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Nasal Rinse and Gargling As an Effort in Preventing COVID-19 Infection with Islamic Approach

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Nasal Rinse and Gargling As an Effort in Preventing COVID-19 Infection with Islamic Approach REVIEW Bali Medical Journal (Bali MedJ) 2021, Volume 10, Number 2: 503-506 P-ISSN.2089-1180, E-ISSN: 2302-2914 Nasal rinse and gargling as an effort in preventing COVID-19 infection with Islamic approach- Published by Bali Medical Journal a literature review Budi Yanti1*, Imam Maulana2, Debby Sofiana2, Liesa Sufani2, Noraliyatun Jannah3 ABSTRACT 1Department of Pulmonology and Medical Respirology, School of Medicine, Due to the COVID-19 pandemic, the general public must comply with health protocols and adopt new habits as this disease Universitas Syiah Kuala, Banda Aceh; spreads through droplets and enters the respiratory tract through the nose and mouth. Meanwhile, water penetration into 2Faculty of Medicine, Universitas Syiah the nasal cavity (istinsyaq) and out (istintsar) during ablution corresponds to the nasal rinse and gargling methods, which Kuala, Banda Aceh; prevents the mechanical and chemical attachment of viruses. This article discusses the role of Islamic-based nasal rinse and 3Basic Science and Fundamental of gargling in the prevention of COVID-19 infection. Nursing Department, Faculty of Nursing, Various solutions such as plain water, saline, povidone-iodine, and antiseptics have chemical effects. Gargling and nasal rinse Universitas Syiah Kuala, Banda Aceh; mechanically and chemically wash the mucosal surface in the mouth and nose to prevent the attachment of virus and other pathogens. Mechanically, the difference in concentration causes water to move outside the cell by osmosis, reducing mucus *Corresponding author: secretion and releasing the virus. Meanwhile, a chemical mechanism occurs when the free iodine in povidone-iodine oxidizes Budi Yanti; fatty acids and damages the virus cell walls and the respiratory chain of cytosolic enzymes, hence preventing inflammation Department of Pulmonology and of the host cell. However, the choice of liquid type, concentration, duration, and frequency of use still need to be considered Medical Respirology, School of Medicine, to prevent side effects. Universitas Syiah Kuala, Banda Aceh; [email protected] Keywords: COVID-19, Gargling, Islamic, Nasal Rinse. Cite This Article: Yanti, B., Maulana, I., Sofiana, D., Sufani, L., Jannah, N. 2021. Nasal rinse and gargling as an effort in Received: 2021-04-18 preventing COVID-19 infection with Islamic approach-a literature review. Bali Medical Journal 10(2): 503-506. DOI: 10.15562/ Accepted: 2021-06-19 bmj.v10i2.2397 Published: 2021-06-26 INTRODUCTION istintsar is the opposite.5 The breathing Nasal Rinse and Gargling as The of water into the nasal cavity (istinsyaq) Prevention of COVID-19 Novel coronavirus (COVID-19), also and out (istintsar) during ablution as A nasal rinse is a simple technique known as severe acute respiratory Islamic approach corresponds with the to clean out the nasal passages with a syndrome coronavirus 2 (SARS-CoV-2), concept of the nasal rinse and gargling solution gently. Meanwhile, oral rinse or is a new public health crisis threatening methods, which prevent the mechanical gargling is an effort to clean the oral cavity the world with increasing prevalence.1 and chemical attachment of viruses. There through water disposal.8,9 Chemically, To Date, more than 110 million cases are several types of holy water suitable for nasal rinse and gargling have antiviral have been confirmed, with over 2 million ablution, including rain, spring, sea, river effects that induce damage to the virus mortality cases.1,2 The body parts with and well water, and dew and snow.5 cell wall, thereby preventing inflammation the highest viral load include nasal cavity, Although study regarding the effect and disintegration of the respiratory nasopharynx and oropharynx, lymphocyte of istinsyaq and istintsar for reducing cytosolic enzymes chain. Mechanically, an of oral tissues, goblets and ciliated cells the number of pathogens is still limited, osmosis effect which is a process of water within the respiratory epithelium of the various studies have proven that practicing movement from hypotonic to hypertonic nose. These parts have the highest main nasal rinse and gargling using plain concentration is induced, resulting in a receptor for SARS-CoV-2, i.e., ACE2 water or hypertonic saline can reduce reduction in mucus secretion, and the (angiotensin converting enzyme II) the number of pathogens, including viral pathogen flushing with the water stream. receptor.3,4 The COVID-19 pandemic load.6,7 Besides, nasal rinse and gargling Nasal rinses interrupt the viscous surface requires the public to comply with health with pure water also tend to incite layer, mucus separating and its related protocols and adopt new habits as this mechanical resistance to viruses, resulting particulate matter. Also, the presence of disease spreads through droplets and in increased mucus secretion.7,8 Therefore, nasal saline improves the deeper aqueous enters the respiratory tract through the this study aims to examine the role of layer hydration, thereby increasing the nose and mouth.1 Islamic-based gargling and nasal rinse in underlying strength of the ciliary beat Istinsyaq refers to the process of preventing COVID-19 infection. and decreasing local inflammatory breathing water into the nostrils, while mediators.6,8–10 PublishedOpen access: by Baliwww.balimedicaljournal.org Medical Journal | Bali Medical Journal 2021; 10(2): 503-506 | doi: 10.15562/bmj.v10i2.2397 503 REVIEW During a viral respiratory infection, airway-lining fluid properties, increasing and nasal rinse.24 This practice was where mucociliary dysfunction and the lung exhalation capability, resulting in recommended for health workers and mucostasis occur secondary to the the expulsion of foreign particles from the patients with suspected and confirmed inflammatory response, the chemical airway.6,15 De Servi B et al. noted that the COVID-19 cases to reduce cross-infection and mechanical action of nasal rinse properties of isotonic saline are very close in the hospital setting. However, gargling and gargling is especially helpful. Hence, to the natural human plasma; therefore, using 0.4% povidone-iodine tends to these actions are an effective method it is effective in reducing the number of inactivate the ACE2 oropharyngeal of eliminating antigens, inflammatory pathogens and harmless to the respiratory receptor and salivary glands against SARS- mediators, decreasing viral load, which mucosa.16 CoV-2.3,25 act as an alternative non-pharmacological Hypertonic saline with a concentration Besides, nasal rinse or oral gargling preventive method to reduce transmission of > 0.9% has a higher osmolarity. Hence, using Povidone-iodine has proven to be rates.6,8 it can draw water from inside the cell relatively safe as it causes no discoloration and leads to increased hydration of the of the tongue or teeth and incites no Types of Solution mucosal layer that boosts the mucociliary changes in taste sensation.9 However, a. Plain Water clearance activity of the nose and usage > 2.5% is not recommended as it Flushing of the nasal cavity using plain provides mechanical protection against incites toxic effects on the nasal mucosa water facilitates mucus as well as debris the COVID-19 virus.6 When repeatedly and ciliated epithelium.21 evacuation. Several studies showed that practiced, nasal rinsing and gargling using by performing ablution like saline as nasal hypertonic saline increases Cl-ions that d. Other antiseptics rinse gold standard with plain water once, fight preliminary SARS-CoV-2 infection The use of chlorhexidine has previously there was a ½ reduction in pathogens and had a positive impact on reducing the been observed in viruses having an number, suggesting that when it is done COVID-19 virus.17 Several studies showed envelope composed of fat such as five times like the practice of ablution in that individuals who practice nasal rinse herpes virus, influenza A, hepatitis B. Islamic ritual, it is possible to achieve a and gargling using hypertonic saline had a However, 0.12% chlorhexidine had minimum pathogen number in the nasal shorter duration of illness and were the best no significant effect on COVID-19 cavity.7,11 choice in inhibiting viral replication.10,18 patients. Nevertheless, SARS-CoV-2 was The plain water used in ablution tends Therefore, saline is recommended because reportedly suppressed after 15 mL 0.12% to reduce microbial contamination.12 the procedure is simple and cheap. Also, chlorhexidine application.9 Besides, due to the size of SARS-CoV-2 the use of saline as a nasal rinse or oral Hydrogen peroxide is often used in (about 125 nm), it is thoughtful to install gargling rarely causes side effects.8 tooth procedures, and a previous study a water filter having a 10 nm or 1 nm pore reported that 3% H2O2 was effective size; this enables the mechanical clearance c. Povidone Iodine against adenovirus, rhinovirus and of the SARS-CoV-2 virus from the nasal Povidone-iodine is a useful virucidal agent coronavirus 229E strain, as these viruses cavity. Furthermore, boiling water before that induces oxidation of the viral nuclear were inactivated for 1-30 minutes by using it for nasal rinse or gargling is also structure, thereby destroying the viral oxidizing the viral envelope resulting in important to ensure water cleanliness.12,13 capsid and envelope.19 When dissolved in a decline in salivary viral load.9 Besides, water, it produces free iodine compounds 0.5% H2O2 also inactivated viruses such b. Saline that oxidize fatty acids in the viral cell as MERS-CoV, SARS-CoV, and HCoV The use of seawater-based saline as a nasal walls and inhibit inflammation of the after 1-minute application.26 rinse three times a day for eight weeks host tissue, leading to the inactivation of Ethanol has distinctive virucidal tends to alleviate symptoms of respiratory the SARS-CoV-2 virus.3 A study in Japan activity, where the use of 62-71% ethanol tract infections and sufficient in reducing also supported the virucidal activity was effective in inactivating viruses.
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