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PROGRAM AGENDA October 11-15, 2015 San Francisco, CA I The Moscone Center
TCTCONFERENCE.COM TCT - Agenda
Last updated October 15, 2015 at 8:27 pm
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Saturday, October 10, 2015
24th Annual Cardiovascular Nurse and Technologist Symposium, Part 1 – Registered Cardiovascular Invasive Specialists (RCIS) Review Course Accreditation: CNE
Saturday, October 10 12:00 PM - 6:00 PM Room: Moscone North, Lower Level, Room 135
Session I. Fundamental Knowledge 12:00 PM - 1:45 PM Moderator: Thomas H. Maloney Discussants: Elena Ladich, George W. Vetrovec
12:00 PM Introduction and Session Objectives Thomas H. Maloney
12:05 PM In-depth Coronary Angiography and Coronary Complication Review Matched With Interactive Cadaver Heart Dissection Elena Ladich, George W. Vetrovec
12:45 PM In-depth Cardiac Structure, Conduction System, and Hemodynamic Review of the Normal Heart Matched With Interactive Cadaver Heart Dissection Elena Ladich, Tim J. Lapp
1:30 PM Keynote Lecture: Transcatheter Treatment of All Four Heart Valves – We’re Closer Than You Think! Azeem Latib
Session II. The Aortic Valve: A Deep Dive 1:45 PM - 3:05 PM Moderator: Thomas H. Maloney Discussants: Rajesh M. Dave, Jeff Davis, Paul D. Mahoney, Darren Powell
1:45 PM Fundamental Knowledge: Aortic Valve Anatomy, Function, and Relational Pathology Darren Powell
2:05 PM Hemodynamics of Aortic Stenosis With Gorlin/HAKKI Calculations Using the Telestrator Jeff Davis 2:25 PM Interventionalist Perspective: How I Interpret the Hemodynamic, CT, and Echo Data in TAVR Clinical Decision Making Paul D. Mahoney
2:50 PM Live Insertion of a Transcatheter Aortic Valve With Interventionalist Rajesh M. Dave
Session III. The Mitral Valve: A Deep Dive 3:05 PM - 4:15 PM Moderator: Jeff Davis Discussants: Tim J. Lapp, Darren Powell, Michael J. Rinaldi
3:05 PM Fundamental Knowledge: Mitral Valve Anatomy, Function, and Relational Pathology Tim J. Lapp
3:25 PM Hemodynamics of Mitral Regurgitation and Regurgitant Fraction Calculations Using the Telestrator Darren Powell
3:45 PM Interventionalist Perspective: How I Interpret the Hemodynamic and Echo Data in MitraClip Clinical Decision Making Michael J. Rinaldi
4:00 PM Live Insertion of a MitraClip With the Interventionalist Michael J. Rinaldi
Session IV. The Left Atrium: A Deep Dive 4:15 PM - 5:00 PM Moderator: Jeff Davis Discussants: Asma Hussaini, Brij Maini, Binita Shah
4:15 PM Fundamental Knowledge: Left Atrium and Left Atrial Appendage Anatomy, Function, and Relational Pathology Asma Hussaini
4:30 PM Potential Complications When Accessing the Left Atrium and How to Hemodynamically Identify Them Binita Shah
4:45 PM Live Insertion of a Left Atrial Appendage Occlusion Device With the Interventionalist Brij Maini
Session V. Hands on Hearts Bioskills Session (Room 132) 5:00 PM - 6:00 PM Moderator: Thomas H. Maloney Marsha Holton, Brian L. Kaminsky, Elena Ladich, Tim J. Lapp Discussants: Jeff Davis, Robert Kutys, Michelle Olson, Darren Powell 5:00 PM Cadaver Hearts (Courtesy of CVPath) Marsha Holton, Thomas H. Maloney
24th Annual Cardiovascular Nurse and Technologist Symposium – Nurse-Tech Reception (Sponsored by Boston Scientific Corporation) Accreditation: CNE
Saturday, October 10 6:00 PM - 7:00 PM Room: Moscone North, Lower Level, Outside Room 135
CardioVascular Professionals (CVP) Course: 24th Annual Cardiovascular Nurse and Technologist Symposium – Nurse-Tech Reception (Sponsored by Boston Scientific Corporation) 6:00 PM - 7:00 PM
Sunday, October 11, 2015
Clinical Trial Design and Interpretation, Part 1 Accreditation: CME/CNE
Sunday, October 11 12:00 PM - 6:00 PM Room: Moscone West, 2nd Floor, Room 2002 - 2004
Session I. Integrating Clinical Research and Clinical Practice 12:00 PM - 1:10 PM Moderators: David A. Cox, Thomas D. Stuckey Discussants: Kate Dalton, Marian C. Hawkey, Timothy D. Henry, James B. Hermiller Jr, Ioanna Kosmidou, Roxana Mehran, Giora Weisz, Bernhard Witzenbichler
12:00 PM Welcome and Session Objectives Roxana Mehran
12:05 PM Building a Successful Clinical Research Enterprise at Your Hospital: The Tool Box Bernhard Witzenbichler
12:15 PM Essentials of Quality and Compliance in Research Kate Dalton
12:25 PM How to Become a Well-Respected and Successful Investigator: It's Quality, Not Quantity James B. Hermiller Jr
12:35 PM Obtaining Informed Consent in Difficult Scenarios Case 1: Patient Presenting With STEMI Timothy D. Henry
12:40 PM Obtaining Informed Consent in Difficult Scenarios Case 2: The Elderly Patient Referred for TAVR Marian C. Hawkey
12:45 PM Obtaining Informed Consent in Difficult Scenarios Case 3: The Patient With a Language Barrier Giora Weisz
12:50 PM Roundtable Discussion With Audience Q&A
Session II. Biostatistics for the Clinician: The Basics and More 1:10 PM - 2:55 PM Moderators: Stuart J. Pocock, Jan Tijssen Discussants: Usman Baber, Marco Barbanti, Somjot S. Brar, David J. Cohen, Sanjay Kaul, Melissa Nichols, Binita Shah, Julie A. Swain
1:10 PM Observational vs Randomized Trials: Strengths and Weaknesses (With Case Examples) John L. Petersen
1:20 PM Roundtable Discussion With Audience Q&A
1:25 PM Subgroup Analyses: How Useful or Harmful Are They? Darrel P. Francis
1:35 PM Roundtable Discussion With Audience Q&A
1:40 PM Propensity-Matched Analysis: Advantages and Pitfalls (TRANSLATE and PROMETHEUS) Usman Baber
1:50 PM Roundtable Discussion With Audience Q&A
1:55 PM Strategy Trials vs Device/Drug Comparisons: Important Considerations David J. Cohen
2:05 PM Roundtable Discussion With Audience Q&A
2:10 PM Composite Endpoints/Primary Endpoints/Weighted Endpoints/Patient-Reported Endpoints: How to Choose the Right Endpoint Stuart J. Pocock
2:20 PM Roundtable Discussion With Audience Q&A
2:25 PM Meta-analysis (Standard and Network): The Good, the Bad, and the Ugly Somjot S. Brar
2:35 PM Roundtable Discussion With Audience Q&A
2:40 PM Bayesian Statistics: Can They Be Trusted (or Understood)?! Sanjay Kaul 2:50 PM Roundtable Discussion With Audience Q&A
Session III. Design and Rationale of Major Ongoing Trials: Critical Appraisal Prior to Results 2:55 PM - 5:00 PM Moderators: Ori Ben-Yehuda, Ajay J. Kirtane Discussants: Sripal Bangalore, Sanjay Kaul, Roxana Mehran, Shamir R. Mehta, Stuart J. Pocock, Patrick W. Serruys, A.J. Conrad C. Smith, Jennifer A. Tremmel
2:55 PM From COURAGE and BARI 2D to ISCHEMIA: What Answers Can We Expect (and Not Expect) From ISCHEMIA? Sripal Bangalore
3:10 PM Roundtable Discussion With Audience Q&A
3:20 PM From SYNTAX to EXCEL: What Answers Can We Expect (and Not Expect) From EXCEL? Patrick W. Serruys
3:35 PM Roundtable Discussion With Audience Q&A
3:45 PM From PRAMI, CvLPRIT, and Other Studies to COMPLETE: What Answers Can We Expect (and Not Expect) From COMPLETE? Shamir R. Mehta
4:00 PM Roundtable Discussion With Audience Q&A
4:10 PM From WOEST, DAPT, and PEGASUS to GLOBAL LEADERS and TWILIGHT: What Answers Can We Expect (and Not Expect) From GLOBAL LEADERS and TWILIGHT? Roxana Mehran
4:25 PM Roundtable Discussion With Audience Q&A
4:35 PM From SYMPLICITY HTN-3 to Ongoing Renal Denervation Studies: What Answers Can We Expect (and Not Expect) From the Ongoing RDN Studies? Ajay J. Kirtane
4:50 PM Roundtable Discussion With Audience Q&A
Session IV. Reporting and Analysis Issues: The Details 5:00 PM - 6:00 PM Moderators: Robert A. Harrington, Pascal Vranckx Discussants: Darrel P. Francis, Sanjay Kaul, John L. Petersen, Stuart J. Pocock, Jan Tijssen
5:00 PM How to Assess the Quality of Evidence From Peer-Reviewed Manuscripts: The Statistical Reviewer’s Vantage Point Jan Tijssen
5:15 PM Roundtable Discussion With Audience Q&A
5:20 PM When Is the Primary Endpoint Not Enough? Pitfalls in Primary Endpoint Selection and Assumptions, Power, and More Robert A. Harrington
5:35 PM Roundtable Discussion With Audience Q&A
5:40 PM The 10 Most Common Statistical Mistakes and Misinterpretations I See Again and Again Sanjay Kaul
5:55 PM Roundtable Discussion With Audience Q&A
The CTO Summit: Conquering the Final Frontier, Part 1 Accreditation: CME/CNE
Sunday, October 11 12:00 PM - 6:00 PM Room: Moscone West, 2nd Floor, Room 2020 - 2024
Session I. CTO PCI: Where Are We, and Where Are We Going? An Update on Registry Data 12:00 PM - 2:00 PM Moderators: J. Aaron Grantham, Masahiko Ochiai Discussants: Khaldoon Alaswad, Alfredo R. Galassi, Georgios Sianos, Julian Strange, Etsuo Tsuchikane, William M Wilson, Masahisa Yamane
12:00 PM Poll 1: What Percentage of Your CTO Attempts Use Only an Antegrade Approach? Poll Moderators: J. Aaron Grantham, Masahiko Ochiai
12:03 PM Poll 2: What Is Your Antegrade Success Rate? Poll Moderators: J. Aaron Grantham, Masahiko Ochiai
12:05 PM The Antegrade Approach: J-CTO Registry Insights Masahisa Yamane
12:15 PM The Antegrade Approach: Euro CTO Insights Alfredo R. Galassi
12:25 PM The Antegrade Approach: PROGRESS CTO Insights Emmanouil S. Brilakis
12:35 PM The Antegrade Approach: UK CTO Registry Insights Julian Strange
12:45 PM Roundtable Discussion With Audience Q&A
1:00 PM Poll 3: What Percentage of Your CTO Cases Do You Start With a Primary Retrograde Approach? Poll Moderators: J. Aaron Grantham, Masahiko Ochiai
1:03 PM Poll 4: What Percentage of Retrograde Collaterals Can You Cross With a Guidewire? Poll Moderators: J. Aaron Grantham, Masahiko Ochiai
1:05 PM The Retrograde Approach: J-CTO Registry Insights Etsuo Tsuchikane
1:15 PM The Retrograde Approach: Euro CTO Insights Georgios Sianos
1:25 PM The Retrograde Approach: PROGRESS CTO Insights Khaldoon Alaswad
1:35 PM The Retrograde Approach: UK CTO Registry Insights William M Wilson
1:45 PM Roundtable Discussion With Audience Q&A
Session II. CTO Program/Skills Development: Setting Up for Success at Your Institution 2:00 PM - 4:00 PM Moderators: Etsuo Tsuchikane, Gerald S. Werner Discussants: Christopher E. Buller, Joseph A Dens, Jonathan M. Hill, Sunao Nakamura, Masahiko Ochiai, James C. Spratt, Satoru Sumitsuji
2:00 PM Poll 5: How Many CTO PCIs per Year Does Your Center Currently Attempt? Poll Moderators: Etsuo Tsuchikane, Gerald S. Werner
2:03 PM Poll 6: What Percentage of Your Institution’s PCI Volume Should Be CTO PCI? Poll Moderators: Etsuo Tsuchikane, Gerald S. Werner
2:05 PM Why Do I Need A CTO PCI Program? Jeffrey W. Moses
2:15 PM What Has the Development of a CTO Program Meant to Our Institution? Jonathan M. Hill
2:25 PM What Are the Financial Barriers to Success? Local and Global Perspectives Scott Harding
2:35 PM What Are the Major Steps (and Hurdles) to Becoming a CTO Operator? James C. Spratt
2:45 PM Roundtable Discussion With Audience Q&A
2:55 PM Poll 7: How Many CTO PCIs Does It Take to Become a Master (ie, >90% Success With No Angiographic Exclusions)? Poll Moderators: Etsuo Tsuchikane, Gerald S. Werner
3:00 PM What You Need to Know About Histopathology/Anatomy to Be a Better CTO Operator Satoru Sumitsuji
3:10 PM What You Need to Know About Guidewires to Be a Better CTO Operator Christopher E. Buller 3:20 PM What You Need to Know About Microcatheters to Be a Better CTO Operator Masahiko Ochiai
3:30 PM What You Need to Know About Guides and Bilateral Access Joseph A Dens
3:40 PM Stents in CTO: If I Get It Open, Will It Stay Open? Sunao Nakamura
3:50 PM Roundtable Discussion With Audience Q&A
Session III. Let’s Debate Strategy/Concept 4:00 PM - 6:00 PM Moderators: Tony J. DeMartini, Dimitri Karmpaliotis, James M. McCabe Discussants: Yuji Hamazaki, Brian L. Kaminsky, Goran K. Olivecrona, Stéphane Rinfret, Bradley H. Strauss, Gerald S. Werner, R. Michael Wyman
4:00 PM Poll 8: Should Nearly All CTO PCIs Be Started Antegrade? Poll Moderators: Tony J. DeMartini, Dimitri Karmpaliotis
4:05 PM Position: You Should Always Start Antegrade! Bradley H. Strauss
4:15 PM Position: Who Cares How You Start; It Is All About How You Finish! R. Michael Wyman
4:25 PM Contemporary Reverse Cart and Its Impact on Retrograde CTO PCI Yuji Hamazaki
4:35 PM Guide Extension Reverse CART: The New Standard? Tony J. DeMartini
4:45 PM Roundtable Discussion With Audience Q&A
5:00 PM Poll 9: Are Subintimal Stents Worse Than True Lumen Stents? Poll Moderators: Tony J. DeMartini, Dimitri Karmpaliotis
5:05 PM Position: It’s All About the True Lumen! Gerald S. Werner
5:15 PM Inflow and Outflow Rules: If It’s in the Architecture, It’s Good! Stéphane Rinfret
5:25 PM Public Reporting of CTO PCI Failure Rates: Harmful or Stimulus to Appropriate Referral James M. McCabe
5:35 PM CTO PCI Failure Is Not an Option Goran K. Olivecrona 5:45 PM Roundtable Discussion With Audience Q&A
Left Atrial Appendage Closure: Indications, Technique, and Outcomes, Part 1 Accreditation: CME/CNE
Sunday, October 11 12:00 PM - 6:00 PM Room: Moscone West, 3rd Floor, Room 3002 - 3004
Session I. Background, Rationale, and Indications for LAA Closure 12:00 PM - 1:49 PM Moderators: David R. Holmes Jr., Vivek Y. Reddy Discussants: Michael Argenziano, Piera Capranzano, Anibal A. Damonte, Christopher B. Granger, Saibal Kar, DJ Lakkireddy, Pascal Vranckx, Uwe Zeymer
12:00 PM Weighing the Risk of Stroke in Atrial Fibrillation vs the Risk of Bleeding on Anticoagulation Neal S. Kleiman
12:12 PM Which NOAC for Which Patient? Christopher B. Granger
12:24 PM What Are the Management Options for the Patient With AF and DES? Pascal Vranckx
12:36 PM Outcome of Patients With Atrial Fibrillation and Stent Implantation: Results of the Prospective LASER Registry Uwe Zeymer
12:46 PM Surgical LAA Closure: Patient Selection and Supporting Data Michael Argenziano
12:58 PM Shades of Gray? Defining the Range of Patients Contraindicated for Anticoagulation Piera Capranzano
1:10 PM Guidelines, Recommendations, and Reimbursement for LAA Closure: A Global Survey Saibal Kar
1:22 PM Are Ablation and LAA Closure Complementary Approaches in the Patient With Paroxysmal AF With Moderate Stroke Risk? DJ Lakkireddy
1:34 PM Roundtable Discussion With Audience Q&A
Session II. Outcomes of LAA Closure 1:49 PM - 3:47 PM Moderators: Reda Ibrahim, Matthew J. Price Discussants: David R. Holmes Jr., Randall J. Lee, Jai-Wun Park, Elizabeth M Perpetua, Vivek Y. Reddy
1:49 PM Amplatzer Cardiac Plug (ACP): Updated Results and Future Directions Reda Ibrahim
2:04 PM Comprehensive Analysis of the Watchman Data: PROTECT AF, CAP, and PREVAIL David R. Holmes Jr.
2:19 PM Transpericardial LAA Closure: Results With the LARIAT and AMAZE Design and Rationale Randall J. Lee
2:34 PM Roundtable Discussion With Audience Q&A
2:44 PM Pre-debate Vote: Based on the Present Data, Is LAA Closure an Alternative to Oral Anticoagulation in Low Bleeding Risk Patients? Poll Moderators: Reda Ibrahim, Matthew J. Price
2:46 PM Debate: Is LAA Closure an Alternative to Oral Anticoagulation in Low Bleeding Risk Patients? No, It Should Be Limited to Anticoagulation Contraindicated Patients! Jai-Wun Park
2:54 PM Debate: Is LAA Closure an Alternative to Oral Anticoagulation in Low Bleeding Risk Patients? Yes, LAA Closure Is at Least as Good as Oral Anticoagulation! Saibal Kar
3:02 PM Post-debate Vote (Who Won?): Based on the Present Data, Is LAA Closure an Alternative to Oral Anticoagulation in Low Bleeding Risk Patients? Poll Moderators: Reda Ibrahim, Matthew J. Price
3:04 PM Roundtable Discussion With Audience Q&A
3:12 PM The Clinical Impact of Stroke With 2 Preventative Strategies: LAA Closure vs Chronic Oral Anticoagulation Vivek Y. Reddy
3:22 PM How to Establish a Successful LAA Occlusion Program
3:32 PM Roundtable Discussion With Audience Q&A
Session III. Technique of LAA Closure, Part 1 3:47 PM - 6:00 PM Moderators: Stefan C. Bertog, Josep Rodés-Cabau Discussants: Sergio Berti, William A. Gray, Randall J. Lee, Bushra S Rana, Vivek Y. Reddy
3:47 PM Pre-debate Vote: Should LAA Closure and AF Ablation Be Performed in the Same Setting? Poll Moderator: Josep Rodés-Cabau
3:49 PM Debate: Should LAA Closure and AF Ablation Be Performed in the Same Setting? Yes, It’s Safe and Cost-effective! Randall J. Lee
3:57 PM Debate: Should LAA Closure and AF Ablation Be Performed in the Same Setting? Of Course Not, They Should Be Staged Procedures! Vivek Y. Reddy
4:05 PM Post-debate Vote (Who Won?): Should LAA Closure and AF Ablation Be Performed in the Same Setting? Poll Moderator: Josep Rodés-Cabau
4:07 PM Roundtable Discussion With Audience Q&A
4:13 PM TEE Assessment Before, During, and After LAA Closure Bushra S Rana
4:28 PM CT Imaging Before, During, and After LAA Closure Sergio Berti
4:43 PM The Utility of ICE During LAA Closure Sergio Berti
4:55 PM Transseptal Puncture for LAA Closure: Therapy-Specific Considerations Stefan C. Bertog
5:10 PM Obtaining Pericardial Access for LAA Closure: Imaging and Tools William A. Gray
5:25 PM Edited Taped Case of LAA Closure: Step by step Case Presenter: Horst Sievert
5:40 PM Roundtable Discussion With Audience Q&A
Metallic Drug-Eluting Stents: Controversies With Today’s Technology Accreditation: CME/CNE
Sunday, October 11 12:00 PM - 6:00 PM Room: Moscone West, 3rd Floor, Room 3001 - 3005
Session I. Stent Platforms 12:00 PM - 1:45 PM Moderators: Stephen G. Ellis, John A. Ormiston Discussants: Giuseppe Biondi-Zoccai, Nicolas Foin, Lisette Okkels Jensen, Manel Sabate, Giulio G. Stefanini, Jochen Wöhrle
12:00 PM Design of Current-Generation Durable-Polymer Drug-Eluting Stents: More Alike or Different? John A. Ormiston 12:08 PM Clinical Outcomes of Current-Generation Durable-Polymer Drug-Eluting Stents: More Alike or Different? Sripal Bangalore
12:18 PM Pre-debate Vote: Bioabsorbable vs Durable Polymers – Is There a Difference in Efficacy, Safety, or Required DAPT Duration? Poll Moderators: Stephen G. Ellis, John A. Ormiston
12:20 PM Debate: Are Bioabsorbable Polymers Preferable to Durable Polymers for Efficacy, Safety, or Required DAPT Duration? Yes, Eliminating the Polymer to Leave Behind a Bare-Metal Stent Surface Is a Desirable and Clinically Meaningful Goal! Robert A. Byrne
12:27 PM Debate: Are Bioabsorbable Polymers Preferable to Durable Polymers for Efficacy, Safety, or Required DAPT Duration? No, This Theoretical Goal Does Not Hold Up Under Scrutiny! Tullio Palmerini
12:34 PM Roundtable Discussion With Audience Q&A
12:39 PM Post-debate Vote (Who Won?): Bioabsorbable vs Durable Polymers – Is There a Difference in Efficacy, Safety, or Required DAPT Duration? Poll Moderators: Stephen G. Ellis, John A. Ormiston
12:41 PM Durable-Polymer DES 5-Year Outcomes: XIENCE/PROMUS and PROMUS Element Update Gregg W. Stone
12:49 PM Durable-Polymer DES 5-Year Outcomes: RESOLUTE Update Sigmund Silber
12:57 PM Update on Biolimus-Eluting Stent Platforms: BioMatrix and Nobori Program Update Philip M. Urban
1:05 PM Everolimus-Eluting Bioabsorbable-Polymer DES Outcomes: SYNERGY Update Dean J. Kereiakes
1:13 PM What Have We Learned From “All-Comers” Head-to-Head DES Trials I? The SORT OUT Trial Evald H. Christiansen
1:23 PM What Have We Learned From “All-Comers” Head-to-Head DES Trials II? The COMPARE Trials Pieter C. Smits
1:30 PM Roundtable Discussion With Audience Q&A
Session II. Pharmacotherapy Controversies 1:45 PM - 3:18 PM Moderators: John A. Bittl, E. Magnus Ohman Discussants: Laurent Bonello, Giuseppe De Luca, Dmitriy N. Feldman, Fausto Feres, Hyeon-Cheol Gwon, Pascal Vranckx
1:45 PM Pre-debate Vote: What Is the Ideal Duration of DAPT After DES? Poll Moderators: John A. Bittl, E. Magnus Ohman
1:47 PM Debate: What Is the Ideal Duration of DAPT After DES? Longer Is Better (for Most)! David P. Lee
1:54 PM Debate: What Is the Ideal Duration of DAPT After DES? Shorter Is Best (for Most)! Hyeon-Cheol Gwon
2:01 PM Post-debate Vote (Who Won?): What Is the Ideal Duration of DAPT for Most DES Patients? Poll Moderators: John A. Bittl, E. Magnus Ohman
2:03 PM Lessons From the TAXUS Liberté/Prasugrel Substudy David P. Lee
2:10 PM Featured Lecture: New DAPT Duration Recommendations John A. Bittl
2:20 PM Featured Lecture: Should Stent Design Impact DAPT Duration Decisions? Insights From the DAPT Study James B. Hermiller Jr
2:30 PM Roundtable Discussion With Audience Q&A
2:42 PM Pre-debate Vote: Should Prasugrel and Ticagrelor Be Used in a Substantial Number of Patients With Stable CAD? Poll Moderators: John A. Bittl, E. Magnus Ohman
2:44 PM Debate: Should Prasugrel and Ticagrelor Be Used in a Substantial Number of Patients With Stable CAD? Yes, the Benefits Outweigh the Risks! Christoph A. Kaiser
2:51 PM Debate: Should Prasugrel and Ticagrelor Be Used in a Substantial Number of Patients With Stable CAD? No, the Risks Are Real and There Is No Evidence for Benefit! Jorge F. Saucedo
2:58 PM Roundtable Discussion With Audience Q&A
3:03 PM Post-debate Vote (Who Won?): Should Prasugrel and Ticagrelor Be Used in a Substantial Number of Patients With Stable CAD? Poll Moderators: John A. Bittl, E. Magnus Ohman
3:05 PM In Which Patients (if Any) Should BMS Be Used in 2015? Evidence and Common Sense Marco Valgimigli
3:13 PM Roundtable Discussion With Audience Q&A Session III. Revascularization Controversies 3:18 PM - 4:50 PM Moderators: Kevin J. Beatt, Craig R. Smith Discussants: David J. Cohen, Frederick Feit, Alfredo E. Rodriguez, Rod H. Stables, Alfredo Trento, David O. Williams
3:18 PM Critical Analysis of Current Guidelines on Multivessel Revascularization: Are They Up to Date? Marie-Claude Morice
3:26 PM The SYNTAX Score in Clinical Practice: Promise and Pitfalls Philippe Généreux
3:33 PM Are Risk Scores Practical and Useful to Differentiate PCI vs CABG? Davide Capodanno
3:40 PM Functional Risk Scoring: Fame 3 and Beyond William F. Fearon
3:47 PM Assessment and Implications of Surgical Inoperability: Who Is at High Risk? Robert W. Yeh
3:54 PM Roundtable Discussion With Audience Q&A
4:06 PM Case Presentation Pretreatment: MVD Disease With Intermediate SYNTAX Score: How Should This Patient Be Treated? Case Presenter: Javier Escaned
4:10 PM Discussion: How Should This Patient Be Treated?
4:16 PM How the Case Was Treated Case Presenter: Javier Escaned
4:18 PM Case Presentation: Pretreatment – A Patient With Class II Angina and Anterior Wall Ischemia Case Presenter: Hemal Gada
4:22 PM Pre-debate Vote: Should Most Patients With Stable Ischemic Heart Disease, Moderate or Greater Ischemia, and Controllable Symptoms Undergo Revascularization? Poll Moderators: Kevin J. Beatt, Craig R. Smith
4:24 PM Debate: Should Most Patients With Stable Ischemic Heart Disease, Moderate or Greater Ischemia, and Controllable Symptoms Undergo Revascularization? The Data Says Not as a First-Line Therapy! David J. Maron
4:32 PM Debate: Should Most Patients With Stable Ischemic Heart Disease, Moderate or Greater Ischemia, and Controllable Symptoms Undergo Revascularization? Yes, an Evidence-Based Position! Gregg W. Stone
4:40 PM Roundtable Discussion With Audience Q&A 4:46 PM Post-debate Vote (Who Won?): Should Most Patients With Stable Ischemic Heart Disease, Moderate or Greater Ischemia, and Controllable Symptoms Undergo Revascularization? Poll Moderators: Kevin J. Beatt, Craig R. Smith
4:48 PM How Was This Patient Treated? Case Presenter: Hemal Gada
Session IV. DES Thrombosis and Restenosis 4:50 PM - 6:00 PM Moderators: Robert A. Byrne, Stefan K. James Discussants: Fernando Alfonso, Edoardo Camenzind, Upendra Kaul, Dean J. Kereiakes, Takeshi Kimura, Paul S. Teirstein
4:50 PM Stent Thrombosis Update: Causes, Predictors, Implications, and Treatment Stefan K. James
5:02 PM New Insights Into Neoatherosclerosis as a Frequent “Common Denominator” of DES Failure Renu Virmani
5:09 PM Are There Differences in the Outcomes of Early, Late, and Very Late Stent Thrombosis? Donald Cutlip
5:16 PM Case Presentation Before Treatment: An Unexpected and Difficult to Treat Stent Thrombosis Case Presenter: Ehrin J. Armstrong
5:20 PM Discussion: Why Did Stent Thrombosis Occur, and How Should It Be Treated and Its Recurrence Prevented?
5:26 PM How Was the Case Treated Case Presenter: Ehrin J. Armstrong
5:28 PM Drug-Eluting Stent Restenosis State of the Art: Causes, Evaluation, and Treatment Fernando Alfonso
5:40 PM The Resurrection of “Historic” Therapies for Refractory Restenosis: Vascular Brachytherapy, Atherectomy, and Beyond Paul S. Teirstein
5:47 PM Case Presentation Before Second-Time Treatment: Recurrent DES Restenosis Case Presenter: Wojtek Wojakowski
5:51 PM Discussion: How Should This Case Be Evaluated and Treated?
5:58 PM How the Case Was Treated Case Presenter: Wojtek Wojakowski Optimizing Outcomes With Intravascular Imaging (IVUS, OCT, and NIRS): A Problem-Oriented Approach Accreditation: CME/CNE
Sunday, October 11 12:00 PM - 6:00 PM Room: Moscone West, 2nd Floor, Room 2001 - 2005
Session I. Preintervention Imaging 12:00 PM - 1:45 PM Moderators: Fernando Alfonso, Akiko Maehara Discussants: Itshac Itsik Ben-dor, Marco A. Costa, Robert T Gerber, Ryan D. Madder, Gary S. Mintz, Alan C. Yeung
12:00 PM IVUS and OCT Assessment of Left Main and Non–Left Main Lesion Severity: How and When Do They Correlate With Physiology? John McB. Hodgson
12:15 PM IVUS, OCT, and NIRS Identification of Culprit Lesions in ACS Jonathan M. Tobis
12:30 PM Culprit Lesions With Intact Fibrous Caps (Erosion): Recognition and the Case for Deferred Intervention Francesco Prati
12:40 PM Unusual Causes of Acute Coronary Syndrome: Spontaneous Dissections, Calcified Nodules, Takotsubo, Embolization, and More Fernando Alfonso
12:55 PM Predicting Periprocedure MI: Data From Grayscale and RF-IVUS, OCT, and NIRS Evelyn S. Regar
1:10 PM Prospective Identification of Non–Flow Limiting Vulnerable Plaques and Vulnerable Patients: Data From Grayscale and RF-IVUS, OCT, and NIRS for Predicting Future Events David Erlinge
1:25 PM Roundtable Discussion With Audience Q&A
Session II. Interventional Imaging Guidance 1:45 PM - 3:35 PM Moderators: Carlo Di Mario, John McB. Hodgson Discussants: Giulio Guagliumi, Seung-Jung Park, Enrico Romagnoli, Yasunori Ueda, Mladen I. Vidovich, Nick E. J. West
1:45 PM Guiding DES Implantation for LMCA (and Bifurcation) Lesions: Sizing, Avoiding Complications, Predictors of Events, and Evidence for Improved Outcomes Jose M. de la Torre Hernandez
2:00 PM Guiding DES Implantation for Non-LMCA Lesions: Sizing, Avoiding Complications, Predictors of Events, and Evidence for Improved Outcomes Giulio Guagliumi
2:15 PM Imaging to Guide BRS Implantation: Current Status, From Lesion Preparation to Device Sizing and Optimal Implantation Nick E. J. West
2:30 PM Treating CTO Lesions With Imaging Guidance Yasushi Asakura
2:45 PM Acute Complication Case Presentations 1: Dissections, Intramural Hematomas, and Perforations by IVUS (and Recommendations for Treatment) Akiko Maehara
2:55 PM Acute Complication Case Presentations 2: Dissections, Intramural Hematomas, and Perforations by OCT (and Recommendations for Treatment) Marc D. Feldman
3:05 PM Acute Complication Case Presentations 3: How Imaging (IVUS or OCT) Got Me Out of Trouble Evelyn S. Regar
3:15 PM Roundtable Discussion With Audience Q&A
Session III. Restenosis and Stent Thrombosis 3:35 PM - 4:50 PM Moderators: Soo-Jin Kang, Gary S. Mintz Discussants: Fernando Alfonso, Lisette Okkels Jensen, Yukio Ozaki, Enrico Romagnoli, Konstantinos Toutouzas
3:35 PM Polling Question: What Is/Are the Most Important Predictor(s) of In-Stent Restenosis or Stent Thrombosis? Moderators: Soo-Jin Kang, Gary S. Mintz
3:40 PM Mechanisms and Predictors and Treatment of In-Stent Restenosis Soo-Jin Kang
3:55 PM Mechanisms and Predictors of Early, Late, and Very Late Stent Thrombosis Lisette Okkels Jensen
4:10 PM Does Acute or Late Malapposition Cause Stent Thrombosis? Gary S. Mintz
4:20 PM Repeat Polling Question: What Is/Are the Most Important Predictor(s) of In-Stent Restenosis or Stent Thrombosis? Moderators: Soo-Jin Kang, Gary S. Mintz
4:25 PM Update on Neoatherosclerosis: Imaging Recognition, Prevalence, Predictors, and Prognosis Ziad A. Ali 4:35 PM Roundtable Discussion With Audience Q&A
Session IV. Special Topics 4:50 PM - 6:00 PM Moderators: Ziad A. Ali, Peter J. Fitzgerald Discussants: James A. Goldstein, Akiko Maehara, Francesco Prati, Jose M. de la Torre Hernandez
4:50 PM Practical Integration 1: A Modern Cath Lab–Based Imaging Service (and Lessons Learned) Ning Guo
5:00 PM Practical Integration 2: IVUS, RF-IVUS, OCT, and NIRS – How to Pick and Choose Gary S. Mintz
5:15 PM Assessment of Progression and Regression by IVUS, RF-IVUS, OCT, and NIRS: Changes of Plaque Volume vs Changes in Tissue Components and Lessons Learned Hector M. Garcia-Garcia
5:30 PM Future Directions: HD-IVUS, Micro-CT, Hybrid Catheters, and More Akiko Maehara
5:45 PM Roundtable Discussion With Audience Q&A
Peripheral Vascular Intervention: State of the Art Accreditation: CME/CNE
Sunday, October 11 12:00 PM - 6:00 PM Room: Moscone West, 2nd Floor, Room 2006 - 2008
Session I. Lower-Extremity Intervention: SFA and Popliteal, Part 1 12:00 PM - 1:24 PM Moderators: Gary M. Ansel, Michael R. Jaff Discussants: Ori Ben-Yehuda, John R. Laird Jr, Francesco Liistro, Lindsay S. Machan, Sahil A. Parikh, Ravish Sachar
12:00 PM Is Peripheral Vascular Intervention Cost-effective? If So, From Whose Perspective? Michael R. Jaff
12:10 PM Roundtable Discussion With Audience Q&A
12:12 PM PAR-1 Antagonists and P2Y12 Inhibitors: What Are the Data and the Place of These Medications in the PAD Population (for Secondary Cardiovascular Prevention and PAD Itself)? Ori Ben-Yehuda
12:22 PM Roundtable Discussion With Audience Q&A 12:24 PM Everything You Wanted to Know About Endovascular Radiation Hazards but Were Afraid to Ask Lindsay S. Machan
12:34 PM Roundtable Discussion With Audience Q&A
12:36 PM Peering Through the Veil: Outcomes Reporting in SFA Intervention Decoded William A. Gray
12:46 PM Roundtable Discussion With Audience Q&A
12:48 PM Review of Multicenter, Randomized Outcomes Data of Antiproliferative Therapies: Zilver PTX, LEVANT II, In.PACT SFA, and DEFINITIVE AR Ravish Sachar
12:58 PM Roundtable Discussion With Audience Q&A
1:00 PM Review and Perspectives of the Global Registry Data for Antiproliferative Therapies John R. Laird Jr
1:10 PM Roundtable Discussion With Audience Q&A
1:12 PM Evolving Endovascular Treatment Strategies for Femoral-Popliteal Disease in a DES and DCB World Gary M. Ansel
1:22 PM Roundtable Discussion With Audience Q&A
Session II. Lower-Extremity Intervention: SFA and Popliteal, Part 2 1:24 PM - 2:36 PM Moderators: Prakash Krishnan, Mahmood K. Razavi Discussants: J. Dawn Abbott, J. Michael Bacharach, Eric J. Dippel, Lawrence A. Garcia, Mark J. Goodwin, Christopher D. Owens
1:24 PM Update on Bioresorbable Scaffolds for PAD Mahmood K. Razavi
1:34 PM Roundtable Discussion With Audience Q&A
1:36 PM Adventitial Injection Therapy for Restenosis: Rationale and Clinical Results to Date Christopher D. Owens
1:46 PM Roundtable Discussion With Audience Q&A
1:48 PM Biomimetic Stents: Rationale and Current Clinical Results Eric J. Dippel
1:58 PM Roundtable Discussion With Audience Q&A
2:00 PM A Master Class in Atherectomy: Choices, Strategies, and Execution Prakash Krishnan
2:10 PM Roundtable Discussion With Audience Q&A 2:12 PM Debulking in the Antiproliferative Era: Which Patient Is Most Likely to Benefit? Lawrence A. Garcia
2:22 PM Roundtable Discussion With Audience Q&A
2:24 PM Lithoplasty in Calcified SFA Lesions: Update on Outcomes and Future Trials Todd J. Brinton
2:34 PM Roundtable Discussion With Audience Q&A
Session III. Lower-Extremity Intervention: SFA and Popliteal, Part 3 2:36 PM - 3:48 PM Moderators: Hans Krankenberg, Lindsay S. Machan Discussants: Herbert D. Aronow, Paul T.L. Chiam, Roger Gammon, Luis A. Guzman, R. Stefan Kiesz, Francesco Liistro, Bruno Scheller
2:36 PM Has the TASC Classification Scheme Been Made Obsolete by Today’s Antiproliferative Therapeutics? Lindsay S. Machan
2:46 PM Roundtable Discussion With Audience Q&A
2:48 PM OCT-Guided CTO Crossing and Atherectomy: Are There Advantages of Image-Guided Intervention? Roger Gammon
2:58 PM Roundtable Discussion With Audience Q&A
3:00 PM Access Alternatives in Long SFA Disease Andrej Schmidt
3:10 PM Roundtable Discussion With Audience Q&A
3:12 PM Embolic Protection in Lower-Extremity Intervention: Where Does It Make the Most Sense? Venkatesh Ramaiah
3:22 PM Roundtable Discussion With Audience Q&A
3:24 PM Management Strategies for SFA/Popliteal In-Stent Restenosis Hans Krankenberg
3:34 PM Roundtable Discussion With Audience Q&A
3:36 PM Two US PAD Trials That May Well Change Your Practice: Updates on the ENDOMAX and LIBERTY-360 Studies Herbert D. Aronow
3:46 PM Roundtable Discussion With Audience Q&A
Session IV. Critical Limb Ischemia and Infrapopliteal Intervention 3:48 PM - 5:12 PM Moderators: J. A. Mustapha, Craig M. Walker Discussants: Gary M. Ansel, Osamu Iida, Thomas O. McNamara, Andrej Schmidt, Mehdi H. Shishehbor, Christopher K. Zarins
3:48 PM The Team Approach to Critical Limb Ischemia: Who, How, and Why? Alex Powell
3:58 PM Roundtable Discussion With Audience Q&A
4:00 PM Perfusion Assessment in Critical Limb Ischemia in 2015 Mehdi H. Shishehbor
4:10 PM Roundtable Discussion With Audience Q&A
4:12 PM The BEST-CLI Study: Rationale and Update Ehrin J. Armstrong
4:22 PM Roundtable Discussion With Audience Q&A
4:24 PM What the Device Approval Trials Will Tell Us About the Endovascular Approach to CLI – and What They Won’t Gary M. Ansel
4:34 PM Roundtable Discussion With Audience Q&A
4:36 PM To Angiosome or Not to Angiosome? That Is the Question Osamu Iida
4:46 PM Roundtable Discussion With Audience Q&A
4:48 PM Approaching the Critical Limb Ischemia Endovascular Procedure: Planning Access, Tools, and Goals Craig M. Walker
4:58 PM Roundtable Discussion With Audience Q&A
5:00 PM Advanced CLI BTK Intervention: Two Cases From a Master Level Operator Case Presenter: Andrej Schmidt
5:10 PM Roundtable Discussion With Audience Q&A
Session V. Venous Disease and Renal Intervention 5:12 PM - 6:00 PM Moderators: Anthony J. Comerota, Mahmood K. Razavi Discussants: Mark J. Goodwin, Michel Camille Henry, Lindsay S. Machan, Venkatesh Ramaiah
5:12 PM Current State of Renal Stenting: Data and Indications for Intervention Sahil A. Parikh
5:22 PM Roundtable Discussion With Audience Q&A
5:24 PM Update on the Approach to DVT Management: When to Intervene and How? Anthony J. Comerota 5:34 PM Roundtable Discussion With Audience Q&A
5:36 PM Acute PE Management in the Real World: Observations From a Successful Broad- Based Experience Mark J. Goodwin
5:46 PM Roundtable Discussion With Audience Q&A
5:48 PM Chronic Thromboembolic Pulmonary Hypertension (CTEPH): Frequency and Approaches to Management Matthew D. Bacchetta
5:58 PM Roundtable Discussion With Audience Q&A
Renal Denervation and Hypertension Therapies Accreditation: CME/CNE
Sunday, October 11 12:00 PM - 6:00 PM Room: Moscone West, 3rd Floor, Room 3006 - 3008
Session I. Update on Device-Based Therapies for Hypertension Treatment 12:00 PM - 1:10 PM Moderators: Ajay J. Kirtane, Felix Mahfoud Discussants: Michael Böhm, Darrel P. Francis, Thomas F. Luscher, Farrell O. Mendelsohn, Michael A. Weber, William B. White
12:00 PM Uncontrolled Hypertension: Prevalence, Prognosis, and Treatment Michael A. Weber
12:10 PM Device-Based Therapies for Hypertension Treatment: Procedural Aspects Farrell O. Mendelsohn
12:20 PM Myths as to Why SYMPLICITY HTN-3 Failed Darrel P. Francis
12:40 PM Unresolved Issues and the Path Moving Forward Felix Mahfoud
12:50 PM Roundtable Discussion With Audience Q&A
Session II. Renal Denervation: Do New Anatomical Insights Dictate Procedural Changes? 1:10 PM - 2:30 PM Moderators: Juan F. Granada, Michael Joner Discussants: Henning Kelbæk, Felix Mahfoud, James R. Margolis, Farrell O. Mendelsohn, Robert S. Schwartz, Renu Virmani, Robert L. Wilensky 1:10 PM Nerve Distribution Along the Renal Arteries: From the Branches to the Ostium Michael Joner
1:18 PM Roundtable Discussion With Audience Q&A
1:22 PM Procedural Parameters for Successful Renal Denervation: Anything on the Horizon? Michael Böhm
1:31 PM Roundtable Discussion With Audience Q&A
1:35 PM Lesion Characteristics From the Different Devices: Do They Differ? Juan F. Granada
1:43 PM Roundtable Discussion With Audience Q&A
1:47 PM Time to Revise Treatment Recommendations: Go Distal and Into the Branches Justin E. Davies
1:55 PM Roundtable Discussion With Audience Q&A
2:00 PM Influence of Arterial Microanatomy on Response to Renal Artery Catheter Energy Denervation Elazer R. Edelman
2:08 PM Roundtable Discussion With Audience Q&A
2:12 PM Putting It All Together: Procedural Recommendations in 2015 Krishna J. Rocha-Singh
2:20 PM Roundtable Discussion With Audience Q&A
Session III. Device-Based Therapies for Hypertension and Beyond: The Path Forward 2:30 PM - 4:05 PM Moderators: Farrell O. Mendelsohn, William B. White Discussants: Michael Böhm, Melvin D. Lobo, John A. Ormiston, Michael A. Weber, Adam Witkowski
2:30 PM Considerations and Recommendations for Future Clinical Trials in Device-Based Hypertension Treatments William B. White
2:40 PM Roundtable Discussion With Audience Q&A
2:50 PM Update on Medtronic’s Spyral Global Michael Böhm
2:57 PM Update on Boston Scientific’s REINFORCE Michael A. Weber
3:04 PM Roundtable Discussion With Audience Q&A
3:14 PM Update on St. Jude’s Trial William A. Gray 3:21 PM Recor’s Trial Program Laura Mauri
3:28 PM Roundtable Discussion With Audience Q&A
3:38 PM Keynote Lecture: If I Had Uncontrolled Hypertension… Horst Sievert
3:50 PM Roundtable Discussion With Audience Q&A
Session IV. Device-Based Therapies: Novel and Investigational Approaches for Hypertension Treatment 4:05 PM - 6:00 PM Moderators: C. Venkata S. Ram, Krishna J. Rocha-Singh, Thomas Zeller Discussants: Steven L. Almany, Justin E. Davies, Sameer Gafoor, Michael Jonas, Stephen G. Worthley
4:05 PM Kona Noninvasive Therapy System Roland E Schmieder
4:15 PM Roundtable Discussion With Audience Q&A
4:20 PM Denervx Microwave for Denervation Stefan C. Bertog
4:30 PM Roundtable Discussion With Audience Q&A
4:35 PM Nonvascular Renal Denervation (Verve) Richard R. Heuser
4:45 PM Roundtable Discussion With Audience Q&A
4:50 PM Ablative Solutions (Chemical Neurolysis) Wojtek Wojakowski
5:00 PM Roundtable Discussion With Audience Q&A
5:05 PM Baroreceptor Stimulation: CVRx and Beyond Atul Pathak
5:15 PM Roundtable Discussion With Audience Q&A
5:20 PM Mobius HD: A Self-Expanding Carotid Implant Farrell O. Mendelsohn
5:30 PM Roundtable Discussion With Audience Q&A
5:35 PM Rox: Percutaneous Fistula Creation Krishna J. Rocha-Singh
5:45 PM Roundtable Discussion With Audience Q&A STEMI, Shock, and Cardiac Arrest: Breakthrough Discoveries, Unsettled Issues, and Emerging Approaches Accreditation: CME/CNE
Sunday, October 11 12:00 PM - 6:18 PM Room: Moscone West, 2nd Floor, Room 2014 - 2018
Session I. STEMI 2015 Hot Topic 1: Multivessel Disease Treatment 12:00 PM - 12:50 PM Moderators: Thomas Engstroem, Barry D. Rutherford Discussants: Eric R. Bates, Rajesh M. Dave, Kishore J. Harjai, Elmir Omerovic, Miodrag C. Ostojic, David A. Wood
12:00 PM Introduction: A Critical Appraisal of Culprit Only vs Multivessel Intervention in STEMI – Targets, Guidance, Data Review, and Future Directions Shamir R. Mehta
12:08 PM Updated Meta-analysis of Culprit Only vs Complete Revascularization in STEMI: Are We Impacting Death and Reinfarction or Repeat Revascularization Only? Anthony H. Gershlick
12:14 PM Should FFR Be Used Routinely in STEMI Patients With Multivessel Disease, and Is It Reliable During the Index and/or Staged Procedures? Colin Berry
12:20 PM Nonculprit Lesions in STEMI Patients With Multivessel Disease: Is the Issue Ischemia or Vulnerable Plaque? David Erlinge
12:26 PM Impact of CTO Revascularization After Primary PCI for AMI: Is This Where the Benefit Lies? David Antoniucci
12:32 PM Roundtable Discussion With Audience Q&A
12:40 PM Case Introduction: A STEMI Patient With Multivessel Disease Henning Kelbæk
12:43 PM Roundtable Discussion: How Should We Treat?
12:47 PM Case Resolution: How Did We Treat Our STEMI Patient With Multivessel Disease (and What Were the Long-term Outcomes)? Henning Kelbæk
Session II. STEMI 2015 Hot Topic 2: Pharmacotherapy 12:50 PM - 2:07 PM Moderators: C. Michael Gibson, Marco Valgimigli Discussants: Robert A. Byrne, Michel R. Le May, Goran K. Olivecrona, Francesco Pelliccia, Michael J. Rinaldi, Jorge F. Saucedo
12:50 PM Is the Debate Over? Bivalirudin in STEMI Data Synthesis (HORIZONS-AMI, EUROMAX, HEAT-PPCI, BRIGHT, and MATRIX) Philippe Gabriel Steg
1:00 PM Roundtable Discussion With Audience Q&A
1:05 PM Pre-debate 1 Vote: Should Cangrelor or an Oral ADP Antagonist Be Used in Most STEMI Patients? Poll Moderators: C. Michael Gibson, Marco Valgimigli
1:07 PM Debate 1: Should Cangrelor or an Oral ADP Antagonist Be Used in Most STEMI Patients? The Mechanism and Data Support Cangrelor! Harvey D. White
1:13 PM Debate 1: Should Cangrelor or an Oral ADP Antagonist Be Used in Most STEMI Patients? Oral or Crushed Ticagrelor for All! Guido Parodi
1:19 PM Debate 1: Should Cangrelor or an Oral ADP Antagonist Be Used in Most STEMI Patients? Prasugrel for Primary PCI Is Simplest and Best! Sigmund Silber
1:25 PM Roundtable Discussion With Audience Q&A
1:31 PM Post-debate 1 Vote (Who Won?): Debate – Should Long-term (2 Years to Life) Dual Antiplatelet Therapy Be Used in Most Patients After MI? Poll Moderators: C. Michael Gibson, Marco Valgimigli
1:33 PM Pre-debate 2 Vote: Should Long-term (2 Years to Life) Dual Antiplatelet Therapy Be Used in Most Patients After MI? Poll Moderators: C. Michael Gibson, Marco Valgimigli
1:35 PM Debate 2: Should Long-term (2 Years to Life) Dual Antiplatelet Therapy Be Used in Most Patients After MI? Yes, and the Data Are Strong for Clopidogrel and Prasugrel (DAPT Trial)! Robert W. Yeh
1:41 PM Debate 2: Should Long-term (2 Years to Life) Dual Antiplatelet Therapy Be Used in Most Patients After MI? Yes, and the Data Are Strong for Ticagrelor (PEGASUS Trial)! Neal S. Kleiman
1:47 PM Debate 2: Should Long-term (2 Years to Life) Dual Antiplatelet Therapy Be Used in Most Patients After MI? Yes, and Vorapaxar Should Be Considered! Ori Ben-Yehuda
1:53 PM Debate 2: Should Long-term (2 Years to Life) Dual Antiplatelet Therapy Be Used in Most Patients After MI? Slow Down, Excess Bleeding, and No Mortality Benefit? Primum Non Nocere and Save Costs! Tullio Palmerini
1:59 PM Roundtable Discussion With Audience Q&A
2:05 PM Post-debate 2 Vote (Who Won?): Should Long-term (2 Years to Life) Dual Antiplatelet Therapy Be Used in Most Patients After MI? Poll Moderators: C. Michael Gibson, Marco Valgimigli
Session III. STEMI 2015 Hot Topics 3, 4, and 5: Radial Intervention, Thrombus Management, and Stent Technology 2:07 PM - 3:26 PM Moderators: Dariusz Dudek, Robert J. de Winter Discussants: Rabin dra Nath Chakraborty, Vladimir Dzavik, Vasim Farooq, Chaim S. Lotan, Massimo Napodano
2:07 PM Is the Debate Over? Routine Thrombus Aspiration in STEMI (From TAPAS to INFUSE- AMI to TASTE to TOTAL) Stefan K. James
2:17 PM Has the Case for Radial Intervention in STEMI Been Proven Beyond Doubt? The Case for and Against (an Internal Debate) Ajay J. Kirtane
2:27 PM Roundtable Discussion With Audience Q&A
2:35 PM Specialized Stents in STEMI: MGuard – From MASTER I to MASTER II Gregg W. Stone
2:43 PM Bioresorbable Scaffolds in STEMI: Rationale and 1-Year TROFI II Results Patrick W. Serruys
2:50 PM Outcomes After Contemporary DES in STEMI: Glass Half Full or Half Empty? Tullio Palmerini
2:56 PM Five-Year Results From the EXAMINATION Trial Manel Sabate
3:02 PM Rationale for and Design of HORIZONS-ABSORB Gregg W. Stone
3:09 PM Roundtable Discussion With Audience Q&A
3:16 PM Case Introduction: A STEMI Patient With Abundant Thrombus Arif Al Nooryani
3:19 PM Roundtable Discussion: How Should We Treat?
3:23 PM Case Resolution: How Did We Treat Our STEMI Patient With Abundant Thrombus (and What Were the Long-term Outcomes)? Arif Al Nooryani
Session IV. Prehospital Management and Systems of Care 3:26 PM - 4:36 PM Moderators: Timothy D. Henry, Philippe Gabriel Steg Discussants: Sreenivas Arramraju Kumar, Michel R. Le May, Sameer Mehta, Duane S. Pinto, Ivan C. Rokos, Theodore L. Schreiber 3:26 PM Description of the Ideal STEMI Network, Prehospital Care Directives, and Emergency Room Processes: Lessons Learned Over the Last 20 Years Hadley K. Wilson
3:34 PM Latest Insights From Mission Lifeline: False Activations, Use of Nonguideline-Directed Medical Therapies, and More Alice K. Jacobs
3:41 PM New Insights From the Stent for Life Initiative Petr Kala
3:48 PM What Is Optimal Prehospital Pharmacotherapy for STEMI in 2015? Duane S. Pinto
3:55 PM A Fresh Look at the Pharmacoinvasive Strategy Eric R. Bates
4:02 PM Is Deferred Stenting an Option? Rationale for the DEFER-STEMI Trial Colin Berry
4:09 PM Telemedicine and Artificial Intelligence to Optimize STEMI Outcomes: The Brazil Experience Roberto Botelho
4:15 PM Improving Door-in-Door-out in STEMI Transfer: The Last Frontier Christopher B. Granger
4:21 PM TCTMD Global PCI Mapping Project: Description and Goals Ivan C. Rokos
4:26 PM Roundtable Discussion With Audience Q&A
Session V. Cardiogenic Shock and Cardiac Arrest 4:36 PM - 5:25 PM Moderators: Cindy L. Grines, Simon Redwood Discussants: Jose P.S. Henriques, Petr Kala, Roger J. Laham, Michael Mooney, Nico H.J. Pijls, Christian M. Spaulding
4:36 PM Recommendations for an Emergent Invasive Approach in the Resuscitated Comatose Patient Tanveer Rab
4:44 PM What Do We Really Achieve With Hypothermia in Cardiac Arrest? Insights From TTM and Randomized Trials Michel R. Le May
4:51 PM The Spectrum of Hemodynamic Support Options for Cardiogenic Shock II: Are Any of Them Useful (Data Review and Personal Perspectives)? Holger Thiele 5:01 PM Support for Hemodynamically Severe RV Infarction: Impella RP, TandemHeart, and CentriMag William W. O'Neill
5:08 PM Establishing ECMO in the Severe Shock and Cardiac Arrest Patient: Practical Issues and Patient Outcomes Hiroo Takayama
5:15 PM Roundtable Discussion With Audience Q&A
Session VI. Novel Approaches for Myocardial Salvage 5:25 PM - 6:18 PM Moderators: Robert A. Kloner, William W. O'Neill Discussants: William T. Abraham, Giuseppe Biondi-Zoccai, Stephen G. Ellis, Christopher B. Granger, Jan J. Piek, Bernhard Witzenbichler
5:25 PM The Spectrum of Failed Pharmacologic and Biologic Approaches to Enhance Myocardial Salvage: Review and Personal Perspectives Bernard J. Gersh
5:33 PM The Effect of the Mitochondrial Protective Agent Bendavia on Infarct Size, Left Ventricular Remodeling, and Left Ventricular Function C. Michael Gibson
5:40 PM Impact of Cyclosporine in STEMI: The CIRCUS Trial Michel Ovize
5:47 PM Can Peri-infarct Pacing Prevent Adverse Left Ventricular Remodeling After Large MI? From MENDMI to PRomPT Gregg W. Stone
5:54 PM Pressure-Controlled Intermittent Coronary Sinus Occlusion (PICSO) to Reduce Infarct Size in STEMI Azfar G. Zaman
6:01 PM An Intracoronary Injectable Bioabsorbable Scaffold to Treat Left Ventricular Remodeling Uwe Zeymer
6:08 PM Roundtable Discussion With Audience Q&A
Transcatheter Aortic Valve Therapies: Today and Tomorrow, Part 1 Accreditation: CME/CNE
Sunday, October 11 12:00 PM - 6:00 PM Room: Moscone West, 3rd Floor, Room 3007 - 3011 Session I. TAVR 2015: Evolving Perspectives 12:00 PM - 1:45 PM Moderators: Eberhard Grube, Michael J. Mack Discussants: Elazer R. Edelman, A. Pieter Kappetein, Martin B. Leon, Ganesh Manoharan, Ian T. Meredith, Craig R. Smith, John G. Webb
12:00 PM Introduction Martin B. Leon
12:05 PM TAVR is a Breakthrough Technology: Important Milestones and Emerging Controversies Raj Makkar
12:15 PM Pioneer’s Corner: Reflections on the Impact of TAVR on Aortic Valve Therapy (Now and in the Future) – The Cardiac Surgeon’s Perspective Michael J. Mack
12:20 PM Pioneer’s Corner: Reflections on the Impact of TAVR on Aortic Valve Therapy (Now and in the Future) – The Noninvasive Cardiologist’s Perspective Robert O. Bonow
12:25 PM Pioneer’s Corner: Reflections on the Impact of TAVR on Aortic Valve Therapy (Now and in the Future) – The Interventional Cardiologist’s Perspective Eberhard Grube
12:30 PM Roundtable Discussion With Audience Q&A
12:35 PM Debate: Fate of the Multidisciplinary Heart Valve Team as TAVR Becomes a “TF-First” Minimalist Procedure – That Would Be a Mistake! A. Pieter Kappetein
12:40 PM Debate: Fate of the Multidisciplinary Heart Valve Team as TAVR Becomes a “TF-First” Minimalist Procedure – Inevitable Decline! Ganesh Manoharan
12:45 PM Roundtable Discussion With Audience Q&A
12:50 PM Which Patients for TAVR? Will Surgical Risk Stratification Remain the Dominant Strategy in the Future? John G. Webb
1:00 PM Roundtable Discussion With Audience Q&A
1:05 PM “New” TAVR Technology Synthesis: Stabilized or Still Evolving? What’s Hot (and What’s Not)? And My Favorite Accessories! Ian T. Meredith
1:15 PM Roundtable Discussion With Audience Q&A
1:25 PM KEYNOTE LECTURE: Redefining Aortic Stenosis – Use of Advanced Imaging, Hemodynamics, Computational Models, and Clinical Data to Revise Trigger Points for Treatment Elazer R. Edelman 1:40 PM Roundtable Discussion With Audience Q&A
Session II. TAVR 2015: Clinical Indications 1:45 PM - 3:50 PM Moderators: Martin B. Leon, Neil E. Moat Discussants: Danny Dvir, Howard C. Herrmann, Axel Linke, Nicolo Piazza, Simon Redwood, Patrick W. Serruys, Alec S. Vahanian, Thomas Walther, John G. Webb
1:45 PM What Are the Indications for TAVR in 2015? According to the EU and US Guidelines Alec S. Vahanian
1:50 PM What Are the Indications for TAVR in 2015? According to “Real-World” Clinical Practice Axel Linke
1:55 PM Which Aortic Stenosis Patients Are Definitely NOT TAVR Candidates in 2015? Thomas Walther
2:00 PM Roundtable Discussion With Audience Q&A
2:05 PM The Case for TAVR Expansion to Lower-Risk Patients Nicolo Piazza
2:15 PM Roundtable Discussion With Audience Q&A
2:20 PM Status Update on Moderate-Risk TAVR RCTs 1: PARTNER IIA Martin B. Leon
2:25 PM Status Update on Moderate-Risk TAVR RCTs 2: SURTAVI Patrick W. Serruys
2:30 PM Predicting the Future of Open Surgery for Aortic Stenosis: The “TAVR Effect” Neil E. Moat
2:40 PM Roundtable Discussion With Audience Q&A
2:45 PM KEYNOTE LECTURE: Transcatheter Valve Replacement for Bioprosthetic Valve Failure – Gold Standard vs Selective Application (The VIVID Registry) Danny Dvir
3:00 PM Roundtable Discussion With Audience Q&A
3:05 PM Status Updates on New TAVR Indications 1: Bicuspid Aortic Valve Disease John G. Webb
3:12 PM Status Updates on New TAVR Indications 2: Low-Flow (Low-Gradient) AS Howard C. Herrmann
3:19 PM Status Updates on New TAVR Indications 3: Aortic Stenosis + Coronary Artery David Hildick-Smith
3:26 PM Status Updates on New TAVR Indications 4: Aortic Stenosis + Mitral Regurgitation Simon Redwood
3:33 PM Status Updates on New TAVR Indications 5: Predominant Aortic Regurgitation Hendrik Treede
3:40 PM Roundtable Discussion With Audience Q&A
Session III. TAVR Evidence-Based Medicine: The Latest Clinical Data 3:50 PM - 6:00 PM Moderators: Samir R. Kapadia, Jeffrey J. Popma Discussants: Mohamed Abdel-Wahab, Marco Barbanti, Darshan Doshi, Martin B. Leon, Axel Linke, Neil E. Moat, Michael J. Reardon, Lars Sondergaard, Thomas Walther
3:50 PM Updates From the US CoreValve Studies 1: Follow-up From the Extreme and High-Risk Subgroups Michael J. Reardon
4:00 PM Updates From the US CoreValve Studies 2: Reports From Selected Substudies Jeffrey J. Popma
4:10 PM Roundtable Discussion With Audience Q&A
4:15 PM Updates From the PARTNER Trials 1: Follow-up From the Inoperable and High-Risk Subgroups Samir R. Kapadia
4:25 PM Updates From the PARTNER Trials 2: Reports From Selected Substudies Darshan Doshi
4:35 PM Roundtable Discussion With Audience Q&A
4:40 PM Lessons From the EU TAVR Registries 1: ADVANCE Axel Linke
4:47 PM Lessons From the EU TAVR Registries 2: The UK Registry Neil E. Moat
4:54 PM Lessons From the EU TAVR Registries 3: FRANCE 2 (and More) Martin B. Leon
5:01 PM Lessons From the EU TAVR Registries 4: GARY (Surgery and TAVR) Thomas Walther
5:08 PM Lessons From the EU TAVR Registries 5: Italian Registries and OBSERVANT Marco Barbanti
5:15 PM Roundtable Discussion With Audience Q&A
5:25 PM Other Important TAVR Studies 1: Updates From the TVT Registry John D. Carroll
5:34 PM Other Important TAVR Studies 2: The NOTION All-Comer TAVR RCT Lars Sondergaard
5:43 PM Other Important TAVR Studies 3: CHOICE – Late Follow-up Mohamed Abdel-Wahab
5:50 PM Roundtable Discussion With Audience Q&A
Transcatheter Mitral Valve Therapies: Today and Tomorrow, Part 1 Accreditation: CME/CNE
Sunday, October 11 12:00 PM - 6:10 PM Room: Moscone West, 3rd Floor, Room 3014 - 3018
Session I. Mitral Regurgitation: The Big Picture 12:00 PM - 1:25 PM Moderators: Patrick T. O'Gara, Allan Schwartz Discussants: William T. Abraham, Robert O. Bonow, Jeffrey S. Borer, David L. Brown, Catherine M. Otto, Mark Reisman, Renu Virmani
12:00 PM A Pathologic Understanding of the Mitral Valve Complex Renu Virmani
12:07 PM A Bioskills Primer for Mitral Valve Device Inventors and Interventionalists Mark Reisman
12:15 PM The Current Epidemiology and Treatment of Mitral Valvular Regurgitation in the US and EU Jeffrey S. Borer
12:21 PM Epidemiology and Treatment of Mitral Valvular Regurgitation: What We Don't Know That We Should! Alec S. Vahanian
12:27 PM Medical Therapy for Mitral Regurgitation: Does Anything Work? Patrick T. O'Gara
12:34 PM How Effective Is CRT in Reducing MR? William T. Abraham
12:41 PM What’s New in the Guidelines? Catherine M. Otto
12:49 PM What’s Controversial or Unsettled in the Guidelines? Robert O. Bonow
12:57 PM The Mitral Valve Heart Team: How to Make This More Than a Concept David L. Brown 1:02 PM The New MVARC Consensus Documents: Take-home Messages Gregg W. Stone
1:10 PM Roundtable Discussion With Audience Q&A
Session II. Mitral Regurgitation Core Concepts: Imaging 1:25 PM - 2:26 PM Moderators: Robert J. Siegel, Neil J. Weissman Discussants: Paul A. Grayburn, Samir R. Kapadia, Jonathon A. Leipsic, Stamatios Lerakis, James K. Min, Luc A Pierard
1:25 PM Step-by-Step Approach to Assessing MR: An Integrative Approach Neil J. Weissman
1:32 PM Nuances of DMR vs FMR Imaging and Quantification Robert J. Siegel
1:39 PM 3-D Imaging Is Crucial for Mitral Valve Assessment and Interventional Guidance Samir R. Kapadia
1:45 PM Exercise-Induced MR: Prognosis and Practicality Luc A Pierard
1:51 PM Emerging Role of CT for Assessment of Mitral Valve Anatomy and Dysfunction Jonathon A. Leipsic
1:58 PM Should MRI Be the New Gold Standard for Mitral Imaging and MR Quantification? Paul A. Grayburn
2:05 PM A Futuristic Imaging Vision for Mitral Valve Diagnosis and Intervention Guidance James K. Min
2:11 PM Roundtable Discussion With Audience Q&A
Session III. Mitral Regurgitation: Evolution of Surgical Therapy 2:26 PM - 3:55 PM Moderators: Michael J. Mack, Patrick M. McCarthy Discussants: David H. Adams, Khalil Fattouch, James S. Gammie, Robert A. Guyton, Ruediger Lange, Allan Schwartz, Christina Vassileva
2:26 PM How Good Can Surgical Outcomes Be in Primary MR? The Expert Surgeon’s Perspective David H. Adams
2:33 PM How Good Can Surgical Outcomes Be in Secondary MR? The Expert Surgeon’s Perspective Patrick M. McCarthy 2:40 PM Acute and Late Results After Surgical Repair and Replacement of Degenerative MR James S. Gammie
2:48 PM The Real-World Practice of Surgery in Primary and Secondary MR: Outcomes in the Medicare Population Christina Vassileva
2:55 PM The Real-World Practice of Surgery in Primary and Secondary MR: European Insights Ruediger Lange
3:02 PM Residual and Recurrent MR After MV Repair and Replacement: What Is the Data (for Primary vs Secondary MR)? Allan Schwartz
3:10 PM Beyond the Undersized Ring for Secondary MR: Adjunctive Techniques for Repair Khalil Fattouch
3:17 PM Do Different Rings Really Make a Difference in Primary MR? In Secondary MR? Robert A. Guyton
3:24 PM Pre-debate Vote: Should Most Patients Undergoing Surgery for Secondary MR Have Mitral Valve Repair or Replacement? Poll Moderators: Michael J. Mack, Patrick M. McCarthy
3:26 PM Debate: Repair vs Replacement for Secondary MR: Repair Always! Khalil Fattouch
3:32 PM Debate: Repair vs Replacement for Secondary MR: Replacement Always! Michael J. Mack
3:38 PM Post-debate Vote (Who Won?): Should Most Patients Undergoing Surgery for Secondary MR Have Mitral Valve Repair or Replacement? Poll Moderators: Michael J. Mack, Patrick M. McCarthy
3:40 PM Roundtable Discussion With Audience Q&A
Session IV. Mitral Regurgitation: New MitraClip Evidence and Knowledge 3:55 PM - 5:06 PM Moderators: Stephan Baldus, Scott Lim Discussants: Colin M. Barker, Raoul Bonan, John D. Carroll, Eric A. Cohen, David W.M. Muller, Daniel Suerder, Molly Szerlip, David X. Zhao
3:55 PM Update on Ongoing MitraClip Randomized Trials Gregg W. Stone
4:02 PM Five-Year Randomized EVEREST II Results: Where MitraClip Shined (and Where It Didn’t) Ted E. Feldman
4:09 PM Essential Lessons From the EVEREST Registries: High Risk, Realism, and Others Saibal Kar 4:16 PM Updated MitraClip Outcomes From the STS TVT Registry (and Comparison With EU Registries) Gorav Ailawadi
4:23 PM What Has the European MitraClip Sentinel Registry Taught Us? Carlo Di Mario
4:30 PM TRAMI Registry MitraClip Updates: Outcomes in Primary vs Secondary MR, the Learning Curve, and More Stephan Baldus
4:37 PM GRASP Registry Updates: Outcomes in EVEREST Eligible vs Ineligible Patients and More Carmelo Grasso
4:44 PM The MitraSwiss Registry: Updated 6 and 12 Month Results Daniel Suerder
4:51 PM Roundtable Discussion With Audience Q&A
Session V. Mitral Regurgitation: Case Decision Making 5:06 PM - 6:10 PM Moderators: Khalil Fattouch, James B. Hermiller Jr Discussants: Michael Argenziano, Vinayak Bapat, Saibal Kar, Wesley R. Pedersen, Paul Sorajja, Thomas Walther
5:06 PM Pre-debate Vote: Should MitraClip Be Offered to Primary MR Patients at Intermediate Surgical Risk With Optimal MitraClip Anatomy? Poll Moderators: Khalil Fattouch, James B. Hermiller Jr
5:08 PM Debate: The Intermediate Surgical Risk Patient With P2 Prolapse – The Case for MV Surgery! Michael Argenziano
5:14 PM Debate: The Intermediate Surgical Risk Patient With P2 Prolapse – The Case for MitraClip! Saibal Kar
5:20 PM Roundtable Discussion With Audience Q&A
5:25 PM Post-debate Vote (Who Won?): Should MitraClip Be Offered to Primary MR Patients at Intermediate Surgical Risk With Optimal MitraClip Anatomy? Poll Moderators: Khalil Fattouch, James B. Hermiller Jr
5:27 PM I Placed a MitraClip in This Low-Risk Primary MR Patient With These Results: Does the Panel Agree? Saibal Kar
5:33 PM Roundtable Discussion With Audience Q&A 5:36 PM I Performed Surgery in This Intermediate-Risk Patient With Isolated Secondary MR With These Results: Does the Panel Agree? Thomas Walther
5:42 PM Roundtable Discussion With Audience Q&A
5:45 PM Examples of Cases Where MV Surgery for MR Failed (and Reasons Why) Vinayak Bapat
5:52 PM Examples of Cases Where MitraClip Failed (and Reasons Why) James B. Hermiller Jr
5:59 PM Roundtable Discussion With Audience Q&A
24th Annual Cardiovascular Nurse and Technologist Symposium, Part 2 Accreditation: CNE
Sunday, October 11 8:00 AM - 5:50 PM Room: Moscone North, Lower Level, Room 135
Session I. Transcatheter Aortic Valve Therapies 8:00 AM - 10:00 AM Moderator: Marian C. Hawkey Discussants: Philipp Blanke, Katie Della Mora, Kathryn Fidlow, Samir R. Kapadia, Sandra Lauck, Ganesh Manoharan, Ian T. Meredith
8:00 AM Welcome and Introduction Marian C. Hawkey
8:05 AM Current TAVR Landscape Ian T. Meredith
8:20 AM Neuroprotection During TAVR Samir R. Kapadia
8:30 AM Predictors and Clinical Outcomes of Permanent Pacemaker Implantation After TAVR Ganesh Manoharan
8:40 AM Case Presentations/Taped TAVR Case Segments Moderator: Marian C. Hawkey Case Presenter: Samir R. Kapadia Discussants: Ganesh Manoharan, Ian T. Meredith
8:55 AM Roundtable Discussion With Audience Q&A
9:10 AM TAVR Clinical Pathways: Individualized Plans of Care Sandra Lauck 9:20 AM Five by Five: TAVR Lean Initiatives Katie Della Mora
9:30 AM The Basics of Interventional Imaging of Aortic Stenosis: Echo and CT Philipp Blanke
9:40 AM Clinical Research to Clinical Practice: Tracking Real-world Outcomes With the TVT Registry Kathryn Fidlow
9:50 AM Roundtable Discussion With Audience Q&A Moderator: Marian C. Hawkey Discussants: Philipp Blanke, Katie Della Mora, Kathryn Fidlow, Sandra Lauck
Session II. Transcatheter Mitral Valve Therapies 10:00 AM - 10:30 AM Moderator: Sarah Clarke Discussants: Anita Asgar, Joachim Schofer
10:00 AM Current TMVR Landscape: MitraClip and Beyond Joachim Schofer
10:10 AM MitraClip Case Presentation Case Presenter: Anita Asgar
10:20 AM Roundtable Discussion With Audience Q&A
Session III. Founder’s Session 10:30 AM - 11:00 AM Moderator: Marvin L. Woodall Discussant: Julio C. Palmaz
10:30 AM Keynote Lecture: What It Was Like to Discover the Stent: “A Personal Journey” Julio C. Palmaz
10:55 AM Roundtable Discussion With Audience Q&A
Session IV. Peripheral/Carotid Intervention 11:00 AM - 12:00 PM Moderator: Julie Logan Discussants: George L Adams, Jacqueline Gamberdella, Roger Gammon, William A. Gray, Krishna J. Rocha-Singh, Craig M. Walker, James P. Zidar
11:00 AM Why Is It So Complex? Simplifying Lower-Extremity Disease Michael R. Jaff
11:10 AM Debate: For SFA Disease I Prefer a Drug-Eluting Stent! William A. Gray
11:18 AM Debate: For SFA Disease I Prefer a Drug-Coated Balloon With Provisional Bare-Metal Stenting George L Adams
11:26 AM Do We Need to Reevaluate Our PTA Technique? Lessons Learned From Drug-Eluting Balloons Krishna J. Rocha-Singh
11:34 AM Role of Atherectomy in Lower-Extremity Disease Roger Gammon
11:42 AM Below-the-Knee Disease: Salvaging the Limb Craig M. Walker
11:50 AM Discussion
Lunch 12:00 PM - 12:30 PM
Session V. Take the Cath Lab Challenge 12:30 PM - 1:30 PM
12:30 PM Introduction of Session Sarah Clarke
12:34 PM Round 1: Twenty Questions Moderator: Martina Kelly Speight
1:04 PM Round 2 (the Top 3 Players): Five Questions Moderator: Julie Logan
1:24 PM Crown the Winner! Moderator: Russell A. Brandwein
Session VI. Bioresorbable Scaffolds: Setting the Stage 1:30 PM - 2:00 PM Moderator: Thomas H. Maloney Discussants: David G. Rizik, Ron Waksman
1:30 PM What Are Bioresorbable Scaffolds (BRS), and Why Do We Need Them? Ron Waksman
1:40 PM BRS Results to Date: Imaging, Randomized Trials, and Anticipation of ABSORB III David G. Rizik
1:52 PM Roundtable Discussion With Audience Q&A Session VII. Dual Antiplatelet Therapy Duration Debate 2:00 PM - 2:30 PM Moderator: Regina Deible Discussants: Gennaro Giustino, Daniel I. Simon
2:00 PM Introduction: Why Is This Issue Important? Ischemia vs Bleeding Roxana Mehran
2:05 PM Debate: The Case for Long-term DAPT After Stenting In Most Patients! Daniel I. Simon
2:15 PM Debate: The Case for Short-term DAPT in Most Patients! Gennaro Giustino
2:25 PM Roundtable Discussion With Audience Q&A
Session VIII. Complex High-Risk Interventional Procedures (CHIP) 2:30 PM - 4:45 PM Moderator: Martina Kelly Speight
2:30 PM What Is CHIP? Sunil V. Rao
2:40 PM Preparing the Lab for CHIP (Including Disaster Planning) Donna Dasinger
2:50 PM High-Risk PCI With Hemodynamic Support Megan M Kenninson
3:00 PM Roundtable Discussion With Audience Q&A Moderator: Martina Kelly Speight Discussants: Donna Dasinger, Megan M Kenninson, Sunil V. Rao
3:10 PM Edited Taped Case: Calcified Left Main Bifurcation Case Case Presenter: Margaret B. McEntegart
3:25 PM Edited Taped Case: Complex CTO – Antegrade Dissection and Reentry and Retrograde Case Presenter: J. Aaron Grantham
3:35 PM Setting Up a Successful CTO Program From the Nurse-Tech Perspective Dan Hornberger
3:45 PM Two Primary PCI STEMI Cases With Cardiogenic Shock Case Presenter: Michael J. Lim
3:55 PM STEMI and Cardiogenic Shock: It's Not Just About the PCI Jason Lucas 4:05 PM Edited Taped Case: CHIP With a Complication Case Presenter: Philippe Généreux
4:20 PM Roundtable Discussion Moderator: Martina Kelly Speight Discussants: J. Aaron Grantham, Philippe Généreux, Dan Hornberger, Michael J. Lim, Jason Lucas, Margaret B. McEntegart
Session IX. Left Atrial Appendage Closure 4:45 PM - 5:50 PM Moderator: Russell A. Brandwein Discussants: Steven L. Goldberg, Elizabeth M Perpetua, Brian K. Whisenant, Steven J. Yakubov
4:45 PM What Is the Left Atrial Appendage, and Why Is It So Important? Russell A. Brandwein
4:55 PM Warfarin and the New Oral Anticoagulant Options for Atrial Fibrillation Steven L. Goldberg
5:05 PM How Good Is LAA Closure Compared to Oral Anticoagulants? Results of Studies Elizabeth M Perpetua
5:15 PM Stroke and Bleeding Risk Scores: How to Use These in Practice Brian K. Whisenant
5:25 PM Step-by-Step Review of LAA Procedures (Watchman and Lariat) Steven J. Yakubov
5:40 PM Roundtable Discussion With Audience Q&A
iASSESS, Day 1 - Sunday, Oct. 11 Accreditation: CME
Sunday, October 11 8:00 AM - 6:00 PM Room: Moscone South, Lower Level, Room 103
iASSESS, Day 1: Morning Session 8:00 AM - 12:00 PM Moderators: Tayo A. Addo, George D. Dangas
8:00 AM Radial Access and Related Complications Moderator: Samir B. Pancholy Jordan Safirstein 8:30 AM Statistics and Clinical Study Design: Teaching Through Example Moderator: Stuart J. Pocock Binita Shah
9:15 AM Complications Related to Contrast, Commonly Used Medications, and Radiation Exposure Moderator: Giora Weisz Payam Dehghani
10:00 AM Femoral Access and Related Complications Moderator: Jose M. Wiley Arnold Seto
10:30 AM Stable Angina: PCI vs CABG vs OMT Moderator: George D. Dangas Robert T. Pyo
11:15 AM NSTE-ACS: Risk Stratification and Treatment Moderator: Emmanouil S. Brilakis Dmitriy N. Feldman
Break 12:00 PM - 1:00 PM
iASSESS, Day 1: Afternoon Session 1:00 PM - 6:00 PM Moderators: Emmanouil S. Brilakis, Manish A. Parikh
1:00 PM STEMI: Treatment Strategies, Drugs, and Devices Moderator: Tayo A. Addo Dharam J. Kumbhani
2:00 PM Bare-Metal and Drug-Eluting Stents: Devices, Indications, and Outcomes Moderator: Emmanouil S. Brilakis Rajesh V Swaminathan
3:00 PM Restenosis and Stent Thrombosis Moderator: George D. Dangas Ehrin J. Armstrong
4:00 PM Complex Coronary Lesions (Left Main, Bifurcations, CTO, and SVGs) Moderator: George D. Dangas Tayo A. Addo
5:00 PM Antithrombin Therapy and GP IIb/IIIa Inhibitors in Patients With ACS and in Those Undergoing PCI Moderator: Frederick Feit Sripal Bangalore Bioresorbable Scaffolds: Lessons From Early European Registries Presented by Coronary Atheroma and Interventional Cardiology Group (GACI), The Czech Working Group of Interventional Cardiology, Working Group of the German Society of Cardiology, and the Polish Association of Cardiovascular Interventions Accreditation: none
Sunday, October 11 1:00 PM - 2:30 PM Room: Moscone North, Lower Level, Room 131
Bioresorbable Scaffolds: Lessons From Early European Registries 1:00 PM - 2:30 PM Moderators: George D. Dangas, Eric Van Belle Discussants: René Koning, Maciej Lesiak, Martin Maly, Richard J. Rapoza, Jens Wiebe
1:00 PM USA Presents: Scaffold-Vessel Interactions: What the Interventionalist Should Know Richard J. Rapoza
1:15 PM France Presents: French Absorb Registry – Indications and In-Hospital Results René Koning
1:30 PM Czech Republic Presents: The ACS Patient – Czech Republic Registry Martin Maly
1:45 PM Germany Presents: The Diabetic Patient – German Registry Jens Wiebe
2:00 PM Poland Presents: The CTO Patient – Polish Registry Maciej Lesiak
2:15 PM Roundtable Discussion With Audience Q&A
2:25 PM Conclusions and Take-home Messages Eric Van Belle
Mitral Valve Interventions Presented by Moroccan Society of Cardiology, Qatar Cardiovascular Research Center, and Algerian Society of Cardiology Accreditation: none
Sunday, October 11 1:00 PM - 2:30 PM Room: Moscone North, Lower Level, Room 133
Mitral Valve Interventions 1:00 PM - 2:30 PM Moderators: Mohamed Chettibi, Ziyad M. Hijazi Discussants: Dounia Ben Zaroual, Nassime Zaoui 1:00 PM Role of Echo Imaging in the Selection of Patient Dounia Ben Zaroual
1:10 PM Transeptal Puncture for Mitral Valve Interventions: Indications and Techniques Mohamed Chettibi
1:20 PM Roundtable Discussion With Audience Q&A
1:30 PM Mitral Valvuloplasty: Current Indications, Techniques, and Results Dounia Ben Zaroual
1:40 PM An Illustrative Case of Mitral Valvuloplasty Case Presenter: Nassime Zaoui
1:50 PM My Nightmare Mitral Valve Case Ziyad M. Hijazi
2:02 PM Roundtable Discussion With Audience Q&A
2:12 PM Paravalvar Mitral Leak Closure: Indications, Devices, and an Illustrative Case Case Presenter: Ziyad M. Hijazi
2:22 PM Roundtable Discussion With Audience Q&A
Complex Coronary and Peripheral Vascular Interventions Presented by the Saudi Arabian Cardiac Interventional Society (SACIS), Iranian Society of Interventional Cardiology (ISOIC), Interventional Council of The Cardiac Society of Australia and New Zealand (CSANZ), Emirate Group on Interventional Cardiology (EGIC), and the Tunisian Working Group on Interventional Cardiology (GTCI) Accreditation: none
Sunday, October 11 3:00 PM - 4:30 PM Room: Moscone North, Lower Level, Room 133
Session I. Cases From Saudi Arabia 3:00 PM - 3:23 PM Moderators: Mirvat Alasnag, Habib Gamra, Abdullah Shehab Discussants: Owayed Al Shemmari, Thierry Corcos, Mahmoud Hashemian
3:00 PM Use of a Novel Reentry Device for a Peripheral CTO Case Presenter: Mirvat Alasnag
3:09 PM Use of a Reentry Device for a Coronary CTO With Bioresorbable Scaffolds Case Presenter: Waqar H. Ahmed
3:18 PM Roundtable Discussion With Audience Q&A Session II. Cases From Tunisia 3:23 PM - 3:46 PM Moderators: Mirvat Alasnag, Habib Gamra, Abdullah Shehab Discussants: Owayed Al Shemmari, Thierry Corcos, Mahmoud Hashemian
3:23 PM Primary PCI for STEMI in a 19-Year-Old Pregnant Patient With Cardiogenic Shock Case Presenter: Kais BATTIKH
3:32 PM STEMI With Left Main Occlusion and Cardiac Arrest Case Presenter: Mehdi MS Slim
3:41 PM Roundtable Discussion With Audience Q&A
Session III. A Case From the United Arab Emirates 3:46 PM - 4:00 PM Moderators: Mirvat Alasnag, Habib Gamra, Abdullah Shehab Discussants: Owayed Al Shemmari, Thierry Corcos, Mahmoud Hashemian
3:46 PM Bioresorbable Scaffolds in a Bifurcation During Primary PCI Case Presenter: Abdullah Shehab
3:55 PM Roundtable Discussion With Audience Q&A
Session IV. A Case From Iran 4:00 PM - 4:14 PM Moderators: Mirvat Alasnag, Habib Gamra Discussants: Owayed Al Shemmari, Thierry Corcos, Mahmoud Hashemian, Abdullah Shehab
4:00 PM CTO of a Right Coronary Artery via the LIMA Case Presenter: Saeed Alipour Parsa
4:09 PM Roundtable Discussion With Audience Q&A
Session V. A Case From Australia 4:14 PM - 4:30 PM Moderators: Mirvat Alasnag, Habib Gamra, Abdullah Shehab Discussants: Owayed Al Shemmari, Thierry Corcos, Mahmoud Hashemian
4:14 PM CTO PCI: An Australian Experience Case Presenters: Ravinay Bhindi, James Sapontis
4:23 PM Roundtable Discussion With Audience Q&A What Is Your Best Strategy for Treatment of Multivessel CAD? Presented by the Danish Working Group on Interventional Cardiology, the Canadian Association of Interventional Cardiology, Korean Society of Interventional Cardiology, and the Vietnam National Heart Association Accreditation: none
Sunday, October 11 3:00 PM - 5:00 PM Room: Moscone North, Lower Level, Room 131
Session I. PCI vs CABG in Multivessel Disease: A Classic but Still Ongoing Debate 3:00 PM - 3:30 PM Moderators: Taehoon Ahn, Robert C. Welsh Discussants: Young-Hak Kim, Samer Mansour, Quang Ngoc Nguyen, Manh-Hung Pham, Christian Juhl Terkelsen, Leif Thuesen
3:00 PM Current Guideline Update Manh-Hung Pham
3:07 PM Outcomes Have Always Been Better With CABG Samer Mansour
3:14 PM PCI May Be Considered in Challenging Patients With Triple-Vessel Disease Young-Hak Kim
3:21 PM Roundtable Discussion With Audience Q&A
Session II. Hybrid Coronary Revascularization in MVD 3:30 PM - 4:00 PM Moderators: Taehoon Ahn, Robert C. Welsh Discussants: Young-Hak Kim, Samer Mansour, Quang Ngoc Nguyen, Manh-Hung Pham, Christian Juhl Terkelsen, Leif Thuesen
3:30 PM The Case for Hybrid Revascularization: Combining the LIMA With the LAD With Stenting of Non-LAD Lesions Leif Thuesen
3:37 PM Hybrid Revascularization Strategy for AMI Patients: How to Apply Christian Juhl Terkelsen
3:44 PM Role of Bioresorbable Vascular Scaffolds in a Hybrid Revascularization Strategy Quang Ngoc Nguyen
3:51 PM Roundtable Discussion With Audience Q&A
Session III. PCI Strategy in Multivessel Disease 4:00 PM - 4:30 PM Moderators: Thomas Engstroem, Manh-Hung Pham Discussants: Kevin Bainey, Henning Kelbæk, Chang-Wook Nam, Nhan Thanh Vo, David A. Wood, Cheol Woong Yu 4:00 PM Complete vs Incomplete Revascularization David A. Wood
4:07 PM One-Stage vs Delayed PCI for Non–culprit Lesion in Patients With AMI and Multivessel Disease Henning Kelbæk
4:14 PM How to Apply Physiology-Guided PCI for MVD Chang-Wook Nam
4:21 PM Roundtable Discussion With Audience Q&A
Session IV. Case-Based Learning: PCI in Multivessel Disease 4:30 PM - 5:00 PM Moderators: Thomas Engstroem, Manh-Hung Pham, Nhan Thanh Vo Discussants: Kevin Bainey, Henning Kelbæk, Chang-Wook Nam, David A. Wood, Cheol Woong Yu
4:30 PM A Practical Stenting Issue in Multivessel Disease: When and Where to Stop? With Case Examples Kevin Bainey
4:37 PM PCI for Multivessel Disease With CTO: When and How? With Case Examples Cheol Woong Yu
4:44 PM PCI for Multivessel Disease in the CABG Candidate: Should We Follow the Guidelines? With Case Examples Minh Vo
4:51 PM Roundtable Discussion With Audience Q&A
Featured Session for International Advisory Faculty: China Meets India – Practice Patterns in Modern Interventional Cardiology Accreditation: none
Sunday, October 11 10:00 AM - 12:00 PM Room: Moscone West, Level 3, 3014 - 3018
China Meets India: Practice Patterns in Modern Interventional Cardiology 10:00 AM - 12:00 PM Moderators: Ajay J. Kirtane, Gary S. Mintz, Manish A. Parikh, Bo Xu Discussants: YunDai Chen, Guosheng Fu, B.K. Goyal, Sreenivas Arramraju Kumar, Sundeep Mishra, Debabrata Mukherjee, Manotosh Panja, Bin Zhang, Qi Zhang
10:00 AM Introductions and Welcome Ajay J. Kirtane
10:05 AM Special Lecture: Retrograde CTO PCI – From Inception to Current Practice Lei Ge
10:17 AM Discussion
10:20 AM Complex PCI Case Presentation: Indications to Treatment Manish A. Parikh
10:28 AM Discussion
10:32 AM Advisory Faculty Surveys With Q&A on Complex PCI
10:52 AM STEMI Case Presentation With MVD: From Presentation Through Discharge Sreenivas Arramraju Kumar
11:00 AM Discussion
11:04 AM Advisory Faculty Surveys With Q&A on STEMI
11:24 AM NSTE-ACS Case Presentation: From Presentation Through Discharge Qi Zhang
11:32 AM Discussion
11:36 AM Advisory Faculty Surveys With Q&A on NSTE-ACS
11:56 AM Moderator Summary
The Argentine College of Interventional Cardiologists (CACI) at TCT: Left Main Revascularization – Current Perspective and Beyond Accreditation: none
Sunday, October 11 6:30 PM - 8:00 PM Room: Moscone South, Lower Level, Room 104
The Argentine College of Interventional Cardiologists (CACI) at TCT Left Main Revascularization: Current Perspective and Beyond 6:30 PM - 8:00 PM Moderators: Alejandro Cherro, Arturo José Fernández Murga, Alfredo E. Rodriguez Discussants: Jorge H. Leguizamon, Ruben A. Piraino, Gustavo Samaja
6:30 PM Introduction Arturo José Fernández Murga
6:34 PM Tips and Tricks During Left Main PCI: Rationality for "Guided" PCI Hugo F. Londero
6:44 PM Case Presentation: Guided Left Main PCI Jorge A. Baccaro
6:51 PM Roundtable Discussion With Audience Q&A
7:01 PM Complete vs Incomplete Revascularization After Left Main PCI: Does an Open RCA Matter? David Antoniucci
7:11 PM Case Presentation: Left Main With a RCA CTO Anibal A. Damonte
7:18 PM Roundtable Discussion With Audience Q&A
7:28 PM Stretching the Left Main PCI Limits With Latest-Generation DES and BVS Alaide Chieffo
7:38 PM Case Presentation : A Highly Complex Left Main PCI Diego D Grinfeld
7:45 PM Roundtable Discussion With Audience Q&A
7:55 PM Summary and Closing Remarks Alfredo E. Rodriguez
Bangla Interventional Therapeutics (BIT)@TCT Accreditation: none
Sunday, October 11 6:30 PM - 8:30 PM Room: Moscone North, Lower Level, Room 123
Welcome and Introductory Remarks 6:30 PM - 6:35 PM Afzalur Rahman
Session I. Transcatheter Aortic Valve Intervention 6:35 PM - 7:30 PM Moderators: Alain G. Cribier, Afzalur Rahman Discussants: Rabin dra Nath Chakraborty, Helene Eltchaninoff, Angela Hoye, Kaisar Nasrullah Khan
6:35 PM TAVI: Why I Prefer a Balloon-Expandable Valve! Alain G. Cribier
6:47 PM TAVI: My Choice Is a Self-Expanding Valve Hendrik Treede
6:59 PM How to Simplify the TAVI Procedure Helene Eltchaninoff 7:11 PM Roundtable Discussion With Audience Q&A
7:21 PM TAVI: Consensus and Take-home Messages Alain G. Cribier
Session II. Left Main Bifurcation PCI 7:30 PM - 8:30 PM Moderators: Rabin dra Nath Chakraborty, Angela Hoye Discussants: Debasis Ghosh, Afzalur Rahman
7:30 PM Provisional Stenting of Distal Left Main: One Stent Only? Afzalur Rahman
7:42 PM Medina 1, 1, 1 of the Distal Left Main: Are 2 Stents Needed? Rabin dra Nath Chakraborty
7:54 PM Roundtable Discussion With Audience Q&A
8:00 PM Complex Left Main Case 1 Case Presenter: Kaisar Nasrullah Khan
8:10 PM Complex Left Main Case 2 Case Presenter: Prakas Chandra Mandal
8:20 PM Left Main Bifurcation PCI: Consensus and Take-home Messages Angela Hoye
8:25 PM Closing Remarks Rabin dra Nath Chakraborty
China Interventional Therapeutics in Partnership With TCT: Best of CIT 2015 Accreditation: none
Sunday, October 11 6:30 PM - 8:30 PM Room: Moscone South, Lower Level, Room 102
Session I. Left Main and Bifurcation PCI 6:30 PM - 7:10 PM Moderators: Run-Lin Gao, Gregg W. Stone, Bo Xu Discussants: Philippe Généreux, Yaling Han, Shubin Qiao, Lefeng Wang, Weimin Wang
6:30 PM How Should I Treat a Patient With a Distal Left Main Bifurcation and Intermediate Syntax Score? Zening Jin 6:35 PM How Would I Treat a Patient With a Distal Left Main Bifurcation and Intermediate Syntax Score? Jian Liu
6:40 PM How Did I Treat a Patient With Distal a Left Main Bifurcation and Intermediate Syntax Score? Zening Jin
6:45 PM Use of Appropriate Bifurcation Techniques: Chinese Perspectives Shao-Liang Chen
6:55 PM Roundtable Discussion With Audience Q&A
Session II. Transcatheter Aortic Valve Replacement 7:10 PM - 7:50 PM Moderators: Run-Lin Gao, Martin B. Leon, Bo Xu Discussants: Hasan Jilaihawi, Horst Sievert, Jian'an Wang, Mathew Williams
7:10 PM How Should I Treat a High Surgical Risk Patient With Bicuspid Aortic Valve Stenosis? Yongjian Wu
7:15 PM How Would I Treat a High Surgical Risk Patient With Bicuspid Aortic Valve Stenosis? Mao Chen
7:20 PM How Did I Treat a High Surgical Risk Patient With Bicuspid Aortic Valve Stenosis? Yongjian Wu
7:25 PM Development of TAVR in China: Clinical Data and Experience Yuejin Yang
7:35 PM Roundtable Discussion With Audience Q&A
Session III. Chronic Total Occlusions 7:50 PM - 8:30 PM Moderators: Run-Lin Gao, Dimitri Karmpaliotis, Bo Xu Discussants: Jiyan Chen, Guosheng Fu, William L. Lombardi, Etsuo Tsuchikane, Bin Zhang
7:50 PM How Should I Treat a Patient With a Severe Calcified Chronic Total Occlusion? Lei Ge
7:55 PM How Would I Treat a Patient With a Severe Calcified Chronic Total Occlusion? Qi Zhang
8:00 PM How Did I Treat a Patient With a Severe Calcified Chronic Total Occlusion? Lei Ge
8:05 PM Use of Appropriate CTO Techniques: Chinese Perspectives Jiyan Chen 8:15 PM Roundtable Discussion With Audience Q&A
GISE at TCT: Complications During Coronary and Structural Disease Interventions Accreditation: none
Sunday, October 11 6:30 PM - 8:00 PM Room: Moscone North, Lower Level, Room 121
Session I. Complications During Left Main PCI 6:30 PM - 7:16 PM Moderators: Francesco Bedogni, Gennaro Sardella Discussants: Gian Battista Danzi, Javier Escaned, Goran Stankovic
6:30 PM Introduction and Objectives Gennaro Sardella
6:32 PM Case 1 Introduction: A Major Complication During Left Main PCI Case Presenter: Alaide Chieffo
6:37 PM Roundtable Discussion With Audience Q&A
6:49 PM Case 1 Resolution: How We Treated Our Patient Case Presenter: Alaide Chieffo
6:54 PM Case 2 Introduction: A Major Complication During Left Main PCI Case Presenter: Francesco Burzotta
6:59 PM Roundtable Discussion With Audience Q&A
7:11 PM Case 2 Resolution: How We Treated Our Patient Case Presenter: Francesco Burzotta
Session II. Complications During and After MitraClip Implantation 7:16 PM - 8:00 PM Moderators: Francesco Bedogni, Sergio Berti Discussants: Carmelo Grasso, Joachim Schofer
7:16 PM Case 3 Introduction: A Complication During MitraClip Implantation Case Presenter: Olaf Franzen
7:21 PM Roundtable Discussion With Audience Q&A
7:33 PM Case 3 Resolution: How We Treated Our Patient Case Presenter: Olaf Franzen 7:38 PM Case 4 Introduction: A Complication After MitraClip Implantation Case Presenter: Gennaro Sardella
7:43 PM Roundtable Discussion With Audience Q&A
7:55 PM Case 4 Resolution: How We Treated Our Patient Case Presenter: Gennaro Sardella
JIM at TCT 2015 Accreditation: none
Sunday, October 11 6:30 PM - 8:30 PM Room: Moscone North, Lower Level, Room 125
Session I. Complex Cases and Problem Solving in TAVR 6:30 PM - 7:30 PM Moderators: Carlo Di Mario, Eberhard Grube Discussants: Samir R. Kapadia, Azeem Latib, Augusto D. Pichard, Didier Tchetche
6:30 PM Case 1: Difficult TAVR Access/Delivery Case Presenter: Augusto D. Pichard
6:40 PM Case 2: A TAVR Complication Case Presenter: Azeem Latib
6:50 PM Case 3: A TAVR Complication Case Presenter: Didier Tchetche
7:00 PM Self-Expanding vs Balloon-Expandable TAVR: Pros and Cons Samir R. Kapadia
7:15 PM Roundtable Discussion With Audience Q&A
Session II. Bioresorbable Scaffolds: Will They Replace Metallic Stents? 7:30 PM - 8:30 PM Moderators: Carlo Di Mario, Eberhard Grube Discussants: Azeem Latib, Manel Sabate, Daniel I. Simon, Nicolas M. Van Mieghem
7:30 PM Case 1: A Case Where BVS Was Preferred Over Metallic DES Case Presenter: Azeem Latib
7:40 PM Case 2: A Case Where Metallic DES Was Preferred Over BVS Case Presenter: Nicolas M. Van Mieghem 7:50 PM Debate: Will Bioresorbable Scaffolds Replace Metallic Stents in the Majority of Cases? YES! Manel Sabate
8:00 PM Debate: Will Bioresorbable Scaffolds Replace Metallic Stents in the Majority of Cases? NO! Daniel I. Simon
8:10 PM Roundtable Discussion With Audience Q&A
SOLACI in Partnership With TCT Accreditation: none
Sunday, October 11 6:30 PM - 8:30 PM Room: Moscone North, Lower Level, Room 130
Session I. Coronary Intervention: Evidence-Based Medicine and Case-Based Knowledge 6:30 PM - 7:38 PM Moderators: Ricardo Lluberas, Roxana Mehran, Jamil Abdalla Saad Discussants: Jorge Gaspar, Hugo F. Londero, Jose Armando Mangione, Alexandre Schaan Quadros
6:30 PM Opening Remarks and A Tribute to Liliana Grinfeld Moderators: Roxana Mehran, Jamil Abdalla Saad
6:35 PM Which Patients With Multivessel Disease and Diabetes Do I Treat With PCI, and How? Expedito E. Ribeiro
6:42 PM Roundtable Discussion With Audience Q&A
6:46 PM Who Receives Bioresorbable Scaffolds in My Practice, and What Are My Tips and Tricks? Roberto Botelho
6:54 PM Roundtable Discussion With Audience Q&A
6:59 PM Three to Six Months of DAPT Is My Practice Even in Very Complex Cases: Here’s Why Fausto Feres
7:07 PM Roundtable Discussion With Audience Q&A
7:12 PM Routine IVUS and FFR: Is It Really Worth It? Fernando Cura
7:20 PM Roundtable Discussion With Audience Q&A
7:25 PM How to Achieve 90% Success in Treating CTO Lesions Emmanouil S. Brilakis 7:33 PM Roundtable Discussion With Audience Q&A
Session II. TAVR: Preventing Complications 7:38 PM - 8:30 PM Moderators: Ricardo Lluberas, Roxana Mehran, Jamil Abdalla Saad Discussants: Jorge Gaspar, Hugo F. Londero, Jose Armando Mangione, Alexandre Schaan Quadros
7:38 PM Is Cerebral Protection Necessary? Alexandra J. Lansky
7:46 PM Roundtable Discussion With Audience Q&A
7:51 PM Late Applications in TAVR Antonio Enrique Dager
7:59 PM Roundtable Discussion With Audience Q&A
8:04 PM How to Prevent Annular Rupture, Coronary Occlusion, and Permanent Pacemakers Oscar A. Mendiz
8:12 PM Roundtable Discussion With Audience Q&A
8:17 PM Top 10 Lessons for Complication-Free TAVR Philippe Généreux
8:25 PM Roundtable Discussion With Audience Q&A
TCT Asia Pacific (TCTAP): Imaging vs Physiology for LM and Non-LM Bifurcation PCI Accreditation: none
Sunday, October 11 6:30 PM - 8:30 PM Room: Moscone South, Lower Level, Room 103
Session I. Left Main and Non–Left Main PCI 6:30 PM - 7:26 PM Moderators: Gary S. Mintz, Seung-Jung Park, Gregg W. Stone Discussants: Jung-Min Ahn, Soo-Jin Kang, Young-Hak Kim
6:30 PM Welcome and Introductory Remarks Moderator: Seung-Jung Park
6:32 PM Use of FFR and IVUS for Left Main PCI Gary S. Mintz
6:42 PM Use of FFR and IVUS for Non–Left Main Bifurcation PCI Soo-Jin Kang 6:52 PM Use of FFR and IVUS for Long and Tandem Lesions PCI Jung-Min Ahn
7:02 PM Update of PCI vs CABG for Left Main PCI (Beyond SYNTAX, PRECOMBAT, BEST, and Meta-analysis 2015): What's Different From 3-Vessel Disease? Seung-Jung Park
7:12 PM Non–Left Main Bifurcation PCI: Insight From CROSS, PERFECT, and DK CRUSH Trials Young-Hak Kim
7:22 PM Roundtable Discussion With Audience Q&A
Session II. Vulnerable Plaque 7:26 PM - 8:10 PM Moderators: Gary S. Mintz, Seung-Jung Park, Gregg W. Stone Discussants: Akiko Maehara, Nico H.J. Pijls
7:26 PM How to Define Vulnerable Plaque? What Does It Mean? Akiko Maehara
7:36 PM Functionally Insignificant Vulnerable Plaque: Just Defer It! Nico H.J. Pijls
7:46 PM I Want to Treat Vulnerable Plaques: Not Today but Tomorrow (From PROSPECT to PROSPECT ABSORB) Gregg W. Stone
7:56 PM We Need More Data: STABLE and PREVENT Seung-Jung Park
8:06 PM Roundtable Discussion With Audience Q&A
Session III. The Master Class: Case Reviews 8:10 PM - 8:30 PM Moderators: Gary S. Mintz, Seung-Jung Park, Gregg W. Stone Discussants: Jung-Min Ahn, Marie-Claude Morice
8:10 PM A Complex Left Main Bifurcation Case Presenter: Marie-Claude Morice
8:16 PM Roundtable Discussion With Audience Q&A
8:20 PM A Complex Non–Left Main Bifurcation: Function vs Morphology Jung-Min Ahn
8:26 PM Roundtable Discussion With Audience Q&A TCT India Next 2015 Session at TCT “Complex & High Risk PCI" Accreditation: none
Sunday, October 11 6:30 PM - 8:30 PM Room: Moscone North, Lower Level, Room 120
Left Main & Bifurcations 6:30 PM - 7:15 PM Moderators: Praveer Agarwal, Amal Kumar Banerjee, Narenda N. Khanna, Ajay J. Kirtane, Lekha R.A. Pathak, N. Prathapkumar
6:30 PM Left Main Intervention – When to Intervene & How to Optimize Outcomes N. Prathapkumar
6:45 PM Case Presentation 1: Restenosis in LM Bifurcation Stenting Case Presenter: Rajesh Vijayvergiya
6:53 PM Discussion
6:55 PM Case Presentation 2: IVUS guided LM Intervention Case Presenter: Sreenivas Arramraju Kumar
7:03 PM Discussion
7:05 PM Case Presentation 3: LM Bifurcation Gokul M. Reddy
7:13 PM Discussion
Nightmares in the Cath Lab 7:15 PM - 8:30 PM Moderators: Praveer Agarwal, Praveen Chandra, Ajay J. Kirtane, Sreenivas Arramraju Kumar, Brian V Pinto, Pratap C. Rath, Shireesh P Sathe
7:15 PM Chasing Migrating/Potentially Embolic Large RA Thrombi Narenda N. Khanna
7:25 PM Leak in Collateral Vessel During Retrograde PCI Pravin K Goel
7:35 PM LAD Rupture During RTA Presenting As Acute Anterior Myocardial Infarction Shiv Kumar
7:45 PM Cardiac Arrest Patients – Resuscitation to Revascularization Sreenivas Arramraju Kumar
7:55 PM Huge Thrombus Burden During PCI Ajit Menon 8:05 PM Role of Cardiac Assist Devices in Critically Sick Heart Failure Patients Needing During PCI Sundeep Mishra
8:15 PM Roundtable Discussion with Q&A
TCT Russia: A Case-Based Symposium on Technical Approaches to Complex Cardiovascular Interventions Accreditation: none
Sunday, October 11 6:30 PM - 8:30 PM Room: Moscone North, Lower Level, Room 122
TCT Russia: A Case-Based Symposium on Technical Approaches to Complex Cardiovascular Interventions 6:30 PM - 8:30 PM Moderators: Bagrat Alekyan, Juan F. Granada Discussants: Jacques Busquet, William A. Gray, Jeffrey W. Moses, Corrado Tamburino, Nir Uriel, Narek Zakaryan
6:30 PM Interventional Management of “No-Option” Coronary Artery Disease Case Presenter: Bagrat Alekyan
6:38 PM Editorial Comment (Without Slides) and Roundtable Discussion With Audience Q&A Jeffrey W. Moses
6:48 PM Hybrid Repair of a Complex Thoracoabdominal Aneurysm Case Presenter: Sergey A. Abugov
6:56 PM Editorial Comment (Without Slides) and Roundtable Discussion With Audience Q&A Jacques Busquet
7:06 PM LAA Closure Dislodgment and Bailout Approach Case Presenter: Evgeny V. Merkulov
7:14 PM Editorial Comment (Without Slides) and Roundtable Discussion With Audience Q&A William A. Gray
7:24 PM Percutaneous Approach to a Complex Thoracic Aortic Aneurysm Case Presenter: Alexey Protopopov
7:32 PM Editorial Comment (Without Slides) and Roundtable Discussion With Audience Q&A Jacques Busquet
7:42 PM Alternative Vascular Access for Interventional Lower-Limb Intervention Case Presenter: Zaza Kavteladze 7:50 PM Editorial Comment (Without Slides) and Roundtable Discussion With Audience Q&A Narek Zakaryan
8:00 PM Retrograde Left Main Stenting Case Presenter: Alexander Grigorievich Osiev
8:08 PM Editorial Comment (Without Slides) and Roundtable Discussion With Audience Q&A Corrado Tamburino
8:18 PM ACS Intervention in Patients With Orthotopic Heart Transplantation Vladimir Ganyukov
8:26 PM Editorial Comment (Without Slides) and Roundtable Discussion With Audience Q&A Nir Uriel
TTT in Partnership With TCT: I Should Have Known Better – Learn From the Masters Accreditation: none
Sunday, October 11 6:30 PM - 8:40 PM Room: Moscone North, Lower Level, Room 124
Welcome and Introductory Remarks 6:30 PM - 6:35 PM Juey-Jen Hwang
Section I 6:35 PM - 7:35 PM Moderators: George D. Dangas, Juey-Jen Hwang Discussants: Chi-Jen Chang, Jun-Jack Cheng, Sunao Nakamura, Satoru Sumitsuji
6:35 PM Case 1: My Unpredictable Nightmare! (Un-dilatable Lesion With Balloon Rupture) Case Presenter: Man-Cai Fong
6:45 PM Why Is This Happening? And What I Would Do Differently Alan C. Yeung
6:55 PM What Actually Happened Afterwards Case Presenter: Man-Cai Fong
7:00 PM Roundtable Discussion With Audience Q&A
7:05 PM Case 2: How Can I Reach My Target? (Difficult LAD Ostial CTO Without Stump) Case Presenter: Feng-Yu Kuo
7:15 PM Why Is This Happening? And What I Would Do Differently Masahiko Ochiai
7:25 PM What Actually Happened Afterwards Case Presenter: Feng-Yu Kuo
7:30 PM Roundtable Discussion With Audience Q&A
Section II 7:35 PM - 8:35 PM Moderators: George D. Dangas, Paul Hsien-Li Kao Discussants: Ying-Hwa Chen, Chi-Hung Huang, Michael S. Lee, Wei-Hsian Yin
7:35 PM Case 3: Diamond Isn't Everything! (Difficult Rotablation With Insufficient Rotawire Landing Zone) Case Presenter: Po-Ming Ku
7:45 PM Why Is This Happening? And What I Would Do Differently Augusto D. Pichard
7:55 PM What Actually Happened Afterwards Case Presenter: Po-Ming Ku
8:00 PM Roundtable Discussion With Audience Q&A
8:05 PM Case 4: Happy Ever After or Not? (TAVR With Persistent AR) Case Presenter: Mao-Shin Lin
8:15 PM Why Is This Happening? And What I Would Do Differently Eberhard Grube
8:25 PM What Actually Happened Afterwards Case Presenter: Mao-Shin Lin
8:30 PM Roundtable Discussion With Audience Q&A
Closing Remarks 8:35 PM - 8:40 PM Paul Hsien-Li Kao
ABCs of Interventional Cardiology 2015: An Introductory Course Accreditation: CME
Sunday, October 11 8:00 AM - 12:00 PM Room: Moscone South, Lower Level, Room 104 Session I. Basics of Cardiac Anatomy and Angiography 8:00 AM - 9:30 AM Moderators: George D. Dangas, Vijay Kunadian Discussants: Ziad A. Ali, Hemal Gada, Philippe Généreux, Robert T. Pyo
8:00 AM Cardiac and Coronary Anatomy Vijay Kunadian
8:12 AM Discussion With Audience Q&A
8:15 AM Right and Left Heart Catheterization: Technique and Hemodynamics Robert T. Pyo
8:27 AM Discussion With Audience Q&A
8:30 AM Coronary Angiography 1: Basics Artifacts and Pitfalls Philippe Généreux
8:42 AM Discussion With Audience Q&A
8:45 AM Intravascular Imaging: Core Concepts Ziad A. Ali
8:57 AM Discussion With Audience Q&A
9:00 AM Coronary Artery Disease: Pathology and Pathogenesis Greg L. Kaluza
9:12 AM Discussion With Audience Q&A
9:15 AM Vascular Access Routes and Technique Robert T. Pyo
9:27 AM Discussion With Audience Q&A
Break 9:30 AM - 9:45 AM
Session II. Basics of Cardiovascular Pathophysiology 9:45 AM - 11:00 AM Moderators: Peter Barlis, Greg L. Kaluza Discussants: Ziad A. Ali, Allen Jeremias, Michael C. Kim
9:45 AM Concepts of Interventional Pharmacology Piera Capranzano
10:00 AM Coronary Pathophysiology and FFR Allen Jeremias
10:12 AM Discussion With Audience Q&A
10:15 AM Acute Coronary Syndrome: NSTEMI Ziad A. Ali
10:27 AM Discussion With Audience Q&A
10:30 AM Acute Coronary Syndrome: STEMI Michael C. Kim
10:42 AM Discussion With Audience Q&A
10:45 AM Valvular Heart Disease for the Interventionalist Nicola Corvaja
10:57 AM Discussion With Audience Q&A
Break 11:00 AM - 11:15 AM
Session III. Introduction to Coronary Angioplasty and Stenting 11:15 AM - 12:00 PM Moderators: Robert T. Pyo, Bonnie H. Weiner Discussants: Ziad A. Ali, Davide Capodanno
11:15 AM Cath Lab Room Setup and Basic Equipment (Guiding Catheters, Wires, and Balloons) Bonnie H. Weiner
11:27 AM Discussion With Audience Q&A
11:30 AM Atherotomy, Atherectomy, and Embolic Protection Davide Capodanno
11:42 AM Discussion With Audience Q&A
11:45 AM DES Systems and Outcomes Ziad A. Ali
11:57 AM Discussion With Audience Q&A
SCAI Cath Lab Boot Camp at TCT 2015 Accreditation: CME
Sunday, October 11 8:00 AM - 12:00 PM Room: Moscone South, Lower Level, Room 102
Session I. Cath Lab Leadership 8:00 AM - 9:20 AM Moderators: James C. Blankenship, Charles E. Chambers Discussant: Bernadette S. Speiser 8:00 AM It’s My First Appointment – How Do I Start? Charles E. Chambers
8:15 AM Morale in the Cath Lab: Balancing Workloads With Budgets Bernadette S. Speiser
8:30 AM Integrating the Heart Team Concept Into Cath Lab Administration James C. Blankenship
8:45 AM Conflict Resolution: Don’t Cater to the Bottom 10% Bernadette S. Speiser
9:00 AM Roundtable Discussion With Audience Q&A
Session II. Cath Lab Quality 9:20 AM - 10:40 AM Moderators: Michael A. Kutcher, Sunil V. Rao Discussants: Ralph G. Brindis, Peter L Duffy, Bonnie H. Weiner
9:20 AM Shining Light on the Sunshine Act Peter L Duffy
9:35 AM ACE and Quality: Is It Worth It for My Lab? Bonnie H. Weiner
9:50 AM How to Handle Outliers in the Lab Michael A. Kutcher
10:05 AM My AUC Scorecard Doesn’t Look Good: What Should I Do? Ralph G. Brindis
10:20 AM Roundtable Discussion With Audience Q&A
Session III. Cath Lab Economics 10:40 AM - 12:00 PM Moderators: Robert J. Applegate, Ehtisham Mahmud Discussants: James B. Hermiller Jr, Sunil V. Rao
10:40 AM Cath Lab Econ 101 Robert J. Applegate
10:55 AM TAVR and MitraClip: How Can We Afford These Products? James B. Hermiller Jr
11:10 AM Same-Day PCI: Better With the New APC Codes? Sunil V. Rao 11:25 AM Pharmacology in the Lab: Heparin or Bivalirudin? Ehtisham Mahmud
11:40 AM Roundtable Discussion With Audience Q&A
TCT International Fellows Session Accreditation: none
Sunday, October 11 5:00 PM - 6:30 PM Room: Moscone North, Lower Level, Room 131
TCT International Fellows Session 5:00 PM - 6:30 PM Moderator: George D. Dangas Discussants: Rabin dra Nath Chakraborty, Afzalur Rahman, Mohamed Sobhy, Wojtek Wojakowski, Pedro de Araujo Goncalves
5:00 PM Introduction of Top 3 Selected Winners Moderator: George D. Dangas
5:05 PM CASE 1: No Money, No Party!!! Lucia Barbieri
5:10 PM CASE 2: Tricuspid Clipping: MitraClip Device for a Congentially Corrected Transposition of Great Arteries on a Systemic Tricuspid Valve Fabien Picard
5:15 PM CASE 3: Anterograde Mitral Valve-in-Valve-in-Ring: The Solution for a Tricky Issue Gustavo Pires-Morais
5:20 PM Fellows Got Talent! (International Case Competition) Moderator: George D. Dangas
5:25 PM Case 1: Recurrent Hemoptysis: An Unusual Cause and Successful Intervention Sundar Chidambaram
5:30 PM Case 2: TAVI With PCI in a Patient With Degenerated Stentless Aortic Bioprosthesis and Reimplanted Coronaries John E Jose
5:35 PM Case 3: MitraClip in a Patient With Acute Heart Failure Associated With Dynamic Functional Mitral Regurgitation After Perioperative Myocardial Infarction Wishnu A Widodo
5:40 PM Case 4: RCA Occlusion and LMS Dissection Abdullah Sayied Abdullah 5:45 PM ARS Scoring
5:50 PM Winner Announced Moderator: George D. Dangas
6:00 PM Fellows Quiz Moderator: George D. Dangas
Monday, October 12, 2015
Main Arena I, Monday, Oct. 12 Accreditation: CME/CNE
Monday, October 12 8:00 AM - 2:00 PM Room: Moscone South, Esplanade Level, Main Arena
Plenary Session I. Live Cases 1: Bioresorbable Scaffolds 8:00 AM - 9:30 AM Live Case Moderator: Gregg W. Stone Live Case Co-Moderator: Patrick W. Serruys Live Case Discussants: Antonio L. Bartorelli, Salvatore Brugaletta, Robert A. Byrne, Bernard R. Chevalier, Michael Haude, Thomas F. Luscher, Ian T. Meredith, Manel Sabate, Ashok Seth, Pieter C. Smits, Nicolas M. Van Mieghem Digital Moderator: Dimitrios Alexopoulos Digital Panelists: Kenneth Chin, Hector M. Garcia-Garcia, Elvin Kedhi
8:00 AM San Raffaele Hospital, Milan, Italy Live Case Operators: Antonio Colombo, Francesco Giannini, MD Cosmo Godino, MD
8:45 AM A Tribute to Liliana Grinfeld Roxana Mehran
8:50 AM Institute Dante Pazzanese, São Paulo, Brazil Live Case Operators: Alexandre Abizaid, Magaly Arrais, MD, Daniel Chamié, MD, Jose de Ribamar Costa Jr, Antonio M. Kambara, MD, Dimytri Siqueira, MD Rodrigo Nieckel Da Costa, MD
Plenary Session II. TCT Opening 9:30 AM - 9:35 AM Moderators: Martin B. Leon, Gregg W. Stone
9:30 AM TCT 2015 Opening: Making Connections! Opening Video and Introductory Remarks Martin B. Leon, Gregg W. Stone Plenary Session III. Hot Topics 1: Interventional Stroke Therapy 9:35 AM - 10:05 AM Moderator: Leo Nelson Hopkins Digital Moderator: Sahil A. Parikh Digital Panelists: John D. Carroll, Alejandro Cherro, Christine Roffe, Joshua Z. Willey Discussants: Alex Abou-Chebl, Mao-Shin Lin, Klaus D. Mathias, Stephen R. Ramee, Gary S. Roubin, Adnan Siddiqui, David E. Thaler, Mark H. Wholey
9:35 AM KEYNOTE LECTURE: Acute Stroke Intervention – From Pathophysiology to Management David E. Thaler
9:50 AM Roundtable Discussion With Audience Q&A
Plenary Session IV. Clinically Oriented Case-Based Tutorial 1: Adjunctive Pharmacology 10:05 AM - 10:45 AM Moderators: Robert A. Harrington, Gregg W. Stone Digital Moderator: David J. Cohen Digital Panelists: Ori Ben-Yehuda, Bill J. French, Shamir R. Mehta, Marco Valgimigli Discussants: Deepak L. Bhatt, John A. Bittl, Dean J. Kereiakes, Laura Mauri, Francesco Pelliccia, Rod H. Stables, Philippe Gabriel Steg, Harvey D. White
10:05 AM DAPT Duration After DES: Does 1 Size Fit All? Case Presenter: John A. Bittl
10:10 AM DAPT Duration After DES: Does 1 Size Fit All? Focused Commentary John A. Bittl
10:15 AM Roundtable Discussion With Audience Q&A
10:25 AM Periprocedural Antiplatelet Therapy: Agent(s) of Choice, Oral vs IV, and Loading Strategies Case Presenter: Marco Valgimigli
10:30 AM Periprocedural Antiplatelet Therapy: Agent(s) of Choice, Oral vs IV, and Loading Strategies – Focused Commentary Roxana Mehran
10:35 AM Roundtable Discussion With Audience Q&A
Plenary Session V. Career Achievement Award 10:45 AM - 11:00 AM
10:45 AM TCT 2015 Career Achievement Award Award Presenters: Martin B. Leon, Gregg W. Stone Award Recipient: John E. Abele
Plenary Session VI. Late-Breaking Clinical Trials 1 11:00 AM - 12:00 PM Moderators: Martin B. Leon, Gregg W. Stone Digital Moderator: Ron Waksman Digital Panelists: Vincent On-Hing Kwok, Amir Lerman, David W.M. Muller, Pieter C. Smits Discussants: Stephan Achenbach, Stephen G. Ellis, Run-Lin Gao, Sanjit S. Jolly, Dean J. Kereiakes, Shigeru Saito, Patrick W. Serruys, Ashok Seth, Marco Valgimigli, Nicolas M. Van Mieghem
11:00 AM ABSORB III: A Prospective Randomized Trial of an Everolimus-Eluting Bioresorbable Scaffold vs an Everolimus-Eluting Metallic Stent in Patients With Coronary Artery Disease Dean J. Kereiakes
11:12 AM Roundtable Discussion With Audience Q&A
11:24 AM ABSORB China: A Prospective Randomized Trial of an Everolimus-Eluting Bioresorbable Scaffold vs an Everolimus-Eluting Metallic Stent in Patients With Coronary Artery Disease Run-Lin Gao
11:34 AM Roundtable Discussion With Audience Q&A
11:42 AM A Prospective Randomized Trial of Transradial vs Transfemoral Access in Patients Undergoing Coronary Angiography and Intervention Shigeru Saito
11:52 AM Roundtable Discussion With Audience Q&A
Plenary Session VII. First Report Investigations 1 12:00 PM - 12:30 PM Moderators: Dean J. Kereiakes, Ron Waksman Digital Moderator: Davide Capodanno Digital Panelists: Eric A. Cohen, Vasim Farooq, Nicolas Foin, Sreenivas Arramraju Kumar Discussants: Arif Al Nooryani, Bernard R. Chevalier, Kenneth Chin, Carlo Di Mario, Michael Haude, Jonathan M. Hill, Lisette Okkels Jensen, Elvin Kedhi, Takeshi Kimura, Jacques J. Koolen
12:00 PM ABSORB II: A Prospective Randomized Trial of an Everolimus-Eluting Bioresorbable Scaffold vs an Everolimus-Eluting Metallic Stent in Patients With Coronary Artery Disease – Two-Year Outcomes Bernard R. Chevalier
12:08 PM Roundtable Discussion With Audience Q&A
12:15 PM BIOSOLVE II: Evaluation of a Sirolimus-Eluting Bioresorbable Metallic Scaffold – Six- Month Clinical, Angiographic, and Imaging Outcomes Michael Haude
12:23 PM Roundtable Discussion With Audience Q&A
Plenary Session VIII. Live Cases 2: Valvular Heart Disease and Complex and High-Risk Interventions 12:30 PM - 2:00 PM Live Case Moderator: Martin B. Leon Live Case Co-Moderator: Alain G. Cribier Live Case Discussants: Jeroen J. Bax, David L. Brown, Charles J. Davidson, Eberhard Grube, Karel T. Koch, Ganesh Manoharan, D. Craig Miller, Michael J. Reardon, Erick Schampaert, Joachim Schofer, Robert J. Siegel, Holger Thiele Digital Moderator: Jonathan M. Hill Digital Panelists: Stanley J. Chetcuti, Marco A. Costa, Stuart J. Head, John M. Lasala
12:30 PM Cedars-Sinai Medical Center, Los Angeles, CA: TVT-TAVR/MitraClip Live Case Operators: Hasan Jilaihawi, Saibal Kar, Mehran Khorsandi, Moody Makar, Raj Makkar, Mamoo Nakamura
1:15 PM Piedmont Heart Institute/Piedmont Atlanta Hospital, Atlanta, GA: CHIP Live Case Operators: David E. Kandzari, Nicholas J. Lembo
Coronary Theater I, Monday, Oct. 12 Accreditation: CME/CNE
Monday, October 12 8:00 AM - 12:00 PM Room: Moscone North, Lower Level, Hall D
Session I. Live Cases: Left Main and Bifurcation Disease 8:00 AM - 10:00 AM Live Case Moderator: Corrado Tamburino Live Case Co-Moderator: Carlo Di Mario Live Case Discussants: Remo Albiero, Vinay K. Bahl, Carlo Briguori, Francesco Burzotta, Evald H. Christiansen, Christophe Dubois, Jens Flensted Lassen, Matti Jaakko Niemela, Tanveer Rab Digital Moderator: Robert J. Gil Digital Panelists: Jeffrey Chambers, Diego D Grinfeld, Colm Hanratty, Sasko Kedev
8:00 AM Cedars-Sinai Medical Center, Los Angeles, CA Live Case Operators: Hasan Jilaihawi, Mehran Khorsandi, Moody Makar, Raj Makkar, Mamoo Nakamura
9:00 AM San Raffaele Hospital, Milan, Italy Live Case Operators: Antonio Colombo, Francesco Giannini, MD Cosmo Godino, MD
Session II. Live Cases: Left Main and Bifurcation Disease 10:00 AM - 12:00 PM Live Case Moderator: George D. Dangas Live Case Co-Moderator: Yves R. Louvard Live Case Discussants: Bagrat Alekyan, Pawel E. Buszman, Jorge Gaspar, Angela Hoye, Ioannis Iakovou, Eustaquio Maria Onorato, Alfredo E. Rodriguez, Jamil Abdalla Saad, Gennaro Sardella, Giulio G. Stefanini Digital Moderator: Sorin J. Brener Digital Panelists: Didier Carrié, Michael S. Lee, Margaret B. McEntegart 10:00 AM Piedmont Heart Institute/Piedmont Atlanta Hospital, Atlanta, GA Live Case Operators: David E. Kandzari, Nicholas J. Lembo
11:00 AM San Raffaele Hospital, Milan, Italy Live Case Operators: Antonio Colombo, Filippo Figini, Francesco Giannini, Matteo Montofano
Structural Theater I, Monday, Oct. 12 Accreditation: CME/CNE
Monday, October 12 8:00 AM - 12:00 PM Room: Moscone North, Lower Level, Hall D
Session I. Live Cases: TAVR and MitraClip 8:00 AM - 10:00 AM Live Case Moderator: Howard C. Herrmann Live Case Co-Moderator: David W.M. Muller Live Case Discussants: Anita Asgar, Colin M. Barker, Nirat Beohar, Peter C. Block, Roger J. Laham, Helge Möllmann, Wesley R. Pedersen, Jason H. Rogers, Robert J. Siegel Digital Moderator: James B. Hermiller Jr Digital Panelists: Raoul Bonan, Sandra Lauck, Stamatios Lerakis, Duane S. Pinto
8:00 AM Columbia University Medical Center, New York, NY Live Case Operators: Isaac George, Rebecca T. Hahn, Susheel Kodali, Tamim Nazif, MD
9:00 AM Cedars-Sinai Medical Center, Los Angeles, CA Live Case Operators: Hasan Jilaihawi, MD, Saibal Kar, Mehran Khorsandi, MD, Moody Makar, MD, Raj Makkar, Mamoo Nakamura, MD
Session II. Live Cases: TAVR 10:00 AM - 12:00 PM Live Case Moderator: Ian T. Meredith Live Case Co-Moderator: Axel Linke Live Case Discussants: Jean-Claude Laborde, Georg Nickenig, Marco A. Perin, Anna Sonia Petronio, Alexey Protopopov, Afzalur Rahman, Flavio L. Ribichini, Amit Segev, Lars Sondergaard, S. Chiu Wong Digital Panelists: Roger J. Laham, Massimo Napodano, Fabian Nietlispach
10:00 AM Columbia University Medical Center, New York, NY Live Case Operators: Isaac George, Rebecca T. Hahn, Susheel Kodali, Tamim Nazif, MD
11:00 AM Institute Dante Pazzanese, São Paulo, Brazil Live Case Operators: Alexandre Abizaid, Magaly Arrais, MD, Daniel Chamié, MD, Jose de Ribamar Costa Jr, Rodrigo Nieckel Da Costa, MD, Antonio M. Kambara, MD, Dimytri Siqueira, MD
Clinical Trial Design and Interpretation, Part 2 Accreditation: CME/CNE
Monday, October 12 2:00 PM - 6:00 PM Room: Moscone West, 2nd Floor, Room 2002 - 2004
Session I. Clinical Trial Analysis: Critical Issues, Part 1 2:00 PM - 4:00 PM Moderators: Bernard J. Gersh, William S. Weintraub Discussants: Ori Ben-Yehuda, Sanjay Kaul, Spencer B. King III, Thomas F. Luscher, Debabrata Mukherjee, Jan Tijssen, Stephen D. Wiviott
2:00 PM HOT TOPIC 1: Should Small Randomized Trials Be Practice Changing? FOCUS on PRAMI and WOEST – Trialist/Guideline Perspective John A. Bittl
2:10 PM HOT TOPIC 1: Should Small Randomized Trials Be Practice Changing? FOCUS on PRAMI and WOEST – Clinician's Perspective Eric R. Bates
2:20 PM Roundtable Discussion With Audience Q&A
2:30 PM HOT TOPIC 2: Balancing Safety and Efficacy Endpoints – How Do “Net Clinical Benefit” and “Quality of Life” Fit Into the Equation? FOCUS on DAPT, PEGASUS, and MATRIX: Clinical/Trialist Perspective Gregg W. Stone
2:40 PM HOT TOPIC 2: Balancing Safety and Efficacy Endpoints – How Do “Net Clinical Benefit” and “Quality of Life” Fit Into the Equation? FOCUS on DAPT, PEGASUS, and MATRIX: Statistical Perspective Stuart J. Pocock
2:50 PM Roundtable Discussion With Audience Q&A
3:00 PM HOT TOPIC 3: How Should Trials Be Interpreted When Technology Has Moved Faster Than the Results? FOCUS on SYNTAX, COURAGE, and FREEDOM – Guideline Perspective Patrick T. O'Gara
3:10 PM HOT TOPIC 3: How Should Trials Be Interpreted When Technology Has Moved Faster Than the Results? FOCUS on SYNTAX, COURAGE, and FREEDOM – Clinician’s Perspective Ajay J. Kirtane 3:20 PM Roundtable Discussion With Audience Q&A
3:30 PM HOT TOPIC 4: Debate – Is “Big Data” the Future of Comparative-Effectiveness Analysis? Yes, the Writing Is in the Cloud! Matthew T. Roe
3:40 PM HOT TOPIC 4: Debate – Is “Big Data” the Future of Comparative-Effectiveness Analysis? Maybe, but Be Afraid, Be Very Afraid! Robert A. Harrington
3:50 PM Roundtable Discussion With Audience Q&A
Session II. Clinical Trial Analysis: Critical Issues, Part 2 4:00 PM - 6:00 PM Moderators: Ajay J. Kirtane, Roxana Mehran Discussants: Donald Cutlip, Darrel P. Francis, Hector M. Garcia-Garcia, Robert A. Harrington, Francesco Pelliccia, William S. Weintraub, Robert W. Yeh
4:00 PM HOT TOPIC 5: Debate – Patient-Centered/-Reported Outcomes in Device Studies: How Will This Shape the Future of Clinical Studies? Pro – The Patient Matters Most! Suzanne V. Arnold
4:10 PM HOT TOPIC 5: Debate – Patient-Centered/-Reported Outcomes in Device Studies: How Will This Shape the Future of Clinical Studies? Con – Level of Evidence Is Weak! Daniel I. Simon
4:20 PM Roundtable Discussion With Audience Q&A
4:30 PM Keynote Lecture 1: Advantages, Pitfalls, and Analysis Options for Composite Endpoints Stuart J. Pocock
4:45 PM Roundtable Discussion With Audience Q&A
4:55 PM Keynote Lecture 2: The Case for (and the Arguments Against) Moving Quality-of-Life Assessment “Front and Center” in Clinical Trials John A. Spertus
5:10 PM HOT TOPIC 6: Importance of Evaluating Competing and Recurrent Events Within Clinical Trials – Statistical Perspective Eugene H. Blackstone
5:20 PM HOT TOPIC 6: Importance of Evaluating Competing and Recurrent Events Within Clinical Trials – Clinician/Trialist Perspective Robert A. Harrington
5:30 PM Roundtable Discussion With Audience Q&A
5:40 PM Keynote Lecture 3: Single-Center vs Multicenter Trials – Pros, Cons, and Integration Into Evidence Sanjay Kaul
5:50 PM Roundtable Discussion With Audience Q&A The CTO Summit: Conquering the Final Frontier, Part 2 Accreditation: CME/CNE
Monday, October 12 2:00 PM - 6:00 PM Room: Moscone West, 2nd Floor, Room 2020 - 2024
Session IV. Essentials for Problem Solving During Antegrade CTO PCI 2:00 PM - 4:00 PM Moderators: Javier Escaned, William L. Lombardi Discussants: William Nicholson, Ashish Pershad, Barry D. Rutherford, James Sapontis, Makoto Sekiguchi, Elliot J. Smith
2:00 PM Poll 1: What Is the Biggest Challenge in Antegrade CTO PCI? Poll Moderators: Javier Escaned, William L. Lombardi
2:05 PM Problem (and Solution) 1: The Ambiguous or Impenetrable Proximal Cap Ashish Pershad
2:15 PM Problem (and Solution) 2: My Wire Crossed but the Microcatheter Won’t Barry D. Rutherford
2:25 PM Problem (and Solution) 3: My Wire/Device Keeps Going Into a Sidebranch Within the Occlusion William Nicholson
2:35 PM Problem (and Solution) 4: Hematoma Management – How to Avoid and How to Resolve the Difficult Antegrade Case Elliot J. Smith
2:45 PM Roundtable Discussion With Audience Q&A
3:00 PM Poll 2: What Is the Biggest Challenge in Retrograde CTO PCI? Poll Moderators: Javier Escaned, William L. Lombardi
3:05 PM Problem (and Solution) 1: I Wired the Collateral but the Microcatheter Won’t Follow Makoto Sekiguchi
3:15 PM Problem (and Solution) 2: I Can't Complete Reverse CART James Sapontis
3:25 PM Problem (and Solution) 3: Challenges With Wire Externalization Scott Harding
3:35 PM Problem (and Solution) 4: Collateral Perforation Minh Vo 3:45 PM Roundtable Discussion With Audience Q&A
Session V. Complications: Let Me Show You What My Partner Did 4:00 PM - 4:49 PM Moderators: Emmanouil S. Brilakis, Carlo Di Mario Discussants: Yasushi Asakura, Creighton W. Don, Paul Knaapen, Goran K. Olivecrona, Curtiss T. Stinis, Masahisa Yamane
4:00 PM Poll 3: Major Procedural Complications (Death, Major Perforation, Stroke, or Emergent Surgery) of CTO PCI Occur in What Percentage of Patients? Poll Moderators: Emmanouil S. Brilakis, Carlo Di Mario
4:05 PM Complications of CTO PCI: A Review of the Global Registries Curtiss T. Stinis
4:15 PM Coronary Perforation in the Setting of CTO PCI Paul Knaapen
4:23 PM Are Post-CABG CTO Perforations More or Less Worrisome? Creighton W. Don
4:31 PM Roundtable Discussion With Audience Q&A
Session VI. New Directions of CTO PCI 4:49 PM - 6:00 PM Moderator: R. Michael Wyman Discussants: Christopher E. Buller, Mauro Carlino, Tony J. DeMartini, Farouc Jaffer, Sudhir Rathore, Truls Råmunddal, Renato Valenti
4:49 PM OPEN CTO - Procedural and 30-Day Results of Hybrid Strategy for CTO Recanalization James Sapontis
4:59 PM Collagenase and TOSCA-5 Christopher E. Buller
5:09 PM Poll 4: What Would Be the Results of a Large Randomized Trial of CTO PCI vs Medical Therapy? Poll Moderators: Tony J. DeMartini, R. Michael Wyman
5:14 PM SCAAR CTO: Does Treatment Improve Outcomes? Truls Råmunddal
5:24 PM CTO PCI in Patients With ACS and Multivessel Disease Renato Valenti
5:34 PM Can CTO PCI Cure Depression? Farouc Jaffer
5:42 PM Roundtable Discussion With Audience Q&A Interventional Heart Failure Therapies, Part 1 Accreditation: none
Monday, October 12 2:00 PM - 5:50 PM Room: Moscone West, 3rd Floor, Room 3006 - 3008
Session I. Interventional Heart Failure: State of the Art 2:00 PM - 2:45 PM Moderators: Daniel Burkhoff, Ileana L. Pina Discussants: Peter Carson, Graham A. Cassel, Neal L. Eigler, Robert A. Kloner, JoAnn Lindenfeld, Gary L. Schaer
2:00 PM Latest Advances in Medical and Device-Based Therapies for Heart Failure JoAnn Lindenfeld
2:15 PM Heart Failure With Preserved Ejection Fraction: Drugs and Devices Peter Carson
2:30 PM Roundtable Discussion With Audience Q&A
Session II. Percutaneous Valves: Implications for Heart Failure Treatment 2:45 PM - 3:30 PM Moderators: John D. Carroll, Scott Lim Discussants: Steven R. Bailey, Jeroen J. Bax, Adam Groothuis, Alexander Lauten, Helge Möllmann, Alfredo Trento
2:45 PM Is TAVR a Therapy for CHF Patients With Severe AS? Jeroen J. Bax
2:55 PM Is Percutaneous Mitral Valve Replacement or Annuloplasty a Therapy for CHF Patients With Severe MR? John D. Carroll
3:05 PM Is Percutaneous Tricuspid Valve Annuloplasty a Therapy for CHF Patients With Severe TR? Adam Groothuis
3:15 PM Roundtable Discussion With Audience Q&A
Session III. Ventricular Remodeling Devices for Heart Failure 3:30 PM - 4:20 PM Moderators: Ileana L. Pina, James E. Udelson Discussants: William T. Abraham, Jeffrey S. Borer, Marco A. Costa, Joost Daemen, Alexandra J. Lansky, Petr Neuzil
3:30 PM Overview of Ventricular Remodeling Ileana L. Pina
3:35 PM Parachute Device: Description and Clinical Update William T. Abraham
3:45 PM BioVentrix: Description and Clinical Update Petr Neuzil
3:55 PM LoneStar Heart: Description and Clinical Update Joost Daemen
4:05 PM Roundtable Discussion With Audience Q&A
Session IV. Pressure Monitoring for Reducing Hospitalizations and Improving Quality of Life 4:20 PM - 5:15 PM Moderators: Jeffrey S. Borer, Neal L. Eigler Discussants: Roni Abbo, William T. Abraham, Frederick Kushner, JoAnn Lindenfeld
4:20 PM Next-Generation Sensors and Vision for the Future of Home Monitoring William T. Abraham
4:35 PM Latest Data on CardioMEMS William T. Abraham
4:45 PM Noninvasive Fluid Status Monitoring Roni Abbo
4:55 PM Roundtable Discussion With Audience Q&A
Session V. Interatrial Shunts for Heart Failure 5:15 PM - 5:50 PM Moderators: William T. Abraham, David W.M. Muller Joost Daemen Discussants: Mark Goldberger, Ileana L. Pina, Josep Rodés-Cabau, Joachim Schofer, Sanjiv Shah
5:15 PM Interatrial Shunt for HFrEF and HFpEF (V-Wave) Josep Rodés-Cabau
5:25 PM Interatrial Shunt for HFpEF (DC Devices) Sanjiv Shah
5:35 PM Roundtable Discussion With Audience Q&A Left Atrial Appendage Closure: Indications, Technique, and Outcomes, Part 2 Accreditation: CME/CNE
Monday, October 12 2:00 PM - 6:00 PM Room: Moscone West, 3rd Floor, Room 3002 - 3004
Session I. Technique of LAA Closure, Part 2 2:00 PM - 3:57 PM Moderators: Maurice Buchbinder, Brian K. Whisenant Discussants: Krzysztof Bartus, Sameer Gafoor, Reda Ibrahim, Jan Kovac, Mark Reisman, Josep Rodés- Cabau, Jacqueline Saw, Steven J. Yakubov
2:00 PM Watchman Step-by-Step Mark Reisman
2:15 PM Roundtable Discussion With Audience Q&A
2:20 PM Amplatzer Cardiac Plug (ACP) Step-by-Step Reda Ibrahim
2:35 PM Roundtable Discussion With Audience Q&A
2:40 PM Transpericardial LAA Closure With Lariat Step-by-Step Steven J. Yakubov
2:55 PM Roundtable Discussion With Audience Q&A
3:00 PM Anticoagulation in the Periimplant Period (Pre, Peri, and Post): An Evidence-Based Analysis Sameer Gafoor
3:12 PM Roundtable Discussion With Audience Q&A
3:17 PM A Challenging LAA Closure Case Case Presenter: Jacqueline Saw
3:32 PM Pre-debate Vote: Is Pericardial LAA Exclusion Better Than Endocardial LAA Closure? Poll Moderators: Maurice Buchbinder, Brian K. Whisenant
3:34 PM Debate: Is Pericardial LAA Exclusion Better Than Endocardial LAA Closure? Yes, Avoiding an Intracardiac Implant Is Safer and More Effective! Krzysztof Bartus
3:42 PM Debate: Is Pericardial LAA Exclusion Better Than Endocardial LAA Closure? No, Intracardiac LAA Closure Is Proven, and the Pericardial Approach Has Major Concerns! Josep Rodés-Cabau
3:50 PM Post-debate Vote (Who Won?): Is Pericardial LAA Exclusion Better Than Endocardial LAA Closure? Poll Moderators: Maurice Buchbinder, Brian K. Whisenant
3:52 PM Roundtable Discussion With Audience Q&A
Session II. New Devices and Future Directions 3:57 PM - 6:00 PM Moderators: Brij Maini, Horst Sievert Discussants: Sameer Gafoor, Reda Ibrahim, Yat-Yin Lam, Peter B Sick, Eleftherios Sideris, Brian K. Whisenant
3:57 PM Coherex WaveCrest and the WAVECREST 2 Randomized Trial Brian K. Whisenant
4:09 PM Roundtable Discussion With Audience Q&A
4:12 PM Liftech LAA Occluder Yat-Yin Lam
4:22 PM Roundtable Discussion With Audience Q&A
4:24 PM Amulet Reda Ibrahim
4:34 PM Roundtable Discussion With Audience Q&A
4:36 PM Watchman Generation 5 (Watchman Flex) Horst Sievert
4:46 PM Roundtable Discussion With Audience Q&A
4:48 PM Occlutech LAA Occluder Sameer Gafoor
4:58 PM Roundtable Discussion With Audience Q&A
5:00 PM AEGIS Krzysztof Bartus
5:10 PM Roundtable Discussion With Audience Q&A
5:12 PM Cardia UltraSept Reda Ibrahim
5:22 PM Roundtable Discussion With Audience Q&A
5:24 PM PROLIPSIS Eleftherios Sideris
5:34 PM Roundtable Discussion With Audience Q&A
5:36 PM Clinical Design of ASAP-2 Maurice Buchbinder 5:46 PM Roundtable Discussion With Audience Q&A
Metallic Drug-Eluting Stents: Tomorrow’s Technology Accreditation: CME/CNE
Monday, October 12 2:00 PM - 6:10 PM Room: Moscone West, 3rd Floor, Room 3001 - 3005
Session I. Improving Upon Today’s Durable-Polymer DES 2:00 PM - 2:51 PM Moderators: Fernando Alfonso, Juan F. Granada Discussants: Rafael Beyar, Aloke V. Finn, Michael Joner, Detlef G. Mathey, Manuel Pan, Lorenz Raber
2:00 PM Pre-debate Vote: Should Precious R&D Resources Be Spent on Further Improving Stent and Delivery System Design and Developing New Durable Polymers? Poll Moderators: Fernando Alfonso, Juan F. Granada
2:02 PM Debate: Can Today’s Metallic Stent Platforms, Delivery Systems, and Durable Polymers Be Meaningfully Improved? Yes, Made Thinner and More Flexible, With Optimally Designed Platforms and Enhanced Polymers – There Is Still Room for Improvement! Elazer R. Edelman
2:09 PM Debate: Can Today’s Metallic Stent Platforms, Delivery Systems, and Durable Polymers Be Meaningfully Improved? No, the Bench, Experimental, and Clinical Results Are So Good, We Probably Have Reached a Therapeutic Plateau! Lisette Okkels Jensen
2:16 PM Roundtable Discussion With Audience Q&A
2:21 PM Post-debate Vote (Who Won?): Should Precious R&D Resources Be Spent on Further Improving Stent and Delivery System Design and Developing New Durable Polymers? Poll Moderators: Fernando Alfonso, Juan F. Granada
2:23 PM Microengineered Grooved Stent Surfaces and Beyond: Technology Description and Preliminary Data Juan F. Granada
2:30 PM A New Durable-Polymer–Based Cobalt Chromium Stent: Rationale for and Design Characteristics of the BioNIR Stent and Clinical Development Program Pieter C. Smits
2:37 PM Stentys Self-Expanding Stent With a Durable Polymer Eluting Sirolimus: Extended 2- Year Clinical and OCT Results From APPOSITION IV Robert-Jan van Geuns
2:44 PM Roundtable Discussion With Audience Q&A Session II. DES With Bioabsorbable Polymers 2:51 PM - 4:23 PM Moderators: Pieter C. Smits, Philip M. Urban Discussants: Tim A. Fischell, Elvin Kedhi, Karel T. Koch, Marco A. Perin, Ashok Seth, Clemens von Birgelen
2:51 PM Why Contemporary Durable Polymers Are Not Good Enough. Do Any of the Current Bioabsorbable Polymers Make the Grade? Renu Virmani
2:58 PM Device and Clinical Program Highlights: Firehawk Bo Xu
3:05 PM Device and Clinical Program Highlights: Micell Alexandra J. Lansky
3:12 PM Device and Clinical Program Highlights: BioMime Roberto Botelho
3:19 PM Device and Clinical Program Highlights: OrbusNeich Combo Roxana Mehran
3:26 PM Device and Clinical Program Highlights: DESyne BD
3:33 PM Device and Clinical Program Highlights: Abluminus Sameer I. Dani
3:40 PM Device and Clinical Program Highlights: SinoMed BuMA Run-Lin Gao
3:47 PM Device and Clinical Program Highlights: Inspiron Pedro A. Lemos
3:54 PM Device and Clinical Program Highlights: Orsiro Thomas Pilgrim
4:01 PM Device and Clinical Program Highlights: Alex Dariusz Dudek
4:08 PM Roundtable Discussion With Audience Q&A
Session III. Polymer-Free Drug-Coated Stents 4:23 PM - 5:03 PM Moderators: Marie-Claude Morice, Leif Thuesen Discussants: Robert A. Byrne, Didier Carrié, David W.M. Muller, Andrzej J. Ochala, Christian M. Spaulding, Yasunori Ueda
4:23 PM BioFreedom I: Angiographic Results and Late Clinical Outcomes of the FIM Trial Christian M. Spaulding 4:30 PM BioFreedom II: LEADERS FREE Rationale and Late-Breaking Clinical Trial Preview Philip M. Urban
4:37 PM Drug-Filled Stent: Concept, Preclinical Studies, and Early Clinical Observations Stephen G. Worthley
4:45 PM Cre8: Design, Current Status, and Future Directions Didier Carrié
4:53 PM Roundtable Discussion With Audience Q&A
Session IV. Dedicated Systems for Specific Lesion Subsets: A Case-Based Approach 5:03 PM - 6:10 PM Moderators: Martin B. Leon, Pieter C. Smits Discussants: Yaron Almagor, Shao-Liang Chen, Karel T. Koch, Michael J. Rinaldi, Goran Stankovic, Stephen G. Worthley
5:03 PM Case 1: Bifurcations or Left Main - The Axxess Stent Christophe Dubois
5:10 PM Case 2: Bifurcations or Left Main - The BiOSS Stent Robert J. Gil
5:17 PM Case 3: Bifurcations or Left Main - The Nile Stent Ivo Petrov
5:24 PM Case 4:Bifurcations or Left Main - The Stentys Stent Carlo Briguori
5:31 PM Case 5: Bifurcations or Left Main - The Tryton Stent Robert-Jan van Geuns
5:39 PM Case 6: Acute Myocardial Infarction or Thrombus Containing Lesions - The MGuard Prime Stent Chaim S. Lotan
5:46 PM Case 7: Very Long Lesions in Tapering Vessels - The BioMime Morph Stent Teguh Santoso
5:53 PM Case 8: Small Vessels - The Svelte Stent Pieter R. Stella
6:00 PM Roundtable Discussion With Audience Q&A
Optimizing Outcomes With Physiologic Lesion Assessment Accreditation: CME/CNE
Monday, October 12 2:00 PM - 6:00 PM Room: Moscone West, 2nd Floor, Room 2001 - 2005
Session I. The “New” Nuances of Coronary Physiology 2:00 PM - 3:00 PM Moderators: Justin E. Davies, Bernard De Bruyne Discussants: Michael J. Lim, Hitoshi Matsuo, Arnold Seto, Maria Siebes, Pim A.L. Tonino, Gerald S. Werner
2:00 PM Adenosine Variability and Other FFR Artifacts Morton J. Kern
2:12 PM CFR/FFR/IMR/HMR Discordance: Understanding the Differences Jan J. Piek
2:24 PM Nonhyperemic Indices of Stenosis Severity: Ready for Prime Time? Allen Jeremias
2:36 PM The Ischemic Continuum: What Is the Significance of a Lower FFR? Nils Johnson
2:48 PM Roundtable Discussion With Audience Q&A
Session II. Coronary Physiology in Critical Clinical Subsets 3:00 PM - 4:00 PM Moderators: Allen Jeremias, Nils Johnson Discussants: Robert T Gerber, Amir Lerman, Jan J. Piek, Bruce Samuels, Sayan Sen, Nobuhiro Tanaka
3:00 PM Fifteen-Year DEFER and 5-Year FAME Outcomes Nico H.J. Pijls
3:12 PM Intracoronary Physiology in NSTEMI and STEMI: Is Accurate Lesion Assessment Possible? Colin Berry
3:24 PM Left Main Disease: When to Use FFR vs IVUS William F. Fearon
3:36 PM Novel Hyperemic Agents (Regadenoson, Nicorandil, and Nitroprusside) Habib Samady
3:48 PM Roundtable Discussion With Audience Q&A
Session III. Coronary Physiology Conundrums 4:00 PM - 5:00 PM Moderators: Sergio B Baptista, Eric Van Belle Discussants: Adriano Caixeta, Massoud A. Leesar, Giampaolo Niccoli, Ricardo Petraco, Nico H.J. Pijls, Tim P. van de Hoef 4:00 PM Physiological Assessment in Multivessel Disease: What Will SYNTAX 2 and FAME 3 Tell Us? Bernard De Bruyne
4:12 PM Should Every Referral for CABG Be Proceeded by Physiological Assessment? Erick Schampaert
4:24 PM When and How to Assess the Microvasculature: A Practical Guide Javier Escaned
4:36 PM Advanced iFR: Lesion Assessment Using iFR/FFR Pullback Justin E. Davies
4:48 PM Roundtable Discussion With Audience Q&A
Session IV. Changing Daily Practice: Physiology in the Trenches 5:00 PM - 6:00 PM Moderators: Daniel S. Berman, Pamela S. Douglas Discussants: Ravinay Bhindi, James K. Min, Luis Raposo, Arnold Seto, Murat Sezer, Niels van Royen
5:00 PM FFR-CT (Pre-PLATFORM data): A Paradigm Change? James K. Min
5:12 PM FFR-CT: PLATFORM Results Pamela S. Douglas
5:24 PM FFR and Changing Ad Hoc Cath Lab Decisions Michael J. Lim
5:36 PM Overcoming Barriers to Coronary Physiology Adoption in Everyday Practice Manesh R. Patel
5:48 PM Roundtable Discussion With Audience Q&A
PCI Pharmacotherapy: Procedural Antithrombins and Dual Antiplatelet Therapy Accreditation: CME/CNE
Monday, October 12 2:00 PM - 6:00 PM Room: Moscone West, 2nd Floor, Room 2014 - 2018
Session I. Antithrombins for PCI in ACS and Stable CAD 2:00 PM - 3:29 PM Moderators: John A. Bittl, Robert A. Harrington Discussants: Laurent Bonello, Harold L. Dauerman, Bill J. French, Yaling Han, Jorge F. Saucedo, Rod H. Stables
2:00 PM Bivalirudin vs Heparin in ACS: The New Data – MATRIX Antithrombin Results Marco Valgimigli
2:10 PM Bivalirudin Pearls: Necessity With Radial Access, Infusion Dose and Duration, Use in CKD, and More Philippe Gabriel Steg
2:18 PM What, if Any, Is the Role for LMWH and GP IIb/IIIa Inhibitors in ACS or During PCI? Jorge F. Saucedo
2:26 PM Cangrelor + Bivalirudin: The Perfect Marriage or a Forced Union? Harvey D. White
2:34 PM Procedural Anticoagulants in Sweden: Results From the SCAAR Registry and Rationale for VALIDATE-SWEDEHEART David Erlinge
2:42 PM Is Prolonged Antithrombin Use After Primary PCI in STEMI Beneficial? Mahesh Madhavan
2:50 PM Roundtable Discussion With Audience Q&A
3:05 PM Pre-debate Vote: What Procedural Anticoagulant Should Be Used in Stable CAD? Poll Moderators: John A. Bittl, Robert A. Harrington
3:07 PM Debate: Bivalirudin vs Heparin During PCI in Stable CAD? Bivalirudin! George D. Dangas
3:14 PM Debate: Bivalirudin vs Heparin During PCI in Stable CAD? Unfractionated Heparin! Michael S. Lee
3:21 PM Roundtable Discussion With Audience Q&A
3:27 PM Post-debate Vote (Who Won?): What Procedural Anticoagulant Should Be Used in Stable CAD? Poll Moderators: John A. Bittl, Robert A. Harrington
Session II. Antiplatelet Agent Preloading Before and During PCI 3:29 PM - 4:08 PM Moderators: Eric Boersma, E. Magnus Ohman Discussants: Theodore A. Bass, Dmitriy N. Feldman, Fausto Feres, Hitinder S. Gurm, Duk-Woo Park
3:29 PM New Data: Results of the HEAT-PPCI Platelet Substudies Rod H. Stables
3:37 PM Pre-debate Vote: What Is the Optimal ADP-Antagonist Preloading Approach in STEMI? Poll Moderators: Eric Boersma, E. Magnus Ohman 3:39 PM Debate: What Is the Optimal ADP-Antagonist Preloading Approach in STEMI? Prehospital or Crushed Ticagrelor! Dimitrios Alexopoulos
3:46 PM Debate: What Is the Optimal ADP-Antagonist Preloading Approach in STEMI? Prasugrel Is Just as Good! Giuseppe Biondi-Zoccai
3:53 PM Debate: What Is the Optimal ADP-Antagonist Preloading Approach in STEMI? Cangrelor! Deepak L. Bhatt
4:00 PM Roundtable Discussion With Audience Q&A
4:06 PM Post-debate Vote (Who Won?): What Is the Optimal ADP-Antagonist Preloading Approach in STEMI? Poll Moderators: Eric Boersma, E. Magnus Ohman
Session III. DAPT Duration After DES 4:08 PM - 5:20 PM Moderators: John A. Bittl, Gary L. Schaer Discussants: Usman Baber, Hyeon-Cheol Gwon, Gérard Helft, David F. Kong, Laura Mauri, Srihari S. Naidu
4:08 PM Pre-debate Vote: What Is the Optimal Duration of DAPT After DES? Poll Moderators: John A. Bittl, Gary L. Schaer
4:10 PM Debate: The Optimal Duration of DAPT After DES Is More Than 12 Months for Most! Laura Mauri
4:17 PM Debate: The Optimal Duration of DAPT After DES Is Less Than 12 Months for Most! Tullio Palmerini
4:24 PM Does PEGASUS Inform the Debate? Stephen D. Wiviott
4:31 PM Roundtable Discussion With Audience Q&A
4:38 PM Post-debate Vote (Who Won?): What Is the Optimal Duration of DAPT After DES? Poll Moderators: John A. Bittl, Gary L. Schaer
4:40 PM Risk vs Benefit: Can We Determine Which Patients Should Be Treated With Long-term DAPT? Matthew T. Roe
4:48 PM Is Dropping Aspirin the Magic Solution? Pascal Vranckx
4:56 PM Roundtable Discussion With Audience Q&A
5:01 PM DAPT Duration Case 1: An Elderly Patient With CKD and Left Main Bifurcation Stenting – In-Hospital Course Gennaro Giustino
5:05 PM Audience Vote Case 1: Planned DAPT Duration Strategy Poll Moderators: John A. Bittl, Gary L. Schaer
5:07 PM Panel Discussion Case 1: Planned DAPT Duration Strategy
5:11 PM DAPT Duration Case 2: An Elderly Patient With CKD and Left Main Bifurcation Stenting – Postdischarge Course Gennaro Giustino
5:14 PM Audience Vote Case 2: Planned DAPT Strategy Poll Moderators: John A. Bittl, Gary L. Schaer
5:16 PM Panel Discussion Case 2: Planned DAPT Strategy
Session IV. Challenging Cases and Difficult Antiplatelet/Antithrombin Decisions 5:20 PM - 6:00 PM Moderators: Paul A. Gurbel, Daniel I. Simon Discussants: David Antoniucci, Sorin J. Brener, Michalis Hamilos, Duane S. Pinto, Ivan C. Rokos, Marco V. Wainstein
5:20 PM Case 1: Active Bleeding Soon After DES Implantation Usman Baber
5:23 PM Audience Vote Case 1: How to Manage This Patient Poll Moderators: Paul A. Gurbel, Daniel I. Simon
5:25 PM Roundtable Discussion With Audience Q&A
5:30 PM Case 1: How Did We Manage This Patient? Usman Baber
5:33 PM Case 2: A Patient With Cardiac Arrest and ST-Segment Elevation Michael S. Lee
5:36 PM Audience Vote Case 2: How to Manage This Patient Poll Moderators: Paul A. Gurbel, Daniel I. Simon
5:38 PM Roundtable Discussion With Audience Q&A
5:43 PM Case 2: How Did We Manage This Patient? Michael S. Lee
5:46 PM Case 3: Hot ACS and a History of Possible Aspirin Anaphylaxis Thomas D. Stuckey
5:49 PM Audience Vote Case 3: How to Manage This Patient Poll Moderators: Paul A. Gurbel, Daniel I. Simon 5:51 PM Roundtable Discussion With Audience Q&A
5:56 PM How Did We Manage This Patient? Thomas D. Stuckey
Peripheral Drug-Coated Balloons Accreditation: CME/CNE
Monday, October 12 2:00 PM - 6:00 PM Room: Moscone West, 2nd Floor, Room 2006 - 2008
Session I. Basics of DCB Concepts 2:00 PM - 2:36 PM Moderators: Greg L. Kaluza, Thomas Zeller Discussants: George L Adams, Eric J. Dippel, Gunnar Tepe, Jochen Wöhrle
2:00 PM Technical Overview of FDA-Approved and CE-Marked DCB Technologies for PVD Intervention Greg L. Kaluza
2:10 PM FIH Data Review Regarding Degree and Duration of DCB Efficacy in De Novo Lesions: Is There a Class Effect? Gunnar Tepe
2:18 PM Optimizing Outcomes With DCB: Tips and Tricks Thomas Zeller
2:26 PM Roundtable Discussion With Audience Q&A
Session II. Randomized Controlled Trials of Peripheral DCBs 2:36 PM - 3:14 PM Moderators: William A. Gray, Peter A. Schneider Discussants: John R. Laird Jr, Mahmood K. Razavi, Bruno Scheller, Andrej Schmidt
2:36 PM IN.PACT SFA 1-year Outcomes: Subgroup Analyses John R. Laird Jr
2:46 PM Extended Follow-up From LEVANT 2: Two-Year Follow-up and Subgroup Analyses Andrej Schmidt
2:56 PM The ILLUMINATE RCT: One-Year Outcomes Mahmood K. Razavi
3:04 PM Roundtable Discussion With Audience Q&A Session III. Peripheral DCB Use in the Real World 3:14 PM - 3:56 PM Moderators: John R. Laird Jr, Gunnar Tepe Discussants: Gary M. Ansel, Gary Gershony, Christopher D. Owens, Michael H. Wholey, Thomas Zeller
3:14 PM DCB Treatment of In-Stent Restenosis With or Without Upfront Debulking: Updated Results Thomas Zeller
3:22 PM DCB for Long and Highly Calcified Vessels: Is Upfront Vessel Preparation a Rational Choice? Gunnar Tepe
3:30 PM The IN.PACT Global Registry: One-Year Outcomes Using the IN.PACT DCB in an Unrestricted, Real-World Environment Gary M. Ansel
3:38 PM 12 Month Outcomes From the Lutonix Global SFA Real-World Registry Marcus Thieme
3:46 PM Roundtable Discussion With Audience Q&A
Session IV. Peripheral DCBs and the Use of Ancillary Devices 3:56 PM - 5:02 PM Moderators: Krishna J. Rocha-Singh, Andrej Schmidt Discussants: Roger Gammon, Lawrence A. Garcia, Aljoscha Rastan, Peter A. Schneider, Gunnar Tepe
3:56 PM Next-Generation DCBs: Alternative Coatings and Drug-Delivery Platforms for SFA Intervention Juan F. Granada
4:04 PM DCBs Plus Adjunctive BMS Use: Current Use, Rationale, and Pitfalls Andrej Schmidt
4:12 PM Roundtable Discussion With Audience Q&A
4:20 PM “Spot” Stenting and DCB Use: Rationale and Therapeutic Options Peter A. Schneider
4:28 PM DCB With or Without Atherectomy in CFA Lesions vs Surgery: Rationale and Design of the PESTO-CFA Trial Aljoscha Rastan
4:36 PM Unmet Technical Needs and Opportunities for Development of Next-Generation Technologies Lawrence A. Garcia
4:44 PM Restenosis Patterns After DCB and Management Strategies Gunnar Tepe 4:52 PM Roundtable Discussion With Audience Q&A
Session V. Below-the-Knee DCB Indications 5:02 PM - 6:00 PM Moderators: Gary M. Ansel, J. A. Mustapha Discussants: R. Stefan Kiesz, Francesco Liistro, Gregory Mishkel, Peter A. Schneider, Ron Waksman
5:02 PM BTK Disease: Impact of Disease Complexity on Technical Approach and Clinical Outcomes – Are DCBs the Right Answer? Peter A. Schneider
5:10 PM DCB in BTK Intervention: Summary of the Evidence From 2 Failed RCTs – IN.PACT DEEP and BIOLUX P-II J. A. Mustapha
5:18 PM After 2 Failed RCTs: Root-Cause Analysis, Unmet Technical Needs and Opportunities for the Development of Next-Generation DCBs, and Studies J. A. Mustapha
5:26 PM Roundtable Discussion With Audience Q&A
5:34 PM Pre-debate Vote: Do DCBs Work Now for the BTK Indication? Will They Ever Work for BTK? Poll Moderator: Gary M. Ansel
5:36 PM Clinical Trial Debate: Do DCBs Work for the BTK Indication? Yes, Perform DCB Angioplasty of BTK Lesions Correctly and They Work! Francesco Liistro
5:44 PM Clinical Trial Debate: Do DCBs Work for the BTK Indication? No, DCBs Will Never Work in BTK Arteries! Ron Waksman
5:52 PM Post-debate Vote (Who Won?): Do DCBs Work Now for the BTK Indication? Will They Ever Work for BTK? Poll Moderators: Gary M. Ansel, J. A. Mustapha
5:54 PM Roundtable Discussion With Audience Q&A
Transcatheter Aortic Valve Therapies: Today and Tomorrow, Part 2 Accreditation: CME/CNE
Monday, October 12 2:00 PM - 6:10 PM Room: Moscone West, 3rd Floor, Room 3007 - 3011
Session IV. TAVR Complex Case Management, Part 1 2:00 PM - 3:24 PM Moderators: Robert O. Bonow, Allan Schwartz Discussants: Marco Barbanti, G. Michael Deeb, David Hildick-Smith, Anna Sonia Petronio, Simon Redwood, Molly Szerlip, Vinod H. Thourani, Nicolas M. Van Mieghem, Mathew Williams
2:00 PM Severe LV Dysfunction and TAVR: Case Presentation Case Presenter: Kendra J. Grubb
2:05 PM Severe LV Dysfunction and TAVR: Thoughtful Commentary on the Case G. Michael Deeb
2:10 PM Roundtable Discussion With Audience Q&A
2:12 PM Bicuspid Aortic Valve Disease and TAVR: Case Presentation Case Presenter: Colin M. Barker
2:17 PM Bicuspid Aortic Valve Disease and TAVR: Thoughtful Commentary on the Case Mathew Williams
2:22 PM Roundtable Discussion With Audience Q&A
2:24 PM Moderate Aortic Stenosis With CHF: Case Presentation Case Presenter: Hemal Gada
2:29 PM Moderate Aortic Stenosis With CHF: Thoughtful Commentary on the Case (UNLOAD Trial) Nicolas M. Van Mieghem
2:34 PM Roundtable Discussion With Audience Q&A
2:36 PM Aortic Stenosis With Simple and Complex CAD: Case Presentation Case Presenter: Jean-Michel Paradis
2:41 PM Aortic Stenosis With Simple and Complex CAD: Thoughtful Commentary on the Case (ACTIVATION Trial) Simon Redwood
2:46 PM Roundtable Discussion With Audience Q&A
2:48 PM Aortic Stenosis and Mitral Regurgitation: Case Presentation Case Presenter: Alan Zajarias
2:53 PM Aortic Stenosis and Mitral Regurgitation: Thoughtful Commentary on the Case (and MitraClip Considerations) Marco Barbanti
2:58 PM Roundtable Discussion With Audience Q&A
3:00 PM Aortic Stenosis With Severe COPD: Case Presentation Case Presenter: Kishore J. Harjai
3:05 PM Aortic Stenosis With Severe COPD: Thoughtful Commentary on the Case Vinod H. Thourani 3:10 PM Roundtable Discussion With Audience Q&A
3:12 PM Severe Asymptomatic Aortic Stenosis: Case Presentation Case Presenter: Haim Danenberg
3:17 PM Severe Asymptomatic Aortic Stenosis: Thoughtful Commentary on the Case Allan Schwartz
3:22 PM Roundtable Discussion With Audience Q&A
Session V. TAVR Complex Case Management, Part 2 3:24 PM - 4:48 PM Moderators: Howard C. Herrmann, Patrick T. O'Gara Discussants: Vinayak Bapat, Charles J. Davidson, Robert A. Guyton, James B. Hermiller Jr, Neal S. Kleiman, Jeffrey J. Popma, Michael J. Reardon, Olaf Wendler
3:24 PM Severe LVOT Calcification and TAVR: Case Presentation Case Presenter: Augusto D. Pichard
3:29 PM Severe LVOT Calcification and TAVR: Thoughtful Commentary on the Case Neal S. Kleiman
3:34 PM Roundtable Discussion With Audience Q&A
3:36 PM Severe Frailty With Aortic Stenosis and TAVR: Case Presentation Case Presenter: Sandra Lauck
3:41 PM Severe Frailty With Aortic Stenosis and TAVR: Thoughtful Commentary on the Case Jeffrey J. Popma
3:46 PM Roundtable Discussion With Audience Q&A
3:48 PM Severe Renal Disease and TAVR: Case Presentation Case Presenter: S. Chiu Wong
3:53 PM Severe Renal Disease and TAVR: Thoughtful Commentary on the Case Charles J. Davidson
3:58 PM Roundtable Discussion With Audience Q&A
4:00 PM Aortic Stenosis With Extreme Comorbidities (the Futile Patient): Case Presentation Case Presenter: Neal S. Kleiman
4:05 PM Aortic Stenosis With Extreme Comorbidities (the Futile Patient): Thoughtful Commentary on the Case Robert A. Guyton
4:10 PM Roundtable Discussion With Audience Q&A
4:12 PM Bioprosthetic Aortic Valve Failure and TAVR: Case Presentation Case Presenter: Stephen R. Ramee 4:17 PM Bioprosthetic Aortic Valve Failure and TAVR: Thoughtful Commentary on the Case Vinayak Bapat
4:22 PM Roundtable Discussion With Audience Q&A
4:24 PM Poor Femoral Access and TAVR (Alternative Access): Case Presentation Case Presenter: Richard Smalling
4:29 PM Poor Femoral Access and TAVR (Alternative Access): Thoughtful Commentary on the Case Michael J. Reardon
4:34 PM Roundtable Discussion With Audience Q&A
4:36 PM Low Flow: Low-Gradient Aortic Stenosis and TAVR – Case Presentation Case Presenter: Chet Rihal
4:41 PM Low Flow: Low-Gradient Aortic Stenosis and TAVR – Thoughtful Commentary on the Case Howard C. Herrmann
4:46 PM Roundtable Discussion With Audience Q&A
Session VI. TAVR Complex Case Management, Part 3 4:48 PM - 6:10 PM Moderators: D. Craig Miller, Alec S. Vahanian Discussants: Vasilis Babaliaros, Vinayak Bapat, Stephen J.D. Brecker, Kendra J. Grubb, Samir R. Kapadia, Dean J. Kereiakes, Jan Kovac, Allan Schwartz, Hendrik Treede, Steven J. Yakubov
4:48 PM High Risk for Coronary Occlusion and TAVR: Case Presentation Case Presenter: David A. Wood
4:53 PM High Risk for Coronary Occlusion and TAVR: Thoughtful Commentary on the Case James B. Hermiller Jr
4:58 PM Roundtable Discussion With Audience Q&A
5:00 PM Extreme Horizontal Aorta and TAVR: Case Presentation Case Presenter: Steven J. Yakubov
5:05 PM Extreme Horizontal Aorta and TAVR: Thoughtful Commentary on the Case Vasilis Babaliaros
5:10 PM Roundtable Discussion With Audience Q&A
5:12 PM Mild-to-Moderate Paravalvular Aortic Regurgitation After TAVR: Case Presentation Case Presenter: Anita Asgar
5:17 PM Mild-to-Moderate Paravalvular Aortic Regurgitation After TAVR: Thoughtful Commentary on the Case Samir R. Kapadia 5:22 PM Roundtable Discussion With Audience Q&A
5:24 PM Small Aortic Annulus/Valve (Native or Bioprosthetic) and TAVR: Case Presentation Case Presenter: Stephen J.D. Brecker
5:29 PM Small Aortic Annulus/Valve (Native or Bioprosthetic) and TAVR: Thoughtful Commentary on the Case Vinayak Bapat
5:34 PM Roundtable Discussion With Audience Q&A
5:36 PM Predominant or Isolated AR and TAVR: Case Presentation Case Presenter: Stephan Baldus
5:41 PM Predominant or Isolated AR and TAVR: Thoughtful Commentary on the Case Hendrik Treede
5:46 PM Roundtable Discussion With Audience Q&A
5:48 PM Severe Septal Bulge (± Hypertrophic Cardiomyopathy) and TAVR: Case Presentation Case Presenter: Mayra Guerrero
5:53 PM Severe Septal Bulge (± Hypertrophic Cardiomyopathy) and TAVR: Thoughtful Commentary on the Case Jan Kovac
5:58 PM Roundtable Discussion With Audience Q&A
6:00 PM Special Lecture: Systematic Review on Management Strategies for Asymptomatic Severe AS Philippe Généreux
Transcatheter Mitral Valve Therapies: Today and Tomorrow, Part 2 Accreditation: CNE/CME
Monday, October 12 2:00 PM - 6:10 PM Room: Moscone West, 3rd Floor, Room 3014 - 3018
Session I. Transcatheter Mitral Valve Replacement: Overarching Concepts and Emerging Insights 2:00 PM - 3:09 PM Moderators: Michael J. Mack, Francesco Maisano Discussants: Vinayak Bapat, Danny Dvir, Mayra Guerrero, Jonathon A. Leipsic, Patrick M. McCarthy, Nicolo Piazza, Paul Sorajja, John G. Webb
2:00 PM For Years We’ve Been Hearing Surgical MV Repair Is Always Preferable to Replacement – So, Why Transcatheter MV Replacement?! John G. Webb 2:06 PM Is Hemodynamic Collapse Due to Increased Afterload After MV Replacement in Severe MR With Reduced LVEF a Real Phenomenon? Patrick M. McCarthy
2:12 PM Access Site Alternatives for Transcatheter MV Replacement: Transatrial, Transapical, or Transeptal? Nicolo Piazza
2:19 PM Failure Modes for Transcatheter MV Replacement and Their Implications: Paravalvular Leaks, LVOT, Embolization, and More Paul Sorajja
2:27 PM CT Imaging to Guide Selection and Treatment for Transcatheter MV Replacement Jonathon A. Leipsic
2:33 PM Preoperative Planning for Mitral Valve-in-Valve/Ring Procedures: Integrating Imaging and the Mitral App Vinayak Bapat
2:39 PM Transcatheter Valve Replacement for Mitral Bioprosthetic Valve and Ring Annuloplasty Failures: Multicenter VIVID Registry Results Danny Dvir
2:47 PM Transcatheter Valve Replacement for Native Mitral Stenosis: International Registry Results Mayra Guerrero
2:54 PM Roundtable Discussion With Audience Q&A
Session II. Transcatheter Mitral Valve Replacement: Devices and Early Experiences 3:09 PM - 5:10 PM Moderators: David H. Adams, Gregg W. Stone Discussants: Anson Cheung, Juan F. Granada, Francesco Maisano, Ian T. Meredith, Neil E. Moat, Jose Luis Navia, Patrick W. Serruys, Lars Sondergaard, Vinod H. Thourani
3:09 PM CardiAQ: Novel Design Features and Clinical Updates Gian Paolo Ussia
3:20 PM Tendyne: Novel Design Features and Clinical Updates Neil E. Moat
3:31 PM Fortis: Novel Design Features and Clinical Updates Vinod H. Thourani
3:41 PM Tiara: Novel Design Features and Clinical Updates Anson Cheung
3:51 PM Twelve: Novel Design Features and Clinical Updates Ian T. Meredith
4:04 PM SinoMed AccuFit: Novel Design Features and Clinical Updates Patrick W. Serruys
4:12 PM A Novel Transcatheter Mitral Valved Stent for Secondary MR Jose Luis Navia
4:20 PM Valtech Cardiovalve: Novel Design Features and Clinical Updates Francesco Maisano
4:28 PM MValve Docking System: Novel Design Features and Clinical Updates Maurice Buchbinder
4:36 PM Cephea: Novel Design Features and Clinical Updates Juan F. Granada
4:44 PM VALcare: Device Description, Experiences, and Future Directions David Meerkin
4:52 PM Roundtable Discussion With Audience Q&A
Session III. Novel Transcatheter Devices for Mitral Regurgitation 5:10 PM - 6:10 PM Moderators: Jason H. Rogers, John G. Webb Discussants: Sameer Gafoor, James S. Gammie, Jai Raman, Chet Rihal, Joerg Seeburger, Olaf Wendler
5:10 PM NeoChord Update: TACT Results, Lessons Learned, and Next Steps Joerg Seeburger
5:17 PM The Middle Peak Approach: Design, Rationale, and Future Directions Jason H. Rogers
5:24 PM Babic Leaflet Puncture Techniques and Chords: Design and Update Sameer Gafoor
5:31 PM Harpoon Neochords: Design and Update James S. Gammie
5:38 PM Bace External Basal Annuloplasty Device: Design and Update Jai Raman
5:45 PM Cardiac Implants for Mitral (and Tricuspid) Regurgitation: Design and Update Karl-Heinz Kuck
5:52 PM Roundtable Discussion With Audience Q&A
Interventional Innovation, Part 1: Innovative Concepts, Diagnostics, and Therapies I Accreditation: none
Monday, October 12 8:00 AM - 12:00 PM Room: Moscone West, 2nd Floor, Room 2014 - 2018
Session I. Cath Lab Technology Evolution: Robotics, Imaging Integration, and Radiation Reduction 8:00 AM - 10:14 AM Moderators: Charles E. Chambers, Giora Weisz Discussants: Stephen Balter, Theodore A. Bass, Rafael Beyar, Bernard De Bruyne, Neal S. Kleiman, Chad Kliger, Ehtisham Mahmud, James K. Min
8:00 AM Featured Lecture: Integrating Present Technologies Into the Cath Lab of the Future Giora Weisz
8:11 AM Robotically Assisted Vascular Procedures (Corindus) Ehtisham Mahmud
8:19 AM Reduction in Radiation Dose Exposure Using Real-Time Eye Tracking (ControlRad: Tracking Technology) Steven Nichtberger
8:27 AM Roundtable Discussion With Audience Q&A
8:40 AM Image-Based FFR During Coronary Catheterization (Cath-Works) Bernard De Bruyne
8:49 AM Feasibility and Accuracy of FFR Determination by 3D-QCA Johan HC Reiber
8:58 AM A Novel Method for Quantitative Assessment of the Microcirculation by Continuous Saline Infusion Nico H.J. Pijls
9:07 AM Roundtable Discussion With Audience
9:20 AM 3-D Printing for Procedural Planning and Simulation Somjot S. Brar
9:29 AM Real-Time Noninvasive Imaging Guidance for Interventional Procedures James K. Min
9:38 AM Combined Angio-CT as a Novel Imaging Modality for Improved Revascularization of Chronic Total Occlusions Patrick T Siegrist
9:46 AM Optimizing the TAVR Procedure Through Patient-Based Pre-op Simulations (TAVIguide) Matthieu De Beule
9:54 AM 3D Holography for Structural Interventions: The Next Phase Elchanan Bruckheimer 10:02 AM Roundtable Discussion With Audience Q&A
Session II. Large Bore Closure Devices and Percutaneous Aortic Valve Repair Technologies 10:14 AM - 12:00 PM Moderators: Alain G. Cribier, Eberhard Grube Discussants: Robert J. Applegate, Stephen J.D. Brecker, Todd J. Brinton, Philippe Généreux, A. Pieter Kappetein, Michael J. Reardon, Josep Rodés-Cabau
10:14 AM MANTA: First Clinical Experience With the 18-F Vascular Closure System Lawrence A. Garcia
10:24 AM Entourage: Low-Profile Single-Suture TA Closure Device Frank Litvack
10:34 AM SECURE: Thermal-Based Closure System Giora Weisz
10:44 AM InSeal: Intravascular Closure Device
10:54 AM STASIS: Sutureless Transapical Access Technology Hendrik Treede
11:02 AM Roundtable Discussion With Audience Q&A
11:14 AM Percutaneous Aortic Valve Repair Technologies 1: Pi-Cardia Aortic Valve Repair System Michael Jonas
11:22 AM Percutaneous Aortic Valve Repair Technologies 2: CardioSculpt Aortic Valve Scoring System – Technological Concept and FIH Data John G. Webb
11:30 AM Percutaneous Aortic Valve Repair Technologies 3: Aortic Leaflet Restoration Using Balloon-Based Lithoplasty Todd J. Brinton
11:38 AM Percutaneous Aortic Valve Repair Technologies 4: The V8 BAV Technology – Description and Clinical Results Wesley R. Pedersen
11:46 AM Roundtable Discussion With Audience Q&A
Cath Lab Radiation Hazards: Managing Patient, Operator, and Staff Risks, Part 1 Accreditation: CME/CNE
Monday, October 12 1:00 PM - 2:00 PM Room: Moscone North, Lower Level, Room 133 Cath Lab Radiation Hazards: Managing Patient, Operator, and Staff Risks, Part 1 1:00 PM - 2:00 PM Moderators: Stephen Balter, Edwin M. Leidholdt, Jr.
1:00 PM Brief Introduction and Pre-test Stephen Balter, Edwin M. Leidholdt, Jr.
1:10 PM Fundamentals of Radiation Dosing Stephen Balter, Edwin M. Leidholdt, Jr.
1:20 PM Fundamentals of Radiation Biology Stephen Balter, Edwin M. Leidholdt, Jr.
1:30 PM Fluoroscopic Imaging Technology Stephen Balter, Edwin M. Leidholdt, Jr.
1:40 PM Basic Patient Radiation Management (in the Lab) Stephen Balter, Edwin M. Leidholdt, Jr.
1:50 PM Roundtable Discussion With Audience Q&A
Controversies in Interventional Cardiology: The Skeptic’s Corner, Part 1 Accreditation: CME/CNE
Monday, October 12 1:00 PM - 2:00 PM Room: Moscone South, Lower Level, Room 102
Primary PCI Issues: We’re Skeptical! 1:00 PM - 2:00 PM Moderators: Nick Curzen, Ajay J. Kirtane Discussants: Davide Capodanno, David J. Cohen, David P. Faxon, Anthony H. Gershlick, Cindy L. Grines, Shamir R. Mehta
1:00 PM I Don’t Believe Bivalirudin Should Routinely Be Used as the First-line Anticoagulant in Primary PCI! David J. Cohen
1:10 PM Roundtable Discussion With Audience Q&A
1:20 PM I Don’t Believe Radial Artery Access Should Routinely Be Used in Primary PCI! Cindy L. Grines
1:30 PM Roundtable Discussion With Audience Q&A
1:40 PM I Don’t Believe Multivessel Revascularization Should Routinely Be Performed During the Index Primary PCI or Before Hospital Discharge! Shamir R. Mehta
1:50 PM Roundtable Discussion With Audience Q&A
Echo Guidance of Interventional Procedures: An ASE-Sponsored Symposium Accreditation: CME/CNE
Monday, October 12 1:00 PM - 2:00 PM Room: Moscone North, Lower Level, Room 131
Echo Guidance of Interventional Procedures: An ASE-Sponsored Symposium 1:00 PM - 2:00 PM Moderators: Paul A. Grayburn, Neil J. Weissman Discussants: Stephen H. Little, Nina C. Wunderlich
1:00 PM Interventional Echocardiography: A New Subspecialty Created From Necessity Neil J. Weissman
1:09 PM TAVR: A Vast Frontier for Interventional Echo Stephen H. Little
1:21 PM Roundtable Discussion With Audience Q&A
1:26 PM The Changing Appearance of the Ideal MitraClip Patient: Imaging Is the Key Nina C. Wunderlich
1:38 PM Roundtable Discussion With Audience Q&A
1:43 PM Imagining New Devices: A Peak Into the Future Paul A. Grayburn
1:55 PM Roundtable Discussion With Audience Q&A
Fellows Session: Valvular Heart Disease Year-in-Review Accreditation: CME
Monday, October 12 1:00 PM - 2:00 PM Room: Moscone North, Lower Level, Room 125
Fellows Session: Valvular Heart Disease Year-in-Review 1:00 PM - 2:00 PM Moderators: Blase A. Carabello, Howard C. Herrmann Discussants: David H. Adams, Steven R. Bailey, Ted E. Feldman, A. Pieter Kappetein, Duane S. Pinto
1:00 PM Guideline Update: What’s New, and What’s Left Unsaid? Blase A. Carabello
1:10 PM TAVR 2015: Current Status James B. Hermiller Jr
1:20 PM What Will TAVR Look Like in 2 and 10 Years From Now? Duane S. Pinto
1:30 PM Transcatheter Mitral Therapies in 2015: MitraClip in Trials and the “Real World” Ted E. Feldman
1:40 PM Transcatheter Annuloplasty and Mitral Valve Replacement: Emerging Therapeutic Options Howard C. Herrmann
1:50 PM Roundtable Discussion With Audience Q&A
Late-Career Decisions for the “Experienced” Interventionalist Accreditation: CME
Monday, October 12 1:00 PM - 2:00 PM Room: Moscone North, Lower Level, Room 132
Late-Career Decisions for the “Experienced” Interventionalist 1:00 PM - 2:00 PM Moderator: David O. Williams Discussants: Peter C. Block, David R. Holmes Jr., Alice K. Jacobs, George W. Vetrovec
1:00 PM Life After Interventional Cardiology: Key Concerns David O. Williams
1:15 PM The Mayo Clinic Philosophy David R. Holmes Jr.
1:25 PM Roundtable Discussion With Audience Q&A
1:30 PM Late-Career Options for the Academic Interventionalist Alice K. Jacobs
1:40 PM Roundtable Discussion With Audience Q&A
1:45 PM Nearing Retirement? Impact on the Practicing Clinician George W. Vetrovec 1:55 PM Roundtable Discussion With Audience Q&A
Vulnerable Plaque Detection and Treatment Accreditation: CME/CNE
Monday, October 12 1:00 PM - 2:10 PM Room: Moscone North, Lower Level, Room 130
Vulnerable Plaque Detection and Treatment 1:00 PM - 2:10 PM Moderators: Gregg W. Stone, Renu Virmani Discussants: Patrick A. Calvert, David Erlinge, Farouc Jaffer, Gary S. Mintz, Evan A. Stein, Ron Waksman
1:00 PM Insights From BioImage: Vulnerable Plaque Is a Systemic Disease Roxana Mehran
1:10 PM What’s New in Coronary Vulnerable Plaque Detection: Noninvasive Imaging James K. Min
1:20 PM Integrative Imaging of Atherosclerotic Structure and Biology Ahmed A. Tawakol
1:30 PM The Intersection of Plaque Morphology and Endothelial Shear Stress: New Insights From PROSPECT Peter H. Stone
1:40 PM Will PCSK9 Inhibitors Transform the Natural History of Atherosclerosis? Philippe Gabriel Steg
1:50 PM Latest Concepts in Focal Vulnerable Plaque Stabilization: Scaffold Treatment Patrick W. Serruys
2:00 PM Roundtable Discussion With Q&A
Acute Infarct Angioplasty and Cardiogenic Shock Accreditation: CME/CNE
Monday, October 12 1:00 PM - 2:00 PM Room: Moscone North, Lower Level, Room 124 Acute Infarct Angioplasty and Cardiogenic Shock 1:00 PM - 2:00 PM Moderators: Jose P.S. Henriques, Thomas D. Stuckey Discussants: James A. Goldstein, Biswajit Kar, Christian M. Spaulding, Bernhard Witzenbichler
1:00 PM Treatment of Cardiogenic Shock With TandemHeart Case Presenter: Biswajit Kar
1:10 PM Discussion
1:15 PM Treatment of Cardiogenic Shock With Impella RP Case Presenter: James A. Goldstein
1:25 PM Discussion
1:30 PM Treatment of Cardiac Arrest With ECMO Case Presenter: Christian M. Spaulding
1:40 PM Discussion
1:45 PM Multivessel PCI in Cardiogenic Shock: When and How Case Presenter: Bernhard Witzenbichler
1:55 PM Discussion
Below-the-Knee Access Accreditation: CME/CNE
Monday, October 12 1:00 PM - 2:00 PM Room: Moscone North, Lower Level, Room 123
Below-the-Knee Access 1:00 PM - 2:00 PM Moderators: George L Adams, J. A. Mustapha Discussant: Andrej Schmidt
1:00 PM Transdigital Retrograde Access and Revascularization Case Presenter: J. A. Mustapha
1:15 PM Combined Tibiopedal Access With Transcollateral Revascularization Case Presenter: George L Adams
1:30 PM Angiography-Guided Proximal, Mid, and Distal Tibial Access Case Presenter: Andrej Schmidt
1:45 PM The Value of Antegrade/Retrograde Access and of Ultrasound-Guided Access Into Occluded Tibial Vessels Case Presenter: J. A. Mustapha Left Main Intervention Accreditation: CME/CNE
Monday, October 12 1:00 PM - 2:00 PM Room: Moscone North, Lower Level, Room 122
Left Main Intervention 1:00 PM - 2:00 PM Moderators: Francesco Burzotta, Marie-Claude Morice, Seung-Jung Park, Corrado Tamburino Discussants: Andrejs Erglis, David Hildick-Smith, Goran Stankovic
1:00 PM Case 1: The Simpler, the Better – Crossover With DES Case Presenter: Seung-Jung Park
1:10 PM Discussion: How Else Might This Have Been Treated?
1:15 PM Case 2: When I Need 2 Stents, I Prefer TAP Case Presenter: Francesco Burzotta
1:25 PM Discussion: How Else Might This Have Been Treated?
1:30 PM Case 3: A Left Main Intervention With BVS Case Presenter: Marie-Claude Morice
1:40 PM Discussion: Was BVS the Best Choice Here?
1:45 PM Case 4: Dedicated Stent for Left Main PCI Case Presenter: Corrado Tamburino
1:55 PM Discussion: Did This Stent Offer Any Advantage?
MitraClip Tips and Tricks Accreditation: CME/CNE
Monday, October 12 1:00 PM - 2:00 PM Room: Moscone North, Lower Level, Room 121
MitraClip Tips and Tricks 1:00 PM - 2:00 PM Moderator: Scott Lim Discussants: Anita Asgar, Nirat Beohar, Olaf Franzen, Samir R. Kapadia, Brij Maini 1:00 PM MitraClip Approach to Commissural Disease Case Presenter: Olaf Franzen
1:12 PM MitraClip Approach to Barlow's Disease Case Presenter: Samir R. Kapadia
1:24 PM Technique: Multiple-Clip Use Case Presenter: Anita Asgar
1:36 PM MitraClip Treatment of Very Tall/Wide Flails Case Presenter: Brij Maini
1:48 PM High Mitral Inflow Gradients After the First Clip Case Presenter: James B. Hermiller Jr
Nuts and Bolts of FFR, iFR, IMR, and CFR Accreditation: CME/CNE
Monday, October 12 1:00 PM - 2:00 PM Room: Moscone North, Lower Level, Room 120
Nuts and Bolts of FFR, iFR, IMR, and CFR 1:00 PM - 2:00 PM Moderator: Habib Samady Discussants: Justin E. Davies, William F. Fearon, Nico H.J. Pijls, Tim P. van de Hoef
1:00 PM Optimal FFR Technique: Case-Based Review of Guide Selection, Hyperemia, Wire Manipulation, Artifacts, Grey Zones, and Tracing Interpretation Case Presenter: Nico H.J. Pijls
1:12 PM FFR: Left Main, Serial Lesions, and ACS Cases Case Presenter: Habib Samady
1:24 PM iFR and Pd/Pa to Guide PCI in Diffuse and Multivessel CAD: A Case-Based Review Case Presenter: Justin E. Davies
1:36 PM Clinical Utility of CFR/IMR to Assess Microvasculature, Illustrated by Case Examples Case Presenter: Tim P. van de Hoef
1:48 PM When Do I Use FFR vs iFR vs IMR vs CFR? William F. Fearon iASSESS, Day 2 - Monday, Oct. 12 Accreditation: CME
Monday, October 12 8:00 AM - 6:00 PM Room: Moscone South, Lower Level, Room 103
iASSESS, Day 2: Morning Session 8:00 AM - 12:00 PM Moderators: George D. Dangas, Ajay J. Kirtane
8:00 AM Aspirin and ADP Antagonists Before and After Coronary Stent Implantation Moderator: Paul A. Gurbel Dmitriy N. Feldman
9:00 AM Valvular Heart Disease: Treatment of Mitral Stenosis and Mitral Regurgitation Moderator: Michael J. Lim Molly Szerlip
10:00 AM Valvular Heart Disease: Aortic Valvuloplasty and TAVR Moderator: Zoltan G. Turi Rahul Sakhuja
11:00 AM FFR, CFR, and PCI Moderator: Verghese Mathew Arnold Seto
iASSESS, Day 2: Afternoon Session 12:00 PM - 6:00 PM Moderators: Peter Barlis, Srihari S. Naidu
12:00 PM Intravascular Imaging: IVUS, OCT, and NIRS Moderator: John McB. Hodgson Allen Jeremias
1:00 PM Cardiogenic Shock and Hemodynamic Support Moderator: Manish A. Parikh Sahil A. Parikh
2:00 PM Structural Intervention: LAA Closure, HOCM, and Paravalvular Leak Moderator: Srihari S. Naidu Adnan K. Chhatriwalla
3:00 PM Complications of Coronary, Peripheral, and Structural Intervention Moderator: Morton J. Kern Mauricio G. Cohen
4:00 PM Congenital Heart Disease: PFO, ASD, VSD, and PDA Moderator: Harsimran Sachdeva Singh John P. Breinholt 5:00 PM Endovascular Interventions: Lower-Extremity, Aorta, Renal, and Carotid Disease Moderator: Kenneth Rosenfield Sahil A. Parikh
The European Practice of STEMI and NSTEMI Networks: Similarities and Differences Presented by the Working Group on Invasive and Interventional Cardiology, Croatian Cardiac Society; Working Group on Interventional Cardiology, German Cardiac Society; Belgian Working Group of Interventional Cardiology (BWGIC); Austrian Society of Cardiology; Swiss Working Group on Interventional Cardiology and Acute Coronary Syndrome, Working Group of Interventional Cardiology; Slovak Society of Cardiology, Working Group of Interventional Cardiology; and Czech Society of Cardiology Accreditation: none
Monday, October 12 8:30 AM - 10:30 AM Room: Moscone North, Lower Level, Presentation Theater 1
The European Practice of STEMI and NSTEMI Networks: Similarities and Differences 8:30 AM - 10:30 AM Moderators: Aleksander Ernst, Guy J. Friedrich Discussants: Walter Desmet, Petr Kala, Thomas Pilgrim, Martin Studencan, Jochen Wöhrle
8:30 AM Introduction Aleksander Ernst
8:35 AM ACS Networks in Austria Guy J. Friedrich
8:50 AM ACS Networks in Belgium Walter Desmet
9:05 AM ACS Networks in Croatia Hrvoje Pintaric
9:20 AM ACS Networks in the Czech Republic Petr Kala
9:35 AM ACS Networks in Germany Jochen Wöhrle
9:50 AM ACS Networks in Slovakia Martin Studencan
10:05 AM ACS Networks in Switzerland Thomas Pilgrim
10:20 AM Comments and Discussion Leader Guy J. Friedrich Novel Developments in Coronary Physiology Presented by the British Cardiovascular Intervention Society, Spanish Working Group on Interventional Cardiology, Italian Society of Invasive Cardiology (GISE), Dutch Working Group Interventional Cardiology, and Turkish Working Group of Interventional Cardiology Accreditation: none
Monday, October 12 9:00 AM - 10:30 AM Room: Moscone North, Lower Level, Presentation Theater 2
Novel Developments in Coronary Physiology 9:00 AM - 10:30 AM Moderators: Morton J. Kern, Jan J. Piek Justin E. Davies, Javier Escaned, Giampaolo Niccoli, Murat Sezer, Tim P. van de Hoef
9:00 AM The United Kingdom Presents: A Case of iFR for Evaluation of Serial Stenosis Using Pullback Case Presenter: Justin E. Davies
9:10 AM Roundtable Discussion With Audience Q&A
9:18 AM Spain Presents: A Case of iFR-FFR to Guide Coronary Revascularization in Multivessel Disease Case Presenter: Javier Escaned
9:28 AM Roundtable Discussion With Audience Q&A
9:36 AM Italy Presents: A Case Demonstrating the Diagnostic Workup in Nonobstructive Coronary Artery Disease Case Presenter: Giampaolo Niccoli
9:46 AM Roundtable Discussion With Audience Q&A
9:54 AM The Netherlands Presents: A Case Demonstration of Coronary Flow Capacity to Document Ischemic Heart Disease Case Presenter: Tim P. van de Hoef
10:04 AM Roundtable Discussion With Audience Q&A
10:12 AM Turkey Presents: A Case Assessing Microvascular Resistance in Non-STEMI Case Presenter: Murat Sezer
10:22 AM Roundtable Discussion With Audience Q&A
Complication Management During Complex Cardiovascular and Structural Interventions Presented by the Working Group on Interventional Cardiology, Cardiology Society of Serbia; FYR Macedonian Society of Cardiology; Hellenic Society Working Group on Interventional Cardiology; Cyprus Society of Cardiology; and Slovenian Working Group for Interventional Cardiology Accreditation: none
Monday, October 12 1:00 PM - 2:30 PM Room: Moscone West, 3rd Floor, Room 3024
Complication Management During Complex Cardiovascular and Structural Interventions 1:00 PM - 2:30 PM Moderators: Matjaz Bunc, Christos Christou, Sasko Kedev, Milan A. Nedeljkovic, Georgios Sianos, Sinisa Stojkovic Discussant: Miha Cercek
1:00 PM Introduction: CTO and TAVR in Everyday Practice Georgios Sianos
1:05 PM TAVR Complications: Case Reviews Case Presenter: Matjaz Bunc
1:17 PM Comments and Discussion Lead Discussant: Milan A. Nedeljkovic
1:22 PM TAVR Complications: Case Reviews Case Presenter: Matjaz Bunc
1:34 PM Comments and Discussion Lead Discussant: Christos Christou
1:39 PM Transradial CTO Intervention With Complications: Case Reviews Case Presenter: Sasko Kedev
1:51 PM Comments and Discussion Lead Discussant: Sinisa Stojkovic
1:56 PM CTO Intervention in ACS With Complications: Case Reviews Case Presenter: Georgios Sianos
2:04 PM Comments and Discussion Lead
2:14 PM Roundtable Discussion With Audience Q&A
2:28 PM Take-home Messages Christos Christou
High-Risk Intervention: Case-Based Intervention Around the World Presented by the Egyptian Society of Cardiology; Kuwait Cardiac Society; National Interventional Council, India; and the National Heart Association of Malaysia Accreditation: none
Monday, October 12 1:00 PM - 2:30 PM Room: Moscone West, 3rd Floor, Room 3020
High-Risk Intervention: Case-Based Intervention Around the World 1:00 PM - 2:30 PM Moderators: Mohammad Al-Mutairi, Amal Kumar Banerjee, Ahmed Magdy, Robaayah Zambahari Discussants: Praveen Chandra, Pravin K Goel, Sundeep Mishra
1:00 PM Egypt Presents: STEMI Interventions in a Patient With 3-Vessel Occlusion Case Presenter: Ahmed Magdy
1:12 PM Roundtable Discussion With Audience Q&A
1:22 PM Kuwait Presents: Complex Coronary Challenges Case Presenter: Mohammad Al-Mutairi
1:34 PM Roundtable Discussion With Audience Q&A
1:44 PM India Presents: Redo of Device Closure With Mitral Paravalvular Leak Case Presenter: Praveen Chandra
1:56 PM Roundtable Discussion With Audience Q&A
2:06 PM Malaysia Presents: Tangled Web – MitraClip Case Case Presenter: M Nasir Muda
2:18 PM Roundtable Discussion With Audience Q&A
Current PCI Controversies in Acute and Chronic Coronary Artery Disease Presented by the British Cardiovascular Intervention Society, South African Society of Cardiovascular Intervention, Russian Scientific Society of Endovascular Therapies, Scottish Cardiac Society Working Group, and the Irish Cardiac Society Accreditation: none
Monday, October 12 3:00 PM - 5:00 PM Room: Moscone North, Lower Level, Presentation Theater 1
Session I. Acute Coronary Syndrome 3:00 PM - 4:05 PM Moderators: Graham A. Cassel, Nick Curzen, Niall T. Mulvihill Discussants: Sergey A. Abugov, Bagrat Alekyan, David P. Foley, Margaret B. McEntegart, Darren Mylotte, Chris Andrew Zambakides
3:00 PM Introduction Niall T. Mulvihill 3:05 PM UK Presents: Nonculprit Vessel Disease in STEMI Nick Curzen
3:20 PM South Africa Presents: A Case of Double Acute Occlusion – Which Vessel to Open and When Case Presenter: Chris Andrew Zambakides
3:27 PM Russia Comments: How Would I Treat This Case? Bagrat Alekyan
3:33 PM South Africa Presents: How Did I Treat This Case? Case Presenter: Chris Andrew Zambakides
3:40 PM Scotland Presents: A Case of Bioresorbable Vascular Scaffold for Acute Plaque Rupture Case Presenter: Margaret B. McEntegart
3:47 PM Ireland Comments: How Would I Treat This Case? Darren Mylotte
3:53 PM Scotland Presents: How Did I Treat This Case? Case Presenter: Margaret B. McEntegart
4:00 PM Conclusion and Take-home Messages Nick Curzen
Session II. Chronic Coronary Artery Disease 4:05 PM - 5:00 PM Moderators: Graham A. Cassel, Nick Curzen, Niall T. Mulvihill Discussants: Sergey A. Abugov, Bagrat Alekyan, David P. Foley, Margaret B. McEntegart, Darren Mylotte, Chris Andrew Zambakides
4:05 PM South Africa Presents: Current Antiplatelet Therapy Riaz S Dawood
4:15 PM Ireland Presents: A Case of Double CTO in an Active Older Patient With Bypass Graft Failure Case Presenter: David P. Foley
4:22 PM Scotland Comments: How Would I Treat This Case? Margaret B. McEntegart
4:28 PM Ireland Presents: How Did I Treat This Case? Case Presenter: David P. Foley
4:35 PM Russia Presents: A Case of Early Stent Thrombosis in a Clopidogrel Low-Responder Patient Case Presenter: Sergey A. Abugov
4:42 PM Scotland Comments: How Would I Treat This Case? Margaret B. McEntegart
4:48 PM Russia Presents: How Did I Treat This Case? Moderator: Sergey A. Abugov
4:55 PM Conclusions and Take-home Message Graham A. Cassel
Optical Coherence Tomography in Bifurcation Lesions Presented by the Nordic-Baltic PCI Study Group for Interventional Cardiology Accreditation: none
Monday, October 12 3:00 PM - 5:00 PM Room: Moscone North, Lower Level, Presentation Theater 2
Session I. ”Simple” Bifurcation Treatment Guided by OCT 3:00 PM - 3:30 PM Moderators: Evald H. Christiansen, Andrejs Erglis Discussants: Niels R. Holm, Matti Jaakko Niemela, Terje K. Steigen
3:00 PM European Bifurcation Club Position on OCT in Bifurcations Jens Flensted Lassen
3:07 PM Case 1: Simple Stenting Technique, Carefully Executed Case Presenter: Olli A. Kajander
3:14 PM Case 2: OCT Guided Completion of Incomplete Bifurcation Stenting In a STEMI Setting Case Presenter: Ulf J Jensen
3:21 PM Roundtable Discussion With Audience Q&A
Session II. Two-Stent Techniques Optimized by OCT 3:30 PM - 4:00 PM Moderators: Evald H. Christiansen, Andrejs Erglis Discussants: Niels R. Holm, Matti Jaakko Niemela, Terje K. Steigen
3:30 PM Case 3: Two-Stent Treatment Using Stepwise OCT Case Presenter: Anssi M Perälä
3:37 PM Case 4: Where Are the Guidewires? Two-Stent Treatment Guided by OCT Case Presenter: Michael Maeng
3:44 PM Case 5: This DK-CRUSH Was Saved by OCT Case Presenter: Shao-Liang Chen 3:51 PM Roundtable Discussion With Audience Q&A
Session III. Always Use OCT When Implanting Bioresorbable Vascular Scaffolds in Bifurcations 4:00 PM - 4:30 PM Moderators: Evald H. Christiansen, Andrejs Erglis Discussants: Niels R. Holm, Matti Jaakko Niemela, Terje K. Steigen
4:00 PM Case 6: I Use OCT in (Almost) All Steps of BRS Treatment Case Presenter: Gustavs Latkovskis
4:07 PM Case 7: Procedural Issues and Early Healing Response After OCT-Guided Bifurcation Treatment Using BRS Case Presenter: Niels R. Holm
4:14 PM Case 8: Successful OCT-Guided 2-Stent Treatment Using BRS Case Presenter: Maciej Lesiak
4:21 PM Roundtable Discussion With Audience Q&A
Session VI. OCT in Left Main Intervention 4:30 PM - 5:00 PM Moderators: Evald H. Christiansen, Andrejs Erglis Discussants: Niels R. Holm, Matti Jaakko Niemela, Terje K. Steigen
4:30 PM Case 9: OCT Is Feasible and Instrumental in Left Main Bifurcation Treatment Case Presenter: Julian Strange
4:37 PM Case 10: OCT in Distal LM Lesion Ambiguity Case Presenter: Evald H. Christiansen
4:44 PM Case 11: OCT for the Left Main DES-BRS Hybrid Strategy Case Presenter: Indulis Kumsars
4:51 PM Summary Evald H. Christiansen
Featured Clinical Research I: Presentations to the Editors of the Journal of the American College of Cardiology Accreditation: CME
Monday, October 12 12:15 PM - 1:45 PM Room: Moscone South, Lower Level, Room 104 Presentations to the Editors of the Journal of the American College of Cardiology 12:15 PM - 1:45 PM Moderators: Spencer B. King III, Jagat Narula Discussants: Vasilis Babaliaros, Y S Chandrashekhar
12:15 PM OPEN CTO: Evaluation of a Hybrid Approach to Chronic Total Occlusion Coronary Intervention J. Aaron Grantham
12:25 PM Roundtable Discussion With Audience Q&A
12:30 PM CoreValve US Extreme Risk: Evaluation of a Self-Expanding Transcatheter Aortic Valve in Patients With Severe Aortic Stenosis at Extreme Risk for Surgery James B. Hermiller Jr
12:40 PM Roundtable Discussion With Audience Q&A
12:45 PM DAPT: A Prospective, Double-blind, Placebo-controlled Randomized Trial of 1-year Versus 2.5 Years of Dual Anti-platelet Therapy (Everolimus-Eluting Stent-Treated Subset)” James B. Hermiller Jr
12:55 PM Roundtable Discussion With Audience Q&A
1:00 PM PROMISE FFR-CT: Evaluation of FFR-CT in Patients Undergoing Computed Tomographic Angiography for Evaluation of Suspected Coronary Artery Disease Michael Lu
1:10 PM Roundtable Discussion With Audience Q&A
1:15 PM CENTURY II: A Prospective Randomized Trial of a Bioabsorbable-Polymer Biolimus- Eluting Stent Versus a Durable-Polymer Everolimus-Eluting Stent in Patients With Coronary Artery Disease – Two-Year Outcomes Shigeru Saito
1:25 PM Roundtable Discussion With Audience Q&A
1:30 PM The TRYTON PIVOTAL: Randomized Trial and Confirmatory Study: Dedicated Bifurcation Stent in Coronary Bifurcation Involving Large Side Branches Philippe Généreux
1:40 PM Roundtable Discussion With Audience Q&A
Are You Prepared for Bioresorbable Scaffolds? Technical and Clinical Considerations for BRS: Integrating Intravascular Imaging Into Your Practice (Sponsored by Volcano Philips) Accreditation: none
Monday, October 12 6:30 AM - 8:00 AM Room: Moscone North, Lower Level, Room 125 Check-In and Breakfast 6:30 AM - 7:00 AM
Are You Prepared for Bioresorbable Scaffolds? Technical and Clinical Considerations for BRS: Integrating Intravascular Imaging Into Your Practice 7:00 AM - 8:00 AM Chairs: Akiko Maehara, Gary S. Mintz Facultys: Hiroshi Kawamoto, MD, Shimpei Nakatani, MD, Bruce Samuels
7:00 AM Mechanical Properties of Bioresorbable Scaffolds Assessed by Intravascular Imaging: What Does the Interventional Cardiologist Need to Know? Shimpei Nakatani
7:15 AM Lessons From 300 Bioresorbable Scaffold Implantation Cases With IVUS: What Imaging and Patient Outcome Goals Should We Set With BRS? Hiroshi Kawamoto
7:30 AM A New Precision-Guided Workflow With SyncVision® IVUS Co-registration and Enhanced Angiographic Imaging: What Are the Implications in a Value-Based Health Care System? Bruce Samuels
7:45 AM Question and Answer
Complex PCI Procedures: A Discussion of Clinical Cases Using Visipaque™ (Iodixanol) Injection, the Isosmolar Contrast Agent (Sponsored by GE Healthcare) Accreditation: none
Monday, October 12 6:30 AM - 8:00 AM Room: Moscone North, Lower Level, Room 131
Check-In and Breakfast 6:30 AM - 7:00 AM
Complex PCI Procedures: A Discussion of Clinical Cases Using Visipaque™(Iodixanol) Injection, the Isosmolar Contrast Agent 7:00 AM - 8:00 AM Facultys: Emmanouil S. Brilakis, Lauren Lim
7:00 AM GE Healthcare Welcome
7:05 AM Visipaque Overview
7:10 AM Introduction: Complex and High-Risk Indicated PCI “CHIP” Cases Emmanouil S. Brilakis
7:15 AM CASE 1: PCI of Last Two Remaining Vessels 7:30 AM Questions & Answers
7:35 AM CASE 2: Chasing Rabbit Tails
7:50 AM Questions & Answers
7:55 AM Closing Remarks
Managing Atrial Fibrillation and Chronic Anticoagulant Therapy in Patients Undergoing PCI: An Expert Consensus (Sponsored by the Cardiovascular Research Foundation) (Supported by Boston Scientific Corporation and Medtronic, Inc.) Accreditation: none
Monday, October 12 6:30 AM - 8:00 AM Room: Moscone North, Lower Level, Room 120
Check-in and Breakfast 6:30 AM - 7:00 AM
Managing Atrial Fibrillation and Chronic Anticoagulant Therapy in Patients Undergoing PCI: An Expert Consensus 7:00 AM - 8:00 AM Chairs: Roxana Mehran, Brian K. Whisenant Facultys: Deepak L. Bhatt, C. Michael Gibson, William A. Gray, Stephen D. Wiviott
7:00 AM Welcome and Introduction Chair: Roxana Mehran
7:03 AM The Fine Balance of Stroke Prevention and Bleeding for Patients With A-fib Undergoing PCI: How Do Interventional Cardiologists Choose? Roxana Mehran
7:11 AM Role of Novel Anticoagulants in Patients With A-fib Undergoing PCI: Is There Consensus? Stephen D. Wiviott
7:25 AM Optimizing the Anticoagulation Regimen in PCI Patients With Chronic A-fib: The PIONEER A-fib Study – Rationale and Design C. Michael Gibson
7:32 AM Optimizing the Anticoagulation Regimen in PCI Patients With Chronic A-fib: The RE- DUAL Study – Rationale and Design Deepak L. Bhatt
7:40 AM Interventional Approaches to Stroke Prevention in Patients With A-fib: Who? William A. Gray
7:48 AM Discussion With Audience Q&A Mitral Regurgitation Interventions: Measuring Today’s Success and Guiding Tomorrow’s Evolution (Supported through an educational grant from Abbott) Accreditation: none
Monday, October 12 6:30 AM - 8:00 AM Room: Moscone North, Lower Level, Room 121
Check-in and Breakfast 6:30 AM - 7:00 AM
Mitral Regurgitation Interventions: Measuring Today’s Success and Guiding Tomorrow’s Evolution 7:00 AM - 8:00 AM Chair: Alec S. Vahanian Facultys: William T. Abraham, John D. Carroll, A. Pieter Kappetein
7:00 AM Mitral Valve Interventions: The Evolution of Treatment Options Alec S. Vahanian
7:05 AM Quality of Life is the Key Clinical Metric in Treating Secondary MR William T. Abraham
7:15 AM Discussion
7:20 AM Elimination of MR is the Key Metric in Treatment of MR A. Pieter Kappetein
7:30 AM Discussion
7:35 AM Roundtable Discussion with Audience Q&A: Surgery vs. Transcatheter MV Repair vs. Transcatheter MV Replacement; Ongoing Clinical Trials; MVARC Caveats and Consensus
Parachute: A Structural Heart Device for Heart Failure (Sponsored by CardioKinetix, Inc.) Accreditation: none
Monday, October 12 6:30 AM - 8:00 AM Room: Moscone North, Lower Level, Room 130
Check-In and Breakfast 6:30 AM - 7:00 AM Parachute: A Structural Heart Device for Heart Failure 7:00 AM - 8:00 AM Chair: Marco A. Costa Facultys: Brij Maini, Teguh Santoso
7:00 AM Parachute Therapy Overview Brij Maini
7:15 AM Parachute Pooled Analysis and Hemodynamics Karl-Heinz Kuck
7:30 AM Southeast Asia Experience Teguh Santoso
7:45 AM PARACHUTE IV Trial Update Marco A. Costa
Simplify FFR for Your Practice. New Approaches to Rapid Pressure Measurement (Sponsored by ACIST Medical Systems and Medtronic, PLC) Accreditation: none
Monday, October 12 6:30 AM - 8:00 AM Room: Moscone North, Lower Level, Room 123
Check-in and Breakfast 6:30 AM - 7:00 AM
Simplify FFR for Your Practice. New Approaches to Rapid Pressure Measurement 7:00 AM - 8:00 AM Chair: Morton J. Kern Facultys: Nils Johnson, Marco Valgimigli
7:00 AM FFR: Current Practices and New Approaches Morton J. Kern
7:10 AM The Role of Hyperemia in Physiological Assessments Nils Johnson
7:30 AM Navvus® MicroCatheter for FFR Guidance in Multivessel Disease Marco Valgimigli
7:50 AM Q&A Moderator: Morton J. Kern Transforming TAVR (Sponsored by Edwards Lifesciences) Accreditation: none
Monday, October 12 6:30 AM - 8:00 AM Room: Moscone North, Lower Level, Room 124
Check-in and Breakfast 6:30 AM - 7:00 AM
Transforming TAVR 7:00 AM - 8:00 AM Chair: Martin B. Leon Faculty: Laksen Sirimanne
7:00 AM The Power of Definitive Data Martin B. Leon
7:40 AM The Power of Transformational Design Laksen Sirimanne
Treatment of Complex Higher-Risk Patients: Introduction to Protected PCI (Sponsored by the Cardiovascular Research Foundation) (Supported through a grant from ABIOMED, Inc.) Accreditation: none
Monday, October 12 6:30 AM - 8:00 AM Room: Moscone North, Lower Level, Room 122
Check-in and Breakfast 6:30 AM - 7:00 AM
Treatment of Complex Higher-Risk Patients: Introduction to Protected PCI 7:00 AM - 8:00 AM Chair: John M. Lasala Facultys: William L. Lombardi, Jeffrey W. Moses, William W. O'Neill
7:00 AM The Growing Need for Complex High-Risk Interventional Procedures John M. Lasala
7:05 AM Current Trends in PCI Procedures Performed in the US Jeffrey W. Moses
7:15 AM Protected PCI: Expanding Options for Complex Patient Subsets William L. Lombardi
7:25 AM Clinical Outcomes With Protected PCI: PROTECT II and Beyond
7:50 AM Discussion and Summary
DAPT and Beyond: A Case-Based Guide to Optimal Antiplatelet Therapies (Sponsored by the Cardiovascular Research Foundation) (Supported by Abbott Vascular, AstraZeneca, Boston Scientific Corporation, and Medtronic, Inc.) Accreditation: none
Monday, October 12 6:00 PM - 8:00 PM Room: Hilton Union Square, Ballroom Level, Continental Ballroom 5-6
Chairs: Ajay J. Kirtane, Roxana Mehran Facultys: Eric R. Bates, John A. Bittl, George D. Dangas, James B. Hermiller Jr, Philippe Gabriel Steg
Check-in and Reception 6:00 PM - 6:30 PM
Welcome, Introductions, and Session Goals 6:30 PM - 6:35 PM Chair: Roxana Mehran
DEBATE: DURATION OF DAPT 6:35 PM - 7:00 PM Discussants: Eric R. Bates, John A. Bittl, George D. Dangas, James B. Hermiller Jr, Ajay J. Kirtane, Roxana Mehran, Philippe Gabriel Steg
6:35 PM Shorter Is Better Ajay J. Kirtane
6:40 PM Longer Is Safer Eric R. Bates
6:45 PM Commentary: How Do You Balance Bleeding Risk and Ischemic Benefit? John A. Bittl
6:50 PM Roundtable Discussion
REAL-WORLD CASES 7:00 PM - 8:00 PM Discussants: Eric R. Bates, John A. Bittl, George D. Dangas, James B. Hermiller Jr, Ajay J. Kirtane, Roxana Mehran, Philippe Gabriel Steg
7:00 PM Case 1: A Complex Bifurcation PCI in an Elderly Woman James B. Hermiller Jr
7:05 PM Panel and Synthesis
7:15 PM Case 2: An Elderly Patient Who Requires Urgent Major Hip Surgery After PCI Ajay J. Kirtane
7:20 PM Panel and Synthesis
7:30 PM Case 3: A Patient Who Develops A-fib After TAVR George D. Dangas
7:35 PM Panel and Synthesis
7:45 PM Case 4: Patient With High Ischemic and Bleeding Risks Philippe Gabriel Steg
7:50 PM Panel and Synthesis
Emerging Interventional Technologies That May Shift the Treatment Paradigm: Synergy and Watchman (Sponsored by Boston Scientific Corporation) Accreditation: none
Monday, October 12 6:00 PM - 8:00 PM Room: Hilton Union Square, Grand Ballroom Level, Grand Ballroom B
Check-in and Reception 6:00 PM - 6:30 PM
Emerging Interventional Technologies That May Shift the Treatment Paradigm: Synergy and Watchman 6:30 PM - 8:00 PM Chair: Martin B. Leon Facultys: David R. Holmes Jr., Saibal Kar, Dean J. Kereiakes, Ian T. Meredith, Vivek Y. Reddy, Mark Reisman, Jose M. de la Torre Hernandez
6:30 PM Welcome, Symposium Format, and Intro to Hosts Chair: Martin B. Leon
6:35 PM Recognition Segment #1
6:45 PM SYNERGY Moderated Discussion Moderator: Martin B. Leon Discussants: Dean J. Kereiakes, Ian T. Meredith, Jose M. de la Torre Hernandez
7:05 PM Recognition Segment #2
7:10 PM Watchman Moderated Discussion Moderator: Martin B. Leon Discussants: David R. Holmes Jr., Saibal Kar, Mark Reisman
7:30 PM Recognition Segment #3
7:35 PM Closing Thoughts/Comments
Knights of the Roundtable 2015: Stop the Madness! (Sponsored by the Cardiovascular Research Foundation) (Supported by AstraZeneca, Boston Scientific Corporation, The Medicines Company and Medtronic, Inc.,) Accreditation: none
Monday, October 12 6:00 PM - 8:00 PM Room: Hilton Union Square, Ballroom Level, Continental Ballroom 1-4
Chairs: Cindy L. Grines, Philippe Gabriel Steg, Gregg W. Stone Facultys: David A. Cox, Jose P.S. Henriques, Sanjit S. Jolly, Elmir Omerovic, Duane S. Pinto, Barry D. Rutherford, Daniel I. Simon, Thomas D. Stuckey, Holger Thiele, David A. Wood
Check-in and Reception 6:00 PM - 6:30 PM
Section I. Routine Thrombus Aspiration: Dead or Alive? 6:30 PM - 7:00 PM Discussants: David A. Cox, Cindy L. Grines, Jose P.S. Henriques, Sanjit S. Jolly, Elmir Omerovic, Duane S. Pinto, Barry D. Rutherford, Daniel I. Simon, Philippe Gabriel Steg, Gregg W. Stone, Thomas D. Stuckey, Holger Thiele
6:30 PM The Data Are In: No Benefit and Possible Harm (and Expense)! Sanjit S. Jolly
6:37 PM Not So Fast: New Insights From SCAAR! Elmir Omerovic
6:44 PM Case Presentation: STEMI With Thrombus – To Aspirate, or Not to Aspirate? Thomas D. Stuckey
6:50 PM Roundtable Discussion With Audience Q&A
Section II. Immediate, Early, or Deferred Revascularization of Nonculprit Lesions 7:00 PM - 7:26 PM Discussants: David A. Cox, Cindy L. Grines, Jose P.S. Henriques, Sanjit S. Jolly, Elmir Omerovic, Duane S. Pinto, Barry D. Rutherford, Daniel I. Simon, Philippe Gabriel Steg, Gregg W. Stone, Thomas D. Stuckey, Holger Thiele
7:00 PM The Horse is Out of the Barn: Time for Rapid Early Revascularization! Jose P.S. Henriques 7:08 PM Routine Early Revascularization May be the Next COURAGE: Wait for the COMPLETE Answer! David A. Wood
7:16 PM Roundtable Discussion With Audience Q&A
Section III. Bivalirudin, Cangrelor and Ticagrelor in STEMI: The Perfect Marriage? 7:26 PM - 8:00 PM
7:26 PM The Data Are In: Reduce Bleeding, Prevent Stent Thrombosis, Save Lives! Gregg W. Stone
7:34 PM There Are Better Antithrombotic/Antiplatelet Combinations Than This! Daniel I. Simon
7:42 PM Roundtable Discussion With Audience Q&A Discussant: Elmir Omerovic
7:52 PM Roundtable Discussion With Audience Q&A
Section IV. Open Microphone Q&A Session From the Audience: What’s on Your Mind? 7:56 PM - 8:00 PM
The PCI Future Today: Bioresorbable Vascular Scaffolds (Sponsored by the Cardiovascular Research Foundation) (Supported by Abbott) Accreditation: none
Monday, October 12 6:00 PM - 8:00 PM Room: Hilton Union Square, Ballroom Level, Imperial Ballroom AB
Check-in and Reception 6:00 PM - 6:30 PM
The PCI Future Today: Bioresorbable Vascular Scaffolds 6:30 PM - 8:00 PM Chairs: Patrick W. Serruys, Gregg W. Stone Facultys: Bernard R. Chevalier, Dariusz Dudek, Stephen G. Ellis, Dean J. Kereiakes, Corrado Tamburino, Ron Waksman
6:30 PM The Transformative Landscape of Bioresorbable Vascular Scaffolds Ron Waksman
6:40 PM ABSORB III Pivotal Study Results (Beyond the Late-Breaking Clinical Trial) Stephen G. Ellis 6:55 PM ABSORB Meta-analysis: 1-year Outcomes From a Patient-level Meta-analysis of the 4 Randomized ABSORB Trials Gregg W. Stone
7:10 PM Insights From Long-term Follow-up: Two-Year Results From ABSORB II Bernard R. Chevalier
7:20 PM Why BRS Treatment Today Should Improve Long-term Outcomes: Final 5-Year Cohort-B Imaging Results Patrick W. Serruys
7:30 PM Procedural Pearls to Optimize BRS Outcomes: A Case-Based Review Corrado Tamburino
7:45 PM Roundtable Discussion With Audience Q&A
Edited Taped Cases I: Novel Valve and Structural Heart Procedures Accreditation: none
Monday, October 12 9:00 AM - 10:40 AM Room: Presentation Theater 3, Moscone South, Lower Level, Exhibit Hall
Edited Taped Cases I: Novel Valve and Structural Heart Procedures 9:00 AM - 10:40 AM Moderators: Reginald I. Low, Stephen G. Worthley Discussants: Saif Anwaruddin, Dharam J. Kumbhani
9:00 AM TAVI with Medtronic Evolut R with EnVeo R in a Patient with Severe Aortic Stenosis and Mechanical Mitral Prosthesis Caterina Gandolfo
9:12 AM Roundtable Discussion With Audience Q&A
9:20 AM Innovative Percutaneous Solution to Treat Tricuspid Valve Disease Azeem Latib
9:32 AM Roundtable Discussion With Audience Q&A
9:40 AM Direct Aortic Valve in Valve Implantation with the Corevalve Evolut R with EnVeo R for Small Degenerated Mitroflow Bioprosthesis Caterina Gandolfo
9:52 AM Roundtable Discussion With Audience Q&A
10:00 AM ARTO System Andrejs Erglis
10:12 AM Roundtable Discussion With Audience Q&A 10:20 AM Self-Positioning Transseptal Steerable System for Left Atrial Access and Catheter Ablation Francesco Maisano
10:32 AM Roundtable Discussion With Audience Q&A
Edited Taped Cases II: Complex PCI Accreditation: none
Monday, October 12 10:00 AM - 10:40 AM Room: Presentation Theater 4, Moscone South, Lower Level, Exhibit Hall
Edited Taped Cases II: Complex PCI 10:00 AM - 10:40 AM Moderators: Ronald Caputo, Arnold Seto Discussants: Fernando Cura, Frederick Kushner
10:00 AM PCI with CPR Maddury Jyotsna
10:12 AM Roundtable Discussion With Audience Q&A
10:20 AM Broken Catheter, Retrieval and Successful PCI Maddury Jyotsna
10:32 AM Roundtable Discussion With Audience Q&A
Case Discussions: Techniques to Access, Cross, and Treat Complex In-Stent Restenosis Lesions (Sponsored by Gore) Accreditation: none
Monday, October 12 11:30 AM - 12:30 PM Room: Moscone South, Lower Level, Exhibit Hall, Presentation Theater 4
Case Discussions: Techniques to Access, Cross, and Treat Complex In-Stent Restenosis Lesions 11:30 AM - 12:30 PM Facultys: George L Adams, Robert M. Bersin, John R. Laird Jr, Peter A. Soukas, MD
11:30 AM Cases Discussions Moderator: George L Adams Case Presenters: Robert M. Bersin, John R. Laird Jr, Peter A. Soukas, MD Debate: Vessel Preparation – Is It Needed in the Modern Era of PCI? (Sponsored by Cardiovascular Systems, Inc.) Accreditation: none
Monday, October 12 11:30 AM - 12:30 PM Room: Moscone North, Lower Level, Hall D, Presentation Theater 2
Debate: Vessel Preparation – Is It Needed in the Modern Era of PCI? 11:30 AM - 12:30 PM Facultys: Jeffrey Chambers, Jeffrey W. Moses, Sunil V. Rao, Richard Shlofmitz
11:30 AM A Case-based Debate on Different Strategies to Vessel Preparation, Image Guided Therapy, and How to Make Complex Calcified PCI's More Routine
Durable vs Bioabsorbable Polymers: Addressing the Unmet Clinical Need (Sponsored by Abbott) Accreditation: none
Monday, October 12 11:30 AM - 12:30 PM Room: Moscone North, Lower Level, Hall D, Presentation Theater 1
Durable vs Bioabsorbable Polymers: Addressing the Unmet Clinical Need 11:30 AM - 12:30 PM Facultys: Sripal Bangalore, James B. Hermiller Jr, David G. Rizik, Renu Virmani
11:30 AM Why XIENCE is the Gold Standard of Permanent Metallic Implants: Examining the Promise of BP-DES Sripal Bangalore
11:42 AM New Pre-Clinical Perspective of Metallic DES Renu Virmani
11:54 AM XIENCE's Performance During DAPT Interruption/Discontinuation James B. Hermiller Jr
12:06 PM Understanding Absorb and the Next Revolution in PCI David G. Rizik
12:18 PM Q&A Moderator: David G. Rizik Strategies to Cross, Prep, and Treat Complex Disease (Sponsored by Spectranetics) Accreditation: none
Monday, October 12 11:30 AM - 12:30 PM Room: Moscone South, Lower Level, Exhibit Hall, Presentation Theater 3
Strategies to Cross, Prep, and Treat Complex Disease 11:30 AM - 12:30 PM Chair: William L. Lombardi Facultys: Takashi Ashikaga , MD, Azeem Latib, Hoang Thai MD, R. Michael Wyman
11:30 AM Welcome Chair: William L. Lombardi
11:35 AM Crossing CTO’s with Advanced Techniques and Technology R. Michael Wyman
11:45 AM Preparing the Coronary Lesion for BVS Implantation Azeem Latib
11:55 AM Complex Coronary ISR with OCT Follow Up Takashi Ashikaga , MD
12:05 PM Case Experience with ELCA and AngioSculpt Followed by OCT Hoang Thai, MD
12:15 PM Question and Answer
Direct Flow Medical: From an Innovative TAVR System to a Structural Heart Platform (Sponsored by Direct Flow Medical) Accreditation: none
Monday, October 12 1:00 PM - 2:00 PM Room: Moscone North, Lower Level, Hall D, Presentation Theater 2
Direct Flow Medical: From an Innovative TAVR System to a Structural Heart Platform 1:00 PM - 2:00 PM Chair: Jeffrey J. Popma Facultys: Federico De Marco, MD, Azeem Latib, William W. O'Neill
1:00 PM Introduction
1:05 PM Current Evidence and Clinical Program Update William W. O'Neill 1:15 PM Live in a Box With Advance Techniques Federico De Marco, MD
1:30 PM Technology Outlook and Future Perspectives Azeem Latib
1:40 PM Discussion and Audience Interaction
1:55 PM Key Learnings and Closing Remarks Jeffrey J. Popma
Left Atrial Appendage Closure: Outstanding Data, Outstanding Questions (Sponsored by the Cardiovascular Research Foundation) (Supported by SentreHEART, Inc.) Accreditation: CME
Monday, October 12 1:00 PM - 2:00 PM Room: Moscone North, Lower Level, Hall D, Presentation Theater 1
Left Atrial Appendage Closure: Outstanding Data, Outstanding Questions 1:00 PM - 2:00 PM Chair: William A. Gray Facultys: Ori Ben-Yehuda, Randall J. Lee, Brian K. Whisenant, Steven J. Yakubov
1:00 PM Welcome and Introductions William A. Gray
1:05 PM Left Atrial Appendage (LAA) Occlusion in Oral Anticoagulation–Ineligible Patients: Who Should Be Considered, and How Frequent Are They? Ori Ben-Yehuda
1:17 PM What Are the Current Alternatives – Investigational and Approved – To the Watchman Approach? Steven J. Yakubov
1:29 PM After the Watchman Trials: What Regulatory Pathway Options Are Relevant (and Achievable!)? Brian K. Whisenant
1:41 PM Ligation Meets Ablation: Early Data on the Synergistic Effects of PV Ablation With LAA Ligation and the AMAZE Trial Randall J. Lee
1:53 PM Discussion WATCHMAN Patient Selection Panel Discussion (Sponsored by Boston Scientific Corporation) Accreditation: none
Monday, October 12 1:00 PM - 2:00 PM Room: Moscone South, Lower Level, Exhibit Hall, Presentation Theater 4
WATCHMAN Patient Selection Panel Discussion 1:00 PM - 2:00 PM Chair: Matthew J. Price
1:00 PM Panel Discussion on These Topics: Stroke Risk Treatment Decision – Challenges With OAC – WATCHMAN Indications for Use – WATCHMAN Experience – WATCHMAN’s Impact on Patient Lives – Why WATCHMAN? – Patient Selection – Patient Education – Referring Physician
You Can Get There From Here: How to Succeed at CTO PCI (Sponsored by Abbott) Accreditation: none
Monday, October 12 1:00 PM - 2:00 PM Room: Moscone South, Lower Level, Exhibit Hall, Presentation Theater 3
You Can Get There From Here: How to Succeed at CTO PCI 1:00 PM - 2:00 PM Moderator: William L. Lombardi Facultys: J. Aaron Grantham, William Nicholson, James C. Spratt
1:00 PM Evolution of a CTO Operator J. Aaron Grantham
1:20 PM Evolution of a CTO Program William Nicholson
1:40 PM Evolution in Training: Retrograde CTO-PCI iBook James C. Spratt
Interactive Technology Center: Hands on Hearts Accreditation: none Monday, October 12 8:00 AM - 2:00 PM Room: Moscone North, Lower Level, Hall D
Hands on Hearts 8:00 AM - 2:00 PM Discussants: Tobias Koppara, Robert Kutys, Elena Ladich, Michelle Olson, Maria E. Romero
ITC and Demonstration Theater - LAA and MitraClip Accreditation: none
Monday, October 12 9:00 AM - 12:00 PM Room: Moscone North, Lower Level, Demonstration Theater, Hall D
Session I. Left Atrial Appendage Occlusion 9:00 AM - 10:40 AM Moderators: Ted E. Feldman, Matthew J. Price Discussants: Philipp Blanke, Samir R. Kapadia, G. Burkhard Mackensen, Mark Reisman, Jacqueline Saw
9:00 AM Practical CT Reading and Analysis Sequence Philipp Blanke
9:10 AM Practical Echo Reading and Analysis Sequence G. Burkhard Mackensen
9:20 AM Roundtable Discussion with Audience Q&A
9:30 AM Anatomical Landmarks and Considerations for Trans-Septal Crossing in LAA Intervention Mark Reisman
9:40 AM The Trans-Septal Technique: A Step-Wise Interactive Demonstration Samir R. Kapadia
9:50 AM Intra-Procedural Echo Guidance and Procedural Approach G. Burkhard Mackensen
10:00 AM Roundtable Discussion with Audience Q&A
10:10 AM Hands-On-Technology Demonstration: Watchman Matthew J. Price
10:20 AM Hands-On-Technology Demonstration: Amplatzer Cardiac Plug Jacqueline Saw
10:30 AM Roundtable Discussion with Audience Q&A Session II. MitraClip 10:40 AM - 12:00 PM Moderators: Ted E. Feldman, Brij Maini Discussants: John D. Carroll, Paul A. Grayburn, Mark Reisman
10:40 AM Practical Echo Reading and Analysis Sequence G. Burkhard Mackensen
10:50 AM Anatomical Landmarks and Considerations for Trans-Septal Crossing and MitraClip Use Mark Reisman
11:00 AM Roundtable Discussion with Audience Q&A
11:10 AM Patho-Anatomy of the Left Atrium and Mitral Valve Apparatus: Implications for Interventional Therapies Mark Reisman
11:20 AM Intra-Procedural Echo Guidance in MitraClip Procedures G. Burkhard Mackensen
11:30 AM Roundtable Discussion with Audience Q&A
11:40 AM Hands-On-Technology Demonstration: MitraClip Ted E. Feldman
11:45 AM Roundtable Discussion with Audience Q&A
CRF Pavilion Program Accreditation: none
Monday, October 12 9:00 AM - 3:00 PM Room: Moscone South, Lower Level, CRF Pavilion
CRF Pavilion Program 9:00 AM - 3:00 PM
9:00 AM Live Stream Live Case from Coronary Theatre: Live Cases: LM/Bifurcations with San Rafaele Hospital, Milan, Italy
10:30 AM Discussion with CRF Global Partner, Bangla Interventional Therapeutics Discussants: Rabin dra Nath Chakraborty, Ivo Petrov, Marin Postu
11:00 AM CRF Clinical Trials Center presents "CRF's Approach to Product Development" Ori Ben-Yehuda Discussants: Ioanna Kosmidou, Laura LaSalle, Akiko Maehara, Melissa Nichols
11:30 AM CRF Clinical Trials Center presents "Funding Research From a VC Perspective" Tamir Wolf Discussant: Ori Ben-Yehuda
2:00 PM Skirball Center for Innovation and Diagnostic and Interventional Cardiology Ad Interview Key Opinion Leaders
Digital Zone - TECH Talks I Accreditation: none
Monday, October 12 11:00 AM - 3:30 PM Room: Moscone South, Lower Level, Digital Zone, Exhibit Hall
Featured TECH Talk 11:00 AM - 11:30 AM
11:00 AM Digital Zone’s Featured Tech Talk Peter J. Fitzgerald
11:15 AM Q&A
Alivecor 11:30 AM - 12:00 PM
Augmedix 12:00 PM - 12:30 PM
Break 12:30 PM - 2:00 PM
CardioSecur 2:00 PM - 2:30 PM
CathWorks 2:30 PM - 3:00 PM
Eko Devices 3:00 PM - 3:30 PM
Meet the Trialists I Accreditation: CME/CNE Monday, October 12 2:00 PM - 3:15 PM Room: Moscone West, 3rd Floor, Room 3000
Meet the Trialists 2:00 PM - 3:15 PM Moderator: Ioanna Kosmidou Discussants: Saif Anwaruddin, Melissa Nichols, Jordan Safirstein
2:00 PM ABSORB III: A Prospective Randomized Trial of an Everolimus-Eluting Bioresorbable Scaffold Vs. an Everolimus-Eluting Metallic Stent in Patients With Coronary Artery Disease Dean J. Kereiakes
2:05 PM Roundtable Discussion With Audience Q&A
2:15 PM ABSORB China: A Prospective Randomized Trial of an Everolimus-Eluting Bioresorbable Scaffold vs an Everolimus-Eluting Metallic Stent in Patients With Coronary Artery Disease Run-Lin Gao
2:20 PM Roundtable Discussion With Audience Q&A
2:30 PM ABSORB II: A Prospective Randomized Trial of an Everolimus-Eluting Bioresorbable Scaffold Vs. an Everolimus-Eluting Metallic Stent in Patients With Coronary Artery Disease - Two-Year Outcomes Bernard R. Chevalier
2:35 PM Roundtable Discussion With Audience Q&A
2:45 PM LBCT- A Prospective Randomized Trial of Transradial vs Transfemoral Access in Patients Undergoing Coronary Angiography and Intervention Shigeru Saito
2:50 PM Roundtable Discussion With Audience Q&A
3:00 PM BIOSOLVE II: Evaluation of a Sirolimus-Eluting Bioresorbable Metallic Scaffold - Six- Month Clinical, Angiographic and Imaging Outcomes Michael Haude
3:05 PM Roundtable Discussion With Audience Q&A
TCT 2015 Exhibit Hall, Monday, Oct. 12 Accreditation: none
Monday, October 12 9:00 AM - 5:00 PM Room: Moscone South, Lower Level
The Exhibit Hall is the place to learn, explore, network, and take a break during TCT. More than 120 booths fill the large hall with the latest cutting-edge products and services selected just for you. 9:00 AM - 5:00 PM
9:00 AM Exhibit Hall
Tuesday, October 13, 2015
Main Arena II, Tuesday, Oct. 13 Accreditation: CME/CNE
Tuesday, October 13 8:00 AM - 2:00 PM Room: Moscone South, Esplanade Level, Main Arena
Plenary Session IX. Live Cases 3: Peripheral Vascular Disease 8:00 AM - 9:30 AM Live Case Moderator: John R. Laird Jr Live Case Co-Moderator: Kenneth Rosenfield Live Case Discussants: Owayed Al Shemmari, Gary M. Ansel, J. Michael Bacharach, Jacques Busquet, Gerald Dorros, Hans Krankenberg, Ehtisham Mahmud, Krishna J. Rocha-Singh, Peter A. Schneider, Craig M. Walker, Christopher K. Zarins Digital Moderator: Mahmood K. Razavi Digital Panelists: Narenda N. Khanna, Prakas Chandra Mandal, Alex Powell, Bruno Scheller
8:00 AM Walnut Hill Medical Center, Dallas, TX: PVD Potpourri Live Case Operators: Danny Chan, MD, Tony Das, Tulio Diaz, MD, John H. Rundback, Kenneth Saland, MD, Jaryd Stein, MD
8:45 AM Columbia University Medical Center/NewYork-Presbyterian Hospital, New York, NY: PVD-SFA Live Case Operators: William A. Gray, Philip Green, Anthony L. Pucillo, MD
Plenary Session X. Hot Topics 2: Re-inventing Clinical Research and Patient Care for a New Generation 9:30 AM - 10:05 AM Moderators: Roxana Mehran, Bram D. Zuckerman Digital Moderator: Aaron V. Kaplan Digital Panelists: Lauren S. Baker, Sanjay Kaul, David F. Kong, Frederic S. Resnic Discussant: Jeffrey Shuren
9:30 AM KEYNOTE LECTURE: An FDA Changing Vision for Medical Device Regulation – Innovation, Speed-to-Market, Patient Safety, and Creative Clinical Research Pathways Jeffrey Shuren
9:45 AM KEYNOTE LECTURE: Redefining Clinical Research and Patient Care: The New Era of Big Data, Precision Medicine, and Digital Health Robert A. Harrington 10:00 AM Roundtable Discussion With Audience Q&A
Plenary Session XI. Clinically Oriented Case-Based Tutorials 2: Complex and High-Risk PCI 10:05 AM - 10:45 AM Moderators: Ajay J. Kirtane, E. Magnus Ohman Digital Moderator: Cindy L. Grines Digital Panelists: Adriano Caixeta, Morton J. Kern, Miodrag C. Ostojic, Christian M. Spaulding Discussants: Todd J. Brinton, Michael J. Cowley, Navin K. Kapur, William W. O'Neill, Manesh R. Patel, Harry R. Phillips, Gert Richardt, Habib Samady
10:05 AM CHIP Case: Low EF, CTO, and Calcific MVD Case Presenter: Barry D. Rutherford
10:10 AM CHIP Case: Low EF, CTO, and Calcific MVD – Focused Commentary Holger Thiele
10:15 AM Roundtable Discussion With Audience Q&A
10:25 AM Multivessel PCI in STEMI Case Presenter: Margaret B. McEntegart
10:30 AM Multivessel PCI in STEMI: Focused Commentary Shamir R. Mehta
10:35 AM Roundtable Discussion With Audience Q&A
Plenary Session XII. Young Investigator Award 10:45 AM - 11:00 AM Moderator: Gregg W. Stone
10:45 AM TCT 2015 Thomas J. Linnemeier Spirit of Interventional Cardiology Young Investigator Award Award Presenter: Gregg W. Stone Discussants: Ziad A. Ali, Toby Rogers, Marina Urena
Plenary Session XIII. Late-Breaking Clinical Trials 2: Co-sponsored by The Lancet 11:00 AM - 12:00 PM Moderators: Richard Horton, Stuart Spencer, Gregg W. Stone Digital Moderator: James A. Goldstein Digital Panelists: John A. Ambrose, Ronald Caputo, Jacek Legutko, Bonnie H. Weiner Discussants: David P. Faxon, Anthony H. Gershlick, Jose P.S. Henriques, Alice K. Jacobs, Stefan K. James, Sanjit S. Jolly, Kenneth W. Mahaffey, Holger Thiele, Giora Weisz
11:00 AM RIVER-PCI: A Prospective, Double-blind, Placebo-Controlled Randomized Trial of Ranolazine in Patients With Incomplete Revascularization After Coronary Intervention Giora Weisz
11:12 AM Roundtable Discussion With Audience Q&A 11:24 AM EXPLORE: A Prospective Randomized Trial of Chronic Total Occlusion Intervention Versus Medical Therapy After Successful Primary Angioplasty in Patients With ST- Segment Elevation Myocardial Infarction Jose P.S. Henriques
11:34 AM Roundtable Discussion With Audience Q&A
11:42 AM TOTAL: A Prospective Randomized Trial of Thrombus Aspiration in Patients With ST- Segment Elevation Myocardial Infarction – One-Year Outcomes Sanjit S. Jolly
11:52 AM Roundtable Discussion With Audience Q&A
Plenary Session XIV. First Report Investigations 2 12:00 PM - 12:30 PM Moderators: Daniel S. Berman, Holger Thiele Digital Moderator: Giuseppe Biondi-Zoccai Digital Panelists: Colin Berry, Elmir Omerovic, Guido Parodi Discussants: Jeroen J. Bax, James C. Blankenship, Eric Boersma, Giuseppe De Luca, Steffen Desch, Pamela S. Douglas, Dietmar H. Glogar, Mark Andrew Hlatky, Massimo Napodano, Michel Ovize, Enrico Romagnoli
12:00 PM A Prospective Randomized Trial of Thrombus Aspiration in Patients With ST-Segment Elevation Myocardial Infarction Presenting Late After Symptom Onset Steffen Desch
12:08 PM Roundtable Discussion With Audience Q&A
12:15 PM PLATFORM: Quality-of-Life and Economic Outcomes of an FFR-CT Diagnostic Strategy in Patients With Suspected Coronary Artery Disease Mark Andrew Hlatky
12:23 PM Roundtable Discussion With Audience Q&A
Plenary Session XV. Live Cases 4: Left Atrial Appendage Closure 12:30 PM - 2:00 PM Live Case Moderator: Martin B. Leon Live Case Co-Moderator: Horst Sievert Live Case Discussants: Krzysztof Bartus, Sergio Berti, Stefan C. Bertog, David P. Foley, David Hildick- Smith, Randall J. Lee, Brij Maini, David Meerkin, Peter B Sick, Lars Sondergaard, Nina C. Wunderlich Digital Moderator: Ramon Quesada Digital Panelists: Steven L. Almany, Steven L. Goldberg, Petr Neuzil, Bushra S Rana
12:30 PM Columbia University Medical Center/NewYork-Presbyterian Hospital, New York, NY Live Case Operators: William A. Gray, Philip Green, Omar K. Khalique, Robert J. Sommer
1:15 PM University of Washington Medical Center/Regional Heart Center, Seattle, WA Live Case Operators: Thomas Jones, MD, G. Burkhard Mackensen, Elizabeth M Perpetua, Mark Reisman Coronary Theater II, Tuesday, Oct. 13 Accreditation: CME/CNE
Tuesday, October 13 8:00 AM - 12:00 PM Room: Moscone North, Lower Level, Hall D
Session I. Live Cases: Chronic Total Occlusions 8:00 AM - 10:00 AM Live Case Moderator: David E. Kandzari Live Case Co-Moderator: Truls Råmunddal Live Case Discussants: David Antoniucci, Yasushi Asakura, Christopher E. Buller, Haim Danenberg, Tony J. DeMartini, Alfredo R. Galassi, Scott Harding, Paul Hsien-Li Kao, Masahisa Yamane Digital Moderator: Mauro Carlino Digital Panelists: Robert T Gerber, Gabor Sutsch, Barry F. Uretsky
8:00 AM Columbia University Medical Center, New York, NY Live Case Operators: Michael B. Collins, Dimitri Karmpaliotis, Akiko Maehara, Jeffrey W. Moses, Manish A. Parikh
9:00 AM University of Washington Medical Center/Regional Heart Center, Seattle, WA Live Case Operators: Creighton W. Don, William L. Lombardi, William Nicholson
Session II. Live Cases: Chronic Total Occlusions 10:00 AM - 12:00 PM Live Case Moderator: J. Aaron Grantham Live Case Co-Moderator: Masahiko Ochiai Live Case Discussants: Yuji Ikari, Sunao Nakamura, Goran K. Olivecrona, Ashish Pershad, Sudhir Rathore, Stéphane Rinfret, Georgios Sianos, Satoru Sumitsuji, R. Michael Wyman Digital Moderator: Gerald S. Werner Digital Panelists: Young-Hak Kim, Jacques J. Koolen, Hadley K. Wilson, Jochen Wöhrle
10:00 AM Columbia University Medical Center, New York, NY Live Case Operators: Michael B. Collins, Dimitri Karmpaliotis, Akiko Maehara, Jeffrey W. Moses, Manish A. Parikh
11:00 AM University of Washington Medical Center/Regional Heart Center, Seattle, WA Live Case Operators: Creighton Don, William L. Lombardi, William Nicholson
Endovascular Theater I, Tuesday, Oct. 13 Accreditation: CME/CNE Tuesday, October 13 8:00 AM - 12:00 PM Room: Moscone North, Lower Level, Hall D
Session I. Live Cases: Lower-Extremity Interventions 8:00 AM - 10:00 AM Live Case Moderator: Thomas Zeller Live Case Co-Moderator: Lawrence A. Garcia Live Case Discussants: J. Dawn Abbott, Ehrin J. Armstrong, Giuseppe Biondi-Zoccai, Eric J. Dippel, Roger Gammon, Zaza Kavteladze, Thosaphol Limpijankit, Christopher D. Owens, David P. Slovut Digital Moderator: George L Adams Digital Panelists: Mark J. Goodwin, Luis A. Guzman, Francesco Liistro, Ravish Sachar
8:00 AM Wellmont Holston Valley Hospital, Kingsport, TN Live Case Operators: Mark Aziz, MD, D. Christopher Metzger, Rahul Sakhuja
9:00 AM Walnut Hill Medical Center, Dallas, TX Live Case Operators: Tony Das, Julio Diaz, MD, John H. Rundback, Kenneth Saland, MD
Session II. Live Cases: Lower-Extremity Interventions 10:00 AM - 12:00 PM Live Case Moderator: J. A. Mustapha Live Case Co-Moderator: Mahmood K. Razavi Live Case Discussants: Mark C. Bates, Sriram S. Iyer, R. Stefan Kiesz, Robert A. Lookstein, Thomas O. McNamara, Sahil A. Parikh, Alex Powell, Andrej Schmidt, Rajesh V Swaminathan Digital Moderator: Peter A. Schneider Digital Panelists: Krishna J. Rocha-Singh, Zoltan Ruzsa, Michael H. Wholey, James P. Zidar
10:00 AM Wellmont Holston Valley Hospital, Kingsport, TN Live Case Operators: Mark Aziz, D. Christopher Metzger, Rahul Sakhuja
11:00 AM Walnut Hill Medical Center, Dallas, TX Live Case Operators: Tony Das, Julio Diaz, MD, John H. Rundback, Kenneth Saland, MD
TCT 2015 Exhibit Hall, Tuesday, Oct. 13 Accreditation: none
Tuesday, October 13 9:00 AM - 5:00 PM Room: Moscone South, Lower Level
The Exhibit Hall is the place to learn, explore, network, and take a break during TCT. More than 120 booths fill the large hall with the latest cutting-edge products and services selected just for you. 9:00 AM - 5:00 PM
9:00 AM Exhibit Hall Cath Lab Radiation Hazards: Managing Patient, Operator, and Staff Risks, Part 2 Accreditation: CME/CNE
Tuesday, October 13 1:00 PM - 2:00 PM Room: Moscone South, Lower Level, Room 103
Cath Lab Radiation Hazards: Managing Patient, Operator, and Staff Risks, Part 2 1:00 PM - 2:00 PM Moderators: Stephen Balter, Edwin M. Leidholdt, Jr.
1:00 PM Advanced Patient Radiation Management (eg, Follow-up) Stephen Balter, Edwin M. Leidholdt, Jr.
1:10 PM Staff Radiation Protection Stephen Balter, Edwin M. Leidholdt, Jr.
1:25 PM Quality Processes (Includes NCRP S11) Stephen Balter, Edwin M. Leidholdt, Jr.
1:40 PM Post-test Stephen Balter, Edwin M. Leidholdt, Jr.
1:50 PM Roundtable Discussion With Audience Q&A
Controversies in Interventional Cardiology: The Skeptic’s Corner, Part 2 Accreditation: CME/CNE
Tuesday, October 13 1:00 PM - 2:00 PM Room: Moscone South, Lower Level, Room 102
Elective PCI Issues: We’re Skeptical! 1:00 PM - 2:00 PM Moderators: Eric R. Bates, Spencer B. King III Discussants: David J. Cohen, Sanjay Kaul, Issam D. Moussa, Simon Redwood, Frederic S. Resnic, Daniel I. Simon
1:00 PM I Don’t Believe DAPT Should Be Discontinued at or Before 12 Months After Elective DES Implantation! Daniel I. Simon
1:10 PM Roundtable Discussion With Audience Q&A 1:20 PM I Don’t Believe That Public Reporting Improves Clinical Outcomes! Frederic S. Resnic
1:30 PM Roundtable Discussion With Audience Q&A
1:40 PM I Believe That Most PCI Procedures for Stable CAD Are NOT Worth the Time/Effort/Risk/Money! Sanjay Kaul
1:50 PM Roundtable Discussion With Audience Q&A
Coronary Drug-Coated Balloons: Devices, Applications, and Emerging Data Accreditation: CME/CNE
Tuesday, October 13 1:00 PM - 2:00 PM Room: Moscone North, Lower Level, Room 132
Coronary Drug-Coated Balloons: Devices, Applications, and Emerging Data 1:00 PM - 2:00 PM Moderators: Juan F. Granada, Bruno Scheller Discussants: Fernando Alfonso, Robert A. Byrne, Germano Di Sciascio, Yukio Ozaki, Dinesh Shah, Pieter R. Stella
1:00 PM The Promise of Vascular Restoration Therapy for De Novo Lesions: Technique, Limitations, and Clinical Data Bruno Scheller
1:12 PM Roundtable Discussion With Audience Q&A
1:17 PM DCB for ISR Treatment: Technical Considerations for Optimization of Clinical Outcomes Pieter R. Stella
1:29 PM Life After the RIBS Trials: A Critical Overview of the Data and Implications for Clinical Practice Fernando Alfonso
1:39 PM Roundtable Discussion With Audience Q&A
1:44 PM The Technological Evolution of Local Drug Delivery: Implications for the Clinical Adoption of Coronary DCBs Juan F. Granada
1:56 PM Roundtable Discussion With Audience Q&A Fellows Session: ACS and Pharmacotherapy Year-in-Review Accreditation: CME/CNE
Tuesday, October 13 1:00 PM - 2:00 PM Room: Moscone North, Lower Level, Room 133
Fellows Session: ACS and Pharmacotherapy Year-in-Review 1:00 PM - 2:00 PM Moderators: George D. Dangas, Paul A. Gurbel Discussants: John A. Ambrose, Bill J. French, C. Michael Gibson, Robert A. Harrington, Joshua W. Knowles, Duane S. Pinto, Marco Valgimigli
1:00 PM The MATRIX of Antithrombin Alternatives: Pros and Cons Marco Valgimigli
1:07 PM Roundtable Discussion With Audience Q&A
1:10 PM Intravenous P2Y12 Inhibition: Role for Cangrelor Robert A. Harrington
1:17 PM Roundtable Discussion With Audience Q&A
1:20 PM Acute DAPT Decisions: Agent Selection and Whether to Load Paul A. Gurbel
1:27 PM Roundtable Discussion With Audience Q&A
1:30 PM Optimal DAPT Duration After DES Somjot S. Brar
1:37 PM Roundtable Discussion With Audience Q&A
1:40 PM PCI and Atrial Fibrillation Anticoagulation: Triple or Dual Therapy? C. Michael Gibson
1:47 PM Roundtable Discussion With Audience Q&A
1:50 PM Hyperlipidemic Therapy: From Statins to PCSK9 Inhibitors Joshua W. Knowles
1:57 PM Roundtable Discussion With Audience Q&A
Interventional and Surgical Management of Functional MR: Case Studies in Conflict and Consensus (Co-sponsored by AATS) Accreditation: CME
Tuesday, October 13 1:00 PM - 2:00 PM Room: Moscone North, Lower Level, Room 130 Interventional and Surgical Management of Functional MR: Case Studies in Conflict and Consensus 1:00 PM - 2:00 PM Moderator: Michael A. Borger Discussants: Isaac George, Marc Gillinov, David R. Holmes Jr., Michael J. Mack, Igor F. Palacios, Allan Schwartz
1:00 PM Case Presentation: Introduction Case Presenter: Jonathan M. White
1:05 PM CTSNet Ischemic MR Trial: Implications for Patient Management Vinod H. Thourani
1:15 PM MV Repair: At What Risk for What Benefit? Marc Gillinov
1:25 PM MitraClip and Transcatheter Annuloplasty for Functional MR: How Effective? Gorav Ailawadi
1:35 PM Percutaneous MV Replacement: The Future Is (Almost) Now Wesley R. Pedersen
1:45 PM Case Presentation: Resolution Case Presenter: Jonathan M. White
1:50 PM Roundtable Discussion With Audience Q&A
Secondary Prevention After PCI (Today and Tomorrow): Guideline Therapies, Ranolazine, and PCSK9 Inhibitors Accreditation: CME/CNE
Tuesday, October 13 1:00 PM - 2:00 PM Room: Moscone North, Lower Level, Room 131
Secondary Prevention After PCI (Today and Tomorrow): Guideline Therapies, Ranolazine, and PCSK9 Inhibitors 1:00 PM - 2:00 PM Moderators: Bernard J. Gersh, Stephen D. Wiviott Discussants: Ori Ben-Yehuda, Michael E. Farkouh, Mark Goldberger, David J. Maron, Evan A. Stein, Giora Weisz
1:00 PM Optimal Medical Therapy After PCI: What Is Optimal, and What Is Realistic? David J. Maron
1:12 PM PCSK9: Effects on LDL and Emerging Data on Cardiovascular Events Evan A. Stein
1:24 PM Non-LDL Lowering Agents: Trials and Tribulations of HDL, Triglycerides, and Lp-PLA2 – What Hasn’t Worked, and Why? Stephen D. Wiviott
1:36 PM Adjuvant Pharmacotherapy With Ranolazine In Patients With Ischemic Heart Disease Giora Weisz
1:48 PM Roundtable Discussion With Audience Q&A
Adult Congenital Heart Disease Intervention Accreditation: CME/CNE
Tuesday, October 13 1:00 PM - 2:00 PM Room: Moscone North, Lower Level, Room 123
Adult Congenital Heart Disease Intervention 1:00 PM - 2:00 PM Moderators: Ziyad M. Hijazi, John F. Rhodes Discussants: Elchanan Bruckheimer, Doff B. McElhinney
1:00 PM Patent Ductus Arteriosus Closure in the Adult: Guidelines for Management and Technical Considerations Doff B. McElhinney
1:12 PM Two Illustrative Cases of PDA Closure: One Simple and One Large and Complex Case Presenter: Lee N. Benson
1:24 PM Roundtable Discussion With Audience Q&A
1:30 PM Coarctation of the Aorta in the Adult Patient: Guidelines for Management and Technical Considerations Clifford J. Kavinsky
1:42 PM Two Illustrative Cases: One Simple Coarctation Without Complications and One Complex Coarctation With Complications Case Presenter: Elchanan Bruckheimer
1:56 PM Roundtable Discussion With Audience Q&A
Basics of Neurointervention Accreditation: CME/CNE Tuesday, October 13 1:00 PM - 2:00 PM Room: Moscone North, Lower Level, Room 125
Basics of Neurointervention 1:00 PM - 2:00 PM Moderator: Leo Nelson Hopkins Discussants: Alex Abou-Chebl, Gary S. Roubin, Adnan Siddiqui
1:00 PM Safe Arch Access and Creation of a Stable Carotid and Vertebral Platform (With Case Examples) Case Presenter: Gary S. Roubin
1:08 PM Roundtable Discussion With Audience Q&A
1:12 PM Tools and Techniques for Benign Passage Through the Skull Base to the Intracranial Circulation (With Case Examples) Adnan Siddiqui
1:20 PM Roundtable Discussion With Audience Q&A
1:24 PM Tools and Techniques for Safe Intracranial Angioplasty and Stenting (With Case Examples) Case Presenter: Leo Nelson Hopkins
1:32 PM Roundtable Discussion With Audience Q&A
1:36 PM Intracranial Clot Removal: “Stentriever” Tools and Techniques (With Case Examples) Case Presenter: Adnan Siddiqui
1:44 PM Roundtable Discussion With Audience Q&A
1:48 PM When to Intervene: Imaging Guide to Stroke Intervention (With Case Examples) Case Presenter: Alex Abou-Chebl
1:56 PM Roundtable Discussion With Audience Q&A
Complex Bifurcations (Organized by the European Bifurcation Club) Accreditation: CME/CNE
Tuesday, October 13 1:00 PM - 2:00 PM Room: Moscone North, Lower Level, Room 124
Complex Bifurcations 1:00 PM - 2:00 PM Moderator: Goran Stankovic Discussants: Remo Albiero, Shao-Liang Chen, Bernard R. Chevalier 1:00 PM When and How to: Use a Provisional Approach in Complex Bifurcations (With Case Examples) Case Presenter: Bernard R. Chevalier
1:12 PM Roundtable Discussion With Audience Q&A
1:15 PM When and How to: Perform TAP Stenting in Complex Bifurcations (Step-by-Step, With Case Examples) Case Presenter: Remo Albiero
1:27 PM Roundtable Discussion With Audience Q&A
1:30 PM When and How to: Perform Culotte Stenting in Complex Bifurcations (Step-by-Step, With Case Examples) Case Presenter: Goran Stankovic
1:42 PM Roundtable Discussion With Audience Q&A
1:45 PM When and How to: Perform DK Crush Stenting in Complex Bifurcations (Step-by-Step, With Case Examples) Case Presenter: Shao-Liang Chen
1:57 PM Roundtable Discussion With Audience Q&A
LAA Occlusion Tips and Tricks Accreditation: CME/CNE
Tuesday, October 13 1:00 PM - 2:00 PM Room: Moscone North, Lower Level, Room 122
Session I. LAA Closure With the Watchman Device 1:00 PM - 1:30 PM Moderators: Maurice Buchbinder, Zoltan G. Turi Discussants: Shephal Doshi, Jan Kovac, Matthew J. Price, Steven J. Yakubov
1:00 PM Preprocedural Planning for the Watchman Device: Case Examples Shephal Doshi
1:10 PM Watchman Procedure Step-by-Step Case Presenter: Maurice Buchbinder
1:20 PM Complex LAA Closure With Watchman Case Presenter: Matthew J. Price
1:25 PM Procedural Complications With Watchman: Case Examples Michael J. Rinaldi Session II. Amplatzer Cardiac Plug and Lariat 1:30 PM - 2:00 PM Moderator: Zoltan G. Turi Discussants: Shephal Doshi, Jan Kovac, Matthew J. Price, Steven J. Yakubov
1:30 PM Lariat Procedure Step-by-Step Case Presenter: Steven J. Yakubov
1:40 PM ACP Procedure Step-by-Step Case Presenter: Giuseppe Tarantini
1:50 PM Roundtable Discussion With Audience Q&A
Nuts and Bolts of IVUS and NIRS Imaging Accreditation: CME/CNE
Tuesday, October 13 1:00 PM - 2:00 PM Room: Moscone North, Lower Level, Room 120
Nuts and Bolts of IVUS and NIRS Imaging 1:00 PM - 2:00 PM Moderators: Ryan D. Madder, Gary S. Mintz Discussants: David Erlinge, Ning Guo, Soo-Jin Kang, Margaret B. McEntegart
1:00 PM Case 1: IVUS Guidance of a Challenging Left Main PCI Case Presenter: Ning Guo
1:10 PM Case 2: IVUS Guidance for a Calcified Lesion Case Presenter: Margaret B. McEntegart
1:20 PM Case 3: NIRS for Prediction of Future Events (Vulnerable Plaque) Case Presenter: Ryan D. Madder
1:30 PM Case 4: NIRS in Acute Coronary Syndrome – Recognition and Treatment of Neoatherosclerosis Case Presenter: David Erlinge
1:40 PM My Top 5 Uses for IVUS Diagnosis and Procedural Guidance Gary S. Mintz
1:50 PM Top 5 Uses for NIRS Diagnosis and Procedural Guidance Soo-Jin Kang Transseptal Puncture Accreditation: CME/CNE
Tuesday, October 13 1:00 PM - 2:00 PM Room: Moscone North, Lower Level, Room 121
Transseptal Puncture 1:00 PM - 2:00 PM Moderators: Ted E. Feldman, Samir R. Kapadia, Saibal Kar Discussants: Howard C. Herrmann, Ziyad M. Hijazi, Brian K. Whisenant
1:00 PM The Basic Transseptal Puncture Step-by-Step Ted E. Feldman
1:10 PM The Difficult Transseptal Puncture Step-by-Step Samir R. Kapadia
1:20 PM Complications of Transseptal Puncture: Recognition and Management Ziyad M. Hijazi
1:30 PM Case 1: Transseptal Puncture With MitraClip Case Presenter: Howard C. Herrmann
1:36 PM Discussion With Audience Q&A
1:40 PM Case 2: Transseptal Puncture for Left Atrial Appendage Closure Case Presenter: Brian K. Whisenant
1:46 PM Discussion With Audience Q&A
1:50 PM Case 3: Overcoming Challenging Venous Anatomy – Stepwise Approach Case Presenter: Saibal Kar
1:56 PM Discussion With Audience Q&A
Acute Coronary Syndrome and Acute Myocardial Infarction Accreditation: CME/CNE
Tuesday, October 13 2:00 PM - 4:15 PM Room: Moscone West, 2nd Floor, Room 2006 - 2008
Acute Coronary Syndrome and Acute Myocardial Infarction 2:00 PM - 4:15 PM Moderators: Eric Boersma, Richard Smalling Discussants: Andrea Abizaid, Giuseppe De Luca, Larry S. Dean, Peter L Duffy, Jeff Marshall, Robert L. Wilensky 2:00 PM TCT 1: High Number of Angiographic Significant Lesions Are FFR Negative in STEMI Patients With Multivessel Disease – Preliminary Insight Into the COMPARE-ACUTE Trial Pieter C. Smits
2:10 PM Roundtable Discussion With Audience Q&A
2:15 PM TCT 2: Early or Late Intervention in Patients With Transient ST-Segment Elevation Acute Coronary Syndrome – Subgroup Analysis of the ELISA-3 Trial Erik Badings
2:25 PM Roundtable Discussion With Audience Q&A
2:30 PM TCT 3: Thrombus Aspiration in Patients With Large Anterior Myocardial Infarction – A TASTE Trial Substudy Fredrik Calais
2:40 PM Roundtable Discussion With Audience Q&A
2:45 PM TCT 4: Spontaneous Coronary Artery Dissection in Women and Association With Hormonal Stressors Eng Lim
2:55 PM Roundtable Discussion With Audience Q&A
3:00 PM TCT 5: Timing for Transcatheter Closure of Ventricular Septal Rupture After Acute Myocardial Infarction Geng Qian
3:10 PM Roundtable Discussion With Audience Q&A
3:15 PM TCT 6: Five-Year Optical Coherence Tomography of Patients With ST-Elevation Myocardial Infarction Treated With Bare-Metal Versus Everolimus-Eluting Stents (the RE-EXAMINATION Study) Josep Gomez Lara
3:25 PM Roundtable Discussion With Audience Q&A
3:30 PM TCT 7: Trends and Outcomes of Percutaneous Coronary Intervention for Ventricular Tachycardia or Fibrillation Cardiac Arrest – Analysis From Nationwide Inpatient Sample Nish Patel
3:40 PM Roundtable Discussion With Audience Q&A
3:45 PM TCT 8: First Results of the EXPLORE Trial – A Global, Randomized, Prospective, Multicenter Trial Investigating the Impact of Recanalization of a Chronic Total Occlusion on Left Ventricular Function in Patients After Primary Percutaneous Coronary Intervent Jose P.S. Henriques
3:55 PM Roundtable Discussion With Audience Q&A
4:00 PM TCT 9: Early PICSO Preserves LVEF in Porcine Acute Myocardial Infarction Roger Kessels 4:10 PM Roundtable Discussion With Audience Q&A
Bioresorbable Vascular Scaffolds Accreditation: CME/CNE
Tuesday, October 13 2:00 PM - 4:00 PM Room: Moscone West, 2nd Floor, Room 2010
Bioresorbable Vascular Scaffolds 2:00 PM - 4:00 PM Moderators: Stephen G. Ellis, Lorenz Raber Discussants: Roberto Botelho, Lisette Okkels Jensen, Vincent On-Hing Kwok, Detlef G. Mathey, Massimo Napodano, Robert C. Welsh
2:00 PM TCT 10: Clinical Outcomes Following "Full-Plastic Jacket" – Bioresorbable Scaffold Implantation Hiroyoshi Kawamoto
2:10 PM Roundtable Discussion With Audience Q&A
2:15 PM TCT 11: Five-year Follow-up of the First-in-Man Use of a Polylactide Bioresorbable Scaffold Eluting Everolimus for Treatment of Coronary Stenosis: A Serial Multi- Imaging Modality Study Patrick W. Serruys
2:25 PM Roundtable Discussion With Audience Q&A
2:30 PM TCT 12: Impact of Overlap on Long-term Clinical Outcomes in Patients Undergoing Everolimus-Eluting Bioresorbable Vascular Scaffolds Implantation in Routine Clinical Practice – Insights From the European Multicenter GHOST-EU Registry Luis Ortega-Paz
2:40 PM Roundtable Discussion With Audience Q&A
2:45 PM TCT 13: Clinical Outcomes After Implantation of Absorb BVS in Small Vessels – Results From the Italian RAI Multicenter Registry Giulia Masiero
2:55 PM Roundtable Discussion With Audience Q&A
3:00 PM TCT 14: ABSORB FIRST – One-Year Clinical Outcomes From a Prospective, Multicenter, Global, Real-world Registry Ashok Seth
3:10 PM Roundtable Discussion With Audience Q&A
3:15 PM TCT 15: Multislice Computed Tomography Assessment of Absorb Bioresorbable Vascular Scaffold in Comparison With Metallic Drug-Eluting Stents – Data From the ABSORB Japan Trial Kengo Tanabe
3:25 PM Roundtable Discussion With Audience Q&A
3:30 PM TCT 16: Do Overlapping Scaffolds Have an Impact on Clinical Outcome? Analysis of the ABSORB-EXTEND Single-Arm Study Pieter C. Smits
3:40 PM Roundtable Discussion With Audience Q&A
3:45 PM TCT 17: Prospective, Multicenter Evaluation of the DESolve Novolimus-Eluting Bioresorbable Coronary Scaffold – Imaging Outcomes and 3-Year Clinical and Imaging Results Alexandre Abizaid
3:55 PM Roundtable Discussion With Audience Q&A
Complex and High-Risk Intervention (CHIP) Accreditation: CME/CNE
Tuesday, October 13 2:00 PM - 4:00 PM Room: Moscone West, 2nd Floor, Room 2012
Complex and High-Risk Intervention (CHIP) 2:00 PM - 4:00 PM Moderators: Eric A. Cohen, Truls Råmunddal Discussants: Stuart J. Head, Angela Hoye, Petr Kala, Sreenivas Arramraju Kumar, Hadley K. Wilson
2:00 PM TCT 18: Impact of Incomplete Revascularization After Percutaneous Coronary Intervention as Assessed by the SYNTAX Revascularization Index in Complex Coronary Artery Disease – A SEEDS Substudy Nicolas Bettingeer
2:10 PM Roundtable Discussion With Audience Q&A
2:15 PM TCT 19: Two-Year Clinical Outcomes and Chest Pain in 1,811 All-Comer Patients, Treated for Bifurcated Versus Nonbifurcated Lesions With Highly Deliverable Drug- Eluting Coronary Stents Liefke van der Heijden
2:25 PM Roundtable Discussion With Audience Q&A
2:30 PM TCT 20: Use of a Percutaneous Left Ventricular Assist Device for High-Risk Percutaneous Coronary Interventions – Clinical Trial Versus Real-World Experience Mauricio G. Cohen
2:40 PM Roundtable Discussion With Audience Q&A
2:45 PM TCT 21: Guidewire and Microcatheter Utilization for Antegrade Wire Escalation in Chronic Total Occlusion Percutaneous Coronary Intervention – Insights From a Contemporary Multicenter Registry Muhammad Nauman Tarar
2:55 PM Roundtable Discussion With Audience Q&A
3:00 PM TCT 22: Patent and Occluded Saphenous Vein Grafts as Retrograde Conduits for Percutaneous Revascularization of Coronary Chronic Total Occlusions: The Quebec Experience Rustem Dautov
3:10 PM Roundtable Discussion With Audience Q&A
3:15 PM TCT 23: Patients, Lesion Characteristics, and Procedural Outcome Against Interventional Revascularization on Chronic Total Occlusion of Prior Coronary Artery Bypass Graft Surgery Masaki Tanabe
3:25 PM Roundtable Discussion With Audience Q&A
3:30 PM TCT 24: Selection of Collateral Channel Guided by a Hierarchic Decision Algorithm Achieved High Technical Success Rate and Low Procedural Complication Rate in Real-world Retrograde Percutaneous Coronary Intervention (PCI) for Chronic Total Occlusion (CTO) Ching-Chang Huang
3:40 PM Roundtable Discussion With Audience Q&A
3:45 PM TCT 25: Randomized Comparison of Final Kissing Balloon Dilatation Versus No Final Kissing Balloon Dilatation in Patients With Coronary Bifurcation Lesions Treated With Main Vessel Stenting – Five-Year Clinical Outcomes in the Nordic-Baltic Bifurcation Stu Matti Jaakko Niemela
3:55 PM Roundtable Discussion With Audience Q&A
Congenital Heart Disease and Other Structural Interventions Accreditation: CME/CNE
Tuesday, October 13 2:00 PM - 4:15 PM Room: Moscone West, 2nd Floor, Room 2014 - 2018
Congenital Heart Disease and Other Structural Interventions 2:00 PM - 4:15 PM Moderators: John P. Cheatham, Carlos Pedra Discussants: Lee N. Benson, Adnan K. Chhatriwalla, Eulogio J. Garcia, Paul H. Kramer, Eustaquio Maria Onorato, Robert J. de Winter
2:00 PM TCT 26: Balloon Pulmonary Angioplasty Driven by Combined Assessment of Intraarterial Anatomy and Physiology in Patients With Nonoperable Distal Chronic Thromboembolic Pulmonary Hypertension Marek Roik
2:10 PM Roundtable Discussion With Audience Q&A
2:15 PM TCT 27: Impact of Primary Stenting Compared to Balloon Dilatation Alone on Pulmonary Vein Restenosis R. Jay Widmer
2:25 PM Roundtable Discussion With Audience Q&A
2:30 PM TCT 28: Treat and Repair Strategies for Adult Patients With Atrial Septal Defect and Severe Pulmonary Atrial Hypertension Teiji Akagi
2:40 PM Roundtable Discussion With Audience Q&A
2:45 PM TCT 29: Safety and Efficacy of Percutaneous Device Closure of Large Posttricuspid Shunts in Pediatric Patients With Severe PAH at Short-term and Midterm Follow-up Jayal Shah
2:55 PM Roundtable Discussion With Audience Q&A
3:00 PM TCT 30: PREMIUM Trial – Double-blind Study of Percutaneous Closure of Patent Foramen Ovale With the AMPLATZER PFO Occluder as a Treatment for Migraine With or Without Aura Jonathan M. Tobis
3:10 PM Roundtable Discussion With Audience Q&A
3:15 PM TCT 31: Immediate and 1-Year US IDE Trial Results of the New GORE CARDIOFORM Septal Occluder for Transcatheter Closure of Secundum Atrial Septal Defects Joseph Paolillo
3:25 PM Roundtable Discussion With Audience Q&A
3:30 PM TCT 32: Percutaneous Ventricular Restoration (PVR) Therapy Using the Parachute Device in Patients With Ischemic Dilated Heart Failure – Two-Year Results of the PARACHUTE III European Postmarket Trial Ulrich Schaefer
3:40 PM Roundtable Discussion With Audience Q&A
3:45 PM TCT 33: Left Atrial Decompression With the V-Wave Shunt Device for the Treatment of Heart Failure – Preliminary Safety and Efficacy Results Maria Del Trigo
3:55 PM Roundtable Discussion With Audience Q&A
4:00 PM TCT 34: Completeness of Defect Closure Determined the Resolution of Hemolytic Anemia in Patients Undergoing Transcatheter Paravalvular Leak Closure Grzegorz Smolka
4:10 PM Roundtable Discussion With Audience Q&A FFR and Physiologic Lesion Assessment Accreditation: CME/CNE
Tuesday, October 13 2:00 PM - 4:00 PM Room: Moscone West, 2nd Floor, Room 2002 - 2004
FFR and Physiologic Lesion Assessment 2:00 PM - 4:00 PM Moderators: Javier Escaned, Johan HC Reiber Discussants: Olivier F. Bertrand, Michalis Hamilos, Eugenia Nikolsky, Jan J. Piek, Bruce Samuels, Mladen I. Vidovich
2:00 PM TCT 35: FFR Gray Zone and Clinical Outcome Julien Adjedj
2:10 PM Roundtable Discussion With Audience Q&A
2:15 PM TCT 36: Quantification of the Effect of Measurement Drift on the Diagnostic Performance of FFR, iFR, and Whole Cycle Pd/Pa Christopher Cook
2:25 PM Roundtable Discussion With Audience Q&A
2:30 PM TCT 37: The Prognostic Value of the Residual SYNTAX Score After "Functionally" Complete Revascularization – Insights From the FAME (Fractional Flow Reserve Versus Angiography for Multivessel Evaluation) Trial Yuhei Kobayashi
2:40 PM Roundtable Discussion With Audience Q&A
2:45 PM TCT 38: Long-term Clinical Outcome of Resting Pd/Pa Versus FFR-Guided Deferral of Revascularization Gilbert Wijntjens
2:55 PM Roundtable Discussion With Audience Q&A
3:00 PM TCT 39: Diagnostic Ability of Contrast Medium–Induced Fractional Flow Reserve to Assess Functional Lesion Severity of Coronary Artery Stenosis Hiroaki Takashima
3:10 PM Roundtable Discussion With Audience Q&A
3:15 PM TCT 40: Image-Based Computation of Instantaneous Wave-Free Ratio From Routine Coronary Angiography – Initial Validation by Invasively Measured Coronary Pressures Puneet Sharma
3:25 PM Roundtable Discussion With Audience Q&A
3:30 PM TCT 41: Invasive Assessment of Coronary Flow Reserve in Severe Aortic Stenosis With Normal Coronary Arteries Alejandro Gutierrez-Barrios 3:40 PM Roundtable Discussion With Audience Q&A
3:45 PM TCT 42: Accounting for Right Atrial Pressure in the Calculation of Fractional Flow Reserve (FFR) Significantly Increases the Number of Physiologically Significant Stenoses Suitable for PCI Christopher Cook
3:55 PM Roundtable Discussion With Audience Q&A
Intravascular Imaging Accreditation: CME/CNE
Tuesday, October 13 2:00 PM - 4:00 PM Room: Moscone West, 3rd Floor, Room 3002 - 3004
Intravascular Imaging 2:00 PM - 4:00 PM Moderators: Stephan Achenbach, Marc D. Feldman Discussants: James A. Goldstein, Takashi Kubo, Robert J. Russo, Elias Sanidas, Robert M. Schainfeld, Antonius F.W. van der Steen
2:00 PM TCT 43: Mechanical Abnormalities Associated With Drug-Eluting Stent Thrombosis Analyzed by Optical Coherence Tomography in the National PESTO French Registry Nicolas Amabile
2:10 PM Roundtable Discussion With Audience Q&A
2:15 PM TCT 44: The Impact of Plaque Morphology and Malapposition Area on Late-Phase Stent Malapposition – Insight From the Optimal Coherence Tomography Substudy in PRASFIT Elective Kenzo Uzu
2:25 PM Roundtable Discussion With Audience Q&A
2:30 PM TCT 45: Optical Coherence Tomography Assessment of Incidence, Morphological Characteristics, and Spontaneous Healing Course of Edge Dissections Following Percutaneous Coronary Intervention with Stent Implantation in Patients with Non-ST segment Elevation Lisbeth Antonsen
2:40 PM Roundtable Discussion With Audience Q&A
2:45 PM TCT 46: OCT-Based Management of Late-Stent Thrombosis – Results From the SAFE Registry Catalin Toma
2:55 PM Roundtable Discussion With Audience Q&A 3:00 PM TCT 47: Comparative Optical Coherent Tomographic Analysis of In-Stent Neoatherosclerosis Between First- and Second-Generation Drug-Eluting Stents Mineok Chang
3:10 PM Roundtable Discussion With Audience Q&A
3:15 PM TCT 48: Early Vascular Responses to Everolimus-Eluting Cobalt-Chromium Stent for the Treatment of Stable Coronary Artery Disease – The Results of MECHANISM Elective 1-Month OCT Follow-up Cohort Toshiro Shinke
3:25 PM Roundtable Discussion With Audience Q&A
3:30 PM TCT 49: Underlying Stenosis Severity Is Independent of Culprit Plaque Morphology in STEMI – An Optical Coherence Tomography Study Olli A. Kajander
3:40 PM Roundtable Discussion With Audience Q&A
3:45 PM TCT 50: Peri-strut Low-Intensity Area Assessed by Midterm Follow-up Optical Coherence Tomography May Predict Target Lesion Revascularization After Stent Implantation Koji Kuroda
3:55 PM Roundtable Discussion With Audience Q&A
Left Atrial Appendage Closure and Mitral Valve Disease Accreditation: CME/CNE
Tuesday, October 13 2:00 PM - 4:00 PM Room: Moscone West, 3rd Floor, Room 3006 - 3008
Left Atrial Appendage Closure and Mitral Valve Disease 2:00 PM - 4:00 PM Moderators: Jacqueline Saw, Steven J. Yakubov Discussants: Vasilis Babaliaros, Dariusz Dudek, Sameer Gafoor, Mayra Guerrero, Teguh Santoso, Paul Vermeersch
2:00 PM TCT 51: The Tendyne Transcatheter Mitral Valve Implantation (TMVI) Global Feasibility Trial David W.M. Muller
2:10 PM Roundtable Discussion With Audience Q&A
2:15 PM TCT 52: Response of Forward Stroke Volume Predicts Clinical Outcomes and Echocardiographic Changes After Percutaneous Mitral Valve Repair With MitraClip System Shunsuke Kubo 2:25 PM Roundtable Discussion With Audience Q&A
2:30 PM TCT 53: Left Atrial Appendage Occlusion in Patients With Atrial Fibrillation and Intracranial Bleeding – Results From the Amplatzer Cardiac Plug Registry Apostolos Tzikas
2:40 PM Roundtable Discussion With Audience Q&A
2:45 PM TCT 54: A Comparison of Three-dimensional Echocardiography and Computed Tomography in Sizing the D-Shaped Mitral Annulus Before Transcatheter Mitral Valve Implantation George Mak
2:55 PM Roundtable Discussion With Audience Q&A
3:00 PM TCT 55: Comparing Measurements of the Left Atrial Appendage for Percutaneous Closure Between 3 Imaging Modalities – TEE, CTA, and Fluoroscopy Jacqueline Saw
3:10 PM Roundtable Discussion With Audience Q&A
3:15 PM TCT 56: Standardized Algorithm for Ostium Size Assessment in Left Atrial Appendage Occlusion Using Three-dimensional Echocardiography Felix Meincke
3:25 PM Roundtable Discussion With Audience Q&A
3:30 PM TCT 57: A Cost Analysis of Bleed Complications From 2 Stroke Prevention Strategies in Nonvalvular Atrial Fibrillation: Left Atrial Appendage Closure Versus Warfarin Matthew J. Price
3:40 PM Roundtable Discussion With Audience Q&A
3:45 PM TCT 58: Immediate and Long-term Outcomes of Ischemic Versus Nonischemic Functional Mitral Regurgitation in Patients Treated With MitraClip – Insights From the 2011-12 Pilot European Sentinel Registry of Percutaneous Edge-to-Edge Mitral Valve Repair Michele Pighi
3:55 PM Roundtable Discussion With Audience Q&A
PCI Outcomes and Drug-Eluting Stents Accreditation: CME/CNE
Tuesday, October 13 2:00 PM - 4:00 PM Room: Moscone West, 3rd Floor, Room 3014 - 3018
PCI Outcomes and Drug-Eluting Stents 2:00 PM - 4:00 PM Moderators: Sigmund Silber, Philip M. Urban Discussants: Giuseppe Biondi-Zoccai, Edoardo Camenzind, Christopher Irobunda, John C. Messenger, Duk-Woo Park, Bonnie H. Weiner
2:00 PM TCT 59: The Impact of Timing of Ischemic and Hemorrhagic Events on Mortality After DES – The ADAPT-DES study Sorin J. Brener
2:10 PM Roundtable Discussion With Audience Q&A
2:15 PM TCT 60: Long Coronary Lesions Treated With a Bioresorbable-Polymer Drug-Eluting Stent – Experience From eNOBORI Registry Evgeny Kretov
2:25 PM Roundtable Discussion With Audience Q&A
2:30 PM TCT 61: Noninvasive Discrimination of Coronary Chronic Total Occlusion and Subtotal Occlusion by Coronary Computed Tomography Angiography Jin-Ho Choi
2:40 PM Roundtable Discussion With Audience Q&A
2:45 PM TCT 62: Predicting Value of Platelet Reactivity on Bleeding and Major Adverse Cardiac Events in Eastern Asian Percutaneous Coronary Intervention Patients Wenyao Wang
2:55 PM Roundtable Discussion With Audience Q&A
3:00 PM TCT 63: One-Year Results of the REMEDEE Registry – Clinical Outcomes After Deployment of the Abluminal Sirolimus-Coated Bioengineered Stent in a Multicenter, Prospective Postmarket Registry Robert de Winter
3:10 PM Roundtable Discussion With Audience Q&A
3:15 PM TCT 64: Incidence, Predictors, and Impact of Postdischarge Bleeding Compared to Myocardial Infarction After Percutaneous Coronary Intervention Philippe Généreux
3:25 PM Roundtable Discussion With Audience Q&A
3:30 PM TCT 65: Two-Year Outcomes in Real-World Patients Treated With a Thin-Strut, Platinum-Chromium, Everolimus-Eluting Stent in the PROMUS Element Plus US Postapproval Study (PE-Plus PAS) David E. Kandzari
3:40 PM Roundtable Discussion With Audience Q&A
3:45 PM TCT 66: Long-term Clinical Outcomes of Percutaneous Coronary Intervention Using Drug-Eluting Stent for Native Coronary Chronic Total Occlusion Pil Hyung Lee
3:55 PM Roundtable Discussion With Audience Q&A Peripheral Vascular Disease and Stroke Intervention Accreditation: CME/CNE
Tuesday, October 13 2:00 PM - 4:00 PM Room: Moscone West, 3rd Floor, Room 3010
Peripheral Vascular Disease and Stroke Intervention 2:00 PM - 4:00 PM Moderators: Mark C. Bates, Mark H. Wholey Discussants: Nicola Corvaja, Roger Gammon, Michel Camille Henry, Thomas A. Ischinger, Juan C. Parodi, Ivo Petrov
2:00 PM TCT 67: Comparison of Endovascular Aneurysm Repair With Open Surgery for Elective and Ruptured Abdominal Aortic Aneurysm – A Meta-analysis of Randomized Clinical Trials Mohammad Ansari, MD
2:10 PM Roundtable Discussion With Audience Q&A
2:15 PM TCT 68: Safety and Efficacy of Stent Retriever for the Management of Acute Ischemic Stroke Comprehensive – Review and Meta-analysis Konstantinos Marmagkiolis
2:25 PM Roundtable Discussion With Audience Q&A
2:30 PM TCT 69: Impact of Stage 5 Chronic Kidney Disease in Patients Undergoing Percutaneous or Surgical Carotid Artery Revascularization – Insights of the Healthcare Cost and Utilization Project's National Inpatient Sample Fabio Lima
2:40 PM Roundtable Discussion With Audience Q&A
2:45 PM TCT 70: In-Hospital Mortality and Periprocedural Complications of Percutaneous Peripheral Atherectomy of the United States – Influence of Hospital Volume Samir Patel
2:55 PM Roundtable Discussion With Audience Q&A
3:00 PM TCT 71: Safety and Efficacy of Carotid Stenting With Proximal Embolic Protection Through Transradial/Brachial Approach – Results in 60 Consecutive Patients Piero Montorsi
3:10 PM Roundtable Discussion With Audience Q&A
3:15 PM TCT 72: Prevalence and Distribution of Obstructive Pelvic Arterial Lesions by Computed Tomographic Angiography in 476 Patients With Erectile Dysfunction – Implications for Endovascular Therapy Tzung-Dau Wang
3:25 PM Roundtable Discussion With Audience Q&A
3:30 PM TCT 73: Impact of Routine MicroNet-Covered Embolic Prevention Stent System Use on Contemporary Carotid Revascularization – All-Comer PARADIGM Study Piotr Musialek
3:40 PM Roundtable Discussion With Audience Q&A
3:45 PM TCT 74: Proximal Balloon Occlusion Versus Distal Filter Protection in Carotid Artery Stenting – A Meta-analysis of Clinical Trial Data Jad Omran
3:55 PM Roundtable Discussion With Audience Q&A
Pharmacology: PCI and TAVR Accreditation: CME/CNE
Tuesday, October 13 2:00 PM - 4:00 PM Room: Moscone West, 3rd Floor, Room 3012
Pharmacology: PCI and TAVR 2:00 PM - 4:00 PM Moderators: Lisa K. Jennings, Neal S. Kleiman Discussants: Tayo A. Addo, Dimitrios Alexopoulos, Harold L. Dauerman, Hitinder S. Gurm, Carey D. Kimmelstiel, Michel R. Le May
2:00 PM TCT 75: Cangrelor Improves Ischemic Outcomes in Patients With Multivessel Disease and Single Vessel Disease Undergoing PCI – Insights From the CHAMPION PHOENIX Trial Freddy Abnousi
2:10 PM Roundtable Discussion With Audience Q&A
2:15 PM TCT 76: Six Versus 12 Months of Dual Antiplatelet Therapy After Percutaneous Coronary Intervention With Biodegradable-Polymer Sirolimus-Eluting Stents for Bifurcation Lesions – Insights From the I-LOVE-IT 2 Trial Bo Xu
2:25 PM Roundtable Discussion With Audience Q&A
2:30 PM TCT 77: Risk and Benefits of Triple Therapy in Patients Undergoing Percutaneous Coronary Stent Implantation Requiring Chronic Oral Anticoagulation – A Meta-analysis of 12 Trials Lucia Barbieri
2:40 PM Roundtable Discussion With Audience Q&A
2:45 PM TCT 78: Efficacy of Long-term Ticagrelor in Stented Patients in PEGASUS-TIMI 54 Marc Bonaca
2:55 PM Roundtable Discussion With Audience Q&A 3:00 PM TCT 79: Efficacy of Cangrelor in Lesions With High-Risk and Low-Risk Angiographic Characteristics – The CHAMPION PHOENIX Trial Gregg W. Stone
3:10 PM Roundtable Discussion With Audience Q&A
3:15 PM TCT 80: Favorable Effect of Optimal Lipid-Lowering Therapy on Neointimal Tissue Characteristics After Drug-Eluting Stent Implantation – Qualitative Optical Coherence Tomographic Analysis Ji-Yong Jang
3:25 PM Roundtable Discussion With Audience Q&A
3:30 PM TCT 81: Six Versus 12 Months of Dual Antiplatelet Therapy After Implantation of Biodegradable-Polymer Sirolimus-Eluting Stent – A Randomized Substudy of the I- LOVE-IT 2 Trial Yaling Han
3:40 PM Roundtable Discussion With Audience Q&A
3:45 PM TCT 82: Single Versus Dual Antiplatelet Therapy in Transcatheter Aortic Valve Replacement – A Meta-analysis of Safety and Efficacy Outcomes Rhanderson Cardoso
3:55 PM Roundtable Discussion With Audience Q&A
Renal Denervation for Hypertension Accreditation: CME/CNE
Tuesday, October 13 2:00 PM - 4:00 PM Room: Moscone West, 3rd Floor, Room 3020
Renal Denervation for Hypertension 2:00 PM - 4:00 PM Moderators: Michael A. Weber, Stephen G. Worthley Discussants: Darrel P. Francis, James R. Margolis, Atul Pathak, C. Venkata S. Ram, Robert S. Schwartz, Pedro de Araujo Goncalves
2:00 PM TCT 83: Long-term (24-Month) Blood Pressure Results of Catheter-Based Renal Artery Denervation – SYMPLICITY HTN-3 Randomized Controlled Trial Deepak L. Bhatt
2:10 PM Roundtable Discussion With Audience Q&A
2:15 PM TCT 84: Enhanced Circumferential Ablation Using a Multielectrode Bipolar/Unipolar Over-the-Wire Renal Denervation RF Catheter System With Closed-Loop Sensing Elazer R. Edelman
2:25 PM Roundtable Discussion With Audience Q&A 2:30 PM TCT 85: Safety and Performance of the EnligHTN Renal Denervation System in Patients With Severe Uncontrolled Hypertension – Twelve-Month Results From the EnligHTN II Study Melvin D. Lobo
2:40 PM Roundtable Discussion With Audience Q&A
2:45 PM TCT 86: Safety and Performance of the Next-Generation EnligHTN Renal Denervation System in Patients With Drug-Resistant Hypertension – 24-Month Results From a First-in-Human Multicentre Study Stephen G. Worthley
2:55 PM Roundtable Discussion With Audience Q&A
3:00 PM TCT 87: Noninvasive Renal Denervation Study Using Externally Delivered Focused Ultrasound in Severe Resistant Hypertension – One-Year Follow-up Results Roland E Schmieder
3:10 PM Roundtable Discussion With Audience Q&A
3:15 PM TCT 88: Transcatheter Perivascular Chemical Neurolysis to Produce Renal Denervation – Targeted, Local Delivery of Alcohol as a Viable Alternative to Radiofrequency Approaches Tim A. Fischell
3:25 PM Roundtable Discussion With Audience Q&A
3:30 PM TCT 89: Renal Sympathetic Denervation in Treatment-Resistant Essential Hypertension a Sham-Controlled, Double-blinded Randomized Trial (RESET trial) Ole Mathiassen
3:40 PM Roundtable Discussion With Audience Q&A
3:45 PM TCT 90: Sustained Beneficial Effects of Multielectrode Renal Denervation on Cardiac Adaptations in Resistant Hypertension – A 24-Month Follow-up Study Konstantinos Tsioufis
3:55 PM Roundtable Discussion With Audience Q&A
TAVR, Part 1 Accreditation: CME/CNE
Tuesday, October 13 2:00 PM - 4:00 PM Room: Moscone West, 3rd Floor, Room 3022
TAVR, Part 1 2:00 PM - 4:00 PM Moderators: Jeffrey J. Popma, Mathew Williams Discussants: Andreas Baumbach, Charles J. Davidson, Douglas G. Fraser, Karel T. Koch, Ganesh Manoharan, Amit Segev 2:00 PM TCT 91: Comparison of Portico and CoreValve Self-Expanding Transcatheter Heart Valves for the Treatment of Failed Surgical Aortic Bioprosthesis – Insights From the Valve-in-Valve International Data (VIVID) Registry Sami Alnasser
2:10 PM Roundtable Discussion With Audience Q&A
2:15 PM TCT 92: Transcatheter Aortic Valve Replacement in Asian Pacific Countries Sung-Han Yoon
2:25 PM Roundtable Discussion With Audience Q&A
2:30 PM TCT 93: Improvement in Renal Function and Its Impact on All-Cause Mortality After Transcatheter Aortic Valve Replacement (TAVR) – Experience From the PARTNER Trial Nirat Beohar
2:40 PM Roundtable Discussion With Audience Q&A
2:45 PM TCT 94: Balloon Postdilation of the Self-Expanding CoreValve Transcatheter Aortic Valve Bioprosthesis – Procedural Results and In-Hospital Outcomes From 3,532 Patients in the CoreValve US Pivotal and Continued Access Trials J. Kevin Harrison
2:55 PM Roundtable Discussion With Audience Q&A
3:00 PM TCT 95: The Long-term Hemodynamic Performance of Transcatheter Aortic Valve Replacement – A Report From the PARTNER I Trial Melissa Daubert
3:10 PM Roundtable Discussion With Audience Q&A
3:15 PM TCT 96: Self-Expanding TAVR in Patients with Failed Surgical Bioprosthesis: Results from the CoreValve US Expanded Use Study G. Michael Deeb
3:25 PM Roundtable Discussion With Audience Q&A
3:30 PM TCT 97: Transcatheter Aortic Valve Replacement Using the Self-Expanding Bioprosthesis – First Report From the Transcatheter Valve Therapies Registry Jeffrey J. Popma
3:40 PM Roundtable Discussion With Audience Q&A
3:45 PM TCT 98: Clinical Outcomes at 1-Year With a Repositionable Self-Expanding Transcatheter Aortic Valve Ganesh Manoharan
3:55 PM Roundtable Discussion With Audience Q&A
TAVR, Part 2 Accreditation: CME/CNE
Tuesday, October 13 2:00 PM - 4:00 PM Room: Moscone West, 3rd Floor, Room 3024
TAVR, Part 2 2:00 PM - 4:00 PM Moderators: Michael J. Reardon, Torsten P. Vahl Discussants: Robert J. Applegate, Robert M. Bersin, Christophe Dubois, Christoph A. Kaiser, Marco A. Perin, Giuseppe Tarantini
2:00 PM TCT 99: Valve Thrombosis After Trancatheter Aortic Valve Replacement – Incidence, Characteristics, and Outcomes John Jose Erungaren
2:10 PM Roundtable Discussion With Audience Q&A
2:15 PM TCT 100: Transcatheter Aortic Valve Replacement in Patients With End-Stage Renal Disease – One-Year Outcomes From the CoreValve US Expanded Use Study Daniel O'Hair
2:25 PM Roundtable Discussion With Audience Q&A
2:30 PM TCT 101: Experience With Cerebral Protection During Transcatheter Aortic Valve Replacement – The ALSTER Registry Tobias Schmidt
2:40 PM Roundtable Discussion With Audience Q&A
2:45 PM TCT 102: SAPIEN 3 Implantation in Failed Surgical Aortic Bioprostheses – Matched Comparison and Insights From the Valve-in-Valve International Data (VIVID) Registry Moritz Seiffert
2:55 PM Roundtable Discussion With Audience Q&A
3:00 PM TCT 103: National Variation in Post-TAVR Antithrombotic Therapy Utilization and Associated Outcomes – Insights From the STS/ACC TVT Registry Matthew Sherwood
3:10 PM Roundtable Discussion With Audience Q&A
3:15 PM TCT 104: Clinical Outcomes of Transcatheter Aortic Valve Replacement for Bicuspid Aortic Valve Stenosis Sung-Han Yoon
3:25 PM Roundtable Discussion With Audience Q&A
3:30 PM TCT 105: Transcatheter Aortic Valve Implantation Using a New Second-Generation TAVI System – J-Valve for High-Risk Patients With Pure Aortic Regurgitation Yingqiang Guo
3:40 PM Roundtable Discussion With Audience Q&A
3:45 PM TCT 106: Cardiovascular Magnetic Resonance for the Evaluation of Aortic Regurgitation Following Transcatheter Aortic Valve Replacement – Insights on Clinical Outcomes Henrique Ribeiro
3:55 PM Roundtable Discussion With Audience Q&A
Maintenance of Certification (MOC) Course I Accreditation: none
Tuesday, October 13 8:00 AM - 9:30 AM Room: Moscone South, Lower Level, Room 103
Interventional Cardiology 2015 Module Review 8:00 AM - 9:30 AM Moderator: Tayo A. Addo
8:00 AM Welcome and Introduction George D. Dangas
8:05 AM 2015 Module Review Discussants: Nicola Corvaja, Dmitriy N. Feldman, Robert T. Pyo
Maintenance of Certification (MOC) Course II Accreditation: none
Tuesday, October 13 9:30 AM - 11:00 AM Room: Moscone South, Lower Level, Room 103
Interventional Cardiology 2014 Update Module Review 9:30 AM - 11:00 AM Moderators: Tayo A. Addo, Emmanouil S. Brilakis
9:30 AM Welcome and Introduction George D. Dangas
9:35 AM 2014 Module Review Discussants: Nicola Corvaja, Dmitriy N. Feldman, Robert T. Pyo Maintenance of Certification (MOC) Course III Accreditation: none
Tuesday, October 13 11:00 AM - 12:30 PM Room: Moscone South, Lower Level, Room 103
Interventional Cardiology 2013 Update Module Review 11:00 AM - 12:30 PM Moderators: Tayo A. Addo, Emmanouil S. Brilakis
11:00 AM Welcome and Introduction Roxana Mehran
11:05 AM 2013 Module Review Discussants: Nicola Corvaja, Robert T. Pyo, Elias Sanidas
FDA Town Hall, Part 1, Tuesday, Oct. 13 Accreditation: CME/CNE
Tuesday, October 13 2:00 PM - 6:00 PM Room: Moscone West, 2nd Floor, Room 2007 - 2011
Session I. FDA's CDRH: Perspectives, Updates, and a Vision for the Future 2:00 PM - 2:45 PM Moderators: Gregg W. Stone, Bram D. Zuckerman Discussants: David E. Kandzari, Daniel T. Lemaitre, Martin B. Leon, Frank Litvack, Michael Minogue, Michael A. Mussallem, Jeffrey Shuren
2:00 PM My 3 Decades at FDA-CDRH: Historical Perspectives, Landmark Changes, and Major Accomplishments Bram D. Zuckerman
2:12 PM Keynote Lecture 1: A Revitalization Plan for the FDA-CDRH – Emphasis on Policy Changes, Innovation, and Technology Jeffrey Shuren
2:25 PM Roundtable Discussion With Audience Q&A
Session II. Early Feasibility Studies in the US: Status Review and Metrics for a Successful Program 2:45 PM - 3:35 PM Moderators: Andrew Farb, Michael J. Mack Discussants: Keith D. Dawkins, Juan F. Granada, David R. Holmes Jr., Dan Mans, James Rollins, Stanton J. Rowe, Sean Salmon, Changfu Wu 2:45 PM The Early Feasibility Study (EFS) Program: “First-Term” Report Card Andrew Farb
2:57 PM A “White Paper” From EFS Physician Enthusiasts: Honest Appraisals and Lessons Learned Michael J. Mack
3:07 PM Roundtable Discussion With Audience Q&A
Session III. Clinical Trials in the US 3:35 PM - 4:50 PM Moderator: Roxana Mehran Discussants: Angeles Alonso Garcia, Donald Cutlip, Keith D. Dawkins, Robert A. Harrington, John C Laschinger, Laura Mauri, Gregg W. Stone, George W. Vetrovec
3:35 PM Is the Answer Pragmatic/Simple Trials? Are They Really So “Simple”? Robert A. Harrington
3:47 PM “Big Data”: Opportunities and Challenges 1 – FDA Perspectives John C Laschinger
3:54 PM “Big Data”: Opportunities and Challenges 2 – EMA Perspectives Angeles Alonso Garcia
4:01 PM “Big Data”: Opportunities and Challenges 3 – Industry Perspectives Keith D. Dawkins
4:08 PM “Big Data”: Opportunities and Challenges 4 – Academia Perspectives Laura Mauri
4:15 PM Roundtable Discussion With Audience Q&A
Session IV. Medical Device Regulation, Patient Advocacy, and Reimbursement: Global Concerns and Solutions 4:50 PM - 6:00 PM Moderator: Aaron V. Kaplan Discussants: Angeles Alonso Garcia, Kevin Ballinger, Ori Ben-Yehuda, Hugo Campos, David J. Cohen, Louis B. Jacques, Brian S. Kersten, Jeffrey Shuren
4:50 PM Anticipated Changes in the European Regulatory Landscape: Impact on Device Development and Innovation Angeles Alonso Garcia
5:02 PM The Evolving CMS Reimbursement Process: How Can CMS Promote Innovation, and What Clinical Data Make a Difference? James Rollins
5:14 PM The Conundrum of Cost-effective but Unaffordable Care: The Plight of High-Tech New Interventional Therapies David J. Cohen
5:24 PM Together We’re better. On Engagement, Empowerment, and Autonomy Hugo Campos
5:34 PM Roundtable Discussion With Audience Q&A
Use of Bioresorbable Vascular Scaffolds in Complex Coronary Lesions Presented by the Taiwan Society of Cardiovascular Interventions (TSCI), Cardiovascular Intervention Association of Thailand (CIAT), Indonesian Heart Association, Japanese Association of Cardiovascular Intervention and Therapeutics (CVIT), and the Dutch Working Group of Interventional Cardiology (WIC) Accreditation: none
Tuesday, October 13 8:30 AM - 10:30 AM Room: Moscone North, Lower Level, Presentation Theater 2
Session I. Cases From Taiwan 8:30 AM - 8:53 AM Moderators: Jun-Jack Cheng, Yutaka Hikichi, Juey-Jen Hwang, Teguh Santoso, Wasan Udayachalerm
8:30 AM BRS in a Patient With Acute Coronary Syndrome Case Presenter: Shih-Hsien Sung
8:42 AM BRS in a CTO Lesion Case Presenter: Chiung-Jen Wu
Session II. Cases From Thailand 8:53 AM - 9:18 AM Moderators: Jun-Jack Cheng, Yutaka Hikichi, Juey-Jen Hwang, Teguh Santoso, Wasan Udayachalerm
8:53 AM BRS in a Double Bifurcation Left Main and LAD-Dg With 2-Year Follow-up OCT Case Presenter: Wasan Udayachalerm
9:06 AM BRS in a CTO With Complications Case Presenter: Damras Tresukosol
Session III. Cases From Indonesia 9:18 AM - 9:42 AM Moderators: Jun-Jack Cheng, Yutaka Hikichi, Juey-Jen Hwang, Teguh Santoso, Wasan Udayachalerm
9:18 AM BRS in a Left Main Trifurcation With Aneurysm Case Presenter: Teguh Santoso
9:30 AM BRS for In-Stent Stenosis With Fracture Case Presenter: Linda Lison
Session IV. Cases From Japan 9:42 AM - 10:06 AM Moderators: Jun-Jack Cheng, Yutaka Hikichi, Juey-Jen Hwang, Teguh Santoso, Wasan Udayachalerm
9:42 AM BRS in a Bifurcation Lesion Case Presenter: Sunao Nakamura
9:54 AM BRS in a CTO (With a Tip to Enhance the BRS Delivery) Case Presenter: Naoki Masuda
Session V. Cases From the Netherlands 10:06 AM - 10:30 AM Moderators: Jun-Jack Cheng, Yutaka Hikichi, Juey-Jen Hwang, Teguh Santoso, Wasan Udayachalerm
10:06 AM Kawasaki Disease Treated With BRS Case Presenter: Robert-Jan van Geuns
10:18 AM BRS to LIMA Graft With Total Reconstruction of the LAD Case Presenter: Jose P.S. Henriques
South American Perspectives on TAVI Presented by the Colegio Argentino de Cardioangiólogos Intervencionistas, Colegio Colombiano De Hemodinamia E Intervencionismo Cardiovascular, Sociedad Uruguaya de Cardiología, Sociedad Venezolana de Cardiología Intervencionista (SOVECI), Sociedade Brasileira de Hemodinâmica e Cardiologia Intervencionista (SBHCI) Accreditation: none
Tuesday, October 13 9:00 AM - 10:30 AM Room: Moscone North, Lower Level, Presentation Theater 1
Session I. Argentina Presents to Columbia 9:00 AM - 9:18 AM Moderators: Jose A. Condado, Celin Malkun
9:00 AM Results of the Argentine TAVI Registry With Follow-up Alejandro Cherro
9:10 AM Comments and Discussion Leader Commentator: Jorge Villegas
Session II. Colombia Presents to Venezuela 9:18 AM - 9:36 AM Moderators: Jose A. Condado, Celin Malkun
9:18 AM Ten Approaches for TAVI Access Antonio Enrique Dager
9:28 AM Comments and Discussion Leader Commentator: Carlos D Calderas
Session III. Argentina presents to Colombia 9:36 AM - 9:54 AM Moderators: Jose A. Condado, Celin Malkun
9:36 AM Coronary Disease and TAVI: When and How to Do PCI Oscar A. Mendiz
9:46 AM Comments and Discussion Leader Commentator: Marcelo E Halac
Session IV. Argentina Presents to Uruguay 9:54 AM - 10:12 AM Moderators: Jose A. Condado, Celin Malkun
9:54 AM TAVI in Low- and Intermediate-Risk Patients Ernesto M. Torresani
10:04 AM Comments and Discussion Leader Commentator: Ricardo Lluberas
Session V. Venezuela Presents to Brazil 10:12 AM - 10:30 AM Moderators: Jose A. Condado, Celin Malkun
10:12 AM CoreValve Latin American Experience Carlos D Calderas
10:22 AM Comments and Discussion Leader Commentator: Fausto Feres East Meets West: Complications of TAVI Presented by Coronary Atheroma and Interventional Cardiology Group (GACI); Bangladesh Society of Cardiovascular Intervention; British Cardiovascular Intervention Society; Italian Society of Invasive Cardiology (GISE); Working Group on Interventional Cardiology, The Israel Heart Society; and the Hong Kong College of Cardiology Accreditation: none
Tuesday, October 13 3:00 PM - 5:00 PM Room: Moscone North, Lower Level, Presentation Theater 1
East Meets West: Complications of TAVI 3:00 PM - 5:00 PM Moderator: Alain G. Cribier Discussants: Sergio Berti, Kam-Tim Chan, Ariel Finkelstein, Afzalur Rahman, Simon Redwood, Gennaro Sardella, Eric Van Belle, Chris Kwok Yiu Wong
3:00 PM Presentation From Israel: Annular Rupture During TAVI Ariel Finkelstein
3:10 PM Roundtable Discussion With Audience Q&A
3:20 PM Presentation From France: Paravalvular Leakage During TAVI Eric Van Belle
3:30 PM Roundtable Discussion With Audience Q&A
3:40 PM Presentation From Hong Kong: Vascular Complications During TAVI Kam-Tim Chan
3:50 PM Roundtable Discussion With Audience Q&A
4:00 PM Presentation From the United Kingdom: Stroke During TAVI Simon Redwood
4:10 PM Roundtable Discussion With Audience Q&A
4:20 PM Presentation From Italy: Coronary Occlusion During TAVI Gennaro Sardella
4:30 PM Roundtable Discussion With Audience Q&A
4:40 PM Presentation From Bangladesh: Cardiac Tamponade/Rhythm Disturbance During TAVI Afzalur Rahman
4:50 PM Roundtable Discussion With Audience Q&A
Featured Clinical Research II: Presentations to the Editors of Circulation Accreditation: CME
Tuesday, October 13 12:15 PM - 1:45 PM Room: Moscone South, Lower Level, Room 104
Presentations to the Editors of Circulation 12:15 PM - 1:45 PM Moderators: David P. Faxon, David O. Williams Discussants: J. Dawn Abbott, Theodore A. Bass, Donald Cutlip, Harold L. Dauerman, Chet Rihal
12:15 PM SORT-OUT VI: A Prospective Randomized Trial of a Durable-Polymer Zotarolimus- Eluting Stent Versus a Bioabsorbable-Polymer Biolimus-Eluting Stent in Patients With Coronary Artery Disease – Three-Year Outcomes Bent Raungaard
12:25 PM Roundtable Discussion With Audience Q&A
12:30 PM INNOVATION: A Prospective Randomized Trial of Primary Versus Deferred Stent Implantation in Patients With ST-Segment Elevation Myocardial Infarction Cheol Woong Yu
12:40 PM Roundtable Discussion With Audience Q&A
12:45 PM EPICURE: A Prospective, Double-blind, Placebo-Controlled, Randomized Trial of Darbepoetin in Patients With Anemia Prior to Transcatheter Aortic Valve Replacement Marina Urena
12:55 PM Roundtable Discussion With Audience Q&A
1:00 PM VISION: Evaluation of Optical Coherence Tomography–Guided Atherectomy in Patients Undergoing Peripheral Vascular Intervention Arne G. Schwindt
1:10 PM Roundtable Discussion With Audience Q&A
1:15 PM ALSTER-CERA: Evaluation of NOGA-Guided Intramyocardial Injection of a Long-Acting Erythropoietin Analogue in Patients With Ischemic Cardiomyopathy Martin W Bergmann
1:25 PM Roundtable Discussion With Audience Q&A
1:30 PM IBIS-4: Evaluation by Optical Coherence Tomography of High-Dose Statin Therapy in Untreated Lesions in Patients With ST-Segment Elevation Myocardial Infarction Lorenz Raber
1:40 PM Roundtable Discussion With Audience Q&A
Moderated Poster Abstract Session: Coronary and Peripheral Vascular Accreditation: none Tuesday, October 13 4:00 PM - 5:48 PM Room: Moscone West, 1st Floor
Coronary and Peripheral Vascular 4:00 PM - 5:48 PM Moderators: Louis A. Cannon, Manel Sabate Discussants: Pilar Dolcimascolo, John McB. Hodgson, Shams Munwar, Flavio L. Ribichini, Kimberly A. Skelding
4:00 PM A Novel Thin Strut (100 µm) Sirolimus-Eluting Bioresorbable Scaffold With Hybrid Cell Design: Preclinical Evaluation in Porcine Coronary Arteries Pawel Gasior
4:12 PM Development of a New Prediction Rule for Chronic Total Occlusion Recanalization Failure: The Prospective Global Registry for the Study of Chronic Total Occlusion Intervention (PROGRESS CTO) Score Georgios Christopoulos
4:24 PM Safety and Efficacy of a Device to Narrow the Coronary Sinus for the Treatment of Refractory Angina: A Single Center Real-World™ Experience Pieter R. Stella
4:36 PM Physiologic Assessment of Intermediate Coronary Artery Stenosis by Intravascular Ultrasound Radiofrequency Signal Analysis of Blood Speckles: A Comparison With Fractional Flow Reserve and Instantaneous Wave-Free Ratio Kozo Okada
4:48 PM Causes of Death After Percutaneous Coronary Intervention Versus Coronary Artery Bypass Grafting in Complex Coronary Artery Disease: 5-Year Follow-up of the SYNTAX Trial Milan Milojevic
5:00 PM Trends in Patient Characteristics and Outcomes of Percutaneous Coronary Intervention in the Elderly: Analysis of Medicare Beneficiaries From 2000 to 2012 Christian McNeely
5:12 PM Angiographic and Long-term Clinical Outcomes After Bare-Metal, First-Generation, and Second-Generation Drug-Eluting Stent Implantation for Left Main Coronary Artery Disease: From the Japanese Left Main Coronary Stenting Registry Masanobu Ohya
5:24 PM Drug-Eluting Balloons Versus Balloon Angioplasty in Femoropopliteal and Infrapopliteal Vascular Disease Interventions – A Meta-analysis of Randomized Controlled Studies Arun Kanmanthareddy
5:36 PM Increased Troponin Concentrations in Patients With Stable Coronary Artery Disease Are Associated With Thin-Cap Fibroatheroma and Future Major Adverse Cardiovascular Events Adam Brown Moderated Poster Abstract Session: Structural Accreditation: none
Tuesday, October 13 4:00 PM - 6:12 PM Room: Moscone West, 1st Floor
Structural 4:00 PM - 6:12 PM Moderators: Neil E. Moat, Anna Sonia Petronio Discussants: YunDai Chen, Douglas G. Fraser, Augusto D. Pichard, Harry Rakowski, Wojtek Wojakowski
4:00 PM 3-D Heart Models for Planning of Percutaneous Tricuspid Interventions Maurizio Taramasso
4:12 PM Cross-sectional Psoas Muscle Area Detected by Computed Tomography as a Measure of Frailty and Mortality in Patients Undergoing Transcatheter Aortic Valve Replacement Mike Saji
4:24 PM EURYDICE Registry: European Direct Aortic CoreValve Experience Giuseppe Bruschi
4:36 PM Durability of the Quality-of-Life Benefit of Transcatheter or Surgical Aortic Valve Replacement in High-Risk Patients With Aortic Stenosis: Two-Year Results From the CoreValve US Pivotal High Risk Trial Suzanne J. Baron
4:48 PM Patient and Healthcare System Benefits of Contemporary Transcatheter Aortic Valve Implantation (TAVI) Practice Neil Ruparelia
5:00 PM Transfemoral Aortic Valve Replacement With the Repositionable Lotus Valve Compared With the Balloon-Expandable Edwards Sapien 3 Valve Julia Seeger
5:12 PM Outcomes After Transcatheter Aortic Valve Implantation Using a Novel Balloon- Expandable Transcatheter Heart Valve: A Single Center Experience Costanza Pellegrini
5:24 PM The Impact of Transcatheter Aortic Valve Replacement on Therapy Utilization and Case Volumes in Germany, 2009-2013 Jan Pietzsch
5:36 PM Fully Percutaneous Transthoracic Left Atrial Entry and Closure to Deliver Large Caliber Transcatheter Mitral Valve Implants Toby Rogers
5:48 PM Transcatheter Mitral Valve Implantation: Six-Month Outcomes of First-in-Man Experience With an Apically Tethered Device Neil E. Moat 5:50 PM Roundtable Discussion With Audience Q&A
6:00 PM Prosthesis-Patient Mismatch After Aortic Valve-in-Valve Implantation: Insights From the Valve-in-Valve International Data (VIVID) Registry Sabine Bleiziffer
Can PCSK9 Inhibition Control LDL-C to Levels that Halt the Progression of Atherosclerosis? (Sponsored by The Medicines Company) Accreditation: none
Tuesday, October 13 6:30 AM - 8:00 AM Room: Moscone North, Lower Level, Room 132
Check-in and Breakfast 6:30 AM - 7:00 AM
Can PCSK9 Inhibition Control LDL-C to Levels That Halt the Progression of Atherosclerosis? 7:00 AM - 8:00 AM Chair: C. Michael Gibson Facultys: Evan A. Stein, Harvey D. White
7:00 AM Welcome & Opening Remarks Moderator: C. Michael Gibson
7:10 AM Residual Risk of Atherosclerosis With Optimal Standard of Care LDL-C Lowering Therapy: Oral Agents Harvey D. White
7:22 AM PCSK9 Monoclonal Antibodies: What Impact Can They Have in Halting Progression of Atherosclerosis? Evan A. Stein
7:36 AM Novel PCSK9 Therapies: What Will the Future Hold? C. Michael Gibson
7:50 AM Moderated Panel Discussion Moderator: C. Michael Gibson Evan A. Stein, Harvey D. White
Complex SFA Interventions: Evidence-Based Decision Making for New Technologies (Sponsored by Abbott) Accreditation: none
Tuesday, October 13 6:30 AM - 8:00 AM Room: Moscone North, Lower Level, Room 122
Check-in and Breakfast 6:30 AM - 7:00 AM
Complex SFA Interventions: Evidence-Based Decision Making for New Technologies 7:00 AM - 8:00 AM Facultys: Ethan Korngold, MD, John R. Laird Jr, Andrej Schmidt
7:00 AM Complex SFA Interventions: Evidence-Based Decision Making for New Technologies Discussants: Ethan Korngold, MD, John R. Laird Jr, Andrej Schmidt
Exploring Emerging Trends: Managing Large-Bore Complications and Venous Access Site (Sponsored by Cardinal Health) Accreditation: none
Tuesday, October 13 6:30 AM - 8:00 AM Room: Moscone North, Lower Level, Room 121
Check-in and Breakfast 6:30 AM - 7:00 AM
Exploring Emerging Trends: Managing Large-Bore Complications and Venous Access Site 7:00 AM - 8:00 AM Chair: Ron Waksman Facultys: Itshac Itsik Ben-dor, Nelson Bernardo, MD, Augusto D. Pichard
7:00 AM Introduction
7:05 AM New Trends in Access Site Closure: Venous Closure – An Unessential or Unrecognized Need? Augusto D. Pichard
7:20 AM 4,000 Patient Extravascular vs Anchor-Based Closure Data From a High-Volume Center Itshac Itsik Ben-dor
7:35 AM Emerging Strategies in Preventing and Managing Illiofemoral Complications: Existing Occlusion Techniques and New Occlusion Devices Nelson Bernardo, MD
7:50 AM Closing Remarks The Future of Coronary Physiology: Volcano and Philips' Joint Vision (Sponsored by Volcano Philips) Accreditation: none
Tuesday, October 13 6:30 AM - 8:00 AM Room: Moscone North, Lower Level, Room 123
Check-in and Breakfast 6:30 AM - 7:00 AM
The Future of Coronary Physiology: Volcano and Philips' Joint Vision 7:00 AM - 8:00 AM Chairs: Javier Escaned, Matthias Götberg, MD, Morton J. Kern, Patrick W. Serruys Facultys: Justin E. Davies, Allen Jeremias, Bert van Meurs
7:00 AM Welcome Chairs: Javier Escaned, Matthias Götberg, Morton J. Kern, Patrick W. Serruys
7:01 AM Rationale for Using iFR for Hemodynamic Evaluation of Coronary Stenoses Allen Jeremias
7:15 AM Using Physiology to Guide Your Treatment: Pullback, Prediction, and Post-PCI Assessment Justin E. Davies
7:30 AM Philips and Volcano: Charting the Future of Image-Guided Therapy Bert van Meurs
7:45 AM Question and Answer Moderator: Morton J. Kern Discussants: Javier Escaned, Matthias Götberg, MD, Patrick W. Serruys
Intra-aortic Balloon Counterpulsation for Percutaneous Aortic Valve or Complex PCI Procedures: Award-Winning Case Presentations (Sponsored by MAQUET Cardiovascular) Accreditation: none
Tuesday, October 13 6:30 AM - 8:00 AM Room: Moscone North, Lower Level, Room 124
Check-In and Breakfast 6:30 AM - 7:00 AM Intra-aortic Balloon Counterpulsation for Percutaneous Aortic Valve or Complex PCI Procedures 7:00 AM - 8:00 AM Chairs: Tayo A. Addo, George D. Dangas, Vijay Kunadian Facultys: Aung Myat, Masaki Tanabe, Lokien X van Nunen
7:00 AM Tough Management of Cardiogenic Shock Due to Acute Coronary Syndrome With Comorbidity of Septic Shock Case Presenter: Masaki Tanabe
7:15 AM Q&A
7:20 AM An Unusual Case of Post-operative ST-segment Elevation Following Coronary Artery Bypass Graft Surgery Case Presenter: Aung Myat
7:35 AM Q&A
7:40 AM Exhausted Coronary Autoregulation in Acute Myocardial Infarction: A Prerequisite for Effective Intra-aortic Balloon Pump Therapy Case Presenter: Lokien X van Nunen
7:55 AM Q&A
IVUS Reinvented in HD: The State of the Art in HD-IVUS (Sponsored by ACIST Medical Systems and Medtronic, PLC) Accreditation: none
Tuesday, October 13 6:30 AM - 8:00 AM Room: Moscone North, Lower Level, Room 125
Check-in and Breakfast 6:30 AM - 7:00 AM
IVUS Reinvented in HD: The State of the Art in HD-IVUS 7:00 AM - 8:00 AM Chair: Gary S. Mintz Facultys: Jeffrey Chambers, Jasvindar Singh, MD
7:00 AM IVUS Reinvented in HD: The State of the Art in HD-IVUS Gary S. Mintz
7:20 AM The Role of HD-IVUS in Complex PCI and Left Main Interventions Jasvindar Singh, MD
7:35 AM Treating Heavily Calcified Lesions: Why Imaging? Jeffrey Chambers
7:50 AM Q&A Moderator: Gary S. Mintz
PiCSO: Novel Strategies in PCI – Targeting Impaired Myocardial Perfusion (Sponsored by Miracor Medical System) Accreditation: none
Tuesday, October 13 6:30 AM - 8:00 AM Room: Moscone North, Lower Level, Room 120
Check-in and Breakfast 6:30 AM - 7:00 AM
PiCSO: Novel Strategies in PCI – Targeting Impaired Myocardial Perfusion 7:00 AM - 8:00 AM Chairs: Werner Mohl, MD, PhD, Gregg W. Stone, Azfar G. Zaman, MD Faculty: Adrian P. Banning
7:00 AM Welcome Chair: Werner Mohl, MD, PhD
7:05 AM Myocardial Perfusion, Salvage, and Infarct Size After STEMI: What Are the Remaining Challenges? Gregg W. Stone
7:20 AM Can We Measure Microvascular Function and Tailor Additional Therapies When Treating STEMI? Adrian P. Banning
7:35 AM PiCSO to Improve Myocardial Perfusion During PCI: The European Experience Azfar G. Zaman, MD
7:50 AM Discussion and Summary Chair: Gregg W. Stone
Practical Current and Future Approaches to Leaving Nothing Behind (Sponsored by TriReme Medical) Accreditation: none
Tuesday, October 13 6:30 AM - 8:00 AM Room: Moscone North, Lower Level, Room 130
Check-in and Breakfast 6:30 AM - 7:00 AM
Practical Current and Future Approaches to Leaving Nothing Behind 7:00 AM - 8:00 AM Chair: Martin B. Leon Facultys: J. A. Mustapha, Jasvindar Singh, MD, Thomas Zeller
7:00 AM Introduction Martin B. Leon
7:10 AM Chocolate PTA: Currently the Most Viable Option for BTK J. A. Mustapha
7:20 AM Peripheral Chocolate DCB: ENDURE Study Interim Results Thomas Zeller
7:30 AM Chocolate PTCA: Optimal Vessel Prep for BVS Jasvindar Singh, MD
7:40 AM Coronary Chocolate: Clinical Pathway Jasvindar Singh
7:50 AM Q&A Moderator: Martin B. Leon
Edited Taped Cases III: Interesting and Unusual PCI Accreditation: none
Tuesday, October 13 9:00 AM - 10:20 AM Room: Presentation Theater 3, Moscone South, Lower Level, Exhibit Hall
Edited Taped Cases III: Interesting and Unusual PCI 9:00 AM - 10:20 AM Moderators: A.J. Conrad C. Smith, Rod H. Stables Discussants: Talib Majwal, Dinesh Shah
9:00 AM An Ostial Lesion of a Large Estatic Right Coronary Artery Treated by a Large Self- Apposing Stent via a New Balloon Delivery System A.J.J. IJsselmuiden
9:12 AM Roundtable Discussion With Audience Q&A
9:20 AM Successful PCI of Chronically Occluded Right Coronary Artery Using Novel Microcatheter (NovaCross™) Leszek Bryniarski 9:32 AM Roundtable Discussion With Audience Q&A
9:40 AM Disobliteration of Aggressive In-Stent Restenosis Using Eccentric Excimer Laser Catheter John Rawlins
9:52 AM Roundtable Discussion With Audience Q&A
10:00 AM Implanting AXXESS(TM) - the Use of a Dedicated Bifurcation Stent within Heavy Coronary Calcification Peter O'Kane
10:12 AM Roundtable Discussion With Audience Q&A
Edited Taped Cases IV: Fascinating Peripheral Vascular Intervention Accreditation: none
Tuesday, October 13 9:00 AM - 10:00 AM Room: Moscone South, Lower Level, Exhibit Hall, Presentation Theater 4
Edited Taped Cases IV: Fascinating Peripheral Vascular Intervention 9:00 AM - 10:00 AM Moderators: Issam D. Moussa, Michael H. Wholey Discussants: Michel Camille Henry, Aljoscha Rastan
9:00 AM Pressure Wire as a Guide to Aortoarteritis Intervention Aditya Sai Madhavpeddi
9:12 AM Roundtable Discussion With Audience Q&A
9:20 AM Tack Endovascular System for Dissection Repair Andrej Schmidt
9:32 AM Roundtable Discussion With Audience Q&A
9:40 AM OCT Guided Atherectomy of 30cm SFA Lesion Arne G. Schwindt
9:52 AM Roundtable Discussion With Audience Q&A
Edited Taped Cases V: Fascinating PCI Approaches Accreditation: none Tuesday, October 13 10:00 AM - 11:00 AM Room: Presentation Theater 4, Moscone South, Lower Level, Exhibit Hall
Edited Taped Cases V: Fascinating PCI Approaches 10:00 AM - 11:00 AM Moderators: Sameer Mehta, George W. Vetrovec Discussants: Payam Dehghani, Jeff Marshall
10:00 AM Using Angiosync OFDI Guidance to Aid Bioabsorbable Scaffold Placement Fraser Witherow
10:12 AM Roundtable Discussion With Audience Q&A
10:20 AM Cardiovascular Procedure Silvio J. Bezerra
10:32 AM Roundtable Discussion With Audience Q&A
10:40 AM Demonstration of a Novel Catheter for Thermodilution-Derived Measurement of Absolute Coronary Blood Flow and Microvascular Resistances Bernard De Bruyne
10:52 AM Roundtable Discussion With Audience Q&A
Absorb: Pivotal Data for a New Therapy (Sponsored by Abbott) Accreditation: none
Tuesday, October 13 11:30 AM - 12:30 PM Room: Moscone North, Lower Level, Hall D, Presentation Theater 1
Absorb: Pivotal Data Sets for a New Therapy 11:30 AM - 12:30 PM Facultys: Felipe Hernandez, MD, Ashok Seth, Gregg W. Stone, Corrado Tamburino
11:30 AM Investigator Sponsored Studies and International Registry Data Corrado Tamburino
11:45 AM REPARA Registry: Immediate and 30 Day Results Felipe Hernandez, MD
12:00 PM Real-World Clinical Outcomes Ashok Seth
12:15 PM ABSORB Clinical Trial Data Gregg W. Stone Challenging Lesions in a Real-World Patient Population (Sponsored by Medtronic Cardiac) Accreditation: none
Tuesday, October 13 11:30 AM - 12:30 PM Room: Moscone South, Lower Level, Exhibit Hall, Presentation Theater 3
Challenging Lesions in a Real-World Patient Population 11:30 AM - 12:30 PM Chair: Roxana Mehran Facultys: Lianglong Chen, MD, Matthias Gotberg, MD, Chaim S. Lotan, Kinzo Ueda, MD
11:30 AM Welcome Chair: Roxana Mehran
11:35 AM Case #1: Perspective From China - Large Proximal Lesion in Younger Patient With Diabetes Case Presenter: Lianlong Chen, MD
11:45 AM Case #2: Perspective From Japan - Elderly Patient With Heavily Califified Lesions Case Presenter: Kinzo Ueda, MD
11:51 AM Discussion Moderator: Roxana Mehran
12:01 PM Case #3: Perspective from Sweden - Longer Term DAPT in PCI Case Presenter: Matthias Gotberg, MD
12:09 PM Case #4: Perspective From Israel - Elderly Patient With Aortic Stenosis Case Presenter: Chaim S. Lotan
12:15 PM Discussion and Closing Comments Moderator: Roxana Mehran
Taking Control of Platelet Inhibition in PCI (Sponsored by The Medicines Company) Accreditation: none
Tuesday, October 13 11:30 AM - 12:30 PM Room: Moscone North, Lower Level, Hall D, Presentation Theater 2
Taking Control of Platelet Inhibition in PCI 11:30 AM - 12:30 PM Chair: C. Michael Gibson Facultys: Ehtisham Mahmud, Duane S. Pinto
11:30 AM Understanding Platelet and Thrombin Inhibition in the Acute Care Setting C. Michael Gibson
11:45 AM Resolving the Complexity in Clinical Practice Duane S. Pinto
12:00 PM Improving the CV Pathways of Care Ehtisham Mahmud
12:15 PM Interactive Discussion and Debate Moderator: C. Michael Gibson Discussants: Ehtisham Mahmud, Duane S. Pinto
Tryton Pivotal: Randomized Trial and Confirmatory Study – Implications for Everyday Practice (Sponsored by Tryton Medical, Inc.) Accreditation: none
Tuesday, October 13 11:30 AM - 12:30 PM Room: Moscone South, Lower Level, Exhibit Hall, Presentation Theater 4
Tryton Pivotal: Randomized Trial and Confirmatory Study – Implications for Everyday Practice 11:30 AM - 12:30 PM Chairs: Dean J. Kereiakes, Martin B. Leon Facultys: Antonio L. Bartorelli, Philippe Généreux, James B. Hermiller Jr, Jens Flensted Lassen, Maciej Lesiak
11:30 AM Introduction and Objectives Chair: Dean J. Kereiakes
11:35 AM Lesion Coverage: Insights From the Bench Top Maciej Lesiak
11:44 AM Lesion Coverage: Insights From Intravascular Imaging Antonio L. Bartorelli
11:53 AM Lesion Treatment: Insights From Clinical Literature James B. Hermiller Jr
12:02 PM Late Breaking Tryton Confirmatory Study Results Philippe Généreux
12:11 PM Implications for Everyday Practice Treating Bifurcations – Integrating Dedicated Technology Jens Flensted Lassen
12:20 PM Discussion and Key Messages Moderator: Martin B. Leon
Clinical Kaleidoscope of Novel Interventional Technologies (Sponsored by Meril Life Sciences) Accreditation: none
Tuesday, October 13 1:00 PM - 2:00 PM Room: Moscone North, Lower Level, Hall D, Presentation Theater 2
Clinical Kaleidoscope of Novel Interventional Technologies 1:00 PM - 2:00 PM Facultys: Alexandre Abizaid, Richard Biannco, MD, Deepak Davidson, MD, Ashok Seth
1:00 PM Biomimicry in DES Design: The Science Behind BioMime and meriT Clinical Update Alexandre Abizaid
1:12 PM Most Complex Cases During My Practice Deepak Davidson, MD
1:24 PM Journey From Substance to Sublime: MeRes100 Science and Clinical Update Ashok Seth
1:36 PM MyVal Science and Preclinical Update Richard Biannco, MD
1:48 PM Panel Discussion
Evolut R Recapturability: The New Standard in TAVR (Sponsored by Medtronic, Inc.) Accreditation: none
Tuesday, October 13 1:00 PM - 2:00 PM Room: Moscone South, Lower Level, Exhibit Hall, Presentation Theater 4
Evolut R Recapturability: The New Standard in TAVR 1:00 PM - 2:00 PM Chairs: Ian T. Meredith, Mathew Williams Facultys: Eberhard Grube, James B. Hermiller Jr, Jeffrey J. Popma, Wilson Y. Szeto 1:00 PM Welcome and Objectives Chair: Ian T. Meredith
1:10 PM Challenging Vascular Access Mathew Williams
1:25 PM Recapturability and Repositioning Wilson Y. Szeto
1:40 PM Evolut R in a Failed Surgical Bioprosthetic Valve Jeffrey J. Popma
1:55 PM Wrap Up & Discussion Chair: Mathew Williams
A Frontline Platform for Transcatheter Mitral and Tricuspid Repair (Sponsored by Mitralign) Accreditation: none
Tuesday, October 13 1:00 PM - 2:00 PM Room: Moscone South, Lower Level, Exhibit Hall, Presentation Theater 3
A Front Line Platform for Transcatheter Mitral and Tricuspid Repair 1:00 PM - 2:00 PM Facultys: Rebecca T. Hahn, Azeem Latib, Scott Lim, Neil E. Moat, Joachim Schofer
1:00 PM Introduction: Transcatheter Mitral and Tricuspid Repair: A Surgeon's Perspective Moderator: Scott Lim Neil E. Moat
1:05 PM Mitralign Mitral Repair: Device and Clinical Data Updates Moderator: Scott Lim Azeem Latib Discussant: Rebecca T. Hahn
1:20 PM Mitralign Tricuspid Repair with a Novel Transcatheter Annuloplasty Device Moderator: Neil E. Moat Joachim Schofer Discussant: Rebecca T. Hahn
1:35 PM Mitralign Tricuspid Repair: The Echocardiologist's Perspective Moderator: Scott Lim Rebecca T. Hahn Discussant: Joachim Schofer
1:55 PM Closing Remarks: The Front Line Platform for Mitral and Tricuspid Repair Moderator: Rebecca T. Hahn Scott Lim Discussants: Neil E. Moat, Joachim Schofer
Transcatheter Mitral Valve Technologies: Preparing for the Future (Sponsored by Abbott) Accreditation: none
Tuesday, October 13 1:00 PM - 2:00 PM Room: Moscone North, Lower Level, Hall D, Presentation Theater 1
Transcatheter Mitral Valve Technologies: Preparing for the Future 1:00 PM - 2:00 PM Facultys: Michael J. Mack, Jason H. Rogers, Paul Sorajja
1:00 PM A Landscape Overview of Future Transcatheter Mitral Valve Technologies Michael J. Mack
1:15 PM What We Know Today: Current Experience With MitraClip Jason H. Rogers
1:25 PM Establishing a Mitral Valve Center for the Future Paul Sorajja
1:40 PM Panel Discussion/Q&A
The “Evolving Era” of Transcatheter Valve Therapies: New Frontiers in the Treatment of Aortic, Mitral, and Tricuspid Valve Disease (Sponsored by the Cardiovascular Research Foundation) (Supported by Edwards Lifesciences) Accreditation: none
Tuesday, October 13 6:00 PM - 8:00 PM Room: Hilton Union Square, Ballroom Level, Continental Ballroom 5-6
Chairs: Martin B. Leon, Michael J. Mack Facultys: Anson Cheung, Rebecca T. Hahn, James B. Hermiller Jr, Susheel Kodali, Azeem Latib, Raj Makkar, Jason H. Rogers, Joachim Schofer, Lars Sondergaard, Vinod H. Thourani, Alec S. Vahanian
Check-in and Reception 6:00 PM - 6:30 PM
New Milestones in the Safety and Efficacy of TAVR 6:30 PM - 8:00 PM Moderator: Martin B. Leon Discussants: Susheel Kodali, Raj Makkar, Vinod H. Thourani, Alec S. Vahanian
6:30 PM Landscape and Controversies Martin B. Leon
6:35 PM Roundtable Discussion: Changing Clinical Standards and Indications, the Minimalist Strategy, Enhanced Technologies, Durability Considerations, and the “New” Heart Team
II. Assessment of New Mitral Valve Therapies 7:10 PM - 7:40 PM Moderator: Michael J. Mack Panelists: Anson Cheung, James B. Hermiller Jr, Lars Sondergaard
7:10 PM Landscape and Controversies Michael J. Mack
7:15 PM Roundtable Discussion: Novel Surgical Options, Functional MR Controversies, New Transcatheter Mitral Technologies, and Clinical Trial Strategies
III. The “Brave New World” of Tricuspid Valve Disease 7:40 PM - 8:00 PM Moderator: Rebecca T. Hahn Panelists: Azeem Latib, Jason H. Rogers, Joachim Schofer
7:40 PM Landscape and Controversies Rebecca T. Hahn
7:45 PM Roundtable Discussion: Clinical Indications, Patient Selection and Goals of Therapy, Novel Transcatheter Devices, and Imaging Considerations
Antiplatelet Agent Dilemmas: Tough Cases, New Options (Sponsored by the Cardiovascular Research Foundation) (Supported by The Medicines Company) Accreditation: none
Tuesday, October 13 6:00 PM - 8:00 PM Room: Hilton Union Square, Ballroom Level, Continental Ballroom 1-4
Check-in and Reception 6:00 PM - 6:30 PM
SECTION I. INTRODUCTION TO CANGRELOR 6:30 PM - 7:24 PM Moderator: Robert A. Harrington Discussants: Stefan K. James, Ajay J. Kirtane, Roxana Mehran, Freek W.A. Verheugt, Harvey D. White
6:30 PM Oral Preloading Before PCI: Evidence for Safety and Efficacy Deepak L. Bhatt
6:40 PM Cangrelor: Novel Uses of a Rapidly Acting IV P2Y12 Inhibitor in PCI Gregg W. Stone
6:50 PM Nuances of Integrating Cangrelor Into Practice (Dose, Duration, Transitions, Etc.) Deepak L. Bhatt
7:00 PM Implications Of P2Y12 Inhibition For Cardiac Surgery Cornelius (Mac) Dyke, MD
7:10 PM Discussion
SECTION II. TOUGH CASES (WITH AUDIENCE RESPONSE) 7:24 PM - 8:00 PM Moderator: E. Magnus Ohman Discussants: Stefan K. James, Ajay J. Kirtane, Roxana Mehran, Freek W.A. Verheugt, Harvey D. White
7:24 PM Case 1: Long-term DAPT – A Difficult Decision Case Presenter: Tullio Palmerini
7:36 PM Case 2: Recent Anterior STEMI, Recent DES, and Recent Intracranial Bleed Case Presenter: Morton J. Kern
7:48 PM Case 3: Recent DES on DAPT, LAA Closure for Atrial Fibrillation (Off VKA), and Recent Embolic Stroke Case Presenter: Matthew J. Price
Below-the-Knee Intervention: Emerging Technological Opportunities in the Drug-Delivery Era (Sponsored by the Cardiovascular Research Foundation) (Supported by Abbott, Boston Scientific Corporation, Cardiovascular Systems, Inc., Cook Medical, and Medtronic, Inc.) Accreditation: none
Tuesday, October 13 6:00 PM - 8:00 PM Room: Hilton Union Square, Ballroom Level, Imperial Ballroom AB
Check-in and Reception 6:00 PM - 6:30 PM Below-the-Knee Intervention: Emerging Technological Opportunities in the Drug Delivery Era 6:30 PM - 8:00 PM Chair: Juan F. Granada Moderator: J. A. Mustapha Discussants: George L Adams, Thomas Zeller
6:30 PM Anatomical and Clinical Challenges in BTK Intervention Today (Case-Based Presentation) Case Presenter: George L Adams
6:35 PM Technical Challenges and Therapeutic Options in Real-World BTK Interventions (Case- Based Presentation) J. A. Mustapha
6:45 PM Moderated Discussion
6:55 PM A Critical Review of the Clinical Data in BTK Intervention Thomas Zeller
7:05 PM Emerging Drug-Delivery Technologies for BTK Intervention Juan F. Granada
7:15 PM Direct Drug Delivery George L Adams
7:35 PM Challenges in Designing and Conducting a Successful BTK Trial - Telestrator Demonstration George L Adams
7:50 PM Moderated Discussion
The Interventional Toolbox for Complex Higher-Risk (and Indicated) Patients (CHIP) (Sponsored by the Cardiovascular Research Foundation) (Supported through educational grants from Abbott, ABIOMED, Inc., Boston Scientific Corporation, Cardiovascular Systems, Inc., and Medtronic, Inc.) Accreditation: none
Tuesday, October 13 6:00 PM - 8:00 PM Room: Hilton Union Square, Grand Ballroom Level, Grand Ballroom A
Chairs: J. Aaron Grantham, Ajay J. Kirtane Facultys: Emmanouil S. Brilakis, Philippe Généreux, Jeffrey W. Moses, Manish A. Parikh
Check-in and Reception 6:00 PM - 6:30 PM
Part I: High-Risk PCI 6:30 PM - 7:02 PM Moderator: Ajay J. Kirtane Discussants: Emmanouil S. Brilakis, J. Aaron Grantham, Philippe Généreux, Navin K. Kapur, Manish A. Parikh
6:30 PM PCI of High-Risk Patients Under Hemodynamic Support: For Whom and With What? Navin K. Kapur
6:41 PM High-Risk PCI Case Review Case Presenter: Ajay J. Kirtane
Part II: CTO PCI 7:02 PM - 7:34 PM Moderator: J. Aaron Grantham Discussants: Emmanouil S. Brilakis, Philippe Généreux, Navin K. Kapur, Ajay J. Kirtane, Manish A. Parikh
7:02 PM The Hybrid Approach to CTO PCI: What it is, and How It Has Changed CTO PCI J. Aaron Grantham
7:13 PM Hybrid CTO Case Review: Clinical Presentation/Angiogram, Discussion of Strategies, Discussion of What Was Done Case Presenter: Emmanouil S. Brilakis
7:21 PM Summary
Part III: Atherectomy and Calcium 7:34 PM - 8:00 PM Moderator: Emmanouil S. Brilakis Discussants: J. Aaron Grantham, Philippe Généreux, Ajay J. Kirtane, Jeffrey W. Moses, Manish A. Parikh
7:34 PM The Importance of Coronary Calcification in Complex PCI: Data and Devices Philippe Généreux
7:40 PM Calcified Anatomy Case Review: Clinical Presentation/Angiogram, Discussion of Strategies, Discussion of What Was Done Case Presenter: Manish A. Parikh
7:53 PM Summary
CRF Pavilion Program Accreditation: none
Tuesday, October 13 9:00 AM - 1:00 PM Room: Moscone South, Lower Level, CRF Pavilion CRF Pavilion Program 9:00 AM - 1:00 PM
9:00 AM Live Stream Live Case from Endovascular Theater: Live Cases: Lower Extremity With Walnut Hill Medical Center, Dallas, TX
10:30 AM Discussion with International Partners Discussants: Anibal A. Damonte, Oscar A. Mendiz
11:00 AM Skirball Center for Innovation and Diagnostic and Interventional Cardiology Ad Interview Key Opinion Leaders
12:00 PM CRF Clinical Trials Center Presents "CRF's Approach to Product Development" Ori Ben-Yehuda Discussants: Ioanna Kosmidou, Laura LaSalle, Melissa Nichols
12:30 PM CRF Clinical Trials Center Presents "Funding Research From a VC Perspective" Tamir Wolf Discussant: Ori Ben-Yehuda
Digital Zone - TECH Talks II Accreditation: none
Tuesday, October 13 11:00 AM - 3:30 PM Room: Moscone South, Lower Level, Digital Zone, Exhibit Hall
Featured TECH Talk 11:00 AM - 11:30 AM
11:00 AM The Future of Health and Medicine. Where can Technology take Us? Daniel Kraft
11:15 AM Q&A
Meta 11:30 AM - 12:00 PM
PhysIQ 12:00 PM - 12:30 PM
Break 12:30 PM - 2:00 PM
Rhythm Diagnostic Systems 2:00 PM - 2:30 PM VitalConnect 2:30 PM - 3:00 PM
PVLoops LLC 3:00 PM - 3:30 PM
Meet the Trialists II Accreditation: CME/CNE
Tuesday, October 13 2:00 PM - 3:15 PM Room: Moscone West, 3rd Floor, Room 3000
Meet the Trialists II 2:00 PM - 3:15 PM Moderator: Sunil V. Rao Discussants: Mark Andrew Hlatky, E. Magnus Ohman, Molly Szerlip
2:00 PM EXPLORE: A Prospective Randomized Trial of Chronic Total Occlusion Intervention Versus Medical Therapy After Successful Primary Angioplasty in Patients With ST- Segment Elevation Myocardial Infarction Jose P.S. Henriques
2:05 PM Roundtable Discussion With Audience Q&A
2:15 PM RIVER-PCI: A Prospective, Double-Blind, Placebo-Controlled Randomized Trial of Ranolazine in Patients With Incomplete Revascularization After Coronary Intervention Giora Weisz
2:20 PM Roundtable Discussion With Audience Q&A
2:30 PM TOTAL: A Prospective Randomized Trial of Thrombus Aspiration in Patients With ST- Segment Elevation Myocardial Infarction - One-Year Outcomes Sanjit S. Jolly
2:35 PM Roundtable Discussion With Audience Q&A
2:45 PM FRI- A Prospective Randomized Trial of Thrombus Aspiration in Patients With ST- Segment Elevation Myocardial Infarction Presenting Late After Symptom Onset Steffen Desch
2:50 PM Roundtable Discussion With Audience Q&A
3:00 PM PLATFORM: Quality of Life and Economic Outcomes of An FFR-CT Diagnostic Strategy in Patients With Suspected Coronary Artery Disease Mark Andrew Hlatky
3:05 PM Roundtable Discussion With Audience Q&A African Heart Summit Accreditation: none
Tuesday, October 13 3:00 PM - 6:00 PM Room: Moscone North, Lower Level, Presentation Theater 2
Session I. Introduction 3:00 PM - 3:05 PM Moderator: Hugh J. Linnehan
3:00 PM Introduction of Session Jack C. Lewin
Session II. Epidemiology of Heart Disease in Africa 3:05 PM - 3:57 PM Moderator: Hugh J. Linnehan Discussants: Graham A. Cassel, Mohamed Sobhy
3:05 PM Ischemic Heart Disease and Acute Coronary Syndrome Bernard J. Gersh
3:17 PM Nonischemic Heart Disease, Part 1: Rheumatic Heart Disease Mpiko Ntsekhe
3:29 PM Nonischemic Heart Disease, Part 2: HIV-Related CV Disease Mpiko Ntsekhe
3:41 PM Roundtable Discussion: Opportunities to Reduce CV Morbidity and Mortality in Africa
Session III. Current Management of STEMI in Africa 3:57 PM - 4:30 PM Moderator: Jack C. Lewin Discussants: Awad AA Mohamed, Harun A Otieno
3:57 PM PCI and Thrombolysis for STEMI in Africa Habib Gamra
4:09 PM Distribution of Cath Labs Throughout Africa Graham A. Cassel
4:19 PM Roundtable Discussion: Opportunities for Reducing ACS Mortality
Break 4:30 PM - 4:45 PM Session IV. Research Challenges and Education Opportunities in Africa 4:45 PM - 6:00 PM
4:45 PM Research Challenges Moderator: Hugh J. Linnehan
5:15 PM Educational Opportunities Moderator: Jack C. Lewin
Interactive Technology Center: Hands on Hearts Accreditation: none
Tuesday, October 13 8:00 AM - 2:00 PM Room: Moscone North, Lower Level, Hall D
Hands on Hearts 8:00 AM - 2:00 PM Discussants: Tobias Koppara, Robert Kutys, Elena Ladich, Michelle Olson, Maria E. Romero
ITC and Demonstration Theater - TAVR Accreditation: none
Tuesday, October 13 9:00 AM - 11:45 AM Room: Moscone North, Lower Level, Demonstration Theater, Hall D
Session I. TAVR 9:00 AM - 11:45 AM Moderators: Raj Makkar, Michael J. Reardon Discussants: Philipp Blanke, James M. McCabe, Torsten P. Vahl
9:00 AM Practical CT Reading and Vascular Analysis for Access Site Evaluation Philipp Blanke
9:10 AM Vascular Access and Closure Techniques: A Step Wise Approach Torsten P. Vahl
9:20 AM Technical Approaches and Options for Vascular Complication Management Hasan Jilaihawi
9:30 AM Roundtable Discussion with Audience Q&A 9:40 AM The Human Aortic Valve: Technical Landmarks and Considerations for TAVR Implantation James M. McCabe
9:50 AM Practical CT Reading and Analysis of Aortic Annulus and Associated Structures Philipp Blanke
10:00 AM Practical Echo Reading and Analysis of Aortic Annulus and Associated Structures Rebecca T. Hahn
10:10 AM Roundtable Discussion with Audience Q&A
10:20 AM Intra-Procedural Echo Guidance in TAVR Procedures Rebecca T. Hahn
10:30 AM Aortic Valve Patho-Biology: Anatomical Implications for TAVR Performance James M. McCabe
10:40 AM Roundtable Discussion with Audience Q&A
Hands-On-Technology Demonstration 10:50 AM - 11:45 AM Moderators: Samir R. Kapadia, Nicolo Piazza Discussants: Marco Barbanti, Axel Linke, Vinod H. Thourani, Torsten P. Vahl
10:50 AM Lotus (BSCI) Michael J. Reardon
11:00 AM Direct Flow Isaac George
11:10 AM Sapien 3 (Edwards) Torsten P. Vahl
11:20 AM CoreValve Evolut R (Medtronic) Torsten P. Vahl
11:30 AM Roundtable Discussion with Audience Q&A
Interventional Innovation, Part 2: TCT 2015 Innovation "Shark Tank" Competition Accreditation: none
Tuesday, October 13 8:00 AM - 12:00 PM Room: Moscone West, 2nd Floor, Room 2007 - 2011 TCT 2015 Innovation Competition 8:00 AM - 12:00 PM Judges: Louis A. Cannon, Peter J. Fitzgerald, Juan F. Granada, Frank Litvack, Chaim S. Lotan, Antoine Papiernik, Martin T. Rothman, Ron Waksman, Tamir Wolf
8:00 AM How Will the Digital Health Revolution Impact Patients, Clinical Practitioners, and Clinical Research in the Future Daniel Kraft
8:15 AM TCT 2015 Innovation Competition: Introduction and Scoring Methodology Juan F. Granada
8:20 AM Median Nerve Neuromodulation: A Novel Approach to Refractory Hypertension (Valencia Technologies) Dave Peterson
8:28 AM Q&A From the Sharks Moderator: Martin T. Rothman
8:40 AM Hilbert Paradox: A Unique Way of Worldwide Capture and Correlation of Digital Health Data (HPX) Bart Segers
8:48 AM Q&A From the Sharks Moderator: Peter J. Fitzgerald
9:00 AM Guidewire-Based Autonomic Neural Sensing From the Artery Lumen: Applications in Renal Denervation, Cancer, and Dysautonomias (Autonomix) Robert S. Schwartz
9:08 AM Q&A From the Sharks Moderator: Chaim S. Lotan
9:20 AM A Novel Left Atrial Pressure Monitoring System for Heart Failure (Vectorious) Leor Perl
9:28 AM Q&A From the Sharks Moderator: Louis A. Cannon
9:40 AM A Low-Risk, Percutaneous Solution for Late-Stage Heart Failure (Aortix) Manesh R. Patel
9:48 AM Q&A From the Sharks Moderator: Ron Waksman
10:00 AM LA Novel Transcatheter Mitral Valve Replacement Device (AccuFit) Patrick W. Serruys
10:08 AM Q&A From the Sharks Moderator: Antoine Papiernik
10:20 AM Therapeutic Intravascular Ultrasound for Pulmonary Hyptertension (SoniVie) Alex M. K. Rothman
10:28 AM Q&A From the Sharks Moderator: Juan F. Granada
10:40 AM Creating a New Paradigm for Pulmonary Embolism Intervention (Inari Medical) Brian Cox
10:48 AM Q&A From the Sharks Moderator: Tamir Wolf
11:00 AM Open Judge’s Discussion: Finalists Selection Moderators: Louis A. Cannon, Martin T. Rothman
11:30 AM Adjourn
11:40 AM Final Discussion/Decision (Top 2 Selected for the Award)
Wednesday, October 14, 2015
Main Arena III, Wednesday, Oct. 14 Accreditation: CME/CNE
Wednesday, October 14 8:00 AM - 2:00 PM Room: Moscone South, Esplanade Level, Main Arena
Plenary Session XVI. Live Cases 5: Aortic Valve and Structural Heart Disease 8:00 AM - 9:30 AM Live Case Moderator: Gregg W. Stone Live Case Co-Moderator: Michael J. Mack Live Case Discussants: Ted E. Feldman, Olaf Franzen, Philippe Généreux, Howard C. Herrmann, Susheel Kodali, Philippe Pibarot, Jeffrey J. Popma, Chet Rihal, Alec S. Vahanian, John G. Webb, Stephen G. Worthley Digital Moderator: Isaac George Digital Panelists: Karel T. Koch, Jean-Claude Laborde, Simon Redwood, Wilson Y. Szeto
8:00 AM Heart Center, University Hospital Bonn, Bonn, Germany Live Case Operators: Eberhard Grube, Christoph Hammerstingl, MD, Fritz Mellert, MD, Georg Nickenig, Jan-Malte Sinning, MD, Armin Welz, MD, Nikos Werner, MD
8:45 AM UniversitätsSpital Zürich, Zurich, Switzerland Live Case Operators: Bettex Dominique, MD, Francesco Maisano, Fabian Nietlispach, Michel Zuber, MD
Plenary Session XVII. Hot Topics 3: The Digital Health Revolution 9:30 AM - 10:05 AM Moderators: Peter J. Fitzgerald, Daniel Kraft, Martin B. Leon Digital Moderator: Roxana Mehran Digital Panelists: Kishore J. Harjai, Norman E. Lepor, Jack C. Lewin, Ivan C. Rokos Discussants: Anthony N. DeMaria, John G. Harold, Eric D. Peterson, Robert S. Schwartz, John A. Spertus, Eric J. Topol, Paul G. Yock
9:30 AM KEYNOTE LECTURE: How the Digital Health Revolution Will Change Our Lives in the Future! Eric J. Topol
9:50 AM Roundtable Discussion With Audience Q&A
Plenary Session XVIII. Clinically Oriented Case-Based Tutorials 3: “Stable” Vascular Disease 10:05 AM - 10:45 AM Moderators: William A. Gray, Gregg W. Stone Digital Moderator: D. Christopher Metzger Digital Panelists: Sripal Bangalore, Frederick Feit, Dmitriy N. Feldman, J. A. Mustapha Discussants: Bernard De Bruyne, Lawrence A. Garcia, Pedro A. Lemos, David J. Maron, Sahil A. Parikh, Vincent J. Pompili, Kenneth Rosenfield, Robert M. Schainfeld
10:05 AM Stable CAD With Substantial Ischemia and No-to-Mild Symptoms: Initial Revascularization vs Medical Therapy Case Presenter: Sripal Bangalore
10:10 AM Stable CAD With Substantial Ischemia and No-to-Mild Symptoms: Initial Revascularization vs Medical Therapy – Focused Commentary Commentator: Kimberly A. Skelding
10:15 AM Roundtable Discussion With Audience Q&A
10:25 AM When and How to Treat a Claudicant With an Occluded SFA Case Presenter: Herbert D. Aronow
10:30 AM When and How to Treat a Claudicant With an Occluded SFA – Focused Commentary Commentator: Michael R. Jaff
10:35 AM Roundtable Discussion With Audience Q&A
Plenary Session XIX. Master Operator Award 10:45 AM - 11:00 AM Moderators: Martin B. Leon, Gregg W. Stone
10:45 AM TCT 2015 Geoffrey O. Hartzler Master Operator Award Award Presenters: Martin B. Leon, Gregg W. Stone Award Recipient: Paul S. Teirstein
Plenary Session XX. Late-Breaking Clinical Trials 3: Co-sponsored by JAMA 11:00 AM - 12:00 PM Moderators: Eric D. Peterson, Gregg W. Stone Digital Moderator: Sripal Bangalore Digital Panelists: Christoph A. Kaiser, Petr Kala, Jens Flensted Lassen, Leif Thuesen Discussants: Aloke V. Finn, Upendra Kaul, Gregory Mishkel, Tullio Palmerini, Sigmund Silber, Giulio G. Stefanini, Stephen G. Worthley, Bo Xu, Adam J. de Belder, Clemens von Birgelen
11:00 AM JAMA Cardiology Eric D. Peterson
11:05 AM LEADERS FREE: A Prospective, Double-blind Randomized Trial of a Polymer-Free Biolimus-Eluting Stent Versus Bare Metal Stents in Patients With Coronary Artery Disease at High Risk for Bleeding Philip M. Urban
11:12 AM Roundtable Discussion With Audience Q&A
11:27 AM TUXEDO: A Prospective Randomized Trial of Paclitaxel-Eluting vs Everolimus-Eluting Stents in Diabetic Patients With Coronary Artery Disease Upendra Kaul
11:37 AM Roundtable Discussion With Audience Q&A
11:44 AM PANDA III: A Prospective Randomized Trial of 2 Sirolimus-Eluting Bioresorbable- Polymer–Based Metallic Stents With Varying Elution and Absorption Kinetics Bo Xu
11:54 AM Roundtable Discussion With Audience Q&A
Plenary Session XXI. First Report Investigations 3 12:00 PM - 12:30 PM Moderators: Fernando Alfonso, Pieter R. Stella Digital Moderator: Robert A. Byrne Digital Panelists: Mark C. Bates, Christopher Irobunda, Christopher D. Owens, Gunnar Tepe Discussants: Edoardo Camenzind, YunDai Chen, Roger Gammon, Gary Gershony, B.K. Goyal, John R. Laird Jr, Bruno Scheller, Goran Stankovic, Thomas Zeller
12:00 PM ISAR-DESIRE 4: A Prospective Randomized Trial of Plaque Modification With a Scoring Balloon During Drug-Coated Balloon Treatment of Coronary In-Stent Restenosis Robert A. Byrne
12:08 PM Roundtable Discussion With Audience Q&A
12:15 PM IN.PACT SFA: A Prospective Randomized Trial of a Drug-Coated Balloon for Femoropopliteal Lesions – Two-Year Outcomes John R. Laird Jr
12:23 PM Roundtable Discussion With Audience Q&A
Plenary Session XXII. Live Cases 6: Valve and Structural Heart Disease and Complex and High-Risk Interventions 12:30 PM - 2:00 PM Live Case Moderator: Martin B. Leon Live Case Co-Moderators: Barry D. Rutherford, Didier Tchetche Live Case Discussants: Colin M. Barker, Jacques J. Koolen, Jan Kovac, Axel Linke, G. Burkhard Mackensen, Massimo Napodano, Masahiko Ochiai, Augusto D. Pichard, Richard Smalling, Gabor Sutsch Digital Moderator: Michael J. Cowley Digital Panelists: Peter C. Block, Tony J. DeMartini, Vincent J. Pompili, Gerald S. Werner
12:30 PM Henry Ford Health System, Detroit, MI: Transcatheter Mitral Valve Replacement Live Case Operators: Khaldoon Alaswad, MD, Marvin Eng, MD, Adam B. Greenbaum, Robert J. Lederman, William W. O'Neill, Gaetano Paone, MD, Dee Dee Wang, MD
1:15 PM Belfast Health and Social Care Trust, Belfast, Ireland: CHIP Live Case Operators: Colm Hanratty, James C. Spratt, Simon J. Walsh
Coronary Theater III, Wednesday, Oct. 14 Accreditation: CME/CNE
Wednesday, October 14 8:00 AM - 12:00 PM Room: Moscone North, Lower Level, Hall D
Session I. Live Cases: Complex and High-Risk Interventions 8:00 AM - 10:00 AM Live Case Moderator: Emmanouil S. Brilakis Live Case Co-Moderator: Manish A. Parikh Live Case Discussants: Mohamed Abdel-Wahab, Adrian P. Banning, Thomas Engstroem, Dietmar H. Glogar, B.K. Goyal, Jonathan M. Hill, Manesh R. Patel, Tanveer Rab, Robert W. Yeh Digital Moderator: Srihari S. Naidu Digital Panelists: Alaide Chieffo, Vijay Kunadian, George W. Vetrovec
8:00 AM Henry Ford Health System, Detroit, MI Live Case Operators: Marvin Eng, MD, Adam B. Greenbaum, Robert J. Lederman, William W. O'Neill, Gaetano Paone, MD, Dee Dee Wang, MD Khaldoon Alswad, MD
9:00 AM Belfast Health and Social Care Trust, Belfast, Ireland Live Case Operators: Colm Hanratty, Simon J. Walsh Live Case Guest Operator: James C. Spratt
Session II. Live Cases: Complex and High-Risk Interventions 10:00 AM - 12:00 PM Live Case Moderator: Ajay J. Kirtane Live Case Co-Moderator: Navin K. Kapur Live Case Discussants: Yaron Almagor, Kevin J. Beatt, Michael J. Cowley, Simon R. Dixon, Aly El Banayosy, John M. Lasala, Jorge H. Leguizamon, Gert Richardt, Robert-Jan van Geuns Digital Moderator: Ehtisham Mahmud Digital Panelists: Germano Di Sciascio, Sundeep Mishra, Michael Mooney, Richard Smalling
10:00 AM Henry Ford Health System, Detroit, MI Live Case Operators: Marvin Eng, MD, Adam B. Greenbaum, Robert J. Lederman, William W. O'Neill, Gaetano Paone, MD, Dee Dee Wang, MD Khaldoon Alaswad, MD
11:00 AM Belfast Health and Social Care Trust, Belfast, Ireland Live Case Operators: Colm Hanratty, James C. Spratt, Simon J. Walsh
Structural Theater II, Wednesday, Oct. 14 Accreditation: CME/CNE
Wednesday, October 14 8:00 AM - 12:00 PM Room: Moscone North, Lower Level, Hall D
Session I. Live Cases: Heart Failure, Mitral, and Tricuspid Valve Interventions 8:00 AM - 10:00 AM Live Case Moderator: Scott Lim Live Case Co-Moderator: Joachim Schofer Live Case Discussants: Vasilis Babaliaros, Steven R. Bailey, Joost Daemen, Hans R. Figulla, Jai-Wun Park, Hendrik Treede, Marina Urena, Eric Van Belle, David X. Zhao Digital Moderator: Zoltan G. Turi Digital Panelists: Eric Horlick, Nicolas M. Van Mieghem, Olaf Wendler, David A. Wood
8:00 AM Quebec Heart and Lung Institute-Laval University, Quebec, Canada Live Case Operators: Sebastien Bergeron, Mathieu Bernier, Jean-Michel Paradis, Josep Rodés-Cabau
9:00 AM Heart Center, University Hospital Bonn, Bonn, Germany Live Case Operators: Eberhard Grube, Christoph Hammerstingl, Fritz Mellert, Georg Nickenig, Armin Welz, Nikos Werner
Session II. Live Cases: Mitral Valve Interventions and Left Atrial Appendage Closure 10:00 AM - 12:00 PM Live Case Moderator: Mark Reisman Live Case Co-Moderator: Matthew J. Price Live Case Discussants: Valerian Fernandes, Steven L. Goldberg, Clifford J. Kavinsky, Peter M. Pollak, Teguh Santoso, Jacqueline Saw, Gerhard C. Schuler, Giuseppe Tarantini, Steven J. Yakubov Digital Moderator: Samir R. Kapadia Digital Panelists: Carmelo Grasso, Chad Kliger, Randall J. Lee, Paul Vermeersch
10:00 AM Quebec Heart and Lung Institute-Laval University, Quebec, Canada Live Case Operators: Sebastien Bergeron, MD, Mathieu Bernier, MD, Gilles O'Hara, MD, Josep Rodés-Cabau
11:00 AM UniversitätsSpital Zürich, Zürich, Switzerland Live Case Operators: Bettex Dominique, MD, Francesco Maisano, Fabian Nietlispach, Michel Zuber, MD
TCT 2015 Exhibit Hall, Wednesday, Oct. 14 Accreditation: none
Wednesday, October 14 9:00 AM - 2:00 PM Room: Moscone South, Lower Level
The Exhibit Hall is the place to learn, explore, network, and take a break during TCT. More than 120 booths fill the large hall with the latest cutting-edge products and services selected just for you. 9:00 AM - 2:00 PM
9:00 AM Exhibit Hall
Atrial Fibrillation Management (With and Without PCI): Decisions and Dilemmas Accreditation: CME/CNE
Wednesday, October 14 2:00 PM - 6:00 PM Room: Moscone West, 2nd Floor, Room 2014 - 2018
Session I. Update on Data Emanating From Clinical Trials of Factor IIa and Xa Inhibition in Atrial Fibrillation 2:00 PM - 3:20 PM Moderators: Lisa K. Jennings, Matthew T. Roe Discussants: Aung Myat, Manesh R. Patel, Pascal Vranckx
2:00 PM Dabigatran: Analysis of Efficacy, Safety, and Special Considerations (Including Reversal Agents) Pascal Vranckx
2:15 PM Roundtable Discussion With Audience Q&A
2:20 PM Apixaban: Analysis of Efficacy, Safety, and Special Considerations Matthew T. Roe
2:32 PM Roundtable Discussion With Audience Q&A
2:36 PM Rivaroxaban: Analysis of Efficacy, Safety, and Special Considerations Manesh R. Patel
2:48 PM Roundtable Discussion With Audience Q&A
2:52 PM Edoxaban: Analysis of Efficacy, Safety, and Special Considerations
3:04 PM Roundtable Discussion With Audience Q&A
3:08 PM Reversal Agents for Factor Xa Inhibitors Lisa K. Jennings
3:16 PM Roundtable Discussion With Audience Q&A
Session II. Management of the Patient With Atrial Fibrillation and Coronary Artery Disease (ACS and PCI) 3:20 PM - 4:40 PM Moderator: Pascal Vranckx Discussants: Deepak L. Bhatt, Renato D. Lopes, Roxana Mehran
3:20 PM Can We Drop Aspirin? Pharmacodynamic Insights on Adding an Oral Anticoagulant to Antiplatelet Therapy With and Without Aspirin Freek W.A. Verheugt
3:35 PM Roundtable Discussion With Audience Q&A
3:40 PM A Trial of Apixaban in Patients With Atrial Fibrillation and ACS/PCI: Design, Rationale, and Status Renato D. Lopes
3:55 PM Roundtable Discussion With Audience Q&A
4:00 PM The RE-DUAL PCI Trial (Dabigatran in Patients With ACS and Atrial Fibrillation): Design, Rationale, and Status Deepak L. Bhatt
4:15 PM Roundtable Discussion With Audience Q&A
4:20 PM The PIONEER Trial (Rivaroxaban in Patients With ACS and Atrial Fibrillation): Design, Rationale, and Status Roxana Mehran
4:35 PM Roundtable Discussion With Audience Q&A
Session III. Device Management, Controversies, and Practical Guidance in the Management of Atrial Fibrillation 4:40 PM - 6:00 PM Moderator: Gerhard C. Schuler Discussants: C. Michael Gibson, Randall J. Lee, Matthew J. Price, Freek W.A. Verheugt
4:40 PM Alternatives to Anticoagulation: Left Atrial Appendage Occlusion Devices Matthew J. Price 4:52 PM Roundtable Discussion With Audience Q&A
4:55 PM Device-Detected, Subclinical Atrial Fibrillation: Now What? Freek W.A. Verheugt
5:07 PM Roundtable Discussion With Audience Q&A
5:10 PM Management of the Patient Undergoing Cardioversion or Catheter-Based Ablation TBA
5:22 PM Roundtable Discussion With Audience Q&A
5:25 PM Considerations Regarding Renal Function in the Patient With Atrial Fibrillation C. Michael Gibson
5:37 PM Roundtable Discussion With Audience Q&A
5:40 PM Putting It All Together: How to Manage the Patient With Atrial Fibrillation Undergoing PCI Matthew J. Price
5:52 PM Roundtable Discussion With Audience Q&A
Bioresorbable Vascular Scaffolds, Part 1 Accreditation: CME
Wednesday, October 14 2:00 PM - 6:00 PM Room: Moscone West, 3rd Floor, Room 3001 - 3005
Session I. Emerging Understanding of BRS Fundamentals 2:00 PM - 3:06 PM Moderators: Elazer R. Edelman, Juan F. Granada Discussants: Greg L. Kaluza, John A. Ormiston, Patrick W. Serruys, Renu Virmani, Ron Waksman, Nick E. J. West
2:00 PM Biomechanical Implications of Scaffold Design on Vascular Biology and Healing Elazer R. Edelman
2:07 PM Effects of Polymer Manufacturing Processes on the Mechanical Properties of BRS Patrick W. Serruys
2:14 PM Core Differences Between Degradable Metals and Polymers in Mechanical Strength, Mode of Absorption, Healing, and More Ron Waksman
2:21 PM What Have We Learned About BRS From Healthy Animal Models? Renu Virmani 2:28 PM What Have We Learned About BRS From Atherosclerotic Animal Models? Greg L. Kaluza
2:35 PM BRS Mechanical Properties, Conformability, and Other Insights From Bench Studies Nicolas Foin
2:42 PM Independent Bench Comparison of Different Bioresorbable Scaffolds John A. Ormiston
2:49 PM BRS Vasomotion and Microcirculatory Function Update Nick E. J. West
2:56 PM Roundtable Discussion With Audience Q&A: What Do These Data Mean for the Treatment of Patients Today?
Session II. An Avalanche of New ABSORB Data 3:06 PM - 5:00 PM Moderators: Stephen G. Ellis, Patrick W. Serruys Discussants: Run-Lin Gao, Dean J. Kereiakes, Takeshi Kimura, Detlef G. Mathey, Giulio G. Stefanini, Gregg W. Stone
3:06 PM Featured Lecture: First Report of the 5-Year Cohort B Multimodality Imaging Results (And My Clinical Predictions Based on These Findings) Patrick W. Serruys
3:18 PM Comparative Outcomes of Absorb BVS in the Real-world: Insights From GHOST-EU and XIENCE V USA Davide Capodanno
3:25 PM New Randomized Trial Data (1-Year Outcomes): ABSORB Japan (ESC Late-Breaking Trial Results and Beyond) Takeshi Kimura
3:35 PM New Randomized Trial Data (1-Year Outcomes): ABSORB China (TCT Late-Breaking Clinical Trial Results and Beyond) Run-Lin Gao
3:45 PM New Randomized Trial Data (1-Year Outcomes): ABSORB III (TCT Late-Breaking Clinical Trial Results and Beyond) Dean J. Kereiakes
3:57 PM Featured Lecture: One-Year Patient-Level Pooled Meta-analysis From 4 ABSORB Trials in 3389 Randomized Patients Gregg W. Stone
4:09 PM New Randomized Trial Data (1-Year Outcomes): TROFI II Patrick W. Serruys
4:19 PM New Randomized Trial Data (2-Year Outcomes): ABSORB II (TCT First Report Investigation Results and Beyond) Bernard R. Chevalier 4:29 PM New Randomized Trial Data (2-Year Outcomes): EVERBIO II Serban Puricel
4:39 PM Assessing Whether Superiority Exists: Design, Rationale, and Status of ABSORB IV Gregg W. Stone
4:45 PM Roundtable Discussion With Audience Q&A: What Does This Data Mean for the Treatment of Patients Today?
Session III. BRS Complications, Failure Modes, and Their Prevention 5:00 PM - 6:00 PM Moderators: Detlef G. Mathey, Nicolas M. Van Mieghem Discussants: Bernard R. Chevalier, Carlo Di Mario, Hector M. Garcia-Garcia, Michael Joner, Julinda Mehilli, Robert C. Welsh
5:00 PM Incidence and Predictors of BRS Scaffold Thrombosis Luis Ortega Paz, MD
5:07 PM Very Late (>1 Year) Scaffold Thrombosis After BRS Lorenz Raber
5:14 PM Neoatherosclerosis After BRS May Occur Corrado Tamburino
5:19 PM Imaging Insights Into BRS Failure Modes (Thrombosis and Restenosis) Yoshinobu Onuma
5:26 PM Tips and Tricks to Optimize Acute and Long-term BRS Outcomes Antonio Colombo
5:36 PM Scaffold Expansion as the Essential Requirement to Prevent BRS Failure Stephan Achenbach
5:43 PM The Critical Role of Lesion Preparation for BRS: Effects of Plaque Morphology, Components, and Novel Devices Giulio Guagliumi
5:50 PM Roundtable Discussion With Audience Q&A
Carotid and Stroke Intervention: State of the Art Accreditation: CME/CNE
Wednesday, October 14 2:00 PM - 6:00 PM Room: Moscone West, 2nd Floor, Room 2006 - 2008 Session I. Carotid Disease and Treatment 2:00 PM - 4:03 PM Moderators: William A. Gray, D. Christopher Metzger Discussants: Herbert D. Aronow, Klaus D. Mathias, Piotr Musialek, Juan C. Parodi, Bernhard Reimers, Gary S. Roubin
2:00 PM Beyond Stenosis Severity: Top 5 Important Duplex Characteristics to Identify in the Patient With Carotid Disease Jan Sloves
2:12 PM Roundtable Discussion With Audience Q&A
2:16 PM What Are the Hard Data Regarding the Impact of Medical Therapy on Stroke Prevention in Established Severe Carotid Stenosis? Klaus D. Mathias
2:28 PM Roundtable Discussion With Audience Q&A
2:32 PM Pre-debate Vote: Is CREST-2 a Worthwhile Use of Precious Resources? Poll Moderators: William A. Gray, D. Christopher Metzger
2:34 PM Debate: Is CREST-2 a Worthwhile Use of Precious Resources? The CREST-2 Trial Is the Right Trial at the Right Time! Gary S. Roubin
2:41 PM Debate: Is CREST-2 a Worthwhile Use of Precious Resources? Another Failed NIH- Funded Study: CREST-2 Is CORAL Redux (or Worse)! D. Christopher Metzger
2:48 PM Roundtable Discussion With Audience Q&A
2:55 PM Post-debate Vote (Who Won?): Is CREST-2 a Worthwhile Use of Precious Resources? Poll Moderators: William A. Gray, D. Christopher Metzger
2:57 PM Update on the ACST-2 Trial: Early Outcomes and Perspectives on the Field From Across the Pond Bernhard Reimers
3:07 PM Roundtable Discussion With Audience Q&A
3:10 PM Mesh-Covered Stents for Carotid Intervention: Rationale, Device Designs, Imaging, and Data to Date Piotr Musialek
3:20 PM Roundtable Discussion With Audience Q&A
3:23 PM Pre-debate Vote: Is Transcarotid Artery Revascularization a Revolutionary Advance? Poll Moderators: William A. Gray, D. Christopher Metzger
3:25 PM Debate: Is Transcarotid Artery Revascularization a Revolutionary Advance? Yes, It Is a Game Changer for Both Outcomes and Adoption of Carotid Stenting! Christopher J. Kwolek
3:31 PM Debate: Is Transcarotid Artery Revascularization a Revolutionary Advance? No, It Is Too Complex and There Is No Advantage for the Patient! Bernhard Reimers
3:37 PM Roundtable Discussion With Audience Q&A
3:41 PM Post-debate Vote (Who Won?): Is Transcarotid Artery Revascularization a Revolutionary Advance? Poll Moderators: William A. Gray, D. Christopher Metzger
3:43 PM Pre-debate Vote: Should Carotid Stenting Volume Requirements Be Markedly Decreased or Eliminated? Poll Moderators: William A. Gray, D. Christopher Metzger
3:45 PM Debate: Should Carotid Stenting Volume Requirements Be Markedly Decreased or Eliminated? Yes, Given the Drop in Activity Resulting From a Lack of Reimbursement and No Data Showing They Are Necessary! Gary S. Roubin
3:51 PM Debate: Should Carotid Stenting Volume Requirements Be Markedly Decreased or Eliminated? Nonsense, Patient Safety Above All Else! Herbert D. Aronow
3:57 PM Roundtable Discussion With Audience Q&A
4:01 PM Post-debate Vote (Who Won?): Should Carotid Stenting Volume Requirements Be Markedly Decreased or Eliminated? Poll Moderators: William A. Gray, D. Christopher Metzger
Session II. Endovascular Intervention for Acute Stroke: The Dawn of a New Era for Patients and Cardiologists Alike? 4:03 PM - 6:00 PM Moderators: Leo Nelson Hopkins, Tudor G. Jovin Discussants: Alex Abou-Chebl, Philip M. Meyers, Mark H. Wholey, Joshua Z. Willey
4:03 PM Featured Lecture: Endovascular Stroke Trials Go From Sorry to Sensational Practically Overnight – Results, Analysis, and Implications for the Field Philip M. Meyers
4:18 PM Roundtable Discussion With Audience Q&A
4:23 PM Overview of Stroke: Etiologies, Demographics, Syndromes, and Outcomes by the Rankin Scale Alex Abou-Chebl
4:35 PM Roundtable Discussion With Audience Q&A
4:38 PM Defining the Elements, Workings, and Challenges of Developing a Truly Comprehensive Stroke Center Leo Nelson Hopkins
4:50 PM Roundtable Discussion With Audience Q&A
4:53 PM Integrating Imaging Into the Clinical Decision Making in Acute Stroke Tudor G. Jovin 5:03 PM Roundtable Discussion With Audience Q&A
5:06 PM The Role of TPA in the Updated Stroke Approach Joshua Z. Willey
5:16 PM Roundtable Discussion With Audience Q&A
5:19 PM Interventional Manpower and Logistics in the New Era of Stroke Therapy: Should Cardiology Integrate Into the Stroke Team? If so, How? Klaus D. Mathias
5:29 PM What Cardiologists Need to Know Before Becoming Stroke Interventionalists I: Basic Cerebrovascular Anatomy and Physiology and Differences Between the Cerebral and Coronary Arteries in Stroke Mark H. Wholey
5:39 PM What Cardiologists Need to Know Before Becoming Stroke Interventionalists II: How to Use Modern Neuro-Interventional Tools and Techniques to Optimize Stroke Outcomes Alex Abou-Chebl
5:49 PM Prerecorded Case: Acute Stroke Intervention Tudor G. Jovin
5:55 PM Roundtable Discussion With Audience Q&A
CHIP: Calcified Lesions, Multivessel/Diffuse Disease, Vein Grafts, Shock, and More Accreditation: CME/CNE
Wednesday, October 14 2:00 PM - 6:00 PM Room: Moscone West, 2nd Floor, Room 2001 - 2005
Session I. An Introduction to CHIP 2:00 PM - 2:28 PM Moderators: Philippe Généreux, Brij Maini Discussants: Ajay J. Kirtane, John M. Lasala, Pedro R. Moreno, Holger Thiele, Robert W. Yeh
2:00 PM CHIP: Overview of an Unmet Need Ajay J. Kirtane
2:08 PM High-Risk Intervention: Risk for the Operators or the Patient? Reconciling Risk Scores, Appropriateness, Public Reporting, and Institutional Needs Robert W. Yeh
2:18 PM Roundtable Discussion With Audience Q&A Session II. High-Risk PCI, Part 1: The Patient With LV Dysfunction 2:28 PM - 3:30 PM Moderators: Robert O. Bonow, Ajay J. Kirtane Discussants: Adriano Caixeta, Thomas Engstroem, Mark Goldberger, Jeffrey W. Moses, Sunil V. Rao, Joseph F. Sabik, Grayson H. Wheatley
2:28 PM Case Presentation at Baseline: MVD With LV Dysfunction With Intermediate SYNTAX Score Case Presenter: Adriano Caixeta
2:31 PM Evidence Review: Revascularization in LV Dysfunction After STICH – Who Might Benefit? Robert O. Bonow
2:41 PM I Would Treat This Patient Conservatively (Medications First) Mark Goldberger
2:46 PM I Would Treat This Patient With Surgery Joseph F. Sabik
2:51 PM I Would Treat This Patient With PCI Ajay J. Kirtane
2:56 PM Case Presentation: How We Treated MVD With LV Dysfunction With Intermediate SYNTAX Score Case Presenter: Adriano Caixeta
2:59 PM The Role of Hemodynamic Support in Nonemergent PCI and LV Dysfunction Brij Maini
3:07 PM Temporary Cardiac Support During High-Risk PCI: HeartMate PHP and the SHIELD I Study David E. Kandzari
3:12 PM The Role of the Life Vest, ICDs, and BiV Pacing in Patients With LV Dysfunction William T. Abraham
3:20 PM Roundtable Discussion With Audience Q&A
Session III. High-Risk PCI, Part 2: Cardiogenic Shock 3:30 PM - 4:40 PM Moderators: Tanveer Rab, Holger Thiele Discussants: Aly El Banayosy, Vijay Kunadian, Michel R. Le May, Sundeep Mishra, Pedro R. Moreno, Sunil V. Rao
3:30 PM The Spectrum of Hemodynamic Support Options for Shock Vladimir Dzavik
3:40 PM Pre-debate Vote: What Support Device Should Most Frequently Be Used in Cardiogenic Shock? Poll Moderators: Tanveer Rab, Holger Thiele 3:42 PM What Support Device Should Most Frequently Be Used in Cardiogenic Shock? Impella for Most! Jose P.S. Henriques
3:49 PM Debate: What Support Device Should Most Frequently Be Used in Cardiogenic Shock? IABP Is Still Frontline! Sunil V. Rao
3:56 PM Debate: What Support Device Should Most Frequently Be Used in Cardiogenic Shock? ECMO for True Shock! Aly El Banayosy
4:03 PM Roundtable Discussion With Audience Q&A
4:08 PM Post-debate Vote (Who Won?): What Support Device Should Most Frequently Be Used in Cardiogenic Shock? Poll Moderators: Tanveer Rab, Holger Thiele
4:10 PM Escalation Therapies and RV Dysfunction: New Opportunities Navin K. Kapur
4:17 PM The Role (and Timing) of Complete Revascularization in AMI and Cardiogenic Shock Holger Thiele
4:23 PM Just How Effective Is Hypothermia in Cardiac Arrest? Michel R. Le May
4:30 PM Roundtable Discussion With Audience Q&A
Session IV. Anatomic and Lesion-Specific Challenges 4:40 PM - 6:00 PM Moderators: Jeffrey W. Moses, Erick Schampaert Discussants: Mohamed Abdel-Wahab, Nabil Dib, Philippe Généreux, Dimitri Karmpaliotis, Gert Richardt
4:40 PM Sorting Through Revascularization Choices in Left Main and Multivessel Disease: A Practical Approach Jeffrey W. Moses
4:49 PM CTO in Patients With Left Main and Multivessel Disease: Why and When to Treat Barry D. Rutherford
4:57 PM Roundtable Discussion With Audience Q&A
5:05 PM Atheroablation: Current Technologies and Techniques Mohamed Abdel-Wahab
5:13 PM Pre-debate Vote: Should Atheroablation Be Used More Often Than It Is Now (< 5% of Cases)? Poll Moderators: Ajay J. Kirtane, Erick Schampaert
5:15 PM Debate: Should Atheroablation Be Used More Often? No, the Present Evidence Says It Should Be Used Sparingly! Gert Richardt
5:22 PM Debate: Should Atheroablation Be Used More Often? Yes, Atheroablation Is Underutilized! Nabil Dib
5:29 PM Roundtable Discussion With Audience Q&A
5:34 PM Post-debate Vote (Who Won?): Should Atheroablation Be Used More Often Than Now (< 5% of Cases)? Poll Moderator: Erick Schampaert
5:36 PM SVG Intervention: Is Distal Protection Still Needed? And Should We Always Do the Native Vessel Instead? Dimitri Karmpaliotis
5:44 PM New Approaches for Diffuse Disease: DEB, BRS, and Beyond Giuseppe Tarantini
5:52 PM Roundtable Discussion With Audience Q&A
Interventional Heart Failure Therapies, Part 2 Accreditation: none
Wednesday, October 14 2:00 PM - 5:45 PM Room: Moscone West, 3rd Floor, Room 3006 - 3008
Session VI. Neuromodulation Devices for Heart Failure 2:00 PM - 2:55 PM Moderators: Daniel Burkhoff, Ileana L. Pina Discussants: William T. Abraham, Lorenzo DiCarlo, Jochen Müller-Ehmsen, Marvin J. Slepian, Guillermo Torre-Amione
2:00 PM Autonomic Regulation Therapy for HF Lorenzo DiCarlo
2:10 PM Spinal Cord Stimulation Guillermo Torre-Amione
2:20 PM CVRx Jochen Müller-Ehmsen
2:30 PM Impulse Dynamics William T. Abraham
2:40 PM Roundtable Discussion With Audience Q&A Session VII. Acute and Durable Mechanical Circulatory Support 2:55 PM - 5:10 PM Moderators: Valluvan Jeevanandam, Ulrich P. Jorde Discussants: Jonathan M. Hill, Navin K. Kapur, Biswajit Kar, Nir Uriel
2:55 PM Key Issues for Management of Durable VAD Patients Nir Uriel
3:10 PM LV to Aorta Pumping: Impella Jonathan M. Hill
3:20 PM LV to Aorta Pumping: HeartMate PHP Ulrich P. Jorde
3:30 PM Right Heart Support: Impella RP and TandemHeart Navin K. Kapur
3:40 PM LA to Aorta Pumping: TandemHeart Biswajit Kar
3:50 PM NuPulse iVAS - A Minimally Invasive Advanced CHF Device Valluvan Jeevanandam
4:00 PM Durable Ventricular Assist Devices: Current and Next-Generation Devices and Implantation Techniques Ulrich P. Jorde
4:10 PM Latest Innovations in ECMO and Escalation of Therapy Jonathan M. Hill
4:20 PM Roundtable Discussion With Audience Q&A
4:40 PM Case Introduction: A Decompensated Patient With Heart Failure and Hypotension Ulrich P. Jorde
4:45 PM How Should We Treat This Patient: Roundtable Discussion With Audience Q&A
4:55 PM Case Resolution: How Did We Treat Our Patient? Ulrich P. Jorde
5:00 PM CPulse Dimitrios Georgakopoulos
Session VIII. Therapies to "Cure" Heart Failure 5:10 PM - 5:45 PM Moderators: Henricus J. Duckers, Bernard J. Gersh Discussants: Thomas Engstroem, James E. Udelson, Wojtek Wojakowski
5:10 PM Gene Therapy for CHF Gary L. Schaer
5:20 PM Cell Therapy for CHF Timothy D. Henry
5:30 PM Roundtable Discussion With Audience Q&A
The Left Main and Bifurcation Summit, Part 1: Non–Left Main Bifurcations Accreditation: CME/CNE
Wednesday, October 14 2:00 PM - 6:12 PM Room: Moscone West, 2nd Floor,Room 2020 - 2024
Session I. Bifurcation Lesions: New Insights With Metallic Stent Treatment 2:00 PM - 3:27 PM Moderators: Antonio L. Bartorelli, Yves R. Louvard Discussants: Yaron Almagor, Vinay K. Bahl, Olivier F. Bertrand, Jacek Legutko, Issam D. Moussa, Adam J. de Belder
2:00 PM New Lessons From the Bench Nicolas Foin
2:07 PM Bifurcation Lesions as You Have Never Seen Them Before: Insights From the Visible Heart Project Francesco Burzotta
2:14 PM Roundtable Discussion With Audience Q&A
2:17 PM Plaque Shift vs Carina Shift: Which Is It, and Does It Matter? Hyeon-Cheol Gwon
2:24 PM Roundtable Discussion With Audience Q&A
2:26 PM Is Side-Branch Predilatation Prior to Provisional Stenting Helpful or Harmful? Manuel Pan
2:33 PM Roundtable Discussion With Audience Q&A
2:35 PM Has the Proximal Optimization Technique (POT) Become Essential? Here’s Why Massoud A. Leesar
2:42 PM Re-POT: Description and Comparative Results in Provisional Bifurcation Stenting Gerard Finet
2:49 PM Roundtable Discussion With Audience Q&A
2:52 PM FFR Assessment of the Side Branch: From Theory (Yes) to Practice (Not so Much) Shao-Liang Chen 2:59 PM Roundtable Discussion With Audience Q&A
3:01 PM One vs 2 Stents: Is the Debate Over? Terje K. Steigen
3:08 PM Impact of Second-Generation DES on the 1 vs 2 Stent Debate Hyo-Soo Kim
3:15 PM Roundtable Discussion With Audience Q&A
3:18 PM Kissing Balloon Inflation: An Essential Review Bernard R. Chevalier
3:25 PM Roundtable Discussion With Audience Q&A
Session II. Non–Left Main Bifurcations: Technical Forum 3:27 PM - 4:33 PM Moderators: Shao-Liang Chen, Antonio Colombo Discussants: Remo Albiero, Robert J. Applegate, Vinay K. Bahl, Robert T Gerber, Gary Gershony, Gennaro Sardella
3:27 PM How to Overcome: Difficult Side Branch Access Before and After Stent Implantation Thierry Lefevre
3:34 PM Utility of Intravascular Imaging Guidance of Bifurcation PCI Ning Guo
3:41 PM Roundtable Discussion With Audience Q&A
3:44 PM How, When, and Why to Perform: Provisional Side Branch Stenting (Step-by-Step) Jens Flensted Lassen
3:51 PM How, Why, and When to Perform: T-Stenting and TAP (Step-by-Step) Ioannis Iakovou
3:58 PM How, Why, and When to Perform: Culotte Stenting (Step-by-Step) Carlo Di Mario
4:05 PM How, Why and, When to Perform: Mini-Crush Stenting (Step-by-Step) Alaide Chieffo
4:12 PM How, Why, and When to Perform: DK Crush (Step-by-Step) James B. Hermiller Jr
4:19 PM Matching the 2-Stent Technique to the Bifurcation Lesion Morphology Vladimir Dzavik
4:26 PM Roundtable Discussion With Audience Q&A
Session III. Non–Left Main Bifurcations: The New Data 4:33 PM - 5:27 PM Moderators: Thierry Lefevre, Leif Thuesen Discussants: Adrian P. Banning, Peter L Duffy, Dietmar H. Glogar, Jacek Legutko, Bernhard Reimers, Jamil Abdalla Saad
4:33 PM Nordic IV Study: One vs 2 Stents Jens Flensted Lassen
4:40 PM Roundtable Discussion With Audience Q&A
4:42 PM EBC 2 Study: One vs 2 Stents for Large Side Branches David Hildick-Smith
4:49 PM Roundtable Discussion With Audience Q&A
4:51 PM New Insights From the COBIS Registry: Role of NC Balloons and More Hyeon-Cheol Gwon
4:58 PM Roundtable Discussion With Audience Q&A
5:00 PM Cross and Perfect Randomized Studies Young-Hak Kim
5:07 PM Roundtable Discussion With Audience Q&A
5:09 PM Nordic III 5-Year Results: To Kiss vs Not to Kiss Matti Jaakko Niemela
5:16 PM Roundtable Discussion With Audience Q&A
5:18 PM Five-Year BBC ONE Outcomes Nick Curzen
5:25 PM Roundtable Discussion With Audience Q&A
Session IV. Bioresorbable Scaffolds in Bifurcation Lesions 5:27 PM - 6:12 PM Moderators: Kenneth Chin, David G. Rizik Discussants: Arif Al Nooryani, Alaide Chieffo, Jose de Ribamar Costa Jr, Ioannis Iakovou, Manuel Pan, Ashok Seth
5:27 PM BRS in Bifurcations: Bench Insights John A. Ormiston
5:34 PM Roundtable Discussion With Audience Q&A
5:36 PM POT and Mini-Kiss (Snuggling) Using BRS in Bifurcations Azeem Latib
5:43 PM Roundtable Discussion With Audience Q&A
5:45 PM BRS in Bifurcations: GHOST Lessons Davide Capodanno 5:52 PM Roundtable Discussion With Audience Q&A
5:54 PM OCT-Guided BRS Implantation in Bifurcations Niels R. Holm
6:01 PM Roundtable Discussion With Audience Q&A
6:03 PM BRS in Bifurcations: Practical 2015 Recommendations (With Case Examples) Antonio Colombo
6:10 PM Roundtable Discussion With Audience Q&A
PFO Closure and Congenital Heart Disease in the Adult Accreditation: CME/CNE
Wednesday, October 14 2:00 PM - 6:00 PM Room: Moscone West, 3rd Floor,Room 3002 - 3004
Session I. PFO and Stroke Session 2:00 PM - 3:06 PM Moderators: John D. Carroll, Mark Reisman Discussants: Patrick A. Calvert, Roger J. Laham, Harsimran Sachdeva Singh, David E. Thaler, Nina C. Wunderlich
2:00 PM RESPECT: Long-term (Median >5 Years) Results, With an In-depth Analysis of the Lessons Learned John D. Carroll
2:10 PM Meta-analysis of PFO Stroke Trials David E. Thaler
2:20 PM Clinical Practice in 2015: When Closure Is and Is Not Justified Mark Reisman
2:28 PM Risk of Paradoxical Embolism With Pacemaker Leads Samir R. Kapadia
2:36 PM Update on the ROPE Study: Emerging Insights David E. Thaler
2:44 PM Poll 1 Poll Moderators: John D. Carroll, Mark Reisman
2:47 PM Poll 2 Poll Moderators: John D. Carroll, Mark Reisman 2:50 PM Roundtable Discussion With Audience Q&A
Session II. PFO Closure and Other Clinical Syndromes 3:06 PM - 4:10 PM Moderators: David Hildick-Smith, Jonathan M. Tobis Discussants: Lee N. Benson, Franz X. Kleber, John C. Messenger, Robert J. Sommer
3:06 PM PREMIUM Trial: Lessons Learned Jonathan M. Tobis
3:16 PM PRIMA Trial: Lessons Learned David Hildick-Smith
3:26 PM Are There Certain Patients for Whom PFO Closure for Migraine Should Now Be Considered Acceptable? Robert J. Sommer
3:34 PM Paradoxical Embolic Myocardial Infarction: Analysis of More Than 6500 Patients With AMI Franz X. Kleber
3:42 PM PFO and Hypoxemia: Patient Selection John C. Messenger
3:50 PM Poll 3 Poll Moderators: David Hildick-Smith, Jonathan M. Tobis
3:53 PM Poll 4 Poll Moderators: David Hildick-Smith, Jonathan M. Tobis
3:56 PM Roundtable Discussion With Audience Q&A
Session III. ASD and PFO Closure Devices in 2015 4:10 PM - 5:00 PM Moderators: David W.M. Muller, John F. Rhodes Discussants: Zahid Amin, Sameer Gafoor, Eric Horlick, Robert J. de Winter
4:10 PM GSO: Good-bye Helex John F. Rhodes
4:20 PM Acroredis, Iris Fit, and CARAG ASD Occluder Horst Sievert
4:30 PM The FDA-Mandated Postapproval Study of the Amplazter ASO Device Zahid Amin
4:40 PM Poll 5 Poll Moderators: Ziyad M. Hijazi, John F. Rhodes 4:43 PM Poll 6 Poll Moderators: Ziyad M. Hijazi, John F. Rhodes
4:46 PM Roundtable Discussion With Audience Q&A
Session IV. Other Adult Congenital Heart Disease Topics 5:00 PM - 6:00 PM Moderators: Ziyad M. Hijazi, Robert J. Sommer Discussants: Elchanan Bruckheimer, John P. Cheatham, Hans R. Figulla, Thomas K. Jones, Carlos Pedra, Lars Sondergaard
5:00 PM Melody, Edwards, and Venus Valves: Lessons Learned and Future Directions Thomas K. Jones
5:10 PM ADO II and Other Approaches to PDA Closure Lars Sondergaard
5:20 PM The State of the Art of Transcatheter Treatment of Aortic Coarctation in Adults John P. Cheatham
5:30 PM Paravalvular Leak Closure: New Devices and the State of the Art Ziyad M. Hijazi
5:40 PM Poll 7 Poll Moderators: Ziyad M. Hijazi, Robert J. Sommer
5:43 PM Poll 8 Poll Moderators: Ziyad M. Hijazi, Robert J. Sommer
5:46 PM Roundtable Discussion With Audience Q&A
Transcatheter Aortic Valve Therapies: Today and Tomorrow, Part 3 Accreditation: CME/CNE
Wednesday, October 14 2:00 PM - 6:00 PM Room: Moscone West, 3rd Floor, Room 3007 - 3011
Session VII. New TAVR Technology: TAVR Systems, Part 1 2:00 PM - 3:40 PM Moderators: Ariel Finkelstein, Ganesh Manoharan Discussants: Stephen J.D. Brecker, Isaac George, Azeem Latib, Scott Lim, Axel Linke, Raj Makkar, Ian T. Meredith, Vinod H. Thourani
2:00 PM FDA-Approved or US IDE Studies: EVOLUT R – Technical Specifications and Clinical Trial Results (CE Study and Available US Results) Jeffrey J. Popma
2:10 PM FDA-Approved or US IDE Studies: EVOLUT R – Procedural Considerations and Case Examples Stephen J.D. Brecker
2:17 PM Roundtable Discussion With Audience Q&A
2:20 PM FDA-Approved or US IDE Studies: SAPIEN 3 - Technical Specifications and Clinical Trial Results (CE Studies and PARTNER II S3HR and S3i) Susheel Kodali
2:30 PM FDA-Approved or US IDE Studies: SAPIEN 3 – Procedural Considerations and Case Examples Vinod H. Thourani
2:37 PM Roundtable Discussion With Audience Q&A
2:40 PM FDA-Approved or US IDE Studies: LOTUS – Technical Specifications and Clinical Trial Results (REPRISE Clinical Studies With FU) Ian T. Meredith
2:50 PM FDA-Approved or US IDE Studies: LOTUS – Procedural Considerations and Case Examples Ted E. Feldman
2:57 PM Roundtable Discussion With Audience Q&A
3:00 PM FDA-Approved or US IDE Studies: DIRECT FLOW – Technical Specifications and Clinical Trial Results (DISCOVER and SALUS Clinical Studies) Isaac George
3:10 PM FDA-Approved or US IDE Studies: DIRECT FLOW – Procedural Considerations and Case Examples Azeem Latib
3:17 PM Roundtable Discussion With Audience Q&A
3:20 PM FDA-Approved or US IDE Studies: PORTICO – Technical Specifications and Clinical Trial Results (CE Study and US Trial Updates) Raj Makkar
3:30 PM FDA-Approved or US IDE Studies: PORTICO – Procedural Considerations and Case Examples Ganesh Manoharan
3:37 PM Roundtable Discussion With Audience Q&A
Session VIII. New TAVR Technology: TAVR Systems, Part 2 3:40 PM - 5:05 PM Moderators: Martin B. Leon, Nicolo Piazza Discussants: Alexandre Abizaid, Anson Cheung, Isaac George, Christian Hengstenberg, Susheel Kodali, Helge Möllmann, Horst Sievert, Didier Tchetche, Hendrik Treede 3:40 PM CE-Approved or EU Studies: ACURATE – Technical Specifications and Clinical Trial Results (CE Study and Other EU Results) Helge Möllmann
3:50 PM CE-Approved or EU Studies: ACURATE – Procedural Considerations and Case Examples Alexandre Abizaid
3:57 PM New TAVR System: J-Valve – Technology Review and Clinical Update Anson Cheung
4:07 PM Roundtable Discussion With Audience Q&A
4:10 PM CE-Approved or EU Studies: CENTERA – Technology Review and Clinical Update Didier Tchetche
4:18 PM Roundtable Discussion With Audience Q&A
4:20 PM CE-Approved or EU Studies: JenaValve – Technology Review and Clinical Update (JUPITER Trials) Hendrik Treede
4:28 PM Roundtable Discussion With Audience Q&A
4:30 PM Early Stage New TAVR Systems: Trinity Valve – Technology Review and Clinical Update Christian Hengstenberg
4:35 PM Early Stage New TAVR Systems: Thubikar Valve – Technology Review and Clinical Update Susheel Kodali
4:40 PM CE-Approved or EU Studies: ENGAGER – Technology Review and Clinical Update Hendrik Treede
4:45 PM Early Stage New TAVR Systems: Valve Medical – Technology Review and Clinical Update Martin B. Leon
4:48 PM Roundtable Discussion With Audience Q&A
4:50 PM Early Stage New TAVR Systems: Venus A Valve – Technology Review and Clinical Update Horst Sievert
4:58 PM Roundtable Discussion With Audience Q&A
Session IX. New TAVR Technology: Accessory Devices 5:05 PM - 6:00 PM Moderators: Susheel Kodali, Axel Linke Discussants: Hemal Gada, Isaac George, Alexandra J. Lansky, Martin B. Leon, G. Burkhard Mackensen, Wesley R. Pedersen, Anna Sonia Petronio, Torsten P. Vahl 5:05 PM Cerebral Embolic Protection Devices: Sentinel Dual Filter Device – Technology Review and CLEAN-TAVI Results Axel Linke
5:15 PM Cerebral Embolic Protection Devices: Sentinel Dual Filter Device – Update of US Pivotal Clinical Trial Susheel Kodali
5:22 PM Cerebral Embolic Protection Devices: Triguard Deflector Device – Technology Review and DEFLECT III Results Alexandra J. Lansky
5:32 PM Roundtable Discussion With Audience Q&A
5:35 PM An Update of New Aortic Valvuloplasty and Valve Remodeling Technologies Martin B. Leon
5:43 PM Roundtable Discussion With Audience Q&A
5:45 PM Dedicated Guidewires for TAVR Wesley R. Pedersen
5:50 PM Novel Sheath Technology for TAVR Hemal Gada
5:55 PM Roundtable Discussion With Audience Q&A
Transcatheter Mitral Valve Therapies: Today and Tomorrow, Part 3 Accreditation: CME/CNE
Wednesday, October 14 2:00 PM - 6:00 PM Room: Moscone West, 3rd Floor, Room 3014 - 3018
Session I. MitraClip User’s Guide 2:00 PM - 3:48 PM Moderators: Stephan Baldus, Saibal Kar Discussants: Anita Asgar, Philipp Blanke, Stanley J. Chetcuti, Olaf Franzen, Sameer Gafoor, Ramon Quesada, Corrado Tamburino, Brian K. Whisenant, Steven J. Yakubov
2:00 PM Differences Between the MitraClip and the Alfieri Stitch Frederick G. St. Goar
2:06 PM How and When to Use Multiple MitraClips Saibal Kar
2:12 PM Complications After MitraClip: Frequency, Avoidance, and Treatment Howard C. Herrmann 2:22 PM Recurrent MR After the MitraClip: Frequency, Mechanisms, Predictors, Implications, and Treatment Karl-Heinz Kuck
2:29 PM Mitral Stenosis After the MitraClip Can Occur: Case Example and How to Avoid James B. Hermiller Jr
2:34 PM ASD After MitraClip: Is This the Smoking Gun? Michael J. Lim
2:39 PM Implications of Tricuspid Regurgitation and/or Severe Pulmonary Hypertension in Patients Undergoing MV Surgery or MitraClip Jason H. Rogers
2:46 PM Pushing the Anatomic Envelope of MitraClip Eligibility: What Are the Limits? Michael J. Rinaldi
2:53 PM Pre-debate Vote: Should 2+ MR After MitraClip (or Other Transcatheter Devices) Be Considered a Success? Poll Moderators: Stephan Baldus, Saibal Kar
2:55 PM Debate: Two+ MR After Transcatheter MV Repair as a Failed Procedure – We’ve Learned This From Surgery! Joerg Seeburger
3:01 PM Debate: Open Your Eyes – Two+ MR After Device Related Repair Provides Long-term Benefit! Paul A. Grayburn
3:07 PM Roundtable Discussion With Audience Q&A
3:12 PM Post-debate Vote (Who Won?): Should 2+ MR After MitraClip (or Other Transcatheter Devices) Be Considered a Success? Poll Moderators: Stephan Baldus, Saibal Kar
3:14 PM Techniques to Achieve Less Than or Equal to 1+ MR After MitraClip: How Often Is This Obtainable? Stephan Baldus
3:21 PM MV Surgery After MitraClip: What’s Possible and What’s Not Alfredo Trento
3:27 PM The Tables Turned: MitraClip After Failed Surgical Annuloplasty for Secondary MR Karl-Heinz Kuck
3:33 PM Roundtable Discussion With Audience Q&A
Session II. Transcatheter Mitral Annuloplasty and Ventriculoplasty 3:48 PM - 5:25 PM Moderators: Steven L. Goldberg, Joachim Schofer Discussants: Saif Anwaruddin, Andrejs Erglis, Adam Groothuis, Howard C. Herrmann, Karl-Heinz Kuck, David Meerkin
3:48 PM Carillon: Device Description, Latest Data, and Future Directions Horst Sievert
3:58 PM Carillon: Case in a Box Steven L. Goldberg
4:04 PM Cardioband: Device Description, Latest Data, and Future Directions Karl-Heinz Kuck
4:14 PM Cardioband: Case in a Box Alec S. Vahanian
4:20 PM Cardioband Mechanism of Action: Echocardiographic Insights (2-D and 3-D) Paul A. Grayburn
4:25 PM Mitralign Bident: Device Description, Latest Data, and Future Directions Azeem Latib
4:33 PM Mitralign Bident: Case in a Box Rebecca T. Hahn
4:39 PM Guided Delivery Systems Accucinch: Device Description, Experiences, and Future Directions Franz X. Kleber
4:47 PM MVRx ARTO System (Septal Sinus Shortening) and the MAVERIC Trial Andrejs Erglis
4:55 PM MitraSpan Transapical Segmented Reduction Annuloplasty (TASRA): Rationale and FIM Results Howard C. Herrmann
5:02 PM Multitranscatheter Device Approach to MR: From Theory to Practice Joachim Schofer
5:09 PM Roundtable Discussion With Audience Q&A
Session III. Transcatheter Mitral Valve Therapies: A Debate and a Forward-Looking Prophecy 5:25 PM - 6:00 PM Moderators: Vinod H. Thourani, Brian K. Whisenant Discussants: Danny Dvir, Ted E. Feldman, Jan Kovac, Helge Möllmann, Alec S. Vahanian, Adam Witkowski
5:25 PM Pre-debate Vote: Will Transcatheter MV Replacement Prove to Have Superior Clinical Benefit (More Effective and Similarly Safe) Than MitraClip or Annuloplasty Approaches in Secondary MR? Poll Moderators: Vinod H. Thourani, Brian K. Whisenant 5:27 PM Debate: Yes, Transcatheter MV Replacement Will Become Standard of Care for Secondary MR! Shmuel Banai
5:34 PM Debate: No, the Bar Is Too High – MitraClip/Annuloplasty Approaches Will Always Be Safer and Nearly as Effective! Ted E. Feldman
5:41 PM Roundtable Discussion With Audience Q&A
5:46 PM Post-debate Vote (Who Won?): Will Transcatheter MV Replacement Prove to Have Superior Clinical Benefit (More Effective and Similarly Safe) Than MitraClip or Annuloplasty Approaches in Secondary MR? Poll Moderators: Vinod H. Thourani, Brian K. Whisenant
5:48 PM My Rosy Prophecy: What Will the Specialty of Mitral Valve Therapeutics Look Like in 10 Years? Alec S. Vahanian
5:55 PM Roundtable Discussion With Audience Q&A
Interventional Innovation, Part 3: Late-Breaking Early Feasibility and First-in-Human Clinical Studies Accreditation: none
Wednesday, October 14 8:00 AM - 11:50 AM Room: Moscone West, 2nd Floor, Room 2014 - 2018
Session I. Emerging Cardiovascular Technologies and Interventional Heart Failure 8:00 AM - 10:15 AM Moderators: Andrea Abizaid, Daniel Burkhoff Discussants: Elazer R. Edelman, Tim A. Fischell, Juan F. Granada, Carey D. Kimmelstiel, Ian T. Meredith, Bruno Scheller, Marvin J. Slepian, Glenn Van Langenhove
8:00 AM The Ever-Changing World of Early Human Device Testing: Landscape, Ongoing Global Changes, and Future Opportunities Ian T. Meredith
8:12 AM Efficacy and Safety of Novel NovaCross Microcatheter for Chronic Total Occlusions: First-in-Human Study Leszek Bryniarski
8:20 AM Roundtable Discussion With Audience Q&A
8:25 AM Early First-in-Human Data of Paclitaxel Drug-Coated Chocolate PTCA Coronary Balloon Catheters in De Novo Coronary Lesions J. A. Mustapha
8:33 AM Roundtable Discussion With Audience Q&A 8:38 AM HeartMate Percutaneous Heart Pump (PHP) in High-Risk Coronary Intervention: Results of the SHIELD I Trial Dariusz Dudek
8:46 AM Roundtable Discussion With Audience Q&A
8:51 AM A Randomized Comparison Among Drug Eluting Balloon, Drug Eluting Stents, and Conventional Balloon Angioplasty for Lesions in the Distal Internal Pudendal Artery in Patients with Erectile Dysfunction: The Perfect-3 Study Tzung-Dau Wang
8:59 AM Roundtable Discussion With Audience Q&A
9:04 AM Sirolimus-Eluting Angioplasty Balloon for In-Stent Restenosis (SABRE Trial): Six- Month Clinical and Angiographic Results Juan F. Granada
9:12 AM Roundtable Discussion With Audience Q&A
9:17 AM Shockwave Lithoplasty System for Coronary Applications: Early Imaging Feasibility Human Clinical Study Todd J. Brinton
9:25 AM Roundtable Discussion With Audience Q&A
9:30 AM HeartMate Percutaneous Heart Pump (PHP) in Cardiogenic Shock – Initial Clinical Experience From Prague Jiri Maly
9:38 AM Roundtable Discussion With Audience Q&A
9:43 AM Percutaneous Transluminal Caval Flow Restriction With Counterpulsation Balloon in Ischemic and Nonischemic Heart Failure Patients Jose E. Herrera
9:51 AM Roundtable Discussion With Audience Q&A
9:56 AM Initial Clinical Results of Transcatheter Technique for LV Volume Reduction Treatment of Ischemic Cardiomyopathy Salvatore Brugaletta
10:04 AM Roundtable Discussion With Audience Q&A
Session II. The FDA EFS/Innovation Pathway: Percutaneous Tricuspid and Mitral Valve Intervention Technologies 10:15 AM - 12:05 PM Moderators: Andrew Farb, Jason H. Rogers Discussants: Zahid Amin, Shmuel Banai, Juan F. Granada, Rebecca T. Hahn, Michael J. Mack, David W.M. Muller, Arshad Quadri
10:15 AM Tricuspid Valve Interventions 1: Percutaneous Tricuspid Annuloplasty – The 4Tech TriCinch Device Azeem Latib 10:25 AM Roundtable Discussion With Audience Q&A
10:30 AM Tricuspid Valve Interventions 2: Transcatheter Tricuspid Annular Repair in Patients With Severe Tricuspid Regurgitation – Early First-in-Human Clinical Experience Rebecca T. Hahn
10:40 AM Roundtable Discussion With Audience Q&A
10:45 AM Tricuspid Valve Interventions 3: Edwards FORMA Repair System – Technology Description and First-in-Human Clinical Experience Francisco Campelo-Parada
10:55 AM Roundtable Discussion With Audience Q&A
11:00 AM Arterys: MRI-based Assessment and Quantification of Mitral and Tricuspid Regurgitation Albert Hsiao
11:08 AM The FDA/EFP for New Mitral Valve Replacement Technologies: Lessons Learned, Current Status, and Future Perspectives Changfu Wu
11:18 AM Roundtable Discussion With Audience Q&A
CT Imaging for the Coronary and Structural Interventionalist Accreditation: CME/CNE
Wednesday, October 14 1:00 PM - 2:00 PM Room: Moscone North, Lower Level, Room 125
Session I. CT Imaging for the Coronary Interventionalist 1:00 PM - 1:30 PM Moderators: Hasan Jilaihawi, Christopher K. Zarins Discussants: Stephan Achenbach, Jeroen J. Bax, Jonathon A. Leipsic, James K. Min
1:00 PM Overview of Coronary CT Imaging Stephan Achenbach
1:10 PM Coronary CT Imaging: Ischemia vs Anatomy James K. Min
1:20 PM Roundtable Discussion With Audience Q&A
Session II. CT Imaging for the Structural Interventionalist 1:30 PM - 2:00 PM Moderators: Hasan Jilaihawi, Christopher K. Zarins Discussants: Stephan Achenbach, Jeroen J. Bax, Jonathon A. Leipsic, James K. Min 1:30 PM CT Imaging for Aortic and Mitral Valvular Disease: TAVI, TMVI, and Beyond Jonathon A. Leipsic
1:40 PM CT vs Echo Mitral Valve Imaging Jeroen J. Bax
1:50 PM Roundtable Discussion With Audience Q&A
Fellows Session: PCI Year-in-Review Accreditation: CME
Wednesday, October 14 1:00 PM - 2:00 PM Room: Moscone North, Lower Level, Room 131
Fellows Session: PCI Year-in-Review 1:00 PM - 2:00 PM Moderators: Larry S. Dean, Simon R. Dixon Discussants: Mauro Carlino, Gérard Helft, David E. Kandzari, Julinda Mehilli, Manesh R. Patel
1:00 PM Coronary Intervention Landscape 2015: My Top 5 Observations Julinda Mehilli
1:08 PM Roundtable Discussion With Audience Q&A
1:12 PM ACS/PCI Guidelines and AUC Update: Hitting the Highlights Manesh R. Patel
1:20 PM Roundtable Discussion With Audience Q&A
1:24 PM STEMI PCI: Developments in 2015 Simon R. Dixon
1:32 PM Roundtable Discussion With Audience Q&A
1:36 PM Advanced Stent Designs and Technologies: What Is Coming to the USA? David E. Kandzari
1:44 PM Roundtable Discussion With Audience Q&A
1:48 PM CTO Revascularization: 2015 Update Mauro Carlino
1:56 PM Roundtable Discussion With Audience Q&A International Debating Chamber, Part 1 (Sponsored by BCIS): Structural Heart and Peripheral Vascular Disease Intervention on Trial Accreditation: CME
Wednesday, October 14 1:00 PM - 2:00 PM Room: Moscone North, Lower Level, Room 130
International Debating Chamber, Part 1 (Sponsored by BCIS): Structural Heart and Peripheral Vascular Disease Intervention on Trial 1:00 PM - 2:00 PM Moderators: Adrian P. Banning, Mark A. de Belder Discussants: Anthony H. Gershlick, David Hildick-Smith, Michael J. Mack, Oscar A. Mendiz, Michael J. Mullen
1:00 PM Debate 1: The Requirement for Surgical Involvement in TAVI Planning and Procedures Has Now Passed. I'm For the Proposal! David Hildick-Smith
1:08 PM Debate 1: The Requirement for Surgical Involvement in TAVI Planning and Procedures Has Now Passed. I'm Against the Proposal! Michael J. Mack
1:16 PM Barrister Challenges With Audience Q&A
1:28 PM What Say the Audience Jury (Polling Question)?
1:30 PM Debate 2: Interventional Cardiologists’ On-Call Should Include Primary Intervention for Stroke. I'm for the Proposal! Leo Nelson Hopkins
1:38 PM Debate 2: Interventional Cardiologists’ On-Call Should Include Primary Intervention for Stroke. I'm Against the Proposal! Anthony H. Gershlick
1:46 PM Barrister Challenges With Audience Q&A
1:58 PM What Say the Audience Jury (Polling Question)?
Interventional, Surgical, and Hybrid Coronary Procedures: Case Studies in Conflict and Consensus (Co-sponsored by AATS) Accreditation: CME
Wednesday, October 14 1:00 PM - 2:00 PM Room: Moscone North, Lower Level, Room 132
Interventional, Surgical, and Hybrid Coronary Procedures: Case Studies in Conflict and Consensus (Co-sponsored by AATS) 1:00 PM - 2:00 PM Moderator: John D. Puskas Discussants: Sripal Bangalore, Michael E. Farkouh, Robert J. Gil, Igor F. Palacios, Joseph F. Sabik
1:00 PM Case Introduction: A Complex Diabetic Patient With Heart Failure, Ischemia, and Mitral Regurgitation Case Presenter: John D. Puskas
1:05 PM For This Patient, I Suggest Medical Management and Risk-Factor Reduction Alone (What Have COURAGE and FAME Taught Us?) Michael E. Farkouh
1:13 PM For This Patient, I Suggest Multivessel PCI (the Freedom to Ignore FREEDOM) Sripal Bangalore
1:21 PM For This Patient, I Suggest Addressing the Mitral Valve: MitraClip for IMR After PCI Michael A. Borger
1:29 PM For This Patient, I Suggest Multivessel CABG via Sternotomy, Either On-Pump or Off- Pump (FREEDOM Sets Us Free) Joseph F. Sabik
1:37 PM For This Patient, I Suggest Hybrid Coronary Revascularization (Let’s Split the Difference) John D. Puskas
1:45 PM Roundtable Discussion With Audience Q&A
1:55 PM Case Resolution: How We Treated Our Patient Case Presenter: John D. Puskas
Stroke Management 2015: A Growing Need for Interventionalists Accreditation: CME/CNE
Wednesday, October 14 1:00 PM - 2:00 PM Room: Moscone North, Lower Level, Room 133
Stroke Management 2015: A Growing Need for Interventionalists 1:00 PM - 2:00 PM Moderators: Leo Nelson Hopkins, Horst Sievert Discussants: Klaus C Fassbender, Iris Q. Grunwald, Klaus D. Mathias, Christine Roffe, Gary S. Roubin
1:00 PM Recent Evidence for Thrombectomy, and How It Has Changed My Practice Klaus D. Mathias
1:06 PM Roundtable Discussion With Audience Q&A
1:10 PM The Mobile Stroke Unit (MSU): A Mechanism to Triage Patients With Acute Stroke Klaus C Fassbender
1:16 PM Roundtable Discussion With Audience Q&A
1:20 PM Use of The e-ASPECTS Software on Noncontrast CT Scans for Automated Detection of Acute Ischemic Stroke Christine Roffe
1:26 PM Roundtable Discussion With Audience Q&A
1:30 PM Training for Stroke Intervention 1: My Experience at CVC Frankfurt Horst Sievert
1:36 PM Roundtable Discussion With Audience Q&A
1:40 PM Training for Stroke Intervention 2: Use of High-Fidelity Simulators – The Southend Experience and Treatment Pathway Iris Q. Grunwald
1:46 PM Roundtable Discussion With Audience Q&A
1:50 PM How to Manage the Growing Demand for Stroke Interventionists? Leo Nelson Hopkins
1:56 PM Roundtable Discussion With Audience Q&A
Bioresorbable Vascular Scaffolds Accreditation: CME/CNE
Wednesday, October 14 1:00 PM - 2:00 PM Room: Moscone North, Lower Level, Room 122
Bioresorbable Vascular Scaffolds 1:00 PM - 2:00 PM Moderators: Antonio Colombo, Nicolas M. Van Mieghem Discussants: Philippe L. L'Allier, Azeem Latib, Teguh Santoso, Ashok Seth
1:00 PM Introduction: The Ideal BRS Candidate – Patient Selection When Starting Up a BRS Program Antonio Colombo
1:06 PM Roundtable Discussion With Audience Q&A
1:10 PM Must-have Tools for BRS: Procedural Planning Ashok Seth
1:16 PM Roundtable Discussion With Audience Q&A
1:20 PM Optimal BRS Implantation Assessment: Angiography vs Intravascular Imaging (Case Examples) Philippe L. L'Allier
1:26 PM Roundtable Discussion With Audience Q&A
1:30 PM Complex Lesion Preparation for BRS (Calcification and Bifurcations) (Case Examples) Teguh Santoso
1:36 PM Roundtable Discussion With Audience Q&A
1:40 PM Tips and Tricks to Solve BRS-Related Problems (Case Examples) Azeem Latib
1:46 PM Roundtable Discussion With Audience Q&A
1:50 PM Lesions to Avoid With BRS – For Now! (Case Examples) Nicolas M. Van Mieghem
1:56 PM Closing Remarks Antonio Colombo
CTO Antegrade Reentry Techniques Accreditation: CME/CNE
Wednesday, October 14 1:00 PM - 2:00 PM Room: Moscone North, Lower Level, Room 120
CTO Antegrade Reentry Techniques 1:00 PM - 2:00 PM Moderators: J. Aaron Grantham, Ashish Pershad Discussants: David Daniels, Stéphane Rinfret, R. Michael Wyman, Yuejin Yang
1:00 PM Evolution of ADR Techniques: From STAR to Stingray J. Aaron Grantham
1:10 PM Roundtable Discussion With Audience Q&A
1:16 PM Antegrade IVUS-Guided True Lumen Seeking and Tracking Technique Yuejin Yang
1:24 PM Controlled ADR: The BridgePoint Device Step-by-Step for Beginners Case Presenter: David Daniels
1:32 PM High-end ADR: Becoming a Master of Controlled ADR R. Michael Wyman
1:40 PM Roundtable Discussion With Audience Q&A 1:45 PM Safety and Durability of Subintimal Stenting Stéphane Rinfret
1:55 PM Roundtable Discussion With Audience Q&A
Management of Calcified Coronary Lesions Accreditation: CME/CNE
Wednesday, October 14 1:00 PM - 2:00 PM Room: Moscone North, Lower Level, Room 124
Management of Calcified Coronary Lesions 1:00 PM - 2:00 PM Moderator: Jeffrey W. Moses Discussants: Mohamed Abdel-Wahab, Maurice Buchbinder, John McB. Hodgson, Manish A. Parikh, Adam J. de Belder
1:00 PM Updated Evidence for Treatment of Calcified Lesions: What Are the Options? Philippe Généreux
1:05 PM Role of Imaging in Calcified Lesion Preparation and Treatment: Case Examples Case Presenter: Manish A. Parikh
1:15 PM Is There a Place for “Balloon-Only” Preparation of Calcified Lesions? Case Examples Case Presenter: Mohamed Abdel-Wahab
1:25 PM Roundtable Discussion With Audience Q&A
1:30 PM My Best and Worst Cases of Rotational Atherectomy: What I’ve Learned Over the Years Case Presenter: Maurice Buchbinder
1:40 PM My Best and Worst Cases of Orbital Atherectomy: Learning to Use a New Tool Case Presenter: Jeffrey W. Moses
1:50 PM Roundtable Discussion With Audience Q&A
TAVR Tips and Tricks Accreditation: CME/CNE
Wednesday, October 14 1:00 PM - 2:00 PM Room: Moscone North, Lower Level, Room 121 Session I. TAVR Tips and Tricks 1:00 PM - 2:00 PM Moderators: Susheel Kodali, Jean-Claude Laborde Discussants: Raj Makkar, Molly Szerlip, Vinod H. Thourani, Mathew Williams
1:00 PM Which Valve, Which Size, and Why, Part 1? Balloon Expandable Susheel Kodali
1:07 PM Roundtable Discussion With Audience Q&A
1:10 PM Which Valve, Which Size, and Why, Part 2? Self Expanding Jean-Claude Laborde
1:17 PM Roundtable Discussion With Audience Q&A
1:20 PM TAVR in a Horizontal Aorta: Tips and Tricks (With a Case) Raj Makkar
1:27 PM Roundtable Discussion With Audience Q&A
1:30 PM TAVR for Bicuspid Valves (With a Case): Should You Do It, and if so, How? Molly Szerlip
1:37 PM Roundtable Discussion With Audience Q&A
1:40 PM The Sapien 3 THV: Understanding the New Sizing Algorithm and Deployment Characteristics (With a Case) Vinod H. Thourani
1:47 PM Roundtable Discussion With Audience Q&A
1:50 PM The Evolut R THV: Tips and Tricks for Using the InLine Sheath (With a Case) Mathew Williams
1:57 PM Roundtable Discussion With Audience Q&A
Transradial Intervention Accreditation: CME/CNE
Wednesday, October 14 1:00 PM - 2:00 PM Room: Moscone North, Lower Level, Room 123
Transradial Intervention 1:00 PM - 2:00 PM Moderator: Samir B. Pancholy Discussants: Mauricio G. Cohen, Ian C. Gilchrist, Ferdinand Kiemeneij, Tejas Patel
1:00 PM Radial Puncture, Navigation, and Guide Catheter Challenges: A Case-Based Review Case Presenter: Tejas Patel
1:12 PM Roundtable Discussion With Audience Q&A
1:15 PM Complex PCI via Radial Access: Case-Based Problem Solving Case Presenter: Ferdinand Kiemeneij
1:27 PM Roundtable Discussion With Audience Q&A
1:30 PM Transradial Access for Primary PCI and Shock Mauricio G. Cohen
1:42 PM Roundtable Discussion With Audience Q&A
1:45 PM Management of Radial Complications: Case Examples Case Presenter: Samir B. Pancholy
1:57 PM Roundtable Discussion With Audience Q&A
FDA Town Hall, Part 2, Wednesday, Oct. 14 Accreditation: CME/CNE
Wednesday, October 14 2:00 PM - 6:00 PM Room: Moscone West, 2nd Floor, Room 2007 - 2011
Session V. Topic-Oriented Controversies, Part 1: Interventional Pharmacology 2:00 PM - 2:51 PM Moderators: Deepak L. Bhatt, Martin Rose Discussants: Angeles Alonso Garcia, Steven R. Bailey, John A. Bittl, Andrew Farb, C. Michael Gibson, Robert A. Harrington, Roxana Mehran, Gregg W. Stone, Freek W.A. Verheugt
2:00 PM Identifying and Studying Data Gaps: Cangrelor Use – What's Settled, and What's Not? Gregg W. Stone
2:07 PM Identifying and Studying Data Gaps: DAPT Duration – What's Settled, and What's Not? John A. Bittl
2:14 PM Identifying and Studying Data Gaps: "Triple Therapy" – What's Settled, and What's Not? C. Michael Gibson
2:21 PM Roundtable Discussion With Audience Q&A
Session VI. Topic-Oriented Controversies, Part 2: TAVR 2:51 PM - 3:42 PM Moderators: Nicole Ibrahim, Martin B. Leon Discussants: Michael A. Borger, John C Laschinger, Azin Parhizgar, Nicolo Piazza, Jeffrey J. Popma, Jaime Raben, Rhonda J Robb, Larry L. Wood
2:51 PM Valve Thrombosis/Leaflet Thickening: To Treat or Not to Treat Raj Makkar
2:58 PM Controversial Viewpoint: Possible Trial Designs to Support Approval of TAVR in "Lower-Risk" Patients – Academic Perspectives Nicolo Piazza
3:05 PM Controversial Viewpoint: Possible Trial Designs to Support Approval of TAVR in "Lower-Risk" Patients – Industry Perspectives Larry L. Wood
3:12 PM Roundtable Discussion With Audience Q&A
Session VII. Topic-Oriented Controversies, Part 3: Mitral Valve Repair/Replacement 3:42 PM - 4:26 PM Moderators: John C Laschinger, Michael J. Mack Discussants: William T. Abraham, Ted E. Feldman, Linda D. Gillam, Saibal Kar, Neil E. Moat, Jason H. Rogers, Chuck Simonton, Julie A. Swain, Changfu Wu
3:42 PM Controversial Viewpoints: Clinical Trial Designs for Transcatheter Repair/Replacement of Functional MR – POINT: Defending MVARC and COAPT as the “Clear” Path to Approval Michael J. Mack
3:49 PM Controversial Viewpoints: Clinical Trial Designs for Transcatheter Repair/Replacement of Functional MR – COUNTERPOINT: The COAPT Bar Is Set Too High and Alternative Trial Designs Are Needed! Neil E. Moat
3:56 PM Roundtable Discussion With Audience Q&A
Session VIII. Topic-Oriented Controversies, Part 4: Left Atrial Appendage Closure 4:26 PM - 5:02 PM Moderators: Nicole Ibrahim, Saibal Kar Discussants: Ori Ben-Yehuda, Maurice Buchbinder, Andrew Farb, Samir R. Kapadia, James Rollins, Craig A. Thompson, Zoltan G. Turi, Ron Waksman, Brian K. Whisenant
4:26 PM Data Gaps and Future Trial Pathways: Possible Study Designs for New Devices, Anticoagulation Ineligible Patients, and Comparative NOAC Data Zoltan G. Turi
4:26 PM Roundtable Discussion With Audience Q&A
Session IX. Topic-Oriented Controversies, Part 5: Bioresorbable Scaffolds 5:02 PM - 6:00 PM Moderators: Andrew Farb, Gregg W. Stone Discussants: Alexandre Abizaid, Ori Ben-Yehuda, Kenya Brothers, Robert A. Byrne, Stephen G. Ellis, Juan F. Granada, Michael C. John, Richard J. Rapoza, John A. Spertus, Ron Waksman
5:02 PM Controversial Viewpoint: Characterizing BRS “Class Effects” – BRS Designs Are More Different Than Alike (Regulatory Implications) Juan F. Granada
5:09 PM Key Elements of BRS Nonclinical Testing to Support IDE Approval Michael C. John
5:16 PM Incorporating Quality-of-Life and Patient-Oriented Outcomes in the Device Regulatory Approval Process John A. Spertus
5:23 PM Possible Clinical Trial Designs to Demonstrate the Relative Benefits of BRS vs Permanent Platform DES Chuck Simonton
5:30 PM Roundtable Discussion With Audience Q&A
Complex Angioplasty and Acute Coronary Syndrome: Regional Differences in Primary PCI and Case Complications Presented by the Portuguese Association of Interventional Cardiology (APIC), Sociedade Brasileira de Hemodinâmica e Cardiología Intervencionista (SBHCI), Colegio Argentino de Cardioangiólogos Intervencionistas (CACI), Hong Kong Stent, Philippine Heart Association, and the Singapore Cardiac Society Accreditation: none
Wednesday, October 14 8:30 AM - 10:32 AM Room: Moscone North, Lower Level, Presentation Theater 1
Complex Angioplasty and Acute Coronary Syndrome: Regional Differences in Primary PCI and Case Complications 8:30 AM - 10:32 AM Moderator: Oscar A. Mendiz Discussants: Jose Nicolas M. Cruz, Michael Kang-Yin Lee, Helder Horta Pereira, TBA
8:30 AM Portugal Presents: Differences and Similarities Between NSTEMI and STEMI PCI – Contemporary Insight From the Portuguese National Registry Through 2 Cases Case Presenter: Eduardo Infante de Oliveira
8:40 AM Roundtable Discussion With Audience Q&A
8:45 AM Brazil Presents: Left Main and Double Bifurcation Angioplasty With Guidewire Fracture Case Presenter: TBA
8:55 AM Roundtable Discussion With Audience Q&A 9:00 AM Argentina Presents: Primary PCI or Lytics – Does 1 Size Fit All in LATAM? Case Presenter: Oscar A. Mendiz
9:10 AM Roundtable Discussion With Audience Q&A
9:15 AM Hong Kong Presents: A Fatal Complication During Emergency PCI Case Presenter: Jaclyn Chan
9:25 AM Roundtable Discussion With Audience Q&A
9:30 AM Philippines Presents: Primary PCI in a Comatose Out-of-Hospital Cardiac Arrest Survivor Case Presenter: Jose Nicolas M. Cruz
9:40 AM Roundtable Discussion With Audience Q&A
9:45 AM Singapore Presents: Current Method of Primary PCI in Asia Pacific Case Presenter: Khung Keong Yeo
9:55 AM Roundtable Discussion With Audience Q&A
10:00 AM Stent for Life in Europe Presents: "Stent for Life” Initiative: The Portuguese Experience Case Presenter: Helder Horta Pereira
10:10 AM Roundtable Discussion With Audience Q&A
10:15 AM Stent for Life in Argentina Presents: The Stent for Life Initiative – Current Situation of AMI Treatment in Argentina Case Presenter: Anibal A. Damonte
10:25 AM Roundtable Discussion With Audience Q&A
10:30 AM Closing Remarks Oscar A. Mendiz
Complex Percutaneous Interventions in Acute Myocardial Infarction Presented by the Hungarian Association of Cardiovascular Intervention; Spanish Working Group on Interventional Cardiology; Sociedad de Cardiologia Intervencionista de Mexico (SOCIME); Polish Association of Cardiovascular Interventions; Working Group of Interventional Cardiology, Romanian Society of Cardiology; and Bulgarian Society of Cardiology Accreditation: none
Wednesday, October 14 8:30 AM - 10:30 AM Room: Moscone North, Lower Level, Presentation Theater 2
Complex Percutaneous Interventions in Acute Myocardial Infarction 8:30 AM - 10:30 AM Moderators: Marco A. Alcocer-Gamba, Stefan Mot, Ivo Petrov, Ramiro Trillo Discussants: Dariusz Dudek, Istvan F. Edes, Jacek Legutko, Zoltan Ruzsa, Adam Witkowski, Lucian Zarma 8:30 AM Hungary Presents: Recurrent NSTEMI in a Heart Transplant Recipient Case Presenter: Istvan F. Edes
8:35 AM How Should This Patient Be Treated? Roundtable Discussion With Audience Q&A
8:45 AM How Did I Treat This Patient? Case Presenter: Istvan F. Edes
8:52 AM Roundtable Discussion With Audience Q&A
9:00 AM Spain Presents: Acute Stent Thrombosis Immediately After Primary Angioplasty Case Presenter: Ramiro Trillo
9:05 AM How Should This Patient Be Treated? Roundtable Discussion With Audience Q&A
9:15 AM How Did I Treat This Patient? Case Presenter: Ramiro Trillo
9:22 AM Roundtable Discussion With Audience Q&A
9:30 AM Mexico Presents: In-Stent Restenosis Treated With Atherectomy and Implantation of 3 Stents Case Presenter: JOSE R Azpiri-Lopez
9:35 AM How Should This Patient Be Treated? Roundtable Discussion With Audience Q&A
9:45 AM How Did I Treat This Patient? Case Presenter: JOSE R Azpiri-Lopez
9:52 AM Roundtable Discussion With Audience Q&A
10:00 AM Poland Presents: A Patient With NSTEMI and Severe Aortic Stenosis Case Presenter: Andrzej J. Ochala
10:05 AM How Should This Patient Be Treated? Roundtable Discussion With Audience Q&A
10:15 AM How Did I Treat This Patient? Case Presenter: Andrzej J. Ochala
10:22 AM Roundtable Discussion With Audience Q&A
Featured Clinical Research III: Presentations to the Editors of the European Heart Journal Accreditation: CME
Wednesday, October 14 12:15 PM - 1:45 PM Room: Moscone South, Lower Level, Room 104
Presentations to the Editors of the European Heart Journal 12:15 PM - 1:45 PM Moderators: Bernard J. Gersh, Thomas F. Luscher Discussants: Bernard De Bruyne, Roxana Mehran, Lorenz Raber, Patrick W. Serruys, Alec S. Vahanian
12:15 PM Evaluation of Percutaneous Closure of Paravalvular Leak After Failed Surgical Valve Replacement: The UK and Irish Experience Patrick A. Calvert
12:25 PM Roundtable Discussion With Audience Q&A
12:30 PM MISTRAL C: A Prospective Randomized Trial of Embolic Protection During Transcatheter Aortic Valve Replacement Nicolas M. Van Mieghem
12:40 PM Roundtable Discussion With Audience Q&A
12:45 PM PRESTIGE: Optical Coherence Tomography Findings in Patients Presenting With Stent Thrombosis Giulio Guagliumi
12:55 PM Roundtable Discussion With Audience Q&A
1:00 PM TWENTE: A Prospective Randomized Trial of a Durable-Polymer Zotarolimus-Eluting Stent Versus a Durable-Polymer Everolimus-Eluting Stent in Patients With Coronary Artery Disease – Five-Year Outcomes Clemens von Birgelen
1:10 PM Roundtable Discussion With Audience Q&A
1:15 PM MEMENTO FFR: Evaluation of Contrast-Induced Submaximal Hyperemia in Patients With Coronary Artery Lesions of Intermediate Severity Antonio Maria Leone
1:25 PM Roundtable Discussion With Audience Q&A
1:30 PM MASTER: A Prospective Randomized Trial of a Bioabsorbable-Polymer Biolimus- Eluting Stent Versus Bare-Metal Stents in Patients With ST-Segment Elevation Myocardial Infarction Cesar Moris
1:40 PM Roundtable Discussion With Audience Q&A
The BioNIR eDES Study: The Role of Uniformity in Stent Design to Minimize Restenosis (Sponsored by Medinol U.S.A., Inc.) Accreditation: none
Wednesday, October 14 6:30 AM - 8:00 AM Room: Moscone North, Lower Level, Room 125
Check-in and Breakfast 6:30 AM - 7:00 AM
The BioNIR eDES Study: The Role of Uniformity in Stent Design to Minimize Restenosis 7:00 AM - 8:00 AM Chairs: David E. Kandzari, Yoram Richter, PhD Facultys: Shmuel Banai, Rajiv Jauhar, MD, Pieter C. Smits, James P. Zidar
7:00 AM Welcome and Introductions Yoram Richter, PhD
7:02 AM Do We Need Bare Metal Stents Anymore? James P. Zidar
7:10 AM Unique Handling Characteristics of a Novel Delivery System Rajiv Jauhar, MD
7:20 AM BioNIR eDES: A Different Approach to Stent Design and Manufacturing Yoram Richter, PhD
7:32 AM Changing Clinical Study Methodology: Overview of BIONICS and NIREUS David E. Kandzari
7:44 AM Panel Discussion on Deliverability With a New Delivery System Moderator: David E. Kandzari
7:55 AM Audience Q&A Moderator: David E. Kandzari
Contrast-Induced Acute Kidney Injury: Focus on Hydration and Dye Saving (Sponsored by Cardiovascular Research Foundation) (Supported by Osprey Medical and RenalGuard Solutions, Inc.) Accreditation: none
Wednesday, October 14 6:30 AM - 8:00 AM Room: Moscone North, Lower Level, Room 130
Check-in and Breakfast 6:30 AM - 7:00 AM
Contrast-Induced Acute Kidney Injury: Focus on Hydration and Dye Saving 7:00 AM - 8:00 AM Chair: Roxana Mehran Facultys: Antonio L. Bartorelli, Somjot S. Brar, Carlo Briguori, Steffen Desch, Hitinder S. Gurm
7:00 AM Welcome and Introductions Faculty: Roxana Mehran 7:05 AM Importance of Hydration: How to Do It Best? RenalGuard Therapy Carlo Briguori
7:15 AM Dye Saving Tips: The AVERT System Steffen Desch
7:25 AM Case Presentation: A Difficult Patient at High Risk for AKI - How to Choose Optimal Dye Savings and Hydration Methods Antonio L. Bartorelli
7:50 AM Discussion: The Future of AKI Regarding Contrast and Hydration Status Discussants: Somjot S. Brar, Hitinder S. Gurm
Integrating Physiology and Imaging Into the Cath Lab: What Technology Should I Use, and How and When Should I Use It? (Sponsored by Cardiovascular Research Foundation) (Supported By Boston Scientific Corporation, Infraredx, Inc., Medtronic, Inc., and St. Jude Medical, Inc.) Accreditation: none
Wednesday, October 14 6:30 AM - 8:00 AM Room: Moscone North, Lower Level, Room 122
Check-in and Breakfast 6:30 AM - 7:00 AM
Integrating Physiology and Imaging Into the Cath Lab: What Technology Should I Use, and How and When Should I Use It? 7:00 AM - 8:00 AM Chairs: John McB. Hodgson, Gary S. Mintz Facultys: Emmanouil S. Brilakis, Shao-Liang Chen, Allen Jeremias
7:00 AM How Do I Assess an Intermediate Lesion? Allen Jeremias
7:10 AM How Do I Predict (and Hopefully Avoid) Distal Embolization When Implanting a Stent? Emmanouil S. Brilakis
7:20 AM How Do I Optimize Stent Implantation? John McB. Hodgson
7:30 AM How and When Do I Assess a Jailed Side Branch After Provisional Stenting? Shao-Liang Chen
7:40 AM How Do I Assess Causes of Stent Thrombosis and In-Stent Restenosis? Gary S. Mintz 7:50 AM Discussion
Management of Complex PCI Patients: Award-Winning Case Presentations (Sponsored by the Cardiovascular Research Foundation) (Supported through a grant from ABIOMED, Inc.) Accreditation: none
Wednesday, October 14 6:30 AM - 8:00 AM Room: Moscone North, Lower Level, Room 121
Check-In and Breakfast 6:30 AM - 7:00 AM
Management of Complex PCI Patients 7:00 AM - 8:00 AM Chairs: Jose P.S. Henriques, Theodore L. Schreiber, George W. Vetrovec Facultys: Ehtisham Mahmud, Perwaiz M. Meraj, Roberto Nerla, Dagmar M. Ouweneel, Jeremy D Rier
7:00 AM Bail-out Use of Impella CP as a Bridge to TAVI in a Cardiogenic Shock Patient: The ‘Pump-Rewiring’ Technique Case Presenter: Roberto Nerla
7:15 AM Q&A
7:20 AM Impella Placement Before Primary PCI of a Left Main Occlusion Case Presenter: Dagmar M. Ouweneel
7:35 AM Q&A
7:40 AM High Risk PCI – Sometimes It’s Necessary to PROTECT Case Presenter: Jeremy D Rier
7:55 AM Q&A
Novel Devices for Transcatheter Valve Implantation: ACURATE neo™ Highlights (Sponsored by SYMETIS SA) Accreditation: none
Wednesday, October 14 6:30 AM - 8:00 AM Room: Moscone North, Lower Level, Room 124
Check-in and Breakfast 6:30 AM - 7:00 AM Novel Devices for Transcatheter Valve Implantation: ACURATE neo™ Highlights 7:00 AM - 8:00 AM Chair: Alexandre Abizaid Facultys: Pantelis Diamantouros, Helge Möllmann, Ulrich Schäfer, MD
7:00 AM Welcome Chair: Alexandre Abizaid
7:05 AM ACURATE neo TAVI: Rationale and Supporting Data Helge Möllmann
7:15 AM Single Canadian Center Experience Under Special Access Pantelis Diamantouros, MD
7:25 AM Case Selection Insights Ulrich Schäfer, MD
7:35 AM Discussion and Summary
PCI Complications: The Best of the Worst (Sponsored by the Cardiovascular Research Foundation) (Supported by Medtronic, Inc.) Accreditation: none
Wednesday, October 14 6:30 AM - 8:00 AM Room: Moscone North, Lower Level, Room 123
Check-in and Breakfast 6:30 AM - 7:00 AM
PCI Complications: The Best of the Worst 7:00 AM - 8:00 AM Chairs: Antonio Colombo, Manish A. Parikh Facultys: Nirat Beohar, David A. Cox, J. Aaron Grantham, Daniel I. Simon
7:00 AM The Coronary Perforation Nightmare J. Aaron Grantham
7:10 AM Discussion
7:15 AM The Coronary That “Spiraled Out of Control” Daniel I. Simon
7:25 AM Discussion
7:30 AM The "Slam Dunk" STEMI: No Reflow and Beyond David A. Cox 7:40 AM Discussion
7:45 AM My Worst Vascular Complication of the Year Nirat Beohar
7:55 AM Discussion
Renal Denervation Therapies: Current Evidence and Controversies (Sponsored by the Cardiovascular Research Foundation) (Supported by Boston Scientific Corporation, Medtronic, Inc., ReCor Medical, and St. Jude Medical) Accreditation: none
Wednesday, October 14 6:30 AM - 8:00 AM Room: Moscone North, Lower Level, Room 120
Check-in and Breakfast 6:30 AM - 8:00 AM
Renal Denervation Therapies: Current Evidence and Controversies 7:00 AM - 8:00 AM Chairs: Ajay J. Kirtane, Martin B. Leon Facultys: Juan F. Granada, David E. Kandzari, Felix Mahfoud, Krishna J. Rocha-Singh
7:00 AM Welcome and Introductions Chair: Martin B. Leon
7:02 AM Rapid Data Download: Current State of the Evidence for RDN in Hypertension David E. Kandzari
7:12 AM Audience Q&A
7:15 AM Preclincial Insights and Advances in the Understanding of Renal Denervation Therapies Juan F. Granada
7:28 AM Audience Q&A
7:32 AM How I Use (and Study) Renal Denervation in My Center: Everything You Need to Know, With Case Examples Felix Mahfoud
7:45 AM Audience Q&A
7:50 AM Predicting the Path Ahead for Renal Denervation Therapies Krishna J. Rocha-Singh Complex PCI Case-Based Review: SCAI Women in Innovations (WIN) (Sponsored by Abbott and ABIOMED, Inc.) Accreditation: none
Wednesday, October 14 11:30 AM - 12:30 PM Room: Moscone North, Lower Level, Hall D, Presentation Theater 1
Complex PCI Case-Based Review: SCAI Women in Innovations (WIN) 11:30 AM - 12:30 PM Facultys: Anu Abraham, MD, Jaya Chandrasekhar, Cindy L. Grines, Wah Wah Htun, MD, Amir Kaki, MD, Roxana Mehran, Kimberly A. Skelding, Paul S. Teirstein
11:30 AM Case Review #1 - Complex PCI Moderator: Cindy L. Grines Case Presenter: Anu Abraham, MD Discussants: Amir Kaki, MD, Roxana Mehran, Ruby Satpathy, MD, Kimberly A. Skelding, Paul S. Teirstein
11:50 AM Case Review #2 – Complex PCI (Impella) Moderator: Cindy L. Grines Case Presenter: Wah Wah Htun, MD Discussants: Amir Kaki, MD, Roxana Mehran, Ruby Satpathy, MD, Kimberly Skelding, MD, Paul S. Teirstein
12:10 PM Case Review #3 – Complex PCI Moderator: Cindy L. Grines Case Presenter: Jaya Chandrasekhar Discussants: Amir Kaki, MD, Roxana Mehran, Ruby Satpathy, MD, Kimberly A. Skelding, Paul S. Teirstein
Noninvasive FFRct: Optimizing Outcomes With Physiology-Guided Coronary Revascularization (Sponsored by HeartFlow) Accreditation: none
Wednesday, October 14 11:30 AM - 12:30 PM Room: Moscone South, Lower Level, Exhibit Hall, Presentation Theater 4
Noninvasive FFRct: Optimizing Outcomes With Physiology-Guided Coronary Revascularization 11:30 AM - 12:30 PM Chair: Bernard De Bruyne Facultys: Pamela S. Douglas, Morton J. Kern, Daniel I. Simon
11:30 AM Introduction to Noninvasive FFRct Chair: Bernard De Bruyne
11:35 AM Physiological Lesion Assessment: FFRct: What Is It, and Why Is It Important? Morton J. Kern 11:50 AM FFRct: Clinical Trial Update Pamela S. Douglas
12:05 PM Case Review: Incorporating FFRct Into Clinical Practice Case Presenter: Daniel I. Simon
12:20 PM Discussion and Summary
Real-World Experience From Complex Cases With the Lotus™ Valve (Sponsored by Boston Scientific Corporation) Accreditation: none
Wednesday, October 14 11:30 AM - 12:30 PM Room: Moscone South, Lower Level, Exhibit Hall, Presentation Theater 3
Real-World Experience From Complex Cases With the Lotus™ Valve 11:30 AM - 12:30 PM Chairs: Ted E. Feldman, Ian T. Meredith Facultys: Vinayak Bapat, Giuseppe D'Ancona, MD, Matthias Götberg, MD
11:30 AM Session Objectives, Lotus™ System Overview, and Clinical Program Overview Ted E. Feldman
11:35 AM My Real-World Experience With the Lotus™ Valve Matthias Götberg, MD
11:45 AM How a Second-Generation Valve Improves Clinical Outcomes: The Berlin Experience Giuseppe D'Ancona, MD
11:55 AM Discussion Moderators: Ted E. Feldman, Ian T. Meredith
12:00 PM The Lotus™ Valve: A Cardiac Surgeon’s Perspective Vinayak Bapat
12:10 PM Discussion Moderators: Ted E. Feldman, Ian T. Meredith
12:20 PM NG Lotus Edge: Early Clinical Experience and Pipeline Ian T. Meredith
What Every Interventionalist Needs to Know About Atrial Fibrillation and Anticoagulation and the Role of Antidotes (Sponsored by Boehringer Ingelheim Pharmaceuticals, Inc., Boston Scientific Corporation, Bristol-Myers Squibb and Pfizer, Inc., Daiichi Sankyo, Inc., and Janssen Pharmaceuticals) Accreditation: none
Wednesday, October 14 11:30 AM - 12:30 PM Room: Moscone North, Lower Level, Hall D, Presentation Theater 2
What Every Interventionalist Needs to Know About Atrial Fibrillation, Anticoagulation, and the Role of Antidotes 11:30 AM - 12:30 PM Co-Chair: Michael D. Ezekowitz Facultys: C. Michael Gibson, William A. Gray, Roxana Mehran
11:30 AM Pharmacology of Novel Anticoagulants and Their Antidotes Michael D. Ezekowitz
11:45 AM Anticoagulation, Atrial Fibrillation, and Antidotes in the Setting of ACS C. Michael Gibson
11:55 AM Anticoagulation and Atrial Fibrillation in the Setting of TAVR Roxana Mehran
12:05 PM Anticoagulation and Atrial Fibrillation in the Setting of LAA Closure William A. Gray
12:15 PM Discussion: Illustrative Cases
Bleeding Risk and 1-Month DAPT: Can LEADERS FREE Shift the Paradigm? (Sponsored by Biosensors International Group Ltd.) Accreditation: none
Wednesday, October 14 1:00 PM - 2:00 PM Room: Moscone South, Lower Level, Exhibit Hall, Presentation Theater 4
Bleeding Risk and 1-Month DAPT: Can LEADERS FREE Shift the Paradigm? 1:00 PM - 2:00 PM Chairs: Marie-Claude Morice, Robaayah Zambahari Facultys: Alexandre Abizaid, Spencer B. King III, Philip M. Urban
1:00 PM Welcome and Introduction Chair: Robaayah Zambahari
1:05 PM High–Bleeding-Risk Patients: What Do We Actually Know? Spencer B. King III
1:20 PM The BioFreedom DCS for Patients at High Bleeding Risk: LEADERS FREE Revisited Alexandre Abizaid
1:35 PM How Does the LEADERS FREE RCT Impact Current PCI and DAPT Strategies? Philip M. Urban
1:50 PM Conclusion and Take-home Message Chair: Marie-Claude Morice
IN.PACT SFA Trial 2-Year Outcomes: Will this Evidence Shift the PAD Treatment Paradigm? (Sponsored by Medtronic PLC) Accreditation: none
Wednesday, October 14 1:00 PM - 2:00 PM Room: Moscone North, Lower Level, Hall D, Presentation Theater 2
IN.PACT SFA Trial 2-Year Outcomes: Will this Evidence Shift the PAD Treatment Paradigm? 1:00 PM - 2:00 PM Facultys: John R. Laird Jr, Gunnar Tepe, Renu Virmani
1:00 PM Deep Dive: IN.PACT SFA 2-Year Outcomes John R. Laird Jr
1:15 PM Understanding the Science Behind the Latest Evidence Renu Virmani
1:30 PM Is this Evidence Practice Changing? Gunnar Tepe
1:45 PM Discussion
Metallic and Bioresorbable: Examining the Potential of Two PCI Therapies (Sponsored by Abbott) Accreditation: none
Wednesday, October 14 1:00 PM - 2:00 PM Room: Moscone North, Lower Level, Hall D, Presentation Theater 1
Metallic and Bioresorbable: Examining the Potential of Two PCI Therapies 1:00 PM - 2:00 PM Facultys: James B. Hermiller Jr, Ron Waksman, Nick E. J. West
1:00 PM Introduction Chair: Ron Waksman
1:05 PM Exploring Metallic Stent Options and Benefits James B. Hermiller Jr
1:25 PM Exploring the Benefits of Bioresorbable Vascular Scaffolds Nick E. J. West
1:45 PM Roundtable Discussion With Audience Q&A Moderator: Ron Waksman
Transforming PCI With the DESolve Novolimus-Eluting Scaffold Platforms (Sponsored by Elixir Medical Corporation) Accreditation: none
Wednesday, October 14 1:00 PM - 2:00 PM Room: Moscone South, Lower Level, Exhibit Hall, Presentation Theater 3
Transforming PCI With the DESolve Novolimus-Eluting Scaffold Platforms 1:00 PM - 2:00 PM Chairs: Alexandre Abizaid, Martin B. Leon Facultys: Ian T. Meredith, Hoger Nef, MD, John A. Ormiston
1:00 PM Introduction and Objectives Chair: Alexandre Abizaid
1:05 PM DESolve Scaffold Differentiating Characteristics John A. Ormiston
1:15 PM DESolve NX Trial 3-Year Clinical and Imaging Results Martin B. Leon
1:25 PM DESolve Platform(s) Real-World Experience Hoger Nef, MD
1:35 PM DESolve Future Clinical Studies Ian T. Meredith
1:45 PM Discussion and Audience Interaction
1:55 PM Take-home Message Chair: Martin B. Leon ACS/STEMI: Focus on Acute and Chronic Care (Sponsored by the Cardiovascular Research Foundation) (Supported by Daiichi Sankyo, Inc. and Lilly USA, LLC, Medtronic, Inc., and The Medicines Company) Accreditation: none
Wednesday, October 14 6:00 PM - 8:00 PM Room: Hilton Union Square, Ballroom Level, Continental Ballroom 5-6
Check-in and Reception 6:00 PM - 6:30 PM
Welcome, Introductions and Course Objectives 6:29 PM - 6:30 PM Chair: Roxana Mehran
Treatment of STEMI 6:30 PM - 7:15 PM Chairs: Ajay J. Kirtane, Roxana Mehran Facultys: Keith A. Fox, MD, C. Michael Gibson, Duane S. Pinto, Matthew J. Price, Gregg W. Stone
6:30 PM Clopidogrel, Ticagrelor, or Prasugrel in STEMI: How Do You Choose? Case Presenter: Matthew J. Price
6:38 PM IV Agents: Cangrelor or GP IIb/IIIa Inhibitors in STEMI? Case Presenter: C. Michael Gibson
6:46 PM Discharging a Patient Home: How to Choose Which Agent, and for How Long? Case Presenter: Keith A. Fox, MD
6:55 PM STEMI Case Presentation Case Presenter: Roxana Mehran
7:05 PM STEMI Roundtable Discussion: What Is Next, and How Can We Do Better? Moderator: Roxana Mehran
Non-ST-Segment Elevation - Acute Coronary Syndromes 7:15 PM - 8:00 PM Chairs: Ajay J. Kirtane, Roxana Mehran Facultys: Keith A. Fox, MD, C. Michael Gibson, Duane S. Pinto, Matthew J. Price, Gregg W. Stone
7:15 PM Case Presentation: NSTEACS Ajay J. Kirtane
7:25 PM Preloading With Oral Antiplatelet Agents: Which Agent and When? Matthew J. Price
7:31 PM Role of Cangrelor in NSTEACS: Should All Patients Receive It? Gregg W. Stone
7:40 PM GP IIb/IIIa Inhibitors in NSTEACS: Where Do We Stand? Duane S. Pinto
7:46 PM Moderated Case Discussion Moderator: Ajay J. Kirtane
Interventional Management of Complex Patients: Cutting-edge Therapies for the Advanced Interventionalist (Sponsored by St. Jude Medical, Inc.) Accreditation: none
Wednesday, October 14 6:00 PM - 8:00 PM Room: Hilton Union Square, Grand Ballroom Level, Grand Ballroom A
Check-in and Reception 6:00 PM - 6:30 PM
Interventional Management of Complex Patients: Cutting-edge Technologies for the Advanced Interventionalist 6:30 PM - 8:00 PM Chairs: Ziad A. Ali, Martin B. Leon Facultys: William T. Abraham, Jonathan M. Hill
6:30 PM Welcome/Objectives Chair: Ziad A. Ali
6:33 PM What Does the Future Hold for Complex Patient Management? Ajay J. Kirtane
6:51 PM Heart Failure Interventions: Remote Hemodynamic Monitoring for the Advanced Interventional Cardiologist William T. Abraham
7:09 PM Discussion/Commentary/Transition Moderator: Martin B. Leon
7:17 PM How to Optimize PCI With OCT Ziad A. Ali
7:35 PM Why Did I Adopt OCT? Jonathan M. Hill
7:53 PM Discussion/Commentary/Transition Chair: Martin B. Leon Next-Generation DES Technology: Let the Future Begin! (Sponsored by the Cardiovascular Research Foundation) (Supported by Abbott, Amaranth Medical, Inc., Elixir Medical Corporation, Medtronic, Inc., Minvasys, REVA Medical, Inc. and Tryton Medical, Inc.) Accreditation: none
Wednesday, October 14 6:00 PM - 8:00 PM Room: Hilton Union Square, Ballroom Level, Continental Ballroom 1-4
Chairs: Martin B. Leon, Gregg W. Stone Facultys: Alexandre Abizaid, Jose de Ribamar Costa Jr, Juan F. Granada, Marie-Claude Morice, Patrick W. Serruys, Ron Waksman
Check-in and Reception 6:00 PM - 6:30 PM
Part I. Dedicated Designs 6:30 PM - 6:45 PM Moderator: Martin B. Leon Discussants: Alexandre Abizaid, Jose de Ribamar Costa Jr, Juan F. Granada, Marie-Claude Morice, Patrick W. Serruys, Gregg W. Stone, Ron Waksman
6:30 PM Customized Stents to Treat Different Anatomical and Clinical Scenarios: Bifurcations, Myocardial Infarction Small Vessels, and More Martin B. Leon
6:40 PM Roundtable Discussion With Audience Q&A
Part II. The Polymer-Free Era Has Begun 6:45 PM - 7:10 PM Moderator: Gregg W. Stone Discussants: Alexandre Abizaid, Jose de Ribamar Costa Jr, Juan F. Granada, Martin B. Leon, Marie-Claude Morice, Patrick W. Serruys, Ron Waksman
6:45 PM BioFreedom and LEADERS FREE: Are the Results Practice Changing? Marie-Claude Morice
6:55 PM The Drug-Filled Stent and the Start of RevElution Gregg W. Stone
7:02 PM Roundtable Discussion With Audience Q&A
Part III. Will the Future Be Fully Bioresorbable? Making the Case for... 7:10 PM - 8:00 PM Moderator: Marie-Claude Morice Discussants: Alexandre Abizaid, Jose de Ribamar Costa Jr, Juan F. Granada, Martin B. Leon, Patrick W. Serruys, Gregg W. Stone, Ron Waksman
7:10 PM Proven Outcomes (Absorb) Patrick W. Serruys
7:17 PM Thin Struts With Self-Correcting Property (DESolve) Alexandre Abizaid
7:24 PM Radiopacity (Fantom) Jose de Ribamar Costa Jr
7:31 PM Metallic-DES–Like Performance (DREAMS) Ron Waksman
7:38 PM Optimized Polymer (AMARANTH) Juan F. Granada
7:45 PM Roundtable Discussion With Audience Q&A
Interactive Technology Center: Hands on Hearts Accreditation: none
Wednesday, October 14 8:00 AM - 2:00 PM Room: Moscone North, Lower Level, Hall D
Hands on Hearts 8:00 AM - 2:00 PM Discussants: Tobias Koppara, Robert Kutys, Elena Ladich, Michelle Olson, Maria E. Romero
ITC and Demonstration Theater - Complex PCI Technologies Accreditation: none
Wednesday, October 14 9:00 AM - 1:50 PM Room: Moscone North, Lower Level, Hall D
Complex Coronary Interventions - The Interventional Toolbox: Hands-on Technology Demonstration Live Ex Vivo Model Device Technique Demonstration 9:00 AM - 2:00 PM Moderators: Dimitri Karmpaliotis, William Nicholson 9:00 AM Hands on Workshop/Simulations
9:30 AM Real-Time Wiring demonstration illustrating different properties of different wires on an ETOS model (Focus on Gaia wires, Confianza Pro 12, MB 6, Pilot 200 and Fielder XT) Ashish Pershad
9:50 AM Real-Time Crossboss and Stingray Demonstration on a model R. Michael Wyman
10:10 AM Real-Time Retrograde Collateral Wiring, Microcatheter Manipulation and Wire Externalization on a Model Stéphane Rinfret
10:30 AM Interactive Tutorial: Hemodynamic Training for the Interventionalist Daniel Burkhoff
11:00 AM Moderated Discussion with Audience Q&A
11:10 AM Rotational Atherectomy Jasvindar Singh
11:20 AM Moderated Discussion with Audience Q&A
11:30 AM Orbital Atherectomy Nirat Beohar
11:40 AM Moderated Discussion with Audience Q&A
11:50 AM Laser Atherectomy Jeffrey W. Moses
12:00 PM Moderated Discussion with Audience Q&A
12:10 PM Understanding Anatomy-Device Interactions of Different Bifurcation Stent Techniques: Insights From the Visible Heart Lab Ziad A. Ali, Francesco Burzotta, Azeem Latib
12:50 PM IVUS in CTOs Dimitri Karmpaliotis
1:20 PM Guide Extension Catheters in Complex PCI Dimitri Karmpaliotis
1:40 PM Moderated Discussion With Audience Q&A
CRF Pavilion Program Accreditation: none Wednesday, October 14 9:00 AM - 12:00 PM Room: Moscone South, Lower Level, CRF Pavilion
CRF Pavilion 9:00 AM - 12:00 PM
9:00 AM Live Stream Live Case from Structural Theatre: Live Cases: Heart Failure (V- wave)/Mitral/Tricuspid With Heart Center Bonn, University Hospital Bonn, Bonn, Germany
10:30 AM Discussion With International Partners Mirvat Alasnag, Jose L. Leiva-Pons
11:00 AM Skirball Center for Innovation and Diagnostic and Interventional Cardiology Ad Interview Key Opinion Leaders
Meet the Trialists III Accreditation: CME/CNE
Wednesday, October 14 2:00 PM - 3:15 PM Room: Moscone West, 3rd Floor, Room 3000
Meet the Trialists III 2:00 PM - 3:15 PM Moderator: Cindy L. Grines Discussants: David F. Kong, Binita Shah, Jan Tijssen
2:00 PM ISAR-DESIRE 4: A Prospective Randomized Trial of Plaque Modification With a Scoring Balloon During Drug-Coated Balloon Treatment of Coronary In-Stent Restenosis Robert A. Byrne
2:05 PM Roundtable Discussion With Audience Q&A
2:15 PM PANDA III: A Prospective Randomized Trial of Two Sirolimus-Eluting Bioresorbable- Polymer-Based Metallic Stents With Varying Elution and Absorption Kinetics Bo Xu
2:20 PM Roundtable Discussion With Audience Q&A
2:30 PM TUXEDO: A Prospective Randomized Trial of Paclitaxel-Eluting vs Everolimus-Eluting Stents in Diabetic Patients With Coronary Artery Disease Upendra Kaul
2:35 PM Roundtable Discussion With Audience Q&A
2:45 PM LEADERS FREE: A Prospective, Double-blind Randomized Trial of a Polymer-Free Biolimus-Eluting Stent Versus Bare Metal Stents in Patients With Coronary Artery Disease at High Risk for Bleeding Philip M. Urban
2:50 PM Roundtable Discussion With Audience Q&A
3:00 PM IN.PACT SFA: A Prospective Randomized Trial of a Drug-Coated Balloon for Femoropopliteal Lesions - Two-Year Outcomes John R. Laird Jr
3:05 PM Roundtable Discussion With Audience Q&A
Thursday, October 15, 2015
Main Arena IV, Thursday, Oct. 15 Accreditation: CME/CNE
Thursday, October 15 8:00 AM - 2:00 PM Room: Moscone South, Esplanade Level, Main Arena
Plenary Session XXIII. Live Cases 7: Aortic Valve and Structural Heart Disease 8:00 AM - 9:30 AM Live Case Moderator: Martin B. Leon Live Case Co-Moderator: Antonio Colombo Live Case Discussants: Shmuel Banai, Mauricio G. Cohen, Isaac George, Rebecca T. Hahn, Raj Makkar, Stephen R. Ramee, Mark Reisman, Wilson Y. Szeto, Grayson H. Wheatley, Mathew Williams, Adam Witkowski Digital Moderator: Scott Lim Digital Panelists: Pawel E. Buszman, Anna Sonia Petronio, Flavio L. Ribichini, S. Chiu Wong
8:00 AM Rabin Medical Center, Petach Tikva, Israel: Transcatheter Mitral Valve Replacement Live Case Operators: Assali, Abid, MD, Gabriel Greenberg, MD, Ran Kornowski, Eli I. Lev, Hana Vaknin Assa, MD
8:45 AM St. Paul's Hospital, Vancouver, Canada: Transcatheter Mitral Valve Replacement Live Case Operators: Anson Cheung, John G. Webb, David A. Wood
Plenary Session XXIV. Hot Topics 4: Innovation Highlights at TCT 2015 9:30 AM - 10:00 AM Moderators: Alexandre Abizaid, Juan F. Granada Digital Moderator: Charles J. Davidson Digital Panelists: Chuck Simonton, Marvin J. Slepian, Frederick G. St. Goar, Alan C. Yeung Discussants: Maurice Buchbinder, Daniel Burkhoff, Louis A. Cannon, Peter J. Fitzgerald, Julio C. Palmaz, Martin T. Rothman, Tamir Wolf, Paul G. Yock
9:30 AM The TCT 2015 Innovation Award Competition: Session Highlights and Winners Announcement Juan F. Granada 9:37 AM Shark Tank Innovation Award Competition Winner (Presentation) TBA
9:41 AM Shark Tank Innovation Award Competition Winner (Presentation) TBA
9:45 AM Roundtable Discussion With Audience Q&A
Plenary Session XXV. Clinically Oriented Case-Based Tutorials 4: Structural and Valvular Heart Disease 10:00 AM - 11:00 AM Moderators: Martin B. Leon, Mark Reisman Digital Moderator: Chet Rihal Digital Panelists: Stefan C. Bertog, Andrejs Erglis, Sameer Gafoor, Arshad Quadri Discussants: Raoul Bonan, Ted E. Feldman, Bill J. French, James S. Gammie, Linda D. Gillam, Paul A. Grayburn, Susheel Kodali, Aung Myat, Joerg Seeburger, Gregg W. Stone
10:00 AM Severe AS + Symptoms in an 80-Year-Old With Low Surgical Risk: TAVR or Surgery? Case Presenter: Axel Linke
10:05 AM Severe AS + Symptoms in an 80-Year-Old With Low Surgical Risk: TAVR or Surgery? Focused Commentary Susheel Kodali
10:10 AM Roundtable Discussion With Audience Q&A
10:20 AM Severe Functional MR + Symptoms With Slightly Reduced LVEF (45%) and Moderate Surgical Risk: Treatment Options Case Presenter: Olaf Franzen
10:25 AM Severe Functional MR + Symptoms With Slightly Reduced LVEF (45%) and Moderate Surgical Risk: Treatment Options – Focused Commentary Alec S. Vahanian
10:30 AM Roundtable Discussion With Audience Q&A
10:40 AM LAA Closure vs Pharmacotherapy (Including NOACs) in a Patient With AF and Intermediate Risk of Bleeding Case Presenter: Brij Maini
10:45 AM LAA Closure vs Pharmacotherapy (Including NOACs) in a Patient With AF and Intermediate Risk of Bleeding – Focused Commentary Martin W Bergmann
10:50 AM Roundtable Discussion With Audience Q&A
Plenary Session XXVI. Late-Breaking Clinical Trials 4 11:00 AM - 12:00 PM Moderators: Martin B. Leon, Jeffrey J. Popma Digital Moderator: Mayra Guerrero Digital Panelists: Zahid Amin, Paul H. Kramer, Giuseppe Tarantini, Torsten P. Vahl Discussants: Stephen J.D. Brecker, John D. Carroll, Hans R. Figulla, Howard C. Herrmann, Thierry Lefevre, Reginald I. Low, Manuel Pan, Mark Reisman, Robert J. Sommer, Wilson Y. Szeto
11:00 AM BRAVO 3: A Prospective Randomized Trial of Bivalirudin Versus Heparin in Patients Undergoing Transcatheter Aortic Valve Replacement Thierry Lefevre
11:12 AM Roundtable Discussion With Audience Q&A
11:24 AM SAPIEN 3: Evaluation of a Balloon-Expandable Transcatheter Aortic Valve in High-Risk and Inoperable Patients With Aortic Stenosis – One-Year Outcomes Howard C. Herrmann
11:34 AM Roundtable Discussion With Audience Q&A
11:40 AM RESPECT: A Prospective Randomized Trial of PFO Closure in Patients With Cryptogenic Stroke – Long-term Results John D. Carroll
11:50 AM Roundtable Discussion With Audience Q&A
Plenary Session XXVII. First Report Investigations 4 12:00 PM - 12:30 PM Moderators: Jeroen J. Bax, Alec S. Vahanian Digital Moderator: George S. Hanzel Digital Panelists: Anita Asgar, Raoul Bonan, Nicola Corvaja, Augusto D. Pichard Discussants: Alexandre Abizaid, David L. Brown, Danny Dvir, Philippe Généreux, Karel T. Koch, Axel Linke, Tomohiko Taniguchi, TBAMark A. de Belder
12:00 PM Evaluation of Initial Surgical Versus Conservative Strategies in Patients With Asymptomatic Severe Aortic Stenosis Tomohiko Taniguchi
12:08 PM Roundtable Discussion With Audience Q&A
12:15 PM PARTNER II Valve-in-Valve Registry: Evaluation of a Balloon-Expandable Transcatheter Aortic Valve in Patients With Failed Bioprosthetic Surgical Aortic Valves Danny Dvir
12:23 PM Roundtable Discussion With Audience Q&A
Plenary Session XXVIII. Live Cases 8: Aortic Valve, Structural Heart, and Peripheral Vascular Disease 12:30 PM - 2:00 PM Live Case Moderator: Martin B. Leon Live Case Co-Moderator: D. Christopher Metzger Live Case Discussants: David J. Cohen, Danny Dvir, Sameer Gafoor, Lawrence A. Garcia, Jonathon A. Leipsic, Reginald I. Low, Constantino S. Pena, Stefan Sack, Paul Sorajja, Rodney White, Thomas Zeller Digital Moderator: Azeem Latib Digital Panelists: Philipp Blanke, Goran K. Olivecrona, Marco A. Perin, Stephen R. Ramee
12:30 PM St. Paul's Hospital, Vancouver, Canada: TAVR Live Case Operators: Anson Cheung, John G. Webb, David A. Wood
1:15 PM UC Davis Medical Center, Sacramento, CA: Endovascular Live Case Operators: John Carson, MD, John R. Laird Jr, Gagan Singh, MD, Jeffrey Southard, MD
Coronary Theater IV, Thursday, Oct. 15 Accreditation: CNE
Thursday, October 15 8:00 AM - 12:00 PM Room: Moscone North, Lower Level, Hall D
Session I. Live Cases: Coronary Imaging and Physiology Guidance 8:00 AM - 10:00 AM Live Case Moderator: William F. Fearon Live Case Co-Moderator: Bernard De Bruyne Live Case Discussants: Takashi Akasaka, John McB. Hodgson, Niels R. Holm, Allen Jeremias, Nils Johnson, Mamas Mamas, Evelyn S. Regar, Jonathan M. Tobis, Tim P. van de Hoef Digital Moderator: Gary S. Mintz Digital Panelists: Adriano Caixeta, Hyo-Soo Kim, Eugenia Nikolsky, Wojtek Wojakowski
8:00 AM Imperial College Healthcare NHS Trust, Hammersmith Hospital, London, United Kingdom Live Case Operators: Chris Baker, Justin E. Davies, Iqbal Saeed Malik, Sayan Sen
9:00 AM Rabin Medical Center, Petach Tikva, Israel Live Case Operators: Assali Abid, MD, Gabriel Greenberg, MD, Ran Kornowski, Eli I. Lev, Hana Vankin-Assa, MD
Session II. Live Cases: Coronary Imaging and Physiology Guidance 10:00 AM - 12:00 PM Live Case Moderator: Giora Weisz Live Case Co-Moderator: Akiko Maehara Live Case Discussants: Ziad A. Ali, Jose de Ribamar Costa Jr, Gerard Finet, Kishore J. Harjai, Massoud A. Leesar, Ryan D. Madder, Masato Nakamura, Robert J. Russo, Junya Shite Digital Moderator: Habib Samady Digital Panelists: Philippe L. L'Allier, Yoshinobu Onuma, Pim A.L. Tonino, Jose M. de la Torre Hernandez
10:00 AM Imperial College Healthcare NHS Trust, Hammersmith Hospital, London, United Kingdom Live Case Operators: Chris Baker, Justin E. Davies, Iqbal Saeed Malik, Sayan Sen
11:00 AM Rabin Medical Center, Petach Tikva, Israel Live Case Operators: Assali, Abid, MD, Ran Kornowski, Eli I. Lev, Hana Vaknin Assa, MD Gabriel Greenberg, MD Endovascular Theater II, Thursday, Oct. 15 Accreditation: CME/CNE
Thursday, October 15 8:00 AM - 12:00 PM Room: Moscone North, Lower Level, Hall D
Session I. Live Cases: Endovascular and Neurovascular Interventions 8:00 AM - 10:00 AM Live Case Moderator: Barry T. Katzen Live Case Co-Moderator: Michael D. Dake Live Case Discussants: Francesco Bedogni, Nicola Corvaja, Robert T Gerber, Leo Nelson Hopkins, Zvonimir Krajcer, Hugo F. Londero, Oscar A. Mendiz, Philip M. Meyers, Zoltan Ruzsa, Jorge Villegas Digital Moderator: Bernhard Reimers Digital Panelists: Klaus D. Mathias, Issam D. Moussa, Rajesh V Swaminathan, Marcus Thieme
8:00 AM UC Davis Medical Center, Sacramento, CA Live Case Operator: John R. Laird Jr
9:00 AM Gates Vascular Institute, Buffalo, NY Live Case Operators: Elad Levy, Adnan Siddiqui, Kenneth Snyder
Session II. Live Cases: Endovascular and Neurovascular Interventions 10:00 AM - 12:00 PM Live Case Moderator: William A. Gray Live Case Co-Moderator: Klaus D. Mathias Live Case Discussants: Dmitriy N. Feldman, Mark J. Goodwin, Michel Camille Henry, Leo Nelson Hopkins, Thomas A. Ischinger, Stephen R. Ramee, Aljoscha Rastan, Robert M. Schainfeld, Mark H. Wholey, James P. Zidar Digital Moderator: TBA Digital Panelists: Sriram S. Iyer, Gregory Mishkel, Juan C. Parodi, Ivo Petrov
10:00 AM UC Davis Medical Center, Sacramento, CA Live Case Operator: John R. Laird Jr
11:00 AM Gates Vascular Institute, Buffalo, NY Live Case Operators: Elad Levy, Adnan Siddiqui, Kenneth Snyder
Aortic Endografts and Aneurysm Repair Accreditation: CME/CNE Thursday, October 15 2:00 PM - 6:15 PM Room: Moscone West, 2nd Floor, Room 2006 - 2008
Session I. Abdominal Aneurysms and EVAR, Part 1 2:00 PM - 3:27 PM Moderators: Clifford J. Buckley, Zvonimir Krajcer Discussants: Robert A. Lookstein, Christopher K. Zarins
2:00 PM Is AAA Incidence on the Decline in the United States, Thereby Limiting the Value of Screening? Christopher K. Zarins
2:10 PM Roundtable Discussion With Audience Q&A
2:12 PM Status Report on Endovascular Aneurysm Sealing (EVAS) With Nellix: Big Promises and a Few Unknowns Clifford J. Buckley
2:22 PM Roundtable Discussion With Audience Q&A
2:24 PM Proposed Mechanisms for Proximal Neck Enlargement After EVAR: Can Devices Without Continuous Outward Force (Nellix vs Endurant) Make a Difference? Christopher K. Zarins
2:34 PM Roundtable Discussion With Audience Q&A
2:36 PM Master Class: Lessons Learned After 2000 Percutaneous EVAR (PEVAR) Procedures Zvonimir Krajcer
2:46 PM Roundtable Discussion With Audience Q&A
2:48 PM AAA Associated With Large or Aneurysmal Common Iliac Artery: Current Treatment Approaches Constantino S. Pena
2:58 PM Roundtable Discussion With Audience Q&A
3:00 PM Will Successful Adoption of Fenestrated/Branched Grafts in Complex Anatomy Improve Overall Patient Outcomes by Decreasing Off-label Usage of Standard EVAR Devices? Christopher J. Kwolek
3:10 PM Roundtable Discussion With Audience Q&A
3:12 PM Current and Future Strategies for EVAR Follow-up and Endoleak Surveillance Robert A. Lookstein
3:22 PM Roundtable Discussion With Q&A
Session II. Abdominal Aneurysms and EVAR, Part 2 3:27 PM - 4:27 PM Moderators: Jacques Busquet, Christopher K. Zarins Discussants: Clifford J. Buckley, Frank J. Criado, Christopher J. Kwolek 3:27 PM Endo-Tension and Its Implications: A Primer Jacques Busquet
3:37 PM Roundtable Discussion With Audience Q&A
3:39 PM Graft Limb Occlusion After EVAR: A Historical Footnote? Frank J. Criado
3:49 PM Roundtable Discussion With Audience Q&A
3:51 PM Endovascular Repair of Pararenal and Thoracoabdominal Aneurysms: Does Open Surgery Remain a Competitive Treatment Option? Christopher J. Kwolek
4:01 PM Roundtable Discussion With Audience
4:03 PM EVAR Treatment of Ruptured AAA: Current Review and Recommendations Clifford J. Buckley
4:13 PM Roundtable Discussion With Q&A
4:15 PM The Future Is Now: Robotic EVAR's Rationale and Potential Constantino S. Pena
4:25 PM Roundtable Discussion With Q&A
Session III. Thoracic Aneurysms and TEVAR 4:27 PM - 6:15 PM Moderators: Wilson Y. Szeto, Rodney White Discussants: Frank J. Criado, Michael D. Dake, Zvonimir Krajcer, Firas F Mussa, Grayson H. Wheatley
4:27 PM A Proposal: All Type B Aortic Dissection Are "Unstable" and Deserving of TEVAR Intervention Firas F Mussa
4:37 PM Roundtable Discussion With Q&A
4:39 PM The Petticoat Strategy: Results of Bare-Metal Stent Extension for Thoracic Endografts in Type B Dissections Grayson H. Wheatley
4:49 PM Roundtable Discussion With Audience Q&A
4:51 PM Endovascular Strategies for Treatment of Juxta-Subclavian and Juxta-Celiac Descending TAA Frank J. Criado
5:01 PM Roundtable Discussion With Audience Q&A
5:03 PM Neurological Complications of TEVAR: Prevention and Management Michael D. Dake
5:13 PM Roundtable Discussion With Audience Q&A
5:15 PM Use of Endoanchors to Prevent or Treat Gutter-Related Endoleaks After Use of Chimneys and Parallel Grafts Zvonimir Krajcer
5:25 PM Roundtable Discussion With Audience Q&A
5:27 PM Current Update on Treatment of Blunt Thoracic Aortic Injury (BTAI) Rodney White
5:37 PM Roundtable Discussion With Audience Q&A
5:39 PM Role of Frozen Elephant Trunk and Other Hybrid Combinations for Treatment of Complex Thoracic Aortic Pathologies Wilson Y. Szeto
5:49 PM Roundtable Discussion With Audience Q&A
5:51 PM Endovascular Solutions for the Ascending Aorta Firas F Mussa
6:01 PM Roundtable Discussion With Audience Q&A
6:03 PM Thoracic Case Presentation: Treating Complex Chronic Dissections Wilson Y. Szeto
6:13 PM Roundtable Discussion With Audience Q&A
Bioresorbable Vascular Scaffolds, Part 2 Accreditation: CME
Thursday, October 15 2:00 PM - 6:00 PM Room: Moscone West, 3rd Floor, Room 3001 - 3005
Session I. Emerging Results With Next-Generation Devices 2:00 PM - 3:42 PM Moderators: Alexandre Abizaid, Pieter C. Smits Discussants: Jose de Ribamar Costa Jr, Upendra Kaul, Jacques J. Koolen, Thomas F. Luscher, Yoshinobu Onuma
2:00 PM Featured Lecture: The Biotronik Magnesium DREAMS Scaffold: Pivotal BIOSOLVE-II Results Michael Haude
2:10 PM Elixir DESolve: Differentiating Features and Latest 150-uM and 100-uM Results Alexandre Abizaid
2:20 PM REVA Fantom: Differentiating Features and FIM Insights Jose de Ribamar Costa Jr
2:27 PM Amaranth: Differentiating Features and Clinical Update Juan F. Granada
2:34 PM Manli Mirage BRS: Differentiating Features and Clinical Update Patrick W. Serruys
2:41 PM Meril Life Sciences MeRes: Differentiating Features and Clinical Update Martin B. Leon
2:48 PM Terumo ART: Differentiating Features and Clinical Update Antoine Lafont
2:55 PM Boston Scientific FAST BRS: Differentiating Features and Clinical Update Ian T. Meredith
3:02 PM Lepu NeoVas: Differentiating Features and Clinical Update Yaling Han
3:09 PM The XINSORB BRS: Differentiating Features and Clinical Update Lei Ge
3:16 PM The Lifetech Iron-Based BRS: Differentiating Features and Challenges Deyuan Zhang
3:23 PM The Biolute BRS: Differentiating Features and Clinical Update Dinesh Shah
3:30 PM Roundtable Discussion With Audience Q&A
Session II. Learning From Experience: BRS Cases 3:42 PM - 5:30 PM Moderators: David W.M. Muller, Ashok Seth Discussants: Adriano Caixeta, Talib Majwal, D. Christopher Metzger, Jan J. Piek, Lorenz Raber, Afzalur Rahman
3:42 PM BRS in Long Lesions (With Overlap) Case Presenter: Giuseppe Tarantini
3:48 PM Roundtable Discussion With Audience Q&A
3:51 PM BRS in Multivessel Disease Case Presenter: Robert-Jan van Geuns
3:57 PM Roundtable Discussion With Audience Q&A
4:00 PM BRS in CTOs Case Presenter: Sunao Nakamura
4:06 PM Roundtable Discussion With Audience Q&A 4:09 PM BRS in Bifurcations 1: Provisional Approach Case Presenter: Vladimir Dzavik
4:15 PM Roundtable Discussion With Audience Q&A
4:18 PM BRS in Bifurcations 2: Two-Device Approaches Case Presenter: Antonio L. Bartorelli
4:24 PM Roundtable Discussion With Audience Q&A
4:27 PM BRS in Calcified Lesions Case Presenter: Gert Richardt
4:33 PM Roundtable Discussion With Audience Q&A
4:36 PM BRS in In-Stent Restenosis Case Presenter: Kenneth Chin
4:42 PM Roundtable Discussion With Audience Q&A
4:45 PM BRS in Left Main Intervention Case Presenter: Davide Capodanno
4:51 PM Roundtable Discussion With Audience Q&A
4:54 PM BRS in STEMI Case Presenter: Huay Cheem Tan
5:00 PM Roundtable Discussion With Audience Q&A
5:03 PM How to Use Imaging Guidance During BRS Implantation Case Presenter: Evelyn S. Regar
5:09 PM Roundtable Discussion With Audience Q&A
5:12 PM My Greatest BRS Long-term Success Case Presenter: Jochen Wöhrle
5:18 PM Roundtable Discussion With Audience Q&A
5:21 PM My Most Regrettable BRS Complication Case Presenter: Massimo Napodano
5:27 PM Roundtable Discussion With Audience Q&A
Session III. Closing Debate: The Most Important Question 5:30 PM - 6:00 PM Moderators: Thomas F. Luscher, Gregg W. Stone Discussants: Alaide Chieffo, Upendra Kaul, Azeem Latib, Sundeep Mishra, Serban Puricel
5:30 PM Closing Debate Pre-vote: Should Our Patients Receive BRS Rather Than Metallic DES TODAY? Poll Moderators: Thomas F. Luscher, Gregg W. Stone 5:32 PM Debate: Should Our Patients Receive BRS Rather Than Metallic DES TODAY? Yes, the 1-Year Results Are Very Close, and the Late Outcomes Will Be Superior – Our Patients Can’t Wait for the Proof! Ashok Seth
5:39 PM Debate: Should Our Patients Receive BRS Rather Than Metallic DES TODAY? No, More Expensive, More Difficult to Use, and Slightly Worse 1-Year Outcomes – I’ll Wait for Proof of Late Superiority (or the Next Generation)! Robert A. Byrne
5:46 PM Roundtable Discussion With Audience Q&A
5:51 PM Closing Post-debate Vote (Who Won?): Should Our Patients Receive BRS Rather Than Metallic DES TODAY? Poll Moderators: Thomas F. Luscher, Gregg W. Stone
5:53 PM Roundtable Discussion With Audience Q&A
Cell Therapy and Cardiovascular Repair: Discovery and Debate Accreditation: none
Thursday, October 15 2:00 PM - 6:00 PM Room: Moscone West, 3rd Floor, Room 3006 - 3008
Session I. Cardiac Regenerative Medicine: Crisis? What Crisis? 2:00 PM - 2:50 PM Moderators: Francisco Fdez-Aviles, Timothy D. Henry Discussants: Marc S. Penn, Felipe Prosper, Ricardo Sanz-Ruiz, Jay H Traverse
2:00 PM Session Introduction Francisco Fdez-Aviles, Timothy D. Henry
2:03 PM Cell-Based Therapies to Prevent and Cure Heart Failure: More Than an Adventure Douglas W. Losordo
2:18 PM Stem Cells in Biology of the Adult Myocardium: Are Biomaterials the Missing Link? Jay H Traverse
2:30 PM Disappointing Clinical Trial Experiences to Date: Should We Continue? In Which Setting? How? Francisco Fdez-Aviles
2:42 PM Roundtable Discussion With Audience Q&A Session II. Stem Cell Advances: Targeting Heart Failure 2:50 PM - 3:57 PM Moderators: Nabil Dib, Philippe Menasché Discussants: Andreu M Climent, Douglas W. Losordo, Emerson C. Perin, Jay H Traverse
2:50 PM Pre-debate Vote: In Patients With End-stage Coronary Artery Disease With Ischemia and Scar, Which Cell Type will Work Best? Poll Moderator: Timothy D. Henry
2:53 PM In Patients With End-stage Coronary Artery Disease With Ischemia and Scar, Which Cell Type Will Work Best? Cardiopoietic Commitment Is the Key! Amit Patel
3:03 PM In Patients With End-stage Coronary Artery Disease With Ischemia and Scar, Which Cell Type Will Work Best? Combination of Cells for Additive Effects: This Is the Key! Jay H Traverse
3:13 PM In Patients With End-stage Coronary Artery Disease With Ischemia and Scar, Which Cell Type Will Work Best? Cardiac Progenitor Cells Are the Only One! Timothy D. Henry
3:23 PM In Patients With End-stage Coronary Artery Disease With Ischemia and Scar, Which Cell Type Will Work Best? No Cell Works. Genes are the Answer. Marc S. Penn
3:33 PM Post-debate Vote (Who Won?): In Patients With End-stage Coronary Artery Disease With Ischemia and Scar, Which Cell Type will Work Best? Poll Moderator: Timothy D. Henry
3:35 PM Roundtable Discussion With Audience Q&A
3:39 PM Stem Cell–Based Ablation for Ventricular Arrhythmias Angel Arenal
3:51 PM Roundtable Discussion With Audience Q&A
Session III. Cardiac Tissue Engineering (Beyond the Cell): There Is No Tissue Without Structure 3:57 PM - 4:46 PM Moderators: Francisco Fdez-Aviles, Emerson C. Perin Discussants: Andreu M Climent, Nabil Dib, Ricardo Sanz-Ruiz
3:57 PM Pre-debate Vote: Is It Necessary to Implant 3-D Cardiac Structures? In Which Setting? Poll Moderator: Francisco Fdez-Aviles
3:59 PM Debate: Is It Necessary to Implant 3-D Cardiac Structures? In Which Setting? Yes, With Bioartificial Matrices, Which Are Available and Versatile! Felipe Prosper
4:09 PM Debate: Is It Necessary to Implant 3-D Cardiac Structures? In Which Setting? Yes, With Cadaveric Matrices – Native Myocardial Architecture Is Mandatory! Doris A. Taylor 4:19 PM Debate: Is It Necessary to Implant 3-D Cardiac Structures? In Which Setting? But Power Is Nothing Without Control – Electromechanical Engraftment! Andreu M Climent
4:29 PM Debate: Is It Necessary to Implant 3-D Cardiac Structures? In Which Setting? With Micro and Nanotechnology in Cardiovascular Tissue Engineering! Kevin E Healy
4:39 PM Post-debate Vote (Who Won?): Is It Necessary to Implant 3-D Cardiac Structures? In Which Setting? Poll Moderator: Francisco Fdez-Aviles
4:41 PM Roundtable Discussion With Audience Q&A
Session IV. Stem Cell Therapy Clinical Trials: Yes, We Can! 4:46 PM - 6:00 PM Moderators: Francisco Fdez-Aviles, Timothy D. Henry Discussants: Henricus J. Duckers, Douglas W. Losordo, Ricardo Sanz-Ruiz
4:46 PM Pre-debate Vote 1: Are We Really Ready for Phase III Trials in Acute Myocardial Infarction? Poll Moderator: Timothy D. Henry
4:47 PM Pre-debate Vote 2: Are We Really Ready for Phase III Trials in Chronic Heart Failure? Poll Moderator: Timothy D. Henry
4:48 PM Pre-debate Vote 3: Are We Really Ready for Phase III Trials in Refractory Angina? Poll Moderator: Timothy D. Henry
4:49 PM Pre-debate Vote 4: Are We Really Ready for Phase III Trials in Limb Ischemia? Poll Moderator: Timothy D. Henry
4:50 PM Debate: Are We Really Ready for Phase III Trials? Yes, in STEMI – Bone Marrow Mononuclear Fraction Is Ready, and Other Options Are Coming! Ricardo Sanz-Ruiz
5:00 PM Debate: Are We Really Ready for Phase III Trials? Yes, Mesenchymal Cells Are Ready to Be Tested for Prevention and Treatment of Chronic Ischemic and Nonischemic Heart Failure! Emerson C. Perin
5:10 PM Debate: Are We Really Ready for Phase III Trials? For Refractory Angina There Are Knowns and Unknowns! Timothy D. Henry
5:20 PM Debate: Are We Really Ready for Phase III Trials? For Limb Ischemia There Are Knowns and Unknowns! Amit Patel
5:30 PM Post-debate Vote: Did We Change Any Minds? Poll Moderator: Timothy D. Henry
5:31 PM Post-debate Vote 1 (Who Won?): Are We Really Ready for Phase III Trials in Acute Myocardial Infarction? Poll Moderator: Timothy D. Henry
5:32 PM Post-debate Vote 2 (Who Won?): Are We Really Ready for Phase III Trials in Chronic Heart Failure? Poll Moderator: Timothy D. Henry
5:33 PM Post-debate Vote 3 (Who Won?): Are We Really Ready for Phase III Trials in Refractory Angina? Poll Moderator: Timothy D. Henry
5:34 PM Post-debate Vote 4 (Who Won?): Are We Really Ready for Phase III Trials In Limb Ischemia? Poll Moderator: Timothy D. Henry
5:35 PM Roundtable Discussion With Audience Q&A
5:40 PM First-in-Man Experience With Human Embryonic Stem Cell-Derived Progenitors for Heart Failure Philippe Menasché
5:52 PM Roundtable Discussion With Audience Q&A
Hypertrophic Cardiomyopathy and Septal Ablation Accreditation: CME/CNE
Thursday, October 15 2:00 PM - 5:50 PM Room: Moscone West, 3rd Floor, Room 3002 - 3004
Session I. Hypertrophic Cardiomyopathy: Diagnosis and Management 2:00 PM - 3:50 PM Moderators: John S. Douglas Jr, Sherif F. Nagueh Discussants: Jorge Gaspar, Kishore J. Harjai, Mark V. Sherrid
2:00 PM Pathophysiology and Natural History Mark V. Sherrid
2:20 PM Medical Management: Agents and Effectiveness Mark V. Sherrid
2:35 PM Contemporary Surgical Approaches: Indications and Outcomes Sherif F. Nagueh
2:50 PM Indications for Septal Reduction Therapy Sherif F. Nagueh
3:05 PM CTA for Procedure Planning Jorge Gaspar
3:15 PM HCM Ablation Step-by-Step Approach, Complications, and Long-term Outcomes Valerian Fernandes
3:35 PM Roundtable Discussion With Audience Q&A
Session II. Hypertrophic Cardiomyopathy: Debates 3:50 PM - 5:05 PM Moderators: Srihari S. Naidu, Paul Sorajja Discussants: Valerian Fernandes, Antoine Lafont, John C. Messenger
3:50 PM Pre-debate Vote: Does Alcohol Septal Ablation Increase the Risk for Sudden Cardiac Death? Poll Moderators: Srihari S. Naidu, Paul Sorajja
3:52 PM Debate 1: Does Alcohol Septal Ablation Increase the Risk for Sudden Cardiac Death? Yes, Definitely! Valerian Fernandes
3:59 PM Debate 1: Does Alcohol Septal Ablation Increase the Risk for Sudden Cardiac Death? No, It Does Not! Paul Sorajja
4:06 PM Roundtable Discussion With Audience Q&A
4:13 PM Vote Does Alcohol Septal Ablation Increase the Risk for Sudden Cardiac Death? Poll Moderators: Srihari S. Naidu, Paul Sorajja
4:15 PM Vote: Is Surgery the Gold Standard for Most Cases of HCM? Poll Moderator: Srihari S. Naidu
4:17 PM Alcohol Septal Ablation Is the Choice for Most Cases! Srihari S. Naidu
4:30 PM Roundtable Discussion With Audience Q&A
4:38 PM Vote: Is Surgery the Gold Standard for Most Cases of HCM? Yes, Without Doubt! Poll Moderator: Srihari S. Naidu
4:40 PM Vote: Which Age Group Should Be Referred for Alcohol Septal Ablation? Poll Moderator: Srihari S. Naidu
4:42 PM Debate 3: Which Age Group Should Be Referred for Alcohol Septal Ablation? The Procedure Is Equally Effective at All Ages! George S. Hanzel
4:49 PM Debate 3: Which Age Group Should Be Referred for Alcohol Septal Ablation? The Procedure Should Be Offered to Elderly Patients Only! John S. Douglas Jr
4:56 PM Roundtable Discussion With Audience Q&A
5:03 PM Poll: Should Age Be a Factor in Considering Use of Alcohol Septal Ablation? Post- debate 3 Vote (Who Won?): Which Age Group Should Be Referred for Alcohol Septal Ablation? Poll Moderator: Srihari S. Naidu
Session III. HCM Cases: Diagnostic and Management Questions 5:05 PM - 5:50 PM Moderators: Dominique Himbert, Paul Sorajja Discussants: Jorge Gaspar, Carey D. Kimmelstiel, Augusto D. Pichard
5:05 PM Who to Restrict for Athletic Participation Paul Sorajja
5:15 PM Alcohol Septal Ablation: My Worst Complication (and What I Wish I Did Differently) Carey D. Kimmelstiel
5:25 PM Heart Block at Day 3 After Alcohol Septal Ablation. What to Do Now? John C. Messenger
5:35 PM Roundtable Discussion With Audience Q&A
The Left Main and Bifurcation Summit, Part 2: Left Main Intervention Accreditation: CME/CNE
Thursday, October 15 2:00 PM - 6:10 PM Room: Moscone West, 2nd Floor, Room 2020 - 2024
Session I. Left Main PCI vs CABG 2:00 PM - 2:55 PM Moderators: Davide Capodanno, Gregg W. Stone Discussants: Shao-Liang Chen, Stuart J. Head, Verghese Mathew, Bernhard Reimers, Grayson H. Wheatley
2:00 PM Left Main PCI vs CABG: Fifteen-Year Results From the Asan Medical Center and 5- Year Results From PRECOMBAT Jung-Min Ahn
2:10 PM PCI vs CABG for LM Disease: New Insights From Syntax LM to Help Choose Patrick W. Serruys 2:18 PM Long-term Results of PCI vs CABG in 4,046 Patients With Left Main Disease: Fu Wai Experience Bo Xu
2:26 PM Who Should Undergo LM PCI Today? US and EU Guidelines and AUC Review Ajay J. Kirtane
2:34 PM Roundtable Discussion With Audience Q&A
2:44 PM Case Introduction: PCI or CABG? A Clinically High-Risk and Anatomically Complex Left Main Patient Case Presenter: Nicholas J. Lembo
2:47 PM Discussion: How Should This Patient Be Treated?
2:52 PM Case Resolution: How We Treated a Clinically High-Risk and Anatomically Complex Left Main Patient (With Long-term Follow-up) Case Presenter: Nicholas J. Lembo
Session II. Left Main PCI: The Basics 2:55 PM - 3:59 PM Moderator: David E. Kandzari Poll Moderator: Duk-Woo Park Discussants: Bagrat Alekyan, David Antoniucci, Evald H. Christiansen, Vasim Farooq, Akiko Maehara, Hitoshi Matsuo
2:55 PM How Is the Left Main Bifurcation Similar But Different From Other Bifurcations? Thierry Lefevre
3:02 PM Are All Metallic Stents Equal for LM Bifurcations? Nicolas Foin
3:09 PM Roundtable Discussion With Audience Q&A
3:14 PM Making the Case for: FFR in Left Main Disease Michalis Hamilos
3:21 PM Making the Case for: IVUS in Left Main Disease Francesco Liistro
3:28 PM Insights From OCT and IVUS in LM Bifurcations: Lessons From DOCTOR Left Main Niels R. Holm
3:35 PM Intravascular Imaging Is Not Needed: Angiography and the Finét/HK Relation Are Enough for Left Main PCI Thierry Lefevre
3:42 PM Rationale for EBC Main: LM 1 vs 2 Stents and IVUS vs No IVUS David Hildick-Smith
3:49 PM Roundtable Discussion With Audience Q&A Session III. Left Main PCI: The Technique 3:59 PM - 5:20 PM Moderators: Nicholas J. Lembo, Patrick W. Serruys Discussants: Jung-Min Ahn, Carlo Briguori, Pawel E. Buszman, Andrejs Erglis, Tejas Patel, Marco A. Perin
3:59 PM Technical Considerations in Left Main Provisional Stenting Evald H. Christiansen
4:07 PM Limitations of the Provisional Approach for Left Main Stenting Alaide Chieffo
4:14 PM Role of the Bifurcation Angle and 3-D Analysis in Informing Left Main Technique Patrick W. Serruys
4:21 PM Overview of the 2 Stent Techniques: When and Which (With Case Examples)? David E. Kandzari
4:31 PM Roundtable Discussion With Audience Q&A
4:41 PM Left Main Stent Technique and Decision Making: What We Have Learned From the MITO Study Sunao Nakamura
4:48 PM Left Main Stent Technique and Decision Making: What We Have Learned From the DELTA Registry Alaide Chieffo
4:55 PM Left Main Stent Technique and Decision Making: What We Have Learned From the ISAR LEFT Main I and II Trials Julinda Mehilli
5:02 PM When and How Should We Use a Dedicated Stent for Left Main PCI (With Case Examples)? Eulogio J. Garcia
5:10 PM Roundtable Discussion With Audience Q&A
Session IV: Learning From Left Main PCI Cases 5:20 PM - 6:10 PM Moderators: Antonio Colombo, Corrado Tamburino Discussants: Dietmar H. Glogar, Huay Cheem Tan, Marco V. Wainstein, Hadley K. Wilson, Adam Witkowski
5:20 PM Left Main PCI Case 1: Difficult LCX Access Case Presenter: Yuejin Yang
5:27 PM Roundtable Discussion With Audience Q&A
5:30 PM Left Main PCI Case 2: Complex Provisional Stenting Case Presenter: Huay Cheem Tan 5:37 PM Roundtable Discussion With Audience Q&A
5:40 PM Left Main PCI Case 3: Difficult 2-Stent Approach Case Presenter: Teguh Santoso
5:47 PM Roundtable Discussion With Audience Q&A
5:50 PM Left Main PCI Case 4: A Complex Trifurcation Case Presenter: Afzalur Rahman
5:57 PM Roundtable Discussion With Audience Q&A
6:00 PM Left Main PCI Case 5: Occluded Left Main and Cardiogenic Shock George W. Vetrovec
6:07 PM Roundtable Discussion With Audience Q&A
PCI Pharmacotherapy: Emerging and Investigational Agents Accreditation: CME/CNE
Thursday, October 15 2:00 PM - 5:50 PM Room: Moscone West, 2nd Floor, Room 2014 - 2018
Session I. Cangrelor: A Rapidly Acting, Potent IV P2Y12 Receptor Inhibitor 2:00 PM - 3:00 PM Moderators: Deepak L. Bhatt, Robert A. Harrington, Harvey D. White Discussants: John A. Ambrose, Philippe Généreux, Christopher Irobunda, Marco V. Wainstein
2:00 PM Cangrelor I: Data Essentials From the Champion Trials Deepak L. Bhatt
2:15 PM Cangrelor II: Perspectives on in Whom to Actually Use It Robert A. Harrington
2:27 PM Cangrelor III: Effects on Intraprocedural and Postprocedural Stent Thrombosis Philippe Généreux
2:36 PM Cangrelor IV: Transitioning to Oral ADP Antagonists Harvey D. White
2:45 PM Roundtable Discussion With Audience Q&A
Session II. Periprocedural Anticoagulation 3:00 PM - 4:00 PM Moderators: Carlo Briguori, Roxana Mehran Discussants: Piera Capranzano, Carey D. Kimmelstiel, Michel R. Le May, Michael S. Lee, Eugenia Nikolsky, John L. Petersen
3:00 PM The REG1 Anticoagulation System: Lessons From Factor IX Inhibitor Using RNA Aptamer Technology Roxana Mehran
3:10 PM MATRIX Trial Recap: Interaction Between Access Site and Antithrombin Choice in ACS Carlo Briguori
3:25 PM Bivalirudin Versus Unfractionated Heparin Analysis: What Is Really Best in Which Patients? Carey D. Kimmelstiel
3:40 PM Roundtable Discussion With Audience Q&A
Session III. Evolving World of Antiplatelet and Anticoagulant Therapy 4:00 PM - 5:10 PM Moderators: Eric R. Bates, Neal S. Kleiman Discussants: John A. Bittl, C. Michael Gibson, David F. Kong, Gary L. Schaer
4:00 PM Should You Bridge in Stented Patients Needing Surgery? David F. Kong
4:12 PM Vorapaxar: Lessons From the Randomized Trials in ACS and for Secondary Prevention Ori Ben-Yehuda
4:32 PM Is There a Role for Oral Anticoagulants After PCI? C. Michael Gibson
4:44 PM Roundtable Discussion With Audience Q&A
Session IV. PCSK9 Inhibitors and Other Agents 5:00 PM - 5:50 PM Moderators: Frederick Feit, C. Michael Gibson Discussants: David Antoniucci, Germano Di Sciascio, Joshua W. Knowles, Norman E. Lepor
5:00 PM The PCSK9 Inhibitor Revolution Norman E. Lepor
5:20 PM Cilostazol: When to Consider (and Is the Data Robust?) Frederick Feit
5:30 PM Statin Pretreatment Prior to PCI: Are the Effects Real? Germano Di Sciascio
5:40 PM Roundtable Discussion With Audience Q&A Radial Access and Intervention Accreditation: CME/CNE
Thursday, October 15 2:00 PM - 6:00 PM Room: Moscone West, 2nd Floor, Room 2001 - 2005
Session I. Transradial PCI: The Evidence 2:00 PM - 3:00 PM Moderators: Sanjit S. Jolly, Sunil V. Rao Discussants: Robert J. Applegate, Olivier F. Bertrand, Rajiv Gulati, Thomas A. Ischinger, Yves R. Louvard, James Nolan
2:00 PM Updated Evidence for Transradial vs Transfemoral Catheterization and PCI Ajay J. Kirtane
2:10 PM Access Site and Radiation Exposure: Radial vs Femoral Sanjit S. Jolly
2:20 PM Volume-Outcome Relationships in Transradial PCI and the Learning Curve Sunil V. Rao
2:30 PM Radial Approach and Risk of Stroke: What Are the Data? Sanjit S. Jolly
2:40 PM Does Radial Proficiency Affect Femoral Expertise? James Nolan
2:50 PM Roundtable Discussion With Audience Q&A
Session II. Transradial PCI: Controversies 3:00 PM - 4:00 PM Moderator: Olivier F. Bertrand Discussants: Robert J. Applegate, Guosheng Fu, Mamas Mamas, Alexander Grigorievich Osiev, Ramon Quesada, Sunil V. Rao, Stéphane Rinfret
3:00 PM Is There a Reason to Check for Dual Circulation Before Accessing the Radial Artery? Douglas G. Fraser
3:10 PM Can We Reduce Femoral Bailout Rates? Role of Ulnar Artery Access Sasko Kedev
3:20 PM How Can Adoption of Radial Approach Be Accelerated? Ian C. Gilchrist
3:30 PM What Is the Optimal Anticoagulant for Transradial PCI? John A. Bittl
3:40 PM Should We Be Using the Left Radial Approach in Most Patients? Alessandro Sciahbasi
3:50 PM Roundtable Discussion With Audience Q&A
Session III. Transradial PCI: Essential Techniques 4:00 PM - 5:00 PM Moderators: Philippe Généreux, Jennifer A. Tremmel Discussants: Mauricio G. Cohen, Luis A. Guzman, Narenda N. Khanna, Sudhir Rathore, Binita Shah, Adhir Shroff
4:00 PM Radial Artery Access and Hemostasis Samir B. Pancholy
4:10 PM Overcoming Challenges in Traversing the Arm and Chest Vasculature Mauricio G. Cohen
4:20 PM Bigger and Smaller: How to Upsize and Downsize Your Radial Approach Rajiv Gulati
4:30 PM Transradial Peripheral Intervention: What Is Feasible? What Equipment Do We Need? Olivier F. Bertrand
4:40 PM Common Complications of the Radial Approach and How to Deal With Them Adhir Shroff
4:50 PM Roundtable Discussion With Audience Q&A
Session IV. Transradial PCI: Complex Cases 5:00 PM - 6:00 PM Moderators: David E. Kandzari, Yves R. Louvard Discussants: Olivier F. Bertrand, Roberto Botelho, Philippe Généreux, Sanjit S. Jolly, Binita Shah, Mladen I. Vidovich
5:00 PM Complex Transradial PCI: CTO Ramon Quesada
5:10 PM “You Can’t Do That Case Radially!" "Well… I Just Did!” Case Presenter: David E. Kandzari
5:20 PM Complex Transradial Primary PCI: Case Examples of Problem Solving Case Presenter: Mauricio G. Cohen
5:30 PM Five Tips for Complex Transradial PCI and Case Examples Case Presenter: Yves R. Louvard
5:40 PM Complex Transradial PCI: Left Main and Bifurcations Case Presenter: Tejas Patel
5:50 PM Roundtable Discussion With Audience Q&A
Transcatheter Aortic Valve Therapies: Today and Tomorrow, Part 4 Accreditation: CME/CNE
Thursday, October 15 2:00 PM - 6:00 PM Room: Moscone West, 3rd Floor, Room 3007 - 3011
Session X. TAVR Complications, Part 1: Stroke and Paravalvular Regurgitation 2:00 PM - 3:12 PM Moderators: Samir R. Kapadia, Nicolas M. Van Mieghem Discussants: Adnan K. Chhatriwalla, Susheel Kodali, Ronald M. Lazar, Augusto D. Pichard, Jeffrey J. Popma, Richard Smalling, Wilson Y. Szeto, Corrado Tamburino, Alan C. Yeung
2:00 PM Stroke After TAVR 1: Reassessing Incidence (Declining), Etiologic Factors, and Remaining Controversies Samir R. Kapadia
2:10 PM Roundtable Discussion With Audience Q&A
2:15 PM Stroke After TAVR 2: Controversy 1 – Need for Cerebral Protection (Universal vs Selective) Nicolas M. Van Mieghem
2:23 PM Roundtable Discussion With Audience Q&A
2:26 PM Stroke After TAVR 3: Controversy 2 – Importance and Methods of Neurocognitive Functional Assessments Ronald M. Lazar
2:36 PM Roundtable Discussion With Audience Q&A
2:41 PM Paravalvular Regurgitation After TAVR 1: KEYNOTE LECTURE – Diagnostic Considerations, Clinical Impact, and Treatment Alternatives Susheel Kodali
2:56 PM Roundtable Discussion With Audience Q&A
3:01 PM Paravalvular Regurgitation After TAVR 2: Importance of Valve Sizing and Calcium Patterns to Predict and Prevent Paravalvular Regurgitation After TAVR Jeffrey J. Popma
3:09 PM Roundtable Discussion With Audience Q&A
Session XI. TAVR Complications, Part 2: All the Rest 3:12 PM - 4:49 PM Moderators: Isaac George, Augusto D. Pichard Discussants: G. Michael Deeb, Susheel Kodali, Azeem Latib, Stephen R. Ramee, Alec S. Vahanian, Torsten P. Vahl
3:12 PM Incidence, Significance, and Management of New-Onset Atrial Fibrillation After TAVR Alec S. Vahanian
3:20 PM Roundtable Discussion With Audience Q&A
3:23 PM Bleeding Events (Early and Late) After TAVR: Growing Importance and Often Misunderstood Philippe Généreux
3:31 PM Roundtable Discussion With Audience Q&A
3:34 PM Conduction Disturbances (New LBBB and Pacemakers) After TAVR: Frequency, Clinical Impact, and Management Considerations Susheel Kodali
3:42 PM Roundtable Discussion With Audience Q&A
3:45 PM Vascular Complications After TAVR: Changing Frequency, Clinical Impact, and Optimal Management Augusto D. Pichard
3:53 PM Roundtable Discussion With Audience Q&A
3:56 PM Valve Thrombosis After TAVR: Frequency, Clinical Recognition, and Management Azeem Latib
4:04 PM Roundtable Discussion With Audience Q&A
4:07 PM KEYNOTE LECTURE: Early Bioprosthetic Valve Leaflet Thickening – High-Resolution Imaging Observations, Clinical Implications, and Controversies Raj Makkar
4:22 PM Roundtable Discussion With Audience Q&A
4:27 PM Risks, Consequences, and Treatment of Coronary Obstruction During TAVR David Hildick-Smith
4:35 PM Roundtable Discussion With Audience Q&A
4:38 PM Anatomical and Procedural Factors Associated With Aortic Root Rupture During TAVR Isaac George
4:46 PM Roundtable Discussion With Audience Q&A
Session XII. TAVR Procedural Considerations, Including the “Minimalist” Approach 4:49 PM - 6:00 PM Moderators: Ganesh Manoharan, Mathew Williams Discussants: Saif Anwaruddin, Danny Dvir, Helene Eltchaninoff, Hemal Gada, Kendra J. Grubb, Rebecca T. Hahn, Jonathon A. Leipsic, Reginald I. Low, Wesley R. Pedersen, Nicolas M. Van Mieghem 4:49 PM Evolution of the “Minimalist” Approach: A Generalizable Strategy to Improve Procedural Efficiency and Maintain Optimal Outcomes Helene Eltchaninoff
4:59 PM Roundtable Discussion With Audience Q&A
5:04 PM Debate: Adjunctive Imaging Before and During TAVR – Selective (Even Frequent) TEE Trumps the Minimalist Approach for Optimal TAVR Outcomes! Rebecca T. Hahn
5:12 PM Debate: Adjunctive Imaging Before and During TAVR – Multislice CT Reigns Supreme as an Invaluable Imaging Modality for TAVR! Jonathon A. Leipsic
5:20 PM Roundtable Discussion With Audience Q&A
5:25 PM TAVR Alternative Access: Balancing Risks and Benefits of Subclavian, Direct Aortic, and Transapical Approaches Mathew Williams
5:33 PM Roundtable Discussion With Audience Q&A
5:36 PM Early Discharge After TAVR: The Vancouver Clinical Pathway, Including the North America 3M Study Danny Dvir
5:44 PM Roundtable Discussion With Audience Q&A
5:47 PM Adjunctive Pharmacotherapy During and After TAVR: BRAVO 3, GALILEO, and Beyond Torsten P. Vahl
5:57 PM Roundtable Discussion With Audience Q&A
Tricuspid and Pulmonic Valve Interventions, Pulmonary Hypertension, and Pulmonary Emboli Accreditation: CME/CNE
Thursday, October 15 2:00 PM - 6:08 PM Room: Moscone West, 3rd Floor, Room 3014 - 3018
Session I. Tricuspid Valve Intervention 2:00 PM - 4:16 PM Moderators: Rebecca T. Hahn, Joachim Schofer Discussants: Hans R. Figulla, James S. Gammie, Ziyad M. Hijazi, Dominique Himbert, Brij Maini, Gidon Yehuda Perlman
2:00 PM Intervention for Tricuspid Regurgitation: What Do the Guidelines Say? (ACC/AHA and ESC/EACTS) Alec S. Vahanian
2:09 PM Surgical Approaches and Outcomes to Tricuspid Regurgitation James S. Gammie
2:18 PM Roundtable Discussion With Audience Q&A
2:29 PM Role of Noninvasive Imaging for Patient Selection and Procedural Guidance for TR Interventions Rebecca T. Hahn
2:40 PM Transcatheter Valve Implantation in the IVC/SVC for Tricuspid Regurgitation Hans R. Figulla
2:51 PM Transcatheter Valve-in-Valve (Tricuspid Position) Ziyad M. Hijazi
3:02 PM Transcatheter Valve-in-Ring (Tricuspid Position) Dominique Himbert
3:13 PM Roundtable Discussion With Audience Q&A
3:24 PM Transcatheter Tricuspid Regurgitation Treatment 1: MitraClip Brij Maini
3:35 PM Transcatheter Tricuspid Regurgitation Treatment 2: Mitralign Rebecca T. Hahn
3:46 PM Transcatheter Tricuspid Regurgitation Treatment 3: Forma Gidon Yehuda Perlman
3:56 PM Transcatheter Tricuspid Regurgitation Treatment 4: 4Tech Alec S. Vahanian
4:06 PM Roundtable Discussion With Audience Q&A
Session II. Pulmonary Valvuloplasty and Replacement 4:16 PM - 5:12 PM Moderators: John P. Cheatham, Lars Sondergaard Discussants: Zahid Amin, Ziyad M. Hijazi, Eric Horlick, Damien P. Kenny, Doff B. McElhinney, Michael J. Mullen
4:16 PM Balloon Pulmonary Valvuloplasty in the Adult Patient Michael J. Mullen
4:23 PM Transcatheter Pulmonary Valve Implantation Eric Horlick
4:33 PM Nightmare Cases of Pulmonary Valve Implantation Zahid Amin 4:41 PM Transcatheter Pulmonary Valve Implantation in Patients With Transannular Patch Ziyad M. Hijazi
4:48 PM Hybrid Interventions on the Pulmonary Outflow Track in the Adult Patient Damien P. Kenny
4:55 PM Endocarditis After Transcatheter Right Heart Valve Replacement Doff B. McElhinney
5:02 PM Roundtable Discussion With Audience Q&A
Session III. Pulmonary Hypertension: Surgical and Interventional Approaches 5:12 PM - 6:08 PM Moderators: Ori Ben-Yehuda, Ehtisham Mahmud Discussants: Thomas K. Jones, Clifford J. Kavinsky
5:12 PM Hemodynamic Assessment in Patients With Pulmonary Artery Hypertension: Operable vs Inoperable? Thomas K. Jones
5:20 PM Surgical Thromboembolectomy: Indications for, Approaches to, and Outcomes of Chronic Thromboembolic Hypertension Ori Ben-Yehuda
5:30 PM Creation of PFO/ASD in Patients With Pulmonary Hypertension: What Is the Correct Size? Clifford J. Kavinsky
5:38 PM Percutaneous Pulmonary Angioplasty in Chronic Pulmonary Embolism Ehtisham Mahmud
5:48 PM Pulmonary Denervation: Current Status Ori Ben-Yehuda
5:58 PM Roundtable Discussion With Audience Q&A
Interventional Innovation, Part 4: Innovative Concepts, Diagnostics, and Therapies II Accreditation: none
Thursday, October 15 8:00 AM - 12:00 PM Room: Moscone West, 2nd Floor, Room 2014 - 2018
Session I. Interventional Pipeline: Early Experimental and Emerging Clinical Data 8:00 AM - 10:30 AM Moderators: Greg L. Kaluza, Joachim Schofer Discussants: Robert M. Bersin, Nabil Dib, Tim A. Fischell, Michael Joner, Aaron V. Kaplan, James R. Margolis, Torsten P. Vahl
8:00 AM Biodegradable Fe/316L Stent Using Cold Spray Technique Olivier F. Bertrand
8:10 AM The Tricuspid Valve Occluder: A Novel Device for Tricuspid Regurgitation Mohammad Qasim Raza
8:20 AM A New Hybrid Biodegradable Stent for Peripheral Artery Disease Interventions Jung-Hee Lee
8:30 AM A Dedicated Over-the-Wire Microcatheter for Pressure Wire Delivery and Continuous IC Infusion of Adenosine Ahmed Elghamaz
8:40 AM Roundtable Discussion With Audience Q&A
8:50 AM Featured Vascular Innovation Technologies 1: The Bell Balloon-Embolic Capture Technology Giora Weisz
8:58 AM Featured Vascular Innovation Technologies 2: The WIRION Embolic Protection System for Carotid Stenting Andrej Schmidt
9:06 AM Featured Vascular Innovation Technologies 3: Novel Nanocarrier Sirolimus-Coated Balloon for Coronary and Peripheral Applications Sameer I. Dani
9:14 AM Featured Vascular Innovation Technologies 4: Rethinking Dissection Repair Post-PTA – “Tack-It” Endovascular Technology William A. Gray
9:22 AM Featured Vascular Innovation Technologies 5: Denervation in Hypertensive Renal Transplantation Patients – Verve’s Disruptive Nonvascular Catheter Option to Nephrectomy Richard R. Heuser
9:30 AM Roundtable Discussion With Audience Q&A
9:40 AM Miscellaneous Emerging Technologies 1: Wireless Cardiac Pacing Technology (EBR Systems) R Hardwin Mead
9:50 AM Miscellaneous Emerging Technologies 2: The Neovasc Reducer System for Refractory Angina Timothy D. Henry
10:00 AM Miscellaneous Emerging Technologies 3: Dynamic Transcatheter Mitral Valve Repair for Patients With End-Stage Functional Mitral Valve Regurgitation Miriam Silaschi 10:10 AM Miscellaneous Emerging Technologies 4: Stent-Based Pulmonary Vein Isolation Approach to Atrial Fibrillation Glenn Van Langenhove
10:20 AM Roundtable Discussion With Audience Q&A
Session II. The Future of Optical Coherence Tomography and Intravascular Imaging 10:30 AM - 12:00 PM Moderators: Gary S. Mintz, Guillermo Tearney Discussants: Takashi Akasaka, Francesco Burzotta, Giulio Guagliumi, Yuji Ikari, Farouc Jaffer, Lorenz Raber, Evelyn S. Regar
10:30 AM OCT Technological Trends 1: Two-Photon Luminescent-OCT Catheter System Marc D. Feldman
10:40 AM OCT Technological Trends 2: Heart-Beat OCT – Micro Motor System Technology Antonius F.W. van der Steen
10:50 AM Roundtable Discussion With Audience Q&A
11:00 AM OCT Imaging Integration and Emerging Applications 1: FD-OCT Imaging and Endothelial Shear Stress Computation Peter H. Stone
11:10 AM OCT Imaging Integration and Emerging Applications 2: Novel Method for Patient- Specific Coronary Tree Reconstruction by Fusion of X-ray Angiography and Optical Coherence Tomography Shengxian Tu
11:20 AM OCT Imaging Integration and Emerging Applications 3: Intravascular Assessment of Arterial Disease Using Compensated Optical Coherence Tomography Nicolas Foin
11:30 AM OCT Imaging Integration and Emerging Applications 4: Coronary Microstructural/Molecular Imaging Using Dual-Modality OCT and Near-Infrared Autofluoresence (NIRAF) Guillermo Tearney
11:40 AM OCT Imaging Integration and Emerging Applications 4: Intravascular Near-Infrared Fluorescence Molecular Imaging (NIRF) Farouc Jaffer
11:50 AM Roundtable Discussion With Audience Q&A
Featured Clinical Research IV: TCT Award-Winning Oral Abstracts Presented to the Editors of Catheterization and Cardiovascular Interventions and EuroIntervention Accreditation: CME/CNE
Thursday, October 15 12:15 PM - 1:55 PM Room: Moscone South, Lower Level, Room 104
TCT Award-Winning Oral Abstracts Presented to the Editors of Catheterization and Cardiovascular Interventions and EuroIntervention 12:15 PM - 1:55 PM Moderators: Steven R. Bailey, Patrick W. Serruys Discussants: Vasim Farooq, Olaf Franzen, Mayra Guerrero, David W.M. Muller, Mathew Williams
12:15 PM TCT 107: The DISCOVER Registry – One-Year Outcomes of a Fully Repositionable and Retrievable Nonmetallic Transcatheter Aortic Valve in a Real-World Population Federico De Marco
12:25 PM Roundtable Discussion With Audience Q&A
12:30 PM TCT 108: Initial Clinical Experience Performing Robotic Percutaneous Coronary Intervention From the Radial Approach Joseph Sheets
12:40 PM Roundtable Discussion With Audience Q&A
12:45 PM TCT 109: Two-Year Outcomes With the Fully Repositionable and Retrievable Lotus Transcatheter Aortic Replacement Valve in 120 High-Risk Surgical Patients With Severe Aortic Stenosis – Results From the REPRISE II CE-Mark Study Ian T. Meredith
12:55 PM Roundtable Discussion With Audience Q&A
1:00 PM TCT 110: Up-to-1-Year Follow-up Results of the Transcatheter Annuloplasty Ring Multicentre Trial Alec S. Vahanian
1:10 PM Roundtable Discussion with Audience Q&A
1:15 PM TCT 111: Impact of Concomitant Mitral Regurgitation Following Transcatheter Aortic Valve Replacement – Insights From the US TVT National Registry Kreton Mavromatis
1:25 PM Roundtable Discussion With Audience Q&A
1:30 PM TCT 112: Prasugrel in Clopidogrel Nonresponders Undergoing Percutaneous Coronary Intervention – The REsponsiveness To CLOpidogrel And StEnt Thrombosis (RECLOSE) 3 Study Renato Valenti
1:40 PM Roundtable Discussion With Audience Q&A
1:45 PM Editors Grading Session, Followed by Top Winner Announcement Moderators: Steven R. Bailey, Patrick W. Serruys Assessing the Severity of Valvular Heart Disease in the Age of Interventions: An ASE-Sponsored Symposium Accreditation: CME/CNE
Thursday, October 15 1:00 PM - 2:00 PM Room: Moscone North, Lower Level, Room 132
Assessing the Severity of Valvular Heart Disease in the Age of Interventions: An ASE-Sponsored Symposium 1:00 PM - 2:00 PM Moderators: Jeroen J. Bax, Paul A. Grayburn Discussants: Rebecca T. Hahn, Philippe Pibarot
1:00 PM Low-Flow, Low-Gradient Aortic Stenosis: How to Diagnosis, and Should We Treat? Philippe Pibarot
1:10 PM Roundtable Discussion With Audience Q&A
1:15 PM What Defines Severe MR Post-AHA/ACC Guidelines? Paul A. Grayburn
1:25 PM Roundtable Discussion With Audience Q&A
1:30 PM Assessing Postdevice Paravalvular Aortic Regurgitation Rebecca T. Hahn
1:40 PM Roundtable Discussion With Audience Q&A
1:45 PM New Noninvasive Methods for Assessing Valvular Heart Disease Jeroen J. Bax
1:55 PM Roundtable Discussion With Audience Q&A
Early Career Development for the New Interventionalist Accreditation: CME
Thursday, October 15 1:00 PM - 2:00 PM Room: Moscone North, Lower Level, Room 125
Early Career Development for the New Interventionalist 1:00 PM - 2:00 PM Moderators: Manish A. Parikh, Sahil A. Parikh Discussants: Suzanne J. Baron, David A. Cox, Manesh R. Patel
1:00 PM Coronary, Peripheral, and Structural Skills: Balancing Expertise With the Need for Multiple Talents Sahil A. Parikh 1:08 PM Roundtable Discussion With Audience Q&A: Will I Ever Be Done Training?
1:15 PM Understanding Quality: What Kind of QI Should I Look for in Practice? Manesh R. Patel
1:23 PM Roundtable Discussion With Audience Q&A: Avoiding "Rookie" Mistakes
1:30 PM Staying Current and Remaing Relevant: Evolving With the Field David A. Cox
1:38 PM Roundtable Discussion With Audience Q&A: Learning New Skills in an Ever-Changing Field
1:45 PM Things to Do in Your First 5 Years to Grow Your Career Manish A. Parikh
1:53 PM Roundtable Discussion With Audience Q&A: What if the First Job Isn't Right for Me?
Focus on Chronic Kidney Disease and Contrast Nephropathy Accreditation: CME/CNE
Thursday, October 15 1:00 PM - 2:00 PM Room: Moscone North, Lower Level, Room 130
Focus on Chronic Kidney Disease and Contrast Nephropathy 1:00 PM - 2:00 PM Moderators: Somjot S. Brar, Richard Solomon Discussants: Carlo Briguori, Germano Di Sciascio, Hitinder S. Gurm, Roxana Mehran
1:00 PM Impact of Contrast Nephropathy on Medical Management After PCI and on Early Outcomes Somjot S. Brar
1:07 PM Roundtable Discussion With Audience Q&A
1:10 PM Contrast Nephropathy Clinical Trial Updates (AVERT, RenalGuard, Preserve, and Others) Roxana Mehran
1:17 PM Roundtable Discussion With Audience Q&A
1:20 PM Convince Me in 5 Minutes or Less That: Sodium Bicarbonate Is Still Relevant and Might Impact Mortality! Richard Solomon
1:25 PM Roundtable Discussion With Audience Q&A
1:30 PM Convince Me in 5 Minutes or Less That: Contrast Nephropathy Risk in TAVR Is Important! Philippe Généreux
1:35 PM Roundtable Discussion With Audience Q&A
1:40 PM Convince Me in 5 Minutes or Less That: Intravenous and Not Oral Hydration Is the Cornerstone for Contrast Nephropathy Prevention! Somjot S. Brar
1:45 PM Roundtable Discussion With Audience Q&A
1:50 PM Case Presentation: A Complex Patient at High Risk for Contrast-Induced Nephropathy Case Presenter: Carlo Briguori
1:55 PM Roundtable Discussion With Audience Q&A
International Debating Chamber, Part 2 (Sponsored by BCIS): Coronary Intervention on Trial Accreditation: CME
Thursday, October 15 1:00 PM - 2:00 PM Room: Moscone North, Lower Level, Room 124
International Debating Chamber, Part 2 (Sponsored by BCIS): Coronary Intervention on Trial 1:00 PM - 2:00 PM Moderators: Andreas Baumbach, Simon Redwood Discussants: Adrian P. Banning, Nick Curzen, Anthony H. Gershlick, Christian M. Spaulding, Nick E. J. West, Mark A. de Belder
1:00 PM Debate 1: All Patients With Out-of-Hospital VF Arrest Without ST-Segment Elevation Should Go Straight to the Cath Lab (Regardless of Mental Status). I'm for the Proposal! Christian M. Spaulding
1:08 PM Debate 1: All Patients With Out-of-Hospital VF Arrest Without ST-Segment Elevation Should Go Straight to the Cath Lab (Regardless of Mental Status). I'm Against the Proposal! Nick Curzen
1:16 PM Barrister Challenges With Audience Q&A
1:28 PM What Say the Audience Jury (Polling Question)?
1:30 PM Debate 2: BVS Is a Revolutionary Breakthrough, Not an Expensive Gimmick. I'm for the Proposal! Nick E. J. West
1:38 PM Debate 2: BVS Is a Revolutionary Breakthrough, Not an Expensive Gimmick. I'm Against the Proposal! Adrian P. Banning
1:46 PM Barrister Challenges With Audience Q&A 1:58 PM What Say the Audience Jury (Polling Question) Poll Moderators: Andreas Baumbach, Simon Redwood
Revascularization Decisions in the Diabetic Patient Accreditation: CME/CNE
Thursday, October 15 1:00 PM - 2:00 PM Room: Moscone North, Lower Level, Room 131
Revascularization Decisions in the Diabetic Patient 1:00 PM - 2:00 PM Moderators: Frederick Feit, David J. Maron Discussants: Sripal Bangalore, Michael E. Farkouh, Upendra Kaul, Norman E. Lepor, Jennifer A. Tremmel
1:00 PM Pros and Cons of CABG vs PCI in the Diabetic Patient With Multivessel Disease: Insights From Randomized Trials Michael E. Farkouh
1:10 PM Do Contemporary DES Change the Equation for PCI vs CABG in the Diabetic Patient? Sripal Bangalore
1:20 PM Roundtable Discussion With Audience Q&A
1:28 PM Optimal Pharmacology in the Diabetic: What's Here? What's New? What's in the Pipeline? Norman E. Lepor
1:38 PM Roundtable Discussion With Audience Q&A
1:46 PM Case Introduction: A Patient With Diabetes, MVD, and Multisystem Involvement Case Presenter: Jennifer A. Tremmel
1:49 PM Roundtable Discussion: Options for This Patient
1:57 PM Case Resolution: What We Did (and Long-term Follow-up) – A Patient With Diabetes, MVD, and Multisystem Involvement Case Presenter: Jennifer A. Tremmel
Interventional “Rich Emotional Experiences” (aka Complications) Accreditation: CME/CNE Thursday, October 15 1:00 PM - 2:00 PM Room: Moscone North, Lower Level, Room 122
Interventional “Rich Emotional Experiences” (aka Complications) 1:00 PM - 2:00 PM Moderator: Paul S. Teirstein Discussants: Jeffrey W. Moses, Michael J. Mullen, William W. O'Neill
1:00 PM My Most Unforgettable Coronary Complication for 2015 Case Presenter: Jeffrey W. Moses
1:12 PM Roundtable Discussion With Audience Q&A
1:15 PM How PCI Complications Can Help You With the MOC Requirements Paul S. Teirstein
1:27 PM Roundtable Discussion With Audience Q&A
1:30 PM TMVR: A New Procedure With New Complications William W. O'Neill
1:42 PM Roundtable Discussion With Audience Q&A
1:45 PM My Most Unforgettable Structural Complication for 2015 Case Presenter: Michael J. Mullen
1:57 PM Roundtable Discussion With Audience Q&A
Nuts and Bolts of OCT Imaging Accreditation: CME/CNE
Thursday, October 15 1:00 PM - 2:00 PM Room: Moscone North, Lower Level, Room 123
Nuts and Bolts of OCT Imaging 1:00 PM - 2:00 PM Moderators: Takashi Akasaka, Giulio Guagliumi Discussants: Ziad A. Ali, Marc D. Feldman, Jonathan M. Hill, Junya Shite
1:00 PM Identification and Treatment of High-Risk Lesion(s) in ACS With OCT Guidance Case Presenter: Takashi Kubo
1:08 PM Roundtable Discussion With Audience Q&A
1:12 PM OCT in Severe Calcified Lesions Case Presenter: Shiro Uemura 1:20 PM Roundtable Discussion With Audience Q&A
1:24 PM OCT to Guide Bifurcation PCI Case Presenter: Niels R. Holm
1:32 PM Roundtable Discussion With Audience Q&A
1:36 PM OCT to Solve a PCI Nightmare Takashi Akasaka
1:44 PM Roundtable Discussion With Audience Q&A
1:48 PM Use of OCT to Optimize BRS Implantation Evelyn S. Regar
1:56 PM Roundtable Discussion With Audience Q&A
Paravalvular Leak Closure Accreditation: CME/CNE
Thursday, October 15 1:00 PM - 2:00 PM Room: Moscone North, Lower Level, Room 121
Paravalvular Leak Closure 1:00 PM - 2:00 PM Moderator: Chet Rihal Discussants: Eulogio J. Garcia, Giuseppe Tarantini, Adam Witkowski
1:00 PM Paravalvular Leak Closure: Imaging and Localization Nina C. Wunderlich
1:08 PM Case 1: Mitral Paravalvular Leak Closure – Antegrade Approach Case Presenter: David Hildick-Smith
1:17 PM Case 2: Mitral Paravalvular Leak Closure – Transapical Approach Case Presenter: Chad Kliger
1:26 PM Case 3: Aortic Paravalvular Leak Closure – Surgical Valve Case Presenter: Robert Kumar
1:35 PM Case 4: Aortic Paravalvular Leak Closure – After TAVR Case Presenter: Peter M. Pollak
1:44 PM Case 5: Double the Mechanical Valves, Double the Paravalvular Leaks Case Presenter: Eulogio J. Garcia
1:52 PM Outcomes Following Paravalvular Leak Closure Chet Rihal
The Retrograde Approach to CTO Accreditation: CME/CNE
Thursday, October 15 1:00 PM - 2:00 PM Room: Moscone North, Lower Level, Room 120
The Retrograde Approach to CTO 1:00 PM - 2:00 PM Moderator: Masahiko Ochiai Discussants: Emmanouil S. Brilakis, Paul Knaapen, Etsuo Tsuchikane
1:00 PM When to Consider a Retrograde Approach Masahiko Ochiai
1:10 PM Edited Video Case 1 of Retrograde Approach Case Presenter: Etsuo Tsuchikane
1:30 PM Edited Video Case 2 of Retrograde Approach Case Presenter: Paul Knaapen
1:50 PM Roundtable Discussion With Audience Q&A
Guidewire Design and Selection: A User’s Guide (Sponsored by Cardiovascular Research Foundation) (Supported By Abbott, Boston Scientific Corporation, and Medtronic, Inc.) Accreditation: none
Thursday, October 15 6:30 AM - 8:00 AM Room: Moscone South, Lower Level, Room 104
Check-in and Breakfast 6:30 AM - 7:00 AM
Guidewire Design and Selection: A User’s Guide 7:00 AM - 8:00 AM Chairs: Dimitri Karmpaliotis, Martin B. Leon Facultys: Ajay J. Kirtane, Jeffrey W. Moses, Stéphane Rinfret
7:00 AM Welcome and Introductions Chair: Martin B. Leon
7:05 AM Anatomy and Design of Coronary Guidewires 101: Engineering for the Interventionalist Dimitri Karmpaliotis
7:15 AM Applied Use of Coronary Guidewires: Basic Principles for Wire Manipulation in CTO Lesions Stéphane Rinfret
Case Presentations 7:30 AM - 8:00 AM
7:30 AM CTO Wires: Antegrade and Retrograde Approaches Case Presenter: Jeffrey W. Moses
7:45 AM Hydrophilic and Support Wires Case Presenter: Ajay J. Kirtane
7:55 AM Discussion With Audience Q&A
Meet the Trialists IV Accreditation: CME/CNE
Thursday, October 15 2:15 PM - 3:30 PM Room: Moscone West, 3rd Floor, Room 3000
Meet the Trialists 2:15 PM - 3:30 PM Moderators: John D. Carroll, Ioanna Kosmidou Discussants: Howard C. Herrmann, Melissa Nichols, Murat Sezer
2:15 PM SAPIEN 3: Evaluation of a Balloon-Expandable Transcatheter Aortic Valve in High-Risk and Inoperable Patients With Aortic Stenosis – One-Year Outcomes Howard C. Herrmann
2:20 PM Roundtable Discussion With Audience Q&A
2:30 PM BRAVO 3: A Prospective Randomized Trial of Bivalirudin Versus Heparin in Patients Undergoing Transcatheter Aortic Valve Replacement Thierry Lefevre
2:35 PM Roundtable Discussion With Audience Q&A
2:45 PM PARTNER II Valve-in-Valve Registry: Evaluation of a Balloon-Expandable Transcatheter Aortic Valve in Patients With Failed Bioprosthetic Surgical Aortic Valves Danny Dvir 2:50 PM Roundtable Discussion With Audience Q&A
3:00 PM Evaluation of Initial Surgical Versus Conservative Strategies in Patients With Asymptomatic Severe Aortic Stenosis Tomohiko Taniguchi
3:05 PM Roundtable Discussion With Audience Q&A
3:15 PM RESPECT: A Prospective Randomized Trial of PFO Closure in Patients With Cryptogenic Stroke – Long-term Results John D. Carroll
3:20 PM Roundtable Discussion With Audience Q&A
Interactive Technology Center: Hands on Hearts Accreditation: none
Thursday, October 15 8:00 AM - 2:00 PM Room: Moscone North, Lower Level, Hall D
Hands on Hearts 8:00 AM - 2:00 PM Discussants: Tobias Koppara, Robert Kutys, Elena Ladich, Michelle Olson, Maria E. Romero