Ovid: A Comparison of the Effects of Hypothermia, Pentobarbital, and...ne on Cerebral Energy Stores at the Time of Ischemic Depolarization.
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A Comparison of the Effects of Hypothermia, Pentobarbital, and Isoflurane on Cerebral Energy Stores at the Time of Ischemic Depolarization
Author(s): Verhaegen, Marleen MD; Iaizzo, Paul A. PhD; Todd, Michael M. MD ISSN: 0003- Issue: Volume 82(5), May 1995, pp 1209-1215 3022 Publication Type: [Laboratory Investigation] Accession: Publisher: © 1995 American Society of Anesthesiologists, Inc. 00000542- (Verhaegen) Associate Professor, Department of Anesthesia, Universitaire Zickenhuizen 199505000- Leuven, Leuven, Belgium. 00016 (Iaizzo) Assistant Professor, Department of Anesthesiology and Department of Physiology, Email University of Minnesota School of Medicine, Minneapolis, Minnesota. Jumpstart (Todd) Professor and Vice Chair, Department of Anesthesia, University of Iowa College of Find Medicine. Institution(s): Citing Received from the Neuroanesthesia Research Laboratory, Department of Anesthesia. Articles University of Iowa College of Medicine, Iowa City, Iowa. Submitted for publication November ≪ 1, 1994. Accepted for publication January 6, 1995. Table Address reprint requests to Dr. Todd: Department of Anesthesia, University of Iowa College of of Medicine, 200 Hawkins Drive, Iowa City, Iowa 52242-1079. Address electronic mail to: Contents [email protected]. About
Table of Contents: this ≪ The Relation between Cerebral Metabolic Rate and Ischemic Depolarization: A Comparison of the Journal Effects of Hypothermia, Pentobarbital, and Isoflurane. ≫ ≫ Nitric Oxide Modulation of Pulmonary Blood Flow Distribution in Lobar Hypoxia.
Abstract Links Background: In an accompanying article, we report that hypothermia (27-28 Abstract degrees Celsius) delayed postischemic cortical depolarization longer than did Complete Reference large-dose pentobarbital or isoflurane anesthesia, even though preischemic ExternalResolverBasic cerebral metabolic rates for glucose were similar in the three groups. To examine Outline the mechanism that may underlie these differences, we measured the cerebral concentrations of high-energy phosphates (including adenosine triphosphate [ATP] and adenosine diphosphate) in normal conditions and at
● Abstract the moment of depolarization.
● Materials and Methods