RASGRP2 Antibody Cat

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RASGRP2 Antibody Cat. No.: 16-023 RASGRP2 Antibody Specifications HOST SPECIES: Rabbit SPECIES REACTIVITY: Human Recombinant fusion protein containing a sequence corresponding to amino acids 1-200 of IMMUNOGEN: human RASGRP2 (NP_722541.1). TESTED APPLICATIONS: WB APPLICATIONS: WB: ,1:200 - 1:2000 POSITIVE CONTROL: 1) 293T 2) LO2 PREDICTED MOLECULAR Observed: 69kDa WEIGHT: Properties PURIFICATION: Affinity purification CLONALITY: Polyclonal ISOTYPE: IgG CONJUGATE: Unconjugated September 24, 2021 1 https://www.prosci-inc.com/rasgrp2-antibody-16-023.html PHYSICAL STATE: Liquid BUFFER: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. STORAGE CONDITIONS: Store at -20˚C. Avoid freeze / thaw cycles. Additional Info OFFICIAL SYMBOL: RASGRP2 CALDAG-GEFI, CDC25L, RAS guanyl-releasing protein 2, F25B3.3 kinase-like protein, RAS guanyl nucleotide-releasing protein 2, RAS guanyl releasing protein 2 (calcium and DAG- ALTERNATE NAMES: regulated), calcium and DAG-regulated guanine nucleotide exchange factor I, calcium and diacylglycerol-regulated guanine nucleotide exchange factor I, cdc25-like protein, guanine exchange factor MCG7 GENE ID: 10235 USER NOTE: Optimal dilutions for each application to be determined by the researcher. Background and References The protein encoded by this gene is a brain-enriched nucleotide exchanged factor that contains an N-terminal GEF domain, 2 tandem repeats of EF-hand calcium-binding motifs, and a C-terminal diacylglycerol/phorbol ester-binding domain. This protein can activate BACKGROUND: small GTPases, including RAS and RAP1/RAS3. The nucleotide exchange activity of this protein can be stimulated by calcium and diacylglycerol. Four alternatively spliced transcript variants encoding two different isoforms have been found for this gene. ANTIBODIES FOR RESEARCH USE ONLY. For additional information, visit ProSci's Terms & Conditions Page. September 24, 2021 2 https://www.prosci-inc.com/rasgrp2-antibody-16-023.html.

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