SR-B1 Uptake of HDL Promotes Prostate Cancer Proliferation and Tumor Progression
bioRxiv preprint doi: https://doi.org/10.1101/2020.02.24.963454; this version posted February 26, 2020. The copyright holder for this preprint (which was not certified by peer review) is the author/funder, who has granted bioRxiv a license to display the preprint in perpetuity. It is made available under aCC-BY-ND 4.0 International license. HDL uptake by SR-B1 drives prostate cancer proilferation SR-B1 uptake of HDL promotes prostate cancer proliferation and tumor progression C. Alicia Traughber1,2, Emmanuel Opoku1, Gregory Brubaker1, Jennifer Major1#, Hanxu Lu1, Shuhui Wang Lorkowski1, Chase Neumann1,2, Aimalie Hardaway3, Yoon-Mi Chung3, Kailash Gulshan1, Nima Sharifi3, J. Mark Brown1,2,4,5, and Jonathan D. Smith1,2* 1Department of Cardiovascular and Metabolic Sciences, Cleveland Clinic Lerner Research Institute, Cleveland, Ohio, 44195, USA; 2Department of Molecular Medicine, Cleveland Clinic Lerner College of Medicine of Case Western Reserve University, Cleveland, Ohio, 44195, USA; 3Department of Cancer Biology, Cleveland Clinic Lerner Research Institute, Cleveland, OH 44195, USA; 4Comprehensive Cancer Center, Case Western Reserve University, Cleveland, Ohio, 44106, USA; 5Center for Microbiome and Human Health, Cleveland Clinic Foundation, Cleveland, Ohio, 44195, USA Running title: HDL uptake by SR-B1 drives prostate cancer proliferation #Present address: Department of Molecular Biology and Microbiology, School of Medicine, Case Western Reserve University,10900 Euclid Ave, Cleveland, OH, 44106-4960, USA *To whom correspondence should
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