RASGRP2 Antibody Cat. No.: 16-023

RASGRP2 Antibody

Specifications

HOST SPECIES: Rabbit

SPECIES REACTIVITY: Human

Recombinant fusion protein containing a sequence corresponding to amino acids 1-200 of IMMUNOGEN: human RASGRP2 (NP_722541.1).

TESTED APPLICATIONS: WB

APPLICATIONS: WB: ,1:200 - 1:2000

POSITIVE CONTROL: 1) 293T

2) LO2

PREDICTED MOLECULAR Observed: 69kDa WEIGHT:

Properties

PURIFICATION: Affinity purification

CLONALITY: Polyclonal

ISOTYPE: IgG

CONJUGATE: Unconjugated

September 24, 2021 1 https://www.prosci-inc.com/rasgrp2-antibody-16-023.html PHYSICAL STATE: Liquid

BUFFER: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

STORAGE CONDITIONS: Store at -20˚C. Avoid freeze / thaw cycles.

Additional Info

OFFICIAL SYMBOL: RASGRP2

CALDAG-GEFI, CDC25L, RAS guanyl-releasing protein 2, F25B3.3 kinase-like protein, RAS guanyl nucleotide-releasing protein 2, RAS guanyl releasing protein 2 (calcium and DAG- ALTERNATE NAMES: regulated), calcium and DAG-regulated guanine nucleotide exchange factor I, calcium and diacylglycerol-regulated guanine nucleotide exchange factor I, cdc25-like protein, guanine exchange factor MCG7

GENE ID: 10235

USER NOTE: Optimal dilutions for each application to be determined by the researcher.

Background and References

The protein encoded by this gene is a brain-enriched nucleotide exchanged factor that contains an N-terminal GEF domain, 2 tandem repeats of EF-hand calcium-binding motifs, and a C-terminal diacylglycerol/phorbol ester-binding domain. This protein can activate BACKGROUND: small GTPases, including RAS and RAP1/RAS3. The nucleotide exchange activity of this protein can be stimulated by calcium and diacylglycerol. Four alternatively spliced transcript variants encoding two different isoforms have been found for this gene.

ANTIBODIES FOR RESEARCH USE ONLY.

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September 24, 2021 2 https://www.prosci-inc.com/rasgrp2-antibody-16-023.html