine Codeine Narcotic analgesic 100,000 OPI 300 Codeine metabolite Codeine metab.(Norcodeine) Codeine metabolite 300,000 OPI 300,000 Cogentin Benztropine mesylate Anticholinergic 100,000 Colbenemid Colchicine Antineoplastic 100,000 Combipress Chlorthalidone Diuretic 100,000 Compazine Prochlorperazine Antiemetic 100,000 Contralac Metergoline Prolactin inhibitor 100,000 Cordarone Amiodarone Antiarrhythmic 100,000 Cordran Flurandrenolide Glucocorticoid 100,000 Cortazac Hydrocortisone Glucocorticoid 100,000 Cortazac metabolite Hydrocortisone metab.(Cortol, ß-) Hydrocortisone metabolite 100,000 Cortelan Cortisone Glucocorticoid 100,000 Cortelan metabolite Cortisone metab.(Cortolone, ß-) Cortisone metabolite 100,000 Cortelan metabolite Cortisone metab.(Tetrahydrocortisone) Cortisone metabolite 100,000 Cortexone Deoxycorticosterone Mineralocorticoid 100,000 Corticosterone Corticosterone Glucocorticoid 100,000

Sources: 1. Merck Index 2. Disposition of Toxic Drugs and Chemicals in Man 3. Physicians Desk Reference 2000 Rev.A 10-8-2002 TOX Specificity-Trade Name Biosite Inc. Page 34

Highest Conc. Tested Conc. Giving Positive TRADE NAME CHEMICAL NAME DRUG CLASS (ng/ml) (ng/ml) Corzide Nadolol Antihypertensive 200,000 Corzide Bendroflumethiazide Diuretic 100,000 Coumadin Warfarin (3-(a-acetonylbenzyl)-4-hydroxycourmarin) Anticoagulant 100,000 Creatinine Creatinine Creatine metabolite 5,000,000 Cuprimine Penicillamine Chelating agent 100,000 Cyclazocine Cyclazocine Narcotic antagonist 100,000 Cyclopal Cyclopentobarbital Barbiturate 100,000 BAR 100 Cydril Amphetamine, l- Amphetamine 100,000 AMP 63,500 Cyheptamide Cyheptamide Anticonvulsant 100,000 Cylert Pemoline CNS stimulant 100,000 Cylocort Amcinonide Glucocorticoid 100,000 Cytoxin Cyclophosphamide Antineoplastic 2,000,000 Cytradren Aminoglutethimide Anticonvulsant 100,000 Dalmane Flurazepam Benzodiazepine 100,000 BZO 100 Dalmane metabolite Flurazepam metab.(Desalkylflurazepam) Benzodiazepine 100,000 BZO 200 Dalmane metabolite Flurazepam metab.(N-Hydroxyethyl Flurazepam) Flurazepam metabolite 100,000 BZO 50 Danilon Suxibuzone Anti-inflammatory 100,000 Danocrine Danazol Antigonadotropin 100,000 Dantrium Dantrolene Muscle relaxant 100,000 Daranide Dichlorphenamide Carbonic AnhydraseInhibitor 100,000 Darvon Propoxyphene (Dextropropoxyphene) Narcotic analgesic 100,000 Darvon metabolite Propoxyphene metab.(Norpropoxyphene) Propoxyphene metabolite 100,000 Daypro Oxaprozin Anti-inflammatory 100,000 Death PMA (paraMethoxyamphetamine) Amphetamine analog 100,000 AMP 2,500 Decadron Dexamethasone Anti-inflammatory 100,000 Declinax Debrisoquin Antihypertensive 100,000 Declomycin Demeclocycline Antibacterial 100,000 Decortin Prednisone Glucocorticoid 100,000 Delorazepam Delorazepam Benzodiazepine 100,000 BZO 600 Demerol Meperidine Narcotic analgesic 100,000 Demerol metabolite Meperidine metab.(Normeperidine) Meperidine metabolite 100,000 Demoxepam Demoxepam Benzodiazepine 100,000 BZO 7,700 Depakene Valproic acid Anticonvulsant 500,000 Depo-Provera Medroxyprogesterone Contraceptive 100,000

Sources: 1. Merck Index 2. Disposition of Toxic Drugs and Chemicals in Man 3. Physicians Desk Reference 2000 Rev.A 10-8-2002 TOX Specificity-Trade Name Biosite Inc. Page 35

Highest Conc. Tested Conc. Giving Positive TRADE NAME CHEMICAL NAME DRUG CLASS (ng/ml) (ng/ml) Deprenyl Selegiline Antiparkinsonian 100,000 Deracyn Adinazolam Benzodiazepine 100,000 BZO 1,000 Deracyn metabolite Adinazolam, Desmethyl Benzodiazepine metabolite 100,000 BZO 250 Desferal Deferoxamine Chelating agent 100,000 Desoxyn metabolite Methamphetamine metab.(Hydroxy methamphetamine, p-) Methamphetamine metabolite 100,000 MeAMP 2,500 Desoxyn/Speed/Ice/Crystal Methamphetamine, d- Amphetamine 100,000 MeAMP 1,000 Desyrel Trazodone Antidepressant 100,000 Desyrel metabolite Trazadone metab.(Piperazine, 1-(3-chlorophenyl)-) Trazodone metabolite 100,000 Dexatrim Phenylpropanolamine(Norephedrine, l-) Decongestant 1,000,000 Dextrose Glucose Sugar 20,000,000 Diabenese Chlorpropamide Antidiabetic 1,000,000 DiaBeta Glyburide (Glybenclamide) Antidiabetic 100,000 Diadol Allobarbital Barbiturate 100,000 BAR 150 Diamox Acetazolamide Diuretic 100,000 Dianabol Methandrostenolone Androgen 100,000 Dibenzyline Phenoxybenzamine Antihypertensive 100,000 THC 25,000 Dibotin Phenformin Antidiabetic 100,000 Dibutil Ethopropazine Antiparkinsonian 100,000 Didrex Benzphetamine Anorexic 100,000 Diflucan Fluconazole Antifungal 100,000 Digitalis Digitoxin Cardiotonic 100,000 Dilantin Phenytoin (Diphenylhydantoin, 5,5- ) Anticonvulsant 100,000 Dilantin metabolite Phenytoin metab(p-Hydroxyphenyl)-5-phenylhydantoin,d,l 5-) Anticonvulsant metabolite 100,000 Dilantin metabolite Phenytoin metab.(m-Hydroxyphenyl)-5-phenylhydantoin, 5-) Anticonvulsant metabolite 100,000 Dilaudid Hydromorphone Narcotic analgesic 100,000 OPI 1,700 Dilavase Isoxsuprine Vasodilator 100,000 Dimetane Brompheniramine Antihistaminic 100,000 Dionin Ethylmorphine Antitussive/Opiate 100,000 OPI 300 Diprivan Propofol Anesthetic 100,000 Dironyl Terguride Antiparkinsonian 100,000 Ditropan Oxybutynin Anticholinergic 100,000 Diucardin Hydroflumethiazide Diuretic 100,000 Diurese Trichlormethiazide Diuretic 100,000 Diuretin Theobromine Diuretic 100,000

Sources: 1. Merck Index 2. Disposition of Toxic Drugs and Chemicals in Man 3. Physicians Desk Reference 2000 Rev.A 10-8-2002 TOX Specificity-Trade Name Biosite Inc. Page 36

Highest Conc. Tested Conc. Giving Positive TRADE NAME CHEMICAL NAME DRUG CLASS (ng/ml) (ng/ml) Diuril Chlorothiazide Diuretic 100,000 DMSO Dimethyl sulfoxide Anti-inflammatory 10,000,000 DMT Dimethyltryptamine Hallucinogen 100,000 DMT metabolite Dimethyltryptamine metab.(Indole-3-acetic acid) Dimethyltryptamine metab. 100,000 DOB Dimethoxy-4-bromoamphetamine, 2,5- 5-HT-agonist 100,000 Dobren Sulpiride Antidepressant 100,000 Doburil Cyclothiazide Diuretic 100,000 Dobutrex Dobutamine Cardiotonic 100,000 Dolobid Diflunisal Analgesic 100,000 Dolophine Methadone, dl- Narcotic analgesic 100,000 Dolophine isomer Methadone, d- Methadone isomer 100,000 Dolophine metabolite Methadone primary metabolite(EDDP) Methadone metabolite 100,000 Dolophine metabolite Methadone secondary metabolite(EMDP) Methadone metabolite 100,000 DOM Dimethoxy-4-methylamphetamine, 2,5- 5-HT-agonist 100,000 Donnatal Atropine Anticholinergic 100,000 Donnatal Hyoscyamine, l- Anticholinergic 100,000 Donnatal metabolite Atropine metab.(Tropic acid) Atropine metabolite 100,000 Donnatal metabolite Atropine metab.(Tropine) Atropine metabolite 2,000,000 OPI 2,000,000 Dopamet Methyldopa Antihypertensive 100,000 Dopergin Lisuride Antimigraine 100,000 Dopram Doxapram Respiratory stimulant 100,000 Dorcalm Chloralose, a- Sedative 100,000 Dorevane Propiomazine Sedative 100,000 Doriden Glutethimide, d,l- Sedative 100,000 BAR 50,000 Dormalin/Prosedar metabolite Quazepam metab.(2-Oxo-Quazepam) Benzodiazepine metabolite 100,000 BZO 100 Dowacide Q Adamantane, (1-(3-Chloroallyl)-3,5,7-triaza-1-azonia)- Antibacterial 100,000 Drammamine Dimenhydrinate Antiemetic 100,000 Dridol Droperidol Antipsychotic 100,000 Dulcolax Bisacodyl Cathartic 100,000 Durazanil Bromazepam Benzodiazepine 100,000 BZO 750 Durazanil metabolite Bromazepam,Hydroxylated cleavage product Benzodiazepine metabolite 100,000 BZO 50,000 Duricef Cefadroxil Antibacterial 100,000 Dursban Chlorpyrifos Insecticide 100,000 Dyazide Triamterene Diuretic 100,000

Sources: 1. Merck Index 2. Disposition of Toxic Drugs and Chemicals in Man 3. Physicians Desk Reference 2000 Rev.A 10-8-2002 TOX Specificity-Trade Name Biosite Inc. Page 37

Highest Conc. Tested Conc. Giving Positive TRADE NAME CHEMICAL NAME DRUG CLASS (ng/ml) (ng/ml) Dymelor Acetohexamide Antidiabetic 1,000,000 Dynothel Thyroxine Thyroid hormone 100,000 E-3-G Estrone-3-glucuronide (E-3-G) Estrogen 100,000 Ecstasy MDMA (3,4-Methylenedioxymethamphetamine) Amphetamine analog 100,000 MeAMP 1,500 Edecrin Ethacrynic acid Diuretic 100,000 Edronax Reboxitine Antipsychotic 100,000 EDTA Ethylenediaminetetraacetic acid Chelating agent 100,000 Effexor Venlafaxine Antidepressant 100,000 Elavil Amitriptyline Tricyclic antidepressant 100,000 TCA 750 Elavil metabolite Amitriptyline metabolite(d,l-E-10-Hydroxy-Amitriptyline) Amitriptyline metabolite 100,000 TCA 250 Emivan Ethamivan Central stimulant 100,000 Emovate Clobetasone Anti-inflammatory 100,000 Enlon Edrophonium Cholinergic 100,000 Enteramine Serotonin (5-hydroxytryptamine) Neurotransmitter 100,000 THC 20,000 Enteramine metabolite Serotonin metab.(Hydroxy (5) indole-3-acetic acid) Serotonin metabolite 100,000 Ephedrine Ephedrine, d- Adrenergic 10,000,000 Ephedrine Ephedrine, l- Bronchodilator 10,000,000 MeAMP 400,000 Ephedrine metabolite Ephedrine, d- metab.(Norephedrine, d-) Ephedrine, d- metabolite 100,000 Epinine Deoxyepinephrine Vasoconstrictor 100,000 Epsom salts Magnesium sulfate Anticonvulsant 1,000,000 Equanil Meprobamate Sedative 100,000 Ergamisol Levamisole Antiparasitic 1,000,000 Ergocalm Lormetazepam Benzodiazepine 100,000 BZO 250 Ergomar Ergotamine Antimigraine 1,000,000 Erythrocin Erythromycin, l- Antibacterial 100,000 Eskalith Antimanic 200,000 Estrace Estradiol,17 ß- Estrogen 100,000 Estratest Methyltestosterone, 17-a- Androgen 100,000 Estrol Estrone Estrogen 100,000 Ethanal Acetaldehyde Solvent 10,000,000 Ethrane Enflurane Anesthetic 1,000,000 Ethylene glycol Ethylene glycol Solvent 10,000,000 Eunerpan Melperone Antipsychotic 100,000 Euphozid Iproniazid Antidepressant 100,000

Sources: 1. Merck Index 2. Disposition of Toxic Drugs and Chemicals in Man 3. Physicians Desk Reference 2000 Rev.A 10-8-2002 TOX Specificity-Trade Name Biosite Inc. Page 38

Highest Conc. Tested Conc. Giving Positive TRADE NAME CHEMICAL NAME DRUG CLASS (ng/ml) (ng/ml) Euporphin Apomorphine Emetic 100,000 Eutonyl Pargyline Antihypertensive 100,000 Euvitol Fencamfamine Central stimulant 1,000,000 Eve MDEA (3,4-Methylenedioxethylamphetamine) Amphetamine analog 100,000 MeAMP 4,600 Fastin Phentermine Anorexic 100,000 Feldene Piroxicam Anti-inflammatory 100,000 Feosol Ferrous sulfate Hematinic 10,000,000 Fiorinal Butalbital Barbiturate 100,000 BAR 150 Flagyl Metronidazole Antiprotazoal 1,000,000 Flexeril Cyclobenzaprine Muscle relaxant 100,000 TCA 1,900 Flexin Zoxazolamine Muscle relaxant 500,000 Floxin Ofloxacin Antibiotic 2,500,000 Fluanxol Flupenthixol Antipsychotic 100,000 Foliamin Folic acid Hematopoietic vitamin 1,000,000 Formalin Formaldehyde Antiseptic 10,000,000 Fosamax Alendronate Bone reabsorption inhibitor 200,000 Frisium Clobazam Benzodiazepine 100,000 BZO 2,000 Froben Flurbiprofen Anti-inflammatory 1,000,000 Furadantin Nitrofurantoin Antibacterial 100,000 Garamycin Gentamicin Antibacterial 100,000 Gemonil Metharbital Anticonvulsant/Barbiturate 1,000,000 BAR 1,400 Gentisod Gentisic acid Analgesic 100,000 GHB Gamma-Hydroxybutyric acid GABA metabolite 1,000,000 Glucophage Metformin(Dimethylbiguanide, 1,1-) Antidiabetic 100,000 Glucotrol Glipizide Antidiabetic 100,000 Gramoxone Paraquat Herbicide 100,000 Grifulvin Griseofulvin Antifungal 100,000 Grisactin Glycopyrrolate Anticholinergic 100,000 Gumbaral Adenosylmethionine, S- Anti-inflammatory 100,000 Halcion Triazolam Benzodiazepine 100,000 BZO 50 Halcion metabolite Triazolam, 4-OH- Benzodiazepine metabolite 100,000 BZO 100 Halcion metabolite Triazolam, a-OH- Benzodiazepine metabolite 100,000 BZO 100 Haldol Haloperidol Antidyskinetic 100,000 Haldol metabolite Haloperidol metabolite I Haloperidol metabolite 100,000

Sources: 1. Merck Index 2. Disposition of Toxic Drugs and Chemicals in Man 3. Physicians Desk Reference 2000 Rev.A 10-8-2002 TOX Specificity-Trade Name Biosite Inc. Page 39

Highest Conc. Tested Conc. Giving Positive TRADE NAME CHEMICAL NAME DRUG CLASS (ng/ml) (ng/ml) Haldol metabolite Haloperidol metabolite II Haloperidol metabolite 100,000 Haldol metabolite Haloperidol metabolite III Haloperidol metabolite 100,000 Halog Halcinonide Anti-inflammatory 100,000 Halothane Fluothane Anesthetic 500,000 HCTZ/Hyzaar Hydrochlorothiazide Diuretic 100,000 Heme Hemoglogin (Lysed Red Blood Cells) Protein 1,200,000 HEOD Dieldrin Insecticide 100,000 Heparin Heparin Anticoagulant 100,000 Heptin Aminoheptane, 2- Adrenergic 100,000 Heroin Diacetylmorphine Narcotic 100,000 OPI 300 Heroin byproduct Diacetylmorphine byproduct(Acetylcodeine, 6-) Opiate 100,000 OPI 250 Heroin metabolite Diacetylmorphine metab.(Acetylmorphine, 6- /6-MAM ) Narcotic Opiate 100,000 OPI 300 Hexadrin Endrin Insecticide 100,000 Hexanal Hexobarbital Barbiturate 100,000 Histadyl Methapyrilene Antihistamine/Sedative 1,000,000 Histazol Astemizole Antihistamine 100,000 THC 20,000 Homapin Homatropine Anticholinergic 100,000 HSA Albumin, Human Protein 5,000,000 Humulin Insulin Antidiabetic 100,000 Hydrastine/Goldenseal Hydrastine Diuretic 100,000 Hyoscine Scopolamine Anticholinergic 100,000 Hyperstat Diazoxide Antihypertensive 100,000 Imitrex Sumatriptan Antimigraine 100,000 Imodium Loperamide Antidiarrheal 100,000 Imovane Zopiclone Sedative 100,000 Imuran Azathioprine Antirheumatic 100,000 Imuthiol Diethyldithiocarbamic acid Chelating agent 100,000 Inderal Propranolol, d,l- Antihypertensive 100,000 Inderal metabolite Propranolol metab.(Naphthol, a-) Propranolol metabolite 100,000 Inderal metabolite Propranolol metab.(Naphthoxyacetic acid, 2-) Propranolol metabolite 100,000 Indocin Indomethacin Analgesic 100,000 Indole-3-butyric acid Indole-3-butyric acid Plant growth factor 100,000 Inovan Dopamine Cardiotonic 100,000 Inovan metabolite Dopamine metab.(Dihydroxyphenylacetic acid, 3,4-) Dopamine metabolite 100,000

Sources: 1. Merck Index 2. Disposition of Toxic Drugs and Chemicals in Man 3. Physicians Desk Reference 2000 Rev.A 10-8-2002 TOX Specificity-Trade Name Biosite Inc. Page 40

Highest Conc. Tested Conc. Giving Positive TRADE NAME CHEMICAL NAME DRUG CLASS (ng/ml) (ng/ml) Inovan metabolite Dopamine metab.(Methoxy-3-hydroxyphenethylamine, 4-) Dopamine metabolite 100,000 Intal Cromolyn Antiasthmatic 100,000 Ionamin Phentermine Anorexic 100,000 Ismelin Guanethidine Antihypertensive 200,000 Isopropanol Isopropanol Antiseptic 5,000,000 Isoptin Verapamil Antiarrhythmic 1,000,000 Isoptin metabolite Verapamil metab.(Norverapamil) Verapamil metabolite 100,000 Isordil Isosorbide Diuretic 100,000 Isotestosterone Epitestosterone Androgen 100,000 Kalma Tryptophan Antidepressant 100,000 Kalma metabolite Tryptophan metab.(Kynurenic acid) Tryptophan metabolite 100,000 Kalma metabolite Tryptophan metab.(Quinolinic acid) Tryptophan metabolite 100,000 Kantrex Kanamycin Antibacterial 100,000 K-Dur Potassium chloride Electrolyte replenisher 100,000 Keflex Cephalexin Antibacterial 100,000 Kemadrin Procyclidine Anticholinergic 100,000 Kepone Chlordecon Insecticide 100,000 Ketalar Ketamine Anesthetic 100,000 Khat/Qat (Catha edulis ) Cathinone Stimulant 100,000 Klonopin Clonazepam Benzodiazepine 100,000 BZO 250 Klonopin metabolite Clonazepam metab.(7-AminoClonazepam) Benzodiazepine metabolite 100,000 BZO 15,000 Kyanol Aniline Dye 200,000 LAAM Acetylmethadol, l-a- Narcotic analgesic 100,000 Laetrile Amygdalin Antineoplastic 1,000,000 Lanoxin Digoxin Cardiotonic 100,000 Laracor Oxprenolol Antihypertensive 100,000 Lasix Furosemide Diuretic 100,000 Lethidrone Nalorphine Narcotic antagonist 300,000 OPI 1,900 Leukerin Mercaptopurine, 6- Antineoplastic 100,000 Levaquin Levofloxacin Antibiotic 2,500,000 OPI 2,500,000 Levasole Levamisole Antiparasitic 1,000,000 Levodone Methadone, l- Narcotic analgesic 100,000 Levodopa Dopa, l- Antiparkinsonian 100,000 Levodopa metabolite Dopa, l- metab. (Homovanillic acid) l-Dopa metabolite 200,000

Sources: 1. Merck Index 2. Disposition of Toxic Drugs and Chemicals in Man 3. Physicians Desk Reference 2000 Rev.A 10-8-2002 TOX Specificity-Trade Name Biosite Inc. Page 41

Highest Conc. Tested Conc. Giving Positive TRADE NAME CHEMICAL NAME DRUG CLASS (ng/ml) (ng/ml) Levodopa metabolite Dopa, l metab.(Methoxy-4-hydroxyphenethylamine, 3-) l-Dopa metabolite 100,000 Levodopa metabolite Dopa, l metab.(3-o-Methyldopamine) l-Dopa metabolite 100,000 Levodopa metabolite Dopa, l-3-o-Methyl/Tyrosine, 3-Methoxy-l- l-Dopa metabolite 100,000 Levo-Dromoran Levorphanol (Dextrorphan, l-) Narcotic analgesic 100,000 OPI 25,000 Levonordefrin Methylnorepinephrine, (-) a- Vasoconstrictor 100,000 Levoprome Methotrimeprazine Analgesic 100,000 Librium Chlordiazepoxide Benzodiazepine 100,000 BZO 13,000 Librium metabolite Chlordiazepoxide-desmethyl Chlordiazepoxide metabolite 100,000 BZO 9,000 Lipitor Atorvastatin Antihyperlipidemic 100,000 Lodine Etodolac Anti-inflammatory 100,000 THC 50,000 Lomir Isradipine Antianginal 100,000 THC 90,000 Lomotil Diphenoxylate Antidiarrheal 100,000 Lopid Gemfibrozil Antihyperlipoproteinemic 100,000 Lopressor Metoprolol, d,l- Antihypertensive 100,000 Lorfan Levallorphan Narcotic antagonist 100,000 Lorivox Lorcainide Antiarrythmic 100,000 Lotusate Talbutal Barbiturate 100,000 BAR 200 Loxitane Loxapine Anxiolytic 100,000 Lozol Indapamide Diuretic 100,000 LSD Lysergic acid diethylamide Psychomimetic 2,500 LSD precursor-Lysergic acid Lysergic acid, d- LSD precursor 100,000 Ludiomil Maprotiline Antidepressant 100,000 Lufylin Dyphylline Bronchodilator 100,000 Luminal Phenobarbital Barbiturate 100,000 BAR 150 Luminal metabolite Phenobarbital metab.(Hydroxyphenobarbital, p-) Barbiturate 100,000 BAR 350 Luride Sodium fluoride Anthelmintic 100,000 Luvox Fluvoxamine Antidepressant 100,000 Lysine metabolite Pipecolic acid, l- Lysine metabolite 100,000 Malonylurea Barbituric acid Manuf. plastics 100,000 Mappine Bufotenine Hallucinogen 100,000 Marcaine Bupivacaine Anesthetic 1,000,000 Marezine Cyclizine Antiemetic 200,000 Maxiflor/Psorcon Diflorasone Anti-inflammatory 100,000 MBDB MBDB(d,l-Methyl-1(3,4-Methylenedioxyphenyl)2-Butanamine) MDMA analog 100,000 MeAMP 800

Sources: 1. Merck Index 2. Disposition of Toxic Drugs and Chemicals in Man 3. Physicians Desk Reference 2000 Rev.A 10-8-2002 TOX Specificity-Trade Name Biosite Inc. Page 42

Highest Conc. Tested Conc. Giving Positive TRADE NAME CHEMICAL NAME DRUG CLASS (ng/ml) (ng/ml) MDA MDA (3,4-Methylenedioxyamphetamine) Amphetamine analog 100,000 AMP 3,700 MDA, N-Hydroxy- MDA, N-Hydroxy- MDA analog 100,000 MDPA MDPA / Methylenedioxypropylamphetamine, 3,4- Amphetamine analog 100,000 Mebaral Mephobarbital Barbiturate 100,000 BAR 20,000 Meclomen Meclofenamic acid Anti-inflammatory 100,000 Medrol Methylprednisolone, 6-a- Glucocorticoid 100,000 Mefoxin Cefoxitin Antibacterial 100,000 MEGX Lidocaine metab.( Monoethylglycinexylidide) Lidocaine metabolite 100,000 Melanin Melanin Skin pigment 100,000 Melitoxin Dicumarol Anticoagulant 100,000 Mellaril Thioridazine Antipsychotic 100,000 Menocil Aminorex Anorexic 100,000 Menocil metabolite (Euphoria) Aminorex metab.(Methylaminorex, 4-) Anorexic metabolite 100,000 Menthol Menthol Flavoring 100,000 Merbentul Chlorotrianisene Estrogen 100,000 Meridia Sibutramine Anorexic 100,000 Merital Nomifensine Antidepressant 100,000 Mersalin Mersalyl acid Diuretic 100,000 Merthiolate Thimerosal Anti-infective 1,000,000 Mesantoin Mephenytoin Anticonvulsant 100,000 Mesantoin metabolite Mephenytoin metab.(Hydroxymephenytoin, 4-) Mephenytoin metabolite 100,000 Mestinon Pyridostigmine Cholinergic 100,000 Methcathinone Methylamino-propiophenone, 2- Amphetamine-like 100,000 Methenolone Methenolone Anabolic 100,000 Metheph Methylephedrine, N-(1R,2S)-(-) Analeptic 100,000 Metheph Methylephedrine, N-(1S,2R)-(+) Analeptic 100,000 Metheph Methylpseudoephedrine, N-(1R,2R)-(-) Analeptic 100,000 Metheph Methylpseudoephedrine, N-(1S,2S)-(+) Analeptic 100,000 Methylene blue Methylene blue Antimethemoglobinemic 10,000 Methylene chloride Dichloromethane Solvent 500,000 Metofane Methoxyflurane Anesthetic 1,000,000 Mexamin Methoxytryptamine, 5- Hypnotic potentiator 100,000 Mexitil Mexiletine Antiarrhythmic 100,000 Midamor Amiloride Diuretic 100,000

Sources: 1. Merck Index 2. Disposition of Toxic Drugs and Chemicals in Man 3. Physicians Desk Reference 2000 Rev.A 10-8-2002 TOX Specificity-Trade Name Biosite Inc. Page 43

Highest Conc. Tested Conc. Giving Positive TRADE NAME CHEMICAL NAME DRUG CLASS (ng/ml) (ng/ml) Midrin Isometheptene Adrenergic 100,000 MeAMP 100,000 Midrin Dichloralphenazone Sedative 100,000 Mikedimide Bemegride Analeptic 100,000 Milontin Phensuximide Anticonvulsant 500,000 Miltown Meprobamate Sedative 100,000 Minipress Prazosin Antihypertensive 100,000 Miolene Ritodrine Tocolytic 100,000 Moderil Rescinnamine Antihypertensive 500,000 Mogadon Nitrazepam Benzodiazepine 100,000 BZO 2,600 Mogadon metabolite Nitrazepam metab.(2-Amino-5-Nitrobenzophenone) Benzodiazepine metabolite 100,000 Monopril Fosinopril ACE inhibitor 100,000 Morphine metabolite Morphine 3-ß-glucuronide Morphine metabolite 100,000 OPI 450 Morphine metabolite Morphine metab.(Normorphine) Narcotic analgesic 300,000 OPI 200,000 Morphine Morphine Narcotic analgesic 100,000 OPI 300 Motilium Domperidone Antiemetic 100,000 Motrin Ibuprofen Anti-inflammatory 1,000,000 Mucomyst Acetyl-l-cysteine, N- Mucolytic 100,000 Myambutol Ethambutol Antibacterial 100,000 Myanesin Mephenesin Muscle relaxant 100,000 Myocholine Bethanechol Cholinergic 100,000 Mysoline Primidone Anticonvulsant 100,000 Mysoline metabolite Primidone metab.(Ethyl-2-phenylmalonamide, 2-) Primidone metabolite 100,000 Nafcil Nafcillin Antibacterial 100,000 Nalfon Fenoprofen Anti-inflammatory 100,000 Nandrolone Nortestosterone, 19- Anabolic Steroid 100,000 Naphcon Naphazoline Adrenergic 100,000 Naprosyn Naproxen Anti-inflammatory 100,000 Narcan Naloxone Narcotic antagonist 300,000 OPI 200,000 Narcosine Noscapine Antitussive 100,000 Nardil Phenelzine Antidepressant 1,000,000 Nasalide Flunisolide Glucocorticoid 100,000 Navane Thiothixene Antipsychotic 100,000 Neantine Phthalic acid Organic solvent 100,000 THC 25,000 Nebcin Tobramycin Antibacterial 100,000

Sources: 1. Merck Index 2. Disposition of Toxic Drugs and Chemicals in Man 3. Physicians Desk Reference 2000 Rev.A 10-8-2002 TOX Specificity-Trade Name Biosite Inc. Page 44

Highest Conc. Tested Conc. Giving Positive TRADE NAME CHEMICAL NAME DRUG CLASS (ng/ml) (ng/ml) Negram Nalidixic acid Antibacterial 1,000,000 Nembutal Pentobarbital Barbiturate 100,000 BAR 300 Neomin Neomycin Antibacterial 200,000 Neo-Synephrine Phenylephrine Decongestant 100,000 Neoxin Isoniazid Antibacterial 100,000 Neptazane Methazolamide Diuretic 100,000 Nerisona Diflucortolone Anti-inflammatory 100,000 Neurontin Gabapentin Anticonvulsant 100,000 Niamid Nialamide Antidepressant 100,000 Nicarpin Nicardipine Antianginal 100,000 Nicotine Nicotine Vasoconstrictor 1,000,000 THC 200,000 Nicotine metabolite Nicotine metab.(Cotinine, l-) Antidepressant 100,000 Nidrel Nitrendipine Antihypertensive 100,000 Nikardin Nikethamide Stimulant 100,000 Nilevar Norethandrolone Androgen 100,000 Nisentil Alphaprodine Narcotic analgesic 100,000 Nizoral Ketoconazole Antifungal 100,000 Nobrium Medazepam Benzodiazepine 100,000 BZO 32,000 Noludar Methyprylon Sedative 100,000 Nolvadex Tamoxifen Antiestrogen 100,000 Nordaz Nordiazepam Benzodiazepine 100,000 BZO 700 Norden Octopamine Adrenergic 100,000 Norflex Orphenadrine Antihistamine 1,000,000 Norisodrine Isoproterenol, d,l- Bronchodilator 100,000 Normetazocine Normetazocine Metazocine metabolite 100,000 Normodyne Labetalol Antihypertensive 1,000,000 Normodyne metabolite Labetalol metab.(3-Amino-1-Phenylbutane) Labetalol metabolite 1,000,000 Noroxcin Norfloxacin Antibacterial 100,000 Norpace Disopyramide Antiarrhythmic 200,000 Norpramine Desipramine Tricyclic antidepressant 100,000 TCA 1,000 Norval Mianserin Antidepressant 100,000 Notensil Acetopromazine Tranquilizer 100,000 Novacain Procaine Anesthetic 100,000 Novicet Vincamine Vasodilator 100,000

Sources: 1. Merck Index 2. Disposition of Toxic Drugs and Chemicals in Man 3. Physicians Desk Reference 2000 Rev.A 10-8-2002 TOX Specificity-Trade Name Biosite Inc. Page 45

Highest Conc. Tested Conc. Giving Positive TRADE NAME CHEMICAL NAME DRUG CLASS (ng/ml) (ng/ml) Nubain Nalbuphine Narcotic analgesic 1,000,000 Numorphan Oxymorphone Narcotic analgesic 100,000 OPI 41,000 Numorphan metabolite Oxymorphone metab.(Noroxymorphone) Oxymorphone metabolite 300,000 Nupercaine Dibucaine Anesthetic 1,000,000 THC 100,000 Nutrasweet Aspartame Sweetener 100,000 Obesin Propylhexedrine Decongestant 100,000 Octalene Aldrin Insecticide 100,000 Ogen Estrone-3-sulfate Estrogen 100,000 Oil of wintergreen Methyl salicylate Counterirritant 5,000,000 Opiran Pimozide Antipsychotic 100,000 Organoderm Malathion Insecticide 1,000,000 Orinase Tolbutamide Antidiabetic 100,000 Orisulf Sulfaphenazole Antibacterial 100,000 Orotyl Orotic acid Uricosuric 100,000 Orsin Phenylenediamine, p- Dye 200,000 Orudis Ketoprofen Analgesic 1,000,000 Oxalic acid Oxalic acid Hemostatic agent 10,000,000 Oxandrolone Oxandrolone Androgen 100,000 Oxilin Oxymetazoline Adrenergic 100,000 Oxycontin Oxycodone Narcotic analgesic 100,000 OPI 23,000 Oxycyclin Oxytetracycline Antibacterial 100,000 PABA para-Aminobenzoic acid Ultraviolet screen 200,000 Palerol Dipyrone Analgesic 100,000 Pamelor Nortriptyline Tricyclic antidepressant 100,000 TCA 1,100 Pamelor metabolite Nortriptyline metabolite (+/- E-10-hydroxylated) Nortriptyline metabolite 100,000 TCA 750 Pamelor metabolite Nortriptyline metabolite (+/- Z-10-hydroxylated) Nortriptyline metabolite 100,000 TCA 5,000 Paracetamol Acetaminophen Analgesic 1,000,000 Paradione Paramethadione Anticonvulsant 100,000 Paraflex Chlorzoxazone Muscle relaxant 1,000,000 Paraflu Flufenamic acid Anti-inflammatory 100,000 Paral Paraldehyde Sedative 1,000,000 Paramorphine Thebaine Opiate 100,000 OPI 24,000 para-Nitrophenol para-Nitrophenol Dye 100,000 Paraplatin Carboplatin Antineoplastic 100,000

Sources: 1. Merck Index 2. Disposition of Toxic Drugs and Chemicals in Man 3. Physicians Desk Reference 2000 Rev.A 10-8-2002 TOX Specificity-Trade Name Biosite Inc. Page 46

Highest Conc. Tested Conc. Giving Positive TRADE NAME CHEMICAL NAME DRUG CLASS (ng/ml) (ng/ml) Paredrine Amphetamine analog(Hydroxyamphetamine, p-) Amphetamine analog 200,000 AMP 20,000 Parlodel Bromoergocryptine, 2-a- Antiparkinsonian 100,000 Parnate Tranylcypromine Antidepressant 100,000 Pastaron Urea Diuretic 60,000,000 Pavabid Papaverine Relaxant 100,000 Pavulon Pancuronium Muscle relaxant 100,000 Paxil Paroxetine Antidepressant 100,000 THC 20,000 Paxipam Halazepam Benzodiazepine 100,000 BZO 100 PCP analog PCA (1-Phenylcyclohexylamine) PCP analog 100,000 PCP analog PCC (1-Piperidinocyclohexane Carbonitrile) PCP analog 100,000 PCP analog PCE (n-Ethyl-1-Phenylcyclohexylamine) PCP analog 100,000 PCP 5,000 PCP analog PCPy (1-(1-Phenylcyclohexyl)-pyrrolidine) PCP analog 100,000 PCP 400 PCP analog TCM (1-[1-(2-Thienyl)cyclohexyl]-morpholine) PCP analog 100,000 PCP 10,000 PCP analog TCP (1-[1-(2-Thienyl)cyclohexyl]-piperidine) PCP analog 300,000 PCP analog TCPy (1-[1-(2-Thienyl)cyclohexyl]-pyrrolidine) PCP analog 100,000 PCP 250 PCP metabolite PCP metab.(Hydroxy PCP, 4-) PCP metabolite 100,000 PCP 25,000 PCP/Angel dust PCP/Phencyclidine PCP 100,000 PCP 25 PDG Pregnanediol glucuronide (PDG) Estrogen 100,000 PEA Phenethylamine, B- Amphetamine analog 1,000,000 AMP 40,000 Peganone Ethotoin Anticonvulsant 100,000 Pentothal Thiopental Anesthetic/Barbiturate 100,000 Pepcid Famotidine Anti-ulcerative 100,000 Percodan Oxycodone Narcotic analgesic 100,000 OPI 23,000 Peremine Histamine Diagnostic aid 1,000,000 Peremine metabolite Histamine metab.(Imidazole-4-acetic acid) Histamine metabolite 200,000 Peremine metabolite Histamine metab.(Methyl histamine, 1-) Histamine metabolite 100,000 Periactin Cyproheptadine Antihistamine 1,000,000 Permax Pergolide Antiparkinsonian 100,000 Persantine Dipyridamole Coronary vasodilator 100,000 Pethidine Meperidine Narcotic analgesic 100,000 Pethidine metabolite Meperidine metab.(Normeperidine) Meperidine metabolite 100,000 Peyote Mescaline Hallucinogen 100,000 Phanurane Canrenoic acid Diuretic 100,000 Phenergan Promethazine Antihistaminic 100,000

Sources: 1. Merck Index 2. Disposition of Toxic Drugs and Chemicals in Man 3. Physicians Desk Reference 2000 Rev.A 10-8-2002 TOX Specificity-Trade Name Biosite Inc. Page 47

Highest Conc. Tested Conc. Giving Positive TRADE NAME CHEMICAL NAME DRUG CLASS (ng/ml) (ng/ml) Phenoverm Phenothiazine Anthelmintic 100,000 Phenylacetone Phenylacetone Organic synthesis 100,000 Phenylalanine, d,l- Phenylalanine, dl- Amino Acid 100,000 Phenylenediamine, m- Phenylenediamine, m- Dye 200,000 Phenylmethanol Benzyl alcohol Antimicrobial 1,000.00 Phisohex Hexachlorophene Anti-infective 100,000 Phrenilin Butalbital Barbiturate 100,000 BAR 150 Pima syrup Potassium iodide Iodine supplement 200,000 Pindac Pinacidil Antihypertensive 100,000 Pipram Pipemidic acid Antibacterial 1,000,000 Pirodal Piromidic acid Antibacterial 1,000,000 Pitocin Oxytocin Pituitary Hormone 100,000 Placidyl Ethchlorvynol Sedative 100,000 Plavix Clopidrogrel Antiplatelet aggregation factor 100,000 Polocaine Mepivacaine Anesthetic 1,000,000 Poly-Histine Pheniramine Antihistamine 100,000 Poly-Histine Phenyltoloxamine Antihistamine 1,000,000 Pondex Pemoline CNS stimulant 100,000 Pondimin Fenfluramine Anorexic 100,000 MeAMP 40,000 Pondimin metabolite Fenfluramine metab.(Trifluoromethylbenzoic acid, m-) Fenfluramine metabolite 100,000 Ponstel Mefenamic acid Anti-inflammatory 100,000 Potassium nitrite Potassium nitrite Vasodialator 1,000,000 Potassium phosphate Potassium phosphate, dibasic Buffering agent 1,000,000 Prednisolone Prednisolone Glucocorticoid 100,000 Pregnenolone Progesterone metab.(Pregnen-3ß-ol-20-one, delta 5-) Progesterone metabolite 100,000 Preludin Phenmetrazine Anorexic 100,000 MeAMP 90,000 Previcid Lansoprazole Anti-ulcerative 100,000 Prilosec Omeprazole Anti-ulcerative 100,000 Primacor Milrinone Cardiotonic 100,000 Primaquine Primaquine Antimalarial 100,000 Prinivil Lisinopril Antihypertensive 100,000 Proaqua Benzthiazide Diuretic 100,000 Proasma Methoxyphenamine Bronchodilator 100,000 Procardia Nifedipine Antianginal 100,000

Sources: 1. Merck Index 2. Disposition of Toxic Drugs and Chemicals in Man 3. Physicians Desk Reference 2000 Rev.A 10-8-2002 TOX Specificity-Trade Name Biosite Inc. Page 48

Highest Conc. Tested Conc. Giving Positive TRADE NAME CHEMICAL NAME DRUG CLASS (ng/ml) (ng/ml) Prolixin Fluphenazine Antipsychotic 100,000 Prometrium Progesterone Progestogen 100,000 Pronestyl Procainamide Antiarrhythmic 100,000 Pronestyl metabolite Procainamide metab.(N-Acetylprocainamide) Procainamide metabolite 100,000 Prontosil Sulfanilamide Antibacterial 100,000 Propulsid Cisapride Peristaltic stimulant 100,000 THC 60,000 Propylamphetamine Propylamphetamine Amphetamine analog 100,000 Propylbenzene Propylbenzene Solvent 1,000,000 ProSom Estazolam Benzodiazepine 100,000 BZO 300 Prothiaden Dothiepin Tricyclic Antidepressant 100,000 TCA 1,000 Protonix Pantoprazole Anti-ulcerative 1,000,000 THC 750,000 Protopam Pralidoxime Cholinesterase reactivator 100,000 Proventil Albuterol Bronchodilator 200,000 Prozac Fluoxetine Antidepressant 100,000 Prozac metabolite Fluoxetine metab.(Norfluoxetine) Prozac metabolite 100,000 Psilocin Psilocin Psilocybin metabolite 100,000 Psilocybin Psilocybin Hallucinogen 100,000 Putrescine Putrescine Neurotransmitter precursor 100,000 Pyribenzamine Tripelennamine Antihistamine 100,000 Pyridium Phenazopyridine Analgesic 100,000 Quaalude Methaqualone Hypnotic 100,000 Quiniglute Quinidine Antiarrhythmic 100,000 Quinine Quinine Antimalarial 100,000 Rauwolfia Rauwolfia serpentina Antihypertensive 1,000,000 Redeptin Fluspirilene Neuroleptic 100,000 Reglan Metoclopramide Peristaltic stimulant 1,000,000 Regletin Alprenolol Antiarrhythmic 200,000 Reglone Diquat Herbicide 10,000 Relafen Nabumetone Anti-inflammatory 100,000 Remeron Mirtazepine Antipsychotic 1,000,000 Reserpex Reserpine Antihypertensive 100,000 Restoril Temazepam Benzodiazepine 100,000 BZO 200 Restoril metabolite Temazepam glucuronide Benzodiazepine metabolite 10,000 BZO 1,000 Retrovir Zidovudine/AZT Antiviral 1,000,000

Sources: 1. Merck Index 2. Disposition of Toxic Drugs and Chemicals in Man 3. Physicians Desk Reference 2000 Rev.A 10-8-2002 TOX Specificity-Trade Name Biosite Inc. Page 49

Highest Conc. Tested Conc. Giving Positive TRADE NAME CHEMICAL NAME DRUG CLASS (ng/ml) (ng/ml) Revex Nalmefene Narcotic antagonist 100,000 ReVia Naltrexone Narcotic antagonist 100,000 Rheumatrex Methotrexate Antineoplastic 2,000,000 Rifadin Rifampin Antibiotic 100,000 Rimcazole Rimcazole Antipsychotic 100,000 Risperdal Risperidone Antipsychotic 100,000 Risperdal metabolite Risperidone, 9-OH- Risperidone metabolite 100,000 Ritalin Methylphenidate Stimulant 1,000,000 Robaxin Methocarbamol Relaxant 1,000,000 Robitussin Guaiphenesin/Guaiacol glyceryl ether Expectorant 1,000,000 Rocefin Ceftriaxone Antibacterial 100,000 Rogaine Minoxidil Antialopecia agent 100,000 Rogitine Phentolamine Antihypertensive 100,000 Rohypnol Flunitrazepam Benzodiazepine 100,000 BZO 150 Rohypnol metabolite Flunitrazepam metab.(7-Aminoflunitrazepam) Benzodiazepine 100,000 BZO 7,500 Romazicon Flumazenil Benzodiazepine antagonist 100,000 Romazicon metabolite Flumazenil metabolite Flumazenil metabolite 100,000 Romilar Dextromethorphan Antitussive/Opiate 5,000,000 OPI 5,000,000 Romilar metabolite Dextromethorphan metab.(Dextrorphan,d-) Dextromethorphan metab. 100,000 Romilar metabolite Dextromethorphan metab.(Hydroxymorphinan, 3-) Dextromethorphan metab. 100,000 Romilar metabolite Dextromethorphan metab.(Methoxymorphinan, 3-) Dextromethorphan metab. 100,000 Roxicet metabolite Morphine 3-ß-glucuronide Morphine metabolite 100,000 OPI 450 Roxicet metabolite Morphine metab.(Normorphine) Narcotic analgesic 300,000 OPI 200,000 Roxicet Morphine Narcotic analgesic 100,000 OPI 300 Rynatan Azatadine Antihistaminic 100,000 Salagen Pilocarpine Antiglaucoma 100,000 Salt Sodium chloride Electrolyte replenisher 60,000,000 Samiac Ammonium chloride Expectorant 200,000 Sandimmune Cyclosporin A Immunosuppressant 100,000 Sanorex Mazindol Anorexic 200,000 Santobrite Pentachlorophenol Insecticide 100,000 Scotine Cotinine, l- Antidepressant 100,000 Seconal Secobarbital Barbiturate 100,000 BAR 300 Sectral Acebutolol Antihypertensive 100,000

Sources: 1. Merck Index 2. Disposition of Toxic Drugs and Chemicals in Man 3. Physicians Desk Reference 2000 Rev.A 10-8-2002 TOX Specificity-Trade Name Biosite Inc. Page 50

Highest Conc. Tested Conc. Giving Positive TRADE NAME CHEMICAL NAME DRUG CLASS (ng/ml) (ng/ml) Seldane Terfenadine Antihistamine 100,000 Sensorcaine Bupivacaine Anesthetic 1,000,000 Septra Sulfamethoxazole Antibacterial 1,000,000 Septra Trimethoprim Antibacterial 100,000 Serax Oxazepam Benzodiazepine 100,000 BZO 3,500 Serax metabolite Oxazepam glucuronide Benzodiazepine metabolite 10,000 BZO 1,100 Serefrex Ketanserin Antihypertensive 100,000 Serenal Oxazolam Benzodiazepine 100,000 Serentil Mesoridazine Antipsychotic 1,000,000 Seroquel Quetiazepine Antipsychotic 100,000 Serzone Nefazadone Antidepressant 100,000 Serzone metabolite Nefazadone metab.(Piperazine, 1-(3-chlorophenyl)-) Serzone metabolite 100,000 Sinemet Carbidopa Antiparkinsonian 1,000,000 Sinequan Doxepin Tricyclic antidepressant 100,000 TCA 1,300 Sinequan metabolite Doxepin metab.(Nordoxepin) Doxepin metabolite 100,000 TCA 1,500 Singulair Montelukast Anti-asthmatic 100,000 Sodium borate Sodium borate Antiseptic 100,000 Sodium formate Sodium formate Astringent 100,000 Sodium nitrite Sodium nitrite Food preservative 2,000,000 Sodium phosphate Sodium phosphate, dibasic Cathartic 1,000,000 Solian Amisulpiride Antipsychotic 1,000,000 Soma Carisoprodol Muscle relaxant 100,000 Somnos Chloral hydrate Hypnotic 100,000 Somnos metabolite Chloral hydrate metab.(Trichloroethanol) Chloral hydrate metabolite 100,000 Somnurol Bromisovalum Sedative 5,000,000 Soneryl Butethal Barbiturate 100,000 BAR 50 Sorbol Sorbital Laxative 100,000 Sparine Promazine Antipsychotic 100,000 Spectracide Diazinon Insecticide 100,000 Spiropent Clenbuterol Antiasthmatic 100,000 Stadol Butorphanol Narcotic analgesic 100,000 Stelazine Trifluoperazine Antipsychotic 100,000 Steranabol Chlorotestosterone, 4- 17-acetate Anabolic steroid 100,000 Stiedex Desoximetasone Anti-inflammatory 100,000

Sources: 1. Merck Index 2. Disposition of Toxic Drugs and Chemicals in Man 3. Physicians Desk Reference 2000 Rev.A 10-8-2002 TOX Specificity-Trade Name Biosite Inc. Page 51

Highest Conc. Tested Conc. Giving Positive TRADE NAME CHEMICAL NAME DRUG CLASS (ng/ml) (ng/ml) Strychnine Strychnine Stimulant 100,000 Sublimaze Fentanyl Narcotic analgesic 100,000 Sublimaze metabolite Fentanyl metab.(Despropionyl fentanyl) Fentanyl metabolite 10,000 Sublimaze metabolite Fentanyl metab.(Norfentanyl) Fentanyl metabolite 10,000 Succaryl Saccharin Non-caloric sweetener 10,000,000 Sudafed Pseudoephedrine, d- Decongestant 1,000,000 Sudafed Pseudoephedrine, l- Pseudoephedrine isomer 1,000,000 Sudafed metabolite Pseudoephedrine metab.(Norpseudoephedrine, d-) Pseudoephedrine metabolite 1,000,000 Sudafed metabolite Pseudoephedrine metab.(Norpseudoephedrine, l-) Pseudoephedrine metabolite 100,000 Sulfadiazine Sulfadiazine Antibacterial 100,000 Sulfaguine Sulfaguanidine Antibacterial 100,000 Sulfoxol Sulfisoxazole Antibacterial 100,000 Surital Thiamylal Anesthetic 100,000 BAR 40,000 Surmontil Trimipramine Tricyclic antidepressant 100,000 TCA 3,000 Survector Amineptine CNS Stimulant 100,000 Symmetrel Amantadine Antiviral 100,000 Synalgos Dihydrocodeine Narcotic analgesic 300,000 OPI 250 Synapause Estriol Estrogen 100,000 Tagamet Cimetidine Antiulcerative 1,000,000 Talwin Pentazocine Narcotic analgesic 300,000 Tandearil Oxyphenbutazone Anti-inflammatory 100,000 Tannin Tannic acid Astringent 100,000 Taractan Chlorprothixene Antipsychotic 100,000 Taxilan Perazine Antipsychotic 100,000 Taxol Taxol Antineoplastic 100,000 Tegretol Carbamazepine Anticonvulsant 100,000 THC 10,000 Tegretol metabolite Carbamazepine metab.(Iminostilbene) Carbamazepine metabolite 100,000 Tegretol metabolite Carbamazepine, 10,11-Dihydroxy- Carbamazepine metabolite 100,000 THC 60,000 Tegretol metabolite Carbamazepine-10,11-epoxide Carbamazepine metabolite 100,000 Tenormin Atenolol Antihypertensive 100,000 Tenuate Diethylpropion Anorexic 100,000 Tequin Gatifloxacin Antibiotic 5,000,000 Tessalon Benzonatate Antitussive 1,000,000 Testoral Fluoxymesterone Androgen 100,000

Sources: 1. Merck Index 2. Disposition of Toxic Drugs and Chemicals in Man 3. Physicians Desk Reference 2000 Rev.A 10-8-2002 TOX Specificity-Trade Name Biosite Inc. Page 52

Highest Conc. Tested Conc. Giving Positive TRADE NAME CHEMICAL NAME DRUG CLASS (ng/ml) (ng/ml) Testred Methyltestosterone, 17-a- Androgen 100,000 THC THC(Cannabidiol) Cannabinoid 100,000 THC THC(Cannabinol) Cannabinoid 100,000 THC 20,000 THC THC(Cannabinol, D8-) Cannabinoid 200,000 THC 5,000 THC THC, 11-nor-9-carboxy-D8- Cannabinoid 100,000 THC 4,000 THC THC, l-11-Hydroxy-D9- Cannabinoid 10,000 THC 10,000 THC THC, l-11-nor-9-carboxy-D9- Cannabinoid 10,000 THC 50 THC THC, l-11-nor-9-carboxy-D9-glucuronide Cannabinoid metabolite 1,000 THC 50 THC/Marinol THC(Cannabinol, D9-) Cannabinoid 1,000,000 THC 40,000 Thorazine Chlorpromazine Antipsychotic 100,000 Thyme camphor Thymol Antiseptic 100,000 Tiazac Diltiazem Antianginal/Antiarrhythmic 1,000,000 Ticlid Ticlopidine Antiplatelet aggregation factor 1,000,000 Tigan Trimethobenzamide Antiemetic 1,000,000 Tilcotil Tenoxicam Anti-inflammatory 100,000 Timolide Timolol Antihypertensive 100,000 TMP Trimethoprim Antibacterial 100,000 Tofranil Imipramine Tricyclic antidepressant 100,000 TCA 600 Tolectin Tolmetin Anti-inflammatory 100,000 Tolfedine Tolfenamic acid Anti-inflammatory analgesic 1,000,000 Tolinase Tolazamide Antidiabetic 100,000 Toluene Toluene Organic solvent 100,000 Tonocard Tocainide Antiarrhythmic 100,000 Toradol Ketorolac tromethamine Analgesic 100,000 Tracazolate Tracazolate Anxiolytic 100,000 Tramal Tramadol Analgesic 1,000,000 Tramal metabolite Tramadol M-1 metabolite Tramadol metabolite 1,000,000 Trancopal Chlormezanone Anxiolytic 100,000 Trandate Labetalol Antihypertensive 1,000,000 Trandate metabolite Labetalol metab.(3-Amino-1-Phenylbutane) Labetalol metabolite 1,000,000 Tranvet Propionylpromazine Tranquilizer 100,000 Tranxene Clorazepate Benzodiazepine 100,000 BZO 1,600 Tremblex Dexetimide Anticholinergic 100,000 Trental Pentoxifylline Vasodilator 100,000

Sources: 1. Merck Index 2. Disposition of Toxic Drugs and Chemicals in Man 3. Physicians Desk Reference 2000 Rev.A 10-8-2002 TOX Specificity-Trade Name Biosite Inc. Page 53

Highest Conc. Tested Conc. Giving Positive TRADE NAME CHEMICAL NAME DRUG CLASS (ng/ml) (ng/ml) Triaminic Pyrilamine Antihistamine 100,000 Tridone Trimethadione Anticonvulsant 100,000 Trihistan Chlorcyclizine Antihistamine 100,000 Trilafon Perphenazine Antipsychotic 100,000 Trinalin Azatadine Antihistaminic 100,000 Tropicamide Tropicamide Anticholinergic 100,000 Tryptamine Tryptamine Amino acid 100,000 Tubadil Tubocurarine Muscle relaxant 100,000 Tuxi Pholcodine Antitussive/Opiate 100,000 OPI 400 Tylenol Acetaminophen Analgesic 1,000,000 Tyrimide Isopropamide Anticholinergic 100,000 Tyrosine, d,l- Tyrosine, d,l- Amino acid 1,000,000 Ultram Tramadol Analgesic 1,000,000 Ultram metabolite Tramadol M-1 metabolite Tramadol metabolite 1,000,000 Unisom Doxylamine Antihistamine/ Sedative 100,000 Urecholine Carbamyl-ß-methylcholine chloride Cholinergic 200,000 Uric acid Uric acid Urine component 100,000 Urinox Oxolinic acid Antibacterial 100,000 Urised Benzoic acid Antifungal 100,000 Urised/Urex/Uroquid Methenamine Antibacterial 200,000 Uteramin Tyramine Adrenergic 1,000,000 AMP 200,000 Validex Ifenprodil Vasodilator 100,000 Valium Diazepam Benzodiazepine 100,000 BZO 200 Vallergan Trimeprazine Antipruritic 100,000 Valmid Ethinamate Sedative 100,000 Vanceril Beclomethasone Antiasthmatic 1,000,000 Vancocin Vancomycin Antibacterial 100,000 Vasotec Enalapril Antihypertensive 100,000 Vasylox Methoxamine Adrenergic 100,000 Vegolysen Hexamethonium Antihypertensive 100,000 Ventolin Albuterol Bronchodilator 200,000 VePesid Etoposide Antineoplastic 100,000 Vermicidin Mebendazole Anthelmintic 100,000 Versed Midazolam Benzodiazepine 100,000 BZO 300

Sources: 1. Merck Index 2. Disposition of Toxic Drugs and Chemicals in Man 3. Physicians Desk Reference 2000 Rev.A 10-8-2002 TOX Specificity-Trade Name Biosite Inc. Page 54

Highest Conc. Tested Conc. Giving Positive TRADE NAME CHEMICAL NAME DRUG CLASS (ng/ml) (ng/ml) Versed metabolite Midazolam metab.(a-Hydroxymidazolam) Benzodiazepine metabolite 10,000 BZO 200 Vesadin Sulfamethazine Antibacterial 100,000 Vetame Triflupromazine Antipsychotic 100,000 Viagra Sildenafil Treat erectile dysfuntion 100,000 Vialin Mephentermine Adrenergic 300,000 MeAMP 30,000 Vibramycin Doxycycline Antibacterial 1,000,000 Vicks Inhaler Methamphetamine, l- OTC decongestant 100,000 MeAMP 30,500 Vicodin Hydrocodone Antitussive/Narcotic analgesic 100,000 OPI 1,700 Vioxx Rofecoxib Anti-imflammatory 100,000 Visine Tetrahydrozyline Adrenergic 100,000 Visken Pindolol Antihypertensive 100,000 Vitamin B1 Thiamine Vitamin 100,000 Vitamin B-12 Hydroxocobalamin Hematopoietic vitamin 100,000 vitamin B2 Riboflavin Vitamin 75,000 Vitamin B3 Nicotinamide/Niacin Vitamin (enzyme cofactor) 100,000 Vitamin B3 Nicotinic acid/Niacin Vitamin (enzyme cofactor) 1,000,000 Vitamin B3 metabolite Nicotinic acid metab.(Hydroxynicotinic acid, 6-) Vitamin metabolite 200,000 Vitamin B6 Pyridoxine Vitamin 200,000 Vitamin C Ascorbic acid Vitamin 1,500,000 Vitamin K1 Phylloquinone Prothrombogenic vitamin 100,000 Vivactil Protriptyline Tricyclic antidepressant 100,000 TCA 3,300 Voltaren Diclofenac Anti-inflammatory 1,000,000 Wellbutrin Bupropion Antidepressant 1,000,000 Wellbutrin metabolite Bupropion metabolite Antidepressant 100,000 Welldorm Dichloralphenazone Sedative 100,000 Winstrol Stanozolol Androgen 100,000 Wood alcohol Methanol Solvent 10,000,000 Wytensin Guanabenz Antihypertensive 100,000 THC 20,000 Xanax Alprazolam Benzodiazepine 100,000 BZO 100 Xanax metabolite Alprazolam, 4-Hydroxy- Benzodiazepine metabolite 100,000 BZO 250 Xanax metabolite Alprazolam-glucuronide, a-Hydroxy Benzodiazepine metabolite 5,000 BZO 150 Xanax metabolite Alprazolam, a-Hydroxy- Benzodiazepine metabolite 100,000 BZO 50 Xylocaine Lidocaine Anesthetic 100,000 Xymelin Xylometazoline Adrenergic 100,000

Sources: 1. Merck Index 2. Disposition of Toxic Drugs and Chemicals in Man 3. Physicians Desk Reference 2000 Rev.A 10-8-2002 TOX Specificity-Trade Name Biosite Inc. Page 55

Highest Conc. Tested Conc. Giving Positive TRADE NAME CHEMICAL NAME DRUG CLASS (ng/ml) (ng/ml) Yohimex Yohimbine Mydriatic 200,000 Zantac Ranitidine Anti-ulcerative 500,000 Zarontin Ethosuximide Anticonvulsant 1,000,000 BAR 750,000 Zaroxolyn Metolazone Diuretic 100,000 Zearalenone Zearalenone Anabolic 100,000 THC 60,000 Zelmid Zimeldine Antidepressant 100,000 Zestril Lisinopril Antihypertensive 100,000 Zocor Simvastatin Antihyperlipidemic 100,000 THC 60,000 Zoloft Sertraline Antidepressant 100,000 Zoloft metabolite Sertraline metab.(Desmethylsertraline) Sertraline metabolite 100,000 Zomax Zomepirac Analgesic 100,000 Zostrix Capsaicin Topical analgesic 100,000 Zyban Bupropion Antidepressant 1,000,000 Zyban metabolite Bupropion metabolite Antidepressant 100,000 Zyloprim Allopurinol Antiurolithic 100,000 Zyprexa Olanzapine Antipsychotic 100,000

Sources: 1. Merck Index 2. Disposition of Toxic Drugs and Chemicals in Man 3. Physicians Desk Reference 2000 Rev.A 10-8-2002 TOX Specificity-Drug Class Biosite Inc. Page 56

AMPHETAMINE

Highest Conc. Tested Conc. Giving Positive TRADE NAME CHEMICAL NAME DRUG CLASS (ng/ml) (ng/ml) Adderall/Dexedrine/Benzadrine Amphetamine, d- Amphetamine 100,000 AMP 1,000 Cydril Amphetamine, l- Amphetamine 100,000 AMP 63,500 Paredrine Amphetamine analog(Hydroxyamphetamine, p-) Amphetamine analog 200,000 AMP 20,000 BDB BDB(d,l-1-(3,4-Methylenedioxyphenyl)-2-Butanamine) MBDB metabolite 100,000 AMP 2,500 Chloroamphetamine, 4- Chloroamphetamine, 4- Amphetamine 200,000 AMP 2,300 MDA MDA (3,4-Methylenedioxyamphetamine) Amphetamine analog 100,000 AMP 3,700 PEA Phenethylamine, B- Amphetamine analog 1,000,000 AMP 40,000 Death PMA (paraMethoxyamphetamine) Amphetamine analog 100,000 AMP 2,500 Uteramin Tyramine Adrenergic 1,000,000 AMP 200,000

METHAMPHETAMINE

Highest Conc. Tested Conc. Giving Positive TRADE NAME CHEMICAL NAME DRUG CLASS (ng/ml) (ng/ml) Amphetamine analog Amphetamine analog(Ethylamphetamine, N-) Amphetamine analog 100,000 MeAMP 12,500 Ephedrine Ephedrine, l- Bronchodilator 10,000,000 MeAMP 400,000 Pondimin Fenfluramine Anorexic 100,000 MeAMP 40,000 Midrin Isometheptene Adrenergic 100,000 MeAMP 100,000 MBDB MBDB(d,l-Methyl-1(3,4-Methylenedioxyphenyl)2-Butanamine) MDMA analog 100,000 MeAMP 800 Eve MDEA (3,4-Methylenedioxethylamphetamine) Amphetamine analog 100,000 MeAMP 4,600 Ecstasy MDMA (3,4-Methylenedioxymethamphetamine) Amphetamine analog 100,000 MeAMP 1,500 Vialin Mephentermine Adrenergic 300,000 MeAMP 30,000 Desoxyn/Speed/Ice/Crystal Methamphetamine, d- Amphetamine 100,000 MeAMP 1,000 Vicks Inhaler Methamphetamine, l- OTC decongestant 100,000 MeAMP 30,500 Desoxyn metabolite Methamphetamine metab.(Hydroxy methamphetamine, p-) Methamphetamine metabolite 100,000 MeAMP 2,500 Preludin Phenmetrazine Anorexic 100,000 MeAMP 90,000

Sources: 1. Merck Index 2. Disposition of Toxic Drugs Chemicals in Man 3. Physicians Desk Reference 2000 Rev.A 10-8-2002 TOX Specificity-Drug Class Biosite Inc. Page 57

BARBITURATES

Highest Conc. Tested Conc. Giving Positive TRADE NAME CHEMICAL NAME DRUG CLASS (ng/ml) (ng/ml) Diadol Allobarbital Barbiturate 100,000 BAR 150 Amytal Amobarbital Barbiturate 100,000 BAR 100 Alurate Aprobarbital Barbiturate 100,000 BAR 200 Barbitone Barbital Barbiturate 100,000 BAR 150 Butisol Butabarbital Barbiturate 100,000 BAR 200 Fiorinal/Phrenilin Butalbital Barbiturate 100,000 BAR 150 Soneryl Butethal Barbiturate 100,000 BAR 50 Cyclopal Cyclopentobarbital Barbiturate 100,000 BAR 100 Zarontin Ethosuximide Anticonvulsant 1,000,000 BAR 750,000 Doriden Glutethimide, d,l- Sedative 100,000 BAR 50,000 Mebaral Mephobarbital Barbiturate 100,000 BAR 20,000 Gemonil Metharbital Anticonvulsant/Barbiturate 1,000,000 BAR 1,400 Nembutal Pentobarbital Barbiturate 100,000 BAR 300 Alphenal Phenallylmal Barbiturate 100,000 BAR 100 Luminal Phenobarbital Barbiturate 100,000 BAR 150 Luminal metabolite Phenobarbital metab.(Hydroxyphenobarbital, p-) Barbiturate 100,000 BAR 350 Seconal Secobarbital Barbiturate 100,000 BAR 300 Lotusate Talbutal Barbiturate 100,000 BAR 200 Surital Thiamylal Anesthetic 100,000 BAR 40,000

Sources: 1. Merck Index 2. Disposition of Toxic Drugs Chemicals in Man 3. Physicians Desk Reference 2000 Rev.A 10-8-2002 TOX Specificity-Drug Class Biosite Inc. Page 58

BENZODIAZEPINES

Highest Conc. Tested Conc. Giving Positive TRADE NAME CHEMICAL NAME DRUG CLASS (ng/ml) (ng/ml) Deracyn Adinazolam Benzodiazepine 100,000 BZO 1,000 Deracyn metabolite Adinazolam, Desmethyl Benzodiazepine metabolite 100,000 BZO 250 Xanax Alprazolam Benzodiazepine 100,000 BZO 100 Xanax metabolite Alprazolam, 4-Hydroxy- Benzodiazepine metabolite 100,000 BZO 250 Xanax metabolite Alprazolam-glucuronide, a-Hydroxy Benzodiazepine metabolite 5,000 BZO 150 Xanax metabolite Alprazolam, a-Hydroxy- Benzodiazepine metabolite 100,000 BZO 50 Durazanil Bromazepam Benzodiazepine 100,000 BZO 750 Durazanil metabolite Bromazepam,Hydroxylated cleavage product Benzodiazepine metabolite 100,000 BZO 50,000 Librium Chlordiazepoxide Benzodiazepine 100,000 BZO 13,000 Librium metabolite Chlordiazepoxide-desmethyl Chlordiazepoxide metabolite 100,000 BZO 9,000 Frisium Clobazam Benzodiazepine 100,000 BZO 2,000 Klonopin Clonazepam Benzodiazepine 100,000 BZO 250 Klonopin metabolite Clonazepam metab.(7-AminoClonazepam) Benzodiazepine metabolite 100,000 BZO 15,000 Tranxene Clorazepate Benzodiazepine 100,000 BZO 1,600 Delorazepam Delorazepam Benzodiazepine 100,000 BZO 600 Demoxepam Demoxepam Benzodiazepine 100,000 BZO 7,700 Valium Diazepam Benzodiazepine 100,000 BZO 200 ProSom Estazolam Benzodiazepine 100,000 BZO 300 Rohypnol Flunitrazepam Benzodiazepine 100,000 BZO 150 Rohypnol metabolite Flunitrazepam metab.(7-Aminoflunitrazepam) Benzodiazepine 100,000 BZO 7,500 Dalmane Flurazepam Benzodiazepine 100,000 BZO 100 Dalmane metabolite Flurazepam metab.(Desalkylflurazepam) Benzodiazepine 100,000 BZO 200 Dalmane metabolite Flurazepam metab.(N-Hydroxyethyl Flurazepam) Flurazepam metabolite 100,000 BZO 50 Paxipam Halazepam Benzodiazepine 100,000 BZO 100 Ativan Lorazepam Benzodiazepine 100,000 BZO 200 Ativan metabolite Lorazepam glucuronide Benzodiazepine metabolite 10,000 BZO 300 Ergocalm Lormetazepam Benzodiazepine 100,000 BZO 250 Nobrium Medazepam Benzodiazepine 100,000 BZO 32,000 Versed Midazolam Benzodiazepine 100,000 BZO 300 Versed metabolite Midazolam metab.(a-Hydroxymidazolam) Benzodiazepine metabolite 10,000 BZO 200 Mogadon Nitrazepam Benzodiazepine 100,000 BZO 2,600 Nordaz Nordiazepam Benzodiazepine 100,000 BZO 700

Sources: 1. Merck Index 2. Disposition of Toxic Drugs Chemicals in Man 3. Physicians Desk Reference 2000 Rev.A 10-8-2002 TOX Specificity-Drug Class Biosite Inc. Page 59

BENZODIAZEPINES

Highest Conc. Tested Conc. Giving Positive TRADE NAME CHEMICAL NAME DRUG CLASS (ng/ml) (ng/ml) Serax Oxazepam Benzodiazepine 100,000 BZO 3,500 Serax metabolite Oxazepam glucuronide Benzodiazepine metabolite 10,000 BZO 1,100 Centrax Prazepam Benzodiazepine 100,000 BZO 1,400 Centrax metabolite Prazepam metab.(3-HydroxyPrazepam) Benzodiazepine metabolite 100,000 BZO 250 Dormalin/Prosedar metabolite Quazepam metab.(2-Oxo-Quazepam) Benzodiazepine metabolite 100,000 BZO 100 Restoril Temazepam Benzodiazepine 100,000 BZO 200 Restoril metabolite Temazepam glucuronide Benzodiazepine metabolite 10,000 BZO 1,000 Halcion Triazolam Benzodiazepine 100,000 BZO 50 Halcion metabolite Triazolam, 4-OH- Benzodiazepine metabolite 100,000 BZO 100 Halcion metabolite Triazolam, a-OH- Benzodiazepine metabolite 100,000 BZO 100

COCAINE

Highest Conc. Tested Conc. Giving Positive TRADE NAME CHEMICAL NAME DRUG CLASS (ng/ml) (ng/ml) Cocaine Cocaine Anesthetic 100,000 COC 100,000 Cocaine byproduct Cocaine byproduct(Ecgonine) Anesthetic 100,000 COC 133,000 Cocaine metabolite Cocaine metab.(Benzoylecgonine) Cocaine metabolite 100,000 COC 300 Cocaine metabolite Cocaine metab.(Benzoylnorecgonine) Benzoylecgonine metab. 100,000 COC 100,000

Sources: 1. Merck Index 2. Disposition of Toxic Drugs Chemicals in Man 3. Physicians Desk Reference 2000 Rev.A 10-8-2002 TOX Specificity-Drug Class Biosite Inc. Page 60

OPIATES

Highest Conc. Tested Conc. Giving Positive TRADE NAME CHEMICAL NAME DRUG CLASS (ng/ml) (ng/ml) Donnatal metabolite Atropine metab.(Tropine) Atropine metabolite 2,000,000 OPI 2,000,000 Codeine Codeine Narcotic analgesic 100,000 OPI 300 Codeine metabolite Codeine metab.(Norcodeine) Codeine metabolite 300,000 OPI 300,000 Romilar Dextromethorphan Antitussive/Opiate 5,000,000 OPI 5,000,000 Heroin Diacetylmorphine Narcotic 100,000 OPI 300 Heroin byproduct Diacetylmorphine byproduct(Acetylcodeine, 6-) Opiate 100,000 OPI 250 Heroin metabolite Diacetylmorphine metab.(Acetylmorphine, 6- /6-MAM ) Narcotic Opiate 100,000 OPI 300 Synalgos Dihydrocodeine Narcotic analgesic 300,000 OPI 250 Dionin Ethylmorphine Antitussive/Opiate 100,000 OPI 300 Vicodin Hydrocodone Antitussive/Narcotic analgesic 100,000 OPI 1,700 Dilaudid Hydromorphone Narcotic analgesic 100,000 OPI 1,700 Levaquin Levofloxacin Antibiotic 2,500,000 OPI 2,500,000 Levo-Dromoran Levorphanol (Dextrorphan, l-) Narcotic analgesic 100,000 OPI 25,000 Morphine/Roxicet Morphine Narcotic analgesic 100,000 OPI 300 Morphine metabolite Morphine 3-ß-glucuronide Morphine metabolite 100,000 OPI 450 Morphine metabolite Morphine metab.(Normorphine) Narcotic analgesic 300,000 OPI 200,000 Lethidrone Nalorphine Narcotic antagonist 300,000 OPI 1,900 Narcan Naloxone Narcotic antagonist 300,000 OPI 200,000 Codeine metabolite Norcodeine Codeine metabolite 300,000 OPI 300,000 Percodan/Oxycontin Oxycodone Narcotic analgesic 100,000 OPI 23,000 Numorphan Oxymorphone Narcotic analgesic 100,000 OPI 41,000 Tuxi Pholcodine Antitussive/Opiate 100,000 OPI 400 Paramorphine Thebaine Opiate 100,000 OPI 24,000

Sources: 1. Merck Index 2. Disposition of Toxic Drugs Chemicals in Man 3. Physicians Desk Reference 2000 Rev.A 10-8-2002 TOX Specificity-Drug Class Biosite Inc. Page 61

PHENCYCLIDINE/PCP

Highest Conc. Tested Conc. Giving Positive TRADE NAME CHEMICAL NAME DRUG CLASS (ng/ml) (ng/ml) PCP analog PCE (n-Ethyl-1-Phenylcyclohexylamine) PCP analog 100,000 PCP 5,000 PCP/Angel dust PCP/Phencyclidine PCP 100,000 PCP 25 PCP metabolite PCP metab.(Hydroxy PCP, 4-) PCP metabolite 100,000 PCP 25,000 PCP analog PCPy (1-(1-Phenylcyclohexyl)-pyrrolidine) PCP analog 100,000 PCP 400 PCP analog TCM (1-[1-(2-Thienyl)cyclohexyl]-morpholine) PCP analog 100,000 PCP 10,000 PCP analog TCPy (1-[1-(2-Thienyl)cyclohexyl]-pyrrolidine) PCP analog 100,000 PCP 250

Sources: 1. Merck Index 2. Disposition of Toxic Drugs Chemicals in Man 3. Physicians Desk Reference 2000 Rev.A 10-8-2002 TOX Specificity-Drug Class Biosite Inc. Page 62

TETRAHYDROCANNABINOIDS/THC

Highest Conc. Tested Conc. Giving Positive TRADE NAME CHEMICAL NAME DRUG CLASS (ng/ml) (ng/ml) Histazol Astemizole Antihistamine 100,000 THC 20,000 Tegretol Carbamazepine Anticonvulsant 100,000 THC 10,000 Tegretol metabolite Carbamazepine, 10,11-Dihydroxy- Carbamazepine metabolite 100,000 THC 60,000 Chlorodiazepam, 4- Chlorodiazepam, 4- Benzodiazepine 100,000 THC 20,000 Propulsid Cisapride Peristaltic stimulant 100,000 THC 60,000 Clozaril metabolite Clozapine metab.(Desmethylclozapine) Clozapine metabolite 100,000 THC 40,000 Avlosulfon Dapsone Antibacterial 100,000 THC 40,000 Nupercaine Dibucaine Anesthetic 1,000,000 THC 100,000 Lodine Etodolac Anti-inflammatory 100,000 THC 50,000 Wytensin Guanabenz Antihypertensive 100,000 THC 20,000 Lomir Isradipine Antianginal 100,000 THC 90,000 Nicotine Nicotine Vasoconstrictor 1,000,000 THC 200,000 Protonix Pantoprazole Anti-ulcerative 1,000,000 THC 750,000 Paxil Paroxetine Antidepressant 100,000 THC 20,000 Dibenzyline Phenoxybenzamine Antihypertensive 100,000 THC 25,000 Neantine Phthalic acid Organic solvent 100,000 THC 25,000 Enteramine Serotonin (5-hydroxytryptamine) Neurotransmitter 100,000 THC 20,000 Zocor Simvastatin Antihyperlipidemic 100,000 THC 60,000 THC THC(Cannabinol) Cannabinoid 100,000 THC 20,000 THC THC(Cannabinol, D8-) Cannabinoid 200,000 THC 5,000 THC/Marinol THC(Cannabinol, D9-) Cannabinoid 1,000,000 THC 40,000 THC THC, 11-nor-9-carboxy-D8- Cannabinoid 100,000 THC 4,000 THC THC, l-11-Hydroxy-D9- Cannabinoid 10,000 THC 10,000 THC THC, l-11-nor-9-carboxy-D9- Cannabinoid 10,000 THC 50 THC THC, l-11-nor-9-carboxy-D9-glucuronide Cannabinoid metabolite 1,000 THC 50 Zearalenone Zearalenone Anabolic 100,000 THC 60,000

Sources: 1. Merck Index 2. Disposition of Toxic Drugs Chemicals in Man 3. Physicians Desk Reference 2000 Rev.A 10-8-2002 TOX Specificity-Drug Class Biosite Inc. Page 63

TRICYCLIC /TCA

Highest Conc. Tested Conc. Giving Positive TRADE NAME CHEMICAL NAME DRUG CLASS (ng/ml) (ng/ml) Elavil Amitriptyline Tricyclic antidepressant 100,000 TCA 750 Elavil metabolite Amitriptyline metabolite(d,l-E-10-Hydroxy-Amitriptyline) Amitriptyline metabolite 100,000 TCA 250 Anafranil Clomipramine Tricyclic antidepressant 100,000 TCA 12,500 Anafranil metabolite Clomipramine metab.(Norclomipramine) Clomipramine metabolite 100,000 TCA 75,000 Flexeril Cyclobenzaprine Muscle relaxant 100,000 TCA 1,900 Norpramine Desipramine Tricyclic antidepressant 100,000 TCA 1,000 Prothiaden Dothiepin Tricyclic Antidepressant 100,000 TCA 1,000 Sinequan Doxepin Tricyclic antidepressant 100,000 TCA 1,300 Sinequan metabolite Doxepin metab.(Nordoxepin) Doxepin metabolite 100,000 TCA 1,500 Tofranil Imipramine Tricyclic antidepressant 100,000 TCA 600 Pamelor/Aventyl Nortriptyline Tricyclic antidepressant 100,000 TCA 1,100 Pamelor/Aventyl metabolite Nortriptyline metabolite (+/- E-10-hydroxylated) Nortriptyline metabolite 100,000 TCA 750 Pamelor/Aventyl metabolite Nortriptyline metabolite (+/- Z-10-hydroxylated) Nortriptyline metabolite 100,000 TCA 5,000 Vivactil Protriptyline Tricyclic antidepressant 100,000 TCA 3,300 Surmontil Trimipramine Tricyclic antidepressant 100,000 TCA 3,000

Sources: 1. Merck Index 2. Disposition of Toxic Drugs Chemicals in Man 3. Physicians Desk Reference 2000