Funded by the National Institute on Drug Abuse

Third National Conference Stress and Addiction: From Molecule to Neighborhood

Wyndham Miami Beach Resort 4833 Collins Avenue Miami Beach, FL 33140

October 2-4, 2003 Funded by the National Institute on Drug Abuse

Third National Conference Stress and Addiction: From Molecule to Neighborhood

Wyndham Miami Beach Resort 4833 Collins Avenue Miami Beach, FL 33140

October 2-4, 2003 National Hispanic Science Network on Drug Abuse

Mission Statement

he National Hispanic Science Network on TDrug Abuse is dedicated to improving the health of Hispanics by:

1) Increasing the amount and quality of interdisciplinary translational research on drug abuse; and,

2) Fostering the development of Hispanic scientists in drug abuse research.

2 National Steering Committee

José Szapocznik, Ph.D. Patricia Molina, M.D., Ph.D. Chair, NHSN Associate Professor Professor & Director Department of Psychology Center for Family Studies Louisiana State University Department of Psychiatry & Behavioral Sciences University of Miami School of Medicine J. Bryan Page, Ph.D. Professor and Chair Hortensia Amaro, Ph.D. Department of Anthropology Distinguished Professor & Director University of Miami Institute on Urban Health Research Bouvé College of Health Sciences Northeastern University Rafaela R. Robles, Ed.D. Professor Department of Community Health Ana Mari Cauce, Ph.D. Universidad Central del Caribe Professor and Chair Department of Psychology University of Washington Daniel Santisteban, Ph.D. Associate Professor Department of Psychiatry & Behavioral Sciences Alexander Kopelowicz, M.D. University of Miami School of Medicine Associate Professor Department of Psychiatry University of California at Los Angeles Avelardo Valdéz, Ph.D. Professor Graduate School of Social Work Joe L. Martínez, Ph.D. University of Houston Ewing Halsell Professor of Neuroscience Department of Biology University of Texas at San Antonio William A. Vega, Ph.D. Professor Department of Psychiatry UMDNJ/ Robert Wood Johnson Medical School

3 Thursday, October 2, 2003 Scientific Program

8:00 a.m. - 5:30 p.m. Registration Grand Promenade Foyer, Lobby Level

12:00 p.m. - 1:30 p.m. Opening Luncheon Grand Promenade Room, Lobby Level

Welcoming José Szapocznik, Ph.D. Remarks: Chair, NHSN University of Miami School of Medicine

Ana Anders, L.I.C.S.W. Senior Advisor, Special Populations Office National Institute on Drug Abuse

Conference William A. Vega, Ph.D. Overview: Chair, NHSN 2003 Conference Planning Subcommittee UMDNJ/ Robert Wood Johnson Medical School

Featured Andrea Barthwell, M.D., F.A.S.A.M. Speaker: Deputy Director for Demand Reduction White House Office of National Drug Control Policy

1:30 p.m. - 1:45 p.m. BREAK

*** All presentations in Regency Ballroom, Lobby Level***

1:45 p.m. - 3:30 p.m. Putative Social and Biologic Mechanisms Affecting the Stress Relationship to Drug Abuse

Chair & Joe L. Martínez, Ph.D. Discussant: University of Texas at San Antonio

Presenters: Patricia Molina, M.D., Ph.D. Louisiana State University “Neurobiology of the Stress Response”

William A. Vega, Ph.D. UMDNJ/ Robert Wood Johnson Medical School “Stress and Cultural Adaptation: Why are Latino Drug Use Rates Higher in the U.S. than in Nations of Origin?”

Avelardo Valdéz, Ph.D. University of Houston “Social Capital, Substance Use and Stress”

4 Thursday, October 2, 2003 Scientific Program

3:30 p.m. - 3:45 p.m. BREAK

3:45 p.m. - 5:30 p.m. Predisposing Factors and Neurobiologic Substrates

Chair & George A. Ricaurte, M.D., Ph.D. Discussant: Johns Hopkins University

Presenters: Jon Kar Zubieta, Ph.D. University of Michigan “Brain Circuits in Addiction“

Kathleen Ries Merikangas, Ph.D. National Institute of Mental Health ”Migrant Study of Substance Use Disorders in Puerto Rican Families“

María Elena Medina-Mora, Ph.D. National Institute of Psychiatry of Mexico “Differences in U.S.-Mexico Drug Use Patterns Based on the Results of the National Household Surveys on Addictions and Other Studies”

5:30 p.m. Adjourn Scientific Program

5:30 p.m. - 6:00 p.m. NHSN Membership Photo Session Grand Promenade Room, Lobby Level All NHSN Scientist and Student Members, please proceed to the Grand Promenade Room where group photographs will be taken.

6:00 p.m. - 7:00 p.m. BREAK

7:00 p.m. - 9:00 p.m. Dinner and Awards Ceremony Starlight Ballroom, 18th Floor

Hortensia Amaro, Ph.D. Northeastern University

William A. Vega, Ph.D. UMDNJ/ Robert Wood Johnson Medical School

9:00 p.m. - 11:00 p.m. Social Event Starlight Ballroom, 18th Floor

5 Friday, October 3, 2003 Scientific Program

8:00 a.m. - 9:00 a.m. Breakfast Grand Promenade Room, Lobby Level

8:00 a.m. - 5:30 p.m. Registration Grand Promenade Foyer, Lobby Level

8:00 a.m. - 5:30 p.m. Poster Session Mediterranean Room Center, Lobby Level Posters available for viewing all day. See pages 12 & 13 for Poster titles and authors.

*** All presentations in Regency Ballroom, Lobby Level***

9:00 a.m. - 10:00 a.m. Keynote Address

Nora Volkow, M.D. Director, National Institute on Drug Abuse

10:00 a.m. - 10:15 a.m. BREAK

10:15 a.m. - 12:15 p.m. Prevention Science: Cultural Relevance from Molecular Mechanisms to Community Interventions

Chair & Felipe González-Castro, Ph.D. Discussant: Arizona State University

Presenters: William A. Carlezon, Ph.D. Harvard University “Biological Mechanisms of Aversive States in Drug Addiction”

Hilda Pantín, Ph.D. University of Miami School of Medicine “Familias Unidas: A Preventive Intervention for Latino Adolescents and Families in Urban Environments”

Charles Martínez, Ph.D. Oregon Social Learning Center “Adapting Preventive Intervention Models for Communities Undergoing Rapid Sociodemographic Shifts”

12:15 p.m. - 1:45 p.m. Mentoring Luncheon Grand Promenade Room, Lobby Level Seating for the Mentoring Luncheon has been pre-arranged based on information provided by the conference participants. Please refer to the seating chart in your registration packet for your assigned table.

6 Friday, October 3, 2003 Scientific Program

1:45 p.m. - 2:00 p.m. BREAK

2:00 p.m. - 4:00 p.m. Multiple Levels of Intervention Targets in Addiction Treatment and Relapse Prevention

Chair & Daniel Santisteban, Ph.D. Discussant: University of Miami School of Medicine

Presenters: Diana Martínez, M.D. Columbia University “Imaging the Neurobiology of Addiction”

Hortensia Amaro, Ph.D. Northeastern University “Treatment Retention Among Hispanic Women: Findings and Questions for Future Research”

Rafaela R. Robles, Ed.D. Universidad Central del Caribe “Effects of a Two-Facet Intervention to Reduce HIV Risk Behaviors Among Hispanic Drug Injectors in Puerto Rico: A Randomized Controlled Study”

4:00 p.m. Adjourn Scientific Program

4:00 p.m. - 5:30 p.m. Poster Session and Reception Mediterranean Room Center, Lobby Level

Chair: Charles Martínez, Ph.D. Oregon Social Learning Center

Co-Chair: Steve R. López, Ph.D. University of California at Los Angeles

See pages 12 & 13 for Poster titles and authors.

7 Saturday, October 4, 2003

8:00 a.m. - 9:00 a.m. Breakfast Grand Promenade Room, Lobby Level

9:00 a.m. - 10:30 a.m. National Network Meeting: National Strategic Plan on Hispanic Drug Abuse Research

Chair: Hortensia Amaro, Ph.D. Northeastern University

10:30 a.m. - 10:45 a.m. BREAK

10:45 a.m. - 12:00 p.m National Network Meeting: National Strategic Plan (Continued)

12:00 p.m - 12:45 p.m. Working Lunch - National Network Meeting: National Strategic Plan

12:45 p.m. Adjourn National Network Meeting

12:45 p.m. - 1:00 p.m. BREAK

1:00 p.m. - 3:00 p.m. Research Funding and Career Development Workshop

Co-Chair: Angela Pattatucci-Aragón, Ph.D. University of Puerto Rico

Co-Chair: Iván Montoya, M.D., M.P.H. National Institute on Drug Abuse

New Funding Priorities and Initiatives

Chair: Iván Montoya, M.D., M.P.H. National Institute on Drug Abuse

Panelists: Jerry Flanzer, D.S.W. National Institute on Drug Abuse

Eleanor McLellan-Lemal, M.A. Centers for Disease Control and Prevention

Susan F. Newcomer, Ph.D. National Institute of Child Health & Human Development

Tracy Enright Patterson, M.A. Wake Forest University School of Medicine Robert Wood Johnson Foundation

Mónica S. Ruiz, Ph.D., M.P.H. National Institute of Allergy and Infectious Diseases

8 Saturday, October 4, 2003

3:00 p.m. - 3:15 p.m. BREAK

3:15 p.m. - 5:00 p.m. Research Funding and Career Development Workshop (Continued)

Grant Review and Grant Post-Submission Issues

Panel Chair: Eduardo Montalvo, Ph.D. Center for Scientific Review National Institutes of Health

Panelists: Alexander N. Ortega, Ph.D., M.P.H. Ohio State University

Jesús Ramírez Vallez, Ph.D. University of Illinois

Mildred Vera, Ph.D. University of Puerto Rico

María Cecilia Zea, Ph.D. George Washington University

5:00 p.m. Adjourn Research Funding and Career Development Workshop

9 ABSTRACTS

Putative Social and Biologic Mechanisms Affecting the Stress Relationship to Drug Abuse

Chair & Discussant: Joe L. Martínez, Jr., Ph.D. University of Texas at San Antonio

Stress contributes to drug abuse in at least two ways: by influencing brain function directly, and through psychological mediation. Patricia E. Molina, M.D., Ph.D., will review evidence indicating that physical and psychological stress is associated with a higher incidence of drug abuse. In particular, the hippocampus is a sensitive target for the damage produced by the stress response. The challenge remains to understand how this structure may contribute to drug abuse in vulnerable individuals. Avelardo Valdéz, Ph.D., will illustrate how a measure of social capital may mediate the relationship of stress as an antecedent to substance use and other risk behaviors. William Vega, Ph.D., will review evidence for a "Hispanic paradox" in drug abuse, including epidemiologic findings that support a social stress and social assimilation explanation. Risk factors for immigrants and U.S.-born Latinos will be examined.

Predisposing Factors and Neurobiologic Substrates

Chair & Discussant: George A. Ricaurte, M.D., Ph.D. Johns Hopkins University

The cost of drug abuse and dependence to the individual and society are enormous. Yet, the factors that influence and predispose to drug use, abuse and dependence remain poorly understood. This panel will address cultural influences, familial risk factors, and neurobiologic substrates of licit and illicit drug abuse and dependence. The important issue of comorbidities will also be addressed. A better understanding of the factors that lead to and influence the course of drug dependence is an essential first step toward the successful treatment of drug addiction.

10 ABSTRACTS

Prevention Science: Cultural Relevance from Molecular Mechanisms to Community Interventions

Chair & Discussant: Felipe González-Castro, Ph.D. Arizona State University

This panel will examine contemporary models and approaches to drug abuse as seen across levels of analysis ranging from molecular, to physiology, to family, and to com- munity. The objectives will be: (1) to present novel approaches relevant to science rang- ing from basic science to prevention science as examined across these various levels, and to identify common threads of relevant knowledge; and (2) to examine emerging scien- tific knowledge that may be harnessed for the purpose of increasing the efficacy and effectiveness, as well as the cultural relevance, of prevention interventions as applied with various Hispanic/Latino populations. Challenges across areas, from molecular, to neurophysiology, to family, to community will be examined, with the aim of identifying meaningful directions for new research, and for the development of more potent and culturally relevant prevention interventions.

Multiple Levels of Intervention Targets in Addiction Treatment and Relapse Prevention

Chair & Discussant: Daniel Santisteban, Ph.D. University of Miami School of Medicine

The successful treatment of addiction and prevention of relapse is likely to require a full arsenal of interventions targeting different change mechanisms and levels of interven- tion. Research has yet to succeed in matching specific levels of interventions (pharma- cological, individual psychosocial, and community-focused) to specific client character- istics and clinical situations. Further, individuals with more severe profiles of addiction and co-occurring disorders may require more intensive and multifaceted intervention approaches. The purpose of this panel on addiction treatment and relapse prevention is to present different perspectives in the conceptualization and treatment of core addic- tion processes. The panel will present on the neurobiology of addiction and its implica- tions for treatment, on the impact of individually-oriented psychosocial interventions, and on the impact of community-level enhancements to treatment.

11 POSTER

1 Sex, Drugs and HIV Among Farm Workers in Windham County, CT Juhem Navarro, Claudia Santelices, Michael Duke, Anna Marie Nicolaysen & Johan Galarza, Center for Community Health Research, Hispanic Health Council, Hartford, CT, & Karla de la Torre, University of Puerto Rico

2 NMDA Receptor Involvement in Opiate-Induced Neural and Behavioral Plasticity: Studies with Morphine, Buprenorphine and Methadone Ian A. Méndez & Keith A. Trujillo, Ph.D., California State University at San Marcos 3 Self-Administration of Heroin in Rats: Effects of Low-Level Lead Exposure During Gestation and Lactation Angélica Rocha, Rodrigo Valles, Aaron L. Cardon, Gerald R. Bratton, & Jack R. Nation, Ph.D., Texas A&M University

4 Perinatal Lead Exposure Alters Morphine Conditioned Place Preference Rodrigo Valles, Aaron L. Cardon, Gerald R. Bratton, & Jack R. Nation, Ph.D., Texas A&M University 5 Drug Use and Sexual Risk Among Hispanic Men Who Have Sex With Men in South Florida M. Isabel Fernández, Ph.D., Tatiana Perrino, Psy.D. & G. Stephen Bowen, M.D., M.P.H., University of Miami School of Medicine, & Debra A. Murphy, Ph.D., University of California at Los Angeles

6 Stress and Substance Use Risk in High Risk Hispanic Students Raúl Calderón, Jr., Ph.D. & Gregory Smith, University of Kentucky, & Marilyn Winkleby, Stanford University School of Medicine

7 A Bi-Dimensional Model of Acculturation for Examining Differences in Family Functioning, Behavior Problems, and Drug Use Intentions in Hispanic Immigrant Adolescents Summer Sullivan, M.S., Guillermo Prado, M.S., & Hilda Pantín, Ph.D., University of Miami School of Medicine

8 Preliminary Evidence Supporting the Efficacy of “Familias Unidas” in Reducing Behavior Problems, Drug Abuse, and Sexual Behavior in Hispanic Behavior Problem Adolescents Guillermo Prado, M.S., Summer Sullivan, M.S., & Hilda Pantín, Ph.D., University of Miami School of Medicine

9 Gender Differences in Conduct Disorders, Substance Abuse, and Sexual Behavior in Hispanic Adolescents Andrea Elfmont, Nichole Lupei, Summer Sullivan, M.S., & Guillermo Prado, M.S., University of Miami School of Medicine

12 SESSION

10 High Rates of Co-Occurring Psychiatric and Substance Abuse Symptoms Among Urban HIV+ Adults Screened Within an HIV Primary Care Setting Tomás Soto, Ph.D., & Carolyn Mildner, Ph.D., The CORE Center, Cook County Bureau of Health Services, Chicago, IL

11 Understanding the Specifics of Family Acculturation Processes and How This Plays a Role in Hispanic Youth Behavioral Problems Jessica Ríos, University of Miami 12 Internet Counseling for Hispanic, 7th Grade Children From the Texas Valley Lisa Cepeda & Collie W. Conoley, Ph.D., Texas A&M University

13 Snorting Brown: Contextual Factors and the Process of Addiction Among Chicano Non-Injecting Heroin Users Avelardo Valdéz, Ph.D., University of Houston, & Alice Cepeda, City University of New York Graduate Center

14 Nervios y Ataques: The Emic Nature of Stress in the Dominican Republic Rosemary Díaz, University of Connecticut

15 Latino Father-Youth Relationship: Risk and Protective Factors Diana Naranjo & Felipe González Castro, Ph.D., Arizona State University 16 F344 Rats Self-Administer Methamphetamine but not Amphetamine into the Nucleus Accumbens Via Reverse Microdialysis Jesse S. Rodríguez, Sherin Y. Boctor, Clyde F. Phelix, Ph.D. & Joe Martínez, Jr., Ph.D., University of Texas at San Antonio 17 Acculturation: A Latent Class Dynamic Approach and its Implications for Substance Use Prevention Research Mildred Maldonado-Molina, Douglas Coatsworth, Ph.D., & Linda M. Collins, Ph.D., The Pennsylvania State University

18 The Role of CART Peptides in the Motivational and Addictive Properties of Psychostimulants Pastor R. Couceyro, Ph.D., & Charity Evans, Chicago Medical School, &Audra McKinzie, Jim Douglass & Anthony W. Bannon, Amgen, Inc., Thousand Oaks, CA

19 Development and Overview of a Smoking Cessation Program for Latino Youth Susana Nemes, Ph.D., Danya International Inc., Silver Spring, MD

13 ABSTRACTS

National Strategic Plan on Hispanic Drug Abuse Research Chair: Hortensia Amaro, Ph.D. Northeastern University

Over the last year, a panel of scientific experts developed a national strategic plan to direct the future of Hispanic drug abuse research. This session will present the background and process followed for the development of the national strategic plan and the major recommendations contained therein. We will also discuss immediate and long-term plans for dissemination of the strategic plan and the next phase of activ- ities to ensure that the recommendations are considered by the National Institute on Drug Abuse, Robert Wood Johnson Foundation, other funding sources and Congress. We expect that the National Strategic Plan will have an important impact on identified funding priorities and help scientists focus on the most critical research questions and scientific opportunities.

The development of the National Strategic Plan on Hispanic Drug Abuse Research was funded by a one- year grant from the Robert Wood Johnson Foundation. An Expert Panel chaired by Dr. Hortensia Amaro was responsible for development of the plan.

Research Funding Opportunities and Career Development Workshop Chair: Angela Pattatucci-Aragón, Ph.D. University of Puerto Rico

Co-Chair: Iván Montoya, M.D., M.P.H. National Institute on Drug Abuse

The Funding Opportunities and Career Development Workshop provides information to NHSN members on the preparation and submission of research proposals and addresses issues associated with career development. Last year the workshop focused on pre-submission issues, such as grant-writing techniques and the preparation of research proposals. The workshop this year builds upon that foundation by pro- viding important information on post-submission issues, such as how program officers can assist investi- gators and how to interpret the outcome of scientific review. Two panels are presented to accomplish this goal. The first is a group of funding agency representatives from the National Institute on Drug Abuse (NIDA), National Institute of Child Health and Human Development (NICHD), National Institute of Allergy and Infectious Diseases (NIAID), Centers for Disease Control and Prevention (CDC), and the Robert Wood Johnson Foundation (RWJF). Workshop attendees will learn about the focus of the different agencies, how they differ and how they are similar in grant submission and awarding procedures, and how program officers and other support personnel at the agencies can assist investigators in the proposal writing and submission process. The second panel consists of a Scientific Review Administrator (SRA) from the Center for Scientific Review at the National Institutes of Health and individuals currently serv- ing as members of scientific review committees. Workshop attendees will learn about how their research proposal is reviewed, the criteria used for evaluation, and how to interpret the outcome of scientific review -- priority scores, percentile rankings, and summary statements/critiques. Ample time for questions will be provided.

14 Expert Panel National Strategic Plan on Hispanic Drug Abuse Research

Hortensia Amaro, Ph.D. Rafaela R. Robles, Ed.D. Chair, Expert Panel Professor Distinguished Professor & Director Department of Community Health Institute on Urban Health Research Universidad Central del Caribe Bouvé College of Health Sciences Northeastern University Daniel Santisteban, Ph.D. Associate Professor Margarita Alegría, Ph.D. Department of Psychiatry & Behavioral Sciences Director University of Miami School of Medicine Center for Multicultural Mental Health Research Cambridge Health Alliance José Szapocznik, Ph.D. Harvard Medical School Professor and Director Center for Family Studies Glorisa Canino, Ph.D. Department of Psychiatry & Behavioral Sciences Professor & Director University of Miami Behavioral Sciences Research Institute University of Puerto Rico Keith Trujillo, Ph.D. Associate Professor Felipe González-Castro, Ph.D. Department of Psychology Professor California State University at San Marcos Department of Psychology Arizona State University Avelardo Valdéz, Ph.D. Professor Ernest Marquez, Ph.D. Graduate School of Social Work Director University of Houston Office for Special Populations National Institute of Mental Health

Joe L. Martínez, Ph.D. Project Director Ewing Halsell Professor of Neuroscience Amanda M. Navarro, M.P.H. Department of Biology School of Public Health University of Texas at San Antonio University of Texas at Houston Angela Pattatucci-Aragón, Ph.D. Professor Graduate School of Public Health University of Puerto Rico

15 Keynote Speaker

Nora D. Volkow, M.D.

Nora D. Volkow, M.D. is the Director of the National Institute on Drug Abuse (NIDA). Before assuming this position on May 1, 2003, Dr. Volkow was Associate Director for Life Sciences at Brookhaven National Laboratory (BNL), Director of Nuclear Medicine at BNL and Director of the NIDA-Department of Energy Regional Neuroimaging Center at BNL. She was also Professor at the Department of Psychiatry, State University of New York (SUNY) at Stony Brook and Associate Dean for the Medical School at SUNY-Stony Brook. Dr. Volkow received her M.D. in 1981 from the National University of Mexico, in Mexico City, Mexico, and performed her residency in psychiatry at New York University.

Her main area of interest is the investigation of the mechanisms underlying the reinforcing, addictive, and toxic properties of drugs of abuse in the human brain. Dr Volkow was the first to use imaging to investigate the neurochemical changes in the human brain that occur during drug addiction. Her studies have documented a decrease in function of the dopamine system in addicted subjects that is associated with a disruption in function of frontal brain regions involved in motivation and drive. Her work has also focused on the investigation of the neuro- chemical mechanisms responsible for intersubject variability in response to drugs of abuse and its potential link to vulnerability to drug abuse and alcoholism.

Dr. Volkow has also used imaging to investigate the effects of stimulant drugs with respect to both their reward- ing as well as therapeutic actions. By doing a systematic comparison of the pharmacological effects of cocaine (one of the most addictive drugs of abuse) and of methylphenidate (a drug used to treat children with attention deficit hyper- activity disorder) in the human brain, her studies have highlighted the relevance that drug pharmacokinetics play in enabling the reinforcing effects of stimulant drugs to occur. These studies have also shown that stimulant drugs, when used therapeutically, amplify dopamine signals in the brain, enhancing the saliency of a stimulus and thus improving attention and performance.

She has also used imaging to investigate the changes in the dopamine system that occur with aging and their func- tional significance. Her work has documented that the loss of dopamine brain function with age in healthy subjects with no evidence of neurological dysfunction is nonetheless associated with motor slowing and with changes in per- formance of cognitive tasks that involve executive functions. Her work now focuses on strategies to minimize the age- related losses in dopamine brain activity as a means to improve quality of life in the elderly.

Dr. Volkow has authored or coauthored more than 280 peer-reviewed publications, three edited books, and more than 50 book chapters and non-peer reviewed manuscripts. She is the recipient of multiple awards for her research, and has been elected to membership in the Institute of Medicine of the National Academy of Sciences. Dr. Volkow was named "Innovator of the Year" in 2000 by U.S. News and World Report.

16 Featured Speaker

Andrea Barthwell, M.D., F.A.S.A.M.

Andrea Grubb Barthwell, M.D., F.A.S.A.M., was nominated to serve as Deputy Director of Demand Reduction for the Office of National Drug Control Policy by President George W. Bush in December 2001 and confirmed by the United States Senate on January 28, 2002. Dr. Barthwell serves as a principal advisor to ONDCP Director John P. Walters on strategies, priorities, objectives, and goals pertaining to demand reduction poli- cies within the National Drug Control Strategy. As incumbent, Dr. Barthwell provides executive leadership of the Office of Demand Reduction and is responsible for oversight of demand reduc- tion aspects of the Strategy.

Dr. Barthwell's career has comprised a unique balance of research and practice related to substance abuse treatment. She has focused on the impact of substance abuse on our nation's communities and on finding ways to bring inno- vative, leading-edge care to individuals in those communities. As an author and lecturer on the methods employed in providing effective sub- stance abuse treatment, she focuses on the connection with violence, cultural issues and infectious diseases. Most recently she was the faculty member of the National Judicial College, Reno, Nevada where she taught and developed the Drug Court and Mental Health Court courses.

Dr. Barthwell received a Bachelor of Arts in Psychology from Wesleyan University in Connecticut and a Doctor of Medicine from the University of Michigan Medical School. Following post graduate training at the University of Chicago and Northwestern University Medical Center, she began her practice in the Chicago area. Prior to her appointment, she served as President of the Encounter Medical Group, President/CEO of the BRASS Foundation, and Executive Vice President/CCO for Human Resources Development Institute. She was also the Medical Director of TASC-Illinois and a special consultant to the Cook County Juvenile Drug Court Program. A founding member of the Chicago Area AIDS Task Force, Dr. Barthwell hosted a weekly local cable show on AIDS. She served two terms as pres- ident of the Illinois Society of Addiction Medicine and is the immediate Past President of the Board of Directors of the American Society of Addiction Medicine, a physician membership organization dedicated to improving and expand- ing the delivery of state-of-the-art addiction medicine services to all people.

Reflecting her commitment to merging scientific validity with practice, Dr. Barthwell has combined involvement in governmental policy with community-based work in organizations dealing with the human side of addiction. Her work with ethnic minorities, HIV/AIDS, and women with children has focused on assisting individuals to become responsible members of society. She is a former member of the National Advisory Council of the National Institute of Drug Abuse, the Center for Substance Abuse Treatment and the Drug Abuse Advisory Committee of the U.S. Food and Drug Administration. In 1997, Dr. Barthwell was selected by her peers as one of the "Best Doctors in America" in Addiction Medicine.

17 Presenters

Hortensia Amaro, Ph.D.

Hortensia Amaro received her Ph.D. in Psychology from the University of California, Los Angeles in 1982. She is currently Distinguished Professor at the Bouvé College of Health Sciences and Director of the Institute on Urban Health Research at Northeastern University. She has published over 65 scientific publications on: epidemiological and com- munity-based studies of alcohol and drug use among adolescents and adults; effectiveness of HIV/AIDS prevention programs; and substance abuse treatment of women. She is a member of the New England Node of the NIDA Clinical Trials Network. This research has been supported by grants from the National Institute on Drug Abuse, Centers for Disease Control and Prevention, National Center for Health Statistics, U.S. Department of Health and Human Services, Robert Wood Johnson Foundation, William T. Grant Foundation, and the Massachusetts Department of Public Health. Her professional contributions have been recognized by numer- ous professional and government organizations. These awards include: an Honorary Doctoral Degree in Humane Letters from Simmons College; the American Psychological Association's Early Career Award for Contributions to Psychology in the Public Interest; the American Psychological Association Award for Women's Health Research; the Association of Women in Psychology's Publication Award; the Massachusetts Public Health Association's Alfred Frechette Award for Contributions to Public Health; the Hispanic Mental Health Professional Association's Rafael Tavares Award for Research, and the American Psychological Association Dalmas Taylor Award as well as awards from various community organizations. Dr. Amaro serves on the National Steering Comittee of the National Hispanic Science Network on Drug Abuse.

William A. Carlezon, Jr., Ph.D.

Bill Carlezon, Ph.D. is an Associate Professor of Psychiatry at Harvard Medical School. He is the Founder and Director of the Behavioral Genetics Laboratory, and is also Director of an academia-industry cooperative initiative called the Medication Discovery and Development Laboratory. His research programs are located at McLean Hospital, one of the oldest and most renowned private psychiatric hospitals in the United States. Dr. Carlezon received a B.Sc. in Biology and Psychology from Bates College. After college, he worked for several years at Hoechst-Roussel Pharmaceuticals in the drug discovery laboratories and, for a short time, he helped to conduct Phase II clinical trials of a novel treatment for dementia. He then received his Ph.D. in Psychology at Concordia University in Montreal, and trained as a Postdoctoral Associate in Molecular Biology in the Department of Psychiatry at Yale University School of Medicine. He has received several awards for his research, including a Young Investigator Award from the National Alliance for Research on Schizophrenia and Depression (NARSAD), and his research is funded by federal grants from the National Institute on Drug Abuse (NIDA) and National Institute of Mental Health (NIMH). In 2003, his contribu- tions to the study of the neurobiology of addiction and mood disorders were recognized by the White House, in the form of the Presidential Early Career Award for Scientists and Engineers (PECASE). The main objective of Dr. Carlezon's research is to use preclinical (laboratory) models to understand how experience-driven changes in the molecular biology of the brain lead to maladaptive behaviors such as drug addiction, depression, and post-trau- matic stress disorder (PTSD).

18 Presenters

Felipe González-Castro, M.S.W., Ph.D.

Felipe González Castro received his Ph.D. in Clinical Psychology from the University of Washington in 1981. He is currently Professor of Clinical Psychology at Arizona State University. He has published over 50 journal articles and chapters in various health- related areas. His research is focused on motivational factors in drug abuse prevention, treatment, and relapse as well as incrementing cultural competence theory in program development and implementation, and in professional development. Dr. González- Castro has studied Hispanic health issues in the areas of health promotion and disease prevention in drug and tobacco use, cancer, diabetes mellitus, AIDS, and coronary heart disease. This research has been supported by grants from various agencies such as the National Institute on Drug Abuse, the National Cancer Institute, COSSMHO, and the Arizona Department of Health Services, among others. Dr. González-Castro has been widely recognized for his contributions and has received the National Hispanic/Latino Community Prevention Network Outstanding Achievement Award for Research. Dr. Gonzalez-Castro is currently serving on the Board of Directors of the Society for Prevention Research. He is also serving on the NIH Center for Scientific Review’s Epidemiology of Cancer (EPIC) Study Section.

Steven R. López, Ph.D.

Steven R. López received his doctorate in Clinical Psychology from the University of California, Los Angeles in 1983. He is currently Professor of Psychology and Psychiatry at the University of California, Los Angeles. He has published over 50 articles and chapters in the areas of the influence of sociocultural factors on psychopathology, assessment, and inter- vention of Latinos and other ethnic minority groups. His current research focuses on the identification of behaviors that underlie Mexican American family warmth in an effort to prevent relapse. This research is funded by a grant from the National Institute of Mental Health. Dr. López has been recognized for his contributions and has received the Distinguished Teaching Award from the Department of Psychology at UCLA. He also was one of the five sci- ence editors for the Surgeon General’s Supplemental Report on Mental Health: Culture, Race and Ethnicity.

Charles Martínez, Ph.D.

Dr. Charles Martínez is a Clinical Psychologist and Research Scientist at the Oregon Social Learning Center (OSLC) in Eugene. He is the principal investigator on the NIDA- funded Latino Youth and Family Empowerment (LYFE) Project. The main goals of the LYFE Project are to develop, implement, and test the efficacy of a culturally specified family intervention for Latino youngsters at risk for substance use and related problem behaviors. He also directs the Oregon Prevention Research Center's Latino Research Team in collaboration with other OSLC scientists, and partners from the local Latino community. His clinical and research interests center largely on identifying factors that promote healthy adjustment of families and children following stressful life events (such as changes in family structure, socioeconomic status, physical and/or emotional health, and immigration status), taking into consideration the cultural contexts in which families operate. He is interested in developing prevention theory and intervention models for multicultural relevance.

19 Presenters Diana Martínez, M.D.

Diana Martínez received her M.D. from Cornell University Medical College in 1994. She is currently Assistant Professor of Clinical Psychiatry at Columbia University/ New York Psychiatric Institute. She has published over 10 journal articles in the areas of mental illness and substance abuse. Her current research on cocaine abuse is sup- ported by the Mentored Clinical Scientist Development Award from NIDA. She is also the recipient of the Young Investigator Award from NARSAD. Dr. Martínez has been recognized for her contributions and has received the American Psychiatric Association Award for Junior Investigators; the American Psychiatric Association/Mead Johnson Award, and the American Psychiatric Association/ PMRTP Award. Joe L. Martínez, Jr., Ph.D.

Joe L. Martínez, Jr. completed a Ph.D. at the University of Delaware in 1971 with a special- ization in Physiological Psychology. Currently, he is the Ewing Halsell Professor of Neuroscience at the University of Texas at San Antonio. He has published over 160 journal articles and chapters in the areas of gene analysis of long-term potentiation, neurobiologi- cal basis of learning and memory, and psychopharmacology. Dr. Martínez is the Program Director of the Cajal Neuroscience Research Center at the University of Texas at San Antonio. His research is sponsored by grants from the National Institute on Drug Abuse, the National Institute of Neurological Disorders and Stroke, the National Institute of Mental Health, and the National Center for Research Resources. Dr. Martínez has been rec- ognized for his contributions and has received the La Raza Recognition Award from the University of California and the American Association for the Advancement of Science Mentor Award for Lifetime Achievement, among others. Additionally, he serves on the National Steering Committee of the National Hispanic Science Network on Drug Abuse.

Eleanor McLellan-Lemal, M.A.

Eleanor McLellan-Lemal, M.A., is a behavioral scientist with the Centers for Disease Control and Prevention in Atlanta, Georgia. Her research interests and experience include applied anthropology, particularly in HIV pre- vention and clinical trials; social networks, drug abuse, and HIV transmission; public health; community devel- opment; public gender issues; ethnic relations; and research methodology. Her work has included the develop- ment of AnSWR: Analysis software for Word-based Records and ethnography with injection drug users.

María Elena Medina-Mora, Ph.D.

Dr. María Elena Medina-Mora is the Director of Epidemiology and Psychosocial Research at the National Institute on Psychiatry, México, where she coordinates the work of more than 70 full-time researchers and other health professionals. She is also responsible for the area of Public Mental Health for Masters and Ph.D. degrees in Health Sciences at the School of Medicine of the National Autonomous University of México, UNAM. She has worked as a full-time researcher in the drug field for the past 30 years. Her areas of inter- est are methodological, psychosocial, and epidemiological issues as they relate to addic- tions and mental health. She has conducted national household surveys, high school sur- veys, surveys among street children and studies among hidden populations. Cross-cul- tural research has also been one of her main interests. Her Ph.D. dissertation explored pat- terns of alcohol abuse and socio-cultural factors in urban and rural areas with a high level of migration to the United States. She worked with Raúl Caetano in the comparison of information from México and the United States and published the results in 1986. She coordinated the Mexican Survey on Mental Health and Use of Services as part of the WHO 2000 Initiative on Mental Health. She has had extensive experience in international Boards. She has served as advisor for the World Health Organization and the Pan-American Health Organization since 1976. She has been a member of the World Health Organization Expert Committee on Addictions since 1986 and a member of the International Narcotics Control Board since 2000. She is a well-known scientist with her main contributions being in the development and adaptation of methodologies to examine socio-cultural factors relat- ed to substance abuse and in the assessment of the drug scene in México.

20 Presenters Katheleen Ries Merikangas, Ph.D.

Kathleen Ries Merikangas is the Chief of the Section on Developmental Genetic Epidemiology in the Mood and Anxiety Disorders Program and Associate Director for Epidemiology at NIMH. Prior to joining the Intramural Program at NIMH, Dr. Merikangas was Professor of Epidemiology and Public Health, Psychiatry and Psychology at the Yale University School of Medicine, where she served as Director of the Genetic Epidemiology Research Unit in the Department of Public Health. Dr. Merikangas has been actively engaged in genetic epidemiologic research for more than 15 years. She has been the principal investi- gator, co-investigator or consultant to numerous federally and non-federally funded research grants. The major areas of her research are: (1) studies of the patterns and components of familial aggregation of mental disorders and familial mechanisms for comorbidity of mental and medical disorders; (2) identification of early signs and risk factors for psychiatric disorders among high and low risk youth using prospective longitudi- nal high risk studies; and (3) large scale population based studies of mental disorders including high risk designs and prospective longitudinal research. Dr. Merikangas is an author of more than 200 scientific publications and has presented lectures throughout the U.S. and in more than 20 countries. She is on the Editorial Board of several scientific journals and has been on the scientific advisory boards of numerous organizations and academic insti- tutions including the John D. and Catherine T. MacArthur Foundation Research Networks on Psychobiology of Affective Disorders and Psychopathology and Development; the Robert Wood Johnson Foundation Research Network on the Etiology of Tobacco Dependence; the Institute of Medicine Panel on Neuroscience and Behavior; and the Max Planck Institute for Psychiatry in Munich, Germany. She recently chaired the Genetics Committee of the NIMH Strategic Plan for Mood Disorders. At NIMH, she plans to develop a program in genetic epidemiolo- gy integrated with statistical genetics and molecular biology to support research in the Mood and Anxiety Disorders Program.

Patricia Molina, M.D., Ph.D.

Patricia Molina completed medical school in 1984 at the Universidad Francisco Marroquín and a rotational internship at the Hospital General San Juan de Dios in Guatemala. In 1990, she obtained a Ph.D. in Physiology at Louisiana State University in New Orleans. She is cur- rently Associate Professor at the Department of Physiology at Louisiana State University. She has published over 60 journal articles and chapters in the areas of alcohol consumption, the role of the nervous system in response to stress, and the role of the neuroendocrine system in modulation of pro-inflammatory responses to hemorrhagic shock. Her research is focused on neural control of hemorrhage-induced tissue cytokine production; the mechanisms involved in the accelerated muscle wasting associated with AIDS, and how chronic alcohol consumption affects the course and progression of AIDS-associated wasting. This research is funded by the Office of Naval Research, the Louisiana State University Health Sciences Center Alcohol Research Center, and the Louisiana Health Excellence Fund. Dr. Molina has been recognized for her contributions and received the Outstanding Graduate Student Award from Louisiana State University Medical Center in 1989. Dr. Molina serves on the National Steering Committee of the National Hispanic Science Network on Drug Abuse.

Eduardo Montalvo, Ph.D.

Dr. Eduardo Montalvo joined the Center for Scientic Review, National Institutes of Health, as scientific review administrator in 2000. He currently coordinates the review of two AIDS-relat- ed research study sections. Dr. Montalvo grew up in the Río Grande Valley in south Texas and received his undergraduate degree in microbiology from the University of Texas at Austin. He also holds a Masters degree from the School of Public Health at the University of Washington and a Ph.D. in microbiology from the University of Texas Health Science Center in San Antonio. After completion of his Ph.D., he received postdoctoral training in the Department of Molecular Biology at Princeton University. He returned to the University of Texas Health Science Center in San Antonio, where he was an assistant professor spearheading research on cellular proteins critical to the life cycle of the Epstein-Barr virus. He also investigated various aspects of human herpesvirus 8, a virus associated with the development of Kaposi’s sarcoma in AIDS patients.

21 Presenters

Iván Montoya, M.D., M.P.H.

Iván Montoya, born in Medellín, Colombia, received his M.D. degree from the University of Antioquía (Colombia) and M.P.H. from the Johns Hopkins School of Public Health. He did residency training in Psychiatry at the San Vicente de Paul Hospital (Colombia) and University of Maryland Hospital. He was a Hubert H. Humphrey Fellow in Drug Abuse at the Johns Hopkins School of Public Health and a Visiting Fellow at the Intramural Research Program of the National Institute on Drug Abuse (NIDA). He has been Director of the Public Mental Health Program at the University of Antioquía, Consultant for the World Health Organization/Pan American Health Organization, and Director of the Practice Research Network of the American Psychiatric Association. He has published extensively in the fields of prevention and treatment (pharmacological and non-pharmacological) of substance use disorders. Currently, he works in the NIDA Division of Treatment Research and Development.

Susan F. Newcomer, Ph.D.

Susan F. Newcomer is a statistician/demographer at NIH. She holds a 1983 Ph.D. in sociology and population studies from the University of North Carolina, and a 1962 B.A. from Barnard College in psychology and Chinese. From 1984-1988, she was the Director of Education, Planned Parenthood Federation of America. Before obtaining her degree she had been acting director of a YWCA on a college campus, and director of a daycare center. At NIH she is the project officer on a portfolio of research grants on fertility, HIV risk, contra- ceptive use, reproductive health and adolescent risk behaviors, including interventions to reduce risk in youth and adults. Another of her responsibilities is to develop and maintain contacts with behavioral and social sci- ence researchers in the U.S. and in other countries, and to provide assistance to those wishing to apply for funding to the NIH. Her publications have dealt with adolescent sexuality, fertility, and sexuality education.

Alexander N. Ortega, Ph.D., M.P.H.

Alexander N. Ortega is Associate Professor, Division of Health Behavior and Health Promotion, at The Ohio State University. Dr. Ortega received his B.A. in economics from the University of New Mexico, an M.P.H. in epidemiology and biostatistics from Boston University, and a Ph.D. in epidemiological science from the University of Michigan. From 1998-2003, he was Assistant Professor of health policy and administration at Yale University and faculty fellow of the Jonathan Edwards College of Yale College. In 2001, he was a Senior-Scholar-in-Residence at the Center for Primary Care Research at the Agency for Healthcare Research and Quality (AHRQ) and from 1995-1998 he was a Senior Research Associate in the W.M. Krogman Center for Research in Child Health and Development at the University of Pennsylvania in Philadelphia. He has published in a wide variety of health services research and clinical journals. His articles are published in journals such as Medical Care, Pediatrics, American Journal of Psychiatry, Journal of Nervous and Mental Disease, Psychosomatics, Mental Health Services Research, and Annals of Allergy, Asthma and Immunology. Dr. Ortega is frequently invited to speak at leading research uni- versities, national conferences, and government meetings on topics within children's health services research and policy and mental health services research. He currently is a permanent member of the Health Systems Research (HSR) study section at AHRQ, and he has served as a permanent or temporary study section mem- ber on other NIH and CDC panels, including the Behavioral and Social Consequences of HIV/AIDS Study Section (formerly AIDS and Related Research Study Section 8) at NIH.

22 Presenters

Hilda Pantín, Ph.D.

Hilda Pantín received her Ph.D. in Clinical Psychology from the University of Miami in 1982. She is currently Clinical Assistant Professor of Psychiatry and Behavioral Sciences at the University of Miami School of Medicine, Center for Family Studies. She has published over fifteen journal articles and chapters in the areas of family- based prevention of adolescent substance abuse, HIV, and other problem behaviors. One of these publications was recently awarded the American Association of Marriage and Family Therapy's "Outstanding Research Publication Award" for 2003. Her current research is focused on prevention of drug abuse, HIV, and other prob- lem behaviors in Hispanic adolescents. This research is supported by grants from the National Institute of Mental Health.

Angela Patattucci-Aragón, Ph.D.

Dr. Ángela Pattatucci Aragón is Director of the Center for Evaluation and Sociomedical Research and Professor of Health Services Administration in the Graduate School of Public Health at the University of Puerto Rico Medical Sciences Campus. Prior to joining the facul- ty at UPR she spent three years at the NIH Center for Scientific Review, where she directed the scientific review of HIV/AIDS applications submitted for funding consideration with a focus on areas of behavioral science, prevention and epidemiology, and clinical sciences. Her doctoral research was completed at Indiana University and focused on behavior genetics and human sexuality. Her postdoctoral training was at NIH in epidemiology and adolescent men- tal health, spending two years with NICHD and an additional two years with NCI and the NIH Clinical Center. She then spent two years as a professor of epidemiology and behavioral science at the Ponce School of Medicine in Puerto Rico, followed by a year at the University of Puerto Rico as director of evaluation and assessment for the Puerto Rico Statewide Systemic Initiative (SSI), University of Puerto Rico-Río Piedras. The SSI program, aimed at all public school students in Puerto Rico, is an intervention designed to increase students' knowledge and skills in science and math. Before returning to the NIH she spent a year at the University of Louisville as visiting professor of women's studies and psychology. Her research interests center on HIV/AIDS, gender and sexuality, drug policy, and program evaluation.

Tracy Enright Patterson, M.A.

Tracy Enright Patterson is a Research Associate at the Wake Forest University School of Medicine (WFUSM). As part of her work at WFUSM, Ms. Patterson serves as deputy director of the Robert Wood Johnson Foundation Substance Abuse Policy Research Program. For seven years prior to taking her current position with WFUSM, Ms. Patterson was the Field Director for Program Management with N.C. Project ASSIST, a statewide tobacco control program. Prior to that, she worked as the Chronic Disease Prevention Manager at the Guilford County Health Department in Greensboro, N.C. She also coordinated an international women's health program (in Latin America and the Caribbean) as a Program Officer at the Pan American Health Organization in Washington, D.C. Ms. Patterson has a bachelor's degree in government from the University of Notre Dame and a master's degree in public policy from Duke University.

23 Presenters

Jesús Ramírez-Valles, Ph.D., M.P.H.

Jesús Ramírez-Valles is an Associate Professor in Community Health Sciences at the University of Illinois-Chicago School of Public Health. He obtained his masters in pub- lic health and his doctoral degree from the University of Michigan. His teaching and research interests are in health education and promotion and the sociology of health. Particularly, his research includes community mobilization for health, youth health, gender and race in health promotion, and HIV/AIDS and substance use prevention. He conducts qualitative and quantitative research in both the United States and Latin America. Dr. Ramírez-Valles has published in the major public health journals, and serves on the editorial board of two scientific journals and as a reviewer for many other journals. He has been awarded research grants from the National Institutes of Health and a Golden Apple for Excellence in Teaching.

George A. Ricaurte, M.D., Ph.D.

George A. Ricaurte received his Ph.D. in Pharmacology from the University of Chicago in 1979 and his M.D. from Northwestern University Medical School in 1981. He is currently Associate Professor in the Department of Neurology at the Johns Hopkins University School of Medicine, Johns Hopkins Bayview Medical Center. He has published over 110 journal articles in the area of biomedical research. His current research on MDMA and methamphetamine neurotoxicity in humans is supported by grants awarded by NIH/NIDA. Dr. Ricaurte has been recognized for his contributions and has received awards such as the Medical Scientist Training Program Scholar, the National Science Foundation Summer Science Program Scholar, and the Research Scientist Development Award.

Rafaela R. Robles, Ed.D.

Rafaela R. Robles received her Ed.D. in Sociology from Columbia University in 1970. She is currently the Director of the Caribbean Basin / Hispanic Addiction Technology Transfer Center, and Senior Scientist and Director of the Center for Addiction Studies of the Universidad Central del Caribe, School of Medicine. She has published over 40 journal articles and chapters in the areas of drug abuse, mental health and health care services. Her current research is focused on drug abuse and HIV prevention, transferring drug abuse research to practice, mentoring minority researchers, and a comparative study on HIV prevention. This research is supported by grants from the National Institute on Drug Abuse and the Center for Substance Abuse Treatment, among others. Dr. Robles has been recognized for her contributions and has received honors and awards from the Universidad Central del Caribe, School of Medicine (Professoris Eminentis, 1998) and the National Hispanic Science Network on Drug Abuse (Outstanding Mentorship Award, 2001). Dr. Robles serves on the National Steering Committee of the National Hispanic Science Network on Drug Abuse.

24 Presenters

Mónica S. Ruiz, Ph.D., M.P.H.

Mónica S. Ruiz, Ph.D., M.P.H. is a Program Officer and behavioral scientist in the Prevention Sciences Branch of the Division of AIDS, at the National Institutes of Allergy and Infectious Diseases, National Institutes of Health. In this capacity, she works primari- ly with the HIV Prevention Trials Network, which is an NIH-sponsored worldwide collab- orative clinical trials network that develops and tests the safety and efficacy of primarily non-vaccine interventions designed to prevent the transmission of HIV. Prior to joining NIAID, Dr. Ruiz was a Senior Program Officer at the Institute of Medicine and the Study Director for the committees that produced No Time to Lose: Getting More from HIV Prevention (published in 2000) and The Future of the Public's Health in the 21st Century (published in 2002). In 1999, she was a Research Associate at the University of Connecticut, where she worked with colleagues at the Yale AIDS Program in developing a clinician-delivered prevention intervention for HIV-infected persons in outpatient care. In 1998, Dr. Ruiz served as the Counseling and Social Support Advisor for the Joint United Nations Programme on HIV/AIDS (UNAIDS) in Geneva, Switzerland. While in that post, she also served as the UNAIDS liaison to the Multi-site Voluntary HIV Counseling and Testing Efficacy Study. Dr. Ruiz received her doctorate in Preventive Medicine from the University of Southern California School of Medicine, and her Masters degree in Public Health from the University of California, Berkeley. She also completed a post-doctoral fellowship at the Center for AIDS Prevention Studies at the University of California, San Francisco.

Daniel Santisteban, Ph.D.

Daniel Santisteban earned his Ph.D. in Clinical Psychology from the University of Miami in 1991 and completed his internship at Bellevue Hospital/NYU. He is currently Research Associate Professor of Psychiatry and Behavioral Sciences at the University of Miami School of Medicine, Center for Family Studies. Dr. Santisteban has published over 30 arti- cles and chapters on issues of family treatment, the impact of culture-related factors on the development and treatment of substance abuse, treatment outcome research, and on the treatment of co-occurring disorders in adolescents. Dr. Santisteban has also specialized in the development and testing of novel treatments for special populations. Dr. Santisteban is Principal Investigator on a NIDA-funded treatment development grant focused on the development of a specialized family treatment for Hispanic adolescents, and is Co-Principal Investigator on the NIDA-funded Florida Node of the Clinical Trials Network. Dr. Santisteban conducts training and supervision in family therapy and is also a standing member of the NIDA treatment research grant review committee (NIDA- E). In the Clinical Trials Network, Dr. Santisteban is leading efforts with treatment funders and treatment agen- cies in the State of Florida to bring empirically supported treatments to front line providers and agencies. Dr. Santisteban serves on the National Steering Committee of the National Hispanic Science Network on Drug Abuse.

25 Presenters

José Szapocznik, Ph.D.

José Szapocznik received his Ph.D. in Clinical Psychology from the University of Miami in 1977. He is currently Professor of Psychiatry and Behavioral Sciences, Psychology and Counseling Psychology at the University of Miami. Dr. Szapocznik is Director of the Center for Family Studies at the University of Miami School of Medicine. He is the founder and former director of the Miami World Health Organization Collaborating Center for Research and Training on Mental Health, Alcohol and Drug Dependence. He has published over 150 journal articles and chapters in the areas of Hispanic families, families and HIV, family therapy and family-based prevention, and mental health and drug abuse policy. His current research is focused on drug abuse, HIV prevention in Hispanic adolescents, therapy with HIV+ African American women, and the role of the built environment in adolescent delinquency as well as in Hispanic elders’ behavioral health. This research is supported by grants from the National Institute on Drug Abuse, the National Institute of Mental Health, and the National Institute on Environmental Health Sciences, among others. Dr. Szapocznik has been recognized for his contributions and has received the Presidential Award from the Society for Prevention Research, the Lifetime Achievement Award from the Latino Behavioral Health Institute, and the Substance Abuse Prevention Research Award from the U.S. Center for Substance Abuse Prevention, among others. He is a member of the National Advisory Council on Drug Abuse, NIDA and has been a member of the National Advisory Council for the NIMH and the Center for Substance Abuse Prevention. Dr. Szapocznik serves as Chair of the National Hispanic Science Network on Drug Abuse. Avelardo Valdéz, Ph.D.

Dr. Avelardo Valdéz received his Ph.D. in Sociology from the University of California, Los Angeles, in 1979. He is currently a Professor in the Graduate School of Social Work at the University of Houston. He was a Fulbright Scholar at the Universidad Nacional Autónoma de México, México, D.F. His research centers on drugs, violence, adolescent gangs, and sex workers in South Texas and the U.S./ México border. A primary focus of his research has been on the relationship between substance abuse and violence among high-risk groups. Dr. Valdéz has developed an expertise in accessing hidden populations through a research strategy that includes field methods and survey sampling procedures. He is a recipient of numerous federal research grants from the National Institutes of Health, Centers for Disease Control and Prevention, and Substance Abuse and Mental Health Services Administration. His most recent NIH grant focuses on Hispanic heroin users and the transition to injecting and HIV. Dr. Valdéz serves on the National Steering Committee of the National Hispanic Science Network on Drug Abuse.

William A. Vega, Ph.D.

William A. Vega is Professor of Psychiatry at the Robert Wood Johnson Medical School- University of Medicine and Dentistry of New Jersey. He is also Director, Research Division, Behavioral Research and Training Institute, University Behavioral Health Care. Dr. Vega has conducted field and clinical research projects on health, mental health, and substance abuse in various regions of the United States and Latin America. His specialty is comparative epidemiologic and services research with Latino adolescents and adults. He has published over 135 articles and chapters on these topics, in addition to several books. In 2002, Dr. Vega was awarded the Culture, Community, and Prevention Science Award by the Society for Prevention Research, and the National Award of Excellence in Research by a Senior Scientist by the National Hispanic Science Network on Drug Abuse. Dr. Vega is President of the National Latino Council on Tobacco and Alcohol prevention, and a founding mem- ber of the International Consortium of Psychiatric Epidemiology of the World Health Organization, a member of the Institute of Medicine-Board of Health Promotion and Disease Prevention, and a member of the Robert Wood Johnson Foundation Advisory Group for Health Policy Scholars. Dr. Vega serves on the National Steering Committee of the National Hispanic Science Network on Drug Abuse. 26 Presenters

Mildred Vera, Ph.D.

Mildred Vera received her Ph.D. in Psychology from the University of Puerto Rico in 1989. She is currently a Professor in the Department of Health Services Administration at the University of Puerto Rico. She has pub- lished over 30 journal articles and chapters in the areas of mental health care among the poor; gender and health services use; and drug prevention research with minority populations. Her current research is focused on Latino research programs. This research is supported by the National Institutes of Health.

María Cecilia Zea, Ph.D.

María Cecilia Zea received her Ph.D. in Clinical/Community Psychology from the University of Maryland in 1990. She is currently a Professor of Psychology at the George Washington University. She has published over 40 journal articles and chapters and an edited book in the area of Ethnic Minority Psychology. Her current research is focused on the disclosure of HIV status and sexual risk among Latino gay men. This research is supported by grants from the National Institutes of Mental Health and the National Institute for Child Health and Human Development. Dr. Zea has been recognized for her contributions and has received awards from the Collaborative Program for AIDS Prevention Research in Minority Communities, Center for AIDS Prevention Studies, University of San Francisco (1997-1999), and the Research Enhancement Incentive Award from George Washington University (1993, 1994, 1998-2001), among others. Dr. Zea is a Fellow of the American Psychological Association.

Jon Kar Zubieta, M.D., Ph.D.

Jon-Kar Zubieta, M.D., Ph.D. is a Senior Associate Research Scientist in the Mental Health Research Institute and Associate Professor in the Departments of Psychiatry and Radiology (Division of Nuclear Medicine) at the University of Michigan, where he has been a faculty member since 1995. He has completed formal training in the Neurosciences (Ph.D.), Psychiatry and Nuclear Medicine (Board Certified in both). He is Director of the Depression Center and the Neuroimaging Core in the Department of Psychiatry at the University of Michigan. He is an internationally recognized expert in the area of neurochemical imaging with PET and functional neuroimaging. His work involves the quantification of metabolism, blood flow, and neuroreceptor sites in human subjects, including cholinergic, aminergic, and opioid markers. He applies these tech- niques and other ancillary measures to the study of the neurobiology of mood regulation, stress responses and the addictions.

27 2003 Conference Planning Subcommittee

William A. Vega, Ph.D. Patricia Molina, M.D., Ph.D. Chair, 2003 NHSN Conference Planning Subcomittee Associate Professor Professor Department of Physiology Department of Psychiatry Louisiana State University UMDNJ/ Robert Wood Johnson Medical School

Iván Montoya, M.D., M.P.H. Hortensia Amaro, Ph.D. Medical Officer Distinguished Professor & Director Division of Treatment Research & Development Institute on Urban Health Research National Institute on Drug Abuse Bouvé College of Health Sciences Northeastern University J. Bryan Page, Ph.D. Professor & Chair Ana Anders, L.I.C.S.W. Department of Anthropology Senior Advisor University of Miami Special Populations Office National Institute on Drug Abuse Angela Pattatucci-Aragón, Ph.D. Professor Marie A. DiCowden, Ph.D. Graduate School of Public Health Executive Director University of Puerto Rico The Biscayne Institutes of Health & Living, Inc.

Rafaela R. Robles, Ed.D. Steve R. López, Ph.D. Professor Professor Department of Community Health Department of Psychology Universidad Central del Caribe University of California at Los Angeles

Eugene Somoza, M.D., Ph.D. Charles Martínez, Ph.D. Professor Clinical Psychologist & Research Scientist Department of Psychiatry Oregon Social Learning Center University of Cincinnati

Joe L. Martínez, Ph.D. José Szapocznik, Ph.D. Ewing Halsell Professor of Neuroscience Professor & Director Department of Biology Center for Family Studies University of Texas at San Antonio Department of Psychiatry & Behavioral Sciences University of Miami School of Medicine

28 Conference Objectives

"Stress and Addiction: From Molecule to Neighborhood" will offer a scholarly program of presentations focusing on the current state of knowledge in Hispanic drug abuse research, along with an applied, interactive workshop on research funding opportunities and career development issues. The conference will also feature the National Hispanic Science Network on Drug Abuse's first annual Poster Session and Mentoring Luncheon.

The conference is designed to identify scientific research gaps and research opportunities, to promote interdisciplinary research collaborations, to foster the mentoring and career devel- opment of Hispanic early career scientists and graduate students, and to build and strength- en a network of investigators and graduate students who are dedicated to advancing the field of Hispanic drug abuse research and to reducing health disparities between Hispanics and other populations.

Upon completion of the 2003 conference, participants will be conversant with:

* New research findings in the areas of stress and addiction; the neurobiology of the stress response; the neurobiological substrates of licit and illicit drug abuse and dependence; familial, cultural and community risk factors; addiction treatment and relapse prevention; and, community-based substance abuse prevention interventions;

* The findings and recommendations of the National Hispanic Science Network on Drug Abuse's National Strategic Plan on Hispanic Drug Abuse Research;

* Research funding opportunities from the National Institutes of Health, the Centers for Disease Control and Prevention, and the Robert Wood Johnson Foundation; and,

* The grant proposal scientific review process and grant post-submission issues.

Accreditation

This program is co-sponsored by The Biscayne Institutes of Health & Living, Inc. The Biscayne Institutes of Health and Living, Inc. is approved by the American Psychological Association to offer continuing education to psychologists. The Biscayne Institutes of Health & Living, Inc. maintains responsibility for the program.

Credit Hours

The Biscayne Institute of Health & Living, Inc. designates this educational activity for 15 credit hours toward continuing education for Psychologists.

29 NATIONAL HISPANIC SCIENCE NETWORK ON DRUG ABUSE

National Office Center for Family Studies Department of Psychiatry & Behavioral Sciences University of Miami School of Medicine 1425 N.W. 10th Avenue, 3rd Floor Miami, FL 33136 305.243.2340 phone 305.243.5577 fax www.hispanicscience.org

National Office Staff Yolanda Mancilla, Ph.D., National Coordinator Grettel Fernández-Suárez, Program Assistant Rosa E. Verdeja, M.Ed., Program Assistant

Conference Support Staff: Patricia Bronfman Angela Flory Jeff Appelbaum

Northeastern University Staff Sandra Arévalo, Graduate Assistant María Cristina Santana, Graduate Assistant Amanda Navarro, M.P.H., Project Director, National Strategic Plan

National Institute on Drug Abuse Ana Anders, L.I.C.S.W., Program Officer Special Populations Office

Jerry Flanzer, D.S.W., Alternate Program Officer Acting Deputy Branch Chief, Services Research Branch

Very Special Thanks To:

Ana Anders, L.I.C.S.W., NIDA Special Populations Office Victor Capoccia, Ph.D., Robert Wood Johnson Foundation Manuel Díaz, Precise Printing, Inc. Ernest Marquez, Ph.D., National Institute of Mental Health Tracy Enright Patterson, M.A., Wake Forest University School of Medicine Rafaela R. Robles, Ed.D., Universidad Central del Caribe Wanda Rodríguez, J.D., LL.M., Caribbean Basin Addiction Technology Transfer Center Diana Soto, FourSeasons Travel

30 Notes

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33 Notes

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