2015 Sego Lily Newsletter
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Clinical Uses and Toxicity of Ephedra Sinica: an Evidence-Based Comprehensive Retrospective Review (2004–2017)
Pharmacogn J. 2019; 11(1): 447-452 A Multifaceted Journal in the field of Natural Products and Pharmacognosy Review Article www.phcogj.com | www.journalonweb.com/pj | www.phcog.net Clinical uses and Toxicity of Ephedra sinica: An Evidence-Based Comprehensive Retrospective Review (2004–2017) Walaa Al saeed1, Marwa Al Dhamen1, Rizwan Ahmad2*, Niyaz Ahmad3, Atta Abbas Naqvi4 ABSTRACT Background: Ephedra sinica (ES) (Ma-huang) is a well-known plant due to its widespread therapeutic uses. However, many adverse effects such as hepatitis, nephritises, and cardio- vascular toxicity have been reported for this plant. Few of these side effects are reversible whereas others are irreversible and may even lead to death. Aim of the Study: The aim of this study was to investigate the clinical uses and toxicity cases/consequences associated 1 Walaa Al saeed , Marwa Al with the use of ES. The review will compare and evaluate the cases reported for ES and identify Dhamen1, Rizwan Ah- the causes which make the plant a poisonous one. Materials and Methods: An extensive mad2*, Niyaz Ahmad3, Atta literature review was conducted from 2004 to 2017, and research literature regarding the Abbas Naqvi4 clinical cases were collected using databases and books such as Google Scholar, Science Direct, Research gate, PubMed, and Web of Science/Thomson Reuters whereas the keywords 1College of Clinical Pharmacy, Imam searched were “Ephedra sinica,” clinical cases of Ephedra sinica, “Ma-hung poisonous,” Abdulrahman Bin Faisal University, “Ma-hung toxicity reported cases and treatment,” and “Ephedra Sinica toxicity reported cases Dammam, SAUDI ARABIA. and treatment.” Results: eleven different cases were identified which met the eligibility criteria 2Natural Products and Alternative Medi- and were studied in detail to extract out the findings. -
Chemical Analysis of Mountain Sheep Forage in the Virgin Mountains, Arizona
Chemical Analysis of Mountain Sheep Forage in the Virgin Mountains, Arizona Item Type text; Book Authors Morgart, John R.; Krausman, Paul R.; Brown, William H.; Whiting, Frank M. Publisher College of Agriculture, University of Arizona (Tucson, AZ) Rights Copyright © Arizona Board of Regents. The University of Arizona. Download date 01/10/2021 12:00:30 Link to Item http://hdl.handle.net/10150/310778 Chemical Analysis of Mountain Sheep Forage in the Virgin Mountains, Arizona John R. Morgart and Paul R. Krausman School of Renewable Natural Resources William H. Brown and Frank M. Whiting Department of Animal Sciences University of Arizona College of Agriculture Technical Bulletin 257 July 1986 Chemical Analysis of Mountain Sheep Forage in the Virgin Mountains, Arizona By John R. Morgart and Paul R. Krausman School of Renewable Natural Resources, University of of Arizona and William H. Brown and Frank M. Whiting Department of Animal Sciences, University of Arizona Abstract. Eighteen forage species used by mountain sheep (Ovis cana- densis) were collected monthly in 1981 and analyzed for dry matter, pro- tein, acid detergent fiber, neutral detergent fiber, lignin, ether extract, ash, calcium, phosphorus, carotene, and combustible energy. Baseline data on plant nutrition are presented in tabular form as a reference source for wildlife biologists, range managers, and scientists in related fields. Introduction Mountain sheep diets have been studied in Texas (Hailey 1968), New Mexico (Howard and DeLorenzo 1975), Arizona (Halloran and Crandell 1953, Seegmiller and Ohmart 1982), California (Dunaway 1970, Ginnett and Douglas 1982), Nevada (Barrett 1964, Deming 1964, Yoakum 1966, Brown et al. 1976, Brown et al. -
Discrimination of Three Ephedra Species and Their Geographical
www.nature.com/scientificreports OPEN Discrimination of three Ephedra species and their geographical origins based on multi-element Received: 6 December 2017 Accepted: 22 June 2018 fngerprinting by inductively Published: xx xx xxxx coupled plasma mass spectrometry Xiaofang Ma1, Lingling Fan1, Fuying Mao1,2, Yunsheng Zhao1,2,3, Yonggang Yan4, Hongling Tian5, Rui Xu1, Yanqun Peng1 & Hong Sui1,2 Discrimination of species and geographical origins of traditional Chinese medicine (TCM) is essential to prevent adulteration and inferior problems. We studied Ephedra sinica Stapf, Ephedra intermedia Schrenk et C.A.Mey. and Ephedra przewalskii Bge. to investigate the relationship between inorganic element content and these three species and their geographical origins. 38 elemental fngerprints from six major Ephedra-producing regions, namely, Inner Mongolia, Ningxia, Gansu, Shanxi, Shaanxi, and Sinkiang, were determined to evaluate the importance of inorganic elements to three species and their geographical origins. The contents of 15 elements, namely, N, P, K, S, Ca, Mg, Fe, Mn, Na, Cl, Sr, Cu, Zn, B, and Mo, of Ephedra samples were measured using inductively coupled plasma mass spectroscopy. Elemental contents were used as chemical indicators to classify species and origins of Ephedra samples using a radar plot and multivariate data analysis, including hierarchical cluster analysis (HCA), principal component analysis (PCA), and discriminant analysis (DA). Ephedra samples from diferent species and geographical origins could be diferentiated. This study showed that inorganic elemental fngerprint combined with multivariate statistical analysis is a promising tool for distinguishing three Ephedra species and their geographical origins, and this strategy might be an efective method for authenticity discrimination of TCM. -
Scientific Assessment of Ephedra Species (Ephedra Spp.)
Annex 3 Ref. Ares(2010)892815 – 02/12/2010 Recognising risks – Protecting Health Federal Institute for Risk Assessment Annex 2 to 5-3539-02-5591315 Scientific assessment of Ephedra species (Ephedra spp.) Purpose of assessment The Federal Office of Consumer Protection and Food Safety (BVL), in collaboration with the ALS working party on dietary foods, nutrition and classification issues, has compiled a hit list of 10 substances, the consumption of which may pose a health risk. These plants, which include Ephedra species (Ephedra L.) and preparations made from them, contain substances with a strong pharmacological and/or psychoactive effect. The Federal Ministry of Food, Agriculture and Consumer Protection has already asked the EU Commission to start the procedure under Article 8 of Regulation (EC) No 1925/2006 for these plants and preparations, for the purpose of including them in one of the three lists in Annex III. The assessment applies to ephedra alkaloid-containing ephedra haulm. The risk assessment of the plants was carried out on the basis of the Guidance on Safety Assessment of botanicals and botanical preparations intended for use as ingredients in food supplements published by the EFSA1 and the BfR guidelines on health assessments2. Result We know that ingestion of ephedra alkaloid-containing Ephedra haulm represents a risk from medicinal use in the USA and from the fact that it has now been banned as a food supplement in the USA. Serious unwanted and sometimes life-threatening side effects are associated with the ingestion of food supplements containing ephedra alkaloids. Due to the risks described, we would recommend that ephedra alkaloid-containing Ephedra haulm be classified in List A of Annex III to Regulation (EC) No 1925/2006. -
Gymnosperms the MESOZOIC: ERA of GYMNOSPERM DOMINANCE
Chapter 24 Gymnosperms THE MESOZOIC: ERA OF GYMNOSPERM DOMINANCE THE VASCULAR SYSTEM OF GYMNOSPERMS CYCADS GINKGO CONIFERS Pinaceae Include the Pines, Firs, and Spruces Cupressaceae Include the Junipers, Cypresses, and Redwoods Taxaceae Include the Yews, but Plum Yews Belong to Cephalotaxaceae Podocarpaceae and Araucariaceae Are Largely Southern Hemisphere Conifers THE LIFE CYCLE OF PINUS, A REPRESENTATIVE GYMNOSPERM Pollen and Ovules Are Produced in Different Kinds of Structures Pollination Replaces the Need for Free Water Fertilization Leads to Seed Formation GNETOPHYTES GYMNOSPERMS: SEEDS, POLLEN, AND WOOD THE ECOLOGICAL AND ECONOMIC IMPORTANCE OF GYMNOSPERMS The Origin of Seeds, Pollen, and Wood Seeds and Pollen Are Key Reproductive SUMMARY Innovations for Life on Land Seed Plants Have Distinctive Vegetative PLANTS, PEOPLE, AND THE Features ENVIRONMENT: The California Coast Relationships among Gymnosperms Redwood Forest 1 KEY CONCEPTS 1. The evolution of seeds, pollen, and wood freed plants from the need for water during reproduction, allowed for more effective dispersal of sperm, increased parental investment in the next generation and allowed for greater size and strength. 2. Seed plants originated in the Devonian period from a group called the progymnosperms, which possessed wood and heterospory, but reproduced by releasing spores. Currently, five lineages of seed plants survive--the flowering plants plus four groups of gymnosperms: cycads, Ginkgo, conifers, and gnetophytes. Conifers are the best known and most economically important group, including pines, firs, spruces, hemlocks, redwoods, cedars, cypress, yews, and several Southern Hemisphere genera. 3. The pine life cycle is heterosporous. Pollen strobili are small and seasonal. Each sporophyll has two microsporangia, in which microspores are formed and divide into immature male gametophytes while still retained in the microsporangia. -
Chromosome Numbers in Gymnosperms - an Update
Rastogi and Ohri . Silvae Genetica (2020) 69, 13 - 19 13 Chromosome Numbers in Gymnosperms - An Update Shubhi Rastogi and Deepak Ohri Amity Institute of Biotechnology, Research Cell, Amity University Uttar Pradesh, Lucknow Campus, Malhaur (Near Railway Station), P.O. Chinhat, Luc know-226028 (U.P.) * Corresponding author: Deepak Ohri, E mail: [email protected], [email protected] Abstract still some controversy with regard to a monophyletic or para- phyletic origin of the gymnosperms (Hill 2005). Recently they The present report is based on a cytological data base on 614 have been classified into four subclasses Cycadidae, Ginkgoi- (56.0 %) of the total 1104 recognized species and 82 (90.0 %) of dae, Gnetidae and Pinidae under the class Equisetopsida the 88 recognized genera of gymnosperms. Family Cycada- (Chase and Reveal 2009) comprising 12 families and 83 genera ceae and many genera of Zamiaceae show intrageneric unifor- (Christenhusz et al. 2011) and 88 genera with 1104 recognized mity of somatic numbers, the genus Zamia is represented by a species according to the Plant List (www.theplantlist.org). The range of number from 2n=16-28. Ginkgo, Welwitschia and Gen- validity of accepted name of each taxa and the total number of tum show 2n=24, 2n=42, and 2n=44 respectively. Ephedra species in each genus has been checked from the Plant List shows a range of polyploidy from 2x-8x based on n=7. The (www.theplantlist.org). The chromosome numbers of 688 taxa family Pinaceae as a whole shows 2n=24except for Pseudolarix arranged according to the recent classification (Christenhusz and Pseudotsuga with 2n=44 and 2n=26 respectively. -
Pharmacognostical and Phytochemical Investigation of Sida
International Journal of Pharmacy and Pharmaceutical Sciences Academic Sciences ISSN- 0975-1491 Vol 4, Issue 1, 2012 Research Article PHARMACOGNOSTIC AND PHYTOCHEMICAL INVESTIGATION OF SIDA CORDIFOLIA L.-A THREATENED MEDICINAL HERB PRAMOD V. PATTAR.* AND M. JAYARAJ. P. G. Department of Botany, Karnatak University, Dharwad, Karnataka, India. Email: [email protected] Received: 12 Feb 2011, Revised and Accepted: 18 May 2011 ABSTRACT Sida cordifolia L. is threatened medicinal herb, belongs to the family Malvaceae. The plant is used in traditional system of medicine for healing various diseases. However, the present study was aimed to evaluate the parameters to determine the quality of the plant. This study comprises of morphological, microscopical and preliminary phytochemical investigations of the herb. Keywords: Malvaceae, Pharmacognosy, Phytochemical screening, Sida cordifolia L. INTRODUCTION Drying of plant material Sida cordifolia L. is commonly known as “Indian Ephedra”, Bala The whole plant material of Sida cordifolia L. was subjected to shade (Sanskrit), Hetthuti-gida (Kannada) and Country Mallow (English) is drying for about 10 weeks. The shade dried plant material was further an important medicinal herb belongs to the family Malvaceae. The crushed to powder and the powder was passed through the mesh 22 whole plant of Sida cordifolia is used as medicinal herb, because leaves and stored in air tight container for further analysis. contain small quantities of both ephedrine and pseudoephidrine1, roots and seeds contain alkaloid ephedrine, vasicinol, vasicinone, and Macroscopic and microscopic analysis 2,3,4 N-methyl tryptophan and is extensively used as a common herbal The macroscopic and microscopic examinations of plant studied were 5, 6 drug . -
US Fish and Wildlife Service
BARNEBY REED-MUSTARD (S. barnebyi ) CLAY REED-MUSTARD SHRUBBY REED-MUSTARD (S,arguillacea) (S. suffrutescens) .-~ U.S. Fish and Wildlife Service UTAH REED—MUSTARDS: CLAY REED-MUSTARD (SCHOENOCRAMBE ARGILLACEA) BARNEBY REED—MUSTARD (SCHOENOCRAMBE BARNEBYI) SI-IRUBBY REED-MUSTARD (SCHOENOCRAMBE SUFFRUTESCENS) RECOVERY PLAN Prepared by Region 6, U.S. Fish and Wildlife Service Approved: Date: (~19~- Recovery plans delineate reasonable actions which are believed to be required to recover and/or protect the species. Plans are prepared by the U.S. Fish and Wildlife Service, sometimes with the assistance of recovery teams, contractors, State agencies, and others. Objectives will only be attained and funds expended contingent upon appropriations, priorities, and other budgetary constraints. Recovery plans do not necessarily represent the views or the official positions or approvals of any individuals or agencies, other than the U.S. Fish and Wildlife Service, involved in the plan formulation. They represent the official position of the U.S. Fish and Wildlife Service only after they have been signed by the Regional Director or Director as an~roved Approved recovery plans are subject to modification as dictated by new findings, changes in species status, and the completion of recovery tasks. Literature Citation should read as follows: U.S. Fish and Wildlife Service. 1994. Utah reed—mustards: clay reed—mustard (Schoenocrambe argillacea), Barneby reed-mustard (Schoenocrambe barnebyl), shrubby reed—mustard (Schoenacranibe suffrutescens) recovery plan. Denver, Colorado. 22 pp. Additional copies may be purchased from: Fish and Wildlife Reference Service 5430 Grosvenor Lane, Suite 110 Bethesda, Maryland 20814 Telephone: 301/492—6403 or 1—800—582—3421 The fee for the plan varies depending on the number of pages of the plan. -
Vegetation Classification and Map Accuracy Assessment of the Proposed Tehachapi Pass High-Speed Rail Corridor Vegetation Map
Vegetation Classification and Map Accuracy Assessment of the Proposed Tehachapi Pass High-Speed Rail Corridor Vegetation Map Kern County, California Prepared for the Strategic Growth Council by the California Department of Fish and Wildlife Vegetation Classification and Mapping Program September 2015 ABSTRACT The Geographical Information Center (GIC) at California State University, Chico, completed a vegetation map of the Proposed Tehachapi Pass High-Speed Rail Corridor (HSRC), covering 199,493 acres. The project was funded by the Strategic Growth Council to support routing and mitigation planning for the high-speed rail system. The map was produced using heads-up digitizing based on 2012 National Agricultural Imagery Program (NAIP) imagery. The minimum mapping unit (MMU) is one acre for most vegetation types, with a smaller MMU for wetlands. Although the primary purpose of the map is to document vegetation communities, it provides additional structural data such as herbaceous, shrub, and tree cover, and information about the level of disturbance within the vegetation stand. This report describes the tasks performed by the California Department of Fish and Wildlife Vegetation Classification and Mapping Program (VegCAMP), specifically, the creation of a vegetation classification for the project area and the accuracy assessment of the map. The overall accuracy of the map exceeded the state standard of 80%. ii ACKNOWLEDGMENTS Funding for this project was provided by the Strategic Growth Council, California Wildlife Conservation Board and -
Sequence Analysis of Chloroplast Chlb Gene of Medicinal Ephedra Species and Its Application to Authentication of Ephedra Herb
June 2006 Biol. Pharm. Bull. 29(6) 1207—1211 (2006) 1207 Sequence Analysis of Chloroplast chlB Gene of Medicinal Ephedra Species and Its Application to Authentication of Ephedra Herb a a b b b Yahong GUO, Ayako TSURUGA, Shigeharu YAMAGUCHI, Koji OBA, Kasumi IWAI, c,1) ,a Setsuko SEKITA and Hajime MIZUKAMI* a Graduate School of Pharmaceutical Sciences, Nagoya City University; 3–1 Tanabe-dori, Mizuho-ku, Nagoya 467–8603, Japan: b Research and Development Department, Asgen Pharmaceutical Co., Ltd.; 2–28–8 Izumi, Higashi-ku, Nagoya 461–8531, Japan: and c Tsukuba Medicinal Plant Research Station, National Institute of Health Sciences; 1 Hachimandai, Tsukuba, Ibaraki 305–0843, Japan. Received December 26, 2005; accepted February 15, 2006 Chloroplast chlB gene encoding subunit B of light-independent protochlorophyllide reductase was amplified from herbarium and crude drug specimens of Ephedra sinica, E. intermedia, E. equisetina, and E. przewalskii. Se- quence comparison of the chlB gene indicated that all the E. sinica specimens have the same sequence type (Type S) distinctive from other species, while there are two sequence types (Type E1 and Type E2) in E. equisetina. E. intermedia and E. prezewalskii revealed an identical sequence type (Type IP). E. sinica was also identified by di- gesting the chlB fragment with Bcl I. A novel method for DNA authentication of Ephedra Herb based on the se- quences of the chloroplast chlB gene and internal transcribed spacer of nuclear rRNA genes was developed and successfully applied for identification of the crude drugs obtained in the Chinese market. Key words chloroplast chlB; DNA authentication; Ephedra Herb; polymerase chain reaction-restriction fragment length poly- morphism Ephedra Herb is an important crude drug which has been nucleotide deletions were present in the trnL/trnF spacer of used in Chinese and Japanese traditional (Kampo) medi- E. -
Threatened, Endangered, Candidate & Proposed Plant Species of Utah
TECHNICAL NOTE USDA - Natural Resources Conservation Service Boise, Idaho and Salt Lake City, Utah TN PLANT MATERIALS NO. 52 MARCH 2011 THREATENED, ENDANGERED, CANDIDATE & PROPOSED PLANT SPECIES OF UTAH Derek Tilley, Agronomist, NRCS, Aberdeen, Idaho Loren St. John, PMC Team Leader, NRCS, Aberdeen, Idaho Dan Ogle, Plant Materials Specialist, NRCS, Boise, Idaho Casey Burns, State Biologist, NRCS, Salt Lake City, Utah Last Chance Townsendia (Townsendia aprica). Photo by Megan Robinson. This technical note identifies the current threatened, endangered, candidate and proposed plant species listed by the U.S.D.I. Fish and Wildlife Service (USDI FWS) in Utah. Review your county list of threatened and endangered species and the Utah Division of Wildlife Resources Conservation Data Center (CDC) GIS T&E database to see if any of these species have been identified in your area of work. Additional information on these listed species can be found on the USDI FWS web site under “endangered species”. Consideration of these species during the planning process and determination of potential impacts related to scheduled work will help in the conservation of these rare plants. Contact your Plant Material Specialist, Plant Materials Center, State Biologist and Area Biologist for additional guidance on identification of these plants and NRCS responsibilities related to the Endangered Species Act. 2 Table of Contents Map of Utah Threatened, Endangered and Candidate Plant Species 4 Threatened & Endangered Species Profiles Arctomecon humilis Dwarf Bear-poppy ARHU3 6 Asclepias welshii Welsh’s Milkweed ASWE3 8 Astragalus ampullarioides Shivwits Milkvetch ASAM14 10 Astragalus desereticus Deseret Milkvetch ASDE2 12 Astragalus holmgreniorum Holmgren Milkvetch ASHO5 14 Astragalus limnocharis var. -
Responses of Plant Communities to Grazing in the Southwestern United States Department of Agriculture United States Forest Service
Responses of Plant Communities to Grazing in the Southwestern United States Department of Agriculture United States Forest Service Rocky Mountain Research Station Daniel G. Milchunas General Technical Report RMRS-GTR-169 April 2006 Milchunas, Daniel G. 2006. Responses of plant communities to grazing in the southwestern United States. Gen. Tech. Rep. RMRS-GTR-169. Fort Collins, CO: U.S. Department of Agriculture, Forest Service, Rocky Mountain Research Station. 126 p. Abstract Grazing by wild and domestic mammals can have small to large effects on plant communities, depend- ing on characteristics of the particular community and of the type and intensity of grazing. The broad objective of this report was to extensively review literature on the effects of grazing on 25 plant commu- nities of the southwestern U.S. in terms of plant species composition, aboveground primary productiv- ity, and root and soil attributes. Livestock grazing management and grazing systems are assessed, as are effects of small and large native mammals and feral species, when data are available. Emphasis is placed on the evolutionary history of grazing and productivity of the particular communities as deter- minants of response. After reviewing available studies for each community type, we compare changes in species composition with grazing among community types. Comparisons are also made between southwestern communities with a relatively short history of grazing and communities of the adjacent Great Plains with a long evolutionary history of grazing. Evidence for grazing as a factor in shifts from grasslands to shrublands is considered. An appendix outlines a new community classification system, which is followed in describing grazing impacts in prior sections.