Tilray: Global Leader
Total Page:16
File Type:pdf, Size:1020Kb
Tilray: Global Leader What Is Medical Cannabis? Medical cannabis is produced using the flowers of the cannabis plant. Cannabis contains over a hundred different types of cannabinoids, two of the most dominant and common are THC and CBD. Depending on how cannabis plants are cultivated and processed, cannabis products can have a range of potencies of THC and CBD. Patients use medical cannabis to treat or alleviate symptoms for a number of conditions. THC: Some of the reported pharmacodynamic effects of THC-dominant medical cannabis include: Analgesic, muscle relaxant, anti-emetic, appetite stimulating, psychoactive effects, Immunomodulant, anti-seizure, anti-inflammatory and more. CBD: The reported pharmacodynamic effects of CBD-dominant medical cannabis include: Analgesic, muscle relaxant, anxiolytic, neuroprotective, anti- oxidant, anti-psychotic activity, anti-seizure, anti-inflammatory and more. Precisely-Formulated Products Tilray is working closely with patients, physicians, and regulators to provide consistent availability of a range of pharmaceutical-grade medical cannabis products, in accordance with regulations where we operate. We believe patients choose Tilray because we are a scientifically rigorous brand known for producing pure, precise and predictable medical-grade products. We take a scientific approach to product development. Our product line focuses on active ingredients and standardized, well-defined preparations. We use formulations and delivery formats that are intended to allow for consistent and measured dosing, and we test all our products for potency and purity. • Whole flower cannabis: Tilray cultivates more than 50 strains to meet patient needs in THC-dominant, CBD-dominant or balanced varieties. • Ground flower cannabis: Milled cannabis in THC-dominant, CBD-dominant or balanced varities. • Full-Spectrum Oil: Tilray Oils are produced in THC-dominant, CBD-dominant or balanced varieties. The oil can be used in a dropper or taken as a capsule. • Purified Oils: Tilray Purified Oils and capsules undergo a state-of-the-art cold extraction process designed to preserve cannabinoid and terpene content, delivering a pure, aromatic and effective pharmaceutical-grade product. • Clinical Compounds: Tilray is proud to partner with world-leading hospitals and universities to develop and produce precisely crafted study drugs to study the efficacy of medical cannabis for a variety of conditions. We work with established pharmaceutical distributors and pharmacy suppliers to sell our products around the world. 1 Advancing Cannabinoid Science and Fostering Mainstream Acceptance State-Of-The-Art Production Process Tilray choreographs a complex series of cutting-edge processes to deliver unparalleled product to its patients. From cultivation to shipping, Tilray’s team brings precision, professionalism and care to each stage of the process. Advancing Clinical Research Tilray is committed to advancing scientific understanding of the therapeutic potential and risks of cannabinoid-based medicines by collaborating with researchers to conduct clinical trials at world-renowned hospitals and universities. Tilray has supported ten different clinical trials to-date: 1. University of Sydney, NSW Government, Chris O’Brien Lifehouse Testing the efficacy and tolerability of medical cannabis as treatment for chemotherapy induced nausea & vomiting. 2. The Hospital for Sick Children, Toronto, Canada Testing the efficacy and tolerability of medical cannabis oil as treatment for pediatric epilepsy/dravet syndrome. 3. University of British Columbia, Canada Testing medical cannabis as treatment for post-traumatic stress disorder. 4. Grupo Español de Investigación en Neuroocología GEINO, Spain Testing medical cannabis to treat glioblastoma. 5. UCSD, San Diego, USA Testing the efficacy and tolerability of medical cannabis (capsule) as treatment for Essential Tremor. 6. Murdoch Children’s Research Institute, Melbourne, Australia Evaluating the feasibility and acceptability of a randomized placebo- controlled trial of the efficacy of cannabidiol (CBD) in reducing Severe Behavioral Problems in children with intellectual Disabilities. 7. McGill University Health Centre Testing medical cannabis on immune activation in people living with HIV. 8. NYU School of Medicine Trial testing CBD treatment for patients suffering from Alcohol Use Disorder. 9. NYU School of Medicine Trial testing CBD treatment for patients suffering from AUD comorbid with Post-Traumatic Stress Disorder (PTSD). 10. Columbia University First-of-its-kind trial testing the efficacy of cannabis as a treatment for taxane-induced peripheral neuropathy, which affects 67% of women undergoing breast cancer treatment. 2 Leading, Legitimizing and Defining the Future of Cannabis We Are A Global Pioneer We have supplied high-quality medical cannabis products to tens of thousands of patients in fourteen countries spanning five continents across the globe through our subsidiaries in Australia, Canada, Germany and Latin America, and through agreements with established pharmaceutical distributors. Tilray was founded in 2013 with the belief that patients and consumers should have safe access and a reliable supply of quality- tested pure, precise and predictable cannabis products. We aspire to lead, legitimize and define the future of our industry by building the world’s most trusted and valued cannabis company. We are pioneering the future of medical cannabis research, cultivation, processing and distribution globally. Tilray’s EU campus in Cantanhede serves as a hub to support Tilray’s clinical research, product developments and distribution across Europe and other international markets. What Sets Us Apart: • Among the first companies to be licensed by Health Canada to cultivate and sell cannabis in Canada. • The first company to legally export medical cannabis from North America to four continents. • The first cannabis company to successfully complete an Initial Public Offering (IPO) on a major U.S. stock exchange. • Among the first company to cultivate in two countries – Portugal and Canada. • Our Tilray Nanaimo, Canada and Cantanhede, Portugal facilities are Good Manufacturing Practices (GMP) certified. GMP is an internationally recognized standard that ensures medicines are consistently produced and controlled with the highest levels of pharmaceutical grade quality and purity. GMP-certified has allowed us to export our products all over the world. through our subsidiaries in Australia, Canada, Germany and Latin America, and through agreements with established pharmaceutical distributors. 3 International Expansion Seizing Global Opportunities Tilray Portugal In July 2017, the Portuguese National Authority of Medicines and Health Products (IN-FARMED) awarded Tilray a license to cultivate, import and export bulk medical cannabis. Tilray received its first phase of Good Manufacturing Practices certification in August 2019 and approval for manufacturing license GMP certification in December 2019, which allows us to manufacture and distribute finished medical cannabis products throughout the EU and other international markets. The EU requires adherence to GMP standards for the manufacture of active substances and medicinal products, including cannabis products. Tilray has established sales and distribution arrangements to distribute GMP- produced medical cannabis through major pharmaceutical distribution channels throughout Germany and the European Union. Tilray has also formed a global alliance with Sandoz AG, a worldwide leader in generic pharmaceuticals and biosimilars and a part of Novartis group, to increase availability of high quality medical cannabis products around the world in jurisdictions where regulations permit. Tilray Portugal: By The Numbers • 2.5mSQFT multi-faceted production facility that includes outdoor and greenhouse cultivation sites, research labs, processing, packaging and distribution sites for medical cannabis and cannabinoid-derived medical products. • Over 200 employees. This number is expected to grow in 2020. • €20m invested in the build-out of our operations at our EU campus to-date. 4.