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Ingredients for Product Handbook and Catalog for 2018

HEALTH • NUTRITION • MATERIALS Table of Contents DSM I Bright Science. Brighter Living.™...... 2 DSM Nutritional Products...... 4 Innovation Starts with an Idea...... 6 History of DSM...... 8 Nutritional Ingredient Production...... 10 Premixes and Blending...... 12 Nutritional Ingredients...... 14 Knowing Pet Product Technologies...... 16 Knowing Form Technologies...... 18 Pet Nutritional Solutions...... 20 Table of Products...... 23 DSM – Bright Science. Brighter Living.TM Key Sustainability Focus Areas: • Nutrition • Climate Change and Renewable Energy Securing Sustainable • Circular and Bio-Based Economy Operations Operation Aspirations Long-Term Goals

Our Company Our Core Value • Leading in reporting Gold Class DJSI benchmarks Royal DSM N.V. is a global science-based Our mission is supported by our core value: 40 - 45 % company active in , nutrition and materials. Sustainability. Everything we do should contribute • GHG efficiency improvements (2008 - 2025) By connecting its unique competencies in Life to a more sustainable world. To us, achieving Sustainability as > 10 % Sciences and Materials Sciences DSM is driving sustainability means simultaneously pursuing • Energy efficiency Business Growth Driver improvements (2016 - 2025) economic prosperity, environmental progress and economic performance, environmental quality and social advances to create sustainable value for social responsibility. In other words, we strive to Brighter Living Solutions: Eco+ and People+ • Purchased electricity 50 % by 2025 from renewables all stakeholders simultaneously. DSM delivers create value on the three dimensions of People, • Profitable Solutions Better for People innovative solutions that nourish, protect and improve Planet and Profit simultaneously. • Employee engagement 75 % by 2020 and Planet favorable score performance in global markets such as and • Aspiration: 65 % of DSM Products by 2020 dietary supplements, personal care, feed, Sustainability as a DSM Strategy • Safety: Frequency .25 by 2020 recordable index pharmaceuticals, medical devices, automotive, DSM is aiming to improve peoples’ lives and paints, electrical and electronics, life protection, environmental impact, through the way we take alternative energy and bio-based materials. care of our people and own operations, and how Our Brighter Living Solutions are measurably better scarce resources by creating renewables. In order to DSM’s 20,750 employees deliver annual sales we translate this into products and innovations. for the planet (Eco+) and people (People+). This reduce the demand from our economy on nature’s of €7.7 billion. The company is listed on NYSE strategy is aimed at driving profitable growth through limited resources, DSM is committed to extending Euronext. More information can be found at The world has joined forces in 2015 by defining science-based, sustainable solutions addressing the the lifetime of materials and products, and leveraging www.dsm.com. 17 common Sustainable Development Goals (SDGs), global societal issues of our time. Taking an example partnerships. adopted by the United Nations. The SDGs cover a from our animal nutrition and health business, new Who We Are 15 year time frame to 2030 and include 169 targets. ingredients from our CleanCow™ dairy industry With the large societal issues in mind, we have Who we are as a company is the result of strategic DSM contributes to all goals but particularly focusses initiative demonstrated a 30% plus reduction in identified different and distinct levers that drive our choices that we have made. These in turn are based on the following SDGs: SDG 2: No Hunger, SDG 3: methane emissions and increases milk production, product innovation. These levers, help developers on our mission and our core value; they define what Good Health, SDG 7: Renewable Energy/ SDG 13: with no negative impact on animal welfare. We also and marketers to understand how a measurably we believe in and how we go about our business. Climate Action and SDG 12: Responsible strive for 65% of our products to have a measurably better impact can be made for planet and people. Consumption and Production. better impact on planet or people than competitors, The different drivers can all be substantiated with life Our Brand Promise based on standardised sustainability metrics. cycle assessments that address the environmental and social impacts of products impacts along their Bright Science. Brighter LivingTM. This sums up DSM’s Sustainability strategy is rooted in securing life cycle. The drivers are also used to review our who we are, what we stand for and what we aim to safe and sustainable operations, and an engaged innovations under development. By doing so we want achieve. These four words are the shorthand for our workforce. Within our sites and factories we aim for to steer our full portfolio of products and innovations mission, our beliefs and our behaviors – a promise More about DSM’s contribution to the Sustainable substantial greenhouse gas (GHG) emmisions and towards the best positive impact on society. that we make to the world in which we operate. Development goals: https://www.dsm.com/corporate/ energy improvement, and we aim to reach more Bright Science refers to the unique way in which sustainability/managing-sustainability/the-global- renewable electricity and high employee safety With our Brighter Living Solutions, Eco+ and People+ we combine Life Sciences and Materials Sciences goals.html and engagement. This is exemplified in our Dalry we provide products and innovations that are disciplines, technologies and talents. We partner with Scotland C production facility where the measurably better for people and planet. customers and other stakeholders – then we share Society is faced with challenges, and business has cradle to gate footprint of our product is lower than ideas, insights and inspiration to create innovative an increasingly important responsibility to contribute competing products. The smaller environmental foot- and sustainable solutions that address the key by addressing these societal challenges. print is possible because of superior emission control challenges facing society today. Brighter Living refers By anticipating the global trends and societal issues and waste water management, and an efficient heat to our commitment to creating products and solutions with its portfolio of products and services, DSM wants and power station that exports electricity to the grid that make a positive difference to people’s lives. We to create positive societal impact and further develop and receives credits for avoided electricity from other are constantly seeking new ways to improve quality a sustainable business. sources. DSM is building on strong foundations to of life, and we seek to make a positive contribution to Our key sustainable focus areas: ‘Nutrition’, ‘Climate secure our position as a sustainable company. the lives of people today and generations to come. change & renewable energy’ and ‘Circular and Our Mission bio-based economy’ create the right market context Apart from its focus on action to mitigate climate in which DSM’s solutions can flourish. Sustainability change, DSM recognizes resource scarcity as an Our purpose is to create brighter lives for people then becomes a business growth driver and defines important societal issue. To secure future availability today and generations to come. We connect our operational aspirations. of natural resources, we need to apply principles of unique competences in Life Science and Materials careful resource management and unlock more value Sciences to create solutions that nourish, protect With Sustainability as a Business Growth Driver at from the limited resources that are available. DSM and improve performance. DSM, we offer our customers sustainable and has the opportunity to mitigate resource scarcity with scalable solutions, integrating sustainability benefits solutions that prevent of food waste, including food in our value propositions and customer engagement. preservation, increasing the durability of materials, 2 enabling re-use of materials and reducing the use of 3 The DSM quality and safety program is designed mindset is integrated into our ideation DSM Nutritional Products around food safety standards and managed by and innovation workstreams. a worldwide team of qualified quality and safety managers passionate about food safety. These The process of manufacturing bioactive micro experts are responsible for administrating our quality and microorganisms, and blends of and safety program, which includes as the central these micro ingredients, is complex from a quality element the Hazard Analysis of Critical Control Points assurance perspective. We sell these micro Representing the Life Sciences competency DSM Nutritional Products, Animal (HACCP), which follows World Health Organization ingredients to producers of retail products covering of Royal DSM N.V., DSM Nutritional Products Nutritional & Health, Approach to standards and comprises sanitation standards, pest a broad array of dietary needs, ranging from control systems, and minimizing cross-contamination. concentrated dietary supplements to pet contributes €5,169 million to annual sales in 2016 Quality and Safety and is organized around three market-facing entities: We also know that for this program to be successful designed to deliver 100% of the animal’s nutritional Animal Nutrition & Health, & Health Petfood manufacturers and the suppliers that serve it is important to create a high level of internal needs. Due to this complexity, and the safety and Personal Care. More about DSM Nutritional them are aware that pet food is a very highly awareness around every aspect of safety and quality concerns associated with these types of retail Products: https://www.dsm.com/corporate/about/ regulated industry. Its standards for safety and quality along the entire supply chain, creating a company products, it makes sense that Traceability is business-entities/dsm-nutritional-products.html are equal to, or in some cases, surpass those of the culture that lives out safety and quality behaviors that included as one of our 5 Q values. At DSM, the human food industry in some countries. embrace well-designed SOPs. DSM is dedicated to integrity of our quality systemis constantly checked Animal Nutrition & Health addresses the nutrition standardizing and ensures the integrity our program and trained in mock recall and track & trace exercises additives segment of the feed and pet food markets. From a business perspective, managing safety and across the globe by conducting routine audits of all to provide an assurance of safety and functionality. Human Nutrition & Health largely addresses nutrition quality is about mitigating risk to your product’s brand. DSM facilities by a Corporate Operational Audit team Rapid and accurate notification of a recall to our and functional ingredients segment of the food The owners of a retail brand of pet food or snack (COA). Our facility managers will tell you that they customers is the heartbeat of our emphasis on markets. Personal Care is focusing on the actives that harms a companion animal will experience would rather have our customers audit them than the Traceability – only topped by the constant work to and ingredients in the sun care, skin care and hair a cascade of events detrimental to their business. COA team due to the strict guidelines. prevent these cases. care industries. These events include immediate loss of sales, scrutiny by the regulatory authorities, possible The integrity of our food safety program is the basis The DSM 5 Q values Sharing and Learning help us DSM is the only producer who can supply the lawsuits, and public rejection; events that may be for a Trusted Supply Chain. This starts with vendor stay ahead of the curve. By DSM managing quality complete range of and in the severe enough to destroy the brand. qualification and management processes in line and safety on a global scale, using Compliance ® most suitable forms for all possible animal and with food safety standards. Success is achieved Quality Management (CQM) TrackWise system and human uses. As a leading supplier to this industry, DSM has a further through our supply chain by leveraging our other companywide web-based training tools, every global quality and safety standard for our products, excellence in analytics based on our long history in DSM employee becomes integrated into our global DSM has established leadership positions across all including premix, with the goal of meeting or the chemical and biosciences industries, maintaining quality and safety program. three areas of the ingredients business: feed, food exceeding the expectations of the leading petfood robust and integrated documentation, goods receipt, and personal care. DSM is one of the world’s leading brand owners in the market. Our global quality and warehouse management systems. Having the right quality and safety processes in place producer of vitamins. DSM is working from its strong standard is based upon our 5 Q Values. are mandatory, but at DSM we believe you can only global presence in key value-added ingredients Mindful of the risks to both our customers and the achieve the highest level of risk mitigation if you offered through an international infrastructure and Our 5 Q Values take into consideration: Food Safety, sustainability of our business, perpetual improvement integrate a consciousness of quality and safety reach. Trusted Supply Chain, Closing the Loop, Traceability, of this food safety program is part of our business across all employees and it becomes part of your and Sharing and Learning. strategy, we call Closing the Loop. This means, that company’s culture. DSM is uniquely involved in all three steps of the we not only have the tools in place to do a thorough value chain: the production of pure active ingredients, root cause analysis on deviations, we have the tools Our company recognizes that with their incorporation into sophisticated forms, and the in place for change management, the business growth becoming more Food safety provision of tailored premixes. Being the only fully process and techniques to manage the dependent on offering premium integrated player allows DSM to differentiate itself people side of change. This assures petfoods, and a heightened all the way through the chain. the adoption and the realization of a awareness of food safety among Trusted supply chain change are well in control and the risk consumers, suppliers need to be Managing the interdependencies between active minimized. To ensure we are trustworthy partners oriented towards ingredients, forms and premixes, which have Closing the Loop, our mutual success. DSM strives to earn the title of “Trusted Partner”! important implications for innovation, logistics, Traceability and value delivery, is a core competence of DSM.

Striving to earn the title of “Trusted Partner”! Closing the loop

Sharing and learning

4 5 Innovation Starts with an Idea!

It is not only about the idea, DSM Venturing is an active investor in start-up Seeking ideation from Industry partners companies, which create innovative products and combines the benefits of a mutual attraction it's what you do with it! services in Life Sciences and Materials Sciences to a particular market with often very different Idea Generation, often called "Ideation" is the that contribute to the quality of life. DSM Venturing's perspectives on the approach to solving a creative process of generating, evaluating and mission is to explore emerging markets and problem. Couple this with differences in core communicating new ideas. Within DSM, this takes technologies in order to support DSM's innovation competencies and experience, it is not hard to place in a variety of ways: and growth strategy. envision how this would yield a novel approach.

Innovation Idea Generator: A continuous Besides financial support, we offer start-up At DSM Nutritional Products, ideas from exchange of ideas. Often the "seed" that gets companies access to DSM’s knowledge base, all sources are channeled into what we people to think in new ways. Every DSM employee resources and networks creating a business call the idea box. In this stage of the has access to a simple tool to enter their ideas for relationship based on mutual benefits and shared process, dedicated innovation project consideration. learning. managers review the ideas for alignment with our core competencies, Ideation Workshops: A direct way to brainstorm, To DSM businesses we offer a window to the world scope relative to the markets we collect & evaluate ideas during highly participative of innovations that are taking place in the global serve, and economic feasibility. workshops, or as we call them "play shops" events. start-up community; an inroad to collaborations/ The best candidates for further partnerships/licenses/supply & marketing relations exploration are prioritized and Campaigns, Challenges & Competitions: with start-up companies; and an option to spin in formal projects are created. The Topic-specific focus to solve a specific question or ‘outside’ innovations. project managers build a preliminary problem. A fast way of gathering ideas. business case with minimum impact DSM Venturing is an integral part of DSM’s open to those involved in daily business Coaching & Shaping ideas: A process of innovation approach, focused on teaming up with operation. This clears a rather facilitation to shape the idea by identifying the innovative players all over the world. significant resource management potential value design prototypes, run pilots or issue that often stalls the innovation proof-of-concepts. Customer need plays an important role in the process. ideation process at DSM. We starts by listening Business Service Modeling: We use the to the challenges our customers face and In the project phase, these new Enterprise Design Canvas to combine the their novel ideas that lack commercial ideas will undergo a series of steps powers of Innovation & Business Architecture! solution. Mutual success is often which include proof of concept trials, achieved when both parties view sustainability check, and an ideation within a framework of application-specific evaluation. collaboration. During this phase we often collaborate with key accounts which can shorten the development cycle and provide our customer a first-to-market advantage.

Sustainability Check Ultimately project success leads to commercialization, making the IDEA EVALUATION IDEA BOX R&D APPLICATION COMMERCIALIZATION idea available to the world. DSM Venturing Customer Need Industry Business Proof of Concept Partners Case Development Feasibility Development Collaboration 6 7 The world’s strongest fiber™: Dyneema®, the world’s strongest fiber™ is DSM’s premium brand for Ultra High Molecular Weight PolyEthylene (UHMWPE) fiber, UD, flexible composite, tape and fabric. Dyneema® combines maximum strength with minimum weight. It is 15 times stronger than quality steel and 40% stronger than aramid fiber, both on weight for weight basis. Industries like law enforcement, defense, maritime, offshore, History of DSM medical, sports & leisure, fishing, outdoor, automotive, renewable energy, and personal protective equipment rely on Dyneema® for its lightweight, protective and durable properties. Re-Invention of a Successful Company Industrial biocatalysis: In the early 1970’s DSM implemented the first industrial biocatalytic process. Chiral amino acids are produced using specific enzymes, able to synthesize target enantiomers with exceptional purity. A whole toolbox of enzymes and chemical catalysts is now available for producing chiral ingredients for the pharmaceutical industry.

Clean antibiotics production: In 1996 DSM pioneered the first commercial production of semisynthetic antibiotics based on microbial fermentation instead of chemical 1920 synthesis. Identifying new enzymes and constructing new biosynthetic pathways by modern genetic technologies allowed a dramatic Bituminous quality of coal leads to decrease in the environmental impact of antibiotic production. 1902 diversification into fertilizers, utilizing DSM founded as Netherlands the ammonium from coking gas state owned mining company resulting in production of first “DSM – De Staats Mijnen.” ammonia based fertilizer. Sustainability through enzymes: Mining activities focus on 40 years experience in enzyme application has resulted in a large range of enzymes based solutions. DSM’s global alliance with the Limburg region in the Novozymes (DK) provides a wide range of feed enzymes which, together with enzyme solutions for second generation biofuel and South of the Netherlands. 1940 biogas processes, makes a tremendous impact on a sustainable development of global food production. Construction of Central 1963 Laboratory in Geleen. DSM’s first Steam-cracking High yielding cell culture technology: installation opened. Since 2002 DSM, in collaboration with Crucell (NL), has developed a leading technology for the production of antibodies applying 1950’s human cell lines. The technology allows human cells to be cultivated in high density resulting in an efficient biosynthesis at high quality. DSM is licensing out this technology to its customers and acts as development and manufacturing partner. In response to global decline in coal use and increasing importance of polymers, DSM focuses on providing industrial chemicals and raw materials for synthetic fibers and yarns Bio-based performance materials: based on oil and natural gas. In 2010 DSM started to introduce a series of bio-based resins for the automotive industry, proven to match the high performance and speed of traditional chemical products. EcoPaXX® is composed of more than 50% renewable resources helping the industry to meet 1975 1970’s- sustainability targets. It is used in bodyworks, engine compartments and transparent casings for head lamps. 1989 Dutch Prime Minister 1980’s DSM shares floated at the officially closed the DSM diversifies into 1990’s Dutch stock exchange country's last mine. high performing (today Euronext). plastics and fine DSM moves into chemicals. 2005 products for the food and World’s largest production pharmaceutical industries as plant for opens well as performance materials in Sisseln Switzerland. for the automotive and 2008 electronics sector. New regional headquarter 1996 inaugurated in DSM acquires biotech and fermentation Shanghai (China). company Gist-Brocades, a global leader in yeast, yeast extracts, antibiotic 2003 production and enzymes, broadening DSM acquires Roche's DSM into a life science company. Vitamins and Fine Chemicals Division, forming DSM Nutritional 2006 Products, providing the full range Global premix strategy of fat-soluble and water-soluble initiated to grow the vitamins, carotenoids, long chain global premix network polyunsaturated fatty acids, for high-quality mixes. enzymes and nutra-ceuticals Hoffman-La Roche to the feed, pet food, food, pharmaceutical and 2011 1933 1938 1950 personal care industry. • DSM acquires Martek Biosciences • Rebranding of One DSM Commences industrial Establishment Development of the chemical synthesis of of industrial synthesis of ß-carotene. based on the process production of of Nobel prize winner , B1, Tadeusz Reichstein. B2, E and K. 2014 2012 DSM acquires Ocean • DSM opens the China Animal Nutrition Center in Bazhou, China. Nutrition and Fortitech It is focusing on swine and poultry nutrition and has the capability to 2015 conduct world-class scientific and application research. 2013 • POET-DSM Advanced Biofuels, LLC, a joint venture of Royal DSM and POET, LLC, • Acquisition of Aland, which was founded in 1990 and is one of the leading Vitamin C manufacturers in China. DSM acquires opened the first commercial scale cellulosic ethanol plant in the U.S. In 2014 the company realized net sales of about USD 110 million in vitamin C with around 1,800 employees. Tortuga

• DSM and CVC Capital Partners finalize their partnership, ChemicaInvest, for DSM’s Polymer Intermediates • Royal DSM and JLL Partners create a joint venture, Patheon N.V., and Composite Resins. combining Patheon Inc. with the pharmaceutical assets of DSM. 8 9 Nutritional Ingredient Production Our products are micro ingredients whose functionality is specific and whose impact can be enormous. It is therefore imperative to manufacture, package, store and ship them in accordance with the highest quality standards. Whether provided as straight products in bulk or as premixes tailored to individual Backward integration underpins superior quality standards customer needs, our products always meet the most stringent quality requirements.

We work to a unique global quality standard. This is rooted in the official regulations that give us our license to operate and is supplemented by our owninternal quality systems. Full backward integration DSM Nutritional Products operates nine bulk manufacturing and formulation sites allows us to assure quality at every step of the supply chain. We deliver to our customers via a dedicated across Europe, the , Latin America and China. These sites produce logistics network based on three main distribution centers. These are located in Venlo (NL), Belvidere (USA) the majority of DSM’s nutritional ingredients, which are sold either as straight and Singapore. products or as premixes and vitamin concentrates.

Village Neuf, France Formulations of several Grenzach, vitamins and carotenoids Germany Leon, Spain are produced at Village Dalry, UK Located adjacent to DSM’s Leon site is Neuf which is also the Located in Ayrshire, ® the Rhine in Southern dedicated to the production site for STAY-C Scotland the site is Germany, this site primarily Sisseln, production of natural stable vitamin C forms for involved in the production focuses on the production Switzerland Belvidere, USA carotenoids, such as feed applications. The site of vitamin C and related also includes a premix unit water soluble , Sisseln is the production site Located adjacent to the beta-carotene and Mairinque, Brazil derivatives and also the for food applications and and vitamin C for several carotenoids and Delaware River in New . Formerly Tortuga, this production of Panthenol the DSM Research Center derivatives. In addition vitamins A & E. Other Jersey this is the production DSM site produces a full and Ca-Pantothenate. for animal nutrition. intermediates used in the operations include the purifi- site for arachidonic acid and Nova Scotia, range of organic production of carotenoids cation and formulation of Ω3 formulations of various Canada chelates for use in the are produced. fatty acids, the formulation of vitamins including vitamin E The plant in Mulgrave, animal nutrition and several vitamins for various for food applications. Nova Scotia is dedicated health industry. applications and the custom to fish oil processing and synthesis of pharmaceutical Freeport, USA refinement while the plant intermediates. Sisseln is also Novozymes, Freeport, Texas is in Dartmouth, Nova home to our pilot plant and Denmark Scotia is dedicated to the location of a site development center. Novozymes is DSM’s microencapsulation of specializing in the Feed Enzymes Alliance these oils. production of beta partner for more than carotene and intermediates 10 years, researching, for other carotenoids. producing and formulating a portfolio of enzymes for Kingstree, USA use in the animal nutrition The Kingstree, South and health industry Carolina plant is dedicated across the globe. to the production of nutritional lipids by algal and fungal fermentation. Xinghuo, Naperville, USA China Hydroxy-vitamin D The Xinghuo site is destined for feed located close to applications is Shanghai. It is produced at this specialized in the site near Chicago. formulation of vitamin E for feed applications and also includes a premix production facility for food and feed applications.

10 11 Integrated Supply Chain Europe Premixes and Blending DSM manufactures their own range of Our network of thirteen ROVIMIX® vitamins along with many (13) premix plants across Product services where customers need them other key . DSM therefore Europe, the Middle East, has a unique ability to control the and South Africa allow us origin of many ingredients used within the flexibility needed to a premix. DSM’s integrated vitamin supply and serve production and premix supply chain is customers in the region. Delivering Flexible Why do you need a premix? unrivalled. Precision Nutrition Individually weighing and adding many of the Vendor Control very low inclusion ingredients Strict control of all ingredients used Pet owner and consumer awareness level separately during the pet food production process in premix is essential. Since we are surrounding the health benefits relating to vitamins carries a high risk. Weighment inaccuracies and not restricted to only supplying the North America and minerals, and other functional ingredients is poor distribution of very small amounts of the ingredients that we produce, non- Our four (4) North high, often supporting the ‘reason to believe’ separate micro-ingredients within the final pet food DSM raw materials are sourced from American premix plants important label claims such as supporting immune product could affect its nutritional quality or even suppliers in compliance with our 5 Q assure customers service function and bone and joint health. Consequently, safety at the point of consumption. Premixing micro Values. We understand the importance reliability in the supply of this growing health benefit awareness, has led ingredients together, for incorporation into the pet of selecting and sourcing ingredients premixes across the United to the use of a more diverse list of micronutrients food, treat or supplement macro material mix ensures that will protect brand equity for all in States and Canada. and functional ingredients in pet foods to support the active micronutrient particles are distributed the supply chain. specific dietary label claims. more uniformly throughout the final product. DSM DSM has over 50 years of experience producing premixes are a critical link in the pet food supply Track and Trace premixes for use in animal nutrition products. chain and allow accurate, safe, and homogeneous Traceability is a vital component of pet micronutrient and functional ingredient inclusion Premixes are blends of micronutrient and other food safety. DSM’s sophisticated global Latin America functional ingredients as well as suitable carriers. into pet food products. production, quality, purchasing and raw Our experts work closely with customers to develop material intake systems are linked. DSM DSM premix is produced in most Latin American premixes that deliver the ingredient solutions needed DSM Premix Production sites use a bar coding system which countries with a total of to substantiate functionality claims made on labels, allows ingredients used to be tracked Premixes produced by DSM are backed through thirteen (13) premix ensure accurate addition of these ingredients into through from intake at the premix plant– our global assurance of safety and quality. plants. pet foods, treats and supplements, all with the goal the entire premixing process and finally DSM continuously evaluates its responsibilities of achieving the highest possible food nutritional to delivery to the customer. This means and the implication of our footprint in the feed and quality and safety. In addition to meeting functionality we can rapidly track and trace any pet food supply chain. DSM’s premix production claims, we can often meet non-GMO, organic, ingredient used in any premix, meeting and ingredient supply chain is designed around country of origin and grain free requirements. the prompt response times demanded food standards and our 5 Q values: Food Safety, by our customers should the need arise. We have a global network of over 40 premix plants to Trusted Supply Chain, Closing the Loop, Traceability, China DSM has the fastest ensure that we are close to where our customers are. and Sharing and Learning, discussed at length Analytical Expertise on page 4. expanding network of DSM premixes are formulated and premix plants in China manufactured to meet the highest and serves most areas standards for product quality, safety, of the country from efficacy, and traceability while meeting six (6) sites. strict regulatory requirements. Routinely, 10 Things You Need to Know About Premixes premix quality, plus individual ingredients are checked in our own Approximately 80% of the pet food industry uses laboratories located at the premix sites premixes in the production of their complete and 1. Nutrient form quality and at our global analytical centers. balanced pet food products. A premix is a blend of 2. Nutrient form potency Asia Pacific, micronutrients that are individually added to pet food Oceania in “micro” amounts. Combining these ingredients in a 3. Nutrient form stability Nutritional sufficiency against specification, undesirable residues DSM has premix premix simplifies the weighing process and improves 4. Nutrient form physical characteristics accuracy in mixing and distribution of these micro- and routine micro-biological testing is production capabilities in nutrients throughout the food. But, if you think a 5. Carriers and other adjuncts carried out in accordance with DSM all the major feed/pet food premix is “just a blend,” think again. 6. Mixing equipment and procedure quality requirements, local and global producing and exporting countries in the region 7. Premix formulation and use rate regulation. Regular dispersion tests Based on more than 50 years of experience producing with a total of nine (9) micronutrients and premixes for the animal nutrition are also carried out to check the 8. Quality program plants. and health industries, ask your DSM representative to efficiency and quality of our premix share the facts about The 10 Most Important Things 9. Handling of premixes mixing to ensure we deliver a You Need to Know About Premixes: 10. Pet food process and point of addition homogenous premix to our customers.

12 13 Nutritional Ingredients Nutritional Ingredients A Brief Guide to Vitamins Delivering Healthier

DSM produces an extensive portfolio of nutritional ingredients for use in pet food products and supplements including minerals, vitamins, carotenoids, and long chain polyunsaturated fatty acids. These products deliver a wide range of health benefits to DSM’s portfolio of nutritional ingredients includes: a range of carotenoids used for either all pet species. antioxidant functionality or pigmentation, natural sources of omega-3 fatty acids, and trace minerals; all supporting the health and wellness of pets. Vital for the efficiency of a broad array of functions in the body, the DSM vitamin range contains all the vitamins crucial for healthy, thriving, long-living pets. Carotenoids β-Carotene Canthaxanthin Astaxanthin Necessary for vision, growth, and tissue differentiation. Is important for keeping the skin, eyes, and (ROVIMIX®, CaroCare®) (CAROPHYLL® Red) (CAROPHYLL® Pink) Vitamin A inner linings of the body healthy and resistant to infection. Vitamin A is also needed for the maintenance β-carotene is an important source Canthaxanthin is a that has dual Besides pigmentation, astaxanthin and growth of teeth, nails, hair, bones and glands. of vitamin A, converted into vitamin A functionality in birds and fish, skin/feather is a carotenoid that is recognized as required. The additional health pigmentation and biological antioxidant. as being one of the most powerful Helps the body maintain and utilize the levels of calcium and phosphorus needed to build strong bones promoting effects of β-carotene include As an example of pigmentation, the feathers antioxidants found in nature. Other Vitamin D and teeth. Recent studies have shown additional benefits such as supporting immune health, weight antioxidant functionality protecting cells, of a flamingo can range from pink to red health benefits associated with management, and cancer prevention. tissues, and organs from free radical depending on the amount of canthaxanthin astaxanthin include eye health damage and as a contributor to the in its . The biological functionality as an and immune function support. Vitamin B2, Riboflavin robustness of the pet’s immune system. antioxidant, protecting cells from free radical damage and sparing vitamin E. Vitamin E Helps the body transform proteins, fats, and Helps protect cell membranes, carbohydrates into energy. Helps maintain healthy maintain the immune system, skin and eyes and is also necessary for building prolong the life of red blood and maintaining body tissues. cells, maintain a healthy circulatory system, and improve vitamin A use. Vitamin B3, Nutritional Lipids Important for the health & Niacin proper functioning of body Omega-3 from Algae Omega-3 from Fish Niacin and DHA omega-3 derived by Highly refined and tissues. Is an antioxidant, niacinamide are algal fermentation containing deodorized fish oils neutralizing free radicals. essential for fat docosahexaenoic acid (DHA) containing both synthesis, protein and eicosapentaenoic acid eicosapentaenoic metabolism, and the (EPA), fatty acids that support acid (EPA) and conversion of food docosahexaenoic Essential for the clotting of cardiovascular, eye, to energy. acid (DHA). blood and may help maintain and brain health bone health. (e.g. memory), and Vitamin C, directly reduce cellular Ascorbic Acid inflammation supporting Vitamin B1, Thiamine joint, skin, and coat health. Aids in the production of Helps the body use its major source collagen, which provides support of energy, carbohydrates. Thiamine to muscles, vascular tissues, is also essential for proper muscle bones, & cartilage. Aids the coordination, the maintenance of absorption of and improves teeth peripheral nerve tissue, and for Minerals and and gum health. Is an important water normal growth. soluble antioxidant. Enhances the Trace Elements immune response and plays a Examples of important minerals and trace elements Vitamin B5, Essential for the formation of certain nerve-regulating protective role against Pantothenic Acid substances and hormones. It is also required for cardiovascular disease, (Se) system function, neuro- (Zn) Iron (Fe) metabolism of proteins, fats, and carbohydrates. cataracts, and certain cancers. Selenium is an transmitter synthesis Zinc is involved as a co- Iron is an essential component antioxidant that protects and metabolism, melanin enzyme in many cellular of the oxygen carrying cell membranes. formation for pigmentation enzyme systems and impacts hemoglobin in the red blood Vitamin B6, Vitamin B12, Vitamin B9, Vitamin H, of hair and also has an carbohydrate, lipid, protein cells and intramuscular Pyridoxine Cyanocobalamine Folic Acid Biotin (I) antioxidant function as part and nucleic acid metabolism. myoglobin, helps support Necessary for synthesizing Iodine is essential for proper of super oxide dismutase. Necessary for energy Necessary for the formation Required for the formation of It is crucial for collagen and immune function, and is an fatty acids and breaking thyroid gland function. metabolism, the formation of of DNA and the production of red blood cells, certain body keratin synthesis contributing integral part of many important certain proteins, and the use of proteins, and genetic materials down protein and (Mn) healthy red blood cells. Helps Copper (Cu) Manganese contributes to to skin integrity and coat enzymes systems including amino acids. It also helps the for the cell nucleus. Emerging carbohydrate molecules. maintain the nervous system Copper is involved in energy the formation and quality of quality. It is also needed by those supporting energy nervous system to function science suggests it may play Helps in the maintenance and is essential to maintaining production, connective tissue the bones and joint cartilage the immune system and plays production, DHA synthesis, properly and is essential to a an important role in reducing of the thyroid and adrenal formation, iron metabolism, an important role in and functionality as a mental function. Vitamin B12, while also playing an active healthy immune system and risk of cardiovascular disease, glands, nervous system, along with B6 and folate, is normal red blood cell role in the functioning of the reproduction. cellular antioxidant. heart health. dementia, and certain cancers. reproductive tracts, and skin. essential to heart health. formation, normal nervous mitochondria. 14 15 Knowing Pet Product Technologies Understanding How Different Pet Product Technologies Influence the Application of Nutritional Ingredients

Compressed Tablets Milk and Fatty Liquids Tablets are swallowed, chewed or dissolved to deliver their The pet food market is characterized by a wide functional ingredients. During manufacturing the ingre- variety of different product forms. This occurred High fat (oil) paste and liquid products range dients may be ground and screened to obtain a uniform because ingredient forms were developed to from infant food to lubricants for the gastro-intes- particle size. The final blend experiences pressure and tinal tract to aid mobility and control hairballs. During support changes in formulation, process sheer while forming the tablets. Depending on the packag- manufacturing these types of fatty liquids often experi- ing, the tablets may be exposed to moisture and oxygen. conditions, and packaging. ence high shear during mixing and homogenization, high Some tablets are formulated to effervesce when added to temperatures during sterilization, and unwanted enzyme water subsequently exposing the ingredients to moisture, Specially formulated nutritive and functional Wet Products activity. For this application, nutritive ingredients may changes in pH, and further oxidation for an undefined pe- ingredients are often the key to the successful need to be resistant to UV light, oxidation, sheer, high riod of time. For this application, nutritive ingredients need Wet food styles include loaf (pate) development of foods, treats, and supplement and rapidly changing temperatures, enzyme activity, to be resistant to pressure, shear, oxidation, and possibly and chunk-in gravy foods and treats. products. As a leader in nutritional ingredient display high miscibility and emulsification properties reduction in particle size, changes in pH and moisture. Initially, meat and other ingredients are mixed during manufacturing plus remain shelf stable with or without heat for various periods of time. form development, DSM offers a comprehensive for 3 to 24 months without causing This mixture is either placed in a container, sealed range of ingredients suitable for the full range of sedimentation or other negative and cooked at a high temperature or cooked using manufacturing processes and formulation options product attributes. a steam tunnel, formed into chunks, sealed in a con- tainer with gravy, and cooked again at a high temper- our customers use to create products with distinct ature. For this application, nutritive ingredients need points of differentiation. to be resistant to moisture, oxidation, enzymes, and extreme changes in temperature through- out manufacturing. Finally the finished product color must not be adversely affected plus remain shelf sta- ble for 24 months. Injection Molding This process is used to manufacture treats and chews where appearance, structure and actual product design are major challenges. This process usually involves high temperatures Baked Products with a low sheer and moisture. For this application, nutritive ingredients need to be resistant Food, treat, and flaked products are to high and changing temperatures, and oxidation. The finished product color and hardness manufactured using baking. Initially, dough must not be adversely affected and remain shelf stable for 24 months. is formed exposing the ingredients to moisture and sometimes enzymes. The formed dough is heated to the desired degree of cook and dryness. For this application, nutritive ingredi- ents need to be resistant to heat, moisture, enzymes, and oxidation throughout man- ufacturing plus remain shelf stable for 18–24 months. Extruded Products Extrusion, one of the harshest processing technologies, is used to produce Dry Mixes food and treat products. This process typi- and Powders cally requires ingredients to be exposed to high Dry mixture products range from supple- temperatures, pressure, moisture, sheer, rapid Clear Solutions ments to milk replacers. Dry blends require expansion, and a drying step. For this application, ingredients that can be dispersed readily through- Bottled waters are sometimes used to nutritive ingredients need to be resistant to rapid out the mixture, not prone to particle segregation/ deliver functional ingredients. Unlike other changes in temperature, pressure and mois- separation and are chemically stable. Some are liquid products, formulating while maintain- ture heat, sheer, and oxidation throughout designed to be added to liquids and must be read- ing clarity is the challenge. In addition to the ily soluble or miscible. For this application, nutritive manufacturing plus remain shelf stable attributes associated with manufactured ingredients usually need to be uniform in particle size for 18–24 months. liquid products, nutritive ingredients for this and density, chemically and heat stable, have a low application must not react to other ingre- propensity to create an electrostatic charge, not dients, UV light or oxidation causing a attract moisture plus resist oxidation through loss of nutritive value, coloration manufacturing and storage. The finished or sedimentation. product color must also not be adversely affected.

16 17 Knowing Nutrient Form Technologies Leveraging Nutrient Form Technology to Achieve Your Pet Product Nutrition Goals Production of Ingredient Forms Production: Functional ingredients such as vitamins or carotenoids are produced either Form Requirements by chemical synthesis, by fermentation, by extraction (often from a natural source) or by Bioavailability: a combination of these technologies. The nutrient should have a chemical The pet food sector is becoming increasingly sophisticated Modification: Once the basic functional compound is produced it may be further structure which is fully metabolized with the demand for a wide range of ingredients with processed to develop a more stable chemical form, using processes such as and the product formulation should different matrices, textures, colors, shapes and nutritional crystallization of an organic salt, esterification and phosphorylation. provide protection but release the nutrient upon ingestion. functionality as suppliers look to differentiate their products Formulation: To achieve specific product characteristics the ingredients then undergo a on the retailers’ shelves. formulation process. Such formulation creates highly specified nutrient forms optimally equipped to meet the specifications within a pet food, food or feed product. Stability: The ingredient must remain stable “as is” or in blends and premixes. External Factors Influencing Vitamin Stability Therefore the ingredient must be Formulation Technologies adequately stabilized in a chemical and/or product form which when VITAMIN Temperature Oxygen Humidity Light pH Acid pH Alkaline Crystalline grades Beadlets stored, transported, milled, Nutrient compounds are chemically Matrix (gelatin/carbohydrates Vitamin A In beadlet technology nutrient or vegetable) or mixed, maintains its activity. modified to form organic salt which compounds are emulsified in a Vitamin D3 The product form must be resistant after drying are not further gelatin, starch and glycerin matrix, Vitamin E-Acetate to activity loss due to environmental formulated but used “as is”. with an antioxidant sometimes added Optionally crystalline material can factors such as temperature, Vitamin K3 to increase stability. The emulsion is be coated with ethyl cellulose which moisture, and oxygen. Vitamin B1 then sprayed to form beadlets which slows any possible detrimental Nutrient in crystalline form Vitamin B2 influence of other ingredients are coated with corn starch to absorb Uniformity: Vitamin B6 present in the formula. excess moisture. Moist beadlets are dried to produce the finished beadlet. Maize The particle size and size distribution Vitamin B12 Nutrient starch determines how well the nutrient Micronization of the often oily emulsified with Pantothenic Acid antioxidants isdispersed throughout the finished Adsorbates functional ingredient allows the Nicotinic Acid Suitable carriers such as silica Silicic Acid product, impacting the nutrient production of stable, yet dispersable Biotin particles are prepared for adsorbing beadlets for clear liquids. activity per serving. A uniform product mainly fat soluble nutrients. Cross-linked Folic Acid minimizes the tendency for nutrients Adsorption has the advantage of gelatin Vitamin C Matrix to segregate when mixed and delivering an economically attractive Cross-linked Beadlet (gelatin, glycerin dry form of an intrinsically stable and carbohydrates) transported with other micro- =Stable =Slightly Sensitive to Sensitive =Very Sensitive Additional chemical bonds are ingredients, allows adequate flow nutrient, and results in a free-flowing Nutrient adsorbed introduced to create a hardened through equipment during production powder with good mixability, flow- on silica particle beadlet most commonly referred to and reduces dust formation when ability and dust characteristics. as a cross-linked beadlet. A chemical handled. Product Form Requirements reaction occurs which creates cross- Not Low linked bonds thereby creating a more Adversely Coloration Spray-dried powders Affected by and/or Proper Matrix (lignosulfonate) rigid structure. This technology Consistency in Potency: Heat Moisture Shear Resistant to Enzyme Small Compression Resistant to Solubility or Spray-drying is applied for many provides excellent stability and is Stable Stable Tolerant Oxidation Activity Particle Size Tolerant UV Light Miscibility Calcium silicate/ For reliable dosing of a nutrient in of the water soluble nutrients to used to protect nutrients in high Nutrient Extrusion Maize starch emulsified with production, potency must be enhance stability, handling and temperature applications. antioxidants consistent both particle-to-particle Baking distribution. The nutrient compound and lot-to-lot. The availability of Restoring/Steaming is added into a dextrin solution. The solution is spray dried into a appropriate dilutions supports the Fresh/Frozen accuracy of dosing during production. powder, which offers a variety of Silicic acid Injection Molding advantages including stabilizing Nutrient (silica droplets the nutrients and delivering it in a low aide) Dissolution Behavior: Dry Mixing/Powder Tableting/ digestible matrix. The form of the nutrient dictates its Compression aqueous (water) or non-aqueous High Fat Liquid (fats or oils) solubility or miscibility. Low Fat Liquid/Milk These physical characteristics influ- ence the distribution of the functional Clear Water ingredient in the final pet product, its color, texture and/or shelf life

18 19 Pet Nutritional Solutions Optimum Vitamin Nutrition by DSM DSM Vitamin Supplement Guidelines

The humanization of pets has been the driver behind significant growth of premium and superpremium pet food and snack products across the globe. It is increasingly more difficult for those responsible for brand development to create points of differentiation based on nutritional claims considering regulatory and economic Leveraging the full potential of constraints. Although there are many functional ingredients being marketed to pet food manufacturers, those Is OVN™ more than choosing registered for use in pet foods which allow substantive health claims are rare. vitamins, nutrition that supports the right vitamin levels in my DSM is uniquely positioned to provide nutritional solutions designed to help you make your products a long and healthy life. product formulation? attractive to the health-conscious pet product consumers purchasing premium and superpremium products Why are vitamins important to pets? OVN™ is a DSM solution designed for their furry children. Here are a few reasons why: to provide you with practical help Vitamins are involved in most metabolic functions, as formulating the correct vitamin essential for companion animals as they are for humans. • GLOBAL LEADER IN NUTRIENT MANUFACTURING AND PREMIX supplement pack in alignment with Beginning with the first synthesis of vitamins 100 years ago, we have unparalleled experience Although vitamins play a significant role in the health and your brand and business goals. in the manufacture of a broad array of micronutrients, functional ingredients, and premix to well-being of companion animals, the animal feed industry How is this done? create solutions in the best form for the application. only sets vitamin fortification levels for complete feeds at a minimum amount required to prevent overt clinical • It starts with DSM’s OVN™ • INGREDIENTS AS TOOLS deficiency, without guidance on application specific guidelines used to identify the We leverage our broad portfolio of innovative, high-quality health nutrients and work with considerations (e.g. process and storage loss). amount of vitamin activity you need other leading ingredient manufacturers to create quality solutions. to target in your product at the time The pet industry is beginning to consider vitamin of consumption to meet NRC, • KNOWLEDGE AND EXPERIENCE requirements in the wider context of optimum levels, but the AAFCO, and FEDIAF guidelines on trend remains to only follow evidence based upon limited minimum vitamin requirements plus We combine over 30 years of active engagement in the science of measuring studies of low complexity. Such an approach generally any additional vitamin activity animal and human nutrition and health efficacy with collaborative projects with negates experience or intelligent interpretation or needed to support desired health academic and industry specialists to create robust solutions. extrapolation of aspects of physiological processes claims. • PET INDUSTRY DEDICATED TALENT associated with diseases and comparative nutrition as the evidence based approach tends to only consider “hard” We have a dedicated team of pet industry specialists experienced in pet food • Our experts then select the most manufacturing and marketing to create solutions that are relevant. end points of trials. technologically advanced vitamin ingredient forms designed for the • INVESTED IN STUDYING PET CONSUMER INSIGHTS AROUND THE GLOBE In the context of determining Optimum Vitamin Nutrition for application, in compliance with key companion animals there should be perhaps a subtler set of global regulations and DSM’s quality Ultimately consumer perceptions drive the success of any nutritional solution, which considerations as to what constitutes a positive response to and safety program, and with the is why we invest in studies to help us create solutions that help you be successful. vitamin supplementation. OVN™ is a move to maintaining appropriate overages to account overall animal well-being rather than preventing a clear-cut for losses through the product’s deficiency, which includes functional improvements, like coat manufacturing process and storage condition, outward signs of cognitive function, antioxidant ensuring the correct level of vitamins status or stamina during exercise. This is an important point are consumed by the pet. to recognize in your development of quality pet food. • These experts further formulate and produce a pre-blend or premix of these vitamin ingredients leveraging our knowledge and experience producing pet food premixes, considering many factors including proper dilution for accurate dosing and handling characteristics.

• No solution would be complete without a consumer friendly OVN™ logo as a symbol of the optimum Talk to your DSM representative to learn how we can vitamin nutrition inside your deliver the right solution for your brand. product.

20 21 Table of Products

Carotenoids...... 24 ß-Carotene Canthaxanthin Astaxanthin

Fat Soluble Vitamins...... 24 Vitamin A Vitamin D3 Vitamin E Vitamin K, Menadione

Water Soluble Vitamins...... 25 Vitamin B1, Thiamine Vitamin B2, Riboflavin Vitamin B3, Niacin Vitamin B5, Pantothenate Vitamin B6, Pyridoxine Vitamin B9, Folic acid Vitamin B12, Cobalamine Vitamin H, Biotin Vitamin C, Ascorbic acid

Nutritional Lipids...... 27 Omega-3 fatty acids from algae Omega-3 fatty acids from fish

Minerals...... 28 MICROGRAN®, Mineral Preparations VEVOMIN®, Mineral Chelates

Ingredient forms: Feed grade Food grade

Not all products are available in every country but registration is possible.

Application: Dry: Dry pet food and treats Wet: Wet pet food and treats Injection: Injection molded chews Tablet: Tablet supplements Powder: Powder supplements Milk: Milk and low fat liquid products Water: Water based liquid products

Icons like this provide a general indication the ingredient category is commonly registered for use in diets or supplements for that species.

22 23 Carotenoids Fat Soluble Vitamins (Cont.)

ß-Carotene

Product Package Country Product Country Product Name Product Name Package Size (KG) Description Size (KG) of Origin Description of Origin Dry Wet Injection Tablet Powder Milk Water Dry Wet Injection Tablet Powder Milk Water Tocopheryl Acetate ® Stabilized Beadlet 5, 20 France Clear Viscous Oil 190 Switzerland ROVIMIX β-Carotene 10% • • • • • Technical Grade (100% Basis) • • • ROVIMIX® -Carotene 10% P Cross-Linked Beadlet 20 France 20, 500, 900 Switzerland β • • ROVIMIX® E 50% Adsorbate Vitamin E Oil Adsorbed • • • 20, 25, 700, 900 USA Beadlet, Cold Water (500 IU/gm) on Silicon Dioxide • • • 1, 5, 25 Switzerland 25, 500 China β-Carotene 10% CWS Dispersible • • • • • • • • 20 France ROVIMIX® E 50% SD Spray Dried, Water β-Carotene 10% B Cross-Linked Beadlet 5, 25 Switzerland 25 Switzerland • (500 IU/gm) Dispersible Powder • • • • • 25 USA Dry Vitamin E 50% CWS/S Spray-Dried, Cold 20 France Canthaxanthin (500 IU/g) Water Dispersible 20 Switzerland • • • Dry Vitamin E 50%, Type SD Switzerland Product Package Country Spray-Dried, Powder 15 Product Name (500 IU/g) USA • • • • Description Size (KG) of Origin

Dry Wet Injection Tablet Powder Milk Water Dry Vitamin E 75 HP Beadlet, High Potency 20 USA (750 IU/g) • CAROPHYLL® Red 10% Beadlet 5, 20 France • • • • • dl-α- 70 IP Liquid Antioxidant 5, 20 Switzerland • • Liquid Antioxidant, Astaxanthin Mixed Tocopherols 70 IP Natural Source, 18, 190 Argentina • • • Non-GMO Liquid Antioxidant, Product Package Country Mixed Tocopherols 95 20, 190 USA Product Name Natural Source • • • Description Size (KG) of Origin

Dry Wet Injection Tablet Powder Milk Water Dry Antioxidant, Dry Mixed 30% 20 USA • • • • • • • Beadlet, Cold Water Natural Source CAROPHYLL® Pink 10% CWS 5, 20 France Dispersible • • • • •

Product Package Size Country Product Name Description (KG) of Origin Fat Soluble Vitamins Dry Wet Injection Tablet Powder Milk Water MSBC Turkey (Sodium Bisulfite Complex, 33%) Fine Crystalline Powder 25 Uruguay • • • • • • • Available in USA Only China Turkey ROVIMIX® K3 MNB • • • • • • • Fine Crystalline Powder 25 Uruguay (Menadione Nicotinamide Bisulfite) • • • • • • • China • • • • • • • Product Package Size Country Product Name Description (KG) of Origin Dry Wet Injection Tablet Powder Milk Water ROVIMIX® A 1000 (100 kIU/g) Cross-Linked Beadlet 25 Switzerland • • • ROVIMIX® AD3 1000/200 Cross-Linked Beadlet, 25 Switzerland (1000 kIU A/g) (200 kIU D3/g) Stabilized Beadlet • • • Water Soluble Vitamins ROVIMIX® A 500 WS Spray Dried, Water 20 France (500 kIU/g) Dispersible Beadlet • • • • • Cross-Linked Beadlet, ROVIMIX® A 500 N (500 kIU/g) 25 China No Porcine Gelatin Oily Solution (Peanut Vitamin A Palmitate 1.0 mIU/g Oil), Stabilized with 5 Switzerland • • Tocopherol Product Package Country Product Name Oily Liquid, Stabilized Description Size (KG) of Origin Vitamin A Palmitate 1.7 mIU/g 5, 20, 190 Switzerland with Tocopherol • • Dry Wet Injection Tablet Powder Milk Water Dry Vitamin A Acetate 500 B ROVIMIX® B1 Beadlet, Tablet Grade 5, 20, 25 USA Fine Crystalline Powder 25 Germany (500 kIU/g) • • • • (Thiamine Mononitrate) • • • • • • • Dry Vitamin A Palmitate, Spray-Dried, Thiamine HCI 20 France Fine Crystalline Powder 10 Germany Type 250 S/N (250 kIU/g) Starch Based • • • (Thiamine Hydrochloride) • • • • • Thiamine Mononitrate Powder 20 Germany • • Rocoat® Thiamine 33 1/3% Coated Powder 5 USA • • •

Product Package Size Country Product Name Description (KG) of Origin Dry Wet Injection Tablet Powder Milk Water

Spray-Dried, ROVIMIX® D3 500 (500 kIU/g) Water Dispersible, 20 France Product Package Country • • • • • Product Name Stabilized Powder Description Size (KG) of Origin Dry Wet Injection Tablet Powder Milk Water ROVIMIX® AD3 1000/200 Cross-Linked Beadlet, 25 Switzerland • • • Spray-Dried, Water (1000 kIU A/g), 200 kIU D3/g) Stabilized Beadlet ROVIMIX® B2 80-SD 20 Germany Dispersible Powder • • • • • • • Oily Solution, Vitamin D3 1.0 mIU/g Stabilized with 5 Switzerland • • • • • Riboflavin Tablet Grade Tablet Grade 10 Germany • Tocopherol Riboflavin Universal Powder 10 Germany Spray-Dried, Cold • • • • • Dry Vitamin D3 100 SD/S Water Dispersible, 5, 20 Switzerland Rocoat® Riboflavin 33 1/3% Coated Powder 5 USA (100 kIU D3/g) Stabilized with • • • • • • • • • • Tocopherol 24 25 Water Soluble Vitamins Water Soluble Vitamins (Cont.)

Product Package Country Product Package Country Product Name Product Name Description Size (KG) of Origin Description Size (KG) of Origin Dry Wet Injection Tablet Powder Milk Water Dry Wet Injection Tablet Powder Milk Water

® ROVIMIX® Stay-C® 35 ROVIMIX Niacin Fine Crystalline Powder 25, 900 Switzerland Spray-Dried Powder, • • • • (Sodium Calcium Ascorbyl 25, 800 France Heat Stable • • • • ROVIMIX® Niacinamide Fine Crystalline Powder 20, 900 China • • • • • • • Phosphate) Ethlcellulose-Coated Rocoat® Niacinamide 33 1/3% Coated Powder 5 USA ROVIMIX® C-EC 25 Great Britain • • • Powder • • • Stay-C® 50 Spray-Dried Fine 5, 20 France (Sodium Ascorbyl Phosphate) Powder, Heat Stable • • • • • Ascorbic Acid Crystalline Powder 25 Great Britain • •

Product Package Country Product Name Ascorbic Acid Fine Powder Fine Powder 25 Great Britain Description Size (KG) of Origin • • Dry Wet Injection Tablet Powder Milk Water Ascorbic Acid Fine Granular Fine Granular Powder 25 Great Britain ROVIMIX® CalPan Spray-Dried, Water • • 25 Great Britain (Calcium Pantothenate) Dispersible Powder • • • • • • • Ascorbic Acid 95% Granulation Granular Powder 25 Great Britain Calcium D-Pantothenate Spray-Dried Powder 25 Great Britain • • • • • • • • • Calcium Ascorbate Powder 25 USA • • • •

Calcium Palmitate Powder, Antioxidant 5, 25 Germany • • • • •

Product Package Country Product Name Description Size (KG) of Origin Dry Wet Injection Tablet Powder Milk Water

25 Germany ROVIMIX® B6 Fine Crystalline Powder 25 China • • • • • • 20 Germany Pyridoxine Hydrochloride Crystalline Powder 20 China • • • • • • Nutritional Lipids Rocoat® Pyridoxine Coated Powder 5 USA Hydrochoride 33 1/3% • • •

Product Package Country Product Package Country Product Name Product Name Description Size (KG) of Origin

Description Size (KG) of Origin Dry Wet Injection Tablet Powder Milk Water Dry Wet Injection Tablet Powder Milk Water DHAgold® S-17-B Fine Dry Flakes 15 USA Spray-Dried, Water 20 France Min. 17% DHA of Microalgae • • • ROVIMIX® Folic 80 SD • • • • • • • Dispersible Powder 25 China • • • • • • • DHASCO® Microalgae Derived Oil 9, 18, 200 USA • • • • Folic Acid Powder 1, 25 Switzerland • • • • • • • Min. 40% DHA 60 life’s™OMEGA 1, 5, 23, Min. 30% DHA, 15% EPA Microalgae Derived Oil USA 180 • • • Min. 60% Total Omega-3

® S17-P100 Free-Flowing Powder of life’sDHA 12.5 USA Min. 17% DHA Microalgae Derived Oil • • • • • • Product Package Country Product Name Description Size (KG) of Origin Dry Wet Injection Tablet Powder Milk Water

Crystalline Powder Vitamin B12 1% Feed Grade 20 France Dilution • • • • •

0.01, Product Package Country Vitamin B12 Crystalline Crystalline Powder France Product Name 0.1, 1 • • • • • Description Size (KG) of Origin Crystalline Powder Dry Wet Injection Tablet Powder Milk Water Vitamin B12 0.1% WS 5, 15 Switzerland Dilution • • • • MEG-3® 30% TG Oil Min. EPA + DHA area %, min. 30% Min. EPA + DHA content as Marine Fish Oil 190 Peru T.G. 260 mg/g • • • • Min. EPA + DHA content as F.F.A. 250 mg/g MEG-3® 30% Powder Product Package Country Min. 150mg - Max 220mg Microencapsulated Product Name 10 USA Description Size (KG) of Origin EPA + DHA and 180mg Marine Fish Oil Powder • • • • •

Dry Wet Injection Tablet Powder Milk Water Total Omega-3 per g Spray-Dried, Water ROVIMIX® Biotin (2% Biotin) 20 France Dispersible Powder • • • • • • • ROVIMIX® Biotin HP Spray-Dried, Water France 20 (10% Biotin) Dispersible Powder USA • • • • • • • White Crystaline D-Biotin 0.05, 1, 25 France Powder • • Bitrit-1 Type A (1% Biotin) Triturate, Powder 10, 50 USA • • • • •

26 27 Minerals Notes

Product Package Country Product Name Description Size (KG) of Origin Dry Wet Injection Tablet Powder Milk Water

MICROGRAN® Co 5% BMP Free-Flowing, 25, 500 Italy (Preparation of Carbonate) Micro Granules • • • • • • • MICROGRAN® Se 1% BMP Free-Flowing, 25, 500 Italy (Preparation of Sodium Selenite) Micro Granules • • • • • • • MICROGRAN® Se 4.5% BMP Free-Flowing, 25 Italy (Preparation of Sodium Selenite) Micro Granules • • • • • • • MICROGRAN® I 10% BMP Free-Flowing, 25, 500 Italy (Preparation of Calcium Iodate) Micro Granules • • • • • • •

Product Package Country Product Name Description Size (KG) of Origin Dry Wet Injection Tablet Powder Milk Water

VEVOMIN® Cu 13% (Cupric Chelate of Amino Acids, Free-Flowing Powder 25 Canada • • • • • • • Hydrate) VEVOMIN® Fe 12% (Ferrous Chelate of Amino Acids, Free-Flowing Powder 25 Canada • • • • • • • Hydrate) VEVOMIN® Mn 11% (Manganese Chelate of Amino Free-Flowing Powder 25 Canada • • • • • • • Acids, Hydrate) VEVOMIN® Zn 13% (Zinc Chelate of Amino Acids, Free-Flowing Powder 25 Canada • • • • • • • Hydrate)

28 Contact Us To find out more about our ingredients for pet nutrition, please contact your nearest DSM Nutritional Products office.

Headquarters DSM Nutritional Products AG P.O. Box 2676 4002 Basel Switzerland Email: [email protected] www.dsmnutritionalproducts.com

Area Europe, Middle East and Africa DSM Nutritional Products Europe AG Heanor Gate Industrial Estate Delves Road, Unit 41 Heanor Derbyshire DE75 7SG United Kingdom Phone: + 44 17 7353 6598 Fax: + 44 17 7353 6600 Email: [email protected]

China DSM (China) Limited 118 Baisha Road Xinghuo Development Zone Shanghai 201419 China Phone: + 86 21 5750 4888 Fax: + 86 21 5750 4567 Email: [email protected]

Asia Pacific, Australia DSM Nutritional Products Asia Pacific Pte. Ltd. 41 Edison Rd Wagga Wagga, NSW 2650 Australia Phone: + 61 2 6922 7015 Email: [email protected]

Latin America DSM Nutritional Products Latin America Av. Eng. Billings, 1729-Predio 31 05321-010 São Paulo – SP Brasil Phone: + 55 11 3760 6300 Email: [email protected]

North America DSM Nutritional Products, LLC 45 Waterview Boulevard Parsippany, NJ 07054-1298 United States of America Phone: + 1 973-257-8504 Fax: + 1 973-257-8653 Email: [email protected]

This brochure does not constitute a recommendation or guidance for decisions concerning the purchase, use or application of products and does not relieve the user of the product of the obligation to undertake its own suitability, performance or quality testing. THIS BROCHURE IS PROVIDED ON AN “AS IS” BASIS. ALTHOUGH THE INFORMATION SET FORTH IN THIS BROCHURE IS PRESENTED IN GOOD FAITH AND BELIEVED TO BE CORRECT, DSM NUTRITIONAL PRODUCTS AG AND ITS AFFILIATED COMPANIES (HEREINAFTER “DSM”) MAKES NO REPRESENTATIONS OR WARRANTIES, EITHER EXPRESS OR IMPLIED, OF MERCHANTABILITY, FITNESS FOR A PARTICULAR PURPOSE OR OF ANY OTHER NATURE WITH RESPECT TO INFORMATION OR THE PRODUCTS TO WHICH INFORMATION REFERS. No information set forth in this brochure constitutes a solicitation or offer, or invitation to conclude any legal act of any kind whatsoever. The content of any purchase contract (i.e. technical data, price and applications of the products of DSM) concerning the purchase of DSM products is constituted only by the purchase agreement as such and integral parts thereof (specifications in this brochure never form part of a contract). All trademarks, product names, symbols and graphics appearing in this brochure are the property of DSM unless indicated otherwise. All DSM trademarks are either registered trademarks or trademarks of DSM Group of Companies in the Netherlands and/or other countries. No license to or right in any such trademarks, trade names, trade secrets, products or other proprietary rights of DSM is granted or conferred to any party without a written agreement.

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