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Figure 1
A
M7 M10M4 M2 M12 M11 M3 M1/ M8 M6 M9 M5 B CD Mesenchymal Basal
M1 M5 M8
M11 M9 M10
M6 M3 EF M7 Classical Atypical
M12
M4 M2
G ME1 ME2 ME3 ME4 ME5
ME6 ME7 ME8 ME9 ME10 ME11
ME12
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Figure 2
A
T-cell signature corDeviance
r = 0.61, p < 2.2 x 10-16
Module membership: regulation of immune system process (kME8) B
r = -0.86, p < 2.2 x 10-16 corDeviance
Myeloid signature
Module membership: leukocyte activation (kME1)
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ABC
M4
M3
M6
M1
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M10 DE
NES = -5.37, FDR > 0.001
| | 1.0 -1.0 k_cME6 Hypoxia signature eigengene signature Hypoxia
Leukocyte activation (meta_cME6)
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Upregulated glucose metabolism correlates inversely with CD8+ T cell infiltration and survival in squamous cell carcinoma
Christian H Ottensmeier, Kate L Perry, Elena L Harden, et al.
Cancer Res Published OnlineFirst May 20, 2016.
Updated version Access the most recent version of this article at: doi:10.1158/0008-5472.CAN-15-3121
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