Late-Breaking Supplement
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2017 Annual Meeting Abstract Supplement LATE-BREAKING ABSTRACT SUBMISSIONS These abstracts are available via the Mobile Event App, Online Planner, and a downloadable PDF from the SOT website. All Late-Breaking Abstracts are presented on Thursday, March 16, from 8:30 am–11:45 am. www.toxicology.org THURSDAY POSTER SESSION MAP March 16, 2017—8:30 AM to 11:45 AM—Hall A Poster Set Up—7:30 AM to 8:30 AM Late-Breaking Poster #s: P196-P540 (highlighted in gray) P540 P539 P538 P537 P533 P534 P535 P536 P532 P531 P530 P529 P528 P527 P526 P525 P524 P523 P522 P521 P520 P519 P518 P517 P516 P515 P497 P498 P499 P500 P501 P502 P503 P504 P505 P506 P507 P508 P509 P510 P511 P512 P513 P514 P496 P495 P494 P493 P492 P491 P490 P489 P488 P487 P486 P485 P484 P483 P482 P481 P480 P479 P461 P462 P463 P464 P465 P466 P467 P468 P469 P470 P471 P472 P473 P474 P475 P476 P477 P478 P460 P459 P458 P457 P456 P455 P454 P453 P452 P451 P450 P449 P448 P447 P446 P445 P444 P443 P425 P426 P427 P428 P429 P430 P431 P432 P433 P434 P435 P436 P437 P438 P439 P440 P441 P442 P424 P423 P422 P421 P420 P419 P418 P417 P416 P415 P414 P413 P412 P411 P410 P409 P408 P407 P389 P390 P391 P392 P393 P394 P395 P396 P397 P398 P399 P400 P401 P402 P403 P404 P405 P406 P388 P387 P386 P385 P384 P383 P382 P381 P380 P379 P378 P377 P376 P375 P374 P373 P372 P371 P353 P354 P355 P356 P357 P358 P359 P360 P361 P362 P363 P364 P365 P366 P367 P368 P369 P370 P352 P351 P350 P349 P348 P347 P346 P345 P344 P343 P342 P341 P340 P339 P338 P337 P336 P335 P317 P318 P319 P320 P321 P322 P323 P324 P325 P326 P327 P328 P329 P330 P331 P332 P333 P334 P316 P315 P314 P313 P312 P311 P310 P309 P308 P307 P306 P305 P304 P303 P302 P301 P300 P299 P281 P282 P283 P284 P285 P286 P287 P288 P289 P290 P291 P292 P293 P294 P295 P296 P297 P298 P280 P279 P278 P277 P276 P275 P274 P273 P272 P271 P270 P269 P268 P267 P266 P265 P264 P263 P245 P246 P247 P248 P249 P250 P251 P252 P253 P254 P255 P256 P257 P258 P259 P260 P261 P262 P244 P243 P242 P241 P240 P239 P238 P237 P236 P235 P234 P233 P232 P231 P230 P229 P228 P227 P209 P210 P211 P212 P213 P214 P215 P216 P217 P218 P219 P220 P221 P222 P223 P224 P225 P226 P208 P207 P206 P205 P204 P203 P202 P201 P200 P199 P198 P197 P196 P195 P194 P193 P192 P191 P173 P174 P175 P176 P177 P178 P179 P180 P181 P182 P183 P184 P185 P186 P187 P188 P189 P190 P172 P171 P170 P169 P168 P167 P166 P165 P164 P163 P162 P161 P160 P159 P158 P157 P156 P155 P137 P138 P139 P140 P141 P142 P143 P144 P145 P146 P147 P148 P149 P150 P151 P152 P153 P154 P136 P135 P134 P133 P132 P131 P130 P129 P128 P127 P126 P125 P124 P123 P122 P121 P120 P119 P101 P102 P103 P104 P105 P106 P107 P108 P109 P110 P111 P112 P113 P114 P115 P116 P117 P118 Entrance Photography and video in all poster sessions is prohibited without the consent of the poster presenter(s)/author(s). Please respect your colleagues' rights to privacy. Thursday, March 16, Late-Breaking Poster Session by Location Session Title Abstract #s Poster Board #s Late-Breaking Poster Session 1 Author Attended: 8:30 AM-10:00 AM Emerging Technologies 3227-3230 P196-P199 Biological Modeling 3231-3235 P200-P204 Epidemiology and Public Health 3236-3240 P205-P209 Exposure Assessment/Biomonitoring 3241-3249 P210-P218 Regulation/Policy; Risk Assessment 3250-3267 P219-P236 Safety Assessment: Non-Pharm./Drug Development/Drug Discovery 3268-3288 P237-P257 Immunotoxicity; Inflammation 3289-3298 P258-P267 Late-Breaking Poster Session 2 Author Attended: 10:00 AM-11:45 AM Food Safety/Nutrition; Natural Products 3299-3315 P269-P285 Air Pollution Toxicology 3316-3322 P286-P292 Respiratory Toxicology 3323-3334 P293-P304 Persistent Organic Pollutants (POPs) 3335-3341 P305-P311 Cardiovascular Toxicology/Hemodynamics 3342-3348 P312-P318 Carcinogenesis and Oxidative Injury/Redox Biology 3349-3355 P319-P325 Late-Breaking Poster Session 3 Author Attended: 8:30 AM-10:00 AM Biomarkers 3356-3361 P327-P332 Cell Death/Apoptosis; Autoimmunity/Hypersensitivity; Bioinformatics 3362-3365 P333-P336 Animal Models 3366-3369 P337-P340 Alternatives to Mammalian Models 3370-3377 P341-P348 Chemical and Biological Weapons; Ecotoxicology 3378-3389 P349-P360 Computational Toxicology and Data Integration 3390-3398 P361-P369 Late-Breaking Poster Session 4 Author Attended: 10:00 AM-11:45 AM Clinical and Translational Toxicology 3399-3401 P371-P373 Developmental/Juvenile Toxicology; Reproductive Toxicology 3402-3421 P374-P393 Endocrine Toxicology 3422-3430 P394-P402 Epigenetics 3431-3433 P403-P405 Medical Devices 3434-3437 P406-P409 Education, Ethical, Legal, and Social Issues; Systems Biology and Toxicology 3438-3444 P410-P416 Late-Breaking Poster Session 5 Author Attended: 8:30 AM-10:00 AM Metals 3445-3458 P418-P431 Neurotoxicity: Metals, Pesticides 3459-3467 P432-P440 Neurodegenerative Disease 3468-3472 P441-P445 Neurotoxicity: Developmental, General 3473-3487 P446-P460 Ocular Toxicology; Pesticides 3488-3497 P461-P470 Stem Cell Biology and Toxicology 3498-3503 P471-P476 Late-Breaking Poster Session 6 Author Attended: 10:00 AM-11:45 AM Disposition/Pharmacokinetics 3504-3508 P479-P483 Gene Regulation/Signal Transduction; Genotoxicity/DNA Repair 3509-3521 P484-P496 Kidney; Liver; Skin 3522-3535 P497-P510 Mixtures 3536-3539 P511-P514 Nanotoxicology 3540-3546 P515-P521 Pharmacogenomics/Genetic Polymorphisms; Receptors 3547-3549 P522-P524 General Toxicology 3550-3563 P525-P538 i TOPIC ABSTRACT #s POSTER BOARD #s Session Title Late-Breaking Poster Air Pollution Toxicology 3316-3322 P286-P292 Session 2 Late-Breaking Poster Alternatives to Mammalian Models 3370-3377 P341-P348 Session 3 Late-Breaking Poster Animal Models 3366-3369 P337-P340 Session 3 Late-Breaking Poster Autoimmunity/Hypersensitivity 3364 P335 Session 3 Late-Breaking Poster Bioinformatics 3365 P336 Session 3 Late-Breaking Poster Biological Modeling 3231-3235 P200-P204 Session 1 Late-Breaking Poster Biomarkers 3356-3361 P327-P332 Session 3 Late-Breaking Poster Carcinogenesis 3349-3355 P319-P325 Session 2 Late-Breaking Poster Cardiovascular Toxicology/Hemodynamics 3342-3348 P312-P318 Session 2 Late-Breaking Poster Cell Death/Apoptosis 3362-3363 P333-P334 Session 3 Late-Breaking Poster Chemical and Biological Weapons 3378-3386 P349-P357 Session 3 Late-Breaking Poster Clinical and Translational Toxicology 3399-3401 P371-P373 Session 4 Computational Toxicology and Data Late-Breaking Poster Integration 3390-3398 P361-P369 Session 3 Late-Breaking Poster Developmental and Juvenile Toxicology 3402-3412 P374-P384 Session 4 Late-Breaking Poster Disposition/Pharmacokinetics 3504-3508 P479-P483 Session 6 Late-Breaking Poster Ecotoxicology 3387-3389 P358-P360 Session 3 Late-Breaking Poster Education, Ethical, Legal, and Social Issues 3438-3439 P410-P411 Session 4 Late-Breaking Poster Emerging Technologies 3227-3230 P196-P199 Session 1 Late-Breaking Poster Endocrine Toxicology 3422-3430 P394-P402 Session 4 Late-Breaking Poster Epidemiology and Public Health 3236-3240 P205-P209 Session 1 Late-Breaking Poster Epigenetics 3431-3433 P403-P405 Session 4 Late-Breaking Poster Exposure Assessment/Biomonitoring 3241-3249 P210-P218 Session 1 ii TOPIC ABSTRACT #s POSTER BOARD #s Session Title Late-Breaking Poster Gene Regulation/Signal Transduction 3509-3510 P484-P485 Session 6 Late-Breaking Poster General Toxicology 3550-3563 P525-P538 Session 6 Late-Breaking Poster Genotoxicity/DNA Repair 3511-3521 P486-P496 Session 6 Late-Breaking Poster Inflammation 3297-3298 P266-P267 Session 1 Late-Breaking Poster Immunotoxicity 3289-3296 P258-P265 Session 1 Late-Breaking Poster Kidney 3522-3525 P497-P500 Session 6 Late-Breaking Poster Liver 3526-3533 P501-P508 Session 6 Late-Breaking Poster Medical Devices 3434-3437 P406-P409 Session 4 Late-Breaking Poster Metals 3445-3458 P418-P431 Session 5 Late-Breaking Poster Mixtures 3536-3539 P511-P514 Session 6 Late-Breaking Poster Nanotoxicology 3540-3546 P515-P521 Session 6 Late-Breaking Poster Natural Products 3312-3315 P282-P285 Session 2 Late-Breaking Poster Neurotoxicity/Neurodegenerative Disease 3459-3487 P432-P460 Session 5 Late-Breaking Poster Ocular Toxicology 3488-3489 P461-P462 Session 5 Late-Breaking Poster Oxidative Injury and Redox Biology 3354-3355 P324-P325 Session 2 Late-Breaking Poster Persistent Organic Pollutants (POPs) 3335-3341 P305-P311 Session 2 Late-Breaking Poster Pesticides 3490-3497 P463-P470 Session 5 Pharmacogenomics/Genetic Late-Breaking Poster Polymorphisms 3547-3548 P522-P523 Session 6 Late-Breaking Poster Receptors 3549 P524 Session 6 Late-Breaking Poster Regulation/Policy 3250-3253 P219-P222 Session 1 Late-Breaking Poster Reproductive Toxicology 3413-3421 P385-P393 Session 4 iii TOPIC ABSTRACT #s POSTER BOARD #s Session Title Late-Breaking Poster Respiratory Toxicology 3323-3334 P293-P304 Session 2 Late-Breaking Poster Risk Assessment 3254-3267 P223-P236 Session 1 Late-Breaking Poster Safety Assessment: Non-Pharmaceutical 3268-3271 P237-P240 Session 1 Safety Assessment: Pharmaceutical-Drug Late-Breaking Poster Development and Drug Discovery 3272-3288 P241-P257 Session 1 Late-Breaking Poster Skin 3534-3535 P509-P510 Session 6 Late-Breaking Poster Stem Cell Biology and Toxicology 3498-3503 P471-P476 Session 5 Late-Breaking Poster Systems Biology and Toxicology 3440-3444 P412-P416 Session 4 iv 2017 Society of Toxicology Annual Meeting Late-Breaking Abstracts ABSTRACT NUMBER : 3227 Poster Board Number : P196 TITLE : The GARD Platform for Potency Assessment of Skin Sensitizing Chemicals AUTHORS (FIRST INITIAL, LAST NAME) AND INSTITUTIONS : A. Forreryd 1, K. Zeller 1, T. Lindberg 1, R. Gradin 2, A. Chawade 1, M. Lindstedt 1. 1Lund University, Lund, Sweden; 2SenzaGen, Lund, Sweden. KEYWORDS : Immunotoxicity; Potency, Chemical Testing ABSTRACT : Allergic Contact Dermatitis (ACD) constitutes a major problem for 15-20% of the population and develops upon repeated exposure to skin sensitizing chemicals.