DF6216-CSRP1 Antibody

Total Page:16

File Type:pdf, Size:1020Kb

DF6216-CSRP1 Antibody Affinity Biosciences website:www.affbiotech.com order:[email protected] CSRP1 Antibody Cat.#: DF6216 Concn.: 1mg/ml Mol.Wt.: 21kDa Size: 50ul,100ul,200ul Source: Rabbit Clonality: Polyclonal Application: WB 1:500-1:2000, IHC 1:50-1:200, ELISA(peptide) 1:20000-1:40000 *The optimal dilutions should be determined by the end user. Reactivity: Human,Mouse,Rat Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific). Specificity: CSRP1 Antibody detects endogenous levels of total CSRP1. Immunogen: A synthesized peptide derived from human CSRP1, corresponding to a region within the internal amino acids. Uniprot: P21291 Description: This gene encodes a member of the cysteine-rich protein (CSRP) family. This gene family includes a group of LIM domain proteins, which may be involved in regulatory processes important for development and cellular differentiation. The LIM/double zinc-finger motif found in this gene product occurs in proteins with critical functions in gene regulation, cell growth, and somatic differentiation. Alternatively spliced transcript variants have been described. [provided by RefSeq, Aug 2010] Storage Condition and Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM Buffer: NaCl, 0.02% sodium azide and 50% glycerol.Store at -20 °C.Stable for 12 months from date of receipt. Western blot analysis of CSRP1 expression in Mouse lung lysate 1 / 2 Affinity Biosciences website:www.affbiotech.com order:[email protected] DF6216 at 1/100 staining Mouse brain tissue by IHC-P. The sample was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. The sample was then blocked and incubated with the antibody for 1.5 hours at 22°C. An HRP conjugated goat anti-rabbit antibody was used as the secondary antibody. IMPORTANT: For western blot, incubate membrane with diluted primary Ab in 5% w/v milk , 1X TBS, 0.1% Tween®20 at 4°C with gentle shaking, overnight. For Research Use Only. Not for use in diagnostic and therapeutic procedures. Not for resale without express authorization. 2 / 2 Powered by TCPDF (www.tcpdf.org).
Recommended publications
  • Screening and Identification of Hub Genes in Bladder Cancer by Bioinformatics Analysis and KIF11 Is a Potential Prognostic Biomarker
    ONCOLOGY LETTERS 21: 205, 2021 Screening and identification of hub genes in bladder cancer by bioinformatics analysis and KIF11 is a potential prognostic biomarker XIAO‑CONG MO1,2*, ZI‑TONG ZHANG1,3*, MENG‑JIA SONG1,2, ZI‑QI ZHOU1,2, JIAN‑XIONG ZENG1,2, YU‑FEI DU1,2, FENG‑ZE SUN1,2, JIE‑YING YANG1,2, JUN‑YI HE1,2, YUE HUANG1,2, JIAN‑CHUAN XIA1,2 and DE‑SHENG WENG1,2 1State Key Laboratory of Oncology in South China, Collaborative Innovation Centre for Cancer Medicine; 2Department of Biotherapy, Sun Yat‑Sen University Cancer Center; 3Department of Radiation Oncology, Sun Yat‑Sen University Cancer Center, Guangzhou, Guangdong 510060, P.R. China Received July 31, 2020; Accepted December 18, 2020 DOI: 10.3892/ol.2021.12466 Abstract. Bladder cancer (BC) is the ninth most common immunohistochemistry and western blotting. In summary, lethal malignancy worldwide. Great efforts have been devoted KIF11 was significantly upregulated in BC and might act as to clarify the pathogenesis of BC, but the underlying molecular a potential prognostic biomarker. The present identification mechanisms remain unclear. To screen for the genes associated of DEGs and hub genes in BC may provide novel insight for with the progression and carcinogenesis of BC, three datasets investigating the molecular mechanisms of BC. were obtained from the Gene Expression Omnibus. A total of 37 tumor and 16 non‑cancerous samples were analyzed to Introduction identify differentially expressed genes (DEGs). Subsequently, 141 genes were identified, including 55 upregulated and Bladder cancer (BC) is the ninth most common malignancy 86 downregulated genes. The protein‑protein interaction worldwide with substantial morbidity and mortality.
    [Show full text]
  • CRIP1 Antibody (C-Term) Affinity Purified Rabbit Polyclonal Antibody (Pab) Catalog # Ap4707b
    10320 Camino Santa Fe, Suite G San Diego, CA 92121 Tel: 858.875.1900 Fax: 858.622.0609 CRIP1 Antibody (C-term) Affinity Purified Rabbit Polyclonal Antibody (Pab) Catalog # AP4707b Specification CRIP1 Antibody (C-term) - Product Information Application WB, IHC-P, FC,E Primary Accession P50238 Other Accession P63255, P63254, Q56K04 Reactivity Human Predicted Bovine, Mouse, Rat Host Rabbit Clonality Polyclonal Isotype Rabbit Ig Calculated MW 8533 Antigen Region 48-77 CRIP1 Antibody (C-term) - Additional Information Gene ID 1396 All lanes : Anti-CRIP1 Antibody (C-term) at 1:8000 dilution Lane 1: T47D whole cell Other Names lysate Lane 2: THP-1 whole cell lysate Cysteine-rich protein 1, CRP-1, Cysteine-rich Lysates/proteins at 20 µg per lane. heart protein, CRHP, hCRHP, Cysteine-rich Secondary Goat Anti-Rabbit IgG, (H+L), intestinal protein, CRIP, CRIP1, CRIP, CRP1 Peroxidase conjugated at 1/10000 dilution. Predicted band size : 9 kDa Blocking/Dilution Target/Specificity buffer: 5% NFDM/TBST. This CRIP1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 48-77 amino acids from the C-terminal region of human CRIP1. Dilution WB~~1:8000 IHC-P~~1:50~100 FC~~1:10~50 Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity CRIP1 Antibody (C-term) (Cat. #AP4707b) purification. IHC analysis in formalin fixed and paraffin embedded bladder carcinoma followed by Storage peroxidase conjugation of the secondary Maintain refrigerated at 2-8°C for up to 2 antibody and DAB staining.
    [Show full text]
  • Identification of Differentially Expressed Genes in Human Bladder Cancer Through Genome-Wide Gene Expression Profiling
    521-531 24/7/06 18:28 Page 521 ONCOLOGY REPORTS 16: 521-531, 2006 521 Identification of differentially expressed genes in human bladder cancer through genome-wide gene expression profiling KAZUMORI KAWAKAMI1,3, HIDEKI ENOKIDA1, TOKUSHI TACHIWADA1, TAKENARI GOTANDA1, KENGO TSUNEYOSHI1, HIROYUKI KUBO1, KENRYU NISHIYAMA1, MASAKI TAKIGUCHI2, MASAYUKI NAKAGAWA1 and NAOHIKO SEKI3 1Department of Urology, Graduate School of Medical and Dental Sciences, Kagoshima University, 8-35-1 Sakuragaoka, Kagoshima 890-8520; Departments of 2Biochemistry and Genetics, and 3Functional Genomics, Graduate School of Medicine, Chiba University, 1-8-1 Inohana, Chuo-ku, Chiba 260-8670, Japan Received February 15, 2006; Accepted April 27, 2006 Abstract. Large-scale gene expression profiling is an effective CKS2 gene not only as a potential biomarker for diagnosing, strategy for understanding the progression of bladder cancer but also for staging human BC. This is the first report (BC). The aim of this study was to identify genes that are demonstrating that CKS2 expression is strongly correlated expressed differently in the course of BC progression and to with the progression of human BC. establish new biomarkers for BC. Specimens from 21 patients with pathologically confirmed superficial (n=10) or Introduction invasive (n=11) BC and 4 normal bladder samples were studied; samples from 14 of the 21 BC samples were subjected Bladder cancer (BC) is among the 5 most common to microarray analysis. The validity of the microarray results malignancies worldwide, and the 2nd most common tumor of was verified by real-time RT-PCR. Of the 136 up-regulated the genitourinary tract and the 2nd most common cause of genes we detected, 21 were present in all 14 BCs examined death in patients with cancer of the urinary tract (1-7).
    [Show full text]
  • A Sonic Hedgehog Signaling Domain in the Arterial Adventitia Supports Resident Sca1؉ Smooth Muscle Progenitor Cells
    A sonic hedgehog signaling domain in the arterial adventitia supports resident Sca1؉ smooth muscle progenitor cells Jenna N. Passman*†, Xiu Rong Dong*‡, San-Pin Wu*§, Colin T. Maguire*‡, Kelly A. Hogan¶, Victoria L. Bautch*†¶, and Mark W. Majesky*†‡ʈ** *Carolina Cardiovascular Biology Center, Departments of ‡Medicine, ʈGenetics, and ¶Biology, and †Curriculum in Genetics and Molecular Biology, University of North Carolina, Chapel Hill, NC 27599 Edited by Eric N. Olson, University of Texas Southwestern Medical Center, Dallas, TX, and approved April 22, 2008 (received for review December 6, 2007) We characterize a sonic hedgehog (Shh) signaling domain re- interstitial fibroblasts (13, 14), and promotes endothelial cell stricted to the adventitial layer of artery wall that supports resi- chemotaxis and tube formation (17, 18). Therefore, Shh plays dent Sca1-positive vascular progenitor cells (AdvSca1). Using important roles in cell–cell communication during vascular patched-1 (Ptc1lacZ) and patched-2 (Ptc2lacZ) reporter mice, adven- development and adult wound repair. titial Shh signaling activity was first detected at embryonic day (E) Hedgehog (Hh) proteins signal by binding to patched-1 (Ptc1) 15.5, reached the highest levels between postnatal day 1 (P1) and or patched-2 (Ptc2) receptors and cdo/boc accessory proteins at P10, was diminished in adult vessels, and colocalized with a the cell surface, resulting in derepression of smoothened (smo) circumferential ring of Shh protein deposited between the media (19). Ptc proteins are 12-transmembrane domain receptors that ؊/؊ and adventitia. In Shh mice, AdvSca1 cells normally found at the are structurally related to the resistance-nodulation-division aortic root were either absent or greatly diminished in number.
    [Show full text]
  • BMC Developmental Biology Biomed Central
    BMC Developmental Biology BioMed Central Research article Open Access Targeted disruption of the mouse Csrp2 gene encoding the cysteine- and glycine-rich LIM domain protein CRP2 result in subtle alteration of cardiac ultrastructure Julia F Sagave1, Markus Moser2, Elisabeth Ehler3, Sabine Weiskirchen1, Doris Stoll1, Kalle Günther4, Reinhard Büttner5 and Ralf Weiskirchen*1 Address: 1Institute of Clinical Chemistry and Pathobiochemistry, RWTH- University Hospital Aachen, Germany, 2Max Planck-Institute for Biochemistry, Martinsried, Germany, 3The Randall Division of Cell and Molecular Biophysics and The Cardiovascular Division, King's College London, UK, 4Qiagen, Hilden, Germany and 5Institute of Pathology, University Hospital Bonn, Germany Email: Julia F Sagave - [email protected]; Markus Moser - [email protected]; Elisabeth Ehler - [email protected]; Sabine Weiskirchen - [email protected]; Doris Stoll - [email protected]; Kalle Günther - [email protected]; Reinhard Büttner - [email protected]; Ralf Weiskirchen* - [email protected] * Corresponding author Published: 19 August 2008 Received: 19 March 2008 Accepted: 19 August 2008 BMC Developmental Biology 2008, 8:80 doi:10.1186/1471-213X-8-80 This article is available from: http://www.biomedcentral.com/1471-213X/8/80 © 2008 Sagave et al; licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Abstract Background: The cysteine and glycine rich protein 2 (CRP2) encoded by the Csrp2 gene is a LIM domain protein expressed in the vascular system, particularly in smooth muscle cells.
    [Show full text]
  • Unbiased Data Mining Identifies Cell Cycle Transcripts That Predict Non-Indolent Gleason Score 7 Prostate Cancer Wendy L
    Johnston et al. BMC Urology (2019) 19:4 https://doi.org/10.1186/s12894-018-0433-5 RESEARCHARTICLE Open Access Unbiased data mining identifies cell cycle transcripts that predict non-indolent Gleason score 7 prostate cancer Wendy L. Johnston1* , Charles N. Catton1,2 and Carol J. Swallow3,4,5,6 Abstract Background: Patients with newly diagnosed non-metastatic prostate adenocarcinoma are typically classified as at low, intermediate, or high risk of disease progression using blood prostate-specific antigen concentration, tumour T category, and tumour pathological Gleason score. Classification is used to both predict clinical outcome and to inform initial management. However, significant heterogeneity is observed in outcome, particularly within the intermediate risk group, and there is an urgent need for additional markers to more accurately hone risk prediction. Recently developed web-based visualization and analysis tools have facilitated rapid interrogation of large transcriptome datasets, and querying broadly across multiple large datasets should identify predictors that are widely applicable. Methods: We used camcAPP, cBioPortal, CRN, and NIH NCI GDC Data Portal to data mine publicly available large prostate cancer datasets. A test set of biomarkers was developed by identifying transcripts that had: 1) altered abundance in prostate cancer, 2) altered expression in patients with Gleason score 7 tumours and biochemical recurrence, 3) correlation of expression with time until biochemical recurrence across three datasets (Cambridge, Stockholm, MSKCC). Transcripts that met these criteria were then examined in a validation dataset (TCGA-PRAD) using univariate and multivariable models to predict biochemical recurrence in patients with Gleason score 7 tumours. Results: Twenty transcripts met the test criteria, and 12 were validated in TCGA-PRAD Gleason score 7 patients.
    [Show full text]
  • An Integrated Molecular Cytogenetic Map of Cucumis Sativus L
    Han et al. BMC Genetics 2011, 12:18 http://www.biomedcentral.com/1471-2156/12/18 RESEARCHARTICLE Open Access An integrated molecular cytogenetic map of Cucumis sativus L. chromosome 2 Yonghua Han1,2*, Zhonghua Zhang3, Sanwen Huang3, Weiwei Jin1* Abstract Background: Integration of molecular, genetic and cytological maps is still a challenge for most plant species. Recent progress in molecular and cytogenetic studies created a basis for developing integrated maps in cucumber (Cucumis sativus L.). Results: In this study, eleven fosmid clones and three plasmids containing 45S rDNA, the centromeric satellite repeat Type III and the pericentriomeric repeat CsRP1 sequences respectively were hybridized to cucumber metaphase chromosomes to assign their cytological location on chromosome 2. Moreover, an integrated molecular cytogenetic map of cucumber chromosomes 2 was constructed by fluorescence in situ hybridization (FISH) mapping of 11 fosmid clones together with the cucumber centromere-specific Type III sequence on meiotic pachytene chromosomes. The cytogenetic map was fully integrated with genetic linkage map since each fosmid clone was anchored by a genetically mapped simple sequence repeat marker (SSR). The relationship between the genetic and physical distances along chromosome was analyzed. Conclusions: Recombination was not evenly distributed along the physical length of chromosome 2. Suppression of recombination was found in centromeric and pericentromeric regions. Our results also indicated that the molecular markers composing the linkage map for chromosome 2 provided excellent coverage of the chromosome. Background compared to cucumber genome size. Of these, only Cucumber (Cucumis sativus L., 2n = 2x = 14) is an 72.8% of the assembled sequences were anchored onto economically important vegetable crop in the Cucurbita- the chromosomes using information from high density ceae family.
    [Show full text]
  • A Novel Role for CSRP1 in a Lebanese Family with Congenital Cardiac Defects
    A Novel Role for CSRP1 in a Lebanese Family with Congenital Cardiac Defects The Harvard community has made this article openly available. Please share how this access benefits you. Your story matters Citation Kamar, A., A. C. Fahed, K. Shibbani, N. El-Hachem, S. Bou-Slaiman, M. Arabi, M. Kurban, et al. 2017. “A Novel Role for CSRP1 in a Lebanese Family with Congenital Cardiac Defects.” Frontiers in Genetics 8 (1): 217. doi:10.3389/fgene.2017.00217. http:// dx.doi.org/10.3389/fgene.2017.00217. Published Version doi:10.3389/fgene.2017.00217 Citable link http://nrs.harvard.edu/urn-3:HUL.InstRepos:34868978 Terms of Use This article was downloaded from Harvard University’s DASH repository, and is made available under the terms and conditions applicable to Other Posted Material, as set forth at http:// nrs.harvard.edu/urn-3:HUL.InstRepos:dash.current.terms-of- use#LAA ORIGINAL RESEARCH published: 18 December 2017 doi: 10.3389/fgene.2017.00217 A Novel Role for CSRP1 in a Lebanese Family with Congenital Cardiac Defects Amina Kamar 1, Akl C. Fahed 2, 3, 4, Kamel Shibbani 5, Nehme El-Hachem 6, Salim Bou-Slaiman 5, Mariam Arabi 7, Mazen Kurban 5, 8, 9, Jonathan G. Seidman 2, Christine E. Seidman 2, 4, Rachid Haidar 10, Elias Baydoun 1*, Georges Nemer 3* and Fadi Bitar 7 1 Department of Biology, American University of Beirut, Beirut, Lebanon, 2 Department of Genetics, Harvard Medical School, Boston, MA, United States, 3 Department of Medicine, Massachusetts General Hospital, Boston, MA, United States, 4 Division of Cardiology, Howard Hughes Medical
    [Show full text]
  • CSRP2 Suppresses Colorectal Cancer Progression Via P130cas/Rac1 Axis
    Theranostics 2020, Vol. 10, Issue 24 11063 Ivyspring International Publisher Theranostics 2020; 10(24): 11063-11079. doi: 10.7150/thno.45674 Research Paper CSRP2 suppresses colorectal cancer progression via p130Cas/Rac1 axis-meditated ERK, PAK, and HIPPO signaling pathways Lixia Chen1,2, Xiaoli Long1,2, Shiyu Duan1,2, Xunhua Liu1,2, Jianxiong Chen1,2, Jiawen Lan1,2, Xuming Liu1, Wenqing Huang2, Jian Geng1,2 and Jun Zhou1,2 1. Department of Pathology, Nanfang Hospital, Southern Medical University, Guangzhou 510515, China. 2. Department of Pathology, School of Basic Medical Sciences, Southern Medical University, Guangzhou 510515, China. Corresponding authors: Jun Zhou, Department of Pathology, Nanfang Hospital, Southern Medical University, Guangzhou, 510515, China; Phone: 86-2062789365; E-mail: [email protected]; [email protected]; or, Jian Geng, Department of Pathology, Nanfang Hospital, Southern Medical University, Guangzhou, 510515, China; Phone: 86-2061648223; E-mail: geng@ smu.edu.cn. © The author(s). This is an open access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/). See http://ivyspring.com/terms for full terms and conditions. Received: 2020.03.05; Accepted: 2020.08.21; Published: 2020.09.02 Abstract Metastasis is a major cause of death in patients with colorectal cancer (CRC). Cysteine-rich protein 2 (CSRP2) has been recently implicated in the progression and metastasis of a variety of cancers. However, the biological functions and underlying mechanisms of CSRP2 in the regulation of CRC progression are largely unknown. Methods: Immunohistochemistry, quantitative real-time polymerase chain reaction (qPCR) and Western blotting (WB) were used to detect the expression of CSRP2 in CRC tissues and paracancerous tissues.
    [Show full text]
  • Integration of Lncrna and Mrna Transcriptome Analyses Reveals
    G C A T T A C G G C A T genes Article Integration of lncRNA and mRNA Transcriptome Analyses Reveals Genes and Pathways Potentially Involved in Calf Intestinal Growth and Development during the Early Weeks of Life Eveline M. Ibeagha-Awemu 1,*, Duy N. Do 1,2, Pier-Luc Dudemaine 1, Bridget E. Fomenky 1,3 and Nathalie Bissonnette 1 ID 1 Agriculture and Agri-Food Canada, Sherbrooke Research and Development Centre, Sherbrooke, QC J1M 0C8, Canada; [email protected] (D.N.D.); [email protected] (P.-L.D.); [email protected] (B.E.F.); [email protected] (N.B.) 2 Department of Animal Science, McGill University, Ste-Anne-De Bellevue, QC H9X 3V9, Canada 3 Département des Sciences Animales, Université Laval, Québec, QC G1V 0A9, Canada * Correspondence: [email protected]; Tel.: +1-819-780-7249 Received: 12 November 2017; Accepted: 21 February 2018; Published: 5 March 2018 Abstract: A better understanding of the factors that regulate growth and immune response of the gastrointestinal tract (GIT) of calves will promote informed management practices in calf rearing. This study aimed to explore genomics (messenger RNA (mRNA)) and epigenomics (long non-coding RNA (lncRNA)) mechanisms regulating the development of the rumen and ileum in calves. Thirty-two calves (≈5-days-old) were reared for 96 days following standard procedures. Sixteen calves were humanely euthanized on experiment day 33 (D33) (pre-weaning) and another 16 on D96 (post-weaning) for collection of ileum and rumen tissues. RNA from tissues was subjected to next generation sequencing and 3310 and 4217 mRNAs were differentially expressed (DE) between D33 and D96 in ileum and rumen tissues, respectively.
    [Show full text]
  • Characterization and Sequence Analysis of Cysteine and Glycine-Rich Protein 3 in Egyptian Native Cattle and River Native Buffalo Cdna Sequences
    African Journal of Biotechnology Vol. 10(16), pp. 3055-3061, 18 April, 2011 Available online at http://www.academicjournals.org/AJB DOI: 10.5897/AJB10.1953 ISSN 1684–5315 © 2011 Academic Journals Full Length Research Paper Characterization and sequence analysis of cysteine and glycine-rich protein 3 in Egyptian native cattle and river native buffalo cDNA sequences Ahlam A. Abou Mossallam, Nevien M. Sabry, Eman R. Mahfouz*, Mona A. Bibars and Soheir M. El Nahas Department of Cell Biology, Genetic Engineering Division, National Research Center, Dokki, Giza, Egypt. Accepted 3 February, 2011 Cysteine and glycine rich protein, CSRP3 also referred to as the muscle LIM protein (MLP), has been investigated in native Egyptian cattle and buffalo (river buffalo). RNA extraction and cDNA synthesis were conducted from different tissue samples. Primers specific for CSRP3 were designed using known cDNA sequences of Bos taurus published in database with different accession numbers. Polymerase chain reaction (PCR) was performed and products were purified and sequenced. Sequence analysis and alignment were carried out using CLUSTAL W (1.83). Multiple nucleotide sequence alignment between CSRP3 cDNA amplicons of native buffalo and cattle revealed 89% identity. B. taurus CSRP3 mRNA (Cardiac LIM protein) [NM 001024689.2] showed 85 and 87% identity in nucleic acid sequences and 82 and 84% homology in amino acid sequences with native cattle and buffalo, respectively. A 90% homology was detected between the amino acid sequences of river buffalo and native cattle. Fourty nine translated amino acids out of 51 in both buffalo and cattle are found to be part of the conserved CSRP3 LIM1 domain protein which comprises 57 codons.
    [Show full text]
  • Loss of LMOD1 Impairs Smooth Muscle Cytocontractility and Causes
    Loss of LMOD1 impairs smooth muscle cytocontractility PNAS PLUS and causes megacystis microcolon intestinal hypoperistalsis syndrome in humans and mice Danny Halima,1, Michael P. Wilsonb,1, Daniel Oliverc, Erwin Brosensa, Joke B. G. M. Verheijd, Yu Hanb, Vivek Nandab, Qing Lyub, Michael Doukase, Hans Stoope, Rutger W. W. Brouwerf, Wilfred F. J. van IJckenf, Orazio J. Slivanob, Alan J. Burnsa,g, Christine K. Christieb, Karen L. de Mesy Bentleyh, Alice S. Brooksa, Dick Tibboeli, Suowen Xub, Zheng Gen Jinb, Tono Djuwantonoj, Wei Yanc, Maria M. Alvesa, Robert M. W. Hofstraa,g,2, and Joseph M. Mianob,2 aDepartment of Clinical Genetics, Erasmus University Medical Center, 3015 CN Rotterdam, The Netherlands; bAab Cardiovascular Research Institute, University of Rochester School of Medicine and Dentistry, Rochester, NY 14642; cDepartment of Physiology and Cell Biology, University of Nevada School of Medicine, Reno, NV 89557; dDepartment of Genetics, University Medical Center, University of Groningen, 9700 RB Groningen, The Netherlands; eDepartment of Pathology, Erasmus University Medical Center, 3015 CN Rotterdam, The Netherlands; fCenter for Biomics, Erasmus University Medical Center, 3015 CN Rotterdam, The Netherlands; gStem Cells and Regenerative Medicine, Birth Defects Research Centre, University College London Institute of Child Health, London WC1N 1EH, United Kingdom; hDepartment of Pathology and Laboratory Medicine, University of Rochester School of Medicine and Dentistry, Rochester, NY 14642; iDepartment of Pediatric Surgery, Erasmus University Medical Center, 3015 CN Rotterdam, The Netherlands; and jDepartment of Obstetrics and Gynecology, Faculty of Medicine, Universitas Padjadjaran, Bandung, Indonesia Edited by Eric N. Olson, University of Texas Southwestern Medical Center, Dallas, TX, and approved February 21, 2017 (received for review December 13, 2016) Megacystis microcolon intestinal hypoperistalsis syndrome (MMIHS) is lacking (6, 7).
    [Show full text]