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Alcohol Indicators: purpose meaning, measurement and uses in public health

Kevin Shield Ph.D.

Pan American Health Organization Webinar

11 December 2019 and health

SOCIETAL & ALCOHOL CONSUMPTION INDIVIDUAL POLITICAL VULNERABILITY FACTORS Volume Patterns Historical periods of FACTORS (current and lifetime) (current and lifetime) alcohol consumption Development and macro-economic Age and gender profiles

Culture & societal Genetics and familial Value factors

OUTCOMES Public health policies Socio-economic status Alcohol-related Social and economic Other causes of disease incidence harms morbidity

Smoking, diet, and Alcohol availability Alcohol-related Mortality from other other risk modifying and marketing mortality causes factors

2 Alcohol consumption and Sustainable Development Goals

Alcohol causes large global health, social and economic burdens

SDG 3.5: “strengthen prevention and treatment of substance abuse, including narcotic drug abuse and harmful use of alcohol”

Reductions in alcohol consumption will help in achieving the SDG goal of “a reduction of premature mortality from non-communicable diseases by a third by 2030”

3 4 Alcohol-Attributable Global Burden of Disease

5 Alcohol-attributable burden of disease

2016 burden of disease attributable to alcohol consumption • 3.0 million deaths; 5.3% of all deaths globally • 131.6 million DALYs; 5.1% of all DALYs global

Change in the age-adjusted alcohol-attributable burden of disease: 2000 to 2016 • -18.1% for deaths • -14.6% for DALYs

Change in the age-adjusted burden of disease: 2000 to 2016 • -23.7% for deaths • -25·2% for DALYs

6 Effects of Alcohol on Health

7 Diseases and injuries causally related to alcohol consumption

8 9 52.4% of all AA deaths occurred before 60 years of age

10 Main indicators of alcohol consumption

Data from population surveys / imputation

Amount of alcohol Prevalence of current Prevalence of people who Amount of alcohol consumed during heavy drinkers, former drinkers are heavy episodic drinkers consumed by age and sex drinking occasions and lifetime abstainers

Country level alcohol consumption data

Adult per capita consumption of alcohol

Adult p er ca pita consumption Adult p er ca pita consumption Adult per capita consumption of alcohol by tourists and of recorded alcohol of unrecorded alcohol from cross-border shopping

11 Data sources - overview

Data collection recorded WHO survey to FAO and other Industry Other counterparts UN organizations

Data collection tourist collection Data verification UN statistics WHO process via Country statistics countries

Data collection unrecorded Delphi round of Survey of general Studies Other national experts population Modelling overview Alcohol Questions for Surveys A subset of key questions from alcohol surveys

14 Main findings: APC • Between 1990 and 2017, APC decreased from 8.5 L (95% CI 8.3–8.6) to 7.9 L (7.5–8.3) • APC is projected to remain stable with an estimated APC of 7.8 L (95% CI 6.9–8.9) by 2030 – This is contrary to the objectives of: oGlobal Strategy on oWHO’s Global Action Plan for the Prevention and Control of NCDs oThe Sustainable Development Goals

15

Unrecorded alcohol (sources)

Data sources:

(i) A nominal expert group Delphi round was conducted between August 2015 and July 2016 (49 countries)

(ii) WHO expert surveys (189 countries)

(iii) WHO’s STEPwise approach to surveillance (STEPS) surveys starting in 2013 (16 countries) Question Response Skip pattern Q3a. During the past 7 days, did _ Yes If “no,” skip to question 4a you consume any home-brewed alcohol, any alcohol brought over _ No the border/from another country, any alcohol not intended for _ Don’t know drinking, or other untaxed alcohol? Q3b. On average, how many Home-brewed spirits, e.g., standard drinks of those listed did [ _ _ ] you consume during the past 7 Home-brewed or , days? e.g., beer, palm or fruit wine [ _ _ ] Alcohol brought over the border/from another country [ _ _ ] Alcohol not intended for drinking, e.g., alcohol-based medicines, perfumes, after shaves [ _ _ ] Other untaxed alcohol [ _ _ ] Figure. World map of the percentage (%) of unrecorded alcohol consumption to total per capita alcohol consumption in 2015 Democratic Republic of the Congo Kenya South Africa Cameroon Zambia

R Nigeria F

A Ghana United Republic of Tanzania Rwanda Chad Côte d'Ivoire Ethiopia Mexico Bolivia

Peru R

M Colombia A Brazil United States of America Guatemala

M Pakistan E Estonia Sweden Latvia Lithuania

Poland R

U Russian Federation E Ukraine Republic of Moldova Belarus Romania Italy Thailand

R India

A E

S Bangladesh Nepal Japan Cambodia

R Republic of Korea P

W Philippines Viet Nam China 0 10 20 30 40 50 60 70 80 90 100 Proportion of total unrecorded (%)

Home produced Brought over border Illegal production Surrogate Other Figure. Sources of unrecorded alcohol in 2015 for selected countries Drinking status Question Response Skip pattern Q1a. Have you ever _ Yes If “no,” skip to Q7 consumed any alcohol such as beer, wine, spirits, _ No or [add other local examples]? _ Don’t know Q1b. Have you consumed _ Yes If “yes,” skip to Q2 any alcohol within the past If “no,” go to Q1c (if 12 months? _ No Q1c is not included, skip to Q7) _ Don’t know

22 Former drinking

Question Response Skip pattern Q1c. Have you stopped _ Yes After answering this drinking due to health question, skip to Q7 reasons, such as a negative _ No impact on your health, or on the advice of your doctor or _ Don’t know other health worker?

23 Alcohol volume

Question Response Skip pattern Q2a. During the past 30 days, Number [ _ _ ] If “0,” skip to Q4a on how many occasions did you have at least one standard ? Q2b. During the past 30 days, Number [ _ _ ] when you drank alcohol, how many standard drinks on average did you have during one drinking occasion?

24 Heavy episodic drinking

Question Response Skip pattern Q4a. How often do you have _ Never If “never,” skip to Q5a six or more drinks per occasion _ Less than monthly _ Monthly _ Weekly _ Daily or almost daily

_ Don’t know

Q4b. During the past 30 days, [ _ _ ] Number of times how many times did you have six or more standard drinks in a single drinking occasion?

25 Main findings: drinking status The prevalence of lifetime abstention (LA) decreased from 20.2% (95% CI 17.7–22.8) in 1990 to 16.9% (14.6–19.4) in 2017 -A further decrease in the prevalence of LA is expected: 15.3% (95% CI: 12.9-18.2) in 2030.

The prevalence of heavy episodic drinking (HED) increased slightly form 24.3% (95% CI: 22.0-26.6) in 1990 to 25.1% (95% CI 22.6-27.6) in 2017 -A further increase in the prevalence of HED is expected: 26.4% (95% CI 23.7 to 29.1) in 2030.

26 27 Best indicator of harmful alcohol use: APC or HED

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0 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 0 10 20 30 40 50 60 Adult per captia consumption of alcohol Prevalence (%) of HED

Very-high HDI countries High HDI countries

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Figure 1. Comparison in the correlation between adult per capita consumption and age-standardized prevalence heavy episodic drinking (HED) with the age-standardized rate of alcohol-attributable deaths stratified by human development index group

30

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Figure 2. Comparison in the correlation between percent changes in adult per capita consumption and age-standardized prevalence heavy episodic drinking (HED) with the age-standardized rate of alcohol- attributable deaths from 2010 to 2016 stratified by human development index group

31 Standard drink of alcohol

32 Why use a standard drink?

The amount of alcohol in a standard drink us useful to define for:

• Economics • UK Weights and Measures Act (1963, 1985, 2001)

• Low-risk drinking guidelines (originally dietary

• Studies measuring alcohol consumption

33 A standard drink in the United States

First appeared in the 1985 US Dietary guidelines

A standard drink is any drink that contains about specified amount of pure alcohol

https://pubs.niaaa.nih.gov/publications/practitioner/PocketGuide/pocket_guide2.htm

34 35 36 The STEPS manual

37 Labelling

38 Drinkers’ knowledge of what a standard drink

Drinkers underestimate the alcohol content of beverages based on %ABV – Australia (Stockwell et al., 1991)

Beer is the most standardized and easiest to report -Sold in single serve containers -Variations in strength and container size -A single poor would lead to over-pouring of stronger brands (Kerr et al., 2012)

For wine and spirits there is a tendency to over pour drinks -Generally poor awareness of wine volume pours (Devos-Comby et al., 2006) -Historically increased serving size and strength for wine (Britton et al., 2016) -Over pouring dependent on size and shape of vessel

39 Measuring Alcohol Use Disorders

Multiple definitions of Alcohol Use Disorders: -DSM–III–R, DSM–IV, DSM 5, and ICD–10 Multiple diagnostic instruments -Composite International Diagnostic Interview (CIDI) -Alcohol Use Disorder and Associated Disabilities Interview Schedule (AUDADIS) -Schedules for Clinical Assessment in Neuropsychiatry (SCAN) -Semi–Structured Assessment for the Genetics of (SSAGA) -Hazardous drinking identification: AUDIT, ASSIST, CAGE, MAST, SSAGA 40 Using the AUDIT as an indicator of Alcohol Use Disorders

41 42 Lange et al., 2019 Figure 2. Relationship between the AUDIT cut‐point and the sensitivity and specificity of the AUDIT in identifying AUDs, by sex, assuming a standard drink size of 10 g of EtOH.

43 Lange et al., 2019 Figure. Screening statistics, by country, for AUDs per 1,000 men screened using the AUDIT cut‐point that provides a specificity of 0.95

44 Lange et al., 2019 Very high risk level of alcohol consumption Rehm et al., 2018 47 Rehm et al., 2018 Alcohol and Socioeconomic Status

48 Probst et al., 2014 Alcohol and smoking

49 Cao et al., 2016 Treatment coverage

50 Question Response Skip pattern Q6a. Did you seek any form of _ No If “no,” skip to question 7. treatment for your use of alcohol _ Yes at any time in the past 12 months?

Q6b. From whom did you receive _ Specialist doctor: Psychiatrist professional treatment? _ Specialist other: Other mental health professional, e.g., psychologist/ counselor/mental health nurse _ Generalist doctor: Any other medical doctor _ Generalist other: e.g., General social worker, community health worker, nurse _ Religious or spiritual advisor _ Traditional healer, herbalist, or spiritualist _ Other

51 Second-hand harms due to alcohol

52 Question Response Skip pattern Q7. In the past 12 _ verbally abused months, have you been _ physically abused negatively impacted _ threatened because of another _ involved in a traffic person’s drinking? accident _ felt unsafe while in a public place _ had unwanted sexual attention, or were pressured into sexual activity _ had your house, car, or property damaged

53 Acknowledgments

WHO, PAHO and Regional Offices CAMH • Vladimir B. Poznyak Ashley Wettlaufer • Dag Rekve Jürgen Rehm • Alexandra Fleischmann Margaret Rylatt • Maristela Monteiro Michael Roerecke • Katia de Pinho Campos Jakob Manthey Charlotte Probst

54 Thank You